Issue No. 33 • MICA (P) 108/03/2015
A NCCS QUARTERLY PUBLICATION April – June 2015
...HELPING R E A DER S TO ACHIEV E GOOD HE A LT H
Salubris is a Latin word which means healthy, in good condition (body) and wholesome.
CANCER IMMUNOTHERAPY – A RISING ADDITION FOR CANCER TREATMENT
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SALUBRIS APRIL – JUNE 2015
CANCER IMMUNOTHERAPY – A RISING ADDITION FOR CANCER TREATMENT BY DR TOH HAN CHONG Division of Medical Oncology
Cancer Immunotherapy was voted by prestigious Science journal as the Breakthrough of the Year for 2013. The rise of the field to place of prominence has come a long way since the early research work in the 18th century by Dr Edward Jenner, the ‘Father of Vaccines’.
I
mmunotherapy consists of four main groups of treatment including cellbased therapy, monoclonal antibody therapy, cytokine therapy and therapeutic cancer vaccine. These treatments exploit the fact that cancer cells often have subtly different proteins on their surface that can be targeted by the immune system. Developments in cancer immunotherapy towards real benefit for patients only emerged in recent years where the application of anti-cancer monoclonal antibodies for cancer patients and the approval of the first therapeutic cancer vaccine by the FDA for the treatment of advanced prostate cancer in 2010. More recently, antibodies that release the brakes on the body’s immune cells to strike directly at the cancer have shown some very impressive results in several cancers. Harnessing the body’s T cells and re-engineering these T cells to fight relapsed leukaemia have also shown some very dramatic results, including rendering some patients cancer-free.
HOW THE VACCINE WORKS Visualising the construct as individual entities, MUC-1 represents the ‘target’ while CD40L is the ‘stimulator’. The ‘stimulator’ will facilitate enhancement of the body’s immune system, driving the T-cells to better seek out the ‘target’ (MUC-1) found only on the surface of the cancer.
In 2014, National Cancer Centre Singapore conducted a first-in-human clinical phase I trial using a novel cancer vaccine developed by US biotech company, MicroVAX. This first-in-human trial employs a unique vaccine that features a common cancer protein MUC-1, attached to a booster protein CD40-ligand (CD40L), to form a construct call MUC-1+CD40L. The construct is then fitted into the backbone of the common cold virus called adenovirus, which further enables the vaccine to more effectively boost the body’s immune system, targeting the MUC-1 protein expressed in cancers such as ovarian, breast, prostate, colorectal and lung cancer.
As the cancer vaccine is built into an adenovirus, even though the virus has been disabled, approval seeking was a challenge at first with multiple regulatory hurdles to clear. The clinical trial eventually received endorsements from both US Food and Drug Administration (FDA) and then the Health Sciences Authority (HSA) to proceed.
CYTOTOXIC T LYMPHOCYTE
TUMOUR
SALUBRIS APRIL – JUNE 2015
Six patients have received the cancer vaccine and have no significant side effects to date. One patient with advanced breast cancer with cancer spread to her skin and soft tissue under the skin developed a skin rash about two weeks after treatment which disappeared a few days later. Her cancer marker has decreased significantly which is an encouraging sign, and she will be assessed as per trial schedule with CT scans. This is the first clinical trial to be sponsored by Singapore Clinical Research Institute (SCRI), which has created a vital partnership structure to attract novel cancer therapies to Singapore in collaboration with especially smaller global biotech companies.
For enquiries to participate in the trial, the public can contact NCCS clinical research coordinator Ms Chong Hui Shan at +65 6436-8431 or chong.hui.shan@nccs.com.sg. General information about clinical trials is also available online at www.nccs.com.sg.
PATIENT PROFILE
MRS JANET QUAH ( 王花蓉 ) AGE 60 Mrs Janet Quah was diagnosed with Stage IV breast cancer in 2009. She was subsequently referred to Dr Toh Han Chong and has since been under his care. Janet had undergone various treatment including surgery, chemotherapy, radiotherapy and anti-cancer hormone therapy with the cancer spreading to lungs and lymph nodes.
Janet was recruited as she has elevated tumour marker CA15-3 which is a criteria for enrolment into this study. Even before consulting her family members, she was determined to participate in the trial.
MHC I-peptide complex
DC
Antigen-specific T lymphocyte activation in Lymph nodes
DC activation and antigen presentation
DC Fusion protein uptake by DC
MUC-1
CD40L
Fusion protein expression & excretion (e.g. fibroblasts)
Infect
DNA
CD40L
Ad-hMUC-1/ ecdCD40L vaccine
MUC-1
Subcutaneous injection of vaccine
Adapted from Dr Nancy Helm, Columbia University.
She was seen by Dr Toh for six years and said that she had a lot of confidence in him. She believes that participating in the trial might potentially benefit her as well as future patients. She started on the cancer vaccine in December 2014 and has yet to experience any side effects. Janet is currently working as an administration manager. She has 3 children and in her free time, she enjoys reading, leisure walking at East Coast Park with her daughter and sister-in-law, and also indulges in sourcing for gourmet delicacies and shopping.
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SALUBRIS APRIL – JUNE 2015
CERVICAL CANCER BY DR DAVID TAN AND DR IRIS SIN
Uterus
Division of Radiation Oncology
The cervix is located at the lower end of the womb where it opens into the vagina. Cervical cancer occurs when the cells of the cervix grow in an uncontrolled manner.
C
ervical cancer was the 2nd most common gynaecologic cancer in women in 2012 1, and it is the 4th most common cancer in women in Singapore 2. The incidence in countries is dependent on the availability of screening programmes and human papillomavirus vaccine.
Cervix Vagina
Cervix viewed from below
FIGURE 1: CERVICAL CANCER Courtesy of http://imgkid.com/cervical-cancer-stages.shtml
RISK FACTORS
SCREENING
The human papillomavirus (HPV) has been found to be a major implication in the development of cervical cancer and can be detected in 99.7% of cases. HPV is the most common infection of the reproductive tract and most sexually active women and men will be infected at some point in their lives. However, persistent infection with certain types of HPV may eventually lead to cervical cancer, and the time taken for this to happen (up to 20 years) may be shortened in individuals with a weakened immune system.
Because patients with early stages of cervical cancer are usually symptom-free, screening plays an important role in early detection and treatment. The main method for screening involves evaluation with the Papanicolaou (Pap) test that looks at the cells from the cervix under the microscope.
Risk factors include: • Early age of sexual activity or multiple sexual partners • A high risk sexual partner
In Singapore, screening is recommended for women aged 25 years old and above, who have ever had sex or are sexually active, and is routinely done once every 3 years. Women who have never had sexual intercourse need not have a Pap smear. However, if these women develop symptoms, they should seek medical advice.
• A history of sexually transmitted diseases e.g. chlamydia • Compromised immune system • Smoking • Oral contraceptive use • Non-adherence to screening
PRESENTATION Patients with early stages of cervical cancer usually do not have any symptoms, and these cases are usually picked up as part of screening. However, if symptoms do occur, the most common presentations include bleeding during or after sexual intercourse, bleeding in between menstruation, post-menopausal bleeding or foul smelling discharge. In the later stages, patients may have complaints relating to local or distant spread, such as blood in the urine, blood in the stools or back pain.
The process of getting a Pap smear done involves a speculum being inserted into the vagina to look at the cervix. A small brush will be used to obtain some cells from the cervix to be sent for analysis. After the smear is done, the doctor or nurse may perform an internal examination that involves inserting two fingers into the vagina to assess the cervix and also putting another hand on the lower abdomen to assess the uterus and ovaries. Some women may experience some discomfort during the procedure, but it should not cause any pain.
SALUBRIS APRIL – JUNE 2015
RESULTS
PREVENTION 3
The results of the Pap smear should be made available about 2-3 weeks after it has been done. Depending on the results of the Pap smear, your doctor may advise the following:
HPV vaccination can help to reduce the chances of cervical cancer. It works by preventing infections by the strains of HPV that are most associated with cervical cancer. There are two types of vaccines available in Singapore – Cervarix and Gardasil.
• Non-cancerous cells: routine screening • Cervical intra-epithelial neoplasia (pre-cancerous lesions): colposcopy – involves using a colposcope, which is an instrument containing a magnifying glass, to visualise the cervix and to inspect it more carefully. To do so would require the use of a speculum, which is the same device used to open up the vagina for the Pap smear. • Cancerous lesions: referral to a gynaecologist for further management 3
Gardasil
Cervarix
Protection against
HPV 6, 11, 16, 18
HPV 16, 18
Prevents
Cervical cancer, vulvar cancer, vaginal cancer, genital warts *
Cervical cancer
* HPV 6 and 11 also known to cause about 90% of genital warts
The vaccination schedule depends on the vaccine that has been chosen. It is approved for females between 9 and 26 years old. It is most effective if administered before first sexual intercourse or in women who have not been exposed to the strains covered by the vaccine. Women who are already sexually active and who have not been vaccinated may still benefit from the vaccine. It is best to talk to your doctor who will be able to advise you if the vaccine is suitable for you. Note that HPV vaccination is not a substitute for cervical cancer screening – women who have received the vaccine should still continue going for their routine Pap smears. As of 1 November 2010, patients can use up to $400 per Medisave account per year to pay for HPV vaccination. Patients may also use their own Medisave or that of their immediate family members to help pay for the vaccination.
CONCLUSION Cervical cancer is a common cancer in Singapore,but with regular screening, early detection and treatment is possible. HPV vaccination helps to prevent infection with high-risk strains of HPV, hence reducing the chances of cervical cancer.
FIGURE 2: PAP SMEAR Courtesy of https://my.pearlpoint.org/resources/cervical-cancer-treatment-general-information-aboutcervical-cancer
1
World Health Organisation, Human Papilloma Virus and Cervical Cancer, http://www.who.int/mediacentre/ factsheets/fs380/en/
2
Cervical Screen Singapore, Management Guidelines for Abnormal Pap Smear and Preinvasive Disease of the Cervix, Health Promotion Board Singapore
3
Health Promotion Board, FAQs on Human Papilloma Virus (HPV) and HPV Vaccination, http://www.hpb.gov.sg/ HOPPortal/health-article/8768
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SALUBRIS APRIL – JUNE 2015
BRINGING FESTIVE CHEER TO CANCER PATIENTS BY LIN SHUANGCHUN Community Partnership
It was a day with a difference for visitors to the National Cancer Centre Singapore. A group of volunteers went around distributing mandarin oranges on 17 February.
T
his gesture was done in the spirit of the Chinese New Year, with the sponsorship of M/s Event Security Specialists Pte Ltd. More than $400 worth of mandarin oranges and carrier bags as well as other festive goodies were distributed to the patients.
Two volunteers Yao Bin and Si Ying, took time off from their busy work schedule to join the staff of NCCS’ Community Partnership department to distribute the goodie bags.
Together with mascot, Buddie the Badger, the giveaway certainly brought the joy and smiles to many faces. A total of 250 festive goodie bags were given out Buddie standing in as the ‘God of Fortune’ shaking hands and wishing good luck to patients and visitors.
SALUBRIS APRIL – JUNE 2015
REVERING THE UNSUNG PROTAGONISTS IN HEALTHCARE BY HUANG QIANWEI Anglo-Chinese Junior College
This year’s Chinese New Year is different. We students from ACJC no longer hold our own celebrations within the confines of our college. Instead, we are having a more meaningful celebration by going around Singapore to thank all those who have served and contributed to the 50 years of our nation’s success. National Cancer Centre Singapore is one of those we are thankful for. They work tirelessly to battle cancer and care for the ill, inspiring us with their passion for a good cause.
The team of students with alumni, Dr Toh Han Chong
Thanking nurses behind the scenes
A
s we stepped into NCCS, donned in our red ACJC collegiate, we were welcomed by the endearing badger that is the mascot of the centre, as well as the hospitable staff who introduced us to their unique work culture with pride and confidence. With the help of some staff members, we walked around and gave out oranges and thank you cards to the staff. We visited clinics and even labs, gaining more insight into their work along the way. We saw how the staff encourage one another to pull through despite the challenges; we saw how they exude warmth and give a helping hand to their patients. Besides thanking the lab researchers, doctors and nurses, we also thanked the cleaning aunties and uncles who are also dedicated in keeping this place clean and pristine. We found it gratifying to see the smile on their face as we give out oranges and well wishes, as much as the staff here found their job gratifying when they help patients recover.
Spreading the love at NCCS
Before we left, we received goodie bags from the centre to thank us in return. Inside was the badger we saw when we first arrived. They explained that the badger is a symbol of tenacity and resilience, that is, the spirit to cheer on and persevere in fighting cancer and promoting greater awareness. I realised just how fortunate we are to live in the age of technological advancements that are not devoid of human warmth. We thank the NCCS for their generosity and hospitality, as well as their service and contribution to the society. Appreciations for keeping the premise pristine with pride
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SALUBRIS APRIL – JUNE 2015
CONGRATULATIONS TO THE WINNERS! STAFF RECOGNITION AWARDS 2015 Special Awards
Ms Chua Gek Phin
Dr Gilbert Fan
Director, Nursing Administration
Master Medical Social Worker, Psychosocial Oncology
National Day Awards EFFICIENCY MEDAL Ms How Gek Nai Gina Nurse Manager, SOC ‘C’ Clinic
NCCS CARE Excellence Awards Mr Andy Lin Yufeng Radiographer, Oncologic Imaging
Ms Ng Lai Kuan Senior Staff Nurse, Oncologic Imaging
LONG SERVICE MEDAL
Ms Venicia Chong Hwee Ghee
Dr Fong Kam Weng
Patient Relations Officer, Radiation Oncology
Head, Radiation Oncology
Ms Chew Yung Hwui
Ms Chua Gek Phin
Staff Nurse, Nursing (ATU)
Director, Nursing Administration
Ms Leong Kum Foong
Ms Chan Geok Luan Irene
Cashier, Finance
Principal Radiation Therapist, Radiation Oncology
Mr Billy Tan Pee Lee
Ms Yoong Yim Kuen
Senior Executive, Business Development
Principal Radiation Therapist, Radiation Oncology
Ms Parvathy d/o Peria Karuppan
Ms Sukarmi Bte Katani
Patient Service Officer, Clinic Operations
Senior Executive, Radiation Oncology
NATIONAL MEDICAL RESEARCH COUNCIL AWARDS 2015 Singapore Translational Research (STaR) Investigator Award
NMRC Research Training Fellowship
Professor Teh Bin Tean
R&D Dosimetrist, Division of Radiation Oncology
Principal Investigator, Division of Medical Sciences
Ms Hu Jing Mr Eric Pang Pei Ping Senior Radiation Therapist, Division of Radiation Oncology
Clinician Scientist Award Senior Investigator Category
Dr Iain Tan Bee Huat Consultant, Division of Medical Oncology
Transition Award Dr Melvin Chua Associate Consultant, Division of Radiation Oncology
MOH Health Research Scholarship (MCI) Dr Chia Seng Hup Registrar, Division of Radiation Oncology
Dr Chua Wei Ling Clarinda Associate Consultant, Division of Medical Oncology
SALUBRIS APRIL – JUNE 2015
TRIBUTES TO PIONEER GENERATION COLLEAGUES
Our achievements would not have been possible without the unwavering dedication and commitment of our pioneers’ tireless contributions and sacrifices.
As Singapore turns 50 this year, we would like to take this opportunity to salute and hail our Heroes, our pioneers, in the setting of the visionary medical healthcare that you see today.
Thank you for sowing the seeds of the successes we have today, for building NCCS as an internationally and worldwide acclaimed global cancer centre.
FROM LEFT TO RIGHT:
ABSENT:
1.
Ms Chew Pheck Geok
7.
Mr Mumtaz Ahmad Bin M. S.
Director, Radiotherapy Services
Technician, Photographic
Director, NCCS
2.
Dr Vijay Kumar Sethi
8.
Mr Ng Kim Bock
Ms Foong Yin Ling Eunice (PIONEER)
Senior Advisor, NCCS
Consultant Physicist
3.
Ms Ong Geok Hwa Madeleine
9.
Mr Ong Choo Bee
Manager, Radiation Oncology
Clerk, Medical Records
4.
Ms R. Bagavathi Ammal w/o G. R.
Health Care Attendant
5.
Dr Chua Eu Jin
Senior Consultant, Radiation Oncology
(PIONEER)
(PIONEER) (Retired) (PIONEER)
(Retired)
(PIONEER)
6.
Ms Goh Kah Gek
Patient Service Coordinator
(PIONEER)
(PIONEER)
(PIONEER)
10.
Mr Wong Toh Jui
Consultant Physicist
11.
Dr Wee Tien Seng Joseph
Chairman, Medical Board
(PIONEER)
(PIONEER)
Prof Soo Khee Chee (PIONEER)
Administrative Assistant
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SALUBRIS APRIL – JUNE 2015
WORLD CANCER DAY AWARENESS ROADSHOW 2015 BY ALICIA PANG Cancer Education & Information Service
With the rising incidence of cancer in Singapore, World Cancer Day (which is observed on 4 February) presented another opportunity to empower the public with cancer knowledge to raise cancer awareness. This is a time to encourage the community to adopt healthier lifestyles as well as go for early screening.
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he National Cancer Centre Singapore (NCCS) held a roadshow at Woodlands Civic Centre on 7 February as part of its outreach to the community. Three screening information counters were set up to address the top three cancers in Singapore, namely Colorectal, Breast and Lung cancers. Faecal Immunochemical Test (FIT) kits collection was made available to those who are 50 years old and above, while women were were taught breast self-examination.
Good public interest to seek information on cancer
Another counter offered the public a chance to check the carbon monoxide level in their breath with the aid of the smokerlyzers. A quiz added the buzz for the visitors whose brains were picked as they sought the answers to the questions on cancer which were contained in the posters and the lung model. Through the questions, important messages on early detection and prevention were put across.
Educational and interactive activities were most popular among the children and youth. Many children were excited and eager to conquer the activities by themselves. This explained the common heartwarming scene of parents trying to hint the correct answers to their children.
At the end of the day, the participants not only learnt about cancer but also received tokens for the activities and Buddie the Badger plush toy. Buddie will serve as a fond reminder of their time spent at the roadshow and more importantly, their own effort in the fight against cancer.
SALUBRIS APRIL – JUNE 2015
The information on cancer attracted the young and the elderly
Through the collaboration and the encouraging public response we can move forward in creating a cancer-free tomorrow – Cancer. It is not beyond us.
The games are fun and the children enjoyed the interactive exhibits
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SALUBRIS APRIL – JUNE 2015
世界癌症日2015路展 彭薇洳 癌症教育与资讯服务
二月四日是世界癌症日！ 有鉴于新加坡的癌症患病率逐 年增加，这一个特地为癌症而设的日子别具意义。这一天 不但为我们提供了一个向公众宣导癌症意识、传达健康 生活重要性的的良好机会，也让我们提醒公众在面对任 何癌症征状时应及早就医以及定期做癌症筛检的重要。
既富教育意义又不失娱乐 性的互动活动最受年轻人 和小朋友的欢迎。许多小 孩对游戏跃跃欲试，也急 于独自完成。家长们也被 孩子的反应牵动，会场上 不难见到家长们为孩子找 不到答案而不断地给予提 示的温馨情景。
路展结束后，公众不 但带回许多参加游戏 的小礼物也抱回了绒
配合世界癌症日，新加坡国立癌症中
乳癌癌筛查资讯柜台也教女士们
心在 2015 年2月7日于兀兰民事中心
如何自行检查乳房 。公众也有机
主办了一次路展，希望通过一系列适
会通过一氧化碳监测仪检测口气
合不同年龄层的活动提高民众对癌症
内一氧化碳的含量。
的认识。 路展上设有问答游戏。问答游戏的 结肠直肠癌、乳癌和肺癌是本地最
答案可在海报和模型上找到。因
常见的癌症。在路展上，结肠直肠
此，公众无需担心自己答不出来。
癌筛查资讯的柜台有分派粪便免疫
我们希望通过这些简单轻松的问答
化学试验给50岁或以上的公众。
活动来提高公众对癌症的意识。
“路展的概念很好，能够有效地向新加坡人传达照顾身体健康的重要性。” – 公众的赞言
毛玩具- Buddie 。 希望 Buddie 绒毛玩 具会让公众想起在 路展所学的癌症讯 息以及 Buddie 的抗 癌精神。
SALUBRIS APRIL – JUNE 2015
“我们在路展上得到很多资讯。” – 公众感谢主办单位的回馈
只要万众一心，我们就有机会看到 一个无癌的将来。我们宣誓：抗癌， 我们绝对做得到！
“游戏都很有趣。孩子们都玩得很开心。” – 与孩子们同时受益的父母
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SALUBRIS APRIL – JUNE 2015
ANNOUNCEMENT OF LEADERSHIP SUCCESSION
MRS TAN YEE PIN
ADJUNCT ASSOC PROF MELISSA TEO
Mrs Tan Yee Pin who was the Manager in DPO, has been appointed Head, Division of Psychosocial Oncology (DPO) from 1st January 2015.
Adjunct Assoc Prof Melissa Teo has been appointed Head, Division of Surgical Oncology from 1st February 2015.
Yee Pin is a trained clinical psychologist and medical social worker. Since joining the DPO, she started the psychological services in NCCS by establishing and providing psychological assessments and psychological interventions to help patients cope better in terms of mental well-being.
One of only three accredited surgical oncologist in Singapore, she completed her surgical residency in Singapore and in 2007, was awarded the Singhealth HMDP Award to pursue sub-specialty training in complex intra-abdominal and pelvic surgery in the University of Toronto / Princess Margaret Hospital, Toronto, Canada.
Lauded for her contributions to palliative care education, she is currently appointed as Chairperson of the Palliative Care Course for Social Workers Workgroup, Lien Centre for Palliative Care in collaboration with Singapore Association for Social Workers, and as the Lead for National Guidelines for Palliative Care Implementation Workgroup – MSW & Bereavement.
Congratulations to Yee Pin and our acknowledgements to predecessor, Dr Gilbert Fan for his invaluable contributions within the division.
Wearing multiple hats, she is also the director of the NCCS Centre for Peritoneal and Pelvic Disease, which now has the largest experience with the surgical management of peritonealbase malignancies in Asia. She is a member of the Singapore Society of Oncology, sits on the Singapore Cancer Network Sarcoma Guideline Committee, and a member of the Ministry of Health Technology Advisory Committee.
Congratulations to Adjunct Assoc Prof Melissa Teo on the new appointment.
SALUBRIS APRIL – JUNE 2015
OUTREACH – PUBLIC FORUMS
Event
Date, Time, Venue
Registration
Gynaecological Cancers
23 May 2015, Saturday
Free Admission
TOPICS: • The Female Reproductive System • Anatomy & Functions • Common Gynecological Problems • Contraceptive Pills & Hormone Replacements Therapy – Are There Health Risks? • Other Myths & Misconceptions • Cancers of the Female Reproductive System: Cervix, Ovary and Uterus • Risk Factors, Signs & Symptoms • Early Detection & Prevention • What is PAP smear? • Screening & Treatment Procedures
MANDARIN SESSION Time: 9.15am to 10.30am (Registration: 9.00am to 9.15am)
Strictly no admission for children below 12 years old.
Prostate Cancer
4 July 2015, Saturday
Free Admission
TOPICS: • What is Prostate cancer? • What are the Risk Factors, Signs & Symptoms? • What Screening Tests Should You Do to Detect Cancer Early? • What Are the Treatment Options Available?
MANDARIN SESSION Time: 9.15am to 10.30am (Registration: 9.00am to 9.15am)
Strictly no admission for children below 12 years old.
ENGLISH SESSION Time: 11.15am to 12.30pm (Registration: 11.00am to 11.15am) Peter & Mary Fu Auditorium National Cancer Centre Singapore 11 Hospital Drive Singapore 169610
ENGLISH SESSION Time: 11.15am to 12.30pm (Registration: 11.00am to 11.15am) Peter & Mary Fu Auditorium National Cancer Centre Singapore 11 Hospital Drive Singapore 169610
Registration is a MUST as seats are limited. PHONE REGISTRATION ONLY Please call: 6225 5655 Monday – Friday: 8.30am to 5.30pm
Registration is a MUST as seats are limited. PHONE REGISTRATION ONLY Please call: 6225 5655 Monday – Friday: 8.30am to 5.30pm
The information is correct at Press time. NCCS reserves the right to change programmes or speaker without prior notice.
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SALUBRIS APRIL – JUNE 2015
OUTREACH – CANCERWISE WORKSHOPS
Event
Date, Time, Venue
Registration
CancerWise Workshop – Coping Tips for Caregivers
23 May 2015, Saturday
Free Admission
Session will be conducted in English.
Strictly no admission for children below 12 years old.Registration is a MUST as seats are limited.
TOPICS: • Who is a Caregiver? • Caregiver’s Challenges Across the Cancer Trajectory • Factors Affecting Caregiver’s Stress • Taking Care by Letting Go, Letting Go by Taking Care • Tips for Caregiving • Resources for Caregivers
CancerWise Workshop – Familial and Hereditary Cancers: Why Your Family Health History is Important TOPICS: • What is Genetic Testing? • Importance of Family History in Genetic Testing • Accuracy of Gene Testing • Cancer and Genes • What Does a Mutation Look Like? • Things to Consider Before Testing • Advantages and Disadvantages
CancerWise Workshop – Oncologic Emergencies (Nurses Only) TOPICS: • Definition, Pathophysiology & Management of: · Neutropenic Sepsis · Tumor Lysis Syndrome · Hypercalcemia · Spinal Cord Compression · Increased Intracranial Pressure · Superior Vena Cava Obstruction · Anaphylaxis
1.00pm – Registration 1.30pm to 3.30pm – Workshop starts Peter & Mary Fu Auditorium National Cancer Centre Singapore 11 Hospital Drive Singapore 169610
PHONE REGISTRATION ONLY Please call: 6225 5655 Monday – Friday: 8.30am to 5.30pm
20 June 2015, Saturday
Free Admission
Session will be conducted in English.
Strictly no admission for children below 12 years old. Registration is a MUST as seats are limited.
1.00pm – Registration 1.30pm to 3.30pm – Workshop starts Peter & Mary Fu Auditorium National Cancer Centre Singapore 11 Hospital Drive Singapore 169610
PHONE REGISTRATION ONLY Please call: 6225 5655 Monday – Friday: 8.30am to 5.30pm
4 July 2015, Saturday
Free Admission
Session will be conducted in English.
Strictly no admission for children below 12 years old. Registration is a MUST as seats are limited.
1.00pm – Registration 1.30pm to 3.30pm – Workshop starts Peter & Mary Fu Auditorium National Cancer Centre Singapore 11 Hospital Drive Singapore 169610
PHONE REGISTRATION ONLY Please call: 6225 5655 Monday – Friday: 8.30am to 5.30pm
The information is correct at Press time. NCCS reserves the right to change programmes or speaker without prior notice.
SALUBRIS APRIL – JUNE 2015
SEMINARS / FORUMS / TUMOUR BOARDS / SMC-CME ACTIVITIES FOR MEDICAL PROFESSIONALS ONLY
MAY 2015 Date
Time
Event Information
CME Pt
Lung Tumour Board Combine SGH-NCCS Meeting 7, 14, 21, 28
11.30 am
@ SGH Blk 2 Level 1, Radiology Conference Room
1
Christina Lee Siok Cheng 6326 6095 christina.lee.s.c@nhc.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
NCCS-SGH Joint Lymphoma Workgroup Meeting 7, 21
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Registration Contact
NCCS Tumour Board Meetings:
Lim Shufen / Ella 6436 8283 / 6436 8294 dsolsf@nccs.com.sg / Nursuhaila.rahmat @ nccs.com.sg
6, 13, 20, 27
4.30 pm
Sarcoma Tumour Board Meeting
1
6, 13, 20, 27
5.00 pm
Surgical Oncology Tumour Board Meeting
1
4, 11, 18, 25
5.00 pm
Head & Neck Tumour Board Meeting
1
Daphne 6436 8592 pakiam.marie.daphne@nccs.com.sg
1
Evelyn Loy 6236 9495 evelyn.loy.t.h@nccs.com.sg
1
Saratha / Ang Hui Lan 6436 8165 / 6436 8174 saratha.v.gopal@nccs.com.sg / dmoahl@nccs.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
1
Carol Tang / Ang Hui Lan 6436 8539 / 6436 8174 nnotwc@nccs.com.sg / dmoahl@nccs.com.sg
1
Phua Chay Sin 6704 2037 ddipcs@nccs.com.sg
1
Phua Chay Sin 6704 2037 ddipcs@nccs.com.sg
@ NCCS Level 2, Clinic C, Discussion Room S’Health Hepato-Pancreato-Biliary Tumour Board 6, 13, 20, 27
1.00 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium NCCS Neuro Onco Tumour Board Meeting
26
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Endocrine and Rare Tumour Meeting 28
7.30 am
@ NCCS Level 2, Clinic C, Discussion Room Upper GI Tumour Board Meeting
14, 28
12.30 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium
Journal Club 15
1.00 pm
Topic: To be advised @ NCCS Level 1, Mammo Suite Discussion Room Teaching Session
22
1.00 pm
Topic : To be advised @ NCCS Level 1, Mammo Suite Discussion Room
17
18
SALUBRIS APRIL – JUNE 2015
SEMINARS / FORUMS / TUMOUR BOARDS / SMC-CME ACTIVITIES FOR MEDICAL PROFESSIONALS ONLY
JUNE 2015 Date
Time
Event Information
CME Pt
S’Health Hepato-Pancreato-Biliary Tumour Board 3, 10, 17, 24
1.00 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium
1
NCCS Tumour Board Meetings:
Registration Contact Evelyn Loy 6236 9495 evelyn.loy.t.h@nccs.com.sg
Lim Shufen / Ella 6436 8283 / 6436 8294 dsolsf@nccs.com.sg / Nursuhaila.rahmat@nccs.com.sg
3, 10, 17, 24
4.30 pm
Sarcoma Tumour Board Meeting
1
3, 10, 17, 24
5.00 pm
Surgical Oncology Tumour Board Meeting
1
8, 15, 22, 29
5.00 pm
Head & Neck Tumour Board Meeting
1
Daphne 6436 8295 pakiam.marie.daphne@nccs.com.sg
1
Christina Lee Siok Cheng 6326 6095 christina.lee.s.c@nhc.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
1
Saratha / Ang Hui Lan 6436 8165 / 6436 8174 saratha.v.gopal@nccs.com.sg / dmoahl@nccs.com.sg
1
Carol Tang / Ang Hui Lan 6436 8539 / 6436 8174 nnotwc@nccs.com.sg / dmoahl@nccs.com.sg
@ NCCS Level 2, Clinic C, Discussion Room
Lung Tumour Board Combine SGH-NCCS Meeting 4, 11, 18, 25
11.30 am
@ SGH Blk 2 Level 1, Radiology Conference Room
NCCS-SGH Joint Lymphoma Workgroup Meeting 4, 18
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Endocrine and Rare Tumour Meeting 25
7.30 am
@ NCCS Level 2, Clinic C, Discussion Room
NCCS Neuro Onco Tumour Board Meeting 23
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Upper GI Tumour Board Meeting 11, 25
12.30 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium
SALUBRIS APRIL – JUNE 2015
SEMINARS / FORUMS / TUMOUR BOARDS / SMC-CME ACTIVITIES FOR MEDICAL PROFESSIONALS ONLY
JULY 2015 Date
Time
Event Information
CME Pt
Lung Tumour Board Combine SGH-NCCS Meeting 2, 9, 16, 23, 30
11.30 am
@ SGH Blk 2 Level 1, Radiology Conference Room
1
Christina Lee Siok Cheng 6326 6095 christina.lee.s.c@nhc.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
NCCS-SGH Joint Lymphoma Workgroup Meeting 2, 16
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Registration Contact
NCCS Tumour Board Meetings:
Lim Shufen / Ella 6436 8283 / 6436 8294 dsolsf@nccs.com.sg / Nursuhaila.rahmat@nccs.com.sg
1, 8, 15, 22, 29
4.30 pm
Sarcoma Tumour Board Meeting
1
1, 8, 15, 22, 29
5.00 pm
Surgical Oncology Tumour Board Meeting
1
6, 13, 20, 27
5.00 pm
Head & Neck Tumour Board Meeting
1
Daphne 6436 8592 pakiam.marie.daphne@nccs.com.sg
1
Evelyn Loy 6236 9495 evelyn.loy.t.h@nccs.com.sg
1
Saratha / Ang Hui Lan 6436 8165 / 6436 8174 saratha.v.gopal@nccs.com.sg / dmoahl@nccs.com.sg
1
Jennie Tan 6436 8280 jennie.tan.l.k@nccs.com.sg
1
Carol Tang / Ang Hui Lan 6436 8539 / 6436 8174 nnotwc@nccs.com.sg / dmoahl@nccs.com.sg
1
Phua Chay Sin 6704 2037 ddipcs@nccs.com.sg
1
Phua Chay Sin 6704 2037 ddipcs@nccs.com.sg
@ NCCS Level 2, Clinic C, Discussion Room S’Health Hepato-Pancreato-Biliary Tumour Board 1, 8, 15, 22, 29
1.00 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium NCCS Neuro Onco Tumour Board Meeting
28
5.00 pm
@ NCCS Level 2, Clinic C, Discussion Room
Endocrine and Rare Tumour Meeting 30
7.30 am
@ NCCS Level 2, Clinic C, Discussion Room
Upper GI Tumour Board Meeting 9, 23
12.30 pm
@ NCCS Level 4, Peter & Mary Fu Auditorium
Journal Club PH
1.00 pm
Topic: To be advised @ NCCS Level 1, Mammo Suite Discussion Room Teaching Session
24
1.00 pm
Topic: To be advised @ NCCS Level 1, Mammo Suite Discussion Room
19
20
SALUBRIS APRIL – JUNE 2015
Reflections of
LEE KUAN YEW
1 9 2 3 – 2 0 1 5
We Remember with Gratitude
W
e in NCCS are greatly saddened by the passing of Mr Lee Kuan Yew, our founding father of Singapore. There are so many things that he and his team have put in place for Singapore that have benefitted us as care-givers and our patients, the cancer sufferers. His acute sense of vulnerability, his indomitable spirit, his measures to put in good governance and his insistence on excellence and finally his recognition of the importance of human talent are all important life lessons and resonate so well with us in the cancer community as we grapple with the life and death struggles of our patients. As the director of NCCS, as we plan for the new building and the acquiring of proton technology in cancer treatment, we will be guided by these words from Mr Lee: “The task of the leaders must be to provide or create for them a strong framework within which they can learn, work hard, be productive and be rewarded accordingly. And this is not easy to achieve.” From
Prof Soo Khee Chee Director, NCCS
I
n my National Cancer Centre Singapore (NCCS) outpatient clinic three days after the passing of Singapore’s Founding Father, Lee Kuan Yew, the mood among the clinic staff was sombre. My Indian nurse Santhy recalled how her father would make his wife and three daughters stand up in the living room of their Lower Delta Road flat, the whole family saluting and singing the National Anthem every 9th August as the National Anthem played on TV during the National Day Parade celebrations. Formerly from the British Army, her father had always been grateful to Mr Lee for creating a better life for him and his family. He later became a long-serving grassroot volunteer in Tanjong Pagar. My Indonesian clinic nurse Zulfa, a cancer patient herself, expressed her sense of emptiness. She said her final goodbye along the street as the funeral cortege passed by on 29th March 2015. Mr Lee’s vision and determination for a multiracial and meritocratic society was a noble ideal and now a vital reality in Singapore. This appreciation runs deeper as I have studied, trained and lived abroad for over 10 years. While this is still a work in progress, racial harmony and opportunity for all must remain a powerful narrative in the Singapore Story. And of course there is our world class healthcare. A cheerful 90 year old patient then came into my clinic in a wheelchair, accompanied by one of her sons. A lovely lady, she shared with us, her voice wavering with sadness, that she was a childhood friend of Mr Lee and his siblings. With her remarkably sharp mind, elephant memory and bubbly personality, she said that when they were young, she found Mr Lee much more intense and serious than his other brothers, who, she chimed, were more fun and friendly. Then she winked and chuckled, “It’s because Harry went to Raffles instead of ACS!” She waxed lyrical of his lightning intellect, his never-say-die spirit and deep dedication to nation building. Finally she said, “Lee Kuan Yew is God’s gift to Singapore. Singapore is truly Harry’s baby.” From
Dr Toh Han Chong Deputy Director, NCCS Senior Consultant, Division of Medical Oncology
PUBLISHED BY NCCS CORPORATE COMMUNICATIONS Editorial Advisors
Medical Editor
Members, Editorial Board
Prof Kon Oi Lian Prof Soo Khee Chee Dr Tan Hiang Khoon
Dr Richard Yeo
Ms Lita Chew Dr Mohd Farid Ms Sharon Leow Ms Jenna Teo Dr Melissa Teo Dr Teo Tze Hern
Editorial Consultant Mr Sunny Wee
Executive Editors Ms Rachel Tan Mr Edwin Yong
SALUBRIS
is produced with you in mind. If there are other topics related to cancer that you would like to read about or if you would like to provide some feedback on the articles covered, please email to corporate@nccs.com.sg.
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