CURRICULUM VITAE Vladimir Yurovsky, Ph.D. Assistant Professor of Neurosurgery University of Maryland School of Medicine August 2005 Personal Information Business Address: MSTF Room 6-30, 10 South Pine Street, Baltimore, MD 21201 Business Phone: (410) 706-1769 Fax: (410) 706-0333 E-mail: vyurovsk@umaryland.edu Education 1975-80 Moscow State University, Moscow, U.S.S.R. 1980-83 M.M. Shemyakin Institute of Bioorganic Chemistry, Moscow, U.S.S.R. 1989 Scientific-Research Center for Transplantology & Artificial Organs, Moscow, U.S.S.R.
M.S. Major: Biochemistry M.S. Major: Bioorganic Chemistry Ph.D. Special Field: Transplantology
Post Graduate Education and Training 1990-95 University of Maryland School of Medicine, Baltimore, MD
Postdoctoral Fellowship
Employment History 1983-88 Junior Research Fellow, Branch of M.M. Shemyakin Institute of Bioorganic Chemistry, Pushchino, Moscow Region, Russia 1988-90 Senior Research Fellow, Scientific-Industrial Association “Biotechnologia�, Moscow, Russia 1996-97 Clinical Instructor, University of Maryland School of Medicine, Baltimore, MD 1997-present Assistant Professor, University of Maryland School of Medicine, Baltimore, MD 1999-2002 Associate Investigator, Veterans Administration Maryland Health Care System, Baltimore, MD Honors and Awards 1993, 1994 Trainee Investigator Award, American Federation for Clinical Research 1996, 1998 Travel Award, American College of Rheumatology Research & Education Foundation 2000 Travel Award, U.S. Civilian Research & Development Foundation 2001, 2002 Junior Faculty Award, American Association of Immunologists 2002, 2003 Investigator Travel Award, American Federation for Medical Research Teaching Service 1998 Mentoring research student Carolyn Bose 2003 Mentoring research scholar Alexey Garkovenko Grant Support Past Co-Investigator 1/1/94-12/31/94
Scleroderma Federation/United Scleroderma Foundation. Diversity of CD8+ T cells in the lungs of systemic sclerosis patients with active alveolitis
Principal Investigator 1/1/95-12/31/95
Scleroderma Federation/United Scleroderma Foundation. Function of oligoclonal CD8+ T cells in scleroderma patients
Principal Investigator 7/1/95-6/30/98
Arthritis Foundation Fellowship. Effector functions of oligoclonal T cells from lungs of scleroderma patients
Principal Investigator 7/1/98-6/30/99
University of Maryland School of Medicine Intramural Grant. Antigen specificity of clonally expanded T cells in the lungs of systemic sclerosis patients
Principal Investigator 1/1/97-12/31/99
Arthritis Foundation. Arthritis Investigator Award. Role of T cells in a model of scleroderma lung disease
Principal Investigator 4/1/99-9/30/02
Veterans Administration Type II Merit Review Award. T cells mediating fibrosis in human lungs
Principal Investigator 1/15/03-12/31/04
Scleroderma Foundation Role of TRAIL in pulmonary fibrosis in scleroderma
Current Principal Investigator 7/1/05-6/30/07
American Heart Association Role of TGFbeta in NO-tolerance following subarachnoid hemorrhage
Publications Refereed Articles 1. Yurovsky VV, Vasilov RG. The use of monoclonal antibodies for isolation and characterization of murine histocompatibility antigens. Biol Membranes 1:1465-85, 1985. 2. Yurovsky VV, Safonova NG, Khaidukov SV, Vasilov RG, Demin VV. Synthesis and immunochemical study of an antigenic determinant of H-2Db molecule of murine major histocompatibility complex. Soviet J Bioorg Chem 12:29-37, 1986. 3. Yurovsky VV, Bovin NV, Safonova NG, Vasilov RG, Khorlin AYa. Artificial peptide and carbohydrate antigens. Immobilization of haptens and adjuvant (MDP) on polyacrylamide. Soviet J Bioorg Chem 12:38-42, 1986. 4. Allakhverdiev AM, Yurovsky VV. Study of protein biosynthesis in the culture of malaria causative agent P. falciparum in a putative quiescent state. Meditsinskaya Parazitologia i Parazitarnye Bolezni 4:10-13, 1988 (in Russian). 5. Rar VA, Makarov EA, Yurovsky VV, Meshcheryakova EA, Andronova TM, Ivanov VT. Synthetic immunogenic complexes based on a peptide of the surface protein of the foot-and-mouth disease virus. Soviet J Bioorg Chem 16:519-29, 1990. 6. Ivanov BB, Yurovsky VV, Tertyshnikova SM, Andronova TM, Ivanov VT. Synthesis of peptides forming fragments of the proteins of Plasmodium falciparum and their conjugates with proteins and synthetic carriers. Soviet J Bioorg Chem 17:276-82, 1991. 7. Tertyshnikova SM, Yurovsky VV, Ivanov BB, Sadovnikov VB, Allakhverdiev AM. Immunochemical study of antigenic determinants of the surface proteins of the causative agent of tropical malaria parasite Plasmodium falciparum with the aid of synthetic peptides. Soviet J Bioorg Chem 17:283-91, 1991. 8. Yurovsky VV, Kelsoe G. Pairing of VH gene families with the 1 light chain: evidence for a non-stochastic association. Eur J Immunol 23:1975-9, 1993. 9. Yurovsky VV, Sutton PA, Schulze DH, Wigley FM, Wise RA, Howard RF, White B. Expansion of selected V 1+ / T cells in systemic sclerosis patients. J Immunol 153:881-91, 1994.
10. Yurovsky VV, Schulze DH, White B. Analysis of diversity of T cell antigen receptor genes using polymerase chain reaction and sequencing gel electrophoresis. J Immunol Methods 175:227-36, 1994. 11. Atamas SP, Choi J, Yurovsky VV, White B. An alternative splice variant of human interleukin-4, IL-4 2, inhibits interleukin-4 stimulated T cell proliferation. J Immunol 156:435-41, 1996. 12. Alms WJ, Atamas SP, Yurovsky VV, White B. Generation of a variant of human interleukin-4 by alternative splicing. Mol Immunol 33:361-70, 1996. 13. Alms WJ, Braun-Elvert L, James SP, Yurovsky VV, White B. Simultaneous quantitation of cytokine mRNAs by reverse transcription-polymerase chain reaction using multiple internal standard cRNAs. Diagnostic Molec Pathol 5:88-97, 1996. 14. Yurovsky VV, Wigley FM, Wise RA, White B. Skewing of the CD8+ T-cell repertoire in the lungs of patients with systemic sclerosis. Hum Immunol 48:84-97, 1996. 15. Yurovsky VV, Bleecker ER, White B. Restricted T-cell antigen receptor repertoire in bronchoalveolar T cells from normal humans. Hum Immunol 50:22-37, 1996. 16. Tsytsikov VN, Yurovsky VV, Atamas SP, Alms WJ, White B. Identification and characterization of two alternative splice variants of human interleukin-2. J Biol Chem 271:23055-60, 1996. 17. Zav’yalov VP, Denesyuk AI, White B, Yurovsky VV, Atamas SP, Korpela T. Molecular model of an alternative splice variant of human IL-4, IL-4 2, a naturally occurring inhibitor of IL-4-stimulated T cell proliferation. Immunol Lett 58:149-52, 1997. 18. Serebruany VL, Ordonez JV, Yurovsky VV, Gurbel PA. The crossreactivity of human vs swine platelet surface antigens: similarity of glycoproteins Ib and IIIa, but not IIb/IIIa complex. J Thromb Thrombolysis 5:37-41, 1998. 19. Yurovsky VV, Weersink EJM, Meltzer SS, Moore WC, Postma DS, Bleecker ER, White B. T cell repertoire in the blood and lungs of atopic asthmatics before and after ragweed challenge. Am J Respir Cell Mol Biol 18:370-83, 1998. 20. Atamas SP, Yurovsky VV, Wise R, Wigley FM, Goter Robinson CJ, Henry P, Alms WJ, White B. Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis. Arthritis Rheum 42:1168-78, 1999. 21. Serebruany VL, Yurovsky VV, Gurbel PA. Mild myocardial stunning affects platelet aggregation and certain hemostatic factors in swine. Clin Appl Trombosis/Hemostasis 5:236-42, 1999. 22. Serebruany VL, Yurovsky VV, Gurbel PA. Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction. Life Sci 65:1503-13, 1999. 23. Henry PA, Atamas SP, Yurovsky VV, Luzina I, Wigley FM, White B. Diversity and plasticity of the antiDNA topoisomerase I autoantibody response in scleroderma. Arthritis Rheum 43:2733-42, 2000. 24. Yurovsky VV, Cottler-Fox MH, Atamas SP, Shanholtz CB, Britt EJ, Sensenbrenner LL, White B. Pulmonary T cell repertoire in patients with graft-versus-host disease following blood and marrow transplantation. Am J Hematol 66:1-11, 2001. 25. Yurovsky VV. Advances in prevention and treatment of graft versus host disease. Expert Opin Ther Patents 12:1385-93, 2002. 26. Yurovsky VV. Tumor necrosis factor-related apoptosis-inducing ligand enhances collagen production by human lung fibroblasts. Am J Respir Cell Mol Biol 28:225-31, 2003. 27. Navolotskaya EV, Zargarova TA, Malkova NV, Zharmukhamedova TYu, Kolobov AA, Kampe-Nemm EA, Yurovsky VV, Lipkin VM. Macrophage-stimulating peptides VKGFY and cyclo(VKGFY) act through nonopioid -endorphin receptors. Biochem Biophys Res Commun 303:1065-72, 2003. 28. Yurovsky VV. New insights into the treatment of pulmonary fibrosis. Expert Opin Ther Patents 13:957-67, 2003. 29. Navolotskaya EV, Kovalitskaya YuA, Zolotarev YuA, Kudryashova NYu, Goncharenko EN, Kolobov AA, Kampe-Nemm EA, Malkova NV, Yurovsky VV, Lipkin VM. -Endorphin-like peptide SLTCLVKGFY
30. 31. 32.
33.
reduces the production of 11-oxycorticosteroids by rat adrenal cortex through nonopioid -endorphin receptors. Peptides 24:1941-6, 2003. Navolotskaya EV, Kovalitskaya YuA, Zolotarev YuA, Kolobov AA, Kampe-Nemm EA, Malkova NV, Yurovsky VV, Lipkin VM. Characteristics of non-opioid -endorphin receptor. Biochemistry (Moscow) 69:488-96, 2004. Navolotskaya EV, Vanina VI, Zolotarev YuA, Kudryashova NYu, Goncharenko EN, Kolobov AA, KampeNemm EA, Yurovsky VV, Lipkin VM. Synthetic peptide immunocortin stimulates the production of 11oxycorticosteroides by rat adrenal cortex through ACTH receptors. Regul Pept 119:99-104, 2004. Navolotskaya EV, Vanina VI, Zargarova TA, Goncharenko EN, Kudryashova NYu, Akhalaya MYa, Sadovnikov VB, Semushina SG, Kolobov AA, Kampe-Nemm EA, Yurovsky VV, Lipkin VM. An ACTH-like peptide immunocortin: effect on the activity of cells from the rat adrenal cortex. Rus J Bioorg Chem 30:315-9, 2004. Navolotskaya EV, Kovalitskaya YuA, Zolotarev YuA, Kudryashova NYu, Goncharenko EN, Kolobov AA, Kampe-Nemm EA, Malkova NV, Yurovsky VV, Lipkin VM. Elucidation and characteristic of non-opioid endorphin receptors in rat adrenal cortex. Biochemistry (Moscow) 69:870-5, 2004.
Non-Refereed Articles 1. Yurovsky VV, White B. T cell repertoire in systemic sclerosis. Intl Rev Immunol 12:97-105, 1995. 2. White B, Yurovsky VV. Oligoclonal expansion of V 1+ / T cells in systemic sclerosis patients. Ann NY Acad Sci 756:382-91, 1995. 3. Yurovsky VV. The repertoire of T cell receptors in systemic sclerosis. Crit Rev Immunol 15:155-65, 1995. 4. Yurovsky VV, White B, Atamas SP. T cells mediating lung disease in systemic sclerosis. 10th Int Congress of Immunol, New Delhi 1998, pp. 1185-90. 5. Yurovsky VV. Cross-talk between the TRAIL and TGF pathways in regulation of collagen production by lung fibroblasts. 12th Int Congress of Immunol, Montreal 2004, pp. 325-9. Abstracts 1. Yurovsky VV. Isolation and immunochemical characterization of murine histocompatibility antigens. In: The 2nd USSR Symposium on Chemistry of Proteins and Peptides, Riga, USSR. Proceedings, 1982 (in Russian). 2. Vasilov RG, Vturina IYu, Rudenko NV, Trifonov VD, Yurovsky VV. Use of monoclonal antibodies for structural-functional studies of membranous proteins. In: The 3rd Soviet-Swiss Symposium "Biological Membranes: Structure and Functions", Tashkent, USSR. Proceedings, 1983. 3. Deigin VI, Makarov EA, Rar VA, Yurovsky VV. Design and synthesis of an antigenic determinant of footand-mouth disease virus. In: The 9th American Peptide Congress, Toronto, Canada. Proceedings, 1986. 4. Ivanov BB, Makarov EA, Yurovsky VV, Sadovnikov VB, Andronova TM. Synthesis and immunochemical study on synthetic peptides from proteins of the malaria parasite Plasmodium falciparum. In: The 8th USSR Symposium on Chemistry of Proteins and Peptides, Tallin, USSR. Proceedings, p. 181, 1987 (in Russian). 5. Yurovsky VV, Tertyshnikova SM, Okuneva TO, Ivanov BB, Makarov EA, Allakhverdiev AM. In: The 5th Conference of Young Scientists of the Socialist Countries on Bioorganic Chemistry, Pushchino, USSR. Proceedings, p. 73, 1987. 6. Ivanov BB, Yurovsky VV, Okuneva TO, Grinberg LN, Allakhverdiev AM. A study of the immunodominant epitope of the malaria parasite surface protein with help of synthetic peptides. In: International Symposium “Structure and Function of the Immune System Elements�, Pushchino, USSR. Proceedings, p. 94, 1987. 7. Ivanov BB, Andronova TM, Makarov EA, Yurovsky VV, Sadovnikov VB. Synthesis of peptide antigens of the proteins from malaria parasite Plasmodium falciparum. In: The 6th Bilateral USSR-FRG Symposium on Chemistry of Protein and Peptides, Hamburg, Germany. Proceedings, p. 113, 1987.
8. Ivanov VT, Andronova TM, Rar VA, Ivanov BB, Makarov EA, Meshcheryakova EA, Yurovsky VV. Immunogenic complexes made of a peptide antigen, glycopeptide adjuvant and high molecular carrier. J Cell Biochem 12B:35, 1988. 9. Yurovsky VV, Tertyshnikova SM, Ivanov BB. In: The 1st USSR Immunological Congress, Sochi, USSR. Proceedings 1:184, 1989 (in Russian). 10. Yurovsky VV. Structural-functional study of the murine histocompatibility antigen, H-2Db . In: The 19th Conference of the Federation of European Biochemical Societies, Rome, Italy. Proceedings, 1989. 11. Needleman BW, Yurovsky V, Choi J. Regulation of fibroblast activities by CD4+ and CD8+ T cell clones. Arthritis Rheum 35:S312, 1992. 12. Yurovsky VV, Wigley FM, Wise RA, White B. Evidence for oligoclonality of V 1+ T cell antigen receptor transcripts in scleroderma patients. Clin Res 41:244A, 1993. 13. Alms WJ, Yurovsky VV, White B. Characterization of an alternative splice variant of human interleukin 4 (IL4). Clin Res 41:245A, 1993. 14. Yurovsky VV, Wigley FM, Wise RA, White B. Evidence for oligoclonality of V 1+ T cell antigen receptor transcripts in scleroderma patients. J Immunol 150:73A, 1993. 15. Alms WJ, Yurovsky VV, White B. Characterization of an alternative splice variant of human interleukin 4 (IL4). J Immunol 150:247A, 1993. 16. Yurovsky VV, Schulze DH, White B. Use of polymerase chain reaction and sequencing gel electrophoresis for analysis of diversity of T cell receptor genes. Clin Res 41:618A, 1993. 17. Yurovsky VV, Sutton PA, Schulze DH, Wigley FM, Wise RA, White B. Selected expansion of V 1+ / T cells in scleroderma patients. Arthritis Rheum 36:S50, 1993. 18. Alms WJ, Yurovsky VV, White B. Characterization of an alternative splice variant of human interleukin 4 (IL4). Arthritis Rheum 36:S111, 1993. 19. Yurovsky VV, White B. Oligoclonal expansion of V 1+ / T cells in multiple tissues of systemic sclerosis patients. Clin Res 42:142A, 1994. 20. Yurovsky VV, Bleecker ER, White B. Evidence for clonal expansion of bronchoalveolar T cells in normal humans. Clin Res 42:460A, 1994. 21. Yurovsky VV, Wigley FM, Wise RA, White B. Restricted bronchoalveolar T cell repertoire in systemic sclerosis patients. Arthritis Rheum 37:S360, 1994. 22. Weersink EJM, Yurovsky VV, Meltzer SS, Postma DS, Bleecker ER, White B. Expression of V and V repertoire of the T-cell receptor (TCR) in atopic asthmatics after ragweed challenge. Am J Resp Crit Care Med 151:A779, 1995. 23. Atamas SP, Yurovsky VV, White B. Functional studies of human IL-4 2, an alternative splice variant of interleukin-4. In: The 9th International Congress of Immunology, San Francisco, CA. Abstracts, p. 80, 1995. 24. Yurovsky VV, Wigley FM, Wise RA, White B. Bronchoalveolar T cell repertoire in systemic sclerosis patients. In: The 9th International Congress of Immunology, San Francisco, CA. Abstracts, p. 835, 1995. 25. Weersink EJM, Yurovsky VV, Meltzer SS, Postma DS, Bleecker ER, White B. Ragweed-induced changes in the T cell repertoire in blood and bronchoalveolar lavage (BAL) T cells in atopic asthmatics. Eur Respir J 8, Suppl 19:551s, 1995. 26. Yurovsky VV, Wigley FM, Wise RA, White B. T cell repertoire in the lungs of patients with systemic sclerosis. Arthritis Rheum 38:S253, 1995. 27. Yurovsky VV, Weersink EJM, Postma DS, Bleecker ER, White B. T cell repertoire in asthmatic airways before and after ragweed challenge. FASEB J 10:A640, 1996. 28. Tsytsikov VN, Yurovsky VV, Atamas SP, White B. Characterization of alternative splice variants of human interleukin-2. FASEB J 10:A1051, 1996. 29. Yurovsky VV, Weersink EJM, Postma DS, Bleecker ER, White B. T cell repertoire in asthmatic airways following exposure to allergen. FASEB J 10:A1316, 1996.
30. Tsytsikov VN, Yurovsky VV, Atamas SP, White B. Identification and characterization of two alternative splice variants of human interleukin-2 (IL-2) that inhibit function of wildtype IL-2. Arthritis Rheum 39:S128, 1996. 31. Atamas S, Alms W, Yurovsky V, Wise R, Bleecker E, Wigley F, White B. Production of Tc2 cytokines in the lungs of systemic sclerosis (SSc) patients with alveolitis. Arthritis Rheum 39:S232, 1996. 32. Yurovsky VV, Atamas SP, White B. Bronchoalveolar CD8+ T cell clones from systemic sclerosis patient. J Allergy Clin Immunol 99:S182, 1997. 33. Yurovsky VV, Atamas SP, Goter Robinson C, White B. Cloning and characterization of CD8+ T cells from the lungs of systemic sclerosis patients. J Invest Med 45:243A, 1997. 34. Tsytsikov VN, Yurovsky VV, Atamas SP, White B. Characterization of two alternative splice variants of human interleukin-2 (IL-2) that inhibit function of wildtype IL-2. In: Arthritis Research Conference, Bethesda, MD. Abstracts, p. 110, 1997. 35. Atamas SP, Alms W, Yurovsky VV, White B. Tc2 cytokine patterns in the lungs of systemic sclerosis (SSc) patients with alveolitis. In: Arthritis Research Conference, Bethesda, MD. Abstracts, p. 141, 1997. 36. Yurovsky VV, Atamas SP, White B. CD8+ T cell clones from the lungs of systemic sclerosis patient. In: Arthritis Research Conference, Bethesda, MD. Abstracts, p. 141, 1997. 37. Atamas SP, Yurovsky VV, Wigley FM, Wise R, Bleecker E, White B. Complete and alternatively spliced mRNA for interleukin-4 in pulmonary lymphocytes: systemic sclerosis alveolitis versus asthma. Arthritis Rheum 40:S39, 1997. 38. Yurovsky VV, Atamas SP, White B. Functions of clonally expanded CD8+ T cells from the lungs of systemic sclerosis patients with alveolitis. Arthritis Rheum 40:S200, 1997. 39. Yurovsky VV, Atamas SP, White B. Cytotoxic T cells in scleroderma lung disease. Clin Exp Rheumatol 16:198, 1998. 40. Yurovsky VV, Atamas SP, White B. Cytotoxic T cell clones from the lungs of systemic sclerosis patients with alveolitis. FASEB J 12:A1095, 1998. 41. White B, Yurovsky V, Atamas S, Goter Robinson C, Moldovan N, Goldschmidt-Clermont P, Wigley F, Wise R. Immune abnormalities in the lungs of scleroderma patients with alveolitis. Clin Exp Rheumatol 16:363, 1998. 42. Atamas SP, Goter Robinson CJ, Yurovsky VV, White B. CD40 ligation synergizes with IL-4 and IL-4 2 in the induction of collagen and interleukin-6 production by human fibroblasts. In: 5th International Workshop on Scleroderma Research, Boston, MA. Abstracts, p. 2, 1998. 43. Yurovsky VV, Atamas SP, Wigley FM, Wise RA, White B. Alveolar T cell subsets involved in scleroderma lung disease. In: 5th International Workshop on Scleroderma Research, Boston, MA. Abstracts, p. 30, 1998. 44. Yurovsky VV, White B, Atamas SP. T cells mediating lung disease in systemic sclerosis. The Immunologist, Suppl 1:75, 1998. 45. Yurovsky VV, Atamas SP, Wise RA, Wigley FM, White B. Functional activities of T cells involved in scleroderma lung disease. Arthritis Rheum 41:S277, 1998. 46. Tsytsikov VN, Yurovsky VV, Atamas SP, White B. Functional studies of human IL-2 2 and IL-2 3, alternative splice variants of interleukin-2. Arthritis Rheum 41:S351, 1998. 47. Atamas SP, Yurovsky VV, Xiao HQ, Wise RA, Wigley FM, White B. Type 2 cytokines made by CD8+ lung cells predict decline in pulmonary function in patients with systemic sclerosis (SSc). Arthritis Rheum 41:S363, 1998. 48. Yurovsky VV, Cottler-Fox MH, Sensenbrenner LL, White B. T cell repertoire in the lungs of patients with noninfectious pulmonary inflammation following stem cell transplantation. Scand J Immunol 49:340, 1999. 49. Yurovsky VV, White B, Cottler-Fox MH, Sensenbrenner LL. Pulmonary T cell repertoire in patients with GVHD as a model of autoimmune lung disease. J Autoimmun, Suppl: Abstr of 2nd Int Congress on Autoimmunity, Tel Aviv, Israel, p. 124, 1999. 50. Yurovsky VV, Cottler-Fox MH, White B. Bronchoalveolar T cell repertoire in patients with noninfectious pulmonary inflammation following blood and marrow transplantation. J Invest Med 47:216A, 1999.
51. Yurovsky VV, Cottler-Fox MH, White B. Bronchoalveolar T cell repertoire in patients with noninfectious pulmonary inflammation following blood and marrow transplantation. FASEB J 13:A644, 1999. 52. Yurovsky VV, Cottler-Fox MH, White B. Bronchoalveolar T cell repertoire in patients with noninfectious pulmonary inflammation following stem cell transplantation. In: Arthritis Research Conference, Alexandria, VA. Abstracts, p. 42, 1999. 53. Yurovsky VV, Wise R, Wigley F, White B. Pro-fibrotic CD8+ T cells in scleroderma lung disease. Arthritis Rheum 42:S62, 1999. 54. Yurovsky VV, Wigley F, Wise R, White B. Role of T cell and fibroblast interactions in scleroderma lung disease. FASEB J 14:A983, 2000. 55. Yurovsky VV, White B. Effects of type 2 CD8+ T cells on fibroblasts in scleroderma lung disease. Ann Rheum Dis 59, Suppl 1:50-51, 2000. 56. Yurovsky VV, White B. Role of CD154-CD40 interactions in collagen production by fibroblasts. Arthritis Rheum 43:S78, 2000. 57. Yurovsky VV, White B. Effect of CD154-CD40 interactions on collagen production by fibroblasts. Arthritis Res 3:A22, 2001. 58. Yurovsky VV. Effect of TRAIL on collagen production by human lung fibroblasts. J Invest Med 49:251A, 2001. 59. Yurovsky VV. Effect of TRAIL on collagen production by human lung fibroblasts. FASEB J 15:A1045, 2001. 60. Yurovsky VV. Increased collagen production by human lung fibroblasts in the response to tumor necrosis factor-related apoptosis-inducing ligand. Ann Rheum Dis 60, Suppl 1:93, 2001. 61. Yurovsky V, White B. Interactions of T cells and fibroblasts in scleroderma lung disease. Scand J Immunol 54, Suppl 1:43, 2001. 62. Yurovsky V. TNF-related apoptosis-inducing ligand enhances collagen production by human lung fibroblasts. Autoimmunity Rev, Abstr of 3rd Int Congress on Autoimmunity 1:80, 2002. 63. Yurovsky VV. TRAIL-mediated enhancement of collagen production by human lung fibroblasts. Arthritis Res 4, Suppl 1:A19, 2002. 64. Yurovsky VV. Molecular cross-talk between the TRAIL and TGF pathways in human lung fibroblasts. J Invest Med 50:168A, 2002. 65. Yurovsky V. TRAIL-induced TGF -mediated collagen production by human lung fibroblasts. FASEB J 16:A1078, 2002. 66. Yurovsky VV. Molecular cross-talk between the TRAIL and TGF- pathways in human lung fibroblasts. Arthritis Res Ther 5, Suppl 1:64, 2003. 67. Yurovsky VV. TRAIL enhances collagen production by human lung fibroblasts. J Invest Med 51:S369, 2003. 68. Storozheva Z, Kostanyan I, Bogachuk A, Proshin A, Surina E, Yurovsky V. New protective peptide for neurodegeneration correction: effect on beta-amyloid toxicity. In: 6th IBRO Congress of Neuroscience, Prague, Czech Republic, 2003. 69. Yurovsky VV. Cross-talk between TRAIL and TGF- in regulation of collagen production in scleroderma lung disease. Arthritis Res Ther 6, Suppl 1:26, 2004. 70. Yurovsky VV. Cross-talk between the TRAIL and TGF pathways in regulation of collagen production by lung fibroblasts. Clin Invest Med 27:209C, 2004. 71. Yurovsky VV. Effects of tumor necrosis factor-related apoptosis-inducing ligand on extracelluler matrix production in lung fibroblasts. International Conference on Biomolecular Science, Moscow, Russia. Abstracts, p. 49, 2004. Proffered Communications 1. Oral presentation “Interactions of type 2 CD8+ T cells and fibroblasts in scleroderma lung disease�. 20th European Rheumatology Research Workshop, Oxford, UK. March 2000.