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Catalyst COLLEGE OF CHEMISTRY UNIVERSITY OF CALIFORNIA, BERKELEY dean Charles B. Harris cbharris@berkeley.edu chair, department of chemistry Michael A. Marletta marletta@berkeley.edu chair, department of chemical engineering Jeffrey A. Reimer reimer@berkeley.edu

PUBLICATIONS STAFF assistant dean Jane L. Scheiber 510/642.8782; jscheib@berkeley.edu principal editor Michael Barnes 510/642.6867; m_barnes@berkeley.edu

contributing editor Karen Elliott 510/643.8054; karene@berkeley.edu alumni relations director Camille M. Olufson 510/643.7379; colufson@berkeley.edu

circulation coordinator Dorothy I. Read 510/643.5720; dorothy.read@berkeley.edu design Alissar Rayes Design printing University of California Printing Services

ON THE COVER

These technical graphics illustrate the diversity of research topics covered in this issueâ&#x20AC;&#x2122;s feature stories.

all text and photos by michael barnes unless otherwise noted. for online versions of our publications please see: chemistry.berkeley.edu ÂŠ 2007, College of Chemistry, University of California, Berkeley

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Fall 2 0 0 7 Volume 2 • Issue 2

DEAN’S DESK

COLLEGE OF CHEMISTRY UPDATES

CHEMISTRY NEWS

NEW CHAIRS

CHEMICAL ENGINEERING NEWS

UNIVERSITY UPDATES

FACULTY PROFILE

ALUMNI ASSOCIATION NEWS

ALUMNA PROFILE

CLASS NOTES

IN MEMORIAM

ANNUAL REPORT

10 RAYS OF HOPE

College of Chemistry, UC Berkeley

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It is with some sadness that I announce that this will be my final Catalyst column.

PEG SKORPINSKI

I have decided to step down as the Dean of the College of Chemistry at the end of this calendar year. This was a difficult decision to reach, but I ultimately concluded it was time to return to my work as an active faculty member. Having served the college in an administrative capacity for four and a half years—first as Chair of the Department of Chemistry, and then as Dean of the College — I am ready to focus again on research, teaching, and training graduate students and postdocs. I still find these activities to be an irresistible draw and a source of great personal satisfaction. CHARLES B. HARRIS

Dean and Gilbert N. Lewis Professor

I am, however, very confident that the college continues to thrive, and I am pleased by all we have accomplished. Just in my time as dean, the college has confronted the challenge of finding a way to retain 14 outstanding faculty members in the face of attractive outside offers — 9 of them in chemistry, and 5 in chemical engineering. I am happy to say that 13 of these faculty members have opted to remain at Berkeley, with one case still ongoing. This highly successful retention effort was essential to preserving the excellence of our faculty, and it helps to solidify the college’s international preeminence in the chemical sciences.

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Berkeley National Laboratory and the University of Illinois at Urbana-Champaign. I commend our faculty members who worked so hard to help craft the winning proposal that ultimately secured this unprecedented $500 million award for energy research. More broadly, I am proud of the leadership the college continues to exert in research into many of society’s most pressing problems, including energy, the environment, and health. As an administrator, I have gained an even deeper respect for the numerous staff members who have assisted me in my work. I have benefited greatly from the help and counsel of my senior staff members; they, along with their own excellent teams, have done a superb job overseeing the major business of the college. I will leave my post as dean with the knowledge that the staff’s role is central in sustaining the college’s excellence and well-being. Finally, I have taken great pleasure in getting to know so many of the college’s alumni and friends. Your deep commitment to the college, support of our programs, and involvement in our activities have been an inspiration to me. One of the true joys of serving as dean has been the opportunity to interact with the larger college community and to witness firsthand the loyalty and dedication that so many of you feel — and regularly express — towards our institution. I offer my deepest thanks for your many contributions, which help to make our work both possible and gratifying.

I am also very proud of the University’s success in establishing the Energy Biosciences Institute on our campus, and of the pivotal role the college played in this collaborative effort with Lawrence

Autumn sunlight illuminates the College of Chemistry plaza.

Fall 2007 Catalyst

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Securing our energy and environmental future

Berkeley has established itself as a hub for alternative energy research. The Department of Chemistry is a focal point in the overall initiative. These efforts are centered on what we do best — basic science. Chemistry at Berkeley has long been a home to new and unexpected discoveries that come from intellectually driven students. We hope to turn our students loose with their everpresent level of enthusiasm toward a new and targeted endpoint.

At Berkeley, much of the recent publicity (sometimes even more than the tree people generate) has surrounded the establishment of the Energy Biosciences Institute (EBI). The institute is funded by BP to the tune of 50 million dollars a year for the next 10 years. That’s correct—500 million dollars will be brought to bear on the development of biofuels. A major goal will be to discover the science that will make converting cellulose to useable fuels a financially viable process. The EBI is a joint venture of the Berkeley campus, the Lawrence Berkeley National Laboratory (LBNL) and the University of Illinois. Partnering with Illinois was a key part to winning the international competition. Our collaborators there bring an expertise in crop science and related disciplines that is not represented at LBNL or on the Berkeley campus. The EBI will involve new faculty positions and, of course, students will engage in the research. So the proposed structure and management of the EBI was vetted to the relevant campus oversight committees, and forums were held to allow individual Berkeley faculty members to express their concerns. And express those concerns they did!

College of Chemistry, UC Berkeley

As expected on our campus, a variety of opinions was strongly voiced, but everyone involved sought to ensure freedom of the faculty and students to learn unfettered by the restrictions that might have been imposed by private industry. Many faculty members in the college, and our department in particular, are involved in the EBI, including myself. Biofuels are an important piece of our energy future, but they are only one part of the Berkeley effort. The Helios Project is another important piece. Spearheaded by the strong leadership of LBNL Director Steve Chu, the Helios Project is focused on the conversion of solar energy into carbon-neutral forms of energy with little or no negative environmental impact. Nanoscience and synthetic biology, rapidly expanding areas of science, will be brought to bear on this problem. Berkeley chemists and chemical engineers are central to the Helios Project. Chemistry’s Paul Alivisatos co-directs Helios along with chemical engineering’s Jay Keasling. The development of more efficient photovoltaics, new and efficient catalysts for splitting water into hydrogen and oxygen, and new methods for storing hydrogen will be addressed. To make room for this expanded activity, new buildings will be constructed for both Helios and EBI offices and labs. Berkeley’s Department of Chemistry is fully engaged in trying to secure our energy future, while at the same time it is looking for solutions that will be good for our environment. I am confident that Berkeley chemists and chemical engineers will find

PEG SKORPINSKI

How best to respond to climate change is a hotly debated topic and was even more in the news after the announcement of the 2007 Nobel Peace Prize. Regardless of where you stand on the debate, there are many reasons that the United States and, for that matter, the world, would benefit from alternative sources of energy.

MICHAEL A. MARLETTA Chair, Department of Chemistry, Joel B. Hildebrand Distinguished Professor, and Aldo DeBenedictis Distinguished Professor

solutions to the significant problems ahead. We will be getting help from one of our newest assistant professors, Michelle Chang, who introduces herself below. It is more exciting than ever to be a chemist at Berkeley. by michael marletta

Michelle Chang As an undergraduate student at UC San Diego, I became interested very early on in both chemistry and biology. While looking for a laboratory to get hands-on experience in scientific research, I was fortunate to meet Don Helinski, who bravely accepted a freshman into his group. During my time there, I worked on a project that was centered on understanding horizontal gene transfer in microbial communities from marine sediments. Ten years later, I am still grateful for the opportunity that I had to work with his group, an experience that inspired me to continue in science and apply to graduate school. After graduating from UCSD, I left California for the first time and started my graduate studies at MIT, where I was a joint student with Dan Nocera and JoAnne Stubbe. The focus of my thesis was to investigate the detailed mechanisms of long-range protoncoupled electron transfer in ribonucleotide

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reductase, a complex and physiologically important enzyme. After finishing my Ph.D., I then started my postdoc with Jay Keasling here in the College of Chemistry. The overall goal of my project was to engineer microbes, such as E. coli, to produce a semisynthetic precursor to an antimalarial drug that would be inexpensive enough for developing nations. My experiences with Jay and his laboratory opened my eyes to the opportunities of making an impact at a societal level with basic academic research.

has evolved in microbial hosts to degrade and consume the biopolymers found in plant biomass, with the specific goal of converting lignin to useable liquid transportation fuels. In a second line of research, we are using genetically-engineered cells as a framework to begin studying the complex network of metabolic reactions found in vivo. Using fuel synthesis pathways as a model, we seek to gain a deeper understanding of how biochemical pathways are put together in cells.

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College Awards Seven College of Chemistry faculty members and researchers are the recipients of American Chemical Society awards for 2008:

Jhih-Wei Chu Hewlett-Packard Outstanding Junior Faculty Award funded by HP and sponsored by the ACS Division of Computers in Chemistry.

Graham Fleming Ahmed Zewail Award in Ultrafast Science and Technology sponsored by the Ahmed Zewail Endowment Fund established by Newport Corp. Daniel Neumark Irving Langmuir Award in Chemical Physics sponsored by GE Global Research. Kenneth Raymond ACS Award in Inorganic Chemistry sponsored by Aldrich Chemical Company, Inc. Frantisek Svec ACS Award in Chromatography sponsored by SUPELCO, Inc. 5

Don Tilley Frederick Stanley Kipping Award in Silicon Chemistry sponsored by Dow Corning Corp.

Dean Toste Elias J. Corey Award for Outstanding Original Contribution in Organic Synthesis by a Young Investigator sponsored by the Pfizer Endowment Fund. Chemistryâ&#x20AC;&#x2122;s newest assistant professor, Michelle Chang, is busy setting up her new laboratory.

I joined the faculty at Berkeley as an assistant professor in July 2007, and my group is interested in studying the mechanisms of enzymes that catalyze unique reactions and applying this understanding to build new chemical functions into living cells. Our lab is combining the approaches of enzymology and molecular and cell biology, as well as synthetic biology and metabolic engineering, to address problems in human health and renewable energy. Our current efforts in bioenergy are focused on two fronts. First, we are interested in exploring the specialized chemistry that

Another part of my group is exploring how carbonfluorine bonds can be made enzymatically, with the goal of developing biosynthetic methods to produce fluorinated pharmaceuticals. The ability to selectively substitute fluorine into molecules has been found to be essential for designing new drugs, but remains a challenge using traditional synthetic chemistry. Iâ&#x20AC;&#x2122;m really excited to be starting my independent career here at Berkeley and feel completely welcomed by students, faculty, and staff in the college.

The recipients will be honored at the awards ceremony at the 235th ACS national meeting in April 2008 in New Orleans, LA.

Chu Fleming

Svec

Neumark

Tilley Raymond

Toste

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Thinking holistically about health care The Honda SL100 was hardly a cutting-edge motorcycle; at just over 11 horsepower, the 218-pound bike posted a 0–60 time of about 19 seconds. But it was mine, a 16th-birthday present from my brother. I rebuilt the engine, rejetted the carb, and brought the horsepower to almost 15. But I had forgotten about the transmission. About three miles up an almost dry creek bed (no pun intended) above the Pacific Coast Highway, my rear wheel seized. The painful hours I spent pushing my bike back to Oxnard in the summer heat were a hard lesson on how to think holistically about a system. In the ensuing weeks, I discovered, at great expense, that the extra horsepower I had carefully built into the engine simply overwhelmed the transmission.

This issue of Catalyst tells us about the biomedical research of my colleagues Dave Schaffer and Carolyn Bertozzi. I am humbled by the gifts these colleagues bring to the Berkeley campus. Like my re-built Honda engine, they are providing dramatic additional horsepower for research in the life sciences. Yet even as I admire the potential of their work, I remember my failed motorcycle transmission and I wonder if as researchers we think about our heath care system in a holistic way. Engineers are typically more aware of the need for a good transmission than are other researchers. We understand that unless we can make an invention practical enough for the marketplace, we will not have much effect on society. If a chemical engineer finds a way to improve a catalytic process that makes petrochemical refining cheaper and less polluting, we’re confident such a refinement will rapidly find its way into production. With biomedical discoveries I am not so sure. The conversion of discoveries into practical applications has been complex and slow enough that a few years ago, the National Institutes of Health created a new College of Chemistry, UC Berkeley

initiative to emphasize “translational” research to help speed innovations from “bench to bedside.” But I am still left with some nagging doubts: from bench to whose bedside, and how many bedsides are we talking about? I have no doubt that in the next several years the work of Schaffer, Bertozzi and others who share their dedication will lead to breakthroughs in treating cancer, tuberculosis, Alzheimer’s disease, and many other human maladies. What saddens me is a growing sense that many thousands will suffer and die because they will not have access to these new treatments. The World Health Organization reports that the United States spends more on health care per person than any other nation on the planet. In spite of these costs, a surprising number of U.S. citizens lacks any health care whatsoever (16 percent, according to the Census Bureau). Infant mortality rates (as reported by the United Nations) place the United States 33rd in the world, behind countries such as Cuba, Brunei, Slovenia, Cyprus, and New Caledonia. The U.S. health care system, the transmission that connects biomedical research to our society, is broken. Whether you are conservative or liberal, polls show you are likely to agree. Ultimately, this is not an

JEFFREY A. REIMER Chair, Department of Chemical Engineering, Warren and Katharine Schlinger Distinguished Professor

issue for just the uninsured — it is also a problem for the research community. If the benefits of biomedical research cannot fully reach our citizens, they will begin to question why their tax dollars should support it. I recently had the opportunity to spend a year in Germany, and I can assure you that other industrialized countries deal with health care access in very different ways. Their systems are not perfect, but if you were to ask citizens of Canada, the United Kingdom, Germany or any of the other countries of the European Union if they would choose to swap their health care system for the U.S. version, the answer would almost always be no. I learned the hard way many years ago that you can’t neglect your transmission. What is the status of the transmission that connects Berkeley’s health research engine to the public? It is a question that all of us should ponder. by jeff reimer

Post Script Dear Friends, We have just learned that Paul Plouffe, the department’s beloved writing instructor, died suddenly Sunday morning, November 11. For 24 years Paul was the soul of our chemical engineering program, leading each and every student through ChE 185, Technical Communication for Chemical Engineers. His warm and gentle personality graced Gilman Hall, and I know I speak for us all when I say that we are in deep grief.

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A long journey to home GABOR SOMORJAI LEFT BUDAPEST TO DISCOVER A NEW LIFE AND A NEW SCIENCE Relaxing in his office, Gabor Somorjai pauses for a moment to reflect on his 43-year career at Berkeley. “A profession is a vehicle,” says Somorjai, “to achieve what you want from life. People choose a profession for three reasons — power, security or independence. Power? I wasn’t interested in that. Security? I never had any. Independence was my driving force.”

in his senior year, the Hungarian uprising began. Somorjai and his fellow students at the university were active in the revolution. But the Soviet tanks rolled into Budapest on November 4, and the crackdown began. “When the Russians began arresting people, I decided to leave the country. I was four months from getting my diploma. I hid my machine gun in my organic lab locker and headed for the border.” He took with him two companions, his sister Marietta, and, after consulting with her parents, his girlfriend (and later wife), Judith Kaldor. He was 21, she was 18.

JUDITH AND GABOR SOMORJAI

Somorjai was part of a mid-20th century Hungarian diaspora that included the scientists Leo Szilard, Edward Teller and Eugene Wigner, along with game theorist and computer pioneer John von Neuman, photographers Robert Capa and Andre Kertesz, financier George Soros, Intel co-founder and College of Chemistry alumnus Andrew Grove, and Berkeley chemical engineering professor Charles Tobias. It was Tobias who helped bring Somorjai to Berkeley as a graduate student.

Judith and Gabor Somorjai on their wedding day in Berkeley, Sept. 2, 1957. Chemical engineering professor Charles Tobias was their best man.

It was Somorjai’s fierce pursuit of independence that led him to flee Budapest after the Hungarian uprising against Soviet rule in 1956, to come to the United States to continue his education, and to turn down a lucrative promotion at IBM to return to academia to pursue his research. “Success never came easy for me,” says Somorjai. “But if you let hardship get the better of you, then you are out.” Born in Budapest in 1935, Somorjai grew up with soldiers in the streets — first Nazis, and later Soviets. He doesn’t waste time comparing the two groups. “They were both bad,” he says.

His father was a businessman, and under the Soviets, he was labeled a “class enemy.” This status at first prevented the young Somorjai from entering a university, but he played basketball and water polo, and his athletic talents earned him an exception. His father encouraged him to study chemical engineering, because he thought that his son could find employment anywhere in the world as a chemical engineer. Somorjai started at the Technical University of Budapest as a chemical engineering student in 1953. “It was the height of the Stalinist terror. People were disappearing left and right,” he says. In the fall of 1956,

“After the revolution was defeated, the engineers kept the trains moving to the west for the refugees,” Somorjai recalls. “But with solders guarding the final crossing, we had to leave the train 50 kilometers from the border. The local people hid us during the day, and we walked for four nights to the border, where guides led us to an area where we could cross safely. I remember it was late November 1956, cold and swampy.” One of Somorjai’s first recollections of the west was an Austrian Red Cross safe house, where the refugees were given food and hot drinks. Then it was on to Vienna, where he encountered fellow Hungarian émigré Cornelius Tobias, brother of Charles Tobias. Somorjai traveled to the United States with Judith, where they had been sponsored by refugee agencies. Their first home in the U.S. was Camp Kilmer, NJ.

Fall 2007 Catalyst

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The year 1957 was a good one for Somorjai. It started with a letter from Charles Tobias, letting him know that he had been accepted as a graduate student at Berkeley and had been provided with a stipend of $800. Tobias’s letter starts, “First of all, let me greet you warmly on the occasion of your arrival to this blessed country. I hope that you will be as little disappointed in your expectations as I am after 10 years of life here. Now let’s get down to business.” Other letters followed to formalize the arrangement from College of Chemistry dean Kenneth Pitzer and the Berkeley registrar.

Somorjai’s favorite class as a grad student was thermodynamics with Leo Brewer. “Brewer was an outstanding teacher with a deep knowledge of chemistry,” says Somorjai. “He made the subject come alive.” Even then Somorjai was fascinated by heterogeneous catalysis and polymers. But no one in the Department of Chemistry was working in these areas. Finally Richard Powell, a professor of inorganic chemistry, offered him a research job involving catalysis. Somorjai completed his dissertation, entited “Small Angle X-Ray Study of Metallized Catalysts,” with Powell in 1960 and joined the research staff at IBM in Yorktown Heights, NY. In 1962, while he was working for IBM, he became a U.S. citizen. It was at IBM that Somorjai’s independent streak reasserted itself. Says Somorjai, “IBM wanted me to manage a new project, but I wanted to continue to study surface chemistry.” In 1964, he decided to quit IBM and return to Berkeley as a professor, even though it meant a 50 percent salary cut. Somorjai returned to Berkeley just as the Free Speech Movement began, and as he put it, “All hell broke loose.” Powell, his dissertation advisor, was the chair of the chemistry

College of Chemistry, UC Berkeley

department (and from 1968–70 the head of the Berkeley Academic Senate), “and he, along with chemistry faculty members George Pimentel and Robert Connick, helped keep the education process undamaged on the Berkeley campus,” says Somorjai. Connick later served as the Vice Chancellor, Academic Affairs (1965-67) and as Vice Chancellor (1969-71). It was at Berkeley in 1965 that Somorjai began his path-breaking work on the chemistry of surfaces. The development of low energy electron diffraction in the 1950s and 1960s allowed researchers to study surfaces at the molecular level. Somorjai and his research group began developing vacuum systems for examining the surface properties of model catalytic materials such as platinum single crystals. Somorjai realized that the chemical properties of a surface depend upon the nature of the surface itself as much as they do on the bulk properties of the material. At the atomic level, surfaces have varied structures, and these structures induce varied chemistry. The planet Earth has large flat surfaces such as salt flats, but it also has mountains and ridges. The same is true for metal surfaces. “A smooth surface may be chemically inert,” says Somorjai, “but atoms on the surface usually restructure and move to new locations because they have fewer neighbors than atoms in the bulk and therefore are bound differently. The surface can also have steps, and kinks in the steps, and that is where the chemistry appears. If you add defects to a smooth surface, then it can

break bonds. This concept became the fingerprint of my chemistry.” Somorjai’s approach was to work with simple metal surfaces and discover how chemical reactions occur on them. He focused on platinum metal surfaces, since platinum has historically been the most important catalyst. Somorjai then moved on to more complex surfaces and nanoparticles of different shapes and sizes, similar to those used in industrial reactions. These methods have led to more efficient and more selective catalysts and have been the key driving force in the application of surfaces for advancement of microelectronics and hard disk drives, better understanding of lubrication and corrosion, and improvements in the interfaces between medical implants and the human body. More recently Somorjai’s group developed scanning tunneling microscopy methods, and working with Berkeley physics professor Ron Shen, they have developed sum frequency generation surface vibration spectroscopy to study surface reactions under real conditions without the need for placing the surface in a vacuum chamber. In addition to his colleagues and students, Somorjai credits his success, and the success of the College of Chemistry in general, to an often-overlooked asset — its machine and electronics shops. “If you look at the work of College of Chemistry Nobel laureates such as Melvin Calvin, Glenn Seaborg and Y. T. Lee, their success was based on advances in instrumentation, and we owe that to our shops,” says Somorjai.

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The diagrams to the l e f t show the varying ways molecules align themselves on the surfaces of catalysts at the atomic level. B e l o w Somorjai and graduate student Russ Renzas discuss the details of a spectroscopy experiment in Somorjai's lab at LBNL.

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a surface, and bones are porous surfaces, just like the zeolite catalysts used in the petrochemical industry. Enzymes are nanoparticle catalysts, at a scale where surface effects dominate.” Somorjai foresees that fighting global warming will require profound changes in chemistry and catalysis. He says that oil supplies are dwindling, and natural gas won’t last much longer. Coal is dirty, and cleaning it up will be a major challenge. Solar power has tremendous potential, but solar energy is often produced far from where it is needed. “We need ways to convert energy from one form to another,” says Somorjai, “and to store excess energy in chemical bonds. We will have to use energy as cleanly and efficiently as possible. In a world of carbon dioxide neutrality, we will need to rethink all of our chemical processes.”

Somorjai was named University Professor by the UC Board of Regents in 2002, the highest honor bestowed on a faculty member within the UC system. He is also a Faculty Senior Scientist in the Materials Science Division and Director of the Surface Science and Catalysis Program at the Lawrence Berkeley National Laboratory. Somorjai has won every major award that can be bestowed on a physical chemist by the American Chemical Society. In 2002, he received the National Medal of Science, the nation’s highest award for lifetime scientific achievement. Earlier this year he was awarded the Priestley Medal from the American Chemical Society, the most prestigious honor bestowed on an American chemist. He also won the Wolf Foundation Prize in Chemistry. He was elected to the National Academy of Sciences in 1979 and the American Academy of Arts and Sciences in 1983. He has seven honorary doctorate degrees from universities around the world. Somorjai has educated more than 120 Ph.D. students and almost 200 postdoctoral fellows, about 100 of whom hold faculty posi-

tions. Many more are leaders in industry. He is the author of three textbooks and over 1,000 scientific papers in the fields of surface chemistry, heterogeneous catalysis, and solid state chemistry. “Professor Somorjai could be considered the father of modern surface chemistry and to have almost single-handedly set the molecular foundations of heterogeneous catalysis,” says Francisco Zaera, a chemistry professor at UC Riverside who conducted his doctoral research with Somorjai in the early 1980s. But Somorjai is not ready to rest on his laurels. Says Somorjai, “I often ask potential assistant professors the following questions: ‘If you succeed, will you increase knowledge by an order of magnitude? If you had the best students and endless money, what would you do?’ Many people cannot answer these questions.” Somorjai would study biological surfaces, especially the brain. “The human brain is a surface, and it is folded to increase surface area without increasing head size,” he says. “Evolution loves surfaces. The skin is

That process of rethinking will be easier, thanks to Somorjai’s decades of research. “I wanted to do something important,” he says. “I put my stamp on the profession, and the profession allowed me to do everything I wanted to do in life.” Somorjai recently celebrated his 50th wedding anniversary with Judith, the 18-yearold girl who walked out of Hungary with him on a cold November day in 1956. She finished her undergraduate degree at Vassar in New York and in 1975 earned her M.S. in computer science at Berkeley. They raised two children, and photos of his four grandchildren grace his office bookshelf. They all live in the San Francisco Bay Area, as does Somorjai’s sister Marietta, who eventually came to the U.S. from Vienna and raised her family here. Says Somorjai, “Judith and I were married in the fall of 1957. I was a first-year graduate student, and for our honeymoon we took a bus to Lake Tahoe over the Labor Day weekend.” Somorjai has returned to Europe many times, including to his native Hungary. “But for my family and me,” he says, “the Bay Area is home. I look back now and see all the things I was able to do because I took the chance and came to Berkeley.” Fall 2007 Catalyst

College of Chemistry, UC Berkeley

CENTERS FOR DISEASE CONTROL

10 COURTESY DAVID SCHAFFER

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Rays of hope by michael barnes

This issue of Catalyst is the second in a series that focuses on human health. Approximately two billion people have tuberculosis. The vast majority of these cases are latent and not contagious. But estimates are that 10 percent or more of the infected, or about 200 million people, will become contagious at some point in their lives if left untreated. The havoc caused to the immune system by TB makes an infected person more likely to get, and transmit, other diseases such as AIDS and malaria. To break the cycle of transmission, new treatments are needed for TB, especially for its drug-resistant forms which have appeared in every region of the world. In the Department of Chemistry, Carolyn Bertozzi and her research group are starting with fundamentals, using the latest advances in genetics and biochemistry to build a molecular-level understanding of TB virulence and how to block it. The Bertozzi group is reaching out to collaborators — to UC Berkeley’s public health experts, to UCSF infectious disease specialists at San Francisco General Hospital, and to local biotechnology companies — to fight one of the world’s greatest killers. Meanwhile, in the Department of Chemical Engineering, David Schaffer is dealing with an emerging epidemic of a very different sort. Because we have been successful at

combating heart disease, cancer and diabetes, more Americans are living longer. When coupled with the aging of the baby boom generation, millions are reaching the age when they become increasingly susceptible to neurodegenerative diseases. About five million Americans suffer from Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). According to the NIH National Institute on Aging, about 5 percent of men and women ages 65 to 74 have Alzheimer’s disease, but nearly 50 percent of those age 85 and older may have the disease. Because of these demographic factors, in coming decades there will be an epidemic of neurodegenerative diseases — diseases for which we have no cures. Schaffer is using stem cell technologies and progenitor cells in the brain to learn to repair the neural pathways destroyed by these illnesses. Working with multidisciplinary groups of researchers at Berkeley’s Helen Wills Neuroscience Institute and the Berkeley Stem Cell Center, Schaffer is adding his unique perspective as a chemical engineer to find ways to harness the potential of stem cell therapies. The efforts of the Bertozzi and Schaffer research groups are just two examples of how College of Chemistry researchers continue to grapple with real-world problems and hunt for solutions that will improve the well-being of people all over the world.

A b o v e Cultured neural stem cells have been stained for a marker called nestin (green). These neural cells can divide indefinitely and have the potential to remedy Alzheimer's and other neurodegenerative diseases. B e l o w An electron microscope reveals the details of Mycobacterium tuberculosis. Each rod-shaped bacterium is about two microns (two thousandths of a millimeter) long.

Fall 2007 Catalyst

Unraveling The Bertozzi group confronts one of the world’s major killers

KATHEEN DURKIN

To p Carolyn Bertozzi takes a break from her responsibilities as the director of the LBNL Molecular Foundry.

B o t t o m Joseph Mougous, a former member of the Bertozzi research group, is now an assistant professor at the University of Washington. College of Chemistry, UC Berkeley

JOSEPH MOUGOUS

M i d d l e A molecule of SL-1, a virulence factor in the cell wall of TB bacteria.

n the fall of 1999, Joseph Mougous, a new graduate student in the research group of professor Carolyn Bertozzi, started looking for a research project. Mougous began by exploring the genetic sequence of the tuberculosis (TB) bacterium that had been published the previous year. In the sequence he found something unexpected, something that would eventually lead not only to his own dissertation, but also to a new research focus for the Bertozzi group — one that continues to gain momentum eight years later. Buried in the genetic code of the TB bacterium, Mougous found genes for the production of a set of enzymes that were very similar to those in humans. The enzymes helped produce sulfated glycolipids, molecules involved in cell-to-cell communication in higher animals. What were these genes doing in a bacterium, he wondered? Were they an integral part of the microbe’s genome, or were they evolutionary baggage, bits of junk DNA? Did they help produce the unique characteristics of TB that make it so dangerous and difficult to treat? The researchers who first published the TB genome in Nature magazine (11 June 1998) had noted many unusual aspects of the bacterium. “Novel biosynthetic pathways generate cell-wall components and several of these may contribute to mycobacterial longevity,” the researchers wrote. “…TB contains an additional layer that is exceptionally rich in unusual lipids, glycolipids and polysaccharides.” Starting from these genetic clues, Mougous and the Bertozzi group began their search to understand the TB bacterium and to find new ways to disrupt its lifecycle. The terms “glyco” and “saccharide” are hints that these complex organic molecules are built from simpler sugars. For Bertozzi, understanding the chemistry of these sugarbased molecules, and the role they play in disease and health, including cancer and inflammatory disease, has become her life’s work. Bertozzi is the T. Z. and Irmgard Chu Distinguished Professor of Chemistry and professor of molecular and cell biology at Berkeley. She obtained her undergraduate degree from Harvard University in 1988 and her Ph.D. from Berkeley in 1993, both in chemistry. After a postdoctoral appointment at UCSF, she returned to Berkeley as a faculty member in 1996. She is also an Investigator of the Howard Hughes Medical Institute, a faculty affiliate at QB3, and

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TB’s deadly mysteries the director of the Molecular Foundry, a nanoscience institute at the Lawrence Berkeley National Laboratory. She has won numerous awards, including several campus teaching awards and a MacArthur Foundation “genius” award. The inventor Thomas Edison once remarked, “Genius is 1 percent inspiration and 99 percent perspiration.” Edison would have appreciated Bertozzi’s work ethic. She is a perpetual motion machine, some weeks spending almost as much time in the air flying to and from meetings as she does on the ground. Yet she still holds together a research group of almost 50 people, including undergraduates. The Bertozzi group’s progress in unraveling the metabolic mysteries of the TB bacterium has been due to painstaking research over the course of several years. “Back in 1999,” says Bertozzi, “we knew that sulfated glycans, or sugar-based molecules that contain sulfur, play important roles in cell-to-cell communication in higher animals. But we didn’t know much about the functions of these sulfated glycans in bacteria in general, much less in TB specifically.” TB is a uniquely human disease, and the organism that produces it has been co-evolving with humans for thousands of years. The TB bacterium may have adapted to its host by mimicking human cell-to-cell signaling pathways. “If we could learn how TB manipulates the immune system,” says Bertozzi, “we might be able to identify new anti-TB drug candidates.” Prior to the Bertozzi group’s work, only one TB sulfated glycolipid was known — sulfolipid-1 (SL-1). Its biosynthetic machinery had remained a mystery for over 40 years. After the group unraveled many of the SL-1 biosynthetic pathways, Bertozzi, Mougous, and collaborators in Berkeley’s molecular and cell biology and public health departments began to look for ways to block the production of SL-1 and other sulfated molecules. The sugar trehalose seemed like a good place to begin. It is one of the fundamental building blocks of TB glycolipids like SL-1. Starting from trehalose, the TB bacterium synthesizes SL-1 by adding long lipid chains and a sulfate (SO42-) group. Trehalose is a disaccharide, composed of two glucose molecules. In appearance, it is not that different from sucrose, the sugar we sprinkle on our cereal and put in our coffee. Sucrose is also a disaccharide, but it is composed of one molecule of glucose and one of fructose.

“Most bacteria, plants, and insects synthesize trehalose,” says Bertozzi, “but higher order vertebrates, like humans, don’t. We thought that if we found a drug candidate that interfered with trehalose biosynthesis, it could reduce the virulence of TB without having much of an effect on the person with TB who was taking it.” Bertozzi’s original hunch was correct — too correct. Trehalose is so important to the TB bacterium that it has evolved three redundant pathways to produce the sugar. Finding a drug that would block all three pathways of the trehalose biosynthesis system would be a very complex task. So Bertozzi set aside trehalose as a target and kept looking for other ways to block the production of sulfated glycolipids. Bertozzi and colleagues have had more success by targeting another way the TB bacterium uses sulfur-containing metabolites for its self-defense. TB bacteria can survive for decades in a dormant state inside macrophages, our immune system’s killer cells. Once they engulf bacteria, macrophages launch a barrage of potent oxidants, including nitric oxide, to kill the invaders. Says Bertozzi, “We know sulfur-containing metabolites help protect other organisms against oxidants, and we speculated that the enzymes involved in sulfur assimilation might be vital for survival of TB during its latent phase inside macrophages.” CysH is an enzyme essential for the TB bacterium to produce sulfur-containing metabolites. Bertozzi had discovered that disruption of CysH synthesis renders the TB bacterium incapable of producing cysteine and methionine, two sulfur-containing amino acids, as well as a cofactor called mycothiol that the bacteria use to protect themselves from oxidants. Disruption of CysH, Bertozzi found, also reduces the virulence of TB in mice. “CysH helps protect the TB bacterium,” say Bertozzi, “so that makes it an interesting target. In the last several years, working with Professor Lee Riley’s group in public health, we’ve been able to produce a genetically altered ‘knock-out’ strain of TB that lacks the CysH altogether, and we’ve found that this weakened version has potential as a vaccine, at least in the mouse model of TB.” The current vaccine for TB, the Bacillus Calmette-Guérin (BCG) vaccine, was developed in the 1930s in Europe. It is based on an attenuated strain of Mycobacterium bovis, the relative of the TB pathogen that usually infects cattle. The BCG vaccine is used mostly

Fall 2007 Catalyst

The role of glycans in understanding health and disease continues to make news in scientific circles. Recent articles in the scientific literature discuss the role of complex sugar-based molecules in HIV (Science, 28 Sept 2007), malaria (Chemical & Engineering News, 17 Sept 2007) and even bone growth (ACS Chemistry of Materials, 16 Oct 2007). Research on glycans is blossoming — due in part to Bertozzi, her collaborators and the students they have trained. Bertozzi is pleased but not surprised. “I’ve been fortunate to have worked with great students and colleagues over the years, and to have gotten support from visionary public and private funding sources. TB is a terrible disease. With more hard work and a little luck, in the next several years we’ll make significant progress in the fight against it.”

COURTESY OF MICHAEL SCHELLE

to vaccinate children in developing countries where TB is endemic. It has a number of drawbacks, including the waning of protective immunity over time, variable effectiveness in adults, and a poor safety record in immunocompromised individuals. “It’s hard to believe that the only vaccine currently being used against TB was developed 70 years ago,” says Bertozzi. “There is a desperate need for a better TB vaccine, and we’re hoping our work will help start the process of developing a new one.” The potential of the Bertozzi group’s research recently caught the eye of a local biotech company, Gilead Sciences, of Foster City, CA. Gilead specializes in products to treat infectious diseases such as HIV and hepatitis. Its $499,500 gift will boost Bertozzi’s research. “The Gilead funds will allow us to hire a staff scientist who will provide the continuity necessary for an extended research project,” says Bertozzi. “It’s wonderful that a local biopharmaceutical company has the foresight to invest in this type of academic research.” Michael Schelle (Ph.D. ’07, Chem), a recent graduate of the Bertozzi group, has been appointed the staff scientist in charge of a new TB lab. Schelle is looking forward to extending the group’s work by examining lung samples from TB patients. “Up to now, we have pretty much been confined to working with mouse and other animal tissues to study TB,” says Schelle. “The problem is that the animal models may not be that helpful. TB is a human disease — in the wild, mice don’t get TB.” Although many drugs against TB are losing their effectiveness, Schelle explains that they are effective enough that the older invasive surgical procedures — removing a lung or cutting away diseased lung tissue — are almost never performed. That makes samples of TB-infected human tissues very difficult to find. Through collaboration with San Francisco General Hospital, the Bertozzi group is hoping to work with biopsy samples from TB patients. Says Bertozzi, “In addition to providing indigent care, S.F. General is staffed by UCSF doctors who do amazing research on trauma, AIDS, TB, and other illnesses. We are looking forward to working with Phillip Hopewell, who is one of the best TB doctors in the country.” Bertozzi has been able to keep Schelle as a staff scientist. But what became of Joseph Mougous, the grad student who first interested the group in TB eight years ago? He is now back in his native Pacific Northwest as an assistant professor at the University of Washington, where he continues to study cell-to-cell interactions between microbes and their hosts. As a user of the Molecular Foundry at LBNL, he keeps in touch with Bertozzi. Says Mougous, who earned his Ph.D. in molecular and cell biology in 2004, “The Bertozzi lab was where I learned to love microbiology and host-pathogen interactions. It was a great environment to learn in, one that really allowed me to explore interesting scientific questions without a lot of barriers.”

T B l i f e c y c l e : TB bacterium is engulfed by macrophage (1), but survives by entering dormant phase (2). Macrophage recruits other immune system cells called leukocytes (3) to help counter infection, forming granuloma (4). Latent TB can survive for decades inside granuloma (5). For reasons not yet understood, TB can become active, releasing new bacterium from granuloma and starting active infection (6). B e l o w : Bertozzi entertains her research group over pizza at an evening group meeting. Michael Schelle (center background), is a recent Ph.D. graduate from the group and will head the new TB lab.

College of Chemistry, UC Berkeley

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What is tuberculosis? • Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can attack any part of the body, including the kidney, spine, and brain. • TB is spread through the air from one person to another. The bacteria are put into the air when a person with active TB of the lungs or throat coughs or sneezes. People nearby may breathe in these bacteria and become infected. • Not everyone infected with TB bacteria becomes sick. People who have latent TB infection do not feel sick, do not have any symptoms, and cannot spread TB to others. However, some people with latent TB infection eventually develop active TB. • One-third of the world’s population is infected with TB, although most cases are latent. • Approximately 10 percent of the infected population will develop active TB in their lifetimes if left untreated. • If not treated properly, TB can be fatal. Once the leading cause of death in the United States, TB still killed 1.6 million people worldwide in 2005. • People with active TB can be treated if they seek medical help. Even better, most people with latent TB infection can take medicine so that they will not develop active TB.

Drug-resistant TB • Starting in the 1940s, scientists discovered the first of several medicines now used to treat TB. As a result, TB slowly began to decrease in the United States. But TB is still a problem; more than 14,000 cases were reported in 2005 in the United States. • BCG is a vaccine for TB. This vaccine is not widely used in the United States, but is often given to infants and small children in other countries where TB is common. BCG does not always protect people from getting TB. • MDR-TB (multidrug-resistant tuberculosis) is a form of TB that does not respond to the standard treatments and is defined as TB-resistant to the main first-line drugs. There are an estimated 424,000 new cases of MDR-TB worldwide every year. The cost of treating MDR-TB can be 1,000 times more than the cost of treating standard TB. • XDR-TB (extensively drug-resistant TB) occurs when there is resistance to all of the most effective anti-TB drugs, and is defined as TB with MDR-TB resistance as well as resistance to many of the second-line drugs. • There are an estimated 25,000 to 30,000 new cases of XDR-TB every year. So far, 37 countries have confirmed cases of XDR-TB. In the United States, 49 cases of XDR-TB were reported between 1993 and 2006. • World Health Organization guidelines stipulate that people with infectious TB must postpone longdistance travel, while those with MDR-TB must postpone any air travel.

sources: world health organization and centers for disease control and prevention

Fall 2007 Catalyst

Renewing David Schaffer is using stem cells to blunt the coming epidemic of neurodegenerative disease

A b o v e Schaffer in his new lab in Stanley Hall, where his group works with researchers from several different fields to develop stem cell technologies to help fight neurodegenerative diseases. B e l o w The human brain contains neural stem cells that create new neurons every day. These cells have the potential to differentiate into the major cell types of the nervous system: neurons (not shown), astrocytes (red) and oligodendrocytes (green).

College of Chemistry, UC Berkeley

he wonderful thing about stem cells is that they can develop into almost any type of cell that you could want. The problem with stem cells is that if their growth is not well controlled, they will develop into types of cells you don’t want. This is the conundrum facing chemical engineering professor David Schaffer. He works on engineering brain cells called neurons to replace those that have been damaged or destroyed by illnesses such as Alzheimer’s disease, Parkinson’s disease, or amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease). Says Schaffer, “Stem cells are immature cells that exist in various locations in our bodies. During our lives, these cells divide and develop into specialized tissues. If we get a disease that kills those specialized tissues, our stem cells have the potential to replace the lost cells. “But,” he continues, “in order to engineer the right type of new tissue, we have to learn to control stem cells by learning how the body’s signals regulate their growth and differentiation. That’s the hard part.” At first, it may seem odd that a chemical engineer is working with stem cells. But for Schaffer, it is a logical development of the rise of new industries such as microelectronics and biotechnology, and a reflection of the new roles chemical engineers play in them. Chemical engineers have always been vital to the pharmaceutical industry, where they manage the production of drugs in large chemical reactors. With the founding of Genentech, Chiron and other biotech companies, human insulin and human growth hormone began to be produced in genetically modified yeast and bacterial cells. Chemical engineers, who for decades had worked with microorganisms in the process of fermentation, brought their expertise to the production of these new drugs. “Working with stem cells takes this process one step further,” says Schaffer. “We can now genetically engineer single-celled bioreactors to produce useful drugs. But we still have to get the medications back inside the body. In many cases, it would be better if we could put the cells inside the body and let them produce their drugs there.” Schaffer cites the treatment of diabetes as an example. During the early 20th century, researchers learned to treat diabetes with insulin derived from the pancreases of slaughtered pigs. With the advent of biotechnology in the 1980s, drug companies began to produce human insulin. However, that insulin still has to be injected back into the human body.

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the brain “With stem cell therapies,” says Schaffer, “we have the potential to create new insulin-producing cells to replace the damaged cells inside the human pancreas. This is the ideal place for them because the body possesses regulatory mechanisms to check blood sugar levels and make sure that insulin is produced in the right amounts. Ironically, as our technologies have gotten better, we have been using them to more closely mimic the original solutions of nature.” Diseases of the brain are tougher. There are no medications that can cure Parkinson’s, Alzheimer’s, or ALS. “Millions of Americans suffer from neurodegenerative diseases,” says Schaffer, “and most of them have Alzheimer’s. These diseases tend to strike people in their 50s and 60s. With the aging of the baby boomers, we are at the beginning of an epidemic of neurodegenerative diseases — an epidemic that we have no cures for.” Although Schaffer approaches health issues from a chemical engineering perspective, his original exposure to them came from growing up in a medical family. Schaffer’s parents met in graduate school at the University of Minnesota in Minneapolis. His father, from Minnesota, was working on a Ph.D. in biochemistry. His mother was trained as an M.D. in El Salvador, came to the United States to study biochemistry, and went on to run clinical trials at Novartis. Schaffer’s sister is also a physician. Schaffer graduated from Stanford University in 1993 and earned his Ph.D. in chemical engineering from MIT in 1998. While at MIT he worked with professor Doug Lauffenburger on gene transfer, and he also studied molecular and cell biology. Schaffer then began a postdoctoral fellowship in the laboratory of Fred Gage at the Salk Institute for Biological Studies in La Jolla, CA, studying the role of neural stem cells in plasticity and adaptability of the adult central nervous system. Schaffer joined UC Berkeley’s chemical engineering department as an assistant professor in 1999. “The Gage lab at Salk was and is an incredible place to be,” says Schaffer. “In the late ’90s, Gage was showing — contrary to the existing neuroscience dogma — that animals, including humans, do grow new brain cells after birth. The Gage lab also showed that mice raised in cages with lots of stimulation grew more new brain cells than mice housed in standard laboratory cages, and that exercise stimulates new brain cell growth.” At Berkeley, Schaffer is combining his Ph.D. and postdoc experience by using the gene transfer techniques he first studied at MIT to regulate the development of neural stem cells that he

learned about at Salk. Says Schaffer, “A major research thrust of my lab is exploring the therapeutic potential of gene delivery, which serves as an effective means to control stem cells. Viruses are nature’s professional gene carriers, and we are working with several different viruses to perfect the transfer of genetic information to neural stem cells.” Schaffer and his colleagues are helping overcome one impediment to gene therapy—the human immune response. The immune system is an amazingly complex and effective system for protecting our bodies against bacteria, viruses, and the illnesses they cause. Yet in some cases, the immune response can get in the way of treating disease. Schaffer has devised a technique to circumvent the immune response to potential gene therapy vectors such as the adeno-associated virus (AAV), a common, though innocuous, resident of the body. Schaffer has created new versions of AAV that are good candidates for gene therapy vectors, particularly for delivery to stem cells. In addition to the genetic and biological issues in working with neural stem cells, there is a physical problem—the stem cells need to stay put. They cannot regenerate the correct issues if they are floating around at random inside the brain. In a soon-to-be-published paper, Schaffer and co-authors describe a clever solution in the form of a scaffold, a three-dimensional equivalent to the dissolvable stitches that are used in surgery. Schaffer has fabricated a hydrogel scaffold from a material called alginate, which occurs naturally in brown seaweed, and which is highly compatible with human nervous system tissue. Hydrogels are soft, flexible materials, such as contact lenses, that contain mostly water. The alginate scaffolding is used to encapsulate the neural stem cells and anchor them in the proper location in the brain. Just as dissolvable stitches slowly disappear once they have done their job of holding tissue together, the alginate hydrogels slowly dissolve once the neural stem cells have implanted and have begun to function. One issue is that the hydrogels on their own don’t dissolve fast enough. Schaffer and colleagues solved this problem by embedding microcapsules of enzymes in the scaffold, enzymes that cause the hydrogel to disintegrate. “By controlling the amount of enzyme and its rate of release from the microspheres,” says Schaffer, “we can control how fast the hydrogel scaffold degrades. Another possibility we are considering is adding chemical growth factors to the microspheres that will help regulate the stem cell development.” Fall 2007 Catalyst

Schaffer’s multidisciplinary approach to his stem cell and gene therapy research permits him to wear many hats and to interact with a wide range of researchers. He has been affiliated with Berkeley’s Helen Wills Neuroscience Institute since he arrived on campus. The institute integrates neuroscience faculty across the university, with the broad goal of using the power of diverse research approaches to address central questions in neuroscience. Schaffer is also the associate director of the Berkeley Stem Cell Center, a multidisciplinary group of biologists, physical scientists, and humanities and legal scholars committed to the study of this new technology. The Stem Cell Center coordinates world-class research in cell and developmental biology, chemistry, bioengineering and chemical engineering on campus. Research activities are supported by grants from the California Institute for Regenerative Medicine, NIH, private foundations, and private philanthropic donations. Along with colleagues Sanjay Kumar (bioengineering) and Kevin Healy (biomaterials engineering), Schaffer has been awarded a $70,000 grant from the Chancellor’s Faculty Partnership Fund to enhance stem cell research. A researcher at LBNL, Schaffer is also affiliated with QB3, and his lab is located in Stanley Hall. In the United States, progress in stem cell research has been slowed by restrictions in federal funding. Although federal research funding is allowed for some existing stem cell lines, many of these cell lines have questionable properties or have become contaminated with material from animal cells, which would cause them to be rejected by the human immune system. In California, the voter-approved initiative, Proposition 71, authorized the allocation of $3 billion to support stem cell research and the development of stem cell-based therapies through the California Institute for Regenerative Medicine (CIRM). CIRM has been embroiled in legal battles since its inception, but the research money has begun to flow. Schaffer and Berkeley recently won a $2.1 million grant from CIRM to expand the research program at the Berkeley Stem Cell Center. Not all stem cell therapies are controversial, Schaffer points out. “The bone marrow transplants that routinely save the lives of children with leukemia rely on stem cells in the bone marrow to regenerate the immune system,” says Schaffer. “This therapy has been available for decades and has saved thousands of lives. “It’s been almost 20 years since the first baby was born in 1978 by in vitro fertilization (IVF),” Schaffer adds. “Hundreds of thousands of babies have been born by IVF in the United States alone since then. One consequence is that there are several hundred thousand frozen embryos that were created for IVF but were never used and will eventually be discarded. These could be used by stem cell researchers to save lives.” Schaffer cautions that new stem cell therapies are still many years away. “We are still in the research phase,” he says “We are still learning how stem cells grow and differentiate, and how to control that growth. It may be a decade or two before we understand stem cells well enough to create routine medical interventions for diseases like Alzheimer’s, Parkinson’s, and ALS. The potential is tremendous, but so is the work we still have to do.” College of Chemistry, UC Berkeley

A b o v e Schaffer is studying viruses to better understand how they insert genetic information into bacteria and animal cells. Genetic information carried by viruses may be used to control stem cell differentiation. B e l o w The hippocampus is one of the two regions of the adult brain where stem cells actively divide and create new neurons. The tissue is stained for several markers: NeuN (green) marks mature neurons, GFAP (red) marks astrocytes, and BrdU (blue) marks the stem cells. Over the course of several weeks, a fraction of these stem cells will stop dividing and turn into new neurons.

“In order to engineer the right type of new tissue, we have to learn to control stem cells by learning how the body’s signals regulate their growth and differentiation.”

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Medal of Science is the nation’s highest scientific honor, given for outstanding contributions to knowledge in the physical, biological, mathematical, engineering, social and behavioral sciences. Hoffman herself won the medal in 1997 for her work in nuclear chemistry. Other College of Chemistry faculty members who have received the National Medal of Science are Melvin Calvin, Harold Johnston, Y. T. Lee, George Pimentel, Kenneth Pitzer, Glenn Seaborg, and Gabor Somorjai.

Michelle Chang wins New Faculty Award Michelle Chang, the chemistry department’s newest assistant professor, has won a Camille and Henry Dreyfus Foundation New Faculty Award. Designed to help initiate an independent research program, the award provides a new professor with an unrestricted research grant of $50,000. Chang comes to the department from the lab of chemical engineering professor Jay Keasling, where she was a postdoc from 2004-07. Chang co-authored several of the group’s papers on using engineered bacteria to produce a class of compounds that includes the anti-malaria drug artemisinin and anticancer drug taxol. Chang’s interest in pharmaceuticals embraces organofluorine chemistry, the source of many important drugs, including Prozac, Lipitor, and Cipro. Chang will be part of the Berkeley/LBNL Energy Biosciences Institute, where she will help develop bacteria to convert biomass to fuels. Recent winners of the award in the chemistry department include Matt Francis (2001), Dean Toste (2002), and Chris Chang (2004).

Iglesia receives Humboldt Award to conduct research in Germany Chemical engineering professor Enrique Iglesia has received a 2007 Humboldt Research Award from Germany’s Alexander von Humboldt Foundation. The foundation was established by the Federal Republic of Germany in 1953 for the promotion of international research collaboration. Humboldt Award winners — scientists and scholars whose fundamental discoveries, new theories, or insights have had a significant impact on their own discipline and who are expected to continue producing cuttingedge achievements — are invited to spend up to a year working with colleagues at research institutions in Germany. Iglesia,

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Hoffman was also recently honored with the John V. Atanasoff Discovery Award, presented by her alma mater, Iowa State University, and given to an alumnus/a of Iowa State who has furthered scientific knowledge of the nation and the world. Enrique Iglesia

whose research focuses on heterogeneous catalysis and chemical reaction engineering, will divide his time between the Max-PlanckGesellschaft in Berlin (with Professor H. J. Freund) and the Technischen Universität München in Munich (with Professor J. Lercher). Iglesia will also receive a Doctor Honoris Causa from the Universidad Politecnica de Valencia, Spain, in November.

The Atanasoff award is named after John Atanasoff, the inventor, along with graduate student Clifford Berry, of the world’s first electronic digital computer, built during 1937 to 1942. The computer incorporated several major innovations in computing, including the use of binary arithmetic, regenerative memory, parallel processing, and separation of memory and computing functions.

Hoffman named to President’s Committee on the National Medal of Science Chemistry professor Darleane Hoffman has been named to the President’s Committee on the National Medal of Science. This committee of 12 scientists and engineers is appointed by the president of the United States to evaluate the nominees for the National Medal of Science. The National

Darleane Hoffman

Fall 2007 Catalyst

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The Merck Chair in Biochemical Engineering

talented graduates for the biotech, pharmaceutical and environmental industries. This excellence did not escape the attention of Merck & Co. and the Merck Company Foundation, which have been supporting the program for more than 25 years. Now Merck has taken the next step and established The Merck Chair in Biochemical Engineering.

L e f t t o R i g h t Chemical engineering’s Jeff Reimer and Harvey Blanch met with Merck’s Philip Woodrow and Barry Garfinkle to discuss the new Merck chair, awarded to Blanch this fall.

Berkeley’s program in biochemical engineering grew up with — and indeed helped to pioneer — the biotech industry and the revolution in molecular biology on which it was based. As early as the 1960s, when most departments of chemical engineering were focused on educating students to go into the petrochemical and chemical industries, professor Charles Wilke began exploring the kinetics of microbial growth and gas-liquid mass transfer in biochemical engineering. The program grew with the addition of professors Harvey Blanch in 1978, Douglas Clark in 1986, Jay Keasling in 1992, David Schaffer in 1997, and most recently Jhih-Wei Chu in 2006. The biochemical engineering program continues to be one of the largest in the country — producing

College of Chemistry, UC Berkeley

One of the advocates for establishing the chair was John Markels (Ph.D. ’94, ChemE, with Professors Clayton Radke and Scott Lynn), a member of the college’s advisory board. Currently Vice President for EMEA Operations and in charge of Merck’s manufacturing in Europe, the Middle East and Africa, John had been working at Merck when he had an opportunity to come to Berkeley for his doctorate—at the company’s expense. He became acquainted with the faculty in the biochemical engineering program, and when he returned to Merck, he and his colleagues continued recruiting Berkeley’s students in the field. In discussing the chair, Markels wrote, “Both the technical leaders in Merck Manufacturing Division (Science and Technology) and in Merck Research Labs (Early Development) who are responsible for the bio area see this as an important opportunity both for UCB and for Merck going forward — as you know we also have a heavy interest today in vaccines and a rapidly growing interest in therapeutic proteins and monoclonal antibodies, so our futures are linked.” “Merck has a strong historical relationship with UC Berkeley which has been based on strong faculty relationships and new

talent that has come to Merck,” said Philip Woodrow, Executive Director for Science and Technology Development in the Merck Manufacturing Division. “As we face the challenges to explore, understand and apply learnings on the frontiers of chemical and biological engineering research, we look to UC Berkeley as an institution for continuing and furthering our support. “We felt that establishing a Merck Chair in Biochemical Engineering will support the teaching, research and scholarship of a distinguished senior faculty member in the field of Biochemical Engineering in the Department of Chemical Engineering, College of Chemistry, at the University of California, Berkeley,” said Woodrow. The Merck Chair has been awarded to Harvey Blanch, who was honored on the occasion of his 60th birthday by his graduate students and colleagues in the field at a special symposium at the 2006 AIChE conference. A large number of his students are employed at Merck. “We are pleased that the school and Regents of the University of California have agreed to this initiative and have named Professor Harvey Blanch as the Merck Chair,” said Woodrow. Added Markels, “I am absolutely thrilled to reinforce Merck’s commitment to biotech research and Berkeley through the Blanch chair, and I look forward to watching the fruits of Harvey’s team’s work develop as this goes forward.” by jane scheiber

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The Theodore Vermeulen Chair in Chemical Engineering It was just 60 years ago that dean Wendell Latimer recruited a young researcher from the Shell Development Company in San Francisco to develop a new chemical engineering program in the College of Chemistry. For the next 36 years, Theodore Vermeulen gave unstintingly of his time and effort to build the chemical engineering department, to be of service to the university, and most of all to support his colleagues and to mentor his students. And now those colleagues and students have shown the same generosity of spirit by joining Ted’s family in establishing The Theodore Vermeulen Chair in Chemical Engineering.

Mary Dee Vermeulen celebrates with ( l e f t t o r i g h t ) chemical engineering’s Jud King, chair Jeff Reimer, former Vermeulen student Joon Moon and Alex Bell. Bell has been named the first holder of the Vermeulen Chair.

Born in Los Angeles in 1916, Ted Vermeulen received his B.S. and M.S. from Caltech. In 1942 he earned the first chemistry doctorate ever awarded by UCLA, and he then worked at Shell until 1947. At Berkeley, Ted inherited a fledgling chemical engineering curriculum that had been introduced in the College of Chemistry in 1946 under the direction of professor Phillip Schutz, who passed away shortly thereafter. To the initial faculty of LeRoy Bromley and Charles Wilke, Ted soon added

Don Hanson, Charles Tobias, and F. C. Williams. Under Ted’s guidance, the curriculum was quickly accredited, and a Division of Chemical Engineering was created in 1951, with Ted as the first chairman. It was one of the first such substantial university programs of its kind. In 1953, following the customary rotation of the chairmanship, Ted left his formal administrative role in the department, but not his service. He was instrumental in establishing the options program and joint degrees with Materials Science and Nuclear Engineering. He taught most of the undergraduate courses in the curriculum, and in 1980 he became the director of the Sea Water Conversion Laboratory (later the Water Thermal and Technology Center). Outside of the college, Ted served on nearly all of the major committees of the Academic Senate, taking particular pride in his work on the Muscatine Select Committee on Education during the period of student unrest in the mid-1960s.

Engineers, among other honors. But it was his exceptional helpfulness as a human being for which many of his students and colleagues most remembered him. Ted lost a brief and valiant struggle against leukemia in 1983, but not before he had laid the foundations for the future growth and excellence of the department — a wonderful legacy to the university. At the time of his passing, a number of his former students and colleagues wished to create an additional legacy and established a special fund in his memory. His widow, Mary Dee Vermeulen, and her family added to the fund annually. Over the years, the income from that fund was used to recognize outstanding undergraduates in chemical engineering with the Theodore Vermeulen Award and to provide summer research stipends. In 2005, Mary Dee Vermeulen made a very generous gift to the memorial fund with the goal of establishing The Theodore Vermeulen Chair in Chemical Engineering. Rallied by Professor Emeritus C. Judson King and former students Michael Kavanaugh (M.S. ’64, ChemE) and Joon Moon (Ph.D. ’64, ChemE), who also provided a generous

“Being an engineer, I like to think in terms of maximizing return and yield. Contributing to the Vermeulen Fund does both efficiently; it directly funds a person who will teach and influence our future generations, and it gives satisfaction to the donor by reminding him of his own good fortune in getting such a good UC education with the help of outstanding faculty such as Professor Vermeulen.” –Joon Moon, Ph.D. ’64, ChemE

All the while, he maintained a vigorous research and teaching program, authoring more than 90 publications and directing 97 graduate students. His work, especially in ion exchange, absorption, and other fixed bed operations, was widely recognized and earned him the William H. Walker Award of the American Institute of Chemical

challenge grant, Ted’s former students and colleagues contributed the remaining funds to fully endow the chair. Professor Alexis T. Bell, who was chairman of the department when Ted passed away, has been named the first holder of the Theodore Vermeulen Chair. by jane scheiber Fall 2007 Catalyst

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Dow gives $2 million for sustainable products With an initial $2 million gift announced, the University of California, Berkeley, will establish a new program aimed at providing students educational and research opportunities in the area of sustainable products and solutions. Based at the Center for Responsible Business at the Haas School of Business, the Sustainable Products and Solutions (SPS) Program is being established in partnership with the College of Chemistry. It is being financed initially with $2 million in seed money from the Dow Chemical Co. Foundation. The foundation intends to provide a total of $10 million over the next five years and to help the program secure additional foundation and corporate sponsors. The program was the idea of Dow vice president David Kepler (B.S. ’75, ChemE).

The program will focus on sustainability issues involving society, science, engineering, the environment and finance. A request for proposals will be issued later this fall seeking research and education ideas, primarily from master’s degree-level and doctoral students at UC Berkeley. News related to the Sustainable Products and Solutions Program will be posted at http://www.haas.berkeley.edu/responsible business/.

JBEI: Alternative energy research thrives at Berkeley The Department of Energy has awarded a $125 million, five-year grant to Lawrence Berkeley National Laboratory (LBNL), UC Berkeley, and four other partners to develop better biofuels in a new center to be known as the Joint BioEnergy Institute (JBEI). The establishment of JBEI, concurrent with the founding of the new Energy Biosciences Institute (see Chair Marletta’s column on page 4), affirms the position of Berkeley and the Bay Area as the nation’s center of alternative energy research. JBEI draws on a wellspring of talent in the Department of Chemical Engineering. Its chief executive officer is Jay Keasling, the Hubbard Howe Jr. Distinguished Professor of Biochemical Engineering. Harvey Blanch, the Merck Professor of Biochemical Engineering, is its chief science and technology officer. Research at JBEI will center on improvements to current technology for producing ethanol, in particular cellulosic technology for producing ethanol from biomass, and new technologies for producing other biofuels. The additional partners in JBEI are Sandia National Laboratories, Lawrence Livermore National Laboratory, UC Davis, and Stanford University. JBEI will be headquartered in Emeryville in the East Bay, central to all partners. Initial work is taking place at the West Berkeley Biocenter.

Hewlett Foundation gives unprecedented $113 million for endowed chairs The William and Flora Hewlett Foundation has bestowed on Berkeley the largest private gift in the campus’s history — $113 million. The extraordinary gift provides Berkeley with a key source of funding to attract and support superior faculty and graduate students. Through a challenge grant, it will create 100 endowed chairs — permanent funds designed both to keep Berkeley professors’ salaries competitive with those at the best private schools and to recruit top graduate students. The challenge grant will match other private donations dollarfor-dollar, resulting in $220 million in new endowments once the challenge is met. An additional $3 million will be used to support an enhanced infrastructure for managing those endowed funds.

The Hewlett gift represents a turning point in the financing of public higher education, providing endowment support to help narrow the funding gap between the nation’s preeminent public university and its private peers. Each year, an increasing number of Berkeley professors receive lucrative offers from elite private schools. The new endowed chairs will be valuable aids in retaining sought-after faculty members and in maintaining the high quality of a Berkeley education. “Berkeley is the crown jewel of public higher education — not just in California, but in the country,” said Walter Hewlett, chairman of the board of the Hewlett Foundation. “The foundation's grant represents our vote of confidence in a truly great institution.”

$113,000,000

Chemical engineering professor Doug Clark is the steering committee faculty co-chair for the Sustainable Products and Solutions Program.

College of Chemistry, UC Berkeley

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amazing talent of Cal alumni. Our alumni are a valuable resource, and we are thankful that these panelists offered their time and involvement. REBECCA ZUCKERMAN Ph.D. 2000, Chem

Dear fellow alumni, I would like to take this opportunity to thank Dean Charles Harris for his continued support of the Alumni Association. He has done a great job offering insightful suggestions to the steering committee and fostering enthusiasm. We really appreciate his involvement in the events sponsored by the Alumni Association, and we wish him the best as he returns to his full-time responsibilities as professor. I would also like to acknowledge my fellow steering committee members: G.V. Basbas, Bud Blue, Gordon Chu, Laurie (O’Connor) Dockter, Marissa Drouillard, Mark Ellsworth, Lara Gundel, Deanne Krenz, Larry Perry, Daisy Quan, Steve Sciamanna, and Lindy Vejar. We have had several activities in the recent past that I would like to share. On Cal Day in April, chemistry lecturer Michelle Douskey and Lonnie Martin presented “Molecules, Materials & Us” in Pimentel Hall. Following their “explosive” demonstrations, there was a campus-sponsored panel discussion, titled “Curbing Climate Change: Energy Initiatives that can Make a Difference.” Professors Jamie Doudna Cate (chemistry), Alex Farrell, Dan Kammen, and Chris Somerville were the speakers. Our third annual Springfest was held at the Pyramid Alehouse last May with more than 60 graduating students and alumni in attendance. This was a great opportunity to celebrate and offer congratulations to the graduating students for their milestone achievement. It was very festive, and Dean Harris expressed his pride in the students and the educational program that Cal provides. I encouraged the new graduates to

stay in touch and become involved with the college. We held our first “Fast Forward to Your Future” in September. Aimed at assisting our current students — both undergrads and graduate students — with career planning, this program drew on the expertise and involvement of many of our alumni. The evening began with a résumé review by counselors from the career center, followed by an inspirational speech by Dean Harris. In an effort to encompass the interests of all of our students in the College, three career-oriented alumni panel discussions were held. The Chemistry panelists included Laurie Dockter (B.A. ’71, Chem), Chabot Junior College; Mark Ellsworth (Ph.D. ’93, Chem), Tyco Electronics; Lara Gundel (Ph.D. ’75, Chem), LBNL; Kim Thomas (Ph.D. ’78, Chem), LANL; and Alex Trimble (Ph.D. ’02, Chem), Townsend and Townsend and CREW LLP. The Chemical Biology/Biotech panelists were David Gee (B.S. ’76, Chem), Kaiser Permanente; Lindy Vejar (B.S. ’85, Chem), Bio-Rad Laboratories; and myself, Rebecca Zuckerman (Ph.D. ’00, Chem), Plexxikon. The Chemical Engineering panelists were Erin Mayfield (B.S. ’04, ChemE), Chevron; Curt Munson (Ph.D. ’85, ChemE), Chevron; Larry Perry (B.S. ’56, ChemE), California Health State Dept.; Alyssa Roche (B.S. ’87, ChemE), Chevron; and Steve Sciamanna (B.S.’78; Ph.D. ’85, ChemE), Chevron. It was great to be able to share so much expertise and diversity with the college’s students. At the sushi reception that followed, many students commented on the

Most recently we celebrated Homecoming on Saturday, October 13. Our morning program was co-hosted with the College of Engineering and included a complimentary continental breakfast in the Stanley Hall Atrium, followed by a panel discussion titled “In Service to Society: Energy and Health” with professors Jay Keasling (chemical engineering) and Dan Kammen (nuclear engineering). The presentations were outstanding; those who were unable to attend can check out our home page at chemistry.berkeley.edu for the taped video of the presentations. Our “Free Radicals” and “CHEMillennium” Alumni and parents enjoyed their annual reception and brunch at The Faculty Club after the talks. It was a nice opportunity to reconnect with fellow alumni. Some of us then went on to the Cal vs. Oregon State game, and although the outcome of the game was disappointing, it was great to be among the 63,000 attendees and cheer on our Bears! Our AIChE Alumni Reception was held on November 6 in Salt Lake City, Utah. And the “Alumni of the G. N. Lewis Era” luncheon was held on Thursday, November 15, in the Heyns Room at The Faculty Club. Chemical engineering professor Harvey Blanch entertained and enlightened the alumni with his presentation, “Where Do We Go From Here? Alternative Transportation Fuels Derived from Biomass.” I want to thank all those alumni who have participated in our events, especially in the last six months. Your involvement is important to us, and I look forward to seeing many of you at our future events. We always welcome your thoughts and suggestions for our programs. Goooo Bears! by rebecca zuckerman Fall 2007 Catalyst

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Down from the mountains, down from the ivory tower MOUNTAINEER ARLENE BLUM FINDS A NEW CHALLENGE Arlene Blum calls it her “Rip Van Winkle” moment. It happened in March 2006, almost 30 years after her research with Berkeley biochemist Bruce Ames helped ban mutagenic fire-retardant chemicals from children’s sleepwear. In particular, their seminal papers in Science magazine in 197778 documented the toxicity of chlorinated and bromated versions of a phosphate compound called “tris.”

COURTESY OF ARLENE BLUM

Blum in 1976 with Mt. Everest in the background, from the 18,000 foot Kala Patar. On this American Bicentennial expedition, Blum would climb to camp IV on Everest at 24,500 feet, setting an altitude record for an American woman.

In the 1970s, Blum, a mountain climber who had earned her Ph.D. in biophysical chemistry with Ignacio Tinoco, split her time between research and climbing. When President Reagan took office in 1980, it became clear that the regulation of potentially harmful chemicals was not on the political agenda. Blum decided it was a good time to set aside her research, heed the call of the hills, and depart for a ten-month-long trek across the Himalayan mountain range. In the following decades she led treks to the Himalayas and Australia’s Great Barrier Reef, traveled across the United States giving speeches College of Chemistry, UC Berkeley

and leadership seminars, designed a Nepali language course still used by the State Department, wrote two books, and raised a daughter in her home near the top of the Berkeley hills. Blum’s scientific curiosity and her concern about the environment led her to attend a March 2006 meeting on the emerging field of green chemistry. There she had a conversation with an executive director of the polyurethane foam industry, who began to sketch the structure of some of the chemicals used as flame retardants in foam cushions. Blum looked at the sketch

with a shock of recognition. “I felt like Rip Van Winkle waking up after a 30-year slumber,” she says. “One of the chemicals in the sketch was tris — the same potential carcinogen that had been banned from children’s sleepwear in the 1970s. “What was I supposed to do,” Blum wondered, “just shrug my shoulders and tell them they should read my papers in Science from 30 years ago?” Blum, who blazed trails as a pioneer of women’s mountain climbing, instead decided to take a different route. “It’s pretty obvious that just doing the science on flame retardants isn’t sufficient to affect policy decisions,” she says. “I wanted to use my knowledge and love of chemistry to inform people about these potentially toxic chemicals in their furniture. I decided I wanted to be both a scientist and a policy advisor.” Dual roles for scientists are nothing new. Academic researchers have been called upon for centuries to be scientists and educators. The Bayh-Dole legislation of 1980, named for U.S. Senators Birch Bayh and Robert Dole, allowed universities to patent and license discoveries based on federally funded research. Since Bayh-Dole, university technology transfer and faculty start-ups have skyrocketed, and faculty members are increasingly asked to be both scientists and entrepreneurs. Says Blum, now a visiting scholar at Berkeley’s Center on Institutions and Governance, “Public policy decisions are often based on complicated science. But in the name of objectivity, scientists have backed away from being involved in the policy arena. But if scientists can come down from the ivory tower to be business people, then I think it’s even more important for them to come down to be policy advisors. If scientists are too busy to provide

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to Trisul in 1907. In it she found an accurate description of the dangerous cornice that took Carson’s life. “I was overwhelmed with regret and self-reproach,” Blum later wrote about the event. From that day forward, Blum “wanted to do practical research that would have a direct positive impact on the world. My work would be dedicated to the memory of Bruce Carson. I learned the hard way that good research saves lives.”

Blum arrived in Berkeley in the fall of 1967 and quickly joined the research group of Tinoco, a climber himself who had heard of her abilities and whose office walls were covered with photos of the High Sierra. By the end of 1970 she had passed her Ph.D. qualifying exams and had climbed to the top of Denali in Alaska, the highest peak in North America, as deputy leader of the first team of women to attempt the summit. The decade of the ’70s was a whirlwind of activity. Blum completed her Ph.D. at Berkeley in 1971, and after a 15-month-long round-the-world climbing trip, started a postdoctoral appointment at Stanford in 1973. As part of the U.S. Bicentennial expedition, she climbed to camp IV on Mt. Everest in 1976, setting an altitude record for an American woman of 24,500 feet. In 1978 she led the first American and also first women’s team to attempt Annapurna,

COURTESY OF ARLENE BLUM AND SCIENCE MAGAZINE

their objective expertise, lobbyists are happy to fill the vacuum.” Long before Blum could come down from the ivory tower and her beloved mountains, she first had to learn to climb them. She earned her Ph.D. while simultaneously developing the skills to ascend Denali, Annapurna, and Everest, overcoming both the physical challenges of the mountains and the barriers she faced as a woman. She began climbing as an undergraduate at Reed College, in Portland, OR, in the early 1960s. In her recent memoir, Breaking Trail, she speculates that she craved the focus and camaraderie of climbing to high places. After a lonely year as a graduate student at MIT, where she was one of very few female students in a conservative and hostile environment, Blum happily switched to Berkeley with the help of George Pimentel, who was then the chair of the Berkeley chemistry department.

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Polybrominated diphenyl ethers (PBDEs), used extensively in fire retardants, are chemically similar to known toxins such as polychlorinated biphenyls (PCBs), dioxins and furans.

one of the most dangerous of the 8,000+ meter peaks in the Himalayas. Two members of the team reached the summit, but two more died trying. Blum documented the expedition in her first book, Annapurna: A Woman’s Place. It was another death—the loss of her friend and climbing partner Bruce Carson in 1975 — that did the most to shape Blum’s future and eventually bring her down from the high mountains. While on a deceptively routine climb to the top of an Indian peak named Trisul, Carson fell through the lip of a cornice at the summit. His body was never found. Blum was devastated. When she returned to California, she spotted on her bookshelf a copy of an account of the first expedition

At Berkeley, Blum is working to involve more scientists, especially chemists, in public policy issues. She has also been providing scientific advice on Assembly Bill 706. Sponsored by San Francisco’s Mark Leno, the bill would ban two classes of potentially toxic fire retardants from furniture in California, unless the manufacturer can prove their safety. Los Angeles Times and SF Chronicle editorials endorsed the bill, as did most of the state’s firefighters 27 and environmental groups. Blum recently published a commentary in Science magazine about the fire retardants, and she is organizing a series of meetings to bring together industry, government, and academic experts to discuss how to improve fire safety without relying on potentially toxic chemicals. California began regulating the flammability of furniture and other home furnishings in the aftermath of the 1906 San Francisco earthquake and fire. In the 1980s furniture manufacturers began adding the fire-retardant pentaBDE (member of the family of polybrominated diphenyl ethers) to foam cushions to meet the California standards. In 2003, after reports showing the negative health effects of pentaBDE, the state backtracked and banned the fire retardant. Eight other states and the European Union also banned pentaBDE. In 2004, the U.S. manufacturer voluntarily ceased production. The replacements included chlorinated tris, one of the chemicals Blum and Ames had

Fall 2007 Catalyst

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warned against in the 1970s. AB 706 would ban tris and the other most toxic fire retardants, including PBDEs. “The irony,” says Blum, “is that there is no evidence that California’s mandating the use of fire retardants has improved fire safety. Death and injury from home fires have declined in other states at about the same rate as in California, due mostly to better building codes, smoke alarms, and a reduction in smoking. The new laws in California and other states requiring fire-safe cigarettes will also help a lot to further reduce fire deaths.” California’s very strict standards for fire safety in institutional furniture — furniture used in hospitals, sports arenas and other public places—are often met by using barrier materials and other design advances without

resorting to potentially toxic fire retardants. The institutional standards, unlike the standards for homes, require evaluation of the safety of the piece of furniture as a whole, not its individual components. This gives furniture manufacturers the flexibility to incorporate fire safety into the design of the product, instead of relying on adding possibly hazardous chemicals. No one knows what the long-term health effects are from chronic exposure to PBDEs, tris and other toxic fire retardants. However, a Consumer Product Safety Commission risk analysis suggests 1,200 additional cases of cancer annually from exposure to tris in furniture foam if it were to be used nationally. According to the U.S. Department of Health and Human Services Agency for Toxic Substances and Disease Registry, “Because PBDEs dissolve readily in fat, they can accumulate in breast milk and may be transferred to babies and young children. Exposure to PBDEs in the womb and through nursing has caused thyroid effects and neurobehavioral alterations in newborn animals.” Scientists at the U.S. Environmental Protection Agency found that “cats are highly exposed to PBDEs; hence, pet cats may serve as sentinels to better assess human exposure and adverse health outcomes related to low-level but chronic PBDE exposure.” (Environmental Science & Technology 15 August 2007). They suggest exposure to PBDEs may explain a new epidemic of feline hyperthyroidism. The EPA study points out that “certain regions (such as the state of California) were more proactive in incorporating flame-retardant materials to decrease risk of fire. This may explain the disproportionate increase of hyperthyroid cats at California’s veterinary teaching hospital in the 1980s.”

Blum testing for traces of brominated fire retardants in furniture foam with an x-ray fluorescence analyzer.

College of Chemistry, UC Berkeley

To gauge the extent of the problem for herself, Blum borrowed a portable x-ray fluorescence analyzer and invited acquaintances and neighbors to bring their foam

furniture cushions to be tested. She detected high levels of bromine in her own furniture and in many of the foam cushions she tested. Says Blum, “House cats and human babies share similar environments and habits. Both are exposed to household dust, and some of that gets ingested — cats lick themselves, and babies mouth all sorts of objects. PBDEs are endocrine disruptors. The EPA study finds early evidence that they are related to this mysterious epidemic of hyperthyroid disease in cats. So what are they doing to our kids? We need to find out.” Blum has found her new mountain. The same drive that led her up some of the world’s toughest peaks has motivated her to write, organize seminars, and give presentations to policymakers. As she explains in her commentary in Science (12 October 2007), “Although smoking and fire deaths are rapidly decreasing in the United States, proposed new flammability regulations could add tens of millions of additional pounds of potentially toxic fire-retardant chemicals to bed clothing, pillows, and foam within upholstered furniture. Fire retardant chemicals in our homes should not pose a greater hazard to our health and environment than the risk of the fires they are supposed to prevent.” “Looking back,” says Blum, “I think the problem is that the federal government dropped the ball three decades ago. Just think how much we would know about the safety of fire-retardant chemicals and alternative technologies if the motivation and funding had existed to study them during the last 30 years. But it’s not too late. My training as a chemist at Berkeley is giving me the opportunity to help protect human and environmental health. I’m very grateful and I’m encouraging my daughter, a college sophomore who wants to make the world a better place, to major in chemistry. I am a big fan of green chemistry, and I’m more excited about chemistry now than I ever have been.”

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Class Notes

HARRY SCHEIBER

’35

On the occasion of his 95th birthday last June, E. Morse “Bud” Blue (B.S. Chem) received a certificate of appreciation from the College of Chemistry in recognition of his many years of service. Bud, a lecturer in the chemical engineering department for 30 years, is a long-time and very generous supporter of the college. In 198990, he received the California Alumni Association’s Excellence in Service Award (then called the California Alumni Citation). He was a leader of the fundraising effort for the G. N. Lewis Endowed Chair and is a member of the college’s Alumni Steering Team. A retired manager of invention Assistant Dean Jane Scheiber development at Chevron, Bud regularly attends presents a certificate of appreciation to Bud Blue. college events. He lives in Walnut Creek.

Chester A. Zimmerman (B.S. Chem) is enjoying retirement after a 25-year career as a Naval Engineering Officer and another 25-year career with Lockheed in Sunnyvale. He is currently restoring Franklin classic cars and is active in efforts to bring plug-in hybrids to reality. He comments that he particularly enjoyed the Catalyst profile on John Newman—“He is definitely on the right track!” Chester and his wife, Marlene, make their home in Los Altos, CA.

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Donald J. Simkin (M.S. ChemE) retired from Boeing after 41 years, having worked there through its mergers with McDonnell Douglas and Rockwell. He was head of the Space Shuttle program’s research and development, and he did rocket science for the Apollo program. His name was recently added to Who’s Who in Business & Finance and Who’s Who in Science & Engineering. In the recent past, he cruised the Volga River in Russia and traveled in Poland, Hungary, and the Czech Republic to look at potential chemical investments. He and his wife, Natalie, are residents of Laguna Niguel, CA.

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After a full career in product development at Procter & Gamble, Thomas M. McCarthy (B.S. ChemE) now works as a consultant on environmental problems. In the past ten years, he has worked primarily in Europe as director and senior consultant with Energy and Environmental Management of Dublin, Ireland (while living in Limal, Belgium, with his wife, Monica). He specializes in waste management issues, particularly the recovery of energy and useful materials from waste.

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Manfred G. Reinecke (Ph.D. Chem) retired from a 42-year career at Texas Christian University in Fort Worth, TX, where he is now Emeritus Professor and Cecil and Ida Green Distinguished Emeritus Tutor. With an NIH grant, he is currently working with postdocs on anti-HIV drug research. This year marks his 50th wedding anniversary with his wife, Marlene. They have three children and eight grandchildren.

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Robert O. Hutchins (B.S. Chem), who earned an M.S. at California State University Long Beach and his Ph.D. at Purdue, served as

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head of the chemistry department of Drexel University in Philadelphia, PA, from 1985 to 2000. He received an Outstanding LBSU Alumnus Award in 1987 and the Lindbach Award for Outstanding Teaching in 1980. He plans to retire in 2009. John M. Malin (B.S. Chem), who received his Ph.D. in 1967 from UC Davis, spent his career with the American Chemical Society International Programs until his retirement in 2006. He now enjoys travel, time with his grandchild, and the activities and fellow alums in his local chapter of the California Alumni Association near his home in Arlington, VA.

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Lester S. Andrews (Ph.D. Chem), who earned his doctorate with George Pimentel, was thrilled to receive the 2007 George Pimentel Award for lifetime contributions to the spectroscopy of matrix isolated species, presented in July at the Gordon Research Conference on the Physics and Chemistry of Matrix Isolated Species at Bates College in Lewiston, Maine. He is the author of over 700 research publications, and he was recognized with the Coblentz Award in 1978 and the Ellis R. Lippincott Award in 2001.

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Bernard J. Lilly (B.S. ChemE) retired in August 2006 after a very satisfying 21-year career with ALZA Corporation (purchased by Johnson & Johnson) in Palo Alto and Mountain View, CA. His work centered on scaling bench-size batches of controlled release tablets to full commercial-sized lots. Earlier, he had worked with Stauffer Chemical, Kaiser Cement, and his own dental arts lab. His wife, Elizabeth Sullivan Lilly (M.A. ’67, Art History), and he have lived in Los Altos for almost 33 years, raised three children, and are planning to take their four grandchildren to Europe soon. In retirement he has undertaken

Fall 2007 Catalyst

consulting work and volunteered at his church and a children’s environmental center, besides reading, gardening, hiking, bicycling, and doing all the cooking. He invites fellow alums to get in touch with him at bernardandliz@lillypadsite.com. As a professor of biochemistry and molecular biology at Thomas Jefferson University in Philadelphia, Eric Wickstrom (Ph.D. Chem) studies the visualization and inhibition of cancer gene activity. He and his colleagues recently founded GeneSeen to design nuclear medicine hybridization imaging agents for external genetic profiling of cancer gene activity in tissues, and SecureImplant to design self-protecting medical implants with permanently bonded antibiotics. His wife, Lois, repairs uncooperative computers and writes screenplays. They have four grandchildren, two in California and two in Virginia.

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Gabriel I. H. “Gabe” Kim (B.S. ChemE) has worked at NEC since graduation and was recently named vice president of operations and plant manager of their semiconductor manufacturing plant in Roseville, CA. He saw NEC through a transition from primarily memory products to custom logic products,

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Paul V. Burke (B.S. ChemE) accepted a position this past July with Siemens Water Technologies in San Diego, CA, as their Director of Operations. The company’s main focus is gas scrubbers, adsorption, and biological treatment systems for municipal markets.

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Christopher A. Maines (Ph.D. Chem) lives in Silver Spring, MD, and has what some of us might consider a dream job as a conservation scientist with the National Gallery of Art in Washington, DC. He will give a seminar in December in the college’s physical chemistry seminar series on “Scientific Analysis and Materials Research in the Conservation of Works of Art.”

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Donald E. Bierer (Postdoc Chem) and his wife, Xin Ma, both transferred to Germany as part of the Bayer International delegate program. His wife works in Leverkusen with Bayer AG, while he works at the Wuppertal

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Research Center. They make their home in Düsseldorf. Axel Meyer (Postdoc Chem) has been with Procter & Gamble since 1994, starting in Brussels, Belgium, developing new detergent technologies. In the late 1990s, he spent two years in Newcastle, UK, followed by two years in the U.S. with P&G. Since 2002, he has been in Germany and is currently living in Frankfurt. His daughter, Amalia, was born in February 2007.

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Living in San Jose, CA, David G. Cohen (Ph.D. ChemE) and his wife, Shelli Bodnar, have a four-year-old daughter, Mia, who is fluent in Spanish and English, and a son, Reed, born last August. In 2006, David was elected to the Berryessa school board. His day job is doing computational fluid dynamics modeling in the systems engineering group of Novellus Systems.

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Kristala Jones Prather (Ph.D. ChemE) and Neil S. Renninger (Ph.D. ’02, ChemE), both formerly of Jay Keasling’s research group, were honored by MIT’s Technology Review magazine in its 2007 list of TR35, which recognizes 35 of the world’s top innovators

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and he recently added the production of eight-inch wafers to that of six-inch wafers. He is currently addressing the challenge of continuing to make high-quality products that are cost-competitive.

Left to right Yitman Liang (Ph.D. ’81, Chem) talks with Bruce Stangeland (Ph.D. ’67, ChemE) at the Free Radicals and CHEMillennium alumni era brunch during homecoming. Virginia Schultz (B.S. ’66, Chem) and husband Bill enjoy the brunch. Wayne Sackett (B.S. ’06, ChemE) and Alisa Arunamata show their blue and gold spirit at the brunch! At the Fast Forward to Your Future event held in Tan Hall on September 20, students met to discuss career paths with alums and career center counselors.

College of Chemistry, UC Berkeley

under the age of 35. Kristala is the Joseph R. Mares Assistant Professor of Chemical Engineering at MIT; she was cited for her development of compounds using biological processes rather than chemical reactions— a technique that could avoid harsh solvents and toxic byproducts. Neil, who is co-founder and senior vice president of development at Amyris Biotechnologies in Emeryville, CA, was recognized for his role in engineering microbes to produce lower cost anti-malarials and high-performing renewable biofuels. Also among the TR35 group this year is Berkeley chemical engineering assistant professor Rachel Segalman, who is developing thermoelectric materials to convert heat to cheap electricity—for example, harvesting the heat generated by a laptop to extend its battery life. In May, Neha Harendra Parekh (B.S. ChemE) completed her M.B.A. at New York University’s Stern School of Business, and she was promoted in April to the position of contract account manager for Neutrogena Cosmetics, part of Johnson & Johnson.

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Curt Munson (Ph.D. ’85, ChemE) points to faculty photos on a historic ChemE dartboard. Munson was one of the speakers at the Fast Forward to Your Future event held in Tan Hall on September 20.

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Neil S. Renninger (see 1999)

Daniel J. Fox (Ph.D. Chem) joined the faculty of Suffolk University in Boston, MA, as an assistant professor this fall, teaching organic chemistry in the chemistry and biochemistry department.

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Salmaan H. Baxamusa (B.S. ChemE) wrote last August that he and his wife, Andrea Schmidt, were expecting their first child in September. He is a graduate student in chemical engineering at MIT.

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Megan M. Conley (B.S. ChemE) is a materials engineer at Lockheed Martin Space Systems, in Sunnyvale, CA, testing and developing advanced composite materials for space applications. She is also a parttime student at Stanford, working on a master’s degree in management science and engineering. Last August she spent two weeks in France. Following graduation, Miles W. Carter (M.S. Chem) worked for Samsung in San Jose, CA, doing research and development. This fall he began his studies at the University of Washington School of Law.

’06

Dustin W. Demoin (M.S. Chem) received his M.A. in teaching from Trinity University this year and has begun teaching chemistry at John Marshall High School in San Antonio, TX. Vladislav Goldenberg (B.S. Chem and Physics) has taken a position as a performance engineer with Xcel Energy in Minneapolis, MN.

Daniel J. Haxton (Ph.D. Chem) is currently a postdoctoral research associate in JILA and the Department of Physics at the University of Colorado in Boulder. In July, Ernest W. Kovacs (Ph.D. Chem) started work as a chemist in the biosciences section of General Electric in Niskayuna, NY. Samantha M. Pochert (B.S. ChemBio) took a job in August as a research associate at Fire Cause Analysis in Berkeley, CA. She and her husband, Yevgeniy Lushtak, make their home in Berkeley. Marielle V. Saflor (B.S. ChemBio) has been working with Theravance, in South San Francisco as a research associate in pharmaceutical sciences since last May.

’07

Nerayo Petros Teclemariam (Ph.D. ChemE) accepted a position in September as a member of the technical staff in the systems studies section of Sandia National Laboratories in Livermore, CA.

Fall 2007 Catalyst

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Faculty JAMES C. SMART (Faculty 1974-77)

Former faculty member Jim Smart died August 28, 2007, at the age of 62 of a heart attack following a prolonged battle with non-Hodgkin’s lymphoma. After leaving Berkeley in 1977, he joined the newly formed National Renewable Energy Laboratory in Golden, CO, where he led research on the development of chemical applications of solar energy and biomass utilization and served as group leader of the synthesis and catalysis group and principal investigator in the Department of Energy’s Division of Chemical Sciences. From 1980, he was also adjunct research professor at the Colorado School of Mines. He returned to California in 1988 to join the Jet Propulsion Laboratory in Pasadena as technical group supervisor for electronic materials in the Electric Power Systems Section. In 1991 he began work on intellectual property management, first at the Technology Transfer Office of UCLA and later at Caltech. He published more than 30 papers on various aspects of chemistry. He is survived by his wife, Gretchen, and two sons.

Alumni James T. Biggers (B.A. Chem) passed away on June 24, 2007. Predeceased by his wife, Mary Ann, he was retired from Phillips Petroleum and living in Fresno, CA.

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Edmund G. Carbone, Sr. (B.A. Chem) was born in San Francisco and spent his adult years in the heart of wine country north of the Bay. He and his wife, Ymelda “Peach” Fraser, raised four children and co-owned and operated the Carbone Napa Valley Winery, living in Napa and Yountville. A lifelong “Bear Booster,” in his later years he took satisfaction in gardening. Ed died July 17, 2007, at the age of 94 and is sur-

College of Chemistry, UC Berkeley

vived by his daughters, Judy, Carol, and Mary, and his son, Edmund, eight grandchildren, and ten great-grandchildren. Herbert E. Carlson (B.S. Chem) started work for Adhesive Products in Albany, CA, in 1934 and retired in 1962 as chief chemist. For the next decade, he was a consultant to the research and development department of the Union Lumber Company in Fort Bragg, CA. Following his 1973 retirement, he lived in Nevada City, CA, until his passing on July 5, 2007. We are grateful for the support he gave to the College of Chemistry. Scott E. Wood (Ph.D. Chem) started as a research assistant at MIT and went on to become associate professor at Yale, working on the Manhattan Project during World War II. From 1954 to 1980, he was on the faculty of the Illinois Institute of Technology (IIT) in Chicago, also serving IIT in many administrative capacities. While he was at IIT, Argonne National Labs recruited him as a research associate and a consultant, and he consulted for Exxon Nuclear and the Aluminum Corporation of America, as well. He co-authored two books, Thermodynamics—An Introduction and The Thermodynamics of Chemical Systems; was associate editor of the Journal of Chemical Physics, and was an abstractor and later section editor of Chemical Abstracts, as well as serving on the Advisory Board of Higher Education for the state of Illinois. A resident of El Paso, TX, following his retirement, he passed away on June 7, 2007, at the age of 97, preceded in death by Marie, his wife of 65 years, and survived by his son.

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Stephen A. Bordi (B.S. Chem) passed away on April 9, 2007.

George R. Negishi (Ph.D.; B.S. ’30, Chem) was retired from Nippon Oil Co. and living in Tokyo, Japan. A supporter of the College of Chemistry, he stayed in touch with fellow

alums, including Scott E. Wood (Ph.D. ’35, Chem). His wife, Ryoji, let us know that George passed away on September 13, 2006. A San Francisco native, VirginiaJane (Newman) Harris (formerly Glaedell) (B.S. Chem) earned an M.A. from San Francisco State College and worked at Shell Oil through WWII. Following the war, she taught high school chemistry and, in 1962, completed an M.A. and a teaching credential at Stanford. She joined the faculty of American River College initially as a chemistry professor and later was a math professor. As a single mother, she dedicated herself to her son, Thomas, and her students, and was an avid naturalist who loved hiking, skiing, swimming, photography, and travel. After her retirement in 1984, she made her home in Diamond Springs, CA. Having broken the barrier against female chemists herself, she would often invite a current female graduate student to join her at some of the G. N. Lewis Era Luncheons. She passed away on July 22, 2007, at the age of 89, survived by her son, seven grandchildren, and seven great-grandchildren.

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Saverio M. Cimino (B.S. Chem) retired from FMC Corporation in 2000 after 43 years of service. He and his wife, Margaret, made their home in Southern Pines, NC, before his passing on March 1, 2007.

’39

A native San Franciscan, Maurice P. Stergios (B.A. Chem) was raised in Tahiti, then returned to San Francisco for high school and to attend UC Berkeley. He worked as a chemist for Aramco in Saudi Arabia but came back to San Francisco in 1953 and opened the French restaurant “Place Pigalle.” He sold the restaurant in 1976, continuing to work as a consultant for restaurateur Al Scoma. He passed away on August 19, 2007, survived by his wife, Kathleen, and his stepdaughter, Andrea Cannon.

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William H. McNeely (B.S. Chem) earned a Ph.D. in Chemistry from Caltech and did postdoctoral research at Ohio State University. In 1944, he went to work for Kelco Company in San Diego (later a division of Merck), where, in 1969, he spearheaded research and development that led to the commercial use of xanthan gum in a wide array of consumer products and industrial

Professor Daniel E. Koshland Jr., (B.S. ’41, Chem) esteemed alumnus of the College of Chemistry and long time professor of molecular and cell biology, died on July 23, 2007, at the age of 87, following a massive stroke. Koshland, who received his B.S. in chemistry in 1941, served on the college advisory board for many years.

’41

“Dan Koshland was both a beloved alumnus and an invaluable member of the college advisory board,” said Dean Charles Harris. “Personally, I will be forever indebted to Dan for his guidance and support all these years. Like so many of his friends and colleagues, I will simply miss him and all the good things he stood for. He was unique.” An insightful scientist known for his work on proteins and enzymes, Koshland achieved the status of scientific statesman during his 10 years, from 1985-1995, as editor of Science. In what Koshland described as “one of the high points of my life,” he spearheaded the large-scale reorganization of biology at Berkeley in the 1980s, pruning or merging eleven small departments into three. The reorganization, accompanied by a fundraising campaign, placed UC Berkeley in a leadership role in the biological sciences. In recent years, Koshland guided the campus’s $400 million Health Sciences Initiative. Because of his vision, Stanley Hall, the new laboratory facility for interdisciplinary bio-

applications, for which he received the National Industrial Achievement Award. He founded Ara Chem in 1960 and collaborated with the Navy to develop a water-based oil spill dispersant that resulted in safer oilspill cleanups. He retired in 1980 as Kelco’s vice president of research and development, having written more than 50 scientific papers and obtained more than 30 patents. As an environmentalist and owner of a 150-acre ranch near La Mesa, CA, he took pride in supporting responsible use of land and water resources. He also took up

research into issues relating to world cultures, religions, and the future of American democracy, which led to the publication, in 2005, of his book, Hi-Lites of Philosophy and Theology. He died on August 20, 2007, at the age of 92, survived by his wife, Rita, four daughters, two sons, four grandchildren, and five great-grandchildren.

science teaching and research, opened this fall.

Following Marian’s death in 1997, Koshland reconnected with Yvonne Cyr San Jule, whom he had first met in 1940 when they were undergraduates. They married in August 2000.

Koshland never forgot his roots in the College of Chemistry. In addition to his work with the advisory board, he recently established an endowment in the chemistry department. He consistently attended the Alumni of the G. N. Lewis Era luncheons and other events. He was a recipient of the National Medal of Science in 1990, a Lasker Award for Special Achievement in Medical Science in 1998 and the Welch Award in Chemistry in 2006, in addition to the Berkeley Citation, the Berkeley Medal, the Clark Kerr Award, and the Alumnus of the Year award. As a young man, Koshland enrolled in Berkeley. He immediately joined the Manhattan Project group headed by Glenn Seaborg to isolate plutonium for an atomic bomb, following Seaborg to the University of Chicago and eventually to Oak Ridge, TN. At the University of Chicago, Koshland met Marian Elliott, whom he married in 1945. In 1946, he returned to Chicago and stayed to complete his Ph.D. in organic chemistry in 1949. After two postdoctoral years at Harvard University, the Koshlands moved to Long Island to work at Brookhaven National Laboratory, where they remained until 1965, when they were recruited to the Berkeley faculty.

Aldred J. Simmons (B.S. Chem), who was president and chairman of the Metals Mining Company in Houston, TX, passed away on July 21, 2007. He is survived by his wife, Cora.

Koshland is survived by his second wife, Yvonne Koshland; two sons and three daughters; and two sisters, Francis K. Geballe of Woodside and Phyllis K. Friedman of Hillsborough. He also is survived by three stepchildren, nine grandchildren, 12 stepgrandchildren, one great-grand-daughter and 17 step-great-grandchildren. One of his daughters-in-law, Catherine Koshland, is UC Berkeley’s vice provost for academic planning and facilities. Donations in Koshland’s memory can be made to the Marian Koshland Science Museum, 500 Fifth Street, NW, Washington DC, 20001, or to the UC Berkeley Foundation to support bioscience and energy teaching and research. Write to the UC Berkeley Foundation, Attention: Vice ChancellorUniversity Relations, 2080 Addison Street, #4200, Berkeley, CA 94720-4200. based in part on press release by robert sanders, media relations

Fall 2007 Catalyst

ROBERT HOLMGREN

’40

Robert H. Kimura (B.A. Chem) passed away on July 10, 2006.

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Glen F. Bailey (B.A. Chem) passed away on July 24, 2007. A resident of Richmond, CA, he had worked for the U.S. Department of Agriculture in Albany as a research chemist.

’41

Lowell W. Bradford (B.S. Chem) passed away on April 12, 2007. His agency, L.W. Bradford Forensic Scientist, in San Jose, CA, provided consulting in physical evidence. Edward R. Brown (B.A. Chem) earned his J.D. at Loyola Law School in 1963 and practiced real estate law with his own firm in Oxnard, CA. He passed away on January 1, 2007.

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We have just learned from Mary Wahl that her husband, Arthur C. Wahl (Ph.D. Chem), passed away on March 6, 2006. While a graduate student at Berkeley, he worked with Glenn Seaborg on the research that led to the identification and naming of plutonium. He also purified element 93, neptunium. From 1943 to 1946, he led the research in plutonium chemistry at Los Alamos, developing the purification procedures that were central to the success of the Manhattan Project and were used for years afterward on an industrial scale. After the war, he was recruited to teach in the chemistry department at Washington University in St. Louis, where he led both the inorganic and nuclear chemistry groups for almost four decades. His two long-standing interests were in oxidationreduction chemistry and fission yields. In 1991, he moved back to Los Alamos and continued to do research, publishing his last fission compilation in 2005. John W. Gofman, M.D. (Ph.D. Chem), renowned for his pioneering work in identifying lipoproteins and their relationship to cholesterol levels and their effects on human health, passed away in San Francisco on August 15, 2007, at the age of

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College of Chemistry, UC Berkeley

88. He will also be remembered for his relentless research into the effects of lowlevel ionizing radiation in humans and his successful efforts to force the federal government to drastically revise standards for radiation exposure, limit nuclear tests, and cancel projects that use nuclear explosives for digging harbors and canals. In his lifetime, he called for a moratorium on the licensing of new nuclear power plants until the public health consequences could be studied, and he pressed doctors to reduce unnecessarily high doses of x-rays. His Ph.D. research was done with Glenn Seaborg, after which he worked on the Manhattan Project during WWII. Gofman earned an M.D. in 1946 from UC San Francisco and, in 1947, joined the Berkeley faculty in the Division of Medical Physics of the Department of Physics, where he formed the lipoprotein laboratory in the Donner Laboratory. During the 1960s, at the urging of Glenn Seaborg, then chair of the Atomic Energy Commission, he started a biomedical division at the Livermore Radiation Lab (LRL) to study the effects of ionizing radiation on human health. He resumed his professorship at UC Berkeley in 1971, retiring from the University in 1973. He continued to challenge the established view that there is a threshold below which radiation is safe, having founded in 1971 the Committee for Nuclear Responsibility, a nonprofit educational and research organization, which he chaired until his death. In 1992 he received the international Right Livelihood Award “for his pioneering work in exposing the health effects of low-level radiation.” Predeceased by his wife, Helen, he is survived by his son, John, and his longtime colleague and friend, Egan O’Connor. Fred R. Stevenson (B.S. Chem) passed away on July 22, 2007. He owned his own

company, Stevenson Equipment, in Santa Rosa, CA, where he and his wife, Georgia, made their home. James R. Wilson (B.S. Chem; Ph.D. ’52, Physics) passed away on August 14, 2007. He had worked at Lawrence Livermore National Laboratory as an astrophysicist. He and his wife, Demetra, made their home in Livermore, CA. Robert R. Grinstead (B.S. Chem) died August 7, 2007, in Davis, CA, at the age of 84. Following graduation, he spent three years in the Army Signal Corps and then enrolled at Caltech, where he obtained a Ph.D. in chemistry and met and married his wife, Helen Stabler. The couple moved to Walnut Creek, where he started his 40-year career at Dow Chemical Company, doing research in such diverse fields as mining and mineral processing technology, the removal of nitrogen oxides from stack gases, the removal of magnesium from salt brines, and the oxidation of vitamin C. He published scholarly articles in a variety of chemical and environmental journals, was editor for 16 years of The Vortex, the publication of the California section of the ACS, and received the California ACS’s Peterson Award for service to the Society. His lifelong conviction that scientists were not exempt from the obligation to put effort and resources into solving problems faced by society led him to write a weekly syndicated newspaper column during the 60s and 70s and to serve as chairman of the California Friends (Quakers) Committee on Legislation. Helen, his wife of 57 years, died in 2006; he is survived by two sons, a daughter, and two grandchildren.

’46

Anne Marie (Anderson) Greensfelder (B.A. Chem), a fourth-generation San Franciscan, had wanted to be a fashion designer, but her father died when she was

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13, so she studied chemistry to better support her mother and younger sister. She worked for Shell Development as an abstract writer in their chemical library in Emeryville, where she met her husband, Bernard S. Greensfelder (Ph.D. ’28, Chem), who passed away in 1968. She was politically engaged, a lifelong environmentalist and a bird lover, and she wrote legislative alerts for the Golden Gate Audubon Society’s newsletter. Fascinated by outer space, she would have liked to be on the first commercial space flight but was deterred by the $10 million cost. She passed away February 28, 2007, in Berkeley at the age of 81, survived by a daughter, a son, and a stepson. Robert L. Oswalt (M.S., B.S. ’44, Chem; Ph.D. ’61, Linguistics) will be remembered for his contributions to the preservation of the endangered languages, stories and songs of Northern California’s Pomo Indians. A nature lover, he and his wife of 55 years lived at the edge of Tilden Park in Kensington, CA, where he grew hundreds of species of plants. For decades, he worked on compiling dictionaries of three distinct Pomo languages: Kashaya, Central, and Southern Pomo. Although he held back their publication, hoping to perfect and publish them himself, linguists are now expressing great interest in completing the dictionaries for publication. The son of an Army doctor, Oswalt lived in the Philippines with his family before studying chemistry at Berkeley and serving in the Navy during World War II. His Ph.D. in linguistics was on the Pomo language and culture and, in 1964, he published Kashaya Texts, containing stories he collected from the remaining native speakers of a Pomo tribe on California’s Sonoma coast. He was also founder and president of the nonprofit California Indian Language Center. He died on May 22, 2007, survived by his wife, Esther, two sons, and a granddaughter.

Richard G. Breuer (B.S. Chem) passed away on August 11, 2007. He had retired from Kaiser Aluminum and Chemical Corporation as a senior research associate, and he had patented a method for utilizing partially calcined alumina as a precipitation aid in the Bayer process. He and his wife, Beverly, made their home in Lincoln, CA.

’48

We learned from Manfred Lindner (Ph.D. ’48, Chem) that Louis Werner (Ph.D. Chem) died from pancreatic cancer on May 20, 2007, at age 88. He started graduate work at Berkeley in 1940, but with the advent of WWII, he joined Burris Cunningham at the Metallurgical Laboratory at the University of Chicago, working under Glen Seaborg to isolate the new element number 94, plutonium. Werner and Cunningham succeeded in isolating and weighing the first visible quantity of the new element. He continued his work with plutonium at both Oak Ridge, TN, and at the Hanford facility at Richland, WA. Returning to Berkeley in 1946 to work on his Ph.D. in Chemistry, Werner isolated another new transuranium element, curium, element number 96. He subsequently became director of fallout studies at the U.S. Radiological Defense Laboratory in San Francisco, but after ten years decided to pursue peaceful uses of atomic energy and became the AEC’s representative to the U.S. embassy in England, a post which lasted several years. Upon return to the United States, his work included studies of the impact of commercial nuclear power plants and alternative energy sources. Survivors include two children, Craig and Melinda, and four grandchildren. Stanley L. Miller (B.S. Chem), an emeritus professor of chemistry and biochemistry at UC San Diego, died on May 20, 2007, at the age of 77. He will be remembered for his famous laboratory experiments in 1952,

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while a graduate student at the University of Chicago, which demonstrated how the simple organic compounds considered necessary for the origin of life could have been synthesized on the primitive Earth. He put water and ammonia into a flask with hydrogen and methane gas, boiled the solution and zapped the contents with an electrical discharge to simulate lightning and coronal discharges in the atmosphere, producing a “molecular soup” containing amino acids, the building blocks of proteins and of life itself. After earning his doctorate from the University of Chicago in 1954, he was a postdoc at Caltech and Columbia University before joining the faculty of the newly formed UC San Diego campus. There he continued his research into the chemical origins of life for over four decades and helped to establish the university’s tradition of interdisciplinary research. A member of the National Academy of Sciences, he received the Oparin Medal from the International Society of the Study of the Origin of Life in 1983 and was president of the society from 1986 to 1989. Charles P. Nash (B.S. Chem) received his Ph.D. from UCLA in 1958 and joined the chemistry faculty at UC Davis, where his expertise was in physical chemistry. A member of the American Chemical Society and the American Physical Society, he received UC Davis’s Distinguished Teaching Award in 1978. In addition to chairing the Davis Division of the UC Academic Senate for two terms, he led and served the campus in many administrative capacities, even after his retirement. He was also on the board of directors for the League of Women Voters of Davis, secretary of the Davis Chapter of Sigma Xi and treasurer of the UC Davis Emeriti

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Fall 2007 Catalyst

Association. He passed away on July 15, 2007, at the age of 75, predeceased by his first wife, Lois Brown Nash, who died in 1999, and survived by his second wife, Clinton Congdon Nash, three children from his first marriage, three stepchildren, and five grandchildren. He was a generous supporter of the College of Chemistry and a regular attendee at college events. Howard L. Petersen (B.S. Chem) passed away on April 7, 2007. He started his own company, Petersen Scientific in Saratoga, CA, and continued to serve as its president and CEO until his death. He made his home in Saratoga, CA, with his wife, Gloria.

L. E. “Skip” Scriven (B.S. ChemE), a longtime member of the college’s advisory board, passed away on August 3, 2007. His long and prolific career included pioneering research in fluid mechanics, interfacial phenomena, coating processes, porous media and surfactant technologies. He earned his Ph.D. degree from the University of Delaware in 1956 and went to work for Shell Development Company in Emeryville, CA, as a research engineer. In 1959, he joined the faculty of the University of Minnesota, eventually becoming Regents Professor of Chemical Engineering and Materials Science in 1988. Besides his research, his legacy includes the outstanding mentoring of more than 100 graduate students, many of whom became leaders in their field. He authored more than 400 journal publications and served as consultant and advisor to many major companies and organizations, as well as receiving numerous honors and distinctions from AIChE, ASEE, ACS, and the University of Minnesota. Elected to the National Academy of Engineering in 1978, he served on several national committees setting priorities for chemical engineering and materials science research. He and his wife, Dorene, who survives him, lived in Minneapolis.

College of Chemistry, UC Berkeley

Donald J. Peterson (B.S. ChemE) passed away on August 22, 2007. He had worked for Coastal Oil in Westville, NJ, and made his home in Cherry Hill, NJ.

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Robert H. Iwamoto (B.A. Chem and Biochem) and his wife, Gene, were very engaged with the College of Chemistry, supporting the Henry Rapoport Chair and attending events. He worked for SCM Corporation, and they made their home in Palo Alto, CA. He died of cancer on September 7, 2007. He is survived by his wife; their son, who is a radiologist; and two grandchildren.

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Elizabeth M. Monty (B.S. Chem) passed away on June 7, 2007. She and her husband, David, made their home in Sunland, CA. Linda L. Saylor (B.A. Chem) lived in Mill Valley, CA, prior to her death on August 27, 2007.

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Larry R. Doyle (M.S. Chem) passed away on August 20, 2007.

Robert P. Mandal (Ph.D. Chem) died on June 23, 2007, while on an expedition to the Amazon jungle. During his interesting and varied career, he directed research and development at Aerojet General, Applied Technologies, Lockheed, Teledyne, Litton, Silicon Valley Group, Applied Materials, and ASML. Instrumental in developing technologies key to the defense and microelectronics industries, he also played an important role in developing the technology used in the camera that took pictures of the surface of Mars. He co-authored numerous patents and publications in the field of microelectronics technology, and he chaired many symposia and served as referee for several professional journals.

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He is survived by his wife, Barbara, two sons, a daughter, and three grandchildren. Andrew W. Raczkowski (Ph.D. Chem) passed away on August 31, 2007. He had been the manager of data communications and a product engineer for Western Digital Corporation in Irvine, CA.

’75

Robert M. Moore, Jr. (Ph.D. Chem), a long-standing supporter of the college, spent his career at Ethyl Corporation in Baton Rouge, LA, and continued there when it became Albemarle. He passed away on January 7, 2007, survived by his wife, Jennifer.

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Staff Viola T. “Teri” Doizaki served as administrative assistant to George Pimentel in the 1960s and as Management Services Officer for the Department of Chemistry from the mid1980s to the mid-1990s. We were saddened to learn that she passed away on June 17, 2007. Teri had been working with Jeanne Pimentel on the George Pimentel Archive Project at the time of her death. Remembered by all who knew her as a kind, enthusiastic, generous person whose mission in life was to be of service to others, Teri will be greatly missed. She was living in Albany, CA, prior to her passing, and is survived by one sister and three brothers. compiled by dorothy read

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of private giving

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College of Chemistry University of California, Berkeley

message message from from the the dean dean

U.C.

Berkeley, with its outstanding students and depth and breadth of excellence, is widely recognized as one of the best places in the world to do chemistry and chemical engineering. This fact helps us to attract and keep highly talented faculty members, but it is also the reason that other prestigious institutions pursue our faculty, attempting to lure them to their ranks.

They are here — continuing to design and teach new undergraduate courses, mentor graduate students and postdocs, and, of course, conduct cutting-edge research in such areas as energy, health, and the environment. Every gift is important, and to each of our donors, I extend warmest thanks. Gifts to the College of Chemistry totaled more than $6 million in fiscal year ’06-’07, including $1.6 million in endowment that will provide a base of permanent funding for the future.

Elsewhere in this publication (see p. 3), I mention the large number of faculty retention cases that we have had in the past several years. Our success in keeping so many individuals who received attractive outside offers highlights the crucial importance of having the financial resources available to mount a significant retention effort. Our ability to preserve and develop the excellence of our faculty depends in no small measure on you, our alumni and friends — individuals, corporations and foundations — whose generous gifts help to support our students, fund research, renovate facilities, purchase equipment, and enrich the intellectual life of the college community.

Among the most notable gifts were a commitment of $400,000 from the Pitzer Family Foundation that will enable us to expand the Pitzer Center and to upgrade its information technology; a gift from Professor Daniel Koshland, who shared his Welch Prize money with us shortly before he passed away; pledge payments for endowed professorships from Bard and Gene Howe, Larry and Diane Bock, and an anonymous donor; a bequest from Jonathan Powell (B.S. ’37); a charitable remainder unitrust from Warren Clifford (B.S. ’51, M.S. ’52) and Erna Clifford; an anonymous gift for an endowed graduate support fund; and a challenge grant from Zaiga and Joon Moon (Ph.D. ’64), completing the Theodore Vermeulen Chair in Chemical Engineering.

Thanks in part to your generosity, talented faculty members in a variety of fields, ranging in age from their 30s to their 60s, have opted to stay at Berkeley when they could have gone elsewhere.

Also deserving special mention are the faculty members who established endowed funds for graduate support this year. We now

College of Chemistry, UC Berkeley

f i n a n c i a l s

35.58% 46.15%

18.27%

S O U R C E S O F P R I VAT E F U N D S Individuals

$2.864 M

46.15%

Corporations/Corporate Foundations $2.208 M

35.58%

Private Foundations/ Nonprofit Organizations

$1.134 M

18.27%

Total

$6.206 M

100.00%

14.37%

16.32% 68.91%

have a total of 14 such faculty members who have made gifts that will be matched dollar for dollar by the Chancellor, thus doubling their initial value. These individuals “give at the office,” and they give again — testimony to our faculty’s own faith in the outstanding quality of the college. About half of our private support is from foundations and corporations. Particularly generous commitments this year came from the American Cancer Society, Bristol-Myers Squibb, the Burroughs Wellcome Fund, the Camille and Henry Dreyfus Foundation, Eli Lilly and Company, Gilead Sciences, the Jane Coffin Childs Memorial Fund, Lam Research, Novartis, and Rohm and Haas.

U S E S O F P R I VAT E F U N D S [ E N D O W M E N T ] Chairs

$1.116 M

68.91%

Student Support

$0.264 M

16.32%

Unrestricted

$0.233 M

14.37%

Instruction/Seminars

$0.006 M

0.40%

Total

$1.619 M

100.00%

As I say in my column at the front of this journal, I have been continually inspired as I’ve come to know the community of alumni and friends who contribute so essentially to the college’s mission. Please know that all gifts, no matter their size, are deeply appreciated. Your investment in the college yields dividends to our students, our faculty, and our society, and for that we are truly grateful.

8.75 % 12.99 %

15.74%

60.62%

U S E S O F P R I VAT E F U N D S [ O P E R AT I N G ] Research

$2.781 M

60.62%

Student Support

$0.722 M

15.74%

Unrestricted

$0.596 M

12.99%

$.401 M

8.75%

Capital Instruction/Seminars

$0.087 M

1.90%

Total

$4.587 M

100.00%

annual report ’06-’07

donors to the college

Membership in the Dean’s Associates is accorded to donors of $5,000 or more. The College Council recognizes donors of $100 or more.

The California Benefactors and the Dean’s Associates

The Blue and Gold Society and the Dean’s Associates

The California Benefactors contribute $1 million or more over their lifetimes and are members of both the Dean’s Associates and the College Council.

Blue and Gold Society members make cumulative gifts of $500,000 or more. They are also members of both the Dean’s Associates and the College Council.

Anonymous Norbert C. and Florence M. Brady Nirmal and Ellen L. Chatterjee Chen Yu-How T. Z. and Irmgard Chu Aldo DeBenedictis Estate Dr. Melvin J. Heger-Horst Trust Mr. and Mrs. Hubbard C. Howe, Jr. Gunawan Jusuf Ross McCollum Trust Jean Mosher Pitzer Pitzer Family Foundation Warren and Katharine Schlinger Foundation Ann E. Shiffler Estate Robert Tsao

Anonymous Larry and Diane Bock Chen He Tung Dr. James O. Clayton Estate Erna P. Clifford Warren E. Clifford Dr. and Mrs. Gus D. Dorough, Jr. Henry F. Frahm Estate Richard M. and Lillian Lessler Irma McCollum Trust Dr. Reid T. Milner Trust Beatrice Thomas Estate Marie W. Woodward Estate

The 1868 Society and the Dean’s Associates The college’s 1868 Society, named for the year in which the university was chartered, acknowledges individuals whose cumulative gifts to the college are $100,000 or more. They are also members of both the Dean’s Associates and the College Council. Anonymous (2) Usman Atmadjaja Leo A. Berti Estate

College of Chemistry, UC Berkeley

Bud Blue Thelma Buchanan Estate Sunney I. Chan Chng Heng Tiu Fannie L. Chong Chester W. Clark Estate Frank and Janice Delfino Dr. Sam H. Eletr William and Janet Gerhardt Suhargo Gondokusumo G. Douglas and Regina Gould Prof. and Mrs. John E. Hearst Robert and Yasuko Ikeda Stephen T. Isaacs and Kathryn Macbride Harold and Mary Ella Johnston Kiong Yo Kian Engr. Joseph L. and Dr. Helen C. Koo Prof. Daniel E. Koshland, Jr. Joseph M. Kunkel II Lee Sheng Peng Annie L. Li Liem Sioe Liong Wesley and Elizabeth Lindsay Estate Tony K. and Louisa Ling Lie Shiong Tai Prof. Bruce H. Mahan Estate Dr. and Mrs. Joon S. Moon Dr. Robert N. Noyce S. M. “Jack” Olsen Marjorie Pape Crandall Pearce Jonathan S. Powell Dr. Mochtar Riady Klaus and Mary Ann Saegebarth J. A. Sanford Mr. and Mrs. John W. Scott, Jr. Patricia McAdams Schreter William H. Shiffler Dr. Charles E. Stehr Tan Keong Choon Henry K. Tom Dr. and Mrs. James R. Tretter

Mrs. Theodore Vermeulen Doris H. Welles Estate Eka Tjipta Widjaja Charles R. Wilke Estate Eugene T. C. Wu

The California Associates and the Dean’s Associates The California Associates made commitments of $50,000 or more this year to the college. They are also members of both the Dean’s Associates and the College Council. Anonymous (2) Larry and Diane Bock Erna Clifford Warren E. Clifford Mr. and Mrs. Hubbard C. Howe, Jr. Prof. Daniel E. Koshland, Jr. Dr. and Mrs. Joon S. Moon Pitzer Family Foundation Jonathan S. Powell

The Berkeley Associates and the Dean’s Associates The Berkeley Associates made commitments of $10,000-$49,999 this year and are members of both the Dean’s Associates and the College Council. Anonymous Dr. and Mrs. David Altman Atkinson Family Foundation Bud Blue

* New donor(s) in 2006–2007

Robert J. Carr Nirmal and Ellen L. Chatterjee T. Z. and Irmgard Chu Robin D. Clark and Mary Mackiernan Nancy G. Curme Dr. and Mrs. Gus D. Dorough, Jr. Jamie and Jennifer Doudna Cate* William E. Fogle and Marilyn Wun-Fogle Kai-Ye Fung Drs. Thomas R. Gadek and Katherine Neldner Gay Chemists Support Fund William and Janet Gerhardt Clayton Heathcock and Cheri Hadley Robert and Gene Iwamoto David G. Karraker Ed Kim Engr. Joseph L. and Dr. Helen C. Koo Arturo Maimoni Prof. Samuel and Mrs. Lydia Markowitz T. W. Newton Carlos and Patricia Nuila Norman and Paula Phillips Eugene B. Reid Ferenc E. Rosztoczy J. A. Sanford Richard Saykally and Chris Read Warren and Katharine Schlinger Foundation Patricia McAdams Schreter Hugh C. Silcox Judith and Gabor Somorjai Dr. Charles E. Stehr Richard M. Teeter David and Lieselotte Templeton Dr. J. A. Trainham and Dr. L. D. Waters Willard M. Welch

The Gold Sproul Associates and the Dean’s Associates

The Blue Sproul Associates and the College Council

The Gold Sproul Associates made commitments of $5,000-$9,999 this year and are members of both the Dean’s Associates and the College Council.

The Blue Sproul Associates made commitments of $2,500-$4,999 this year and are members of the College Council.

Edwin D. Becker Ardra C. Brodale William A. Daniels Tom and Marty De Jonghe Frank and Janice Delfino Drs. Thomas J. Dietsche and Laura J. Dietsche David and Wena Dows Dr. and Mrs. Theodore H. Geballe Victor W. Huang* Dr. and Mrs. Andrew Kaldor Andrea L. Keaton Luisa T. Molina Albert Narath Joan Friedman Newmark and Richard Newmark Christine G. Powell Constance M. Ruben Karen and Scott Sibbett Mr. and Mrs. John R. Skinner Barbara A. Tenenbaum Michael G. Valentine

Robert and Wendy Bergman John H. Birely Tim and Valerie Bruemmer Fannie L. Chong Pete Dragovich and Pei-Pei Kung Dr. Julianne Elward-Berry Drs. David S. Gee and Caryn C. Lum Vic and Faye Gunther Charles B. Harris H. Ross Hawkins John F. Heil Michael C. Kavanaugh and Carol R. James Prof. and Mrs. C. Judson King William A. Kleschick Polam and Marcia Lee Virginia and Frank Lew Michael J. and Janet Kim McCormick Tim Montgomery Herb Nelson Rodney and Jeanne Panos William R. Parrish Darwin and Donna Poulos Lanny Replogle Klaus and Mary Ann Saegebarth Drs. Steven Sciamanna and Sandy J. Roadcap Manesh and Margarita Shah Clinton D. and Sharon Snyder Kong-Heong Tan Neil Tomson* George K. and Stephanie D. Tyson

Mrs. Theodore Vermeulen Alex Wernberg Rita Wieland Stephen Worland

The Robert Gordon Sproul Associates and the College Council The Robert Gordon Sproul Associates made commitments of $1,000-$2,499 this year and are members of the College Council. Anonymous Arthur and Frances Abramson Profs. Juana V. and Andreas Acrivos Stuart and Sarah Adler Keith and Elaine Alexander Lester Andrews Myron and Barbara Andrews Ron and Sue Banducci David Bass Richard Behrens William and Inez Benjamin Dr. Tom A. Bither, Jr., and Mrs. Margaret V. Bither M. Robert Blum Robert G. Brinkley Michelle Brodale Dave and Donna Brown Charles Buse John B. Bush, Jr. William H. Calkins Joseph and Susan Cerny Edmund Chambers David C. K. Chan Sunney I. Chan Uma and Kumar Chandrasekaran Cecil C. Chappelow

annual report ’06-’07

donors to the college The Robert Gordon Sproul Associates and the College Council, continued

Margaret and Nai Chen Tan-Jen and Li-Fong Chen Ronald L. Clendenen Robert S. Crowder Bruce Darling* Eric P. Darmstaedter Thomas and Cynthia Delfino Walter and Eleanor Dong David and Klara Dorsey Clelland R. Downs Dean C. Draemel Daisy Joe and Justin Du Bois Dr. Victor H. Edwards Helen M. Elliott Gail G. Engerholm Virginia and Larry Faith Steven and Terri Fantazia Helene V. Fatt Michael and Mary Flaugh David B. Fraser* Friends of Eric Abramson Scholarship Fund Shun C. Fung Man K. Go Mr. and Mrs. Wataru Goishi Edward D. Goldberg Charles Goss G. Douglas and Regina Gould Elaine and Arnold Grossberg Ronald Grzywinski* Margaret Gwinn Eric Haas* Dr. Barry Hart and Ms. Kathleen McNutt-Hart Jessie Herr Joel Hill Herbert Hooper Irma Hrycyk Hsin-Yuan Hu Richard W. Hyman Yasuko Ikeda Mark J. and Alice H. Isaacson Bala and Kumari Iyer John Jost, Jr. Dr. Max J. Kalm Kiyoshi and Irene Katsumoto Stanley Kelly

College of Chemistry, UC Berkeley

Mr. and Mrs. David E. Kepler II Hyunyong Kim Ronald and Coleen Kino* Mr. and Mrs. Fred Kirby Kevin A. Klotter Janell Kobayashi Henry F. Koopmann LaRoc and Linda Kovar James and Barbara Lago Julian I. Landau Peter W. Lee Philip M. Lessner Marc and Tsun-Tsun Levin David Lieu, M.D., M.B.A. David A. Lightner Dr. and Mrs. Nelson Lin Robert and June Lindquist Liming M. Linger Dick and Myra Lynch Scott and Annette Lynn Gary and Irene Masada Thomas A. Massaro, M.D. Richard and JoAnne Mathies Larry and Debbie Meisner Thomas J. Meyers Dr. Michael J. Miller Drs. Walter H. Moos and Susan M. Miller Merrill A. Muhs Roberta N. Mulford Curt Munson and Hazel Olbrich Charles and Clinton Nash Chin-Tzu Peng Dr. Donald D. Phillips Llad Phillips Jeanne Pimentel Jacob J. Plattner Prof. and Mrs. John M. Prausnitz Jack and Daisy Yep Quan John A. Ragan R. Andrew Ramelmeier Gregor Riesser Milton H. Ritchie John L. Robbins Scott Rocklage Steve R. Roffler and Bing-Mae Chen David Sable

Marsha Sable William Sailor, Ph.D. Elmer E. Schallenberg Gary P. Schwartz Ronald E. Silva Edward R. Simmons Sher G. Singh Robert and Betty Smitherman* Tonny Soesanto and Fay Sampoerna Jeffrey P. Solar and Rosalyn Furukawa Ellen Lee and Michael Solomon Thomas M. Stachelek* Bruce E. and Susan J. Stangeland Donna R. Sterling Dr. Doris Stoermer Therese W. Sze* Jerome H. and Selma E. Targovnik Anne Friend Thacher Curtis Tong Constantine Tsonopoulos Dale E. Van Sickle Raymond Vermeulen James P. Vokac and Stacey T. Baba Andrew Wang Raymond Chiu and Stephanie Wang Darsh T. Wasan David Wemmer Roger G. and Molly W. Williams Arthur M. Winer Gar Lok Woo Steven D. Young Robert Zahler

The Sather Gate Club and the College Council The Sather Gate Club members made commitments of $500-$999 this year and also belong to the College Council. Anonymous Carlo and Barbara Alesandrini Paul and Nicole Alivisatos Ward and Mary Alter Daniel and Shelley Arenson Frances Arnold Charles E. and Marianne Auerbach Burke and Carole Baker Michael L. Barry R. R. Breckenfeld Richard Brodzinsky Marilee Brooks Sheldon Cao and Vivian Wang* Robert E. Challey* Andrew Y. Cheng Andrew Cheung Gregory K. Chow J. P. and Nancy L. Clark Bernard and Akiko Comrie* Fred F. Coons Tucker Coughlen Peter Cukor Sheryl and Kenneth Dahl Robert and Rochelle Dreyfuss Carol Dunbar Arthur K. Dunlop Rudolph H. Dyck Jonathan and Caroline Earhart John G. Ekerdt Walton Ellis Dr. and Mrs. Victor Engleman Dr. Robert J. Farina Monte Faust Dr. and Mrs. Howard L. Fong Stanley W. Fong Reyes M. Fragoso Leif G. and Janet L. Fredin Philip R. Friedel Jennifer Fujii

* New donor(s) in 2006â&#x20AC;&#x201C;2007

benefits of John A. and Rosie J. Garibaldi Frank P. Gay Michael B. Gentzler Beth M. Grasel Tao Guo* Kenneth and Carol Hamilton* David R. Hansen Marlin D. Harmony Scott Hecker Mr. and Mrs. Allan P. Hess Duane A. Heyman Toshiaki Hino I. C. and Kimi Hisatsune William and Hoi-Ying Holman Nicholas W. Hornberger Erwin W. Hornung Donald Hou* John T. Hunt Mark Iiyama David R. and Karen W. Johnson Eileen M. Julian Alexis I. Kaznoff Gary and Patricia Kaiser Jack Kelly Sung-Hou and Rosalind Kim Yesook Kim Gene Kimura T. P. King Edward F. Kleinman Dr. Aaron D. Kossoy Jessica Lam* Jan and Maria Leeman Mark T. Lewellyn Mr. and Mrs. Kwang-Chi Liang Arnold A. Liebman Peter and Rachel Lipowicz Wendell and Bi-Lan Long* Mr. and Mrs. Henry H. Loo Ed Louie Michael and Jane MacDonald Mary M. Mader Prof. Bruce H. Mahan Estate Jon Maienschein and Lisa Cline Craig Markey Dr. Gerhard W. Matzen Robert C. McIntosh Robert K. Millar Lingfung Mok

private giving

THE FRANK DELFINO SCHOLARSHIP PRIZE and THE JOHN AND LOUISE RASMUSSEN SCHOLARSHIP Binh Nguyen is an undergraduate student studying chemical and nuclear engineering. The Delfino prize and the Rasmussen scholarship are helping him learn the skills he needs to help overcome the energy crisis and fight global warming. “As far as I can tell,” he says, “solar energy is not ready for wide application yet, and renewable fuels are still debatable. Of all the alternative energy sources, nuclear energy seems to be the most applicable to fighting climate change.” After graduation, Nguyen plans on working hard to make nuclear energy cleaner so that in the future the United States will become energy independent, and so, he adds, “My children can enjoy cleaner energy and a greener Earth without worrying about global warming.”

Binh Nguyen

Mike Moyer and Margaret Chu-Moyer Sean and Mary Mullen Dr. and Mrs. Louie Nady Prof. and Mrs. John S. Newman Richard Newman Allen Ng Douglas J. Ng Heino Nitsche and Martha Boccalini Nancy Norem David A. O’Brien Myongsook Oh Anthony O’Keefe Kiyoko T. Otsuki* Garry Iain George Parton John and Cheryl Petersen Jack M. Rademacher Janakiraman Ramachandran Gurdeep S. Ranhotra

Ronald Ratcliffe James R. Rice* June and Gene Roberts Fritz and Karen Schaefer Robert A. Scherrer John M. Seelig and Helen P. Zelt Seelig Mr. and Mrs. Arnold J. Seidule Dr. and Mrs. Stephen A. Shain Gerald Smolinsky David F. Starks Julie Stewart Neil C. Stipanich Jack D. Swanburg Dr. James S. Symanski Rex Tam Janet Tamada Sheil E. Taylro Jack Thomas John F. Thompson Don and Rosemary Tilley

Dr. Andrew Trapani Alain W. C. Tsang* Alexander and Laura Ur III* Ernesto Valdes-Krieg Dr. and Mrs. Emil J. Volcheck, Jr. Min-Chi Von Trentini Sheldon A. Weber Huinian Xiao and Bing Yuan Wei* Brandon T. Weldon* Marjorie and Greg Went Keith R. Westcott Ron and Lucy Wetzel Shara C. Williams* Phillip A. Wilmarth Katsumi and Elby Yamamoto

annual report ’06-’07

donors to the college The Carillon Club and the College Council The Carillon Club members made commitments of $250-$499 this year and are members of the College Council.

Anonymous (3) Phillip A. Armstrong Richard D. Aschenbrenner Karen Jernstedt and Jim Barkovich Craig P. Baskin Patrick Bengtsson and Erin Bydalek Stacey F. Bent and Bruce M. Clemens Carl M. Berke Prof. Jacob Bigeleisen Todd A. Blumenkopf Marie T. Borin, Ph.D. Richard W. Borry John and Claire Boursalian* Lawrence J. Bowerman David Burge James D. Burke C. Hackett Bushweller Roseanna M. Caldwell* Christopher and Michelle Chang* Michelle and Jeffrey Chang Shih-Ger (Ted) Chang Leland J. Chinn Jae Youn Cho* Dr. Ronald N. Clazie John W. Collette Peter S. Connell John E. Crider Dr. Matthew Croughan Drs. Cameron and Jean Dasch Christopher Dateo Timothy and Suzanne Devitt Ronald L. Dickenson Richard Dionne* Charles Do Michael J. Domeniconi Noelle M. Drugan

College of Chemistry, UC Berkeley

Lawrence H. Dubois Lois Durham Ernest Ehnisz, Jr. Judith Erb William H. Eustis Dr. Patricia L. Falcone and Family Stephen Falling Milton Finger Bruce A. Firestone, Ph.D.

Lara A. Gundel Paul H. Gusciora Tan-Ngoc Ha* SoonKap Hahn and Seung Hee Hahn Robert N. Hanson Dr. and Mrs. Frank Hernandez Frank Hershkowitz Robert G. Hickman

William Y. Ja David Y. Jackson Chao-Chung Jen* Jack Jew Samuel Sheun Woo Kam Brian D. Kelley Edward L. King Prof. Judith P. Klinman Deanne C. Krenz Camey Ku

Klara and David Dorsey present the Andrew Dorsey Award, commemorating their late son. Pictured left to right are professor Dirk Trauner, graduate student awardee Shelley Claridge, Klara Dorsey, graduate student awardee Kristine Nolin, Andrewâ&#x20AC;&#x2122;s sister, Sarah Dorsey, and David Dorsey.

Dr. George A. Fisk Tim Frederick D. S. (Pete) Fullerton Hubert Gasteiger Peter Gates Conrad E. Gleason David Godbey Joe Goddard* Abraham Goldhaar Vicki Grassian and Mark Young Ruth Grimes

Dr. William Higuchi Don Hildenbrand Dr. Jonathan Z. Ho Donna Hoel and Elvin L. Hoel* Richard W. and Patricia A. Hoff Richard Honnell Zhengjie Hu and Wendy Ng Judy C. Huang and Ken A. Nishimura Michael R. Hull

James T. Kuwada Emily and Lawrence Kwan* Howard Lacheen* Wilson Lam Sidney B. Lang Bart Larrenaga James W. Lewis Drs. Traci A. and Timothy A. Lewis James C. Lilley* Bernard J. Lilly, Jr. Mingjun Liu

* New donor(s) in 2006â&#x20AC;&#x201C;2007

S. Randolph Long Donald and Vicki Lucas Dr. Patricia D. Mackenzie Robert P. Mandal Enrique and Katalin Mannheim Newton W. McCready Karen and Steven McDonald Michael McKinney Kenneth E. Meeker Ron Meeker Richard L. Merson Drake and Jayne M. Michno Michael Milos David W. Moreland Arthur Morgan Paul Morrisroe Dr. John B. Nash Walter E. Nervik David R. Nethaway Felix G. Ngan and Lily M. Lee Camille and Jim Olufson Stephen ONeil Kent Opheim Robert J. Ouellette Harlan and Stanislava Overholt, Jr. Julie S. Oxner Keith and Suzanne Pang David B. Phillips Richard C. Pilger, Jr. Dr. J. Winston Porter Frank T. Prochaska Roland Quong Larry Ricker Patrick A. Rodgers Esther H. Rose Tom and Irene Rosko* Ola M. Saad* Harry N. and Jane L. Scheiber Dr. and Mrs. Francis J. Schmitz Erika Schneider, Ph.D. William J. Scott, M.D. Alan and Gail Searcy Frederic T. Selleck John L. Shafer Chris Lee and Scott Shaffer Jerry R. Shuper John A. Smegal

Randy Snurr Shinji and Masuko Soneda Ronald and Maureen Soulis Elaine Blatt Stoner Carolyn North and Herbert Strauss Frederick J. Strieter Chris Tagge Dr. and Mrs. Masato Tanabe Jeffrey Tane Ken Tokunaga Chi Wing Tsao David Uehling Tetsuo Uno* Renée van de Griend Jack M. Van Den Bogaerde Anthony C. Waiss, Jr. Cynthia and Dennis Wakita* Deane S. Walker Thomas A. Watters, M.D. Mark Wegner R. B. Weisenmiller, Ph.D. Rushan Wen and Qizhang Chao Mr. and Mrs. Anthony Wetherbee Ronald M. Wexler Dr. Richard J. Wilcox James T. Williams Mr. and Mrs. Arthur T. Wincek Paul Wollenzien Sachio Yamamoto Paul Zittel

The Campanile Club and the College Council The Campanile Club members made commitments of $100-$249 this year and belong to the College Council. Anonymous (5) Frank Jay Ackerman Dr. Raul E. Acosta Jeffrey and Tracy Adkins* Harry Alderson

Mr. and Mrs. Thomas L. Allen Gregory Andersen Allan Anderson Dr. Lawrence C. Andrews Robert A. and Nancy H. Antonoplis Dr. John D. Arenivar Morris and Stephanie Argyle Lucienne Ash Arnold C. Ashcraft, Jr. Kenton Atwood J. William Aubry Steven C. Avanzino Leif M. Backlund* Samuel D. Bader Reha M. Bafrali* Douglas J. Bamford Ian R. Bartky Keith F. Bates John Brennan and Jean Baum David and Pamela Baxter* David B. Beach, Ph.D. Brian and Lori Beaudoin* James R. Beck Ray G. Bedford Norman Peter and Eva Somer Belle David Berke* Patty and Bill Blanton Richard Boden Constantine G. Boojamra Jerome V. Boots Alex Boozenny* Mr. and Mrs. Marvin Brafman David E. Breen* Joanne Brenes* Robert J. Breuer Peter J. Brewer Harmon and Elizabeth Brown Leo D. Brown Edward Bruggemann Gina Buccellato Stacey B. T. Bui Joel D. Burley Frederick L. Burnett Gary P. Burns Kristina M. Burow* Charles N. Buser II* Elton and Miriam Cairns James L. Caley

Mark Camenzind Herbert Carlson Michael Carolan Joan Frisoli and Harry Cartland John and Elizabeth Cavanaugh* Chu-An Chang William and Joyce Chang Vivian Chapman* Gloria Cheng Rita L. Chia Rick Chin and Sandy Underwood C. Ching Rida Y. Chow* Zhi Liang and Lily Chu* Ellia Ciammaichella Shelley Claridge Dr. David L. Clark Kenneth E. Coates John B. Collins, Ph.D. Kaizar H. Colombowala F. Warren Colvin Michelle Coneybeare* Mary M. Conway Douglas H. Cortez Charles E. Coverdale Robert F. Curl David C. Darwin Pravin and Jyoti Dattani Kenneth E. De Bruin Paul and Camille Didas Denis and Donna Drapeau Howard Drossman Loretta and Michael Du Bois Patricia W. Durbin-Heavey Doug Edwards Tom and Donna Mae Ellis Alfredo and Estela Espinosa Dr. Mark R. Etzel Irving P. Everett, Jr. John Fabera Eric Fallon Heather Fan Paul L. Feldman Kenneth G. Felton Dwight A. Fine Jay and Leslie Fishman Warren W. Flack Bruce M. Foreman

annual report ’06-’07

The Campanile Club and the College Council, continued

Paul Forney* Matthew K. Fountain Mary M. Fox Elizabeth Green Francois Milton S. Frank Loyd Frashier Charles and Margaret Frazier Aihua Fu Sabrina S. Fu and Philip J. Rous Kent Fung Ethan C. Galloway Dr. Donald E. Garrett Don and Donelle Gartner Ted C. Germroth J. Daniel Gezelter* Randall F. Gibson* Jack and Judy Gilmore Mike Goerger Avery Goldstein Gary M. Goncher Judson E. Goodrich Michael and Crystal Goodwin Alex Goretsky* Samuel L. Graham Harold and Margaret Granquist* Ronald W. Grant Susan Graul Joseph M. Greendorfer Laura Greenfield Charles E. “Ched” Grimshaw Robert and Hannah Grossman David Guidry Robert R. Gunther Robert W. Hand Curtis and Marilee Handley* Dr. and Mrs. John Harder George L. Hardgrove, Jr. Mr. and Mrs. J. Ronald Hargreaves B. Neal Harman Ian Harris David J. Hart Steven L. Hartford Mark A. Hartney

College of Chemistry, UC Berkeley

Graduate student Stavroula Hatzios mentors undergraduate Zsofia Botyanski in the Bertozzi laboratory. Undergraduate research is funded in part through private gifts.

Thomas Harvey Michal and Timothy Hawk Auda “Kay” Hays Susan Heinemann Tana Woodward Henderson Robert W. Hermsen Louis and Nellie Herrington William T. Hicks Orville and Florence Hiepler* Charles Higdon Eric Hintsa Jason Ho Nick Ho* James D. Hoefelmeyer* Bob and Lisa Holden

Stephen M. Holton Jin-Lon and Mei-Shel Hon* Chris Hovde Richard, Ann and Beverly Hovsepian Limin Hsueh Chung-Hwa Huang LiXuan Huang Dr. James L. Hyde Mary Lee Hyde Jolene M. Ignowski* Larry and Nadine Isaacs* Michael K. Ishii Adrienne Iwata Thomas and Mottlene Jarvis

Mila and José Javier John A. Jensvold Audrey Johnson Kyonggeun Johnson Russell D. Johnson, Jr. Louis and Grace Jones Patricia A. Jones Russell L. and Patricia W. Jones Dr. Shee Lup Jung Margaret Noble Kain, Ph.D. James S. Kane Chia Chen Chu Kang Michael Karim* Jerome V. V. Kasper* Jack A. Keenan William H. Keesom Eric R. Keim Esayas Kelkile* Carl S. Kellner Ellen Kick John S. Killian Andrew Kindler Baldwin A. King Uwe Kirbach* Kathryn Barr Kirtley James A. Klein William and Elizabeth Klemperer James Klohr Peter Knappe Roland Koestner Trudy Kong Tony Kovscek and Rebecca Taylor Mark H. Krackov* Shailaja Krishnamurthy Shou S. Kwong Cam-Mi La* John R. Lai Stephen M. Lambert Joseph R. Landolph, Jr. Lee H. Latimer Philip Lau and Quina Chang Silvanus S. Lau Christina J. Lee* Chun-Yue Lee Fourmun Lee* Mei Kim Carol Lee

* New donor(s) in 2006–2007

donors to the college Wei-Luo Lee* Wen Chin Lee Norman and Yvonne Lee Alice Lee-Dutra* Allen and Phyllis Lefohn Theodore J. Leitereg* Prof. and Mrs. William A. Lester, Jr. Cissy Leung Tak and Maggie Leung Alan Levy A. Lew John D. Leyba Dr. William G. Light James Lim Manfred Lindner Gary Lipscomb II Benjamin T. Liu* Pamela Liu* David and Judith Lloyd Wai Leng Loh* Harold R. Lohr Larry Loomis-Price Ying Y. Lu* Charles Ludvik Ka Lum Xuan Hung and Van Gia Ly Bjorn Christian Lyche Tom Mac Phee Raymond W. Mah* Christopher A. Maines Chander Malhotra* Emma and Stephen Mallon Doug Mandel Nolan Mangelson David and Kimchi Mao* Nicolas and Mari Carmen Mariscal* J. Hodge Markgraf David and Debra Marlin Linda N. Marquez David W. M. Marr W. Paul Martin Carol Masinter Toby (Horwitz) Massman* Alexander Mastroianni* Paul and Julia Mathews Kevin McAlea Con and Mary McCormick

Dr. William R. McDonell James W. McFarland Robert McKoon Kevin L. McLaren Haig and Armine Mekhdjian* Jeanlynn and Arjen Mets Charles and Diane Meyer J. Hoyt Meyer* Richard Michelman and Karen Meyer Donald G. Miller Steven Miller William G. Miller Prof. and Mrs. William H. Miller William M. Miller David Mobley David R. Monroe Terry Moody Lorna Morgan* Barbara and Dennis Morrell Lester R. Morss Earl M. Mortensen Bob and Becky Mortlock Jim Muirhead Thomas F. Murphy William Murray Nate Neale Harry (Tom) Nelson Eddie and Tibbie Ng Yu Sim Ng John J. O’Brien John P. O’Connell Nicholas L. Ohler* Jon and Susan Okada Miles S. Okino Adam S. Olgin Jackie Orbon Kenneth M. Otteson Semik and Laurie Oungoulian* James Oziomek Roberto Pabalan Spyridon Papadakis Dr. Rudolph Pariser Je Myeong and Sun Ok Park* John H. Parker John E. Parmeter Ara G. Paul*

Charles W. Paul Dehua Pei* Winfield B. Perry Dr. Eric C. Peters Leonidas Petrakis Paul A. Petruzzelli Matthew Plunkett Michael and Cathy Pollak* Max Y. Pong Madhava Prasad* Kristala Jones Prather Max Pray Elisabeth M. Price Susan Puglia Nicholas Pugliano and Family Abdur R. and Roksana Quazi* Peter D. Quinn David T. Rabb Tom and Betty Ransohoff Manfred G. Reinecke Richard A. Reinhardt Janice Reutt-Robey John Dischinger and Mindy Rex* Jed L. Richardson Keith Rickert Alice Rico Gregory A. Roberts* Gary L. Robison* Mark Roebuck Dr. and Mrs. C. B. Roland Gerry Rollefson Mark E. Rosen Robert and Sandra Rosenthal* Barney Rubin David S. Rumschitzki Steven Russek Philip P. Russell Edna Kazuko Sakai Norma I. Santiago* Nick R. Schott William and Virginia Schultz William B. Schwabacher Stephen E. Schwartz Dr. Gretchen Schwenzer Richard Searle George V. Shalimoff Anita J. Shaw

Ginton Shelef Pi-teh Shen Mr. and Mrs. Clayton C. Shepherd* Albert E. Sherwood Martin D. Shetlar James S. Shirk Mary F. Singleton Eric R. Sirkin Arthur C. Smith Dr. John E. Sohn Kimania A. Stancil and Nicole S. Love* Bob Steininger David Stern William and Rose Stock Nancy and Mark Stoyer Pieter Stroeve Joseph and Dorothy Swintosky* F.M.G. Tablas* Tellers Family William Templeton* Joyce and Peter Teng Klaus H. Theopold Paul and Haviland Thompson L. Karl J. Tong* Tracy Tram Michael Trenary Jennifer A. Tripp Robert L. Tromp William C. L. and Miranda Tsang Noel H. Turner John P. Unik Ellen and Robert Van Spyk* Sue and Bob Vandenbosch Nikhil and Manisha Varaiya* David L. Wagger Diane Wakeham* Jennifer S. Wakita Timothy P. Walker Francis Wang Gloria Wang Lisa Wang Robert Waterhouse David Watt Robert F. Weimer Dwight D. Weller

annual report ’06-’07

donors to the college The Campanile Club and the College Council, continued

William C. Wernau Richard A. Whitbeck* Gary P. Wiesehahn Jay Wiesenfeld* Hans Wijffels Richard Q. Williams Earl Wilson Dr. and Mrs. Curt Wittig Chung M. Wong* Connie Wong Eric K. Wong Jack Wong Patrick M. Wong* Sharon M. Wong Barbara Wood Kevin D. and Virginia M. Woodburn* Ronald Wright Priscilla L. Yang and Nathanael S. Gray Weidong and Diane Yang* Zhen-Yu Yang Grace Yap Donald G. Young Raymond K. Yu Qing S. Yuan Qingqi Yue and Huaixia Yao Federico Zaraga Frederick Zee C. A. Zimmerman Robert D. Zimmerman John Zinn Rebecca Zuckerman Ronald Zuckermann*

The Honor Roll The Honor Roll acknowledges individuals who have contributed up to $99 to the college. Anonymous (2) Vladislav I. Afanasevich* Dr. Habib Amin Ray Amsinger

College of Chemistry, UC Berkeley

Lawrence and Phyllis Anderson Kevin Austin Robert P. Bacher Bruce and Holly Bader Edward M. Barrish George H. Batchelder Carolyn C. and Russell H. Batt* L. J. Beaufait Marvin and Eleanor Beil* Dean R. Bender Rick Bertram Harald and Carol Biedermann Leland F. Blinman Linda Blum Peter G. Boisvert Jacklyn T. Bort Rebecca E. Brafman Steven Bromberg* Edward M. Brooks* Mark A. Burlingame* Helen Cameron* Jonathan O. Carlson John W. Carroz Ada Woo and Joe Carson Arnold and Tina Cavalli Pak Ping Chan Rossana Chan* Chellappah and Rada Chanmugathas Joan Chao Mr. and Mrs. Thomas J. C. Chew Ara Chutjian David Clay Dick T. Co Jeffrey M. and Kerry L. Cogen James L. Cole* Paul A. Cornelius Virginia W. Cornish George J. and Thetis G. Crits Ulysses S. Curry* Geoffrey and Gail Dafforn Jacob M. Davis George S. Detre Faye F. Detsky-Weil and David H. Weil* Stephen G. DiMagno James R. Douglass Ronald P. Drucker

Michelle M. Eastlack* John W. and Marlene Jensen Eastman David Eichhorn Mark Elfield and Kristin Homme* Alan S. Emanuel Chris M. Erickson Larisa Falvey Maria Fardis Peter Fedkiw* Jere D. and Theresa D. Fellmann Neil Fromer* John Gavenonis Willis and Kathryn Gelston* David Glueck Cynthia Gong* Andrew Goodwin* Michael L. Greenfield Marjory and George Greenwald Jondi Gumz Fanqing Guo* Neil S. Hanabusa Michael R. Harper* Virginia-Jane Harris Jeanne and Robert Haushalter Thomas and Jacqueline Hayes* Hansel Ho* Lisa M. Hochrein David Holtz Virginia H. Homme* Horace and Lois Hopkins Louisa Mae A. Horton Wenyen Hsu R. F. Humphreys Ronald Jensen Fan Jiang and Jinfang Liao* Franklin Jin Andreas V. Kadavanich Nandakumar and Lekha Kalathil* Thomas Ross Kelly* Indu Kheterpal Jason C. King* Sherman and Ming Ko* Selene Koo Dr. L. N. Kramer

Georgina Garbutt Kratzer John and Hanna Krebs Cindy Krieger Romesh Kumar Samuel Kurita and Mary A. Long* Yatping Kwan Martin and Nailin Lee* Colin W. Lees Suzanne Kam-Cee Leung Elaina Lin David Lindsay Steven and Esther Lopez* Richard Luke Richard MacPhail Tom Maimone Norbert and Helmi Mason Helen and John Matthews* James Brozek and Linda McCrackin Barry and Donna McElmurry T. Andrew Mobley* Rob Moore Barry T. Murphey Norman T. Nelson Caroline Nguyen William C. Orr Fakhruddin and Fatema Palida* James and Donna Pappas* Christine K. Payne* George and Charlotte Peck* Dragutin Peric Jaan Pesti Robert N. Pike Jason Ploeger Jan Polissar Carol Ann and Steven Popeney Steven Pratt Jesse Qi and Jimei Tian Christina Lee Quigley Ronald A. Reimer Gerald L. and Maureen J. Ritter Stephanie Robertson* Mr. and Mrs. Robert K. Roderick* Michael and Kay Rosen

* New donor(s) in 2006â&#x20AC;&#x201C;2007

Charles J. Russell* Joel W. Russell Wayne E. Sackett* Arutyun and Isabella Saryan Alexander Sassi Terry Trosper Schaeffer Joshua A. Schrier*

Dr. Paul Suslov and Family* Alan Tam* Vazken Tashinian Sundiep K. Tehara George L. Tong Sandor and Magdolna Trajmar

Nicolas D. Winter* Margaret A. Wong Adam Woolley David T. Wu Terry T. Yamada Liub-Chii Yang Chen Laura Yee

Alumni and friends at the Dean’s Dinner spanned several eras. Pictured, left to right, are Nancy Henderson, Edmund Chambers (B.A. ’39, Chem), Milton Ritchie (B.S. ’51, Chem) and David Lieu (B.S. ’75, Chem).

Alan Sentman* George S. Sheppard Kenneth and Myrtle Kit Shimota* James N. Shoolery* Todd P. Silverstein Sara and Bakthan Singaram Joseph Sonnenberg Carla St. Laurent, M.D. Susan Stanton Elise C. Stone Gerald E. Streit James and Patricia Stubbert Warren C. Stueben John P. Sullivan

Victor and Susan Tsai Ricardo Unikel Mathias Van Thiel Paul Verderber Michael Verti David J. Vieira Mary Conway Vondrak Adam Z. Weber* Karen M. Webster* John B. Wheeler, Jr. Ralph E. White David Whitmore Mikel Wiebenson* John J. M. Wiener* Hewitt G. Wight Thomas Winfield*

Joel E. Yeo* Adam Youngman* John L. Zelinsky* Sally A. Zengel* Shengbo Zhu and Baoqi Ding

Current and Former Faculty and Staff Donors Carlo and Barbara Alesandrini Keith and Elaine Alexander Paul and Nicole Alivisatos William and Inez Benjamin

Robert and Wendy Bergman Bud Blue Elton and Miriam Cairns Helen Cameron* Joseph and Susan Cerny Christopher and Michelle Chang* Jamie and Jennifer Doudna Cate* Elaine and Arnold Grossberg Charles B. Harris Clayton Heathcock and Cheri Hadley Erwin W. Hornung Kiyoshi and Irene Katsumoto Sung-Hou and Rosalind Kim Prof. and Mrs. C. Judson King Prof. Judith P. Klinman Prof. and Mrs. William A. Lester, Jr. Scott and Annette Lynn Prof. Bruce H. Mahan Estate J. Hodge Markgraf Prof. Samuel and Mrs. Lydia Markowitz Richard and JoAnne Mathies Prof. and Mrs. William H. Miller Arthur Morgan Prof. and Mrs. John S. Newman Heino Nitsche and Martha Boccalini Camille and Jim Olufson Norman and Paula Phillips Prof. and Mrs. John M. Prausnitz John Dischinger and Mindy Rex* Richard Saykally and Chris Read Fritz and Karen Schaefer Harry N. and Jane L. Scheiber Judith and Gabor Somorjai Carolyn North and Herbert Strauss Vazken Tashinian David and Lieselotte Templeton Don and Rosemary Tilley David Wemmer

annual report ’06-’07

donors to the college Parent Donors

Jeffrey and Tracy Adkins* Richard D. Aschenbrenner Leif M. Backlund* David and Pamela Baxter* Brian and Lori Beaudoin* Linda Blum John and Claire Boursalian* Mr. and Mrs. Marvin Brafman Joanne Brenes* Roseanna M. Caldwell* Sheldon Cao and Vivian Wang* John and Elizabeth Cavanaugh* Pak Ping Chan William and Joyce Chang Chellappah and Rada Chanmugathas Vivian Chapman* Tan-Jen and Li-Fong Chen Jae Youn Cho* Zhi Liang and Lily Chu* Bernard and Akiko Comrie* Michelle Coneybeare* Faye F. Detsky-Weil and David H. Weil* Paul and Camille Didas Charles Do Loretta and Michael Du Bois Carol Dunbar Tom and Donna Mae Ellis Alfredo and Estela Espinosa Monte Faust Jay and Leslie Fishman Mary M. Fox Charles and Margaret Frazier Don and Donelle Gartner Willis and Kathryn Gelston* Michael and Crystal Goodwin Marjory and George Greenwald Ruth Grimes Robert and Hannah Grossman Ronald Grzywinski* Jondi Gumz SoonKap Hahn and Seung Hee Hahn Kenneth and Carol Hamilton* Curtis and Marilee Handley*

College of Chemistry, UC Berkeley

Jeanne and Robert Haushalter Michal and Timothy Hawk Dr. and Mrs. Frank Hernandez Mr. and Mrs. Allan P. Hess Nick Ho* William and Hoi-Ying Holman Jin-Lon and Mei-Shel Hon* Irma Hrycyk Wenyen Hsu Chung-Hwa Huang Larry and Nadine Isaacs* Bala and Kumari Iyer* Mila and Jose Javier Chao-Chung Jen* Fan Jiang and Jinfang Liao* Louis and Grace Jones Eileen M. Julian Margaret Noble Kain, Ph.D. Nandakumar and Lekha Kalathil* Ronald and Coleen Kino* Sherman and Ming Ko* Engr. Joseph L. and Dr. Helen C. Koo LaRoc and Linda Kovar Shailaja Krishnamurthy Samuel Kurita and Mary A. Long* Emily and Lawrence Kwan* Cam-Mi La* Philip Lau and Quina Chang Wen Chin Lee Norman and Yvonne Lee Tak and Maggie Leung Mr. and Mrs. Kwang-Chi Liang Liming M. Linger Pamela Liu* Wendell and Bi-Lan Long* Steven and Esther Lopez* Richard Luke Xuan Hung and Van Gia Ly Chander Malhotra* Emma and Stephen Mallon David and Kimchi Mao* David and Debra Marlin Carol Masinter Paul and Julia Mathews Helen and John Matthews* Con and Mary McCormick

James Brozek and Linda McCrackin Larry and Debbie Meisner Haig and Armine Mekhdjian* Eddie and Tibbie Ng Jon and Susan Okada Semik and Laurie Oungoulian* Harlan and Stanislava Overholt, Jr. Fakhruddin and Fatema Palida* Keith and Suzanne Pang Je Myeong and Sun Ok Park* George and Charlotte Peck* Michael and Cathy Pollak* Carol Ann and Steven Popeney Jesse Qi and Jimei Tian Abdur R. and Roksana Quazi* Janakiraman Ramachandran Mr. and Mrs. Robert K. Roderick* Dr. and Mrs. C. B. Roland Tom and Irene Rosko* Marsha Sable Norma I. Santiago* Arutyun and Isabella Saryan John M. Seelig and Helen P. Zelt Seelig Sara and Bakthan Singaram Shinji and Masuko Soneda James and Patricia Stubbert Joyce and Peter Teng Alexander and Laura Ur III* Ellen and Robert Van Spyk* Nikhil and Manisha Varaiya* Cynthia and Dennis Wakita* Jennifer S. Wakita Huinian Xiao and Bing Yuan Wei* Rushan Wen and Qizhang Chao Mr. and Mrs. Anthony Wetherbee Mr. and Mrs. Arthur T. Wincek Thomas Winfield* Connie Wong Kevin D. and Virginia M. Woodburn* Weidong and Diane Yang*

Qingqi Yue and Huaixia Yao Sally A. Zengel* Shengbo Zhu and Baoqi Ding

G. N. Lewis Era, Classes through 1945 These donors represent a participation rate of 14.1 percent for the G. N. Lewis Era. Mr. and Mrs. Thomas L. Allen Ward and Mary Alter Dr. and Mrs. David Altman Kenton Atwood J. William Aubry Charles E. and Marianne Auerbach L. J. Beaufait Prof. Jacob Bigeleisen Dr. Tom A. Bither, Jr., and Mrs. Margaret V. Bither Leland F. Blinman Bud Blue Jacklyn T. Bort R. R. Breckenfeld Robert J. Breuer James L. Caley William H. Calkins Herbert Carlson Edmund Chambers Fred F. Coons Dr. and Mrs. Gus D. Dorough, Jr. Arthur K. Dunlop William H. Eustis Matthew K. Fountain Milton S. Frank John A. and Rosie J. Garibaldi Dr. and Mrs. Theodore H. Geballe Edward D. Goldberg Abraham Goldhaar G. Douglas and Regina Gould Vic and Faye Gunther Virginia-Jane Harris

* New donor(s) in 2006â&#x20AC;&#x201C;2007

benefits of

private giving

THE LI FELLOWSHIP in Memory of Choh Hao Li Massoud Motamed was born and raised in Texas and attended Southern Methodist University in Dallas. He discovered chemistry while at SMU. He is now settled in the Bay Area, and he is a graduate student and a member of the Richmond Sarpong group. He works on the synthesis of natural products and pharmaceutically important small molecules, especially nitrogen-containing heterocycles. “It is really exciting to win the Li award as it is a great financial benefit to our lab,” he says. Choh Hao Li (Ph.D. ’38, Chem) directed the Hormone Research Laboratory at Berkeley from 1950-67 and at UCSF from 1967-83.

Massoud Motamed

Dr. James L. Hyde Dr. Shee Lup Jung Jack A. Keenan Edward L. King Henry F. Koopmann Prof. Daniel E. Koshland, Jr. Georgina Garbutt Kratzer Newton W. McCready Arthur Morgan T. W. Newton Dr. Rudolph Pariser Paul A. Petruzzelli Robert N. Pike Jonathan S. Powell Jack and Daisy Yep Quan Jack M. Rademacher Eugene B. Reid Richard A. Reinhardt June and Gene Roberts J. A. Sanford

Mr. and Mrs. John R. Skinner David and Lieselotte Templeton Paul and Haviland Thompson L. Karl J. Tong* John B. Wheeler, Jr. Rita Wieland Earl Wilson C. A. Zimmerman

Cupola Era, Classes of 1946–1963 These donors represent a participation rate of 12.9 percent for the Cupola Era. Frank Jay Ackerman*

Profs. Juana V. and Andreas Acrivos Harry Alderson Ward and Mary Alter Allan Anderson Lawrence and Phyllis Anderson Dr. Lawrence C. Andrews Myron and Barbara Andrews Lucienne Ash Ian R. Bartky David Bass George H. Batchelder Keith F. Bates James R. Beck Edwin D. Becker Ray G. Bedford John H. Birely M. Robert Blum Jerome V. Boots Alex Boozenny*

R. R. Breckenfeld David E. Breen* Edward M. Brooks* Harmon and Elizabeth Brown David Burge John B. Bush, Jr. Elton and Miriam Cairns William H. Calkins Robert J. Carr John W. Carroz Joseph and Susan Cerny David C. K. Chan Sunney I. Chan Mr. and Mrs. Thomas J. C. Chew Leland J. Chinn T. Z. and Irmgard Chu Dr. Ronald N. Clazie Ronald L. Clendenen Warren E. Clifford

annual report ’06-’07

donors to the college Cupola Era donors, continued

John W. Collette Robert S. Crowder Robert F. Curl William A. Daniels Pravin and Jyoti Dattani Frank and Janice Delfino Ronald L. Dickenson Walter and Eleanor Dong Dr. and Mrs. Gus D. Dorough, Jr. Clelland R. Downs David and Wena Dows Arthur K. Dunlop Patricia W. Durbin-Heavey Lois Durham Rudolph H. Dyck John W. and Marlene Jensen Eastman Helen M. Elliott Walton Ellis Alan S. Emanuel William H. Eustis Irving P. Everett, Jr. John Fabera Dwight A. Fine Milton Finger Bruce M. Foreman Loyd Frashier Ethan C. Galloway Dr. Donald E. Garrett Peter Gates Frank P. Gay Dr. and Mrs. Theodore H. Geballe William and Janet Gerhardt Jack and Judy Gilmore Conrad E. Gleason Joe Goddard* Mr. and Mrs. Wataru Goishi Judson E. Goodrich Harold and Margaret Granquist* Ronald W. Grant Joseph M. Greendorfer George L. Hardgrove, Jr. Mr. and Mrs. J. Ronald Hargreaves B. Neal Harman

College of Chemistry, UC Berkeley

Marlin D. Harmony John F. Heil Robert W. Hermsen Louis and Nellie Herrington Robert G. Hickman William T. Hicks Dr. William Higuchi Don Hildenbrand I. C. and Kimi Hisatsune Richard W. and Patricia A. Hoff Richard Honnell

James S. Kane David G. Karraker Stanley Kelly John S. Killian T. P. King Mr. and Mrs. Fred Kirby William and Elizabeth Klemperer James Klohr Mark H. Krackov* James T. Kuwada Shou S. Kwong

Rita Wieland (B.S. ’46, Chem) and Morton McDonald enjoy the Dean’s Dinner.

Horace and Lois Hopkins Erwin W. Hornung Richard W. Hyman Robert and Gene Iwamoto William Y. Ja Franklin Jin Russell D. Johnson, Jr. John Jost, Jr. Dr. Max J. Kalm Samuel Kam Sheun Woo

John R. Lai Sidney B. Lang Martin and Nailin Lee* Virginia and Frank Lew David A. Lightner James Lim Manfred Lindner Robert and June Lindquist Harold R. Lohr Dick and Myra Lynch

Raymond W. Mah* Arturo Maimoni Robert P. Mandal W. Paul Martin Dr. William R. McDonell James W. McFarland Kenneth E. Meeker Richard L. Merson Charles and Diane Meyer Robert K. Millar Donald G. Miller Arthur Morgan Earl M. Mortensen Merrill A. Muhs Barry T. Murphey William Murray Albert Narath Charles and Clinton Nash Harry (Tom) Nelson Walter E. Nervik David R. Nethaway Prof. and Mrs. John S. Newman T. W. Newton William C. Orr Robert J. Ouellette Chin-Tzu Peng Leonidas Petrakis Dr. Donald D. Phillips Llad Phillips Richard C. Pilger, Jr. Jan Polissar Dr. J. Winston Porter Madhava Prasad* Jack and Daisy Yep Quan Roland Quong Manfred G. Reinecke Richard A. Reinhardt Lanny Replogle Gregor Riesser Milton H. Ritchie Gary L. Robison* Gerry Rollefson Ferenc E. Rosztoczy Barney Rubin Klaus and Mary Ann Saegebarth Elmer E. Schallenberg Robert A. Scherrer

* New donor(s) in 2006–2007

Dr. and Mrs. Francis J. Schmitz William B. Schwabacher Alan and Gail Searcy Richard Searle Mr. and Mrs. Arnold J. Seidule Manesh and Margarita Shah Dr. and Mrs. Stephen A. Shain George V. Shalimoff James N. Shoolery* Hugh C. Silcox Mary F. Singleton Arthur C. Smith Gerald Smolinsky Judith and Gabor Somorjai Joseph Sonnenberg Ronald and Maureen Soulis Dr. Charles E. Stehr Julie Stewart Frederick J. Strieter Jack D. Swanburg Therese W. Sze* Dr. and Mrs. Masato Tanabe Jerome H. and Selma E. Targovnik Vazken Tashinian Richard M. Teeter David and Lieselotte Templeton William Templeton* George L. Tong Sandor and Magdolna Trajmar Robert L. Tromp Noel H. Turner John P. Unik Dale E. Van Sickle Mathias Van Thiel Sue and Bob Vandenbosch Dr. and Mrs. Emil J. Volcheck, Jr. Anthony C. Waiss, Jr. Sheldon A. Weber Richard A. Whitbeck* Rita Wieland Hewitt G. Wight Gar Lok Woo Sachio Yamamoto John Zinn

Free Radicals, Classes of 1964–1979 These donors represent a participation rate of 10.2 percent for the Free Radicals Era. Dr. Raul E. Acosta Carlo and Barbara Alesandrini Dr. Habib Amin Ray Amsinger Gregory Andersen Lester Andrews Arnold C. Ashcraft, Jr. Steven C. Avanzino Robert P. Bacher Bruce and Holly Bader Samuel D. Bader Burke and Carole Baker Ron and Sue Banducci Karen Jernstedt and Jim Barkovich Edward M. Barrish Michael L. Barry Craig P. Baskin Carolyn C. and Russell H. Batt* Richard Behrens Dean R. Bender Patrick Bengtsson and Erin Bydalek Carl M. Berke Rick Bertram Patty and Bill Blanton Richard Boden Peter G. Boisvert Lawrence J. Bowerman Robert G. Brinkley Leo D. Brown James D. Burke Frederick L. Burnett Gary P. Burns Charles Buse C. Hackett Bushweller Jonathan O. Carlson Robert E. Challey* Uma and Kumar Chandrasekaran

Shih-Ger (Ted) Chang Cecil C. Chappelow Nirmal and Ellen L. Chatterjee Andrew Cheung Rita L. Chia Gregory K. Chow Ara Chutjian J. P. and Nancy L. Clark Robin D. Clark and Mary Mackiernan David Clay Dr. Ronald N. Clazie Kenneth E. Coates John B. Collins, Ph.D. Kaizar H. Colombowala F. Warren Colvin Peter S. Connell Mary M. Conway Douglas H. Cortez Tucker Coughlen Charles E. Coverdale John E. Crider Peter Cukor Geoffrey and Gail Dafforn Drs. Cameron and Jean Dasch Kenneth E. De Bruin Tom and Marty De Jonghe Thomas and Cynthia Delfino George S. Detre Timothy and Suzanne Devitt Drs. Thomas J. Dietsche and Laura J. Dietsche Michael J. Domeniconi James R. Douglass Dean C. Draemel Robert and Rochelle Dreyfuss Ronald P. Drucker Jonathan and Caroline Earhart Dr. Victor H. Edwards Ernest Ehnisz, Jr. Dr. Julianne Elward-Berry Gail G. Engerholm Dr. and Mrs. Victor Engleman Judith Erb Chris M. Erickson Virginia and Larry Faith Stephen Falling Steven and Terri Fantazia Dr. Robert J. Farina

Peter Fedkiw* Jere D. and Theresa D. Fellmann Kenneth G. Felton Bruce A. Firestone, Ph.D. Dr. George A. Fisk Michael and Mary Flaugh Dr. and Mrs. Howard L. Fong Paul Forney* Philip R. Friedel D. S. (Pete) Fullerton Kai-Ye Fung Shun C. Fung Drs. David S. Gee and Caryn C. Lum Ted C. Germroth Man K. Go Mike Goerger Charles E. “Ched” Grimshaw Lara A. Gundel Robert R. Gunther Robert W. Hand David R. Hansen Robert N. Hanson Dr. and Mrs. John Harder Ian Harris David J. Hart Steven L. Hartford Thomas Harvey H. Ross Hawkins Auda “Kay” Hays John F. Heil Jessie Herr Duane A. Heyman Robert G. Hickman Hansel Ho* Donna Hoel and Elvin L. Hoel* Bob and Lisa Holden Stephen M. Holton David Holtz Nicholas W. Hornberger Limin Hsueh Victor W. Huang* R. F. Humphreys John T. Hunt Mark Iiyama Michael K. Ishii Adrienne Iwata

annual report ’06-’07

Free Radicals Era donors, continued

Thomas and Mottlene Jarvis Jack Jew David R. and Karen W. Johnson Kyonggeun Johnson Russell L. and Patricia W. Jones Gary and Patricia Kaiser Dr. and Mrs. Andrew Kaldor Jerome V. V. Kasper* Kiyoshi and Irene Katsumoto Michael C. Kavanaugh and Carol R. James William H. Keesom Jack Kelly Thomas Ross Kelly* Mr. and Mrs. David E. Kepler II Hyunyong Kim Gene Kimura Baldwin A. King Kathryn Barr Kirtley William A. Kleschick Trudy Kong Dr. Aaron D. Kossoy Dr. L. N. Kramer Camey Ku Romesh Kumar Yatping Kwan Wilson Lam Joseph R. Landolph, Jr. Lee H. Latimer Silvanus S. Lau Polam and Marcia Lee Colin W. Lees Allen and Phyllis Lefohn Theodore J. Leitereg* Alan Levy A. Lew Mark T. Lewellyn James W. Lewis Arnold A. Liebman Dr. William G. Light Bernard J. Lilly, Jr. David Lindsay David and Judith Lloyd Mr. and Mrs. Henry H. Loo Donald and Vicki Lucas Charles Ludvik

College of Chemistry, UC Berkeley

benefits of

private giving

THE KOO LIU SIOK-HAN AWARD and THE STANLEY G. THOMPSON MEMORIAL AWARD Paul Hernandez grew up in Chula Vista, south of San Diego. He had no plans to study chemistry at Berkeley until he took introductory chemistry and was hooked by the passion of his teachers. Hernandez is working as an undergraduate in the research group of Dirk Trauner. The Trauner group focuses on the total synthesis of complex natural products and rationally designed molecular probes and their application to biological problems, especially in neuroscience. Hernandez was a co-author on a paper about using a synthetic technique called cycloaddition to help synthesize a class of chemicals first discovered in Caribbean corals. “These awards have eased my financial worries,” says Hernandez, “and have allowed me to focus on my studies and research year ’round.”

Paul Hernandez

Bjorn Christian Lyche Nolan Mangelson Craig Markey Gary and Irene Masada Thomas A. Massaro, M.D. Barry and Donna McElmurry Robert McKoon Thomas J. Meyers Drake and Jayne M. Michno Dr. Michael J. Miller Steven Miller William G. Miller Luisa T. Molina David R. Monroe

Tim Montgomery Terry Moody Dr. and Mrs. Joon S. Moon Barbara and Dennis Morrell Paul Morrisroe Lester R. Morss Jim Muirhead Curt Munson and Hazel Olbrich Thomas F. Murphy Dr. and Mrs. Louie Nady Dr. John B. Nash Norman T. Nelson Richard Newman

Joan Friedman Newmark and Richard Newmark Allen Ng Douglas J. Ng Yu Sim Ng Felix G. Ngan and Lily M. Lee Nancy Norem Carlos and Patricia Nuila John P. O’Connell Myongsook Oh Stephen ONeil Kent Opheim Kenneth M. Otteson James Oziomek

* New donor(s) in 2006–2007

donors to the college Rodney and Jeanne Panos John H. Parker William R. Parrish Ara G. Paul* Dragutin Peric Winfield B. Perry David B. Phillips Max Y. Pong Dr. J. Winston Porter Steven Pratt Elisabeth M. Price Frank T. Prochaska David T. Rabb Ronald Ratcliffe Ronald A. Reimer Larry Ricker Gerald L. and Maureen J. Ritter Scott Rocklage Esther H. Rose Joel W. Russell Nick R. Schott William and Virginia Schultz Gary P. Schwartz Stephen E. Schwartz Dr. Gretchen Schwenzer Drs. Steven Sciamanna and Sandy J. Roadcap William J. Scott, M.D. John L. Shafer Ginton Shelef Pi-teh Shen Albert E. Sherwood Martin D. Shetlar James S. Shirk Jerry R. Shuper Karen and Scott Sibbett Ronald E. Silva Sher G. Singh Clinton D. and Sharon Snyder Thomas M. Stachelek* Bruce E. and Susan J. Stangeland Susan Stanton David F. Starks Bob Steininger Donna R. Sterling Neil C. Stipanich Elaine Blatt Stoner Gerald E. Streit

Pieter Stroeve F.M.G. Tablas* Kong-Heong Tan Anne Friend Thacher Jack Thomas Ken Tokunaga Curtis Tong Dr. J. A. Trainham and Dr. L. D. Waters Michael Trenary Alain W. C. Tsang* Chi Wing Tsao Constantine Tsonopoulos George K. and Stephanie D. Tyson Ernesto Valdes-Krieg Jack M. Van Den Bogaerde David J. Vieira James P. Vokac and Stacey T. Baba Mary Conway Vondrak Andrew Wang Francis Wang Darsh T. Wasan Robert Waterhouse David Watt Thomas A. Watters, M.D. Mark Wegner Robert F. Weimer R. B. Weisenmiller, Ph.D. Willard M. Welch Dwight D. Weller David Wemmer William C. Wernau Alex Wernberg Ron and Lucy Wetzel Ralph E. White Gary P. Wiesehahn Jay Wiesenfeld* Hans Wijffels Richard Q. Williams Roger G. and Molly W. Williams Arthur M. Winer Paul Wollenzien Margaret A. Wong Ronald Wright Terry T. Yamada Katsumi and Elby Yamamoto Donald G. Young

Raymond K. Yu Robert Zahler Federico Zaraga Frederick Zee Robert D. Zimmerman Paul Zittel

CHEMillenniums, Classes of 1980–1999 These donors represent a participation rate of 5.5 percent for the CHEMillennium Era. Stuart and Sarah Adler Keith and Elaine Alexander Paul and Nicole Alivisatos Robert A. and Nancy H. Antonoplis Dr. John D. Arenivar Daniel and Shelley Arenson Phillip A. Armstrong Frances Arnold Kevin Austin Reha M. Bafrali* Douglas J. Bamford John Brennan and Jean Baum David B. Beach, Ph.D. Norman Peter and Eva Somer Belle Stacey F. Bent and Bruce M. Clemens Todd A. Blumenkopf Constantine G. Boojamra Marie T. Borin, Ph.D. Richard W. Borry Peter J. Brewer Richard Brodzinsky Steven Bromberg* Marilee Brooks Dave and Donna Brown Tim and Valerie Bruemmer Edward Bruggemann Gina Buccellato Stacey B. T. Bui Joel D. Burley

Mark A. Burlingame* Kristina M. Burow* Mark Camenzind Michael Carolan Ada Woo and Joe Carson Joan Frisoli and Harry Cartland Chu-An Chang Michelle and Jeffrey Chang Joan Chao Andrew Y. Cheng Gloria Cheng Rick Chin and Sandy Underwood C. Ching Dr. David L. Clark Jeffrey M. and Kerry L. Cogen James L. Cole* Paul A. Cornelius Virginia W. Cornish Dr. Matthew Croughan David C. Darwin Christopher Dateo Thomas and Cynthia Delfino Drs. Thomas J. Dietsche and Laura J. Dietsche Stephen G. DiMagno Richard Dionne* Pete Dragovich and Pei-Pei Kung Denis and Donna Drapeau Howard Drossman Daisy Joe and Justin Du Bois Lawrence H. Dubois Doug Edwards David Eichhorn Dr. Mark R. Etzel Eric Fallon Heather Fan Maria Fardis Paul L. Feldman Warren W. Flack William E. Fogle and Marilyn Wun-Fogle Stanley W. Fong Reyes M. Fragoso Elizabeth Green Francois Tim Frederick Leif G. and Janet L. Fredin Sabrina S. Fu and Philip J. Rous Jennifer Fujii

annual report ’06-’07

donors to the college CHEMillenniums Era donors, continued

Kent Fung Drs. Thomas R. Gadek and Katherine Neldner Hubert Gasteiger Michael B. Gentzler J. Daniel Gezelter* David Glueck David Godbey Avery Goldstein Gary M. Goncher Andrew Goodwin* Charles Goss Samuel L. Graham Beth M. Grasel Vicki Grassian and Mark Young Susan Graul Laura Greenfield Michael L. Greenfield David Guidry Tao Guo* Paul H. Gusciora Tan-Ngoc Ha* Neil S. Hanabusa Dr. Barry Hart and Ms. Kathleen McNutt-Hart Mark A. Hartney Scott Hecker Tana Woodward Henderson Frank Hershkowitz Charles Higdon Joel Hill Toshiaki Hino Eric Hintsa Herbert Hooper Donald Hou* Chris Hovde Hsin-Yuan Hu Zhengjie Hu and Wendy Ng Judy C. Huang and Ken A. Nishimura LiXuan Huang Michael R. Hull Mary Lee Hyde Mark J. and Alice H. Isaacson David Y. Jackson Ronald Jensen John A. Jensvold

College of Chemistry, UC Berkeley

Audrey Johnson Patricia A. Jones Andreas V. Kadavanich Michael Karim* Andrea L. Keaton Eric R. Keim Esayas Kelkile* Brian D. Kelley Carl S. Kellner Indu Kheterpal Ellen Kick Ed Kim Yesook Kim Andrew Kindler Jason C. King* James A. Klein Edward F. Kleinman Kevin A. Klotter Peter Knappe Janell Kobayashi Roland Koestner Tony Kovscek and Rebecca Taylor Deanne C. Krenz Cindy Krieger Stephen M. Lambert Bart Larrenaga Christina J. Lee* Fourmun Lee* Mei Kim Carol Lee Peter W. Lee Jan and Maria Leeman Philip M. Lessner Cissy Leung Suzanne Kam-Cee Leung Marc and Tsun-Tsun Levin Drs. Traci A. and Timothy A. Lewis John D. Leyba David Lieu, M.D., M.B.A. Dr. and Mrs. Nelson Lin Peter and Rachel Lipowicz Gary Lipscomb II Mingjun Liu Wai Leng Loh* S. Randolph Long Larry Loomis-Price Ed Louie Ka Lum Tom Mac Phee

Michael and Jane MacDonald Dr. Patricia D. Mackenzie Richard MacPhail Mary M. Mader Jon Maienschein and Lisa Cline Christopher A. Maines Doug Mandel Linda N. Marquez David W. M. Marr Toby (Horwitz) Massman* Kevin McAlea Michael J. and Janet Kim McCormick Karen and Steven McDonald Michael McKinney Kevin L. McLaren Ron Meeker Jeanlynn and Arjen Mets J. Hoyt Meyer* Richard Michelman and Karen Meyer Drs. Walter H. Moos and Susan M. Miller William M. Miller David Mobley T. Andrew Mobley* Lingfung Mok Rob Moore David W. Moreland Bob and Becky Mortlock Mike Moyer and Margaret Chu-Moyer Roberta N. Mulford Sean and Mary Mullen Curt Munson and Hazel Olbrich Herb Nelson Caroline Nguyen David A. O’Brien Anthony O’Keefe Miles S. Okino Adam S. Olgin Jackie Orbon Julie S. Oxner Roberto Pabalan Spyridon Papadakis John E. Parmeter Garry Iain George Parton Charles W. Paul Dehua Pei*

Jaan Pesti Dr. Eric C. Peters John and Cheryl Petersen Matthew Plunkett Darwin and Donna Poulos Kristala Jones Prather Max Pray Susan Puglia Nicholas Pugliano and Family Christina Lee Quigley Peter D. Quinn John A. Ragan R. Andrew Ramelmeier Gurdeep S. Ranhotra Tom and Betty Ransohoff Janice Reutt-Robey Jed L. Richardson Keith Rickert Alice Rico John L. Robbins Stephanie Robertson* Patrick A. Rodgers Mark Roebuck Steve R. Roffler and Bing-Mae Chen Mark E. Rosen David S. Rumschitzki Steven Russek Charles J. Russell* Philip P. Russell William Sailor, Ph.D. Edna Kazuko Sakai Alexander Sassi Erika Schneider, Ph.D. Drs. Steven Sciamanna and Sandy J. Roadcap Chris Lee and Scott Shaffer Anita J. Shaw George S. Sheppard Todd P. Silverstein Eric R. Sirkin John A. Smegal Randy Snurr Tonny Soesanto and Fay Sampoerna Dr. John E. Sohn Jeffrey P. Solar and Rosalyn Furukawa Ellen Lee and Michael Solomon

* New donor(s) in 2006–2007

Carla St. Laurent, M.D. David Stern Dr. Doris Stoermer Nancy and Mark Stoyer Warren C. Stueben John P. Sullivan Chris Tagge Rex Tam Janet Tamada Jeffrey Tane Klaus H. Theopold John F. Thompson Don and Rosemary Tilley Tracy Tram Dr. Andrew Trapani Victor and Susan Tsai David Uehling Ricardo Unikel Tetsuo Uno* Michael G. Valentine Renée van de Griend Paul Verderber Michael Verti Min-Chi Von Trentini David L. Wagger

Diane Wakeham* Deane S. Walker Timothy P. Walker Gloria Wang Lisa Wang Raymond Chiu and Stephanie Wang Marjorie and Greg Went Ronald M. Wexler David Whitmore Gary P. Wiesehahn Dr. Richard J. Wilcox James T. Williams Phillip A. Wilmarth Dr. and Mrs. Curt Wittig Chung M. Wong* Eric K. Wong Jack Wong Patrick M. Wong* Sharon M. Wong Adam Woolley Stephen Worland David T. Wu Liub-Chii Yang Chen Priscilla L. Yang and Nathanael S. Gray

Zhen-Yu Yang Grace Yap Laura Yee Steven D. Young Qing S. Yuan John L. Zelinsky* Ronald Zuckermann*

Young Alumni, 2000 and Beyond These donors represent a participation rate of 2.7 percent for the Young Alumni. Vladislav I. Afanasevich* Morris and Stephanie Argyle Rebecca E. Brafman Charles N. Buser II* Rossana Chan* Rida Y. Chow* Ellia Ciammaichella Dick T. Co Jacob M. Davis

Greg and Cristina Pitzer, Joan Arsenault and Ann Pitzer were guests at the Dean’s Dinner, where the Pitzer Family Foundation’s gift to Theoretical Chemistry was recognized.

Michelle M. Eastlack* Aihua Fu John Gavenonis Cynthia Gong* Alex Goretsky* Fanqing Guo* Eric Haas* Michael R. Harper* Jason Ho Dr. Jonathan Z. Ho Lisa M. Hochrein James D. Hoefelmeyer* Jolene M. Ignowski* Uwe Kirbach* Selene Koo Howard Lacheen* Jessica Lam* Chun-Yue Lee Wei-Luo Lee* Alice Lee-Dutra* Benjamin T. Liu* Ying Y. Lu* Tom Maimone Michael Milos Nate Neale John J. O’Brien Nicholas L. Ohler* Christine K. Payne* Jason Ploeger James R. Rice* Gregory A. Roberts* Ola M. Saad* Wayne E. Sackett* Joshua A. Schrier* Alan Sentman* Alan Tam* Sundiep K. Tehara Tellers Family Jennifer A. Tripp Adam Z. Weber* Karen M. Webster* Brandon T. Weldon* John J. M. Wiener* Shara C. Williams* Nicolas D. Winter* Joel E. Yeo* Adam Youngman* Rebecca Zuckerman

annual report ’06-’07

benefits of

private giving

THE ERIC B. ABRAMSON SCHOLARSHIP Lynelle Takihashi is a second-year chemistry graduate student in the Stephen Leone group. As a physics undergraduate at Berkeley, she showed an early interest in multidisciplinary research by working with the Richard Saykally group in the chemistry department on the spectroscopy of small water clusters. She currently is working with the Advanced Light Source at LBNL on using spectrometry to image cell surfaces. “The Eric B. Abramson award came as a great surprise for me,” says Takihashi, “and I am grateful for the honor. The award built my confidence as a new member of the chemistry department, and it has allowed me to charge forward with my studies and research.” Lynelle Takihashi

The Abramson Fund was established by family and friends of Eric Abramson, a graduate student who died in 1973. The fund has grown over the years and now supports two fellows per year.

benefits of

private giving

THE ERIC B. ABRAMSON SCHOLARSHIP Gabriela Schlau-Cohen was raised near Philadelphia, PA, in the same area as the Eric B. Abramson family. Schlau-Cohen attended Brown University as an undergraduate and graduated with a Sc.B. degree in chemical physics. At Berkeley, she is a member of Graham Fleming’s research group. The Fleming group is well known for studying the interactions between chromophores and the nanoscale engineering principles of natural photosynthetic light harvesting systems. These processes are ultrafast and require the use of femtosecond spectroscopy, where one femtosecond (10-15 seconds) is one millionth of one billionth of a second. “The Abramson award,” says Schlau-Cohen, “both helps fund our research and personally provides an important boost to my career.”

College of Chemistry, UC Berkeley

Gabriela Schlau-Cohen

* New donor(s) in 2006–2007

donors to the college Benjamin Ide Wheeler Society The Benjamin Ide Wheeler Society recognizes donors who have communicated to us their intention to include the College of Chemistry or the University of California, Berkeley, in their estate plans through some form of planned gift. Dr. Raul E. Acosta Dr. and Mrs. David Altman Charles E. and Marianne Auerbach William and Inez Benjamin Robert and Wendy Bergman Bud Blue Norbert C. and Florence M. Brady Robert J. Carr Sunney I. Chan Nirmal and Ellen L. Chatterjee T. Z. and Irmgard Chu Robin D. Clark and Mary Mackiernan Erna P. Clifford Warren E. Clifford Joyce Ekman Davis Dr. and Mrs. Gus D. Dorough, Jr. Arthur K. Dunlop Lois Durham Martha Dutro Warren W. Flack Dr. Peter C. Foller Kai-Ye Fung Anna Gatti William and Janet Gerhardt G. Douglas and Regina Gould Ruth Groch Susie Hahn Benjamin Haile Elizabeth S. Hall Clayton Heathcock and Cheri Hadley John F. Heil

Clinton and Joji Holzwarth Mr. and Mrs. Hubbard C. Howe, Jr. Richard W. Hyman Ernest Jacobson Nissen A. Jaffe Anne C. Johnson Prof. and Mrs. William L. Jolly Dr. Paul A. and Barbara W. Kittle Lance M. Krigbaum Dr. Joe B. Lavigne Richard M. and Lillian Lessler Tony K. and Louisa Ling Prof. and Mrs. David N. Lyon John M. McDonald Jacklyn Melchior Robert A. Micheli Prof. and Mrs. C. Bradley Moore Marjorie Pape Crandall Pearce June and Gene Roberts Michael S. Ross Harry N. and Jane L. Scheiber J. S. Paul Schwarz Hugh C. Silcox Henry B. Sinclair Mr. and Mrs. John R. Skinner Nora S. Smiriga Frank B. Sprow Bruce E. and Susan J. Stangeland Prof. and Mrs. Andrew Streitwieser, Jr. Nancy P. Taylor William Tolman Dr. J. A. Trainham and Dr. L. D. Waters Rita Wieland J. Michael M. Word Robert D. Zimmerman

Tributes Gifts have been received in honor of: Prof. Paul A. Bartlett Prof. Harvey W. Blanch E. Morse “Bud” Blue Samuel W. Calvert Dr. Michael D. Grimes, DPM Prof. Clayton H. Heathcock Prof. Harold S. Johnston Christopher Popeney Prof. John M. Prausnitz Prof. John O. Rasmussen Prof. Kenneth N. Raymond David B. Sable Prof. Herbert L. Strauss Prof. Andrew Streitwieser, Jr.

Gifts have been received in memory of: Peggy Abrahams Samuel Abrahams Eric B. Abramson Dr. Giulia Adesso Dr. Benjamin P. C. Boussert Prof. Leo Brewer Dr. Gary E. Brodale Todd A. Brooks Prof. Melvin Calvin Prof. James Cason Antonio T. Chong Dr. Jason L. Choy Prof. Burris B. Cunningham Dr. Henry G. Curme Louis R. Damskey, Jr. Prof. William G. Dauben Andrew Dorsey Dr. A. B. Falcone Prof. Irving Fatt Margaret M. Fuchs Dorothy Goerger Prof. William D. Gwinn Prof. Donald N. Hanson Vernon Haugen Dr. Heinz Heinemann Nancy K. Hildenbrand

Dr. Robert M. Ikeda Margaret Jorgenson Dr. Michael J. Keaton Liu Siok-Han Koo Dr. Frank Howard Kratzer John LaNotte Prof. Wendell M. Latimer Martha Lowe Prof. Bruce H. Mahan Kristen Malmquist William H. McAdams Gregory K. Meisner Dr. Aly Mohamed Prof. Donald S. Noyce Prof. Chester T. O’Konski Henry H. Otsuki Prof. Eugene E. Petersen Prof. George C. Pimentel Prof. Kenneth S. Pitzer Jonathan S. Powell Prof. Henry Rapoport Dr. Steven J. Rodgers Dr. Samuel Ruben Dr. Stan Rys Nart Savanapridi Prof. Glenn T. Seaborg Helen L. Seaborg Dr. Ashraf Shalaby Prof. Mitchel Shen Clayton Conner Shepherd Eugene F. Smith Charles and Irene Soulis Prof. Alexander S. K. Sun Dr. Tamara W. Suslov Dr. Stanley G. Thompson Prof. Charles W. Tobias Dr. Himanshu B. Vakil Prof. Theodore Vermeulen Prof. Charles R. Wilke

annual report ’06-’07

donors to the college 2005–2006 Donors Who Increased Their Support by 10% or more in 2006–2007

Keith and Elaine Alexander Ward and Mary Alter Dr. and Mrs. David Altman Dr. Habib Amin Myron and Barbara Andrews Daniel and Shelley Arenson Phillip A. Armstrong David Bass Carl M. Berke John H. Birely Dr. Tom A. Bither, Jr., and Mrs. Margaret V. Bither Bud Blue M. Robert Blum Constantine G. Boojamra Marie T. Borin, Ph.D. Mr. and Mrs. Marvin Brafman R. R. Breckenfeld Robert J. Breuer Ardra C. Brodale Dave and Donna Brown Tim and Valerie Bruemmer Charles Buse James L. Caley William and Joyce Chang Margaret and Nai Chen Tan-Jen and Li-Fong Chen Gregory K. Chow T.Z. and Irmgard Chu Shelley Claridge Robin D. Clark and Mary Mackiernan Tucker Coughlen David C. Darwin Clelland R. Downs Carol Dunbar Arthur K. Dunlop Ernest Ehnisz, Jr. Dr. Julianne Elward-Berry Alan S. Emanuel Dr. Mark R. Etzel William H. Eustis John Fabera Dr. Patricia L. Falcone and Family Maria Fardis Dr. Robert J. Farina Kenneth G. Felton College of Chemistry, UC Berkeley

Bruce A. Firestone, Ph.D. Michael and Mary Flaugh William E. Fogle and Marilyn Wun-Fogle Dr. and Mrs. Howard L. Fong Matthew K. Fountain Reyes M. Fragoso Charles and Margaret Frazier Philip R. Friedel Friends of Eric Abramson Scholarship Fund Aihua Fu Kent Fung Michael B. Gentzler Indu Kheterpal Gary M. Goncher G. Douglas and Regina Gould Beth M. Grasel Michael L. Greenfield Virginia-Jane Harris Clayton Heathcock and Cheri Hadley Jessie Herr Louis and Nellie Herrington Dr. Jonathan Z. Ho Herbert Hooper Irma Hrycyk Zhengjie Hu and Wendy Ng Michael R. Hull Adrienne Iwata William Y. Ja Audrey Johnson Russell D. Johnson, Jr. Dr. and Mrs. Andrew Kaldor Dr. Max J. Kalm Andrea L. Keaton Stanley Kelly T. P. King William A. Kleschick Prof. Judith P. Klinman Janell Kobayashi Roland Koestner Dr. Aaron D. Kossoy Romesh Kumar James and Barbara Lago Mei Kim Carol Lee James W. Lewis John D. Leyba David A. Lightner Elaina Lin S. Randolph Long Dick and Myra Lynch Michael and Jane MacDonald Prof. Bruce H. Mahan Estate Arturo Maimoni

Prof. Samuel and Mrs. Lydia Markowitz Gary and Irene Masada Paul and Julia Mathews Michael J. and Janet Kim McCormick Karen and Steven McDonald Michael McKinney Kenneth E. Meeker Charles and Diane Meyer Donald G. Miller Michael Milos Merrill A. Muhs Dr. and Mrs. Louie Nady Albert Narath Nate Neale Herb Nelson Walter E. Nervik David R. Nethaway Prof. and Mrs. John S. Newman Joan Friedman Newmark and Richard Newmark T. W. Newton Allen Ng Douglas J. Ng Yu Sim Ng Felix G. Ngan and Lily M. Lee Caroline Nguyen Heino Nitsche and Martha Boccalini Nancy Norem John J. O’Brien Kent Opheim Robert J. Ouellette Harlan and Stanislava Overholt, Jr. Rodney and Jeanne Panos William R. Parrish Leonidas Petrakis David B. Phillips Norman and Paula Phillips Jonathan S. Powell Prof. and Mrs. John M. Prausnitz Jack M. Rademacher Lanny Replogle Jed L. Richardson John L. Robbins June and Gene Roberts Scott Rocklage Klaus and Mary Ann Saegebarth Elmer E. Schallenberg Dr. and Mrs. Francis J. Schmitz

Nick R. Schott Stephen E. Schwartz Drs. Steven Sciamanna and Sandy J. Roadcap Anita J. Shaw Albert E. Sherwood Martin D. Shetlar Hugh C. Silcox Sher G. Singh Mary F. Singleton Randy Snurr Jeffrey P. Solar and Rosalyn Furukawa Judith and Gabor Somorjai Julie Stewart Elise C. Stone Elaine Blatt Stoner Dr. James S. Symanski Rex Tam Kong-Heong Tan Vazken Tashinian Sheila E. Taylor Richard M. Teeter Barbara A. Tenenbaum Anne Friend Thacher Jack Thomas Curtis Tong George L. Tong Dr. J. A. Trainham and Dr. L. D. Waters David Uehling Ricardo Unikel Renée van de Griend Dale E. Van Sickle Mathias van Thiel Raymond Vermeulen James P. Vokac and Stacey T. Baba Anthony C. Waiss, Jr. Jennifer S. Wakita Mark Wegner Robert F. Weimer R. B. Weisenmiller, Ph.D. Willard M. Welch Shara C. Williams* Phillip A. Wilmarth Mr. and Mrs. Arthur T. Wincek Connie Wong Eric K. Wong Jack Wong Stephen Worland Liub-Chii Yang Chen Laura Yee Qingqi Yue and Huaixia Yao

2006-07

college advisory board John H. Abeles MedVest Inc. Richard C. Alkire M.S. ’65; Ph.D. ’68, ChemE University of Illinois at Urbana-Champaign William Banholzer Dow Chemical Company Larry Bock Lux Capital Nirmal “Chat” Chatterjee M.S. ’68, Ph.D. ’71, ChemE Air Products and Chemicals (retired) Carl P. Decicco Bristol-Myers Squibb Sam H. Eletr Ph.D. ’68, Chem Population Genetics Stephen P. Fodor Post-doc ’91, Chem Affymetrix Inc. Robert H. Grubbs California Institute of Technology Victoria F. Haynes B.A. ’69, Chem RTI International F. Emil Jacobs ExxonMobil Research and Engineering Company M. Ross Johnson Post-doc ’71,Chem Parion Sciences, Inc. Daniel E. Koshland, Jr. B.S. ’41, Chem UC Berkeley Yuan Tseh Lee Ph.D. ’65, Chem Academia Sinica and UC Berkeley Richard A. Lerner Scripps Research Institute Richard M. Levy Ph.D. ’65, Chem Varian Medical Systems John H. Markels Ph.D. ’94, ChemE Merck & Company Gary M. Masada B.A. ’66, Chem Chevron Information Technology Alan Mendelson Latham & Watkins, LLP Mario J. Molina Ph.D. ’72, Chem UC San Diego JoAnne Stubbe Ph.D. ’71, Chem Massachusetts Institute of Technology James A. Trainham B.S. ’73, Ph.D. ’79, ChemE PPG Industries R. Stanley Williams M.S. ’76, Ph.D. ’78, Chem Hewlett Packard

volunteers Alumni Association Steering Team Gilbert T. Basbas, B.S. ’04, ChemE Bud Blue, B.S. ’34, Chem Gordon G. Chu, B.S. ’03, ChemE Laurie J. Dockter, B.A. ’71, Chem Marissa Drouillard, B.S. ’00, Chem Mark W. Ellsworth, Ph.D. ’93, Chem Samuel J. Gillette, Ph.D. ’00, Chem Lara A. Gundel, Ph.D. ’75, Chem Deanne C. Krenz, B.S. ’94, Chem Lawrence B. Perry, B.S. ’56, ChemE Daisy Y. Quan, B.S. ’47, Chem Steven F. Sciamanna, B.S. ’79, Ph.D. ’86, ChemE Rebecca Zuckerman, Ph.D ’00, Chem

Alumni Era Volunteers The following have volunteered their time in the Alumni Association’s “era groups.” G. N. LEWIS ERA: 1945 AND EARLIER

Bud Blue, B.S. ’34, Chem G. Douglas Gould, B.S. ’42, Chem

THE FREE RADICALS: 1964–1979

Laurie J. Dockter, B.A. ’71, Chem Robert P. Hohmann, B.S. ’78, ChemE Curtis L. Munson, B.S. ’76; Ph.D. ’85, ChemE Carolyn M. Orelli, B.S. ’70, Chem Steven F. Sciamanna, B.S. ’79; Ph.D. ’86, ChemE Bruce E. Stangeland, Ph.D. ’67, ChemE THE CHEMILLENNIUMS: 1980–1999

Marilee M. Brooks, M.S. ’88, ChemE Paul V. Burke, B.S. ’81, ChemE Joel D. Burley, Ph.D. ’91, Chem Grace F. Chou, Ph.D. ’88, ChemE Daisy J. Du Bois, Ph.D. ’94, Chem Mark W. Ellsworth, Ph.D. ’93, Chem Maria S. Fardis, Ph.D. ’98, Chem Thomas R. Gadek, Ph.D. ’86, Chem Deanne C. Krenz, B.S. ’94, Chem Susan M. Miller, Ph.D. ’83, Chem Walter H. Moos, Ph.D. ’82, Chem Alyssa L. Roche, B.S. ’87, ChemE Steven F. Sciamanna, B.S. ’79, Ph.D. ’86, ChemE Michael M. H. Yang, B.S. ’92, ChemE Sheila W. Yeh, B.S. ’80, Ph.D. ’86, Chem

CUPOLA ERA: 1946-1963

Frank G. Delfino, B.S. ’51, ChemE E. Kenneth Hulet, Ph.D. ’53, Chem David N. Lyon, Ph.D. ’48, Chem Mary F. Singleton, M.S. ’59, Chem

Fundraising Volunteers The following assisted the College in fundraising efforts in 2006–07. Andreas Acrivos Richard C. Atkinson Tom A. Bither, Jr., B.S. ’39 Bud Blue, B.S. ’34, Chem T. Z. Chu, B.S. ’58, Chem William A. Daniels, B.S. ’56, ChemE Kai-Ye Fung, B.S. ’79, ChemE William Gerhardt, B.S. ’60, ChemE G. Douglas Gould, B.S. ’42, Chem John E. Hearst L. Louis Hegedus, Ph.D. ’72, ChemE Michael C. Kavanaugh, M.S. ’64, ChemE C. Judson King Virginia Lew, B.S. ’61, Chem Robert Lindquist, Ph.D. ’55, Chem Robert E. Lundin, Ph.D. ’55, Chem John H. Markels, Ph.D. ’94, ChemE Mario J. Molina, Ph.D. ’72, Chem Joon S. Moon, Ph.D. ’64, ChemE Jeanne R. Pimentel Daisy Quan, B.S. ’47, Chem Milton H. Ritchie, B.S. ’51, Chem Steven F. Sciamanna, B.S. ’79, Ph.D. ’86, ChemE Farhang Shadman, M.S. ’69, Ph.D. ’72, ChemE David H. Templeton, Ph.D. ’47, Chem

YOUNG ALUMNI: 2000 AND BEYOND

Stephen Chan, B.S. ’01, ChemE Marissa Drouillard, B.S. ’00, Chem Samuel J. Gillette, Ph.D. ’00, Chem Rebecca Zuckerman, Ph.D. ’00, Chem

annual report ’06-’07

corporate, foundation and organizational gifts

It is our pleasure to acknowledge the many companies and other organizations that continue to invest in the collegeâ&#x20AC;&#x2122;s future. These donations represent a major source of funding for our graduate, research and teaching programs. Contributions for 2006â&#x20AC;&#x201C;07 are listed below.

Industrial Friends Program Membership in the College of Chemistry Industrial Friends Program is open to any firm, regardless of size or location. Support can come in the form of unrestricted funds, departmental fellowship funds, start-up funds for non-tenured faculty, support for facilities or support of research of tenured faculty. 62

INDUSTRIAL FRIENDS OF THE COLLEGE OF CHEMISTRY

Annual contributions of $30,000 or more ($50,000 for support of the research of tenured faculty) that benefit the Department of Chemistry and the Department of Chemical Engineering, or the College of Chemistry. Arkema Inc. Chevron Corporation Dow Chemical Company Merck Roche Palo Alto Rohm and Haas Company Tyco Electronics

College of Chemistry, UC Berkeley

INDUSTRIAL FRIENDS OF THE DEPARTMENT OF CHEMICAL ENGINEERING

Annual contributions of $15,000 or more ($50,000 for the support of a tenured faculty member) that benefit the Department of Chemical Engineering. 3M Alcon Research Ciba Vision Corporation CooperVision, Inc. Ford Motor Company KLA Tencor Lam Research Corporation Robert Bosch Corporation Semiconductor Research Corporation Tokyo Electron, Ltd. INDUSTRIAL FRIENDS OF THE DEPARTMENT OF CHEMISTRY

Annual contributions of $15,000 or more ($50,000 for the support of a tenured faculty member) that benefit the Department of Chemistry Abbott Laboratories Amgen, Inc. AstraZeneca Boehringer Ingelheim Pharma Bristol-Myers Squibb CrystalGenomics DuPont Elan Pharmaceuticals Eli Lilly and Company Gilead

GlaxoSmithKline Novartis Institutes for Biomedical Research, Inc. NuvoMetrix, Inc. Pfizer Inc. Schlumberger Theravance

Gifts of $100,000 and more American Cancer Society Bristol-Myers Squibb Burroughs Wellcome Fund Camille and Henry Dreyfus Foundation Eli Lilly and Company Gilead Sciences Jane Coffin Childs Memorial Fund Lam Research Novartis Institutes for Biomedical Research, Inc.

Gifts of $25,000 to $49,000 3M Abbott Laboratories American Chemical Society, Division of Organic Chemistry American Chemical Society, Petroleum Research Fund Amgen, Inc. Arkema Inc. CooperVision, Inc. Dow Chemical Company Ford Motor Company Genentech Inc. Max Kade Foundation Merck Roche Palo Alto Schlumberger Semiconductor Research Corporation Tokyo Electron Ltd.

Gifts up to $24,999 Gifts of $50,000 to $99,000 American Heart Association Boehringer Ingelheim Pharma Chevron Corporation Ciba Vision Corporation CrystalGenomics DuPont GlaxoSmithKline Robert Bosch Corporation Rohm and Haas Company Tyco Electronics

BP International Dainippon Sumitomo Pharma Company, Ltd. ExxonMobil Holtzbrinck Publishing Holdings Johnson Matthey Inc. Ono Pharmaceutical Co. Ltd OnWafer Technologies, Inc. Organic Syntheses, Inc. Pfizer Inc. Philip Morris U.S.A. Procter & Gamble Company

Royal Society of Chemistry Sangamo Biosciences Inc Springer-Verlag New York Statoil Theravance, Inc.

Matching Gifts 3M Foundation, Inc. A T & T Foundation Advanced Micro Devices AEP Service Corporation Agilent Technologies Air Products & Chemicals Inc. Allstate Insurance Altria Inc. Amgen Foundation Applera Corporation Autodesk Inc. Avon Products Beckman Coulter Boeing Company BP Amoco Foundation, Inc. Bridgestone/Firestone Trust Fund Bristol-Myers Squibb Chevron Corporation Clorox Company Foundation ConocoPhillips Dow Chemical USA Eli Lilly and Company Foundation Elsevier Foundation ExxonMobil Foundation Fidelity Foundation Fluor Corporation GenCorp Foundation Inc. Genentech General Electric Foundation General Motors Foundation Georgia Power GlaxoSmithKline Hess Corporation Hospira IBM Corporation IFF Foundation

Illinois Tool Works Foundation Intel Foundation Johnson & Johnson Johnson Controls Foundation Lockheed Martin Longs Drugs Lyondell Chemical Co. Medtronic Menasha Corp Foundation Merck Monsanto Fund National Starch

Northrop Grumman Corp OSIsoft PepsiCo Pfizer Inc. Pharmacia & Upjohn Foundation Pioneer Hi-Bred International PNM Foundation Raytheon Company San Diego Gas & Electric Schering-Plough Corporation Shell Oil Company Foundation

Spansion State Farm Sun Microsystems Takeda Tektronix Foundation Valero Energy Corporation Walt Disney Company Foundation Washington Group Foundation Wells Fargo Wyeth (American Home Products Corporation)

Lam Research staff visit the college to discuss partnership opportunities. From left to right, Edwin Sum (B.S. ’78, ChemE), Product Development Program director Keith Alexander (Ph.D. ’83, ChemE), Thalia Kong (B.S. ’95, ChemE), Eric Hudson (Ph.D. ’93, Chem), dean Charles Harris, chemical engineering chair Jeff Reimer and Rick Gottscho.

annual report ’06-’07

giving to the college of chemistry college funds T H E A N N U A L F U N D provides essential monies that can be used, at the discretion of the dean or of the chairs, to meet needs that are not supported by the state budget. These unrestricted funds are particularly valuable because of their flexibility. The annual fund is vital for financing ongoing programs and special projects. E N D O W E D F U N D S provide a permanent source of income to meet the needs of faculty and students in perpetuity.

M E M O R I A L F U N D S commemorate individuals while benefiting the College and the Departments of Chemistry and Chemical Engineering. Memorial funds include those honoring Samuel Abrahams, Eric Abramson, Leo A. Berti, Donald Blakely, Benjamin Boussert, Gary E. Brodale, Charles J. Busso, Melvin Calvin, Cynthia Ann Chan, William Dauben, Shirley DeBuhr, A. B. Falcone, Irving Fatt, William Gwinn, Heinz Heinemann, Joel Hildebrand, Bruce Howard, Frederick “Fritz” Jensen, Margaret Jorgenson, G. N. Lewis, Bruce Mahan, Kristin Malmquist, Earl Muetterties, Eugene E. Petersen, George Pimentel, Kenneth S. Pitzer, William H. and Mary Rees, Samuel Ruben, Erich O. and Elly Saegebarth, Glenn T. Seaborg, Mitchel Shen,Vincent James Starr, Stanley G. Thompson, Charles Wilke, and Theodore Vermeulen. Donations may also be given to the annual fund in memory or in honor of an individual, and the college will notify the family that a contribution has been made.

College of Chemistry, UC Berkeley

forms of giving benefits for the college — and for the donors Many different kinds of gifts can benefit both you and the University. Some of them can offer particular estate planning advantages, including income for life. Our professional staff would be pleased to discuss these gift vehicles with you; however, the University urges you also to consult your attorney or financial advisor. If you wish your gift to benefit the college, any legal documents or instructions should specify that the gift is for the College of Chemistry (or the Department of Chemistry or the Department of Chemical Engineering) at the University of California, Berkeley. C A S H Checks should be made payable to the UC Berkeley Foundation (UCBF), with a notation designating the name of the fund. Gifts to memorial funds should be made payable to the specific fund. Contributions may also be made with your Visa or MasterCard credit card by phone (510/642.8782), or online at http://chemistry.berkeley.edu/givetochem. S E C U R I T I E S In most cases, gifts of appreciated securities may be deducted at full market value as of the date you make the gift, and the donor does not have to pay capital gains taxes. Gifts of appreciated stock are most easily handled by the UC Berkeley Foundation and should not be sold prior to transfer. You or your broker may contact Assistant Dean Jane Scheiber in the college (510/642.8782) or Ms. Sylvia Worthington, Securities Steward in University Relations (510/642.4123), for further information. Stock can often be transferred electronically. If you wish to give a gift of depreciated stock, you should first sell it and give the proceeds to the

Foundation. You can then use the loss to offset any gains and also claim a charitable deduction. R E A L E S TAT E Gifts of real property may be deeded to UC Berkeley for the benefit of the College of Chemistry, providing significant tax advantages to the donor in most cases. It is also possible to deed a property to the University and continue to occupy it for life. L I F E I N C O M E G I F T S A number of options are available by which you may transfer assets to a trust (to be managed either by the University or a trustee of your choosing) and receive income for yourself and/or a designated beneficiary for life, as well as immediate tax benefits. The college ultimately receives the trust property. B E Q U E S T S A fixed amount or a percentage of your estate may be designated for the benefit of the College of Chemistry in your will or living trust. M AT C H I N G G I F T S Hundreds of firms match their employees’ (and sometimes retirees’) contributions on a 1:1, 2:1 or even 3:1 basis. If your company has such a policy, forms—hard copy or electronic— to assure that your gift will be matched can be obtained from your personnel or employee relations office. Matching gifts are added to your individual gift in determining the donor club to which you belong. I R A R O L L O V E R S Until December 31, 2007, you can transfer a gift from your IRA account directly to the UC Berkeley Foundation without first paying taxes — if you will be 70 1/2 or older by that date. For further information, contact Jane Scheiber at 510/642.8782.

archive THE REPORT OF PRIVATE GIVING COLLEGE OF CHEMISTRY 2006â&#x20AC;&#x201C;2007

The preceding report acknowledges all donors to the College of Chemistry from July 1, 2006 through June 30, 2007. We have made every attempt to include all donors accurately. We apologize for any errors or omissions and would appreciate hearing from you with any comments or corrections regarding the publication.

assistant dean Jane Scheiber editor Michael Barnes director of development Mindy Rex director of annual giving and corporate and foundation relations Nancy Johnsen Horton development services manager Dorothy Isaacson Read

For further information about giving to the College of Chemistry, please contact College Relations College of Chemistry #1460 University of California, Berkeley Berkeley, CA 94720-1460 Phone: 510/642.8782 Fax: 510/642.4419 Email: jscheib@berkeley.edu

W i t h t h i s l e t t e r, d a t e d J a n u a r y 8 , 1 9 5 7 , chemical engineeringâ&#x20AC;&#x2122;s Charles Tobias welcomes Gabor Somorjai to UC Berkeley. Somorjai, a student leader in the 1956 Hungarian Revolution, had escaped to the west just a few months earlier with his sister, Marietta, and his girlfriend (and later wife), Judith Kaldor.

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Upcoming 2008 Alumni Events Cupola Era Alumni Luncheon February/March Watch for a separate mailing with details of this event.

Cal Day April 12

This annual campus-wide open house has something for everyone! As the date draws near, check out Berkeley.edu/calday for a complete listing of the events.

Springfest and Graduating Student Reception April/May Join us for this festive event as we celebrate the graduating students. Watch for an e-mail and visit our homepage at chemistry@berkeley.edu to learn more details as the time approaches.

MIT-Stanford-UC Berkeley Nanotechnology Forums Log on to mitstanfordberkeleynano.org to learn about these monthly seminars.

Berkeley Nanotechnology Forum April The Berkeley Nanotechnology Forum 2008 (BNF 2008) features leading scientists, entrepreneurs and academics presenting their views on current achievements and future opportunities in the field of nanotechnology. For more information, visit nanoclub.berkeley.edu.

+ Update! The campus now has an online calendar network which will make it easier to find events of your special interest! Go to events.berkeley.edu to view the wide array of programs and events on campus. And remember, College of Chemistry events can be found at chemistry.berkeley.edu â&#x20AC;&#x201C; select Seminars and Events.

+ For a list of College of Chemistry seminars, please go to chemistry.berkeley.edu â&#x20AC;&#x201C; select Seminars and Events.

+ For alumni events, see chemistry.berkeley.edu/alumni/events.html.

background image: rayograph courtesy of michelle douskey