MinJung Kim Post-Doctoral Fellow mjkim @som.umaryland.edu
Education:
BS in Genetic Engineering from Cheongju University, Korea MS in Genetic Engineering from Cheongju University, Korea MS in Molecular and Cell Biology from University of Texas at Dallas Ph.D. in Molecular and Cell Biology from University of Texas at Dallas
Research Interests
My research project focuses on the role of microRNAs (miRs) that regulate normal erythroid development in human hematopoietic stem-progenitor cells (HSPCs). This project involves in the identification of lineage- and stage-specific miRs that regulate the expression of key mRNAs. In addition, we are also interested in understanding how hypoxia inducible factor-1Îą (HIF-1Îą) and hypoxia-related miRs are involved in the regulation of early HSPC proliferation, survival, and differentiation.
Laboratory Experiences
Cloning of a gene from new tRNA splicing mutant of Schizosaccharomyces pombe. Cheongju University, Cheongju, Korea (1999-2000) Transcription of Schizosaccharomyces pombe thioltransferase-1 in response to stress conditions. Cheongju University, Cheongju, Korea (2001-2003) Regulatory factor interactions and somatic silencing of the germ cell-specific ALF gene. University of Texas at Dallas, Dallas, TX (2003-2006) Developmental and cell type-specific regulation of core promoter transcription factors in germ cells of frogs and mice. University of Texas at Dallas, Dallas, TX (2004-2006) Organization and transcriptional output of a novel mRNA-like piRNA gene (mpiR) located on mouse chromosome 10. University of Texas at Dallas, Dallas, TX (2006-2007) MicroRNAs regulating erythroid development. University of Maryland School of Medicine, Baltimore, MD (2008-Present) Interplay of hypoxia-inducible factor-1 (HIF-1) and microRNAs in regulation of human erythropoiesis. University of Maryland School of Medicine, Baltimore, MD (2008Present)
Publications
MinJung Kim, Bhavita Patel, Kourtney E. Schroeder, Abbas Raza, and Jeff DeJong (2008) Organization and transcriptional output of a novel mRNA-like piRNA gene (mpiR) located on mouse chromosome 10. RNA 14(6), 1005-1011. MinJung Kim, Dan Li, Yunxia Cui, Konrad Mueller, William C. Chears, and Jeff DeJong (2006) Regulatory factor interactions and somatic silencing of the germ cellspecific ALF gene. J. Biol. Chem. 281(45), 34288-34298. LiJuan Xiao, MinJung Kim and Jeff DeJong (2006) Developmental and cell typespecific regulation of core promoter transcription factors in germ cells of frogs and mice. Gene Expr. Patterns, 6(4), 409-419. Minjung Kim, Kuchan Hwang, Chang-Jin Lim, and Daemyung Kim (2002) A potential membrane protein involved in pre-tRNA splicing of Schizosaccharomyces pombe., Biochim. Biophys. Acta, 1574(2), 210-214. Minjung Kim, Chang-Jin Lim, and Daemyung Kim (2002) Transcription of Schizosaccharomyces pombe thioltransferase-1 in response to stress conditions. J. Biochem. Mol. Biol., 35(4), 409-413