Inflammatory bowel disease Pathophysiology
Inflammatory bowel disease (IBD) is depicted by chronic deteriorating intestinal inflammation. IBD comprises Crohn’s disease (CD) and ulcerative colitis (UC), which are distinct chronic bowel-relapsing inflammatory disorders (Zhang & Li, 2014).
Current research specified that the individual’s genetic receptiveness, external environment, intestinal microbial flora, and immune responses altogether are involved and functionally incorporated in the pathogenesis of IBD (Zhang & Li, 2014).
Chron’s Disease can begin transmural inflammation and affect any part of the gastrointestinal tract, usually the terminal ileum or the perianal region, in a non-continuous type (Zhang & Li, 2014). Unlike Ulcerative Colitis, Chron’s Disease is oftenconnected with impediments such as abscesses, fistulas and strictures.
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