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COVER STORY: SKINCEUTICALS P-TIOX
P-TIOX: SkinCeuticals Synergistic Peptide Technology Redefines Wrinkle Correction
Hear from DR STEVEN LIEW on their impressive case study results.
Peptides have signalled a new era in cosmeceutical skincare since gaining notoriety in the early 2000’s. These short chain amino acids are considered master messengers, which can be structured in a multitude of ways to mimic various biological processes in the body and skin, including maintaining hydration to promoting collagen synthesis. The lightspeed trending of skincare on social media, accompanied with a desire for more non-invasive, anti-ageing treatments has seen many brands incorporate peptides in their products.
As the number #1 medical aesthetic brand worldwide, SkinCeuticals prides itself on being at the forefront of skincare innovation. P-TIOX, SkinCeuticals latest
anti-ageing formula is a testament to this innovation, integrating advancements in peptide technology, alongside a radiant skin complexion to correct the appearance of contraction lines and improve skin quality.
P-TIOX features an ‘Advanced Peptide Complex’, a potent combination of two clinically proven peptides that work in tandem to relax superficial muscle contraction, softening the appearance of expression lines, including those that cannot be treated with neurotoxin injectables.
Powerful ingredients
Acetyl Hexapeptide-8 is a synthetic peptide that reduces the amount of neurotransmitter released at the neuromuscular junction, therefore relaxing the superficial facial muscles that, with repeated action, lead to the formation of wrinkles and fine lines. Numerous independent, clinical studies have demonstrated the efficacy of Acetyl Hexapeptide-8, which is well tolerated by a variety of skin types, even those with the most sensitive skin. Additionally, this peptide provides benefits as a humectant where it supports skin barrier health.
The wrinkle-reducing ability of P-TIOX is further amplified by the 2% Dipeptide Diaminobutyroyl. This peptide mimics the mechanism of viper snake venom that relaxes muscles by blocking neurotransmitter binding on the muscle membrane. This innovative peptide works in synergy with Acetyl Hexapeptide-8, targeting different pathways of muscle contraction for a comprehensive approach to smoothing facial expression lines by up to 20% after 12 weeks of use.
P-TIOX is truly a serum that creates a smoother, firmer and glowing skin that is noticeable within a few short weeks
– Dr Steven Liew
P-TIOX goes beyond addressing wrinkles, targeting multiple facets of skin ageing to deliver a much sought after skin radiance. This multifaceted approach stems from the brand’s deep understanding of skin ageing mechanisms and formulation science, recognising that youthful skin is about more than just wrinkle reduction. P-TIOX incorporates a ‘Radiant Skin Complex’ comprising 5% Poly-Hydroxy Acid (PHA), 5% Niacinamide, and 1% Laminaria Extract. This potent blend refines texture, minimises pores, improves skin tone, and infuses skin with a healthy, luminous glow.
The efficaciousness of P-TIOX does not just stem from individual ingredient benefits, rather the unique formulation maximises synergy between the active ingredients. Ex-vivo studies on human skin have shown that this specific ingredient combination significantly outperforms the use of a single peptide in boosting the expression of eight crucial biomarkers associated with youthful skin, including collagen I and IV. This translates to amplified results meaning smoother texture, reduced wrinkles, and a fresh, youthful complexion.
12-week case study results
Earlier this year, dermatologist Dr Cara McDonald and specialist plastic surgeon Dr Steven Liew, participated in a global advisory board on P-TIOX. They were tasked with selecting 2 patients each to trial P-TIOX as part of a 12-week case study, where all other skincare actives were stopped, with only P-TIOX and an SPF used.
My patients have reported noticeable improvements in skin firmness and texture within just a few weeks of use of P-TIOX
– Dr Cara McDonald
All patients reported significant improvements in the appearance of their lines and wrinkles, with Dr McDonald confirming “my patients have reported noticeable improvements in skin firmness and texture within just a few weeks of use of P-TIOX. The serum’s lightweight formula absorbs quickly, and is suitable for all skin types, including sensitive skin.” Dr McDonald believes these results stem from the fact that “the unique combination of ingredients not only target muscles in the skin but promote collagen production and support the skin’s barrier function, to improve the appearance of wrinkles and other signs of ageing.”
Dr Liew’s case study patients also demonstrated visible improvement in skin quality, texture, and redness, with additional improvements in fine lines especially in the under-eye area. P-TIOX has also become a staple in Dr Liew’s personal skincare routine as “P-TIOX is truly a serum that creates a smoother, firmer and glowing skin that is noticeable within a few short weeks. It is backed by robust scientific studies. I cannot wait to see its long-term benefit beyond 12 weeks of use.”
Whether used as monotherapy or integrated in a regimen alongside in-clinic procedures, P-TIOX offers a powerful solution for those seeking to address visible signs of ageing. By combining the wrinkle-relaxing benefits of advanced peptides with the radiance-boosting and texturerefining properties the ‘Radiant Skin Complex’, P-TIOX allows patients to achieve their skincare goals for healthier more youthful-looking skin.
