Parade 02-12 by The Southern Illinoisan

S U N D AY, F E B R U A RY 1 2 , 2 0 1 2

Science of Love

The

What new research can teach us about romance—and how to make it last

PARADE

OF MU D THE SIC NIG SCE ’ HT AT P S BIGG NES EST A R /GR A AMM DE.CO M YS

celebrity Parade.com/celebrity

and ﬁnd inspiration fo for their lyrics in literature literature. Lead singer Mumford, who’s engaged to actre actress e Carey Mulligan, even runs a book club on th the band’s website; check it out at mumford andsons.com. andsons. s.com.

P Beyoncé

Q: Beyoncé has recorded songs in Spanish. Does she speak the language?

best comedy album—will host a prime-time talk show, Kathy, on the network in the spring. Read more at Parade.com/grifﬁn.

—Doreen Afful, Baltimore

A: Though the singer

and new mom, 30, studied Spanish in school, she doesn’t speak it. “It’s actually way easier for me to sing in another language than speak because it has a melody to it,” she said in 2007, when she released a version of her album B’day that featured six tunes in Spanish. She learns foreign-language songs phonetically, practicing sentence by sentence.

P Kathy Griffin

Is it true that Katy Perry is the daughter of two Christian pastors? P Trace Adkins

WALTER SCOTT ASKS …

Cee Lo Green

The musician and star of The Voice, 37, is in the running in three categories, including Best Pop Vocal Album, at tonight’s Grammy Awards (CBS, 8 p.m. ET). Who are your fashion inﬂuences? I’m inspired by Kiss,

Alice Cooper, Sly Stone, and Elton John—people who have great showmanship. I just like to shake things up and breathe some fresh air back into music. Who’s your biggest competition on The Voice this season?

P Mumford & Sons

Q: What can you tell me about the Grammynominated band Mumford & Sons? —Andrea Thompson, Los Alamitos, Calif.

A: The British group

(above, from left, Ted Dwane, Ben Lovett, Marcus Mumford, and Winston Marshall) came together in 2007

—Paul Rubens, Bloomington, Ind.

I don’t really look at my fellow coaches as competition because we’re all completely different. I’d love to trade places with Christina [Aguilera] to see what it feels like to sing as brilliantly as she does. Blake [Shelton] is down-to-earth, charming, witty, charismatic. I’ve grown very fond of him. And Adam [Levine] and I are friends, too. He’s just supercool. Email your What is your Twitter philosophy? Somequestions to times less is more! I make sure that Walter Scott at Parade.com it’s signiﬁcant and ﬁlled with a sense of humor. I’m a people person, so it comes /contact easily to me. It’s my passion. Letters to Walter Scott can be sent to P.O. Box 5001, Grand Central Station, New York, N.Y. 10163-5001

Q: Would Trace Adkins ever appear on a reality show again? —Anonymous

A: The 50-year-old

country star and runnerup on The Celebrity Apprentice, whose Songs & Stories tour kicks off in March, says the construction of his family’s new home (their last one burned down in June) may be documented for TV. “It’s something my wife wants to do,” he says. Q: What happened to

Kathy Grifﬁn’s My Life on the D-List? —Sandra Friedli, Lacey, Wash.

A: Grifﬁn, 51, and Bravo

wrapped that series up in early 2011. But the star— a Grammy nominee for

Yes; the singer’s parents, Keith and Mary Hudson, are both evangelical ministers who travel the country delivering their sermons.

PHOTOS, CLOCKWISE FROM BOTTOM LEFT: TIBOR BOZI/CORBIS; JIM SPELLMAN/WIREIMAGE; JEFFREY MAYER/WIREIMAGE; DIMITRIOS KAMBOURIS/WIREIMAGE FOR OUT; C. FLANIGAN/FILMMAGIC; STEVEN LAWTON/FILMMAGIC

Walter Scott,s

GR AWAMM Spe AR Y cial DS Edi GO tion BEH IN

2 • February 12, 2012

HEARING TECHNOLOGY UPDATE

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year you’ll buy a new car? That’s what auto industry execs are hoping— and they have reason to be optimistic. Though the economy is still ailing, vehicle sales rose 10 percent last year, in part because people who had held on to their cars far longer than

usual were ready to upgrade. To meet pent-up demand, Toyota is rolling out a Prius subcompact, and Honda has introduced a Civic that runs on natural gas. But the biggest news may be that a resurgent Detroit has gone green to appeal to consumer tastes, which are trending toward smaller cars with more

ffuel-effi fuel fu uel el-e -effi -e fficient gas engines and eventually hybrids and plug-ins. Those in the market for a new set of wheel wheels can get revved up at the Chicago Auto Show, the country’s largest consumer showcase. Highlights include the lightest, most fuel-efficient Cadillac, the

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ATS; A TS; the 22013 Dodge Dart, aggressively aggre priced at $16,000, wit with a glove box designed to h hold an iPad; and, from abroad, abr a diesel VW Beetle co convertible. Though GM remains the largest U.S. automaker, larg Ford is generating lots of buzz. Its big 2012 launch: the Fusion, a sleek midsize sedan in gas, hybrid, and plug-in hybrid models. But even amid all the leanness and improved gas mileage, there’s room for a classic muscle car: The Chicago show is debuting the Mustang Shelby GT500 convertible. Equipped with a supercharged V-8, it’ll be the most powerful Mustang yet. Which could be just enough to get America’s motor running. —Josh Dean

DR. OZ’S Transformation Nation: Million Dollar You

SMART MOVE OF THE WEEK Stress isn’t just a pain in the neck; it can also pack on the pounds. Millennia ago, humans felt stress mainly in the form of hunger. Nature provided systems for storing fat to keep us from starving. The stresses of modern life are different, but the same defense mechanisms apply. To shut off your body’s fatstoring tendency, decompress. Learn transcendental meditation, listen to music, and exercise to raise endorphins. For more video tips from Dr. Oz, go to Parade.com/oz.

Reese Witherspoon, and Tom Hardy star in a slick but satisfying romantic comedy that blends just enough action (CIA pals vie for the same woman, using all their high-tech tools and skills) with enough heart to make it a date-night bonanza.

P Music A DIFFERENT KIND OF TRUTH Van Halen, $14 It’s been almost 30 years since their last album together, but David Lee Roth and Eddie Van Halen can still tear it up. Truth is a welcome throwback to the sound that made the band famous. HOME Dierks Bentley, $17

Bluegrass meets rock on the country star’s stellar new release, a radio-friendly mix of party anthems and introspective ballads. Worth singling out: “When You Gonna Come Around,” a haunting duet with Little Big Town’s Karen Fairchild.

PHOTOS, CLOCKWISE FROM BOTTOM LEFT: SONY PICTURES TELEVISION; COURTESY OF FORD MOTORS; NO CREDIT; KIMBERLEY FRENCH; NO CREDIT

Rated R Chris Pine,

4 • February 12, 2012

Happy & Healthy

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A: It’s the dilemma of every working man and woman, this nagging worry that you’re never in the right place at the right time, that someone—your kids, your colleagues, your spouse— is getting short shrift. You want to make sure the people you work with are comfortable with you, and you don’t want to do anything to jeopardize that or hinder your career. But remember how important this time is to your child and how much he looks forward to seeing Dad. Try this compromise: Make a point of going out with your work buddies once a month, not once a week, for a couple of drinks. The occasional change-up in your routine will be good for both you and your son. Then, get proactive about organizing gatherings. Start one yourself during lunch, outside the conﬁnes of the ofﬁce. You’ll connect with your coworkers without taking time away from your kid. —Judith Newman

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Send your questions to Parade.com/mannerup February 12, 2012 • 5

Produced by Women’s Marketing Inc. 203.256.4132 womensmarketing.com

Sunday with ... I needed to ground myself, to search within. I met my ﬁancé after that dark period, when I was starting to get back my appetite for life. THE GRIEF PROCESS Who’s your fiancé? CHANGES YOU He’s a business FOREVER, AND IT CHANGED analyst. We met at ME FOR THE an after-after-party. It BETTER.” was soul mates at ﬁrst sight—“I feel like I know you.” When you’re not looking, that’s when it happens. It was refreshing for both of us to encounter a grown-up!

on TV—surgeon Callie Torres of the long-running Grey’s Anatomy (ABC, Thursdays, 9 p.m. ET)—engages “the geeky side of my brain,” says Sara Ramirez, 36. But the Mexicanborn actress, who won a 2005 Tony in the stage smash Monty Python’s Spamalot before ﬁnding a wider audience in prime time, also stole the show’s musical episode. Thelma Adams raises the curtain on Ramirez and learns that she’d love to play Evita on Broadway—when she ﬁnally surrenders her scalpel.

What do the two of you do on Sundays? We hike in the canyon near our house. It’s a wonderful way to decompress, a soothing environment in which to talk while we’re walking—unless we’re out of breath. Then there’s laundry, cleaning the house, shopping for food. It’s our day to replenish and check in with each other.

PARADE Callie and her girl-

friend, Arizona, got married on the show last year. What was the response? I’ve gotten tons of positive feedback. We offered up romance that a gay couple could relate to, and that’s very inclusive. I felt honored to tell that story. Which do you prefer, TV or theater? Theater feeds my heart and soul. In TV, the work is a bit more scattered; in the theater you’re in it together from the get-go. You have to be ready to handle any situation at any moment.

Sara Ramirez

Is your biological clock ticking? I’m considering having kids. It’s a huge responsibility to me. I come from a family that’s divorced, and that gives you a sense of caution. I get the timeline, I get the stats, but I want to enjoy being engaged for a minute.

The Grey’s Anatomy star on finding love—onscreen and off you could see half of the hidden gown underneath, so the surprise was ruined—and the audience loved it because of the unplanned joke. We all cracked up together.

Have you ever had a wardrobe malfunction onstage? When I worked with Who is your favorite Tim Curry on SpamaTV doc? See our lot, my costume was a list of the best hospital shows gown hidden beneath of all time at another gown, to be reParade.com/tv vealed later. One night,

What classic musical would you want to do in a revival? Evita! It’s one of my favorites—the music, the drama, this com-

plex character. It’s coming to Broadway [in the spring]. Obviously, I missed that boat. In 2008, your best friend, New York actor Al D. Rodriguez, died from liver cancer. How did you deal with that loss? It was a wake-up call about what’s important in life. The grief process changes you forever, and it changed me for the better.

Was 2011 a peak year for you? It was the ﬁrst year I felt like I was back after my best friend died. I had been in a lot of pain, and angry. I didn’t know if I was ever going to come out of it. Last year I felt lighter, more interested in people. Now I’m walking around going, “Isn’t life great?”

PHOTO: GREG GORMAN

laying a doctor

6 • February 12, 2012

StayHealthy Q: My son, a high school freshman, wants to start drinking coffee in the morning. Wouldn’t that be bad for his health? A: I don’t think it’s a good idea, and he should avoid other super-caff p einated beverages such as energy drinks. Studies have sh shown h that young people are more likely to o suffer from caffeine’s adverse effects, ec like insomnia, headaches, e an n elevated blood pressure. And and h high doses of caffeine are bad for bone health at a crucial time for building the skeleton. Better choices: water or low-fat milk. —Dr. Janet Silverstein, professor of pediatric endocrinology at the U University of Florida

E HOUS CALL

Smart at H Heart

We asked Dr. Steven Nissen and Dr. Marc Gillinov, authors of Heart 411, how to stay out of the cardiologist’s office— and what to do if you’re already there.

PHOTO: ISTOCKPHOTO.COM

Most people know that being overweight or smoking can negatively affect heart health, but what about lesserknown risk factors? There are many, including periodontal disease, migraines, and rheumatoid arthritis. We’re still figuring out how big a role some of these risk factors play, but if you have one, it’s even more important to learn where you stand on the basics, like cholesterol. What about exercise? You always hear about the guy who goes out for a run, then suffers a heart attack. It’s a myth that you

shouldn’t exercise if you’re at risk for heart disease. If you have chest pain or have been diagnosed with heart disease and you want to train for something intensive, you should see your doctor first. But almost anybody can begin a walking program with virtually no risk. Are chocolate and red wine really good for your heart? A small amount of dark chocolate can be part of a healthy diet, but we don’t have any real evidence that it reduces heart disease risk. Alcohol may improve artery health, but it can have negative effects as well, especially if you drink

too much. Consuming these foods won’t cancel out bad lifestyle habits; it’s more important to follow a nutritious diet overall. You devote a chapter to the heart tests that most people need— and don’t need. How can patients avoid being overtested? A lot of people get a test “just to see,” but Americans are exposed to more radiation than people in any other country due to too much medical testing, and that’s a problem. Always ask your doctor, “Will this test make me better off, and how will the result change the way I’m treated?”

THE

SCIENCE of

LOVE

BY J U DI T H N E W M A N

C OV E R A N D OPE N I NG PH O T O I L LUST R AT I ON BY C R A IG C U T L E R

PHOTO CREDITS WILL GO HERE AS SHOWN

RESEARCHERS HAVE BEGUN TO DECODE THE SECRETS OF ATTRACTION— AND HOW TO MAKE IT LAST

00 • Month 00, 2012

COVER AND INSIDE: PROP STYLING, MATTHEW GLEASON. PHOTO, THIS PAGE: WILLIAM LOVELACE/EVENING STANDARD/GETTY IMAGES

The ancient Greeks called it “the madness of the gods”; the author Sherwood Anderson dubbed it “the divine accident of life.” But as it turns out, love is neither madness nor an accident. The more we understand how the brain works, the more it seems we are programmed for love, just as we’re programmed to eat and breathe. On this Valentine’s eve, discover how much we’ve learned about this crazy little thing called love.

It turns out that love truly is a chemical reaction. Researchers using MRIs to look at the brain activity of the smitten have found that an interplay of hormones and neurotransmitters create THE POWER the state we call love. Four compounds— OF CHEMISTRY dopamine, norepinephrine, oxytocin, and serotonin—are likely to be particularly critical, says Helen Fisher, research professor of anthropology at Rutgers University and author of Why We Love: The Nature and Chemistry of Romantic Love. Although the way various chemicals interact in the brain is complex and still largely unknown, data suggests that each plays a different role. ■ Addicted to Love Dopamine, a neurotransmitter, makes you focus on the beloved—and desire more time with him or her. It is central to your brain’s reward circuitry: When you do something highly pleasurable, dopamine is released, effectively telling the brain, Do it one mo’ time. “If you have higher activity of dopamine in the brain, your susceptibility to falling in love may even go up,” Fisher says. “We’ve put over 50 people who were madly in love in the brain scanner [MRI], and one of the brain regions most activated is the area where dopamine is produced, the ventral tegmental area, or VTA.” Just about anything that 1

gives you pleasure will elevate dopamine activity—from eating a box of chocolates to hitting a hole in one. Liquor both lowers inhibitions and may increase dopamine, which is why half the world’s relationships seem to start over a glass of wine. Novel experiences also raise dopamine activity, so if you want to up the chances of falling in love … well, having dinner with a new interest is great, but you might want to try skydiving, too. Dopamine gets released when an addict uses drugs, which explains the feeling of being “addicted” to your partner when you’re falling in love. “Evolutionarily, one of dopamine’s purposes is to help us become attached to each other,” explains Larry Young, of the Center for Behavioral Neuroscience at Emory School of Medicine. In other words, when Bryan Ferry sang “Love Is the Drug,” he was more accurate than he knew. “There is a kind of addiction that occurs when we fall in love,” Young says. ■ The Butterfly Effect Norepinephrine, a stimulant closely related to dopamine, is most likely what gives you the energy for late-night sessions of staring into each other’s eyes. It can produce sleeplessness, elation, loss of appetite, butterflies in the stomach … in short, the whole megillah of nuttiness that comes with romantic love. ■ Obsessing, Much? Serotonin, a neurochemical that creates feelings of calm, is present in lower levels in those experiencing the first blush of love. “This may go a long way toward explaining that state of anxiety and obsessive thinking that characterizes love in its initial phase,” Fisher says. There is unquestionably a relationship between love and emotions like anxiety and fear. C H E M ICA L In 2004, researchers from R E AC T I ON Italy’s University of Pisa reLiz Taylor leased a study that measured and Richard Burton hormonal activity in 24 young people who reported having recently fallen in love. The newly smitten had higher levels of the stress hormone cortisol than their workaday counterparts. The study also found that men in love had less testosterone than their single brethren; women in love, on the other hand, had more. This February 12, 2012 • 9

A recent brain-scan study examined the newly dumped. When subjects stared at photos of the person who rejected them, their scans resembled those of people withdrawing from drugs. So how to ease the pain? “If someone is camping out in your head, treat it as an addiction,” Professor Helen Fisher says. “If you’re trying to give up alcohol, you don’t leave a bottle of vodka on your desk.” —J. N.

Place letters and pictures of your ex in a lockbox; take her number off your cell, her email address out of your contacts, and her IM name off your buddy list.

Exercise. By increasing the stores of dopamine in the brain, you drive up optimism and get renewed hope.

Get a massage and hug your friends. Both increase oxytocin levels.

Do novel things. “Whether it’s travel, new restaurants, new hobbies, or seeing people you haven’t seen in a while,” Fisher says, “novelty signiﬁcantly elevates activity of dopamine in the brain.”

Fortunately for those of us who aren’t Julia Roberts or George Clooney, there is a wide range of tastes and preferences when it comes to appearance. But it SCENTS AND seems that unconsciously there SENSIBILITY are certain characteristics we look for—qualities that, from an evolutionary point of view, bode well for our reproductive health. First and foremost is youth—particularly for men looking at women. No amount of diet, exercise, and Botox can deny that women’s eggs have a certain sell-by date. A study released last year tracked men’s eyes when looking at photos of women and found that their gaze lingered longer on waists and breasts, which may signal fertility, than on faces. Women tend to look for traditional signs of masculinity—distinctive cheekbones and a strong jaw. Still, most of us have had that odd experience of meeting someone who is, objectively, very attractive— and yet we just don’t “feel it.” Sometimes we tell ourselves, “Oh, he didn’t smell right.” We usually don’t mean it literally—but a few scientists believe we may actually be onto something. When we talk about “chemistry,” some theorize we’re talking about pheromones, the chemical messengers said to be exuded by the body to inﬂuence the behavior and mood of others. For decades, scientists have known that insects communicate their sexual receptivity to one another via pheromones. Termites, for example, use them to mark territory or lead members of their swarm to food. The notion that humans also communicate subliminal messages with pheromones has long been

suspected. Some studies have shown that during ovulaThe Duke and tion, women are Duchess of Cambridge more attentive to sexual messages from the outside world, dress more provocatively, and stare more at handsome men. This begs the question: Does a woman’s estrous cycle have a discernible effect on male behavior? Sure enough, in a study done by Saul Miller of the University of Kentucky and Jon Maner of Florida State University, men who interacted with ovulating women and then were asked to play blackjack were found to take more risks, in an attempt to make more money, than the men who’d interacted with non-ovulating women—meaning guys get all hunter-ish and daring in the presence of females who might be able to carry their seed into the next generation. Further, they found that men who smelled the T-shirts of ovulating women had greater levels of testosterone and were more likely to use sexual language than men who smelled the T-shirts of nonovulating women. Nevertheless, pheromones remain controversial in the scientiﬁc community, with many doubting they play any kind of role. In his recent book The Great Pheromone Myth, Richard Doty, director of the Smell and Taste Center at the University of Pennsylvania, concludes that mammalian pheromones do not even exist. What it is about the scents of ovulating women that changes men’s behavior in the MillerManer studies is still unknown. Perhaps not surprisingly, taking birth control pills, which disrupt hormones, plays with these natural inclinations. According to a study at the University of Shefﬁeld in England, women on the pill no longer experience a greater desire during ovulation for traditionally masculine men (good news for the Jonas brothers)—and, the study speculates, men no longer exhibit a higher or lower degree of interest for a woman on the pill based Celebs in lasting marriages on her menstrual cycle. share their secrets at Scent may even play Parade.com/love a role in kissing. Though scientists aren’t sure M AGN E T IC AT T R AC T I ON

continued on page 15

PHOTO: JEFF J. MITCHELL/GETTY IMAGES

THE CURE FOR A BROKEN HEART

lends at least some biological credence to the popular idea that men in love are tamed and women in love are a little wilder and freer. ■ The Urge to Merge Oxytocin is what cements the trust and bond between two people. The neurochemical is released in both men and women when they have sex (women also get a dose when they give birth and breast-feed). It is, says Young, “the hormone of attachment and emotional empathy. Give a person intranasal oxytocin and they’ll look more deeply into the eyes of the person they’re with and report feeling a greater sense of trust.” Young has studied the effects of oxytocin on prairie voles. Here’s the thing about these voles: They aren’t players. They mate for life. Unless ... “If you block their oxytocin receptors, they don’t become bonded to another partner,” he explains. “You can introduce two voles whose receptors are blocked and they can mate all night long, and the next day they don’t care.”

10 • February 12, 2012

a See offer FREE below b .

Today, I took steps to balance my TYPE 2 DIABETES. Today, I chose exercise and talked to my doctor. JANUVIA works to lower blood sugar in 2 ways. Talk to your doctor about JANUVIA today. Increases Insulin

Decreases Sugar Made In Liver

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JANUVIA (jah-NEW-vee-ah) should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inďŹ&#x201A;ammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUVIA. Serious side effects can happen in people who take JANUVIA, including pancreatitis, which may be severe and lead to death. Before you start taking JANUVIA, tell your doctor if youâ&#x20AC;&#x2122;ve ever had pancreatitis. Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis. Do not take JANUVIA if you are allergic to any of its ingredients, including sitagliptin. Symptoms of serious allergic reactions to JANUVIA, including rash, hives, and swelling of the face, lips, tongue, and throat that may cause difďŹ culty breathing or swallowing, can occur. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away. a

Kidney problems, sometimes requiring dialysis, have been reported. If you take JANUVIA with another medicine that can cause low blood sugar (hypoglycemia), such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIA. Signs and symptoms of low blood sugar may include headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heart beat, sweating, and feeling jittery. Your doctor may do blood tests before and during treatment with JANUVIA to see how well your kidneys are working. Based on these results, your doctor may change your dose of JANUVIA. The most common side effects of JANUVIA are upper respiratory tract infection, stuffy or runny nose and sore throat, and headache.

Call 1-888-JANUVIA or visit Januvia.com. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Fingertip Formulary, LLC, June 2011.

Please see the Medication Guide on the next page and discuss it with your doctor. Having trouble paying for your Merck medicine? Merck may be able to help. www.merck.com/merckhelps Copyright ÂŠ 2011 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. All rights reserved. DIAB-1017402-0003 12/11

Terms and conditions apply. Please see next page. Dose _____mg Offer valid for up to 30 tablets.

Eligible patients may receive a free 30-day trial supply of JANUVIA. 1. Take this voucher to your next appointment. Ask your doctor about JANUVIA. 2. Get a free 30-day trial supply of JANUVIA if your doctor says itâ&#x20AC;&#x2122;s right for you. No purchase is required. Not valid for reďŹ lls. JANUVIA is a prescription medication. Only your health care provider can decide if JANUVIA is right for you. How this voucher works: 9 $ " 9 &#! 2+5:;1+

eligible retail pharmacy (certain restrictions apply). 9 &#! 2+5:;1+" 8 " Please see Terms and Conditions on the back of this voucher. Expiration Date: 06/30/2012 Prescriber 9 &#! * Read the Prescribing Information before prescribing JANUVIA. < &# 2+5:;1+" 5 " 8

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RxBIN No: 610524

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ID: 016603445

Medication Guide JANUVIAÂŽ (jah-NEW-vee-ah) (sitagliptin) Tablets Read this Medication Guide carefully before you start taking JANUVIA and each time you get a reďŹ ll. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment. If you have any questions about JANUVIA, ask your doctor or pharmacist. What is the most important information I should know about JANUVIA? Serious side effects can happen in people taking JANUVIA, including inďŹ&#x201A;ammation of the pancreas (pancreatitis) which may be severe and lead to death. Certain medical problems make you more likely to get pancreatitis. Before you start taking JANUVIA: Tell your doctor if you have ever had ) ' * # #+ + (' + #' ( * ! %% % * ! %%+ (' +

"#+ (* ( % ("(%#+& "#!" %(( *#!% *# % %+ $# ' )*( % &+ Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis. What is JANUVIA? JANUVIA is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. #+ '( (* ) ()% # " ) # + JANUVIA is not for people with diabetic ketoacidosis (increased ketones in your blood or urine). If you have had pancreatitis (inďŹ&#x201A;ammation of the pancreas) in the past, it is not known if you have a higher chance of getting pancreatitis while you take JANUVIA. #+ '( $'( ' # #+ + ' # " ' + #' "#% * ' ' * *+ ( ! Who should not take JANUVIA? Do not take JANUVIA if: you are allergic to any of the ingredients in JANUVIA. See the end of this Medication Guide for a complete list of ingredients in JANUVIA. Symptoms of a serious allergic reaction to JANUVIA may include: * +" * #+ * ) " + (' ( * +$#' "# +

swelling of the face, lips, tongue, and throat that may cause difďŹ culty in breathing or swallowing What should I tell my doctor before taking JANUVIA? Before you take JANUVIA, tell your doctor if you: " (* " " #' && #(' ( ( * ) ' * + ) ' * # #+ " $# ' )*( % &+ " ' ( " * & # % (' # #('+ are pregnant or plan to become pregnant. It is not known if JANUVIA will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant. Pregnancy Registry: If you take JANUVIA at any time during your pregnancy, talk with your doctor about how you can join the JANUVIA pregnancy registry. The purpose of this registry is to collect information about the health of you and your ( ' '*(%% #' "#+ * !#+ * %%#'! * * + #'! (* )% ' ( * + #+ '( $'( ' # #%% ) ++ #' ( ( * * + &#%$ %$ # " ( * doctor about the best way to feed your baby if you are taking JANUVIA. Tell your doctor about all the medicines you take, #' % #'! )* + *#) #(' ' '(' )* + *#) #(' & # #' + # &#'+ and herbal supplements. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine. How should I take JANUVIA? $ #& " % + ( * ( (* %%+ ( ( ' $ # " (* # "( (( Your doctor may do blood tests from time to time to see how well your kidneys are working. Your doctor may change your dose of JANUVIA based on the results of your blood tests. Your doctor may tell you to take JANUVIA along with other diabetes medicines. Low blood sugar can happen more often when JANUVIA is taken with certain other diabetes medicines. See â&#x20AC;&#x153;What are the possible side effects of JANUVIA?â&#x20AC;?. If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of JANUVIA at the same time. If you take too much JANUVIA, call your doctor or local Poison Control Center right away. When your body is under some types of stress, such as fever, trauma (such as a car accident), infection or surgery, the amount of diabetes medicine that you need may change. Tell your doctor right away if you have any of these conditions and follow your doctorâ&#x20AC;&#x2122;s instructions. Check your blood sugar as your doctor tells you to. Stay on your prescribed diet and exercise program while taking JANUVIA.

Talk to your doctor about how to prevent, recognize and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and problems you have because of your diabetes. Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your /,35.25)04 What are the possible side effects of JANUVIA? Serious side effects have happened in people taking JANUVIA. See â&#x20AC;&#x153;What is the most important information I should know about JANUVIA?â&#x20AC;?. Low blood sugar (hypoglycemia). If you take JANUVIA with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIA. Signs and symptoms of low blood sugar may include: headache irritability drowsiness hunger weakness fast heart beat dizziness sweating confusion feeling jittery Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away. See â&#x20AC;&#x153;Who should not take JANUVIA?â&#x20AC;?. Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes. Kidney problems, sometimes requiring dialysis The most common side effects of JANUVIA include: upper respiratory infection stuffy or runny nose and sore throat headache JANUVIA may have other side effects, including: stomach upset and diarrhea swelling of the hands or legs, when JANUVIA is used with rosiglitazone (AvandiaÂŽ). Rosiglitazone is another type of diabetes medicine. These are not all the possible side effects of JANUVIA. For more information, ask your doctor or pharmacist. Tell your doctor if you have any side effect that bothers you, is unusual or does not go away. (22 5 7 +5* 57 -57 3,+0*(2 (+ 0*, ()5 80+, ,--,* 8 '5 3( 7,657 80+, ,--,* 8 5 ( How should I store JANUVIA? $ 57, !%& ( 5 5 Keep JANUVIA and all medicines out of the reach of children. General information about the use of JANUVIA Medicines are sometimes prescribed for purposes that are not listed in Medication Guides. Do not use JANUVIA for a condition for which it was not prescribed. Do not give JANUVIA to other people, even if they have the same symptoms you have. It may harm them. This Medication Guide summarizes the most important information about JANUVIA. If you would like to know more information, talk with your doctor. You can ask your doctor or pharmacist for additional information about JANUVIA that is written for health professionals. For more information, go to www.JANUVIA.com 57 *(22 What are the ingredients in JANUVIA? Active ingredient: sitagliptin. Inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate. The tablet ďŹ lm coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and yellow iron oxide. What is type 2 diabetes? Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems. High blood sugar can be lowered by diet and exercise, and by certain medicines when necessary. JANUVIAÂŽ is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. AvandiaÂŽ is a registered trademark of GlaxoSmithKline. 56 70./ ,7*1 $/(76 5/3, 576 ( 8 )80+0(7 5- Merck & Co., Inc. All rights reserved #, 08,+ 6702

Manufactured by: Merck Sharp & Dohme (Italia) S.p.A. &0( 3020( "( 0( (2 %$ "( ,4 !5 This Medication Guide has been approved by the U.S. Food and Drug Administration.

DIAB-1017402-0003 12/11

Terms and Conditions 2

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3 1 ! / 3 1 ! 2 , ! , ! It is illegal to sell, purchase, trade, or counterfeit this voucher. Void if reproduced. Void where prohibited by law, taxed, or restricted. Please read the accompanying Medication Guide and discuss it with your doctor. Also available is the physician Prescribing Information. Expiration Date: 06/30/2012

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By Ben Fong-Torres

The Marrying Man

weekend and had begun to talk seriously, though they agreed there was no hurry. But there was. What a rock journalist learned about love from playing the preacher Right after that musical weekend, Bernadette was diagnosed with leukemia. Randy wanted to let ony and marissa, her know he wouldn’t abandon dressed as Hogwarts her. He showed up at the hospital students, stood with a question for Bernadette. before me, ready to It was a shiny question, set inside say “I do.” The bride and groom a Tiffany box.” had met at a sci-fi convention Some couples tell me they don’t and decided to turn their wedwant religion in their service— ding into a costume party. The or want just a token blessing to guests included Batman and satisfy parents. The truth is, there Robin, Groucho Marx, the always seems to be a spiritual Mad Hatter, and the Queen of presence. The ceremony itself, I Hearts. I was Elvis, in sequined often say, is “an outward token of cape, and, as I’ve done at a halfa sacred union of two hearts.” If dozen weddings, I sang “Can’t this is what they’re signing up Help Falling in Love.” for, then I’m their marrying man. But I’m no Elvis impersonMy record is pretty good: Of the ator; I’m an ordained minister, 30 couples I’ve married, only five and Tony and Marissa’s exchange haven’t lasted. of vows, which took place in Each time I stand with a cou2007 in Berkeley, Calif., was my ple, I feel a mix of honor and re20th as officiant—though it may sponsibility. As Elvis might have have been the wackiest. sung, this is the moment they’ve So what’s the deal? How did waited for, the moment of a lifea former rock journalist who Since then, I have officiated at happyness anyway. On the other time. Sometimes, I’ll spot my once covered Paul McCartney weddings all over the Bay Area, hand, Joan and Juan had such a Dianne in the audience and think and Bonnie Raitt end up presidas well as in New York and New good time on their first date, of our own commitment, 36 years ing over weddings? Accidentally. Orleans—in settings ranging chatting and dishing about and counting. Like me, she loves I became an ordained minister of from idyllic gardens to a karaoke friends they had in being a part of these the Universal Life Church in bar. After more than 30 years, I common, that Joan, weddings and havTHERE 1969 when I was researching a still look forward to every assignseated at a sidewalk ing a backstage pass IS ALWAYS A story. The credentials cost me $3, ment, particularly to hearing how café, literally fell off to one of the most SPIRITUAL and I never expected to actually each couple fell in love. Their her chair laughing. It PRESENCE. THE important, exciting CEREMONY use them. Then, in 1976, my stories become the highlights of was a good omen. events in a close IS A TOKEN OF best friend, Tom, asked me to the ceremonies. And Randy won friend’s life. After A SACRED marry him and his girlfriend. There are first-date disasters, Bernadette’s heart the vows, the photos, UNION OF TWO They wanted a simple, at-home like Faby’s. She told Andrew she with heart. As I told and the beginning of HEARTS. ceremony. With my own newlydidn’t like chick flicks, but he the guests at their the reception, the wed wife, Dianne, serving as heard “cheap flicks” and took her wedding in New couple and I repair witness, they exchanged vows, to The Pursuit of Happyness, where Orleans: “After five months of to another room, where we sign and I was on my way as a partFaby, a fan of action and horror courtship, they had just enjoyed a the marriage certificate. My work time minister. movies, nodded off. They found blissful New Orleans Jazz Fest is done, and I love it. I do.

ILLUSTRATION: BARRY BLITT

14 • February 12, 2012

Science of Love | from page 10

exactly why people kiss, some postulate that it’s a reminder of the intimacy of early feeding experiences; others believe it’s a way of getting close enough to experience a potential partner’s smell. Monogamy, while natural, is not always easy, for which there may be biological reasons. Both sexes have inherited the brain circuitry for deep attachment to a mate. But some scientists believe men are predisposed to procreate with as many females as possible, and LOVE THAT women designed to land the best providers by any LASTS means necessary. If our libidos are giving us one message, our knowledge of medicine is giving us quite another. That’s because marriage, and its presumption of monogamy, may be the key to health. According to the CDC, the married are less likely to smoke or drink heavily than people who are single, divorced, or widowed. Other studies show they also have reduced levels of sexually transmitted diseases and lower rates of suicide. Want to live longer and happier (if chubbier—married men tend to be heavier than single men)? If you like it, put a ring on it. Here’s some cheering news: Though everyone talks about how romance fades after the honeymoon, that isn’t necessarily true. Bianca Acevedo of Cornell Medical College and Arthur Aron of Stony Brook University compared the brain scans of couples who had just fallen in love with those

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of men and women who had been married an average of 21 years and said they were still intensely in love with their spouses. Those in longterm relationships were shown images of their partners, as well as of close friends and neutral acquaintances. Guess what? When subjects saw their beloved’s image, their dopamine-rich VTA lit up like a pinball machine. “The brain scans were similar to those in the ﬁrst blush of love, but there was a difference,” says Acevedo. Recall that the newly in love show low activity in the areas of the brain where serotonin is produced, which means anxiety and obsessive thinking. But those still romantically in love after many years show greater activation in serotonin ® and opiad-rich areas associated with elevated calmness and pleasure. “They’re in the secure phase of love,” Acevedo explains. “They still desire one another, they’re engaged, they experience the intensity—but not the anxiety.” Let’s wish that kind of love to everyone who’s dear to us on this “I should have married a border collie.” Valentine’s Day.

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