Cancer and Molecular Therapies Prof. Uri Ben-David

Cancer aneuploidy

Healthy human cells have 23 pairs of chromosomes

Any deviation from this number – known as aneuploidy – has very severe consequences For example, an extra copy of chromosome 21 results in Down syndrome. However, cancer cells are highly aneuploid, and aneuploidy is even required for tumor https://www.bendavidlab.com/ progression. Dr. BenDavid studies this "aneuploidy paradox" using state-of-the-art genomic and functional approaches. The work in the lab aims to uncover the basic biology underlying this hallmark of cancer, and to exploit it to target cancer cells and eliminate tumors.

Prof. Ben-David, Department of Human Molecular Genetics and Biochemistry at the School of Medicine, completed his PhD at the Hebrew University and his postdoctoral training at the Broad Institute of Harvard and MIT. Prof. Ben-David is a principal investigator at the Department of Human Molecular Genetics and Biochemistry at the School of Medicine. He completed his PhD at the Hebrew University and his postdoctoral training at the Broad Institute of Harvard and MIT. He was selected as a "Next Generation Star" of the American Association for Cancer Research (AACR). He has earned several prestigious prizes for early-career scientists, including 2021 Cells “Young Investigator of the Year” Award and the 2022 “Krill Award” by the Wolf Foundation. He is a recipient of the ERC Starting Grant. At the TAU Board of Governor’s in May 2023, he will be awarded the Kadar Family Award for Outstanding Research.