CURRICULUM VITAE
Jerimy C. Polf, Ph.D., DABR Assistant Professor, Department of Radiation Oncology University of Maryland School of Medicine DATE: 12/10/2013 CONTACT INFORMATION Department of Radiation Oncology 22 South Greene Street Baltimore MD 21201 Room Number: 218 Gray Lab Phone: (410) 706-6512 Fax: (410) 328-2618 Email: jpolf@som.umaryland.edu Foreign Languages: Spanish (working knowledge) EDUCATION 1998 B.S., Applied Physics, Oklahoma State University 2000 M.S., Photonics, Oklahoma State University, Thesis Advisor – Stephen McKeever, Thesis Title: THE ROLE OF OXYGEN VACANCIES IN THERMOLUMINESCNECE PROCESSESS IN AL203:C 2002 PhD., Photonics, Oklahoma State University, Thesis Advisor – Stephen McKeever, Thesis Title: A STUDY OF OPTICALLY STIMULATED LUMINECENCE IN Al2O3 FIBERS FOR THE DEVELOPMENT OF A REAL-TIME, FIBER OPTIC DOSIMETRY SYSTEM
POST GRADUATE EDUCATION AND TRAINING 8/2002−2/2003 Postdoctoral Fellowship, Oklahoma State University, Stillwater, OK, Stephen McKeever, Ph.D., 8/2002−2/2003 2/2003−3/2005 Postdoctoral Fellowship, University of Texas, M. D. Anderson Cancer Center, Houston, TX, Wayne Newhauser, Ph.D., 2/2003−3/2005
CERTIFICATIONS Board Certification 06/2008 American Board of Radiology, 4590
MEDICAL LICENSURES Inactive Texas, MP10168
EMPLOYMENT HISTORY Academic Appointments 4/2005−12/2007 Instructor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 1/2008−6/2011 Assistant Professor, Department of Radiation Physics, Division of Radiation
Jerimy C. Polf, Ph.D.
Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX Assistant Professor, Department of Physics, Oklahoma State University, Stillwater, OK 7/29/2013-present Assistant Professor, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore MD 7/2011-07/2013
PROFESSIONAL MEMBERSHIPS/ACTIVITIES American Association of Physicists in Medicine (AAPM), 2005-present
HONORS AND AWARDS 2000 IGERT Fellow, National Science Foundation, 2001 Best Poster Presentation, International Solid State Dosimetry Organization 2006 The Farrington Daniels Award for Top Publication in Medical Dosimetry, American Association of Physics in Medicine 2008 American Physical Society Showcase Selection in Biological Physics, Virtual Journal of Biological Physics Research 2011 American Physical Society Showcase Selection in Biological Physics, Virtual Journal of Biological Physics Research 2011 Outstanding Contributions in Medical Physics Research Award, Department of Radiation Physics, University of Texas M.D. Anderson Cancer Center 2011 American Physical Society Showcase Selection in Nanoscale Science, Virtual Journal of Nanoscale Science and Technology CLINICAL ACTIVITIES Clinical Expertise Board Certified Medical Physicist Scope of Clinical Practice 2/2005 – 7/2011 Clinical Medical Physics Services, MD Anderson Cancer Center, Houston TX Treatment Linear Accelerator Annual Calibration and monthly Quality Assurance measurements. Patient treatment plan development, review and checking for Photon, Electron, and Proton radiotherapy treatments. Patient CT simulations, including 4DCT scanning, for treatment planning purposes Daily patient setup verification for Steroetactic Radiotherapy treatments for lung cancer. Treatment beam calibration and patient specific MU measurements for Proton Radiotherapy ACADEMIC SERVICE Institutional Service 2011-2013 Medical Physics Program Director, Department of Physics, Oklahoma State University, **Oversaw development of student curriculum, clinical rotations and CAMPEP accreditation of the Medical Physics Graduate Program.
LOCAL AND NATIONAL SERVICE N/A
TEACHING SERVICE Formal Teaching Courses Taught (Oklahoma State University) SPRING 2013 PHYS5593 The Physics of Radiation Oncology, 4 graduate students FALL 2012 PHYS5533 The Physics of Medical Imaging, Fall 2012, 2 graduate students PHYS5523 Radiation Dosimetry and Protection, 4 graduate students
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SUMMER 2012 PHYS5590 Clinical Aspects of Medical Physics, 1 graduate student SPRING 2012 PHYS5583 The Physics of Medical Imaging, 4 graduate students FALL 2011 PHYS5593 The Physics of Radiation Oncology, 5 graduate students
GRANT SUPPORT Active Grants None. Completed Grants 10/01/2012-09/30/2013 Jerimy Polf (Co-Inv, 10% effort; PI – Ashish Ranjan, PhD) “Targeting solid tumor by combining Proton Beam Radiotherapy (PBRT) and drug encapsulated thermosensitive liposomal nanoplatforms” Research Advisory Council Grant, Oklahoma State University Center for Veterinary Health Sciences Total Direct Costs: $29,200 Role: Developed irradiation and dosimetry method for cell culture irradiation in a clinical proton therapy beam 3/20/2009-3/20/2010
Jerimy Polf, (PI, 20%) “Imaging tumor hypoxia with proton beam radiotherapy” American Cancer Society, IRG-08-061-01 Total Direct Costs: $30,000
7/01/2010-6/30/2013
Jerimy Polf, (PI, 25%) “Real-time dose and tissue imaging during proton beam irradiation” NIH/NCI R21 CA137362-01A2 Total Direct Costs: $275,000
PATENTS, INVENTIONS, and COPYRIGHTS Patents Oklahoma State University, Polf JC, Gaza R, and McKeever SWS, Optically stimulated luminescence radiation dosimetry method to determine integrated doses and dose rates and a method to extend the upper limit of measurable absorbed radiation doses during irradiation, United States, 7,002,163, 2/21/2006, Issued
PUBLICATIONS Peer-Reviewed Journal Articles 1. Akselrod MS, Lucas AC, Polf JC, McKeever SWS. Optically Stimulated Luminescence in Al2O3. Radiat Prot Dosimetry 29:391-399, 1998. 2. McKeever SWS, Akselrod MS, Colyott LE, Agersnap-Larsen N, Polf JC, Whitley VH. Characterization of Al203 for use in Thermally Stimulated and Optically Stimulated Luminsescence Dosimetry. Radiat Prot Dosimetry 84:163-168, 1999. 3. Polf JC, McKeever SW, Akselrod MS, Holmstrom S. A real-time, fibre optic dosimetry system using Al2O3 fibres. Radiat Prot Dosimetry 100(1-4):301-4, 2002. 4. Bloom D, Evans DR, Holmstrom S, Polf JC, McKeever SWS, Whitley VH. Characterization of Al2O3 Single Crystals Grown by the Laser-Heated Pedestal Growth Technique for Potential Use in Radiation Dosimetry. Rad Meas 37(2):141-149, 2003. 5. Whitley VH, Yukihara EG, Polf JC, Klein D, McKeever SWS, Akselrod AE, Akselrod MS. The effects of deep trap population on the Thermoluminescence of AI203:C. Rad Meas 37:627-638, 2003.
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6. Polf JC, Yukihara EG, Akselrod MS, McKeever SWS. Real-time luminescence from AI203 fiber dosimeters. Rad Meas 38:227-240, 2004. 7. Polf JC, Newhauser WD. Calculations of neutron dose equivalent exposures from range-modulated proton therapy beams. Phys Med Biol 50(16):3859-73, 8/2005. 8. Ciangaru G, Polf JC, Bues M, Smith AR. Benchmarking analytical calculations of proton doses in heterogeneous matter. Med Phys 32(12):3511-23, 12/2005. 9. Polf JC, Newhauser WD, Titt U. Patient neutron dose equivalent exposures outside of the proton therapy treatment field. Radiat Prot Dosimetry 115(1-4):154-8, 2005. 10. Polf JC, Harvey MC, Titt U, Newhauser WD, Smith AR. Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification. Med Phys 34(11):4213-8, 11/2007. 11. Polf JC, Harvey MC, Smith AR. Initial beam size study for passive scatter proton therapy. II. Changes in delivered depth dose profiles. Med Phys 34(11):4219-22, 11/2007. 12. Newhauser W, Fontenot J, Zheng Y, Polf J, Titt U, Koch N, Zhang X, Mohan R. Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys Med Biol 52(15):4569-4584, 2007 13. Archambault L, Polf JC, Beaulieu L, Beddar S. Characterizing the response of miniature scintillation detectors when irradiated with proton beams. Phys Med Biol 53(7):1865-76, 4/7/2008. 14. Harvey MC, Polf JC, Smith AR, Mohan R. Feasibility studies of a passive scatter proton therapy nozzle without a range modulator wheel. Med Phys 35(6):2243-2252, 6/2008. 15. Titt U, Sahoo N, Ding X, Zheng Y, Newhauser W, Zhu X, Polf JC, Gillin MT, Mohan R. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions. Phys Med Biol 53(16):4455-4470, 7/2008. 16. Polf JC, Peterson S, Ciangaru G, Gillin M, Beddar A. Prompt gamma-ray emission from biological tissues during proton irradiation: a preliminary study. Phys Med Biol 54(3):731-743, 1/2009. 17. Kry SF, Howell RM, Polf JC, Mohan R, Vassiliev ON. Treatment vault shielding for a flattening filter free medical linear accelerator. Phys Med Biol 54(5):1265-1273, 2/2009. 18. Peterson S, Polf JC, Ciangaru G, Bues M, Beddar S, Smith A. Experimental validation of a monte carlo proton therapy nozzle model incorporating magnetically steered protons. Phys Med Biol 54(10):3217-3229, 5/2009. 19. Peterson SW, Polf JC, Ciangaru C, Frank SJ, Bues M, Smith AR. Variations in proton scanned beam dose delivery due to uncertainties in magnetic beam steering. Med. Phys. 36(8):3693-3702, 7/2009. 20. Polf JC, Peterson SW, McCleskey M, Roeder BT, Spiridon A, Beddar S, Trache L. Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation. Phys Med Biol 54(11):N519-N527, 11/2009. 21. Peterson SW, Robertson D, Polf JC, Optimizing a three-stage Compton camera for measuring prompt gamma rays during proton irradiation, Phys Med Biol 55(11):6841-6856, 11/2010. 22. Polf JC, Bronk L, Driessen W, Arap W, Pasqualini, R. Gillin, M., Enahnced Relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles. Appl Phys Letters 98:193702(1-3), 2011. 23. Robertson D, Polf JC, Peterson SW, Gillin M, Beddar S. Material efficiency studies for a Compton camera specifically designed for measuring prompt gamma rays emitted during proton radiotherapy. Phys Med Biol 56:3047-3059, 2011. 24. Wootton L, Polf JC, Peterson S, Wilkinson J, Rozner MA, Balter PA, Beddar S. Proton dose perturbations caused by high-voltage leads from implanted cardioverter defibrillators. J Appl Clin Med Phys. 13(4):13-22, 2012. 25. Mackin D, Peterson SW, Beddar S, Polf JC, Evaluation of a stochastic reconstruction algorithm for use in Compton camera imaging and beam range verification from secondary gamma emission during proton therapy, Phys Med Biol 57:3537-3553, 2012. 26. Mackin D, Polf JC, Peterson SW, Beddar S, Measurement of Doppler broadening and detector resolution effects on the performance of 3-stage Compton cameras, Med Phys, 40(1):012402, 2013. 27. Polf JC, Panthi R, Mackin DS, McCleskey M, Saastamoinen A, Roeder BT and Beddar S, Measurement of characteristic prompt gamma rays emitted from oxygen and carbon in tissueequivalent samples during proton beam irradiation, Phys Med Biol, 58(17):5821-5831, 2013.
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28. Polf JC, Mackin DS, Lee E, Avery S, and Beddar S, Detecting prompt gamma emission during proton therapy: the effects of detector size and distance from the patient, Phys Med Biol, 58:(in press), 2013. 29. Senavirathna, LK, Fernando R, Maples D, Zheng, Y, Polf JC, Ranjan A, Tumor spheroids as an in vitro model for determining the therapeutic response to proton beam radiotherapy and thermally sensitive nanocarriers, Theranostics 3(9):687-691, 2013. Invited Articles (Peer Reviewed) 1.
2.
3.
McKeever SWS, Akselrod MS, Colyott LE, Agersnap-Larsen N, Polf JC, Whitley VH. Optically and Thermally Stimulated Luminscence using Al2O3. I Conferencia International and XI Congresso Nacional sobre Dosimetria de Estado Solido, Puebla Mexico, 1998. Newhauser W, Fontenot J, Zheng Y, Polf J, Titt U, Koch N, Zhang X, Mohan R,. Monte Carlo model of a passively scattered proton therapy system. American Nuclear Society 14th Meeting of the Radiation Protection and Shielding Division 2006:252-255, 6/2006. Polf JC, Peterson SW, Robertson D, and Beddar S, Measuring prompt gamma ray emission during st proton radiotherapy for assessment of treatment delivery and patient response, CAARI: 21 International Conference on the Application of Accelerators in Research and Industry, AIP Conference Proceedings 1336:364-368 2011.
Books and Book Chapters 1. Polf JC, Nicholas Depauw, and .Seco J., Monte Carlo applications in prompt gamma imaging and st proton radiography in proton radiotherapy. In: Monte Carlo Techniques in Radiotherapy, 1 Edition, Imaging in Medical Diagnosis and Therapy Series, CRC Press, Fall 2012. Abstracts (past 5 years) 1. Peterson SW, Polf JC. Characterizing Prompt Gamma Ray Emission from a Proton therapy Treatment Nozzle. AAPM 51st Annual Meeting, Anahiem Ca, 2009. 2. Polf JC, Peterson SW, McKelskey M, Roeder B, Spiridon A, Beddar S, Trache L, Feasibility of Determining Irradiated Tissue Type from Measured Prompt Gamma Spectra Emitted During Proton Therapy. AAPM 51st Annual Meeting, Anaheim Ca, 2009. 3. Polf JC, Peterson SW, and Beddar S, Initial Studies of Prompt Gamma Imaging During Proton Radiotherapy for the Assessment of Tumor and Healthy Tissue Response, ITART, Washington DC, 6/21/2010. 4. Peterson SW, Mackin DS, and Polf JC, Reconstructing images of prompt gammas emitted during proton radiotherapy, AAPM 53rd Annual Meeting, Vancouver BC, 2011. 5. Brown C and Polf JC, Designing a Low Cost Digital Imaging System for Medical Physics Education, th AAPM 55 Annual Meeting, Indianapolis IN, 2013. 6. Lee E, Polf JC, Mackin DS, Dolney D, Beddar S, and Avery S, Patient-Based Study On Characteristic Prompt Gamma-Ray Spectra Using a Prompt Gamma Imaging System During Proton Therapy, th AAPM 55 Annual Meeting, Indianapolis IN, 2013. 7. Polf JC, Polf H, and Rodebush C, How to CT a Horse Using a CT Scanner Built for Human Imaging, th AAPM 55 Annual Meeting, Indianapolis IN, 2013. 8. Mackin DS, Polf JC, Avery S, Lee E, Dolney D, and Beddar S, Characteristics of Prompt Gamma th Compton Interactions in Detectors, AAPM 55 Annual Meeting, Indianapolis IN, 2013. 9. Polf JC, Mackin DS, Lee E, Avery S, Dolney D, Beddar S, Characterizing Prompt Gamma Signal th During Proton Radiotherapy, AAPM 55 Annual Meeting, Indianapolis IN, 2013. 10. Bronk LF, Polf JC, Driessen WHP, Gillin MT, Arap W, Pasqualini R, Nanoscaffold-Enhanced Proton th Therapy, AAPM 55 Annual Meeting, Indianapolis IN, 2013. 11. Polf JC, Development of prompt gamma based in-vivo range verification systems in proton radiotherapy, IEEE NSS MIC conference, Seoul, South Korea, 2013.
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Jerimy C. Polf, Ph.D.
MAJOR INVITED SPEECHES Invited Conference Presentations 1. Polf JC, Biological Imaging in Proton therapy, SWAAPM, Houston, TX, 10/4/2009 2. Polf JC, Peterson SW, Kapadeth C, Monte Carlo Applications in Proton Therapy, International Geant 4 Users Workshop and Collaboration Conference, Geant4 Development Collaboration, Catania, Italy, 10/11/2009 3. Polf JC, Robertson D, and Peterson SW, Prompt gamma ray emission during proton radiotherapy for st assessing treatment delivery and patient response, 21 International Conference on Application of Accelerators in Research and Industry, Dallas TX, 08//19/2010. 4. Polf JC, Using prompt gamma ray emission to address uncertainties in proton therapy, Joint Imagingth Therapy Session: New Technologies Addressing Proton Range Uncertainties, AAPM 55 Annual Meeting, Indianapolis IN, 2013. 5. Polf JC, Development of prompt gamma based in-vivo range verification systems in proton radiotherapy, New Technologies in Hadron Therapy Workshop, IEEE NSS MIC conference, Seoul, South Korea, 2013.
Invited Seminars from Other Institutions 1. Simulations of Real Time Charge Trapping in Al2O3 Fibers, Department of Nuclear Engineering, Risoe National, Roskilde, Denmark, 2/15/2002 2. Fiber Optic Dosimetry System for use in the Measurement of Delivered Doses during Radiotherapy. Department of Radiation Physics, University of Wisconsin, Madison, WI, 8/14/2002 3. Introductory Overview of Proton Beam Radiation Therapy, Oklahoma State University, Department of Physics, Stillwater, OK, 11/3/2005 4. Application of Proton Beams in Radiation Therapy. Industrial Chapter Meeting, Biomedical Engineering Society, Houston, TX, 1/12/2006 5. Overview of Proton Therapy: Clinical Practices and Current Research, Texas A&M University, Cyclotron Institute, College Station, TX, 3/17/2009 6. Prompt gamma ray emission during proton radiotherapy for assessing treatment delivery and patient response, University of Michigan, Department of Nuclear Engineering, Ann Arbor, MI, 01//12/2011. 7. Secondary prompt gamma ray emission during proton radiotherapy: current research activities, Massachusetts General Hospital, Burr Proton Therapy Center, Boston, MA, 12//04/2011. 8. Reconstructing images of prompt gammas emitted during proton radiotherapy, University of Maryland School of Medicine, Division of Radiation Oncology, Baltimore, MD, 05/25/2012. 9. Online beam range verification for proton therapy using prompt gamma imaging, Samsung Medical Center, Department of Radiation Oncology, Seoul, South Korea, 10/29/2013.
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