BIOAVAILABILITY (adjective)
Physiology (of a drug or other substance) entering the circulation when introduced into the body and so able to have an active effect. ‘bioavailable oral antibiotics’ ‘highly bioavailable forms of nutrients’
CBD & BIOVAILABILITY
CBD can be delivered to the bloodstream sublingually (under the tongue), orally, inhaled, or topically on the skin through a range of delivery methods including oils, tinctures, sprays, creams, capsules, vaporizers and food products. These delivery methods vary greatly in terms of absorption which can have a significant impact on bioavailability. A number of factors can affect absorption, including the drug’s properties, the way the product is designed and even the way the drug is stored. Too low bioavailability can hamper the ability of a drug to provide effective treatment. Within the oral mucosal cavity, the buccal and sublingual regions offer an attractive route for drug administration, because the bioavailability ranges from 15 to 25%.
Buccal Delivery System
Buccal
Sublingual
Fast absorption and high bioavailability. The buccal mucosa offers a near ideal non-invasive portal through which natural products can enter directly into the blood stream. Among the challenges of formulating phytocannabinoids as supplements or medicines are their lipophilicity and slow absorption.
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