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Development, Aging and Regeneration
Prof. Ruth Ashery-Padan
Prof. Ashery-Padan is at the Department of Human Molecular Genetics and Biochemistry, a member of the Sagol School of Neuroscience and holds the Zucker–Sussman Chair for Glaucoma Research.
Development of visual system in mammals
Prof. Ashery-Padan's research group focuses on understanding the molecular mechanisms that control the development of the visual system in mammals The group established and employs transgenic mouse lines for state-of-the-art functional studies of genes in vivo. This is combined with gene-expression profiles using laser capture and single-cell sequencing, transcription https://asherypadanlab.com/ factor activity on target genes, and chromatin structure during development. Her group studies ocular cell types generated from human stem cells to uncover the molecular mechanisms underlying the differentiation of human lineages, and to model human diseases. The work is contributing to understanding the etiology of monogenic and complex retinal diseases, toward a better prediction of individuals' susceptibility and the design of stem cell-based models and future therapies for blinding diseases.
Ashery-Padan completed her MSc and PhD at the Hebrew University of Jerusalem and her postdoctoral training at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany. She is the recipient of the Alon Fellowship (VATAT), the Dan David Prize for Young Investigators, Teva Prize, and the E. Matilda Ziegler Foundation for the Blind Award. Prof. AsheryPadan heads the Yoran Institute for Human Genome Research.
Cytoarchitecture of the mature mouse retina - subset of retinal cell types are identified by immunostaining.
Shaul
Raviv, Ashery-Padan