Aquamedical contract research facility
is an aquatic research facility for contract challenge trials for the pharmaceutical-, feed- and breeding industries, research institutions and government bodies. VESO Vikan offers standardized challenge models for Atlantic salmon, rainbow trout, seabass and Atlantic cod. Pathogens include viruses, bacteria and parasites. VESO Vikan offers long-term vaccine studies (duration of protection) and field trials conducted under commercial farming conditions. We also focus on safety aspects of veterinary medical products. V I K A N
As a contract research facility, VESO Vikan represents an independent partner, ensuring full confidentiality and customer dedication. VESO Vikan focuses on trial quality systems and strives to maintain the highest ethical profile in all our activities. Our aim is to make the VESO trademark synonymous with uncompromising quality and reliability in fish health research.
Technical descripTion VESO Vikan is a state-of-the-art non-recirculation trial unit lab with advanced registration and surveillance systems. e research facility consists of a wet lab with separate isolates and holding tanks from 8 to 7500 liters. e tank design can be customized to accommodate research needs, including individual light regimes, salinity and temperature. Tank numbers in
2
use varies from 200 to 1000, depending on the nature of the trials. e research facility has two fresh water sources and sea water is drawn from 60 meters depth outside the facility. Incoming water is filtered and UV-treated prior to admittance to the test area. e salinity of the ord water is ~33 ‰. Effluent water is disinfected with chlorine and ozone.
challenge FaciliTy challenge experiments are designed to evaluate the efficacy of vaccines, effects of feeding or genetic resistance profiles against infectious agents. VESO Vikan’s R&D focus is to develop and maintain reliable and clinically relevant challenge models for pathogens affecting global aquaculture, especially Salmonids. VESO Vikan’s highly qualified and experienced staff works in
close collaboration with research institutions and the aquaculture industry. We subcontract expertise and services on behalf of our customers when necessary to ensure full width documentation of test products and compliance with formal test requirements. We are happy to develop new models and standards in collaboration with our clients.
FISh
InFEcTIOUS agEnT
DISEaSE
atlantic salmon
Aeromonas salmonicida Vibrio anguillarum o1/o2a Vibrio ordalii Moritella viscosa Piscirickettsia salmonis piscine reovirus (prV) piscine myocarditis virus (pMcV) infectious pancreatic necrosis virus (ipnV) infectious salmon anemia virus (isaV) salmon pancreas disease virus (spdV) Lepeophtheirus salmonis
Furunculosis Vibriosis Vibriosis Winter ulcers salmon rickettsial syndrome (srs) heart and skeletal muscle inflammation (hsMi) cardiomyopathy syndrome (cMs) infectious pancreatic necrosis (ipn) infectious salmon anemia (isa) pancreas disease (pd) sea lice infection
rainbow Aeromonas salmonicida trout Vibrio anguillarum o1/o2a infectious pancreatic necrosis virus (ipnV)
Furunculosis Vibriosis infectious pancreatic necrosis (ipn)
atlantic cod
Vibrio anguillarum o1/o2a/o2b Francisella sp.
Vibriosis Francisellosis
sea bass
Vibrio anguillarum Photobacterium damselae
Vibriosis pasteurellosis
3
ground Floor
4
FirsT Floor
haTchery Salmon for experimental trials in the laboratory and field are produced at VESO Vikan’s hatchery. Production of our own salmon ensures quality in every step from egg to seaworthy smolts. e hatchery produces atlantic salmon (15–30 grams) all year round, including salmon genetically bred for high or low resistance against disease. Our fish are screened and certified pathogen free before being used in trials.
second Floor
Field Trials VESO Vikan holds two salmon farming licenses for R&D. e licenses enable trial conduct under commercial farming conditions throughout the salmon life cycle from hatching to harvest. Fish that are included in field trials are produced at VESO Vikan hatchery. e key application for this composite trial system is to enable evaluation of efficacy and side effects of vaccines in a real-life environment and to facilitate clinical validation of our laboratory challenge models. VESO Vikan has considerable experience in administering field trials and provides administrative and scientific services for fullscale testing of vaccines and pharmaceuticals. Trials are routinely conducted according to gcP (good clinical Practice).
5
QualiTy assurance VESO Vikan is certified according to gLP (good Laboratory Practice) by e norwegian accreditation agency and holds a manufacturing license for medicinal products granted by the norwegian Medicines agency according to gMP (good Manufacturing Practice) requirements. Trials in the laboratory and field can be performed according to gcP (good clinical Practice). gcP ensures international quality standards for clinical trials under the principles of the International cooperation on harmonization of Technical Requirements for Registration of Veterinary Medicinal Products (VIch). VESO Vikan also offers monitoring services for trials run according to gcP at independent trial locations where we use our experience and dedication to vouch for valid trial conduct.
sTaFF e scientific staff at VESO Vikan comprises fish health biologists, veterinarians and university graduates (Msc or PhD). e technical staff is educated in aquaculture. all employees are trained to conduct trials according to the principles of gLP. good Laboratory Practice.
The Veso organisaTion VESO Vikan is part of the VESO Organisation; Veterinærmedisinsk Oppdragssenter aS (VESO), centre of Veterinary contract Research and commercial Services Ltd., Oslo. VESO was established in 1988 and has over 20 years of experience with veterinary vaccines. VESO consists of VESO Vikan and VESO Pharmacy.
Veso pharMacy VESO Pharmacy was established in 2008 and is co-situated with VESO’s head office at adamstua in Oslo. e pharmacy distributes approved vaccines for animals in norway, in addition to pharmaceuticals and disinfectants. VESO Pharmacy represents a neutral link between vaccine producers and veterinary practitioners, aiming to provide the best possible service to both parties.
6
aVs chile (noFiMa, Veso and sinTeF) aVS chile was established in august 2007 as a collaboration between akvaforsk (nofima), VESO and SInTEF Fisheries and aquaculture. e main objective of aVS chile is to develop and make accessible scientific and technological knowledge for the complete aquaculture value chain in chile. aVS chile covers a wide range of scientific competences in feed and nutrition, genetics and reproduction, health management and
vaccination, animal welfare, farming technology and engineering and final product processing and quality. aVS chile aims to create knowledge for a profitable, healthy and sustainable aquaculture industry, as well as to promote the interchange of knowledge in aquaculture between chile and norway. www.avs-chile.cl
7
Trio Media 09/12
VESO Vikan Vikan, N-7800 Namsos Telephone: +47 74 21 77 70 Telefax: +47 74 21 77 71 www.veso.no/veso-vikan VESO Pharmacy & Head Office Ullev책lsveien 68, PO Box 300 Sentrum, N-0103 Oslo Telephone: +47 22 96 11 00 Telefax: +47 22 96 11 11 www.veso.no
www.veso.no