Scientific Highlights
Issue 3/20
J Oral Implantol. 2020 Apr 16. doi: 10.1563/aaid-joi-D-19-00119. [Epub ahead of print]
Maxillary sinus floor elevation surgery with biooss mixed with enamel matrix derivative: a human randomized controlled clinical and histological study. Vincent-Bugnas S, Charbit Y, Charbit M, Dard M, Pippenger B.
Abstract Xenograft bone substitutes are commonly used to increase bone volume and height in the deficient posterior maxilla. The
addition of enamel matrix derivate (EmdogainÂŽ) could increase the efficiency of the bone healing process. The aim of this
prospective randomized, controlled split-mouth design study was to compare the percentage of newly formed bone in sinus
floor augmentation with deproteinized bovine bone mineral with or without the addition of enamel matrix derivative after 6 months of healing.
Sixteen bilateral sinus floor augmentation procedures were performed. Deproteinized bovine bone mineral combined with
enamel matrix derivative (test) and deproteinized bovine bone mineral alone (control) groups were randomly allocated within each patient.
Six months after augmentation and concurrent to implant placement, bone biopsies were taken for histomorphometric
analysis. Additionally, implant survival and peri-implant bone levels were radiographically assessed at baseline and 24 months after functional loading.
Results •
Histomorphometric analysis revealed a significantly higher amount of newly formed bone in the test group compared to the control group (22.6% and 15.5%, p=0.033 respectively).
•
No significant differences in the amount of remaining graft or connective tissue was found.
Conclusions Enamel matrix derivative added to deproteinized bovine bone mineral particles significantly increased new bone formation in
sinus lift procedures in edentulous or partially edentulous patients with deficient bilateral posterior alveolar ridges requiring augmentation for implant placement.
Adapted from Vincent-Bugnas S et al., J Oral Implantol. 2020 Apr 16, for more info about this publication click HERE
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