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Curriculum Vitae D. Kojo Hamilton, M.D. Assistant Professor, Department of Neurosurgery University of Maryland School of Medicine

December 21, 2010 University of Maryland Dept. of Neurosurgery 22 South Greene St , S-12-D Baltimore, Maryland 21201-1595 TEL: (410) 328-6148 FAX: (410) 328-0756 khamilton@smail.umaryland.edu

Education 1995-1998

1998 2003

University of Maryland, College Park Major: Biochemistry, Undergraduate Research in Cell and Molecular Biology Bachelor of Science with High Honors University of Virginia School of Medicine, M.D.

Post Graduate Education and Training 2003 - 2007 Neurological Surgery Resident: University of Virginia Health System 2007 - 2008 Brain and Spine Fellowship, Auckland City Hospital, Auckland New Zealand 2008 - 2009 Chief Resident, Neurosurgery, University of Virginia Health System. 2009 - 2010 Complex Spine Fellowship, UVA Neurosurgery/Orthopedic Surgery Mentors: Drs. Chris Shaffrey and Vincent Arlet

Certifications ABNS Primary Examination: May 2007 USMLE, Step 3, December 15, 16, 2003 ACLS, May 8, 2003 USMLE, Step 2, July 15, 2002 USMLE, Step 1, June 15, 2001 AHA-BLS, September 1999, 2010

Licenses Maryland (Active)

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Employment History Academic Appointments 2010-present Assistant Professor (tenure track) of Neurosurgery University of Maryland School of Medicine Research Experience 2006-2007 Investigated the effects of trans-sodium crocetinate (TSC), a pharmaceutical agent; as a modulator of radiation therapy and radiosurgery, using C6 glioma cells in a rat model. Lab director: Dr. Jason P. Sheehan (Asst. Professor of Neurological surgery, Department of Neurosurgery, University of Virginia Health System). 2002-2004

Completed analysis and review, of medical therapy and neurological surgery intervention of refractory and recurrent pituitary prolactinomas. Mentor: Edward Laws Jr. M.D. (Professor of Neurological surgery, Department of Neurosurgery, University of Virginia Health System 19922007)

1997-1999

Performed independent undergraduate thesis research into plant transcription factors activated in response to chemical stress. Mentor: Jonathan Arias Ph.D. (Molecular and Cell Biology Program, University of Maryland College Park, Assistant Professor).

Research in Progress Effects on cardiac output and end organ function by Vasoactive Pressors (Epinephrine and Phenylephrine) during complex spine surgery. Hamilton DK, Thiele R, Lynch C, Nermegut E, Shaffrey C. Change in Sexual Function following Major Scoliosis Surgical Intervention. Hamilton DK, Gillespie E.H., Shaffrey CI. Rare presentations of Spinal Dural Ateriovenous Fistula: Dual Extra and Intra-dural venous drainage. Hamilton DK, Jensen ME, Dumont AS. (Accepted, spine joint section AANS/CNS 2010) Other Employment 1/4/-7/5/1999 Genelogic Incorporated (Gaithersburg, Maryland) Research Associate, III: Supervised the daily planning and execution of sequencing DNA extracts for Pharmaceutical Gene database. Personally responsible for sequence matching and quality control and progress report presentations.

Professional Society Memberships 1988-1994 Ghana Red Cross Society (Cape Coast Chapter)

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1995-1998 1996-1997 1999-2003 2000-2001 2000-2001 2003 2003 2007

Charles R. Drew Premedical Society, CRDPS, (University of Maryland) Chapter Treasurer (CRDPS) American Medical Student Association (AMSA) Geriatric Medicine National Coordinator (AMSA) Student National Medical Association (UVA Chapter Treasurer) American Association of Neurological Surgeons (AANS) Congress of Neurological Surgeons (CNS) AOSpine North America (AOSNA)

Honors and Awards 1993 1994 1996 1997 1997 1998 1998 1998-1996 1999 2000 2002 2002 2009 2009

F.L. Bartels award for Excellence in Leadership (Mfantsipim School) Deputy Head Prefect for Academic Affairs (Mfantsipim School) Tutor of the Year in Chemistry and Physics (Univ. of Maryland, CP) Medical Academic Advancement Program (MAAP), University of Virginia Undergraduate Honors Research in Cell and Molecular Biology Howard Hughes Medical Institute Summer Research Scholarship Undergraduate Honors Research in Biochemistry Dean’s List, University of Maryland, College Park. MD Summer Clinical Fellowship in Surgery and Tropical Medicine, level 1 (Ghana Red Cross Society) Summer Clinical Fellowship in Surgery and Tropical Medicine, level 2 (Ghana Red Cross Society) Dean’s Geographic Medicine Scholarship Recipient Chief Resident Advisor, Medical Academic Advancement Program (MAAP), Univ. of Virginia Thomas G. Lowe Memorial Scholarship (Spine) AOSpine North America (AOSNA) Spine Fellowship

Publications Peer-reviewed Journal Articles 1. Pascuzzi P. Hamilton D.K, Bodily K. Arias J. Auxin-induced stress potentiates transactivation by a conserved plant basic/leucine-zipper factor. Journal of Biological Chemistry. 273(41):26631-7, 1998 Oct 9. 2.

Hamilton DK, Vance ML, Boulos PT, Laws ER. Surgical outcomes in yporesponsive prolactinomas: analysis of patients with resistance or intolerance to dopamine agonists. Pituitary. 2005;8 (1):53-60.

3.

Hamilton DK, Bourne TD, Ahmed H, Cousar JB, Mandell JW, Sheehan JP.Follicular lymphoma of the dura: case report. Neurosurgery. 2006 Sep;59 (3):E703-4; discussion E703-4.

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4.

D. Kojo Hamilton, Neal F. Kassell, Mary E. Jensen and Aaron S. Dumont. Subarachnoid hemorrhage and diffuse vasculopathy. Case report: Journal of Neurosurgery March 2007 Volume 106 Number 3.

5.

Hamilton DK, Jones-Quaidoo SM, Sansur C, Shaffrey CI, Oskouian R, Jane JA Sr. Outcomes of bone morphogenetic protein-2 in mature adults: posterolateral noninstrument-assisted lumbar decompression and fusion. Surg Neurol. 2008 Jan 17; [Epub ahead of print]

6.

Sheehan J, Ionescu A, Pouratian N, Hamilton DK, Schlesinger D, Oskouian RJ Jr, Sansur C.Use of trans sodium crocetinate for sensitizing glioblastoma multiforme to radiation: laboratory investigation. J Neurosurg. 2008 May;108(5):972-8.

7.

Medel R, Crowley RW, Hamilton DK, Dumont AS. Endovascular obliteration of an intracranial pseudoaneurysm: the utility of Onyx. J Neurosurg Pediatr. 2009 Nov;4(5):445-8.

8.

Joaquim AF; D. Kojo Hamilton; Sansur CA, Shaffrey CI. Degenerative Lumbar stenosis: Arq Neuro-Psiquiatr. 2009;67(2-B): 553-558.

9.

Sansur, CA, Reames, DL, Smith, JS, Hamilton DK, Berven, SH, Broadstone, PA, Choma, TJ, Goytan, MJ, Noordeen, HH, Knapp, DR, Hart, RA, Zeller, RD, Donaldson, WF, Polly, DW, Perra, JH, Boachie-Adjei, O, and Shaffrey, CI. Morbidity and mortality in the surgical treatment of 10,242 adults with spondylolisthesis: J. Neurosurg Spine. 2010 Nov; 13(5):589-93.

Book Chapters 1. Book Chapters in: Laws ER, Lanzino G (eds): Transsphenoidal Surgery. Saunders, Philadelphia, 2010, a. Prolactinoma Surgery Hamilton DK, pp 237-242 b. Surgery for Non- functioning adenomas Hamilton DK, Jane Jr., JA pp 243248. 2.

Book Chapter in Cervical Spine Surgery: Current Trends and Challenges, edited by Drs. Mummaneni, Kanter, Wang, and Haid, Discover Technique and Outcomes Sansur CA, Hamilton DK, Shaffrey ME.

3.

Book Chapter in Youmans Neurological Surgery, sixth edition, editor: R. Winn, Flatback and Sagittal Plane Deformity. Hamilton DK, OsKouian R., Shaffrey C.I. Presentations and Abstracts

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Upper Cervical and Craniovertebral decompression: 9/04/2002 Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio Contemporary Advances in Transsphenoidal Surgery. Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio

9/18/02

Department

of

Surgical Outcomes in Hyporesponsive Prolactinomas: Analysis of Patients with Resistance or Intolerance to Dopamine Agonists: 2004 American Association of Neurological Surgeons (AANS) Annual Meeting: Orlando, Florida May 1 – May 6, 2004 Surgical Outcomes in Hyporesponsive Prolactinomas: Analysis of Male Patients with Resistance: to Dopamine Agonists. 55th Annual Meeting of the Congress of Neurological Surgeons Boston, Massachusetts 10/08/2005- 10/13/2005 Abstract/Poster Spontaneous Intracranial Hypotension (SIH): Analysis and Outcomes of Early (EpiduralBlood Patch)versus Late (Conservative Management) Treatment Options. Neurosurgical Society of the Virginias meeting January 2006 (Greenbriar) White sulphur Springs, West Virginia. Spontaneous Intracranial Hypotension: Current Analysis and Outcomes of Early versus Late Treatment Options: 2006 American Association of Neurological Surgeons annual meeting: San Fransisco, California April 24 2006. Abstract/Poster. Lumbar Decompression with non-Instrumented Posterior Lateral Fusion: Analysis of Fusion, Patient Outcomes and Complications in Adults: Neurosurgical Society of the Virginias meeting. The Homestead, Hot Springs, Virginia. January 2007 Outcome Analysis in Surgery for Adult Chiari 1 Malformation with Syringomyelia, with or without Arachnoid opening and Dural Graft: American Association of Neurological Surgeons annual meeting: Chicago, Illinois, April 29, 2008. Plenary Session II Morbidity and Mortality in the Surgical Treatment of 10,329 Adults with Degenerative Lumbar Stenosis: A Report from the Scoliosis Research Society (SRS) Morbidity and Mortality Committee: Fu KG, Smith JS, Sansur C, Hamilton DK, Donaldson WF III, Perra JH, Mudiyam R, Choma TJ, Zeller RD, Knapp RD, Noordeen HH, Berven SH, Goytan MJ, Boachie-Adjei O, Shaffrey CI: AANS/CNS section on Disorders of the Spine and Peripheral Nerves: March 11-14, 2009 Phoenix, AZ Short-term Morbidity and Mortality Associated with Correction of Thoracolumbar Fixed Sagittal Plane Deformity: Sansur CA, Smith JS, Hamilton DK, Fu KM, Jagannathan J, Donaldson WF III, Perra JH, Mudiyam R, Choma TJ, Zeller RD, Knapp RD, Noordeen HH, Berven SH, Goytan MJ, Boachie-Adjei O, Shaffrey CI: AANS/CNS section on Disorders of the Spine and Peripheral Nerves: March 11-14, 2009 Phoenix, AZ Complications in the Surgical Treatment of 2,258 Adults with Isthmic Spondylolisthesis: A Report from the Scoliosis Research Society Morbidity and

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Mortality Committee: Smith JS , Sansur CA, Hamilton DK, Fu KM, Donaldson WF III, Perra JH, Mudiyam R, Choma TJ, Zeller RD, Knapp RD, Noordeen HH, Berven SH, Goytan MJ, Boachie-Adjei O, Shaffrey CI: AANS/CNS section on Disorders of the Spine and Peripheral Nerves: March 11-14, 2009 Phoenix, AZ Complications associated with BMP use 11,281 cases of spinal fusion: A Report from the Scoliosis Research Society Morbidity and Mortality Committee. Williams BJ, Fu KM, Smith JS, Hamilton DK, Perra JH, Shaffrey CI. Complication Rates for the Surgical Treatment of 6,624 Patients with Degenerative Spondylolisthesis: Lumbar Spine Research Society: Chicago, IL. April 2-3 2009 Risk-Benefit Assessment of Surgery for Adult Scoliosis: An Analysis Based on Patient Age: Lumbar Spine Research Society: Chicago, IL. April 2-3 2009 Prevalence and Severity of Foramenal and Central Canal Stenosis Among Adults with Degenerative Sclerosis: Lumbar Spine Research Society: Chicago, IL. April 2-3 2009 Outcome of Bone Morphogenetic Protein-2 in the Elderly: Posterior Cervical Fusion:2009 American Association of Neurological Surgeons annual meeting:San Diego, California, May 2-6 C2 Neurectomy During Atlanto-Axial Instrumented Fusion in the Elderly: Patient Satisfaction and Surgical Outcome: 2009 American Association of Neurological Surgeons annual meeting: San Diego, California, May 2-6 Rates of Neurological Injury Associated with Spine Surgery Based on 108,419 Procedures: A Report of the Scoliosis Research Society Morbidity and Mortality Committee: Congress of Neurological Surgeons annual meeting: New Orleans, Louisiana, October 26 2009 Rare Presentation of Spinal Dural Arteriovenous Fistula: Dual Extra and Intradural Venous Drainage: AANS/CNS section of Disorders of the Spine and Peripheral Nerves: February 17-20, Orlando, FL Changes in Sexual Function in Older Adults Following Thoracolumbar to Pelvic Instrumentation for Spinal Deformity: Congress of Neurological Surgeons Annual Meeting: San Francisco, California, October 18, 2010 Comparison of the Incidence of Complications of Posterior Cervical Fusion with and without BMP: A Report of the Scoliosis Research Society Morbidity and Mortality Committee Williams, BJ, Smith, JS, Fu, KMG, Hamilton, DK, Polly, D, Jr., Ames CP, Berven, SH, Perra, JH, Knapp, DR Jr., McCarthy, RE, Shaffrey, CI (Cervical Spine Research Society 38th Annual Meeting, December 2-4, 2010, Charlotte, NC) Poster Presentation Comparison of the Incidence of Complications of Anterior Cervical Fusion with and without BMP: A Report of the Scoliosis Research Society Morbidity and Mortality 6


Hamilton, DK, Polly, D, Jr., Ames CP, Berven, SH, Perra, JH, Knapp, DR Jr., McCarthy, RE, Shaffrey, CI (Cervical Spine Research Society 38th Annual Meeting, December 2-4, 2010, Charlotte, NC) Platform Presentation

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