MCQs Revision Biochemistry for NEET Part –II Jan - 2018
DR. SMILY PRUTHI PAHWA (MD-BIOCHEMISTRY) See video on Youtube………. By Tulip academy of Medical sciences Or See video in mobile app – Search on play store : Tulip Academy Website : www.tamsmed.com
Q1. Defect in alpha oxidation of fatty acid leads to : a) Refsum’s disease b) Jamaican Vomiting Sickness c) Zellweger syndrome d) Dicarboxylic aciduria
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Q1. Defect in alpha oxidation of fatty acid leads to : a) Refsum’s disease b) Jamaican Vomiting Sickness c) Zellweger syndrome d) Dicarboxylic aciduria
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Defect in Peroxisomes Defect in alpha oxidation
Defect in oxidation of VLCFA
Zellweger syndrome
Refsum’s disease
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Jamaican Vomiting Sickness • • • • • •
Unripe fruit of akee tree Hypoglycin Inhibits Fatty Acyl CoA Dehydrogenase Severe hypoglycemia after ingestion Sudden vomiting 2-6 hours after ingestion Convulsions, coma & death
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Alpha – oxidation • • • •
Peroxisomes & ER For branched chain FA Removal of 1 carbon from alpha carbon atom No ATPs produced Refsum’s disease – • Defect in alpha oxidation in peroxisomes • Phytanic acid not oxidized • Restrict dairy products & green leafy vegetables Website : www.tamsmed.com
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Q2. A tRNA molecule that is supposed to carry cysteine (tRNAcys) is mischarged. so that it actually carries alanine (ala-tRNAcys). Assuming no correction occurs, what will be the fate of this alanine residue during protein synthesis? A. It will be incorporated into a protein in response to an alanine codon. B. It will be incorporated into a protein in response to a cysteine codon. C. It will remain attached to the tRNA as it cannot be used for protein synthesis. D. It will be chemically converted to cysteine by cellularenzymes. Website : www.tamsmed.com
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Q2. A tRNA molecule that is supposed to carry cysteine (tRNAcys) is mischarged. so that it actually carries alanine (ala-tRNAcys). Assuming no correction occurs, what will be the fate of this alanine residue during protein synthesis? A. It will be incorporated into a protein in response to an alanine codon. B. It will be incorporated into a protein in response to a cysteine codon. C. It will remain attached to the tRNA as it cannot be used for protein synthesis. D. It will be chemically converted to cysteine by cellularenzymes. Website : www.tamsmed.com
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Q3. The hydrolytic step leading to the release of a polypeptide chain from a ribosome is catalyzed by which of the following? a. Dissociation of ribosomes b. Peptidyl transferase c. Release factors d. Stop codons
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Q3. The hydrolytic step leading to the release of a polypeptide chain from a ribosome is catalyzed by which of the following? a. Dissociation of ribosomes b. Peptidyl transferase c. Release factors d. Stop codons
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Q4. What is the importance of lactic acid production in glycolysis? A. Regeneration of NAD B. Regeneration of NADH C. Synthesis of ATP D. Exergonic reaction
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Q4. What is the importance of lactic acid production in glycolysis? A. Regeneration of NAD B. Regeneration of NADH C. Synthesis of ATP D. Exergonic reaction
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Q5. The given is the structure of protein. Which bond is responsible for this structure? a) Disulfide bond b) Hydrophobic bond c) Hydrogen bond d) Covalent bond
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Q5. The given is the structure of protein. Which bond is responsible for this structure? a) Disulfide bond b) Hydrophobic bond c) Hydrogen bond d) Covalent bond
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Q6. Which of the following is true about ketone bodies a. Acetoacetate is most common ketone body present in blood b. Beta hydroxybutyrate is the first ketone body to be synthesized c. Thiophorase is absent in liver d. Muscle can not utilize ketone bodies
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Q6. Which of the following is true about ketone bodies a. Acetoacetate is most common ketone body present in blood b. Beta hydroxybutyrate is the first ketone body to be synthesized c. Thiophorase is absent in liver d. Muscle can not utilize ketone bodies
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Q7. Which one of the following tissues can metabolize glucose, fatty acids, and ketone bodies for ATP production? a. Liver b. Muscle c. Brain d. Red blood cells
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Q7. Which one of the following tissues can metabolize glucose, fatty acids, and ketone bodies for ATP production? a. Liver b. Muscle c. Brain d. Red blood cells
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Q8. All of the following Lipoproteins are increased in type 3 Hyperlipoproteinemia, EXCEPT : a. VLDL Remnant b. Chylomicron remnant c. Triglycerides d. IDL (Intermediate density lipoprotein)
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Q8. All of the following Lipoproteins are increased in type 3 Hyperlipoproteinemia, EXCEPT : a. VLDL Remnant b. Chylomicron remnant c. Triglycerides d. IDL (Intermediate density lipoprotein)
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Q9. HDL is synthesized and secreted from : a. Liver b. Peripheral tissue c. Adipose tissue d. Muscle
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Q9. HDL is synthesized and secreted from : a. Liver b. Peripheral tissue c. Adipose tissue d. Muscle
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Q10. The base sequence of the strand of DNA used as the template for transcription has the base sequence GATCTAC. What is the base sequence of RNA product? a. CTAGATG b. GTAGATC c. GAUCUAC d. GUAGAUC
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Q10. The base sequence of the strand of DNA used as the template for transcription has the base sequence GATCTAC. What is the base sequence of RNA product? a. CTAGATG b. GTAGATC c. GAUCUAC d. GUAGAUC
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