Curriculum Vitae Mu-Han Lin, Ph.D. Department of Radiation Oncology University of Maryland School of Medicine Date: 12/18/2013 Education B.S. (Medical Imaging and Radiological Science): Chang Gung University, Taiwan, 2003 M.S. (Medical Physics): National Tsing Hua University, Taiwan, 2005 Ph.D. (Medical Physics): National Tsing Hua University, Taiwan, 2010
Post Graduate Education and Training July 2004 – Sep. 2004 Hospital Internship in Therapeutic Radiology, Radiation Oncology, Chang Gung Memorial Hospital, Taiwan July 2008 – Sep. 2008
Practicum in Medical Physics, Department of Radiation Oncology, Columbia University Medical Center (CUMC) of New York-Presbyterian Hospital, NY
March 2010 – Oct. 2010 Visiting Scientist, Department of Radiation Oncology, Fox Chase Cancer Center, PA Nov. 2010 – Nov. 2013 Medical Physics Resident, Department of Radiation Oncology, Fox Chase Cancer Center, PA Certifications The American Board of Radiology (ABR) on Therapeutic Physics Exam: Part 1 (2011) and Part 2 (2013) Employment History Apr. 2005 – Sep. 2005 Oct. 2005 – Aug. 2006
Medical Physicist, Radiation Oncology, Taichung Hospital, Health Department, Executive Yuan, Taiwan Research Assistant, Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taiwan
Nov. 2010 –Nov. 2013 Medical Physics Resident, Department of Radiation Oncology, Fox Chase Cancer Center, PA Nov. 2013 – Present Assistant Professor, Department of Radiation Oncology, University of Maryland School of Medicine, MD Professional Society Memberships Full Member of American Association of Physicists in Medicine (AAPM) Full Member of AAPM Delaware Local Chapter (DVC)
Awards and Honors: 2005 Student Competition Award (1st Place), 1st Symposium on Medical Physics and Imaging Science, Taiwan 2005 Honorary Member of the Phi Tau Phi Scholastic Honor Society of the Republic of China, Taiwan 2006 Abstract of Special Merit, 2006 AAPM Annual Meeting, Orlando 2006 President’s List, National Tsing Hua University, Taiwan 2008 Students’ International Visiting Award, National Tsing Hua University, Taiwan 2009 Scholarship of the Graduate Students Study Abroad Program, National Science Council, Taiwan 2010 Radiation Therapy Scientific Paper Competition Award, Taiwan Clinical Oncology Research Foundation, Taiwan 2011 DVC-AAPM Young Investigators Award (3rd Place), Philadelphia 2012 DVC-AAPM Young Investigators Award (3rd Place), Philadelphia 2012 Best in Physics (Therapy), 2012 AAPM Annual Meeting, Charlotte 2012 ‘Newsworthy’ Topic, 2012 AAPM Annual Meeting, Charlotte 2013 DVC-AAPM Young Investigators Award (1st Place), Philadelphia 2013 Resident Recognition Award (Physics Category), ASTRO Annual Meeting, Atlanta Clinical Activities Stereotactic body radiation therapy - Planning strategies for lung cancer SBRT treatments Patient-specific quality assurance - Implemented EPID-based and 2D-array-based pretreatment QA procedures for both Linac and Cyberknife treatments On-line/off-line patient dose reconstruction and validation - Adopted real-time measured signals to guide 3D and 4D patient dose reconstruction and validate the delivered dose Pulsed low dose rate radiotherapy (PLDR) using IMRT and VMAT for recurrent/reirradiation treatments - Taking the advantages of the tumor hyper-radiosensitivity under low dose and the increased normal tissue repairing under low dose rate to achieve a better therapeutic ratio for the re-irradiation patient treatment
Teaching Services 2003-2009 Teaching Assistant for University and Graduate Program Lectures: (10-30 Student/class, average 3-6 hr/week) Probability and Statistics (Textbook by W. Hines), Radiation Therapy Physics (Textbook by F. M. Khan), Radiation Dosimetry (Textbook by F .K. Attix), Radiation Detection and Measurement (Textbook by G. Knoll), Introduction to Nuclear Science (Textbook by J. Turner), Radiation Physics (Textbook by J. R. Cunningham), Health Physics (Textbook by H. Cember), Medical Radiation Dosimetry
Tasks: 1. Responsible for the review lectures before the midterms/finals. 2. Prepare the questions and answers for the homework and the quiz/exam 3. Weekly office hours for answering the student’s questions retarding the course/homework Department of Biomedical Engineering and Environmental Sciences, Department of Nuclear Science, National Tsing Hua University, Taiwan
2010-2013 Radiation Physics Lecture Series, for physics residents, dosimetrists and Oncology residents (~12 students, 1hr/week, 2 lectures/year) Department of Radiation Oncology, Fox Chase Cancer Center 2011-2013
Instructor for the “Introduction to Monte Carlo Treatment Planning” Course (10-15 attendees, responsible for one lecture and five labs) Department of Radiation Oncology, Fox Chase Cancer Center
Publications Peer-reviewed journal articles 1. M Lin, T.C. Chao, C.C. Lee, C.J. Tung, C.Y. Yeh, J.H. Hong. “ Measurementbased Monte Carlo dose calculation system for IMRT pretreatment and on-line transit dose verifications,” Medal Physics (36), 1167-1175, 2009 2. M Lin, T.C. Chao, C.C.Lee, J. T.C. Chang, C. J. Tung. “ Tissue classifications in Monte Carlo simulations of patient dose for photon beam tumor treatments,” Nucl. Instr. Meth. Phys. Res. A. (619), 393-396, 2010 3. B. Yang, Z. Dong, M Lin, C. Ma, “A new method to deliver supraclavicular radiation in breast radiotherapy for lung sparing”, Journal of Applied Clinical Medical Physics, (12), 169-177, 2011 4. S.W. Wu, T.C. Chao, C.J. Tung, M Lin, C.C. Lee “MLC Mediated Beam Hardening Effects In IMRT”, Radiation Measurements, (46), 1989-1992, 2011 5. C. Ma, M Lin, X. Dai, S. Koren, T. Klayton, L. Wang, J. Li, L. Chen, R.A. Price, “Investigation of pulsed low dose rate radiotherapy using dynamic arc delivery techniques”, Physics in Medicine and Biology (57), 4613-4626, 2012 6. M Lin, J. Li, L. Wang, S. Koren, J. Fan, F. Eugene, C. Ma, “4D Patient Dose Reconstruction Using On-line Measured EPID Cine Images for Lung SBRT Treatment Validation”, Medal Physics (39), 5949-5958, 2012 7. M Lin, K. Koren, I. Veltchev, R.A. Price Jr., C-M Ma, “Measurement comparison and Monte Carlo analysis for volumetric modulated arc therapy
(VMAT) delivery verification using the ArcCHECK dosimetry system”, Journal of Applied Clinical Medical Physics (14, No.2), 220-233, 2013 8. M Lin, J. Li, R.A. Price Jr., L. Wang, C.C. Lee, C. Ma, “Dosimetric Impact of Dental Implants on Dose Calculation of Volumetric Modulated Arc Therapy for Head-and-neck Treatment”, Physics in Medicine and Biology (58), 1027-1040, 2013 9. J. S. Li, M Lin, M. K. Buyyounouski, E. M. Horwitz, C-M. Ma, “Reduction of prostate intrafractional motion from shortening the treatment time”, Physics in Medicine and Biology (58), 4921-4912, 2013 10. E. Fourkal, I. Veltchev, M Lin, S. Koren, J. Mayer, M. Doss, J.Q. Yu, “3D inpatient dose reconstruction from the PET-CT imaging of Y-90 microspheres for metastatic cancer to the liver: Feasibility study”, Medical Physics (40), 081702, 2013 11. L. Wang, X. Chen, M Lin, J. Xue, T. Lin, J. Fan, C. Ma, “ Evaluation of the cone beam CT for internal target volume localization in lung stereotactic radiotherapy in comparison with 4D MIP images”, Medical Physics, (40), 111709, 2013 12. M Lin, R. A. Price, J. S. Li, S. Kang, J. Li, C. Ma, “Investigation of Pulsed IMRT and VMAT for Re-irradiation Treatments: Dosimetric and Delivery Feasibilities”, Physics in Medicine and Biology, (58), 8179‐8196, 2013 13. C. Y. Yeh, C. C. Lee, T. C. Chao, M Lin, P. A. Lai, F. H. Liu, C. J. Yung, “Application of the measurement-based Monte Carlo method in nasopharyngeal cancer patients for intensity modulated radiation therapy”, Radiation Physics and Chemistry, (95), 240-242, 2014 14. R. A. Price Jr., S. Koren, I. Veltchev, M. Hossain, M Lin, T. Galloway, P. Flanagan, J. Haber, C-M. Ma, “Planning target volume-to-skin proximity for head-and-neck intensity modulated radiation therapy treatment planning”, Practical Radiation Oncology, (2013, In Press) 15. C.Y. Yeh, C.J. Tung, T.C. Chao, M. Lin, C. Lee, "A dual resolution measurement based Monte Carlo simulation technique for detail dose analysis of small volume organs in the skull base region", Radiation Physics and Chemistry, (2013, In Press) Abstracts and/or Proceedings 1. CC Lee, TC Chao, YF Lin, M Lin, CJ Tung. “ An on‐line patient dose verification system for IMRT ,” posted paper presented at the 46th Annual Meeting of AAPM, Pittsburgh, July 25‐29, 2004 2. M Lin, CC Lee, TC Chao, CJ Tung. “Dosimetric properties of an amorphous silicon electronic portal imaging device,” poster paper presented at the 2nd Annual Meeting of the Chinese Society of Medical Physics, Kao‐Hsiung, March 26‐27, 2005. 3. M Lin, CC Lee, TC Chao, CJ Tung. “Transit dosimetry comparison between EPID measurement and Monte Carlo simulation for IMRT,” oral paper presented at the 2nd Annual Meeting of the Chinese Society of Medical Physics, Kao‐Hsiung, Mar. 26‐27, 2005.
4. M Lin, CC Lee, TC Chao, CJ Tung. “An on‐line patient dose verification system for IMRT,” oral paper presented at the 1st Symposium on Medical Physics and Imaging Science, Hsingchu, Taiwan, May 21, 2005. 5. M Lin, CC Lee, TC Chao, CJ Tung. “Pixel‐based dead time correction for aS500 EPID,” posted paper presented at 47th Annual Meeting of AAPM, Seattle, July 24‐28, 2005. 6. M Lin, CC Lee, TC Chao. “Fast absolute dose calculation using Monte Carlo methods for IMRT,” oral paper presented at the 3rd Annual Meeting of the Chinese Society of Medical Physics, Kao‐Hsiung, Mar. 25‐26, 2006. 7. CC Lee, M Lin, TC Chao, CJ Tung. “Simplified Monte Carlo simulation for absolute dose distribution of IMRT,” posted paper presented at 48th Annual Meeting of AAPM, Orlando, July 30‐Aug. 3, 2006. 8. M Lin, CC Lee, TC Chao, CJ Tung. “Dose Response of Spectral Change of AS1000 EPID,” posted paper presented at 50th AAPM, Houston, July 27 ‐ 31, 2008. 9. M Lin, CJ Tung, CC Lee, TC Chao, “Tissue classifications in Monte Carlo simulations of patient dose for photon beam tumor treatments,” posted paper presented at 11th International Symposium on Radiation Physics (ISRP‐11), Australia ,Sep. 20‐25, 2009 10. M Lin, CJ Tung, CC Lee, TC Chao, Joseph Tung‐Chieh Chang, “Measurement‐ based Monte Carlo patient dose calculation for head and neck cancer treatment,” posted paper presented at 11th International Symposium on Radiation Physics (ISRP‐11), Australia ,Sep. 20‐25, 2009 11. M Lin, CC Lee, J Li, L Wang, C‐M Ma, TC Chao, CJ Tung. “Clinical implementation of Monte Carlo simulation for RapidArc dosimetry verification” posted paper presented at 52nd Annual meeting of AAPM, Philadelphia, July 18 ‐ 22, 2010. 12. M Lin, J Li, S Koren, T Lin, L Wang, C‐M Ma. “A practical Monte Carlo based patient dose verification tool for RapidArc treatment” posted paper presented at 52nd Annual Meeting of ASTRO, San Diego, Oct.31‐Nov.04, 2010 13. M Lin, J Li, L Wang, CC Lee, TC Chao, CJ Tung, C‐M Charlie Ma. “ The impact of metal artifact on head and neck RapidArc treatment plan optimization and dose calculation‐ a Monte Carlo study” oral paper presented at 10th Asia‐ Oceania Congress of Medical Physics (AOCMP), Taipei, Taiwan, Oct. 15‐17, 2010 14. C Ma, M Lin, L Wang, R Price, “ Dosimetric Evaluation for Pulsed Low Dose Rate Radiation Therapy Using RapidArc Delivery Techniques”, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011 15. E Fourkal, I Veltchev, M Lin, C Ma, “Tissue Inhomogeneity in Hadron Therapy”, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011 16. J Xue, H Liu, X Chen, M Lin, Z Dong, L Wang, L Chen, C Ma, “ Image‐Guided Radiation Therapy: The Accuracy of CT‐MR Fusion for Prostate Treatment Planning”, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011
17. S Koren, M Lin, I Veltchev, C Ma, “Measurement Comparison and Monte Carlo Analysis for Rapid Arc Delivery Verification Using ArcCheck Dosimetry System”, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011 18. H Liu, J Xue, X Chen, M Lin, S Koren, Z Dong, L Chen, C Ma, “An End‐To‐End Quality Assurance Procedure for Advanced Radiation Therapy”, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011 19. J Li, M Lin, L Wang, C. Ma, “ Dosimetric Uncertainties in RapidArc Treatment“, posted paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011 20. M Lin, J. Li, L. Wang, C. Ma, “EPID‐Based 4D Patient Dose Verification for Lung SBRT Treatment”, oral paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011. 21. M Lin, A. G. Tafo, J. Li, E. Fourkal, C. Ma, “Respiratory Motion Effects On Lung Proton SBRT Treatment”, oral paper presented at 53rd Annual meeting of AAPM, Vancouver, July 31‐ Aug. 4, 2011. 22. M Lin, J. Li, J.E. Mayer, C. Ma, “ Pulsed Low Dose Rate Radiation Therapy Using Intensity Modulated Radiotherapy”, oral paper presented at 97th Annual Meeting of RSNA, Chicago, Nov. 27 – Dec. 2, 2011 23. G Yin, S Koren, M Lin, L Chen, C Ma, “ Dosimetric Evaluation of Different Treatment Techniques for Prostate Cancer”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 24. J Xue, X Chen, L Chen, Q Xu, Z Dong, M Lin, L Wang, C Ma, “Prostate IGRT: CT‐ MRI Fusion and Target Delineation Accuracy”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 25. Q Xu, Mu‐Han Lin, X Chen, X Tong, J Fan, Z dong, L Chen, C Ma, “Feasibility of Using EPID for Real‐Time Target Localization During Treatment”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 26. S Koren, R Price, I Veltchev, M Lin, J Fan, C Ma, “3D Dose Measurements Using the Planned Dose Perturbation Technique (PDP) for the Evaluation of Head and Neck VMAT Treatment”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 27. J Li, Mu‐Han Lin, C‐M Ma, “Impact of the Treatment Margin On Tumor Control and Normal Tissue Complication for Prostate Treatment”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 28. X Tong, X Chen, J Li, M Lin, L Chen, Q Xu, C Ma, „“Investigation of Prostate Intrafractional Motion During External Beam Radiotherapy for a Large Patient Population”, oral paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 29. S Koren, I Veltchev, J Fan, M Lin, A G Tafo, C M, “CyberKnife Patient Specific QA Using a 4D Cylindrical Diode Array System”, oral paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 30. E Fourkal, I Veltchev, S Koren, M Lin, C Ma, J Meyer, M Doss, M Yu, “3D In‐ Patient Dose Reconstruction From the PET‐CT Imaging of Y‐90 Microspheres
for Metastatic Cancer to the Liver”, oral paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 31. M Lin, J. Li, J. Fan, T. Lin, C. Ma, “Dosimetric Impact of Respiratory Motion for Proton SBRT”, oral paper presented at World Congress on Medical Physics and Biomedical Engineering, Beijing, May 26‐ 31, 2012 32. M Lin, J. Li, S. Koren, R.A. Price, C. Ma, “Pulsed Low Dose Rate Radiotherapy using Advanced Treatment Methods: A Novel Technique for Patient Re‐ irradiation”, posted paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 33. M Lin, J. Li, S. Koren, L. Wang, J. Fan, Y. Gang, C. Ma, “Development and Experimental Validation of EPID‐based 4D Dose Reconstruction”, oral paper presented at 54th Annual meeting of AAPM, Charlotte, July 29‐ Aug. 2, 2012 34. M Lin, J. Li, L. Wang, E. Forkal, R. Price, J. Fan, C. Ma, “Investigation of the Planning Strategy with Dual‐Algorithm for Small Lesions in the Heterogeneous Region” poster paper presented at 55th Annual meeting of AAPM, Indianapolis, Aug. 4‐ 8, 2013 35. M Lin, I. Veltchev, J. Li, R. Price, J. Fan, L. Jin, S. Koren, C. Ma, “Evaluation of the Planar Ion Chamber and the Cylindrical Diode Arrays for Extracranial Cyberknife Patient Specific QA” oral paper presented at 55th Annual meeting of AAPM, Indianapolis, Aug. 4‐ 8, 2013 36. M Lin, J. Li, C. Ma, “ Clinical Implementation of a Comprehensive EPID‐Based 3D/4D Patient Dose Reconstruction Framework for Complex Treatment Validations ”, Electronic poster discussion presented at 55th ASTRO Annual meeting, Atlanta, Sep. 22 –25, 2013 37. L. Wang, J. Uzan, C. Baker, M. Lin, S. Hayes, J. Meyer, C.M. Ma, A.E. Nahum, “Towards individualized dose prescription for hypofractionation in liver cancer radiotherapy”, oral paper, ESTRO 33, Vienna, Austria, Apr. 4‐8, 2014