Department of Pediatrics 2020-2021 Annual Report by UHMed JABSOM

Department of Pediatrics

2020-2021 Annual Report

John A. Burns School of Medicine University of Hawaii

The University of Hawai'i John A. Burns School of Medicine was established in 1965 as a two year basic medical sciences program and subsequently became a four year degree program effective 1973. All of the Clinical Science Program are located in the affiliated hospitals with the Department of Pediatrics located at Kapi'olani Medical Center for Women and Children.

Department of Pediatrics, 2021 Annual Report

Annual Report

Table of Contents 4 5 6 - 14 17

EDITOR’S NOTE

67 Departmental Research Report

17 Division of Community Pediatrics 27 Division of Pediatric Emergency Medicine of Pediatric Hematology and 29 Division Oncology 32 Division of Pediatric Hospitalist

PEDIATRIC RESEARCH

66 2020-2021 By the Numbers

DIVISIONAL REPORTS

22 Division of Neonatal-Perinatal Medicine

DEPARTMENTAL EDUCATIONAL ACTIVITIES

64 Pediatrics Thursday Grand Rounds

CHAIR MESSAGE

COMPENSATED & NON-COMPENSATED CLINICAL FACULTY ROSTERS

2020-2021

Research and Training Grants 68 Extramural and Contracts

HONORS & ACHIEVEMENTS

72 Faculty Awards

36 Division of Pediatric Intensive Care

DEPARTMENTAL PUBLICATIONS & PRESENTATIONS 74 Division of Community Pediatrics

40 Division of Pediatric Specialty

75 Division of Neonatal-Perinatal Medicine

TRAINING PROGRAM HIGHLIGHTS

77 Division of Pediatric Emergency Medicine

51 Class of 2021 Graduate Careers Selections

of Pediatric Hematology and 80 Division Oncology

52 2021-2022 Incoming Interns

82 Division of Pediatric Hospitalist

53 Pediatric Residency Roster

85 Division of Pediatric Intensive Care

54 Resident Honors and Awards

86 Division of Pediatric Specialty

55 Resident Research Infrastructure

MEDICAL STUDENT ACTIVITIES

59 Pediatric Interest Group 62 Clinical Skills Preceptorship (CSP) Tutors

Department of Pediatrics, 2021 Annual Report

Message from the Editor

Our continued challenges with the ongoing pandemic has once again delayed out release of this annual report. Special thank you to this year’s design and layout editor Huanli Hu, our departmental administrative support, for with her assistance, we were able to effect some small design changes to assist in making this report compact in the coming years. It is always a rewarding task for me to review and provide editorial oversight as I become aware of many of the activities in the department which have no other forum to be reported in. The Departmental Goal is still to provide a composite of departmental activities during the 2020-21 academic year and I hope you will find that this document fulfils that goal. If there are areas which could be further targeted for more detailed information please do not hesitate to provide the feedback. Please continue to provide feedback not only on this document but also the Departmental website https://pediatrics.jabsom.hawaii.edu to make our web presence meaningful and valuable to all.

Venkataraman Balaraman, MBBS Department Vice-Chair

Department of Pediatrics, 2021 Annual Report

Department of Pediatrics

Message from the Chair

In now year 2 of the COVID pandemic, we continue to empathize with those who have suffered losses and reflect on the resilience that has tested the resolve of many. With this resilience and resolve, our faculty, residents and staff are pleased to share our 2020-2021 annual report of our Department of Pediatrics, University of Hawaii, John A. Burns School of Medicine. The COVID-19 pandemic continues to accelerate changes in the way we provide medical education as well as the way we practice. Our willingness and commitment to look “Beyond” has created opportunities for exciting change.

Every system is perfectly designed to produce the results it gets.” – Paul Batalden, MD We remain steadfast however, through these changes, in our promise to educate pediatricians to provide the physician workforce for our state, participate actively in scientific discovery and quality improvement, and partner with all entities involved in pediatric services. Collectively, this provides the best care for all children in our state. HPH, the health care system that houses our program, has a mission, “to create a healthier Hawai‘i”. Likewise, this is our mission. Health vs health care, health equity, addressing needs outside of the traditional health care system, are now an even greater part of our mission-based kuleana (responsibility).

in science and what is practiced. This is one of the important ways we maintain the trust and leadership in our community.

Our excuses for why we can’t improve sound lame when patients are in the room.“ - James Reinertsen, MD Hawaii is consistently rated by Gallop as one of the top states in the nation for well-being. In part, the strong sense of connectivity with family and community found here promotes our well-being. Our embracement of community and learning from our patients and families by listening to their stories has made community an even bigger influencer of how we recruit for fit in the residents, faculty and staff that join us. The core of our department remains our people: faculty, residents, students and staff. We are proud of and celebrate their accomplishments herein. Our deepest gratitude is extended to the leadership and staff of Kapi‘olani Medical Center for Women & Children, Hawaii Pacific Health, the John A. Burns School of Medicine, University of Hawaii and all pediatric partners in the state. Their support makes our mission to serve Hawaii’s children achievable. Finally, my personal gratitude and mahalo (thank you) is extended to Dr Venkataraman Balaraman, who tirelessly continues as the editor of this year’s report.

Kenneth T. Nakamura, M.D. Professor and Chair

As the academic arm of our state’s pediatric system of care, we continue to contribute to the science of practice and to narrow the gap between what is known

Department of Pediatrics, 2021 Annual Report

Compensated & Non-Compensated Clinical Faculty Rosters

Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Leadership

DEPARTMENTAL GOVERNANCE LEADERSHIP Kenneth T. Nakamura, MD Chair

Venkataraman Balaraman, MBBS Vice Chair Interim Associate Chair for Research

Kyra Len, MD Loren Yamamoto, MD David Kurahara, MD Marissa Fakaosita, MD Wade Kyono, MD Shilpa Patel, MD Kara Wong Ramsey, MD New member effective AY 2021

Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Leadership

PEDIATRIC RESIDENCY PROGRAM LEADERSHIP David Kurahara, MD Program Director

Jennifer Di Rocco, DO Associate Program Director

Gina French, MD Associate Program Director

Marissa Fakaosita, MD Recruitment & Selection Co-Chair

Marian E. Melish, MD Recruitment & Selection Co-Chair

Andrew Feng, MD Program Evaluation Committee Chair

NEONATAL PERINATAL MEDICINE (NPM) FELLOWSHIP PROGRAM LEADERSHIP Venkataraman Balaraman, MBBS Program Director

Lee Brock, MD Associate Program Director Assistant Clinical Professor Neonatal Perinatal Medicine, Tripler Army Medical Center

Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Professors

David Kurahara, MD

Marian E. Melish, MD

James E. Musgrave, MD

Kenneth T. Nakamura, MD

Rheumatology

Infectious Diseases

Nephrology

Chair

Charles Neal, MD, PhD*

Robert W. Wilkinson, MD

Loren G. Yamamoto, MD, MPH, MBA

Neonatal-Perinatal Medicine

Hematology/Oncology

Richard T. Yanagihara, MD, MPH

Emergency Medicine

David Easa, MD

Raul Rudoy, MD, MPH

Professor Emeritus Am. Lung Assoc. Endowed Chair

Professor Emeritus Infectious Diseases

Infectious Diseases

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021

Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Associate Professors

Venkataraman Balaraman, MBBS

Andras Bratincsak, MD, PhD

Paul J. Eakin, MD*

Gina M. French, MD

Vice Chair

Cardiology

Emergency Medicine

Ambulatory Pediatrics

Lynn M. Iwamoto, MD

Jannet J. Lee-Jayaram, MD

Kyra A. Len, MD

Sheree Kuo, MD

Neonatal-Perinatal Medicine

Emergency Medicine

Hospitalist

Neonatal-Perinatal Medicine

May Okihiro. MD

Shilpa J. Patel, MD

Randal K. Wada, MD*

Community Pediatrics

Hospitalist

Hematology/Oncology

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021 Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Assistant Professors

Keith Abe, MD

Teresa Bane-Terakubo, MD

Maureen O.J. Chang, MD

Rupert Chang, MD

Selina Chen, MD

Neurology

Ambulatory Pediatrics

Critical Care Medicine

Hospitalist

Kelley Chinen Okimoto, MD

Diane P. Ching, MD

Natascha Ching, MD

Jennifer Di Rocco, DO

Megan Doty, MD

Hematology/ Oncology

Hospitalist

Infectious Diseases

Hospitalist

Neonatal-Perinatal Medicine

Leah Dowsett, MD

Marissa Fakaosita, MD

Andrew Feng, MD

Darryl W. Glaser, MD

Genetics

Hospitalist

Critical Care Medicine

Pia Francisco-Natanauan, MD

Hematology/Oncology

Adolescent Medicine

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021 Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Assistant Professors

John Jaime Harrington III, MD*

Travis Hong, MD

Jasmin Jensen, MD

Jennifer R. King, DO

Jeremy L. King, DO

Critical Care Medicine

Emergency Medicine

Hematology/ Oncology

Sports Medicine

Gastroenterology

Jessica S. Kosut, MD*

Mae S.I. Kyono, MD

Wade T. Kyono, MD

Rhiana Lau, MD*

Anna-Lena Lueker, MD

Hospitalist

Ambulatory Pediatrics

Hematology/ Oncology

Nephrology

Hospitalist

James C. Lin, MD

Maya Maxym, MD

Desiree Medeiros, MD

Joan Meister, MD

Barry M. Mizuo, MD

Hospitalist

Hematology/ Oncology

Ambulatory Pediatrics

Hospitalist

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021 Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Assistant Professors

Kayal Natarajan, MD

Brenda M. Nishikawa, MD

Cheryl Okado, MD

Jeffrey K. Okamoto, MD

Amanda O’Kelly, MD

Child Abuse Pediatrics

Ambulatory Pediatrics

Ambulatory

Developmental/ Behavior Pediatrics

Psychiatry

Gina Ramirez, MD

William Shea, MD

Sneha L. Sood, MD

Len Y. Tanaka, MD, MS

Alicia Turlington, MD

Hospitalist

Neonatal-Perinatal Medicine

Critical Care Medicine

Ambulatory Pediatrics

Tiffany Wang, MD

Kara Wong Ramsey, MD

Yolanda C. Wu, MD

Konstantine Xoinis, MD

Kara S. Yamamoto, MD

Hospitalist

Neonatal-Perinatal Medicine

Ambulatory Pediatrics

Critical Care Medicine

Rheumatology

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021 Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Assistant Professor & Instructors

Cherilyn Yee, MD Neonatal-Perinatal Medicine

Instructors

Chanel Casamina, MD

Vinson Diep, MD

Medical Education

*Division Chief The University of Hawaii is an equal opportunity/affirmative action institution. 2020-2021 Department of Pediatrics, 2021 Annual Report

CONGRATULATIONS

2021 FACULTY PROMOTIONS

Paul J. Eakin, MD

Sheree Kuo, MD

Promoted to Associate Professor

Jannet Lee-Jayaram, MD

Kyra Len, MD

Promoted to Associate Professor

Department of Pediatrics, 2021 Annual Report

University of Hawaii John A. Burns School of Medicine Department of Pediatrics

Clinical Faculty 2020-2021 Clinical Professors Melinda Ashton Beatriz Rodriguez Rodolfo Begue Rodney Boychuk Dominic Chow

Ellen Raney Gregory Dever Anthony Guerrero Christine Hara Keith Matsumoto

Robert Anderson Kenneth Ash Robert Bidwell Galen Y.K. Chock Christopher Mahnke

Robert Durkin Paul Eakin Vanessa Fidele Edward Fong Franklin S.H. Young Ronald H. Hino

Kenn Saruwatari Ken Nagamori Robert H Pantell Vijaya Reddy Reinhold Penner

Clinical Educators Kenneth Robbins Stephen S. Yano Ronald Sutherland Mitsuaki Suzuki Wallace J. Matthews Jr.

Lynn Yanagihara

Associate Clinical Professors Alson Inaba Indi Trehan Byron Izuka Shigeko O. Lau Linda Rosen‐Debold Leah McMann

Bryan Mih Michon Morita Sada Okumura Patrick Murray Michael Sia Wesley Sugai

Lenhanh Tran Greg Uramoto Russell Woo Gregory Yim Tamara Zagustin

Assistant Clinical Professors Christopher B. Stefanelli Toyin Ajose Alicia Prescott Richard E. Ando, Jr. David Ansdell Art Wong Ashley Maranich Vernon Azuma Frank Baum Timothy Beaty Eric Boorman Dona Brekke Brian J. Wilson Brittany Raffa Lee Brock Jason Brown Daniel Buehler William Burkhalter Mark Burnett Miki Cain Matthew Careskey Brigitte Carreau Sean Carroll Caroline Chang Benetta Chin Kelley Chinen Okimoto Derek Ching Diane L. Ching Michael Ching Darrett Choy

Pattaraporn Chun Claudine Kimura Rachel Coel Tiffany (Tausala) Coleman‐Satterfield Colleen Finnegan Jennifer Concepcion Ashley Cowan Curtis Toma Leo Damasco Dana Lee Joseph D'Angelo Stephen Darling Darrell Natori David (Kawika) Liu David F. Fray Joseph Dela Cruz Peter Di Rocco Leah Dowsett Kathleen Durante Graham Fedorak Brett Ferguson Kristin Fernandez Ryan Flanagan Derek Flores Camilla Fraga Lovejoy Kim Fujinaga Grace Galiza Francisco Garcia

Clinical Instructors Stephanie Abe Chanel Casamina Lee Goerner Laura Hassen Jean Kim Jordan Kono Stefan Mammele Annabelle Mateo

John Mills Kathleen Morimoto‐ Nishioka Brijit Reis Jonathan Rhine Kelsey Rhodes Jodie Toward Jenny Welham

Christopher Gibu

Anna‐Lena Lueker

Nadine Salle

Meri M. Guillou Kristin Hallett R. Michael Hamilton Mathew Harrell Justin Hino Carol Hirai Kelley Hutchins Yomna Ibrahim Susan Ingraham Julie Ireland Irisa Devine Jon Ishii Louise Iwaishi Melanie Jacobson Julie Tullberg Jeffrey Kam Sadie Kim Emmanuel Kling Kevin Kon Kris Baik Douglas Kwock Eugene Lee Jerome Lee Kit Shan Lee Ryan Lee Stephanie Lim Blair Limm‐Chan Felicitas Livaudais Shelley Loui

Amy Lumeng Christopher Lynch Robin Lynch Donna Mah Brent Matsumoto Jennifer Mbuthia Keric Menes John Misailidis Mitchell T. Hamale Dolores Mullikin John Nagamine Gail Nakaichi James K. Nakamura Christopher Naun

Masafumi Sato Vija Sehgal William Sherman Lisa Ann Shigemura Malia Shimokawa James Sim Jonathan Lloyd Sladky Michale Sofer Allyson A. Spence‐ Shishido Brent Tamamoto Terri Tanaka Stephen H. Tenby Carol Titcomb Jeffrey Tom Mari Uehara Stephanie Vann Jasmine Waipa Michael Walter Allan Wang Joseph Ward William Brown Rupa Wong Robert D. II Wotring Brian Wu Melissa Yamauchi David Young Geri Young Lynette Young

Adjunct Professors Catherine Yamauchi Mary Young Yi Zuo

Adjunct Assistant Professors Aimee Grace Katherine Ratliffe

Charles Nguyen Kristyn Nishimoto Norka I. Wilkinson Russell T. Ogawa Michaella Okihara Craig Ono Sarah Park Lucio Pascua Patrice Tim Sing Jonathan Pellett Colin Petko Devin Puapong Josephine Quensell Cherise Saito

Adjunct Instructors Pamela Almeida Kimberly A. Clifton Eydie Nakasone Cheryl L. Griffith Dana K. Ing Leolinda Parlin Erika Pearson Dawn Schaffrick

Tamela Kuhnell Randy Taniguchi Tracie Ann Tjapkes

Hazel Abinsay Valerie Besenbruch Janet Blanchard Judd Boloker Gail Boltron Brenda Camacho Raquel Chan‐Ikeda Lois Chiu Cindy Collo Mark Croley Ty DeSilva Chloe Edinger Tawni Gesteuyala Peter Gregg Robyn Hasegawa Alyssa Honda Trudy Hong Steven Kaplan Megan Kuba Kent Kumashiro Diana Linderoth Kara Morita Mary Rose Nino Irene Papaconstadopoulos Martin Piette Malia Rasa Kristine Robison Paul Ross Krista Schoppy Laura Shumock Lauren Stuart Alyson Tamamoto Courtney Taum Tiong Tjeong Anne Tran Michael Treece

Clinical Educators Akshatha Akshatha Kandie George Richard Jack Kookjae Lee Prashant Purohit Alexandra Ramnath

Department of Pediatrics, 2021 Annual Report

Divisional Reports

Department of Pediatrics, 2021 Annual Report

Division of Community Pediatrics

Gina French, MD Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF COMMUNITY PEDIATRICS

DIVISION MEMBERS Teresa M. Bane-Terakubo, MD

Assistant Professor, Community Pediatrics

Maureen O.J. Chang, MD

Assistant Professor, Community Pediatrics

Benetta Chin, MD Diane Lynne Ching, MD

Assistant Clinical Professor, Community Pediatrics Assistant Clinical Professor, Community Pediatrics

Pia Francisco-Natanauan, MD

Assistant Professor, Adolescent Medicine

Gina M. French, MD Kristen Brooke Hallett, MD Blair Limm-Chan, MD

Associate Professor, Associate Residency Program Director, Division Chief, Community Pediatrics/Developmental/Behavioral Pediatrics Assistant Clinical Professor, Community Pediatrics Assistant Clinical Professor, Community Pediatrics

Joan Meister, MD Kayalvizhi Natarajan, MD

Assistant Professor, Community Pediatrics Assistant Professor, Community Pediatrics

Brenda M. Nishikawa, MD Jeffrey Okamoto, MD

Assistant Professor, Community Pediatrics Assistant Professor, Developmental/Behavioral Pediatrics

Amanda O’Kelly, MD May M. Okihiro, MD

Assistant Professor, Community Pediatrics and Psychiatry

Brittany Raffa, MD Alicia Turlington, MD Mari Uehara, MD Yolanda Wu, MD

Assistant Professor, Community Pediatrics/Hawaii Initiative for Childhood Obesity Research and Education Assistant Clinical Professor, Community Pediatrics Assistant Clinical Professor, Community Pediatrics Assistant Clinical Professor, Community Pediatrics/Developmental/Behavioral Pediatrics Assistant Professor, Community Pediatrics

Yolanda Wu, tech advisor Selina Chen, Teresa Bane Terakubo, Brenda Nishikawa, Gina French, Blair Limm-Chan, Kelsey Rhodes, Benetta Chen, Brooke Hallett, Maureen Chang, Joan Meister, Brittany Raffa, Jeffrey Okamoto, May Okihiro, Mari Uehara, Pia Francisco-Natanuan, Not pictured Diane Ching.

Department of Pediatrics, 2021 Annual Report

DIVISION OF COMMUNITY PEDIATRICS DIVISION OVERVIEW

he Community Pediatrics Division is a team of general pediatricians, ambulatory pediatric subspecialists, researchers, and family advocates who are engaged in a variety of academic and direct service activities that support a common philosophy that pediatrics must aim to treat children as human beings and consider the full context of their lives—their families, communities, cultures, and personal stories. The philosophy is promoted by engaging in clinical care in a variety of hospital and community settings; by training others about the practical application of community pediatrics; by advocating for policies and practices that will weave these values into the health care system; and by conducting research to develop new ideas and to improve practices. The need for community pediatrics is especially pronounced when looking at underserved and vulnerable children. Therefore, the Division places special emphasis on programs and initiatives that will improve care for these populations.

CLINICAL ACTIVITIES The Division’s clinical activities include the general and subspecialty care of children and families in the Kapi‘olani Medical Center for Women & Children (KMCWC) newborn nursery, Kapi‘olani Medical Specialists Clinics, Pediatric Outpatient Clinical and Kapi‘olani Child Protection Center, and at the Queen Emma Clinics, Kokua Kalihi Valley Comprehensive Family Services, Family Court’s Detention Center, and the Hawai‘i Youth Correctional Facility. Division members care for about 70% of newborns delivered at KMCWC (roughly 2,500- 3,000 infants/ year). Each year, about 12,000 children visit the Pediatric Outpatient Clinic for acute and Well Child Care. Division members also provide ambulatory pediatric services at the Queen Emma Clinic and Kokua Kalihi Valley Health Center. In addition, the Division provides subspecialty services in developmental and behavioral pediatrics, adolescent medicine, child physical and sexual abuse, and pediatric consultative care for children hospitalized at Shriners Hospital and general pediatric expertise for Kpi‘olani’s multidisciplinary clinics including obesity treatment and craniofacial clinic.

HAWAII INSTITUTE FOR CHILDHOOD OBESITY RESEARCH AND EDUCATION (HICORE) HICORE was developed in 2008, through generous funding from the Hawai‘i Medical Service Association (HMSA) Foundation, to provide leadership for a collaborative, multi-disciplinary effort in research and education on childhood and adolescent obesity in Hawai‘i. The goals of HICORE are: 1) to serve as a repository of childhood and adolescent obesity research projects conducted in Hawai‘i; 2) to provide guidance to granting agencies and foundations regarding research priorities in the area of childhood and adolescent obesity for the state of Hawai‘i; 3) to serve as a center for the education of community members, medical students, residents, physicians, and others in the area of childhood and adolescent obesity in Hawai‘i; and 4) to conduct research on childhood and adolescent obesity relevant to people of Hawai‘i. HICORE is collaborating with the Department of Health Healthy Hawai‘i Initiative to provide a CME seminar on early childhood prevention to pediatric providers at community health centers.. Although the current grant for HICORE has run out, Dr. May Okihiro directs activities associated with the program. For more information, please go to: http://www.hawaii5210.com

2020-2021 HIGHLIGHTS We’ve been focusing on the same issue as everyone else in medicine for much of this year. In addition to our usual clinical work, we provide care for sick patients of many of the children of the pediatricians in the community who do not feel equipped to do so.

Division Chief, Gina M. French, MD is also Associate Program Director of the Pediatric Residency and the Medical Director of the Pediatric Outpatient Clinic at KMCWC and has a Pediatric Behavioral Clinic in the Pediatric Clinic that focuses on children with challenging behavioral conditions. She is the chair of the Newborn Standards of Excellence Committee, serves on the EPIC Pediatric Committee and is chair of the Physician Assistance Committee.

MEDICAL EDUCATION, ADVOCACY & RESEARCH The Community Pediatrics Division is responsible for medical student, resident, nurse practitioner, and premedical education for the University of Hawai‘i Pediatric Residency Program’s (UHPRP) Continuity of Care Primary Care Program.

Department of Pediatrics, 2021 Annual Report

DIVISION OF COMMUNITY PEDIATRICS Teresa Bane-Terakubo, MD is the medical director at the Queen’s Medical Center Pediatric Clinic an is responsible for the continuity curriculum there. She also works at the pediatric clinic at Kapi‘olani Medical Center for Women & Children. Benetta Chin, MD joined us in the spring, moving from Canada. She is trained in emergency medicine with a strong interest in coordinated with mental health services.

Brenda M. Nishikawa, MD in addition to her excellent care to a panel of medically fragile children at the clinic, coordinates the ambulatory pediatrics rotation. The rotation provides pediatric residents with a rich immersion experience in provision of care in the outpatient setting at Kapi‘olani Pediatric Outpatient in addition to exposing them to a wide array of services community services for children. There are several highly esteemed pediatricians in the community who decided to become pediatricians after meeting and working with Dr. Nishikawa. She has received the medical student outpatient teaching award.

Maureen Chang, MD coordinates the Reach Out and Read program for Jeffrey K. Okamoto, MD is now full time in clinical developmental and the Pediatric Outpatient Clinic. This program is an evidence based behavioral pediatrics at KMCWC. He is on the Council Management literacy improvement program that provides free books and anticipatory guidance on reading to children to the families in our clinic. Committee for the national American Academy of Pediatrics (AAP) and is the incoming Vice-President for the Hawai‘i chapter of the AAP. Diane Lynne Ching, MD was awarded the teaching award by the 3rd year medical students for her excellent teaching in the nursery and works for the children in the craniofacial clinic.

May M. Okihiro, MD is continuing to study the development of metabolic syndrome in Native Hawaiian and Samoan youth (funded by the NIH/NCMHD and JABSOM Department of Native Hawaiian Health’s Center for Native and Pacific Health Disparities. She published with her Kristen “Brooke” Hallett, MD has been managing the online curriculum colleagues at Waianae Coast Comprehensive Health Center in the for the continuity clinics. Hawai‘i Medical Journal this year. Pia Francisco-Natanauan, MD provides clinical care to incarcerated youth at the Detention Center and the Hawai‘i Youth Correctional Facility. In addition she provides consultative services to adolescents in the specialty center at Kapi‘olani Medical Center for Women & Children. She has particular interest in eating disorders and contraceptive care. Blair Limm-Chan, MD Joined us in the fall. In addition to having a baby girl, she has been helping us with our clinic patients with renal conditions as she is trained as nephrologist.

Alicia Turlington, MD provides pediatric care and training at Kalihi Kokua Valley Community Health Center. The Center has a unique program providing legal services for families obtaining care at the pediatric clinic. Dr. Turlington’s particular interest is in providing integrated community based care for families living with the multiple burdens of poverty and inequity. She has provided innovative group well care at KKV.

Yolanda Wu, MD has been serving in an administrative role, managing the schedule and morale in addition to her clinical work in the clinic and Joan Meister, MD provides leadership in the Craniofacial Clinic and is at Shriner’s. She has been providing community service as room mother renowned for her teaching in the nursery. She has received the medical to two classrooms in two schools is the assistant cubmaster in charge of student teaching award and resident teaching award in addition to the activities and recently completed the Wood Badge. general consensus that “Joan is great”. Kayalvizhi Natarajan, MD teaches in the continuity clinic at Queen’s Medical Center and provides services to sexually and physical abused children through the Kapi‘olani Center for the Protection of Children and Sexual Abuse Treatment Center.

Department of Pediatrics, 2021 Annual Report

Division of Neonatal-Perinatal Medicine Charles Neal, MD Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF NEONATAL-PERINATAL MEDICINE

DIVISION MEMBERS NEONATOLOGISTS: Akshatha, MD Kenneth M. Ash, MD Venkataraman Balaraman, MBBS Pattaraporn Chun, MD Megan Doty, MD Kandie George, MD Christopher Gibu, MD Carol Hirai, MD Lynn M. Iwamoto, MD Richard Jack, MD Melanie Jacobson, MD Emmanuel Kling, MD Sheree Kuo, MD Charles R. Neal, MD, PhD Alexandra Ramnath, MD Kara Wong Ramsey, MD Sneha L. Sood, MD Cherilyn Yee, MD NEONATAL HOSPITALISTS: Stephanie Abe, MD Ashley Cowan, MD Jean Kim, MD Sadie Kim, MD Kent Kumashiro, MD Jerome Lee, MD Kit Shan Lee, MD Annabelle Mateo, MD John Mills, MD Camnhung Nguyen, MD Alyson Tamamoto, MD Jasmine Waipa, MD Jim Mueggenberg, MD NEONATAL NURSE PRACTITIONERS: Pamela Almeida, NNP Janet Blanchard, NNP Kimberly Cliffton, NNP Cheryl Griffith, NNP Dana Ing, NNP Tamela Kuhnell, NNP Jaymie Pinho, NNP Kristine Robison, NNP Dawn Schaffrick, NNP Laura Shumock, NNP Randy Taniguchi, NNP Maria Tereza Untanu, NNP

Clinical Educator Associate Clinical Professor of Pediatrics Associate Professor of Pediatrics and Vice Chair Assistant Clinical Professor of Pediatrics Assistant Professor of Pediatrics Clinical Educator Assistant Clinical Professor of Pediatrics Assistant Clinical Professor of Pediatrics Associate Professor of Pediatrics Clinical Educator Assistant Clinical Professor of Pediatrics Assistant Clinical Professor of Pediatrics Associate Professor of Pediatrics Professor of Pediatrics, Division Chief and Medical Director Assistant Clinical Professor Assistant Professor of Pediatrics Assistant Professor of Pediatrics Assistant Professor of Pediatrics Clinical Instructor Assistant Clinical Professor Clinical Instructor Assistant Clinical Professor Clinical Educator Assistant Clinical Professor Assistant Clinical Professor Clinical Instructor Clinical Instructor Assistant Clinical Professor Clinical Educator Assistant Clinical Professor

Adjunct Inctructor Clinical Educator Adjunct Instructor Adjunct Instructor Adjunct Instructor Clinical Educator Adjunct Instructor Clinical Educator Adjunct Instructor

Department of Pediatrics, 2021 Annual Report

DIVISION OF NEONATAL-PERINATAL MEDICINE DIVISION OVERVIEW

ur Neonatal Intensive Care Unit (NICU) consist of 70 single family rooms, with a capacity of 84 beds. Due to poorly understood effects of COVID on low birth weight and overall deliveries in Hawai‘i and elsewhere in the United States, we did see a downward trend in census last year. There were 984 admissions to the NICU (down from 1092 one year ago). The average daily census in the NICU was 66 (down from 74 one year ago). Of these admissions, 142 were very low birth weight (down from 175 last year). The neonatology division maintains a very close working relation with the Maternal Fetal Medicine group. Weekly conferences are held with the neonatologists, maternal fetal medicine specialists and their fellows. The NICU measures its outcomes using the Vermont Oxford Network (VON) database. VON is the largest NICU database in the United States and Kapi’olani benchmarks itself to Type C units with similar risk profiles. In spite of high census and acuity in its clinical services, our NICU consistently ranks above the top quartile on all of its major VON measures, including very low birth weight (VLBW) overall morbidity, NEC, nosocomial infection, overall mortality and human milk intake at discharge. In addition to 24-hour in-house coverage in the NICU and Labor & Delivery at Kapi’olani Medical Center for Women & Children, the division also provides 24-hour consultation coverage for Level II neonatal services in Labor and Delivery and the Newborn Nursery at Queen’s Medical Center. We also provide telephone advice to Pediatricians on our neighbor islands and the Pacific Rim. To further our outreach with local and neighbor island providers, our group has traveled to provide in-person neonatal resuscitation training. During COVID, we are expanding our outreach by using on-line conferencing platforms for education. Neonatal Transport Services remain very active. The Kapi’olani transport team participated in 206 neonatal transports. Of these, 146 neighbor island transports came to Kapi’olani and 33 were taken to Kaiser Hospital. There were 42 transports from Oahu facilities to Kapi’olani. There were 18 outgoing neonatal transports, including 12 to the mainland and 6 to Straub Hospital for cardiac catheterizations. In addition, the division provides ongoing supervision and training for our highly qualified transport nurses and respiratory therapists.

assessment to the high-risk infants who are at risk for growth failure and developmental delays due to prematurity, low birth weight, and complex medical problems during the newborn period. Due to the COVID pandemic, there was an implementation of Telehealth platform for the first time this past year, at which we provided total of 102 encounters through Telehealth visits.

NICU NEURODEVELOPMENTAL FOLLOW-UP CLINIC In addition to the NICU Medical Follow-up Clinic, we also monitor developmental milestones of high-risk infants up to 2 years old through the NICU Neurodevelopmental Follow-up Clinic, where we provide serial developmental assessments. In partnership with Rehabilitation Services, and Jaymie Pinho, NNP, there were 190 visits seen at this Neurodevelopmental Follow-up Clinic last year (increased from 90 in the previous year). We also have a strong collaboration with Dr. Mari Uehara of Developmental Behavioral Pediatrics in caring for these infants with developmental delays. The current Director for both NICU Medical and Neurodevelopmental Follow-up Clinic is Dr. Pattaraporn Chun.

PULMONARY HYPERTENSION TEAM The Pulmonary Hypertension (PH) Team is a multidisciplinary collaboration between Neonatology, Pediatric Critical Care, Pediatric Cardiology and Pediatric Pulmonology, formed in 2016. Dr. Sheree Kuo played a lead role in development and evolution of this team and she remains an active leader in the group. The PH team, on average, follows 30-40 in-patient and out-patient newborns and children, the majority being former premature infants with bronchopulmonary dysplasia. After discharge, infants with ongoing PH are followed in the interdisciplinary Pediatric Pulmonary Hypertension Clinic. In this clinic, patients are seen by intensivists (either neonatology or pediatric critical care), a pediatric cardiologist and a pediatric pulmonologist. Additional ancillary services available in PH clinic include dietary counseling, physical and occupational therapy and speech therapy.

There were 338 visits, with 229 patients seen at the NICU Medical Follow-up Clinic last year (increased from 230 in the previous year). This follow-up clinic provides outpatient care that encourages development of high-risk infants, including the assessment and monitoring of growth and nutritional needs, as well as management of the ongoing medical issues after hospital discharge. We provide clinical management, care coordination with multidisciplinary and interprofessional care teams. We also offer a developmental

Department of Pediatrics, 2021 Annual Report

DIVISION OF NEONATAL-PERINATAL MEDICINE risk children. With a very narrow time window for enrollment and the height of the pandemic, although we screened some eligible patients, The Hanuola ECMO program at KMCWC is the only pediatric we were unable to enroll any participants into the active protocol. This extracorporeal life support program in Hawai‘i. Drs. Len Tanaka, Sheree research study is now closed for accrual. In the coming academic year, Kuo and Jaime Harrington serve as Medical Director and Associate we will be actively recruiting patients on two national studies, POPS 2 Medical Directors for Hanuola. The program is a cooperative and ICAF. POPS-2 is an opportunistic study of Drug Pharmacokinetics in collaboration between Neonatology, Pediatric Critical Care and Pediatric specific pediatric populations coordinated through the Duke Clinical Surgery. In addition to Dr. Kuo, Drs. Megan Doty, Christopher Gibu, Research Institute. ICAF is a study of extended administration of Richard Jack, Charles Neal and Alex Ramnath are ECMO certified caffeine in babies born prior to 30 weeks’ gestation and its impact on physicians, helping to provide 24/7 consultation and treatment services neurodevelopment and decreasing episodes of Intermittent Hypoxia. Dr. in the NICU. There were two Neonatal ECMO run last year in a critically Megan Doty is a Co-investigator on POPS-2 study while Drs. Alexandra ill newborn. In 2020, Hanuola was awarded the ELSO Center of Ramnath and Charles Neal are co-investigators on the ICAF study. Excellence in Life Support, a Gold Level designation. The second phase of NOVI (Neurobehavioral Outcomes of Very Preterm Infants), known as NOVI-ECHO, is an NIH funded extension of FELLOWSHIP PROGRAM the multi-center NOVI study of neonates born at <30 weeks’ gestation. The purpose of ECHO (Environmental Influences of Child Health Our accredited joint fellowship program with Tripler Army Outcomes) in the NOVI cohort is to assess home and environmental Medical Center is one of three military neonatology fellowships in the influences on early neurobehavioral development using several country. There is one fellow in our program in 2020-2021: Dr Lauren cognitive and Neuromotor assessments at 5, 6 and 7 years of age. The Staiger. Weekly fellow conferences are conducted which cover case primary investigator of this study is Dr. Charles Neal. Last year 4 studies, morbidity and mortality, basic science topics, clinical journal manuscripts were published and currently one is in press and four are critiques and quality improvement. We continue to participate in the under review. The Hawai’i IDeA Center for Pediatric and Adolescent Western Interstate Fellows QI Tele-Conference, which includes five Clinical Trials (HIPACT) is an NIH funded multicenter clinical trials grant, neonatal fellowship programs with Dr Lynn Iwamoto as Site Director. funded under the ECHO umbrella. In the past year, the HIPACT group This coming academic year Dr. Laura Borruso will join our fellowship has initiated a Neonatal Opioid Withdrawal Syndrome (NOWS) study in program as a trainee. There are no civilian fellows in this program. the NICU, a randomized study of two treatment protocols. Our ACTNOWS study group is presently in the second phase of randomization RESEARCH and recruitment is on-going. The HIPACT Pre-Peri-Postnatal Several members of the Neonatology Division are involved in a Subcommittee chair for this study is Dr. Charles Neal. Drs. Akshatha variety of research projects. These include pharmaceutical sponsored and Wong-Ramsey are co-investigators in the NOWS study. trials, clinical studies and quality improvement projects. The division Our Neonatal-Perinatal fellow Dr. Lauren Staiger is working on continues to participate with faculty support at the annual HPH Summer Body Composition in Infants of Diabetic Mother. Drs. Sheree Kuo and Student Research Program. Kara Wong-Ramsey are Co-PIs. Drs. Kuo and Wong-Ramsey are also The Optimist trial, which closed for enrollment in 2020, working on a 3D body scanning of infant body composition in targeted neonates born between 25 and 28 weeks’ gestation who are collaboration with Dr. John Shepherd at the UH Cancer Research Center. less than 6 hours of age and failing non-invasive ventilation due to RDS. Enrolled patients were given surfactant via a small-bore catheter while spontaneously breathing on non-invasive respiratory support. A total of 486 infants where enrolled and randomized. The manuscript is being revised for publication. The site primary investigator of this study is Dr. Sheree Kuo.

HANUOLA ECMO PROGRAM

Pharma supported clinical research in the division included, The Medimmune RSV Vaccine Study is a phase 2/3 randomized, doubleblind, palivizumab-controlled study to evaluate the safety of MEDI8897, a Monoclonal Antibody with an Extended Half-life against RSV, in high-

Department of Pediatrics, 2021 Annual Report

DIVISION OF NEONATAL-PERINATAL MEDICINE HOSPITAL AND UNIVERSITY SERVICES Each division member remains active in Hospital and Pediatric Department Committees, as well as all levels of medical school and resident education. Dr. Megan Doty is the NICU Rotation Director for the University of Hawai’i Pediatric Residency Program. Dr. Kara Wong Ramsey and Dr Akshatha are research advisors on the Pediatrics Residency Program Resident Research Committee. Dr Kara Wong Ramsey is the MS3 NICU Rotation Director for JABSOM Pediatrics and she is on the JABSOM pediatric medical student committee and a faculty advisor on the medical student pediatric interest group. Dr. Sheree Kuo is the course director for Pediatrics 545F, the 4th year medical student NICU clerkship for JABSOM Pediatrics. Several members of the division are also active in hospital and department leadership. Dr. Venkataraman Balaraman is Vice-Chair for Clinical Affairs in Pediatrics. Dr. Charles Neal is Division Head for Neonatology and maintains his role as Medical Director for the NICU. Dr. Lynn Iwamoto remains the head of QI for the Department of Pediatrics. She is also co-rotation director for the pediatric resident QI/PS rotation and faculty advisor for the medical student interest group for PSQI. This interest in quality and patient safety education is complemented by her roles as the co-chair of the NICU Standards of Excellence committee for quality and patient safety and chair of the KMCWC ABP Maintenance of certification sponsor portfolio. Within the University, she also serves on the Dept of Pediatrics CME and JABSOM Academic Appeals Committees. Dr. Sheree Kuo is Medical Director of Neonatal Transport services. Dr. Richard Jack is the Associate Medical Director of Neonatal Transport. Dr. Kuo is also Associate Director of the Hanuola ECMO program. She is also on the Dept of Peds Personnel Committee. She is the Chair, AAP District VIII Section on Neonatal –Perinatal Medicine and Board Member, Hawai’i Mothers’ Milk, Inc. Drs. Sneha Sood & Kara Wong Ramsey are coMedical Directors of the Special Care Newborn Nursery at Queens Medical Center. Dr Pat Chun is the Director of the NICU and Neurodevelopmental Clinic. Dr. Chris Gibu is on the Code Blue Committee, RAD/POCUS Committee, RESUS Committee and Golden Hour Committee. Dr. Alex Ramnath is also on the Code Blue Committee and the Perinatal Working Group Committee. Dr. Sneha Sood, with assistance of Dr. Emmanuel Kling, is the neighbor island liaison working on neonatal resuscitation training; they both are also active members of the IEU Committee for the Pediatric Residency. Dr. Kling is on the Departmental Communication Committee. Dr. Kandie George is our current Palliative Care NICU Liaison representing on the NICU Bereavement Committee and the hospital wide Palliative Care & Bereavement Committee. Dr. George has played a key role in the development of team consults for periviable deliveries. She also assisted in developing a comfort care order set, as well as admission and

discharge note templates for physicians, to ease their workflow for a dying baby. Several members of the division are on the University of Hawai’i Pediatric Residency Program interview and selection committee: Dr. Ashley Cowan, Dr. Kandie George, Dr. Emmanuel Kling, Dr. Sheree Kuo, Dr. Sneha Sood and Dr. Kara Wong Ramsey This coming academic year Misty Smith, a neonatal nurse practitioner, will be joining our group. Despite the challenges we face during the COVID pandemic, the division remains highly dedicated to meeting our mission of providing the highest quality clinical care, education, research and community service, while also striving for a safe healthy environment during the pandemic – with zero exposure and zero infections this past academic year and a 97.6% vaccination rate for the division.

Correspondence may be sent to: Charles R. Neal, MD, PhD Professor of Pediatrics and Neonatology Division Director University of Hawaii John A. Burns School of Medicine Neonatology Clinical Section Chief Kapiolani Medical Specialists Medical Director, Newborn Intensive Care Unit

Kapiolani Medical Center for Women & Children 1319 Punahou St. Honolulu, Hawaii 96826 Office: (808) 983-8670 Fax: (808) 983-6392 cneal@hphmg.org

Department of Pediatrics, 2021 Annual Report

Division of Pediatric Emergency Medicine Paul Eakin, MD Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC EMERGENCY MEDICINE

DIVISION MEMBERS T. Tausala Coleman-Satterfield, MD

Assistant Professor of Pediatrics

Peter J. Di Rocco, MD

Assistant Professor of Pediatrics

Paul J. Eakin, MD

Associate Professor of Pediatrics

Francisco J. Garcia, MD

Assistant Professor of Pediatrics

Travis K.F. Hong, MD

Assistant Professor of Pediatrics

Alson S. Inaba, MD

Associate Professor of Pediatrics

Jannet J. Lee-Jayaram, MD

Assistant Professor of Pediatrics

Masafumi Sato, MD

Assistant Professor of Pediatrics

Loren G. Yamamoto, MD, MPH, MBA

Professor of Pediatrics

Lynette L. Young, MD

Assistant Professor of Pediatrics

he Pediatric Emergency Medicine Division is responsible for: around the clock medical care for pediatric patients with urgent and emergent conditions, pediatric hospital sedation, quality improvement, administration, nursing education, medical student and resident education, and pre-hospital (EMS) education.

University of Hawai‘i John A. Burns School of Medicine / Kapi‘olani Medical Center Contributions: Problem Based Learning (PBL) tutoring, ward attending, Grand Rounds, Pediatric Resident conferences, student preceptoring, student exams, research, continuing medical education, contribution to educational and life support programs sponsored by the American Academy of Pediatrics (AAP), the American College of Emergency Physicians (ACEP), and the American Heart Association (AHA). The Emergency Medicine Division contributes to the Academy of Pediatrics, the American College of Emergency Physicians, and the American Heart Association. The Division also contributes substantial faculty resources towards medical student and resident education and has been recognized for teaching excellence on multiple occasions.

The PEM division is responsible for scheduling 24/7 attending pediatric physician coverage for the pediatric emergency medical service, utilizing PEM Fellowship trained / Board certified Pediatric Emergency Physicians who care for over 30,000 pediatric patients annually. They also provide 24-hour Pediatric Code Blue coverage for KMCWC.

This division collectively has published countless research papers, chapters, received numerous awards and accomplishments in medical education, academic research, and community service. Since 2014, The PEM group has been employed by US Acute Care Solutions, the largest physician owned emergency medicine group in the country, headquartered in Canton, Ohio (usacs.com).

Department of Pediatrics, 2021 Annual Report

Division of Pediatric Hematology and Oncology Randal Wada, MD Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC HEMATOLOGY AND ONCOLOGY

DIVISION MEMBERS Darryl Glaser, MD

Assistant Professor of Pediatrics

Kelley Chinen Okimoto, MD

Assistant Clinical Professor of Pediatrics

Kelley Hutchins, DO, MPH

Assistant Clinical Professor of Pediatrics

Jasmin Jensen, MD

Assistant Professor of Pediatrics

Wade Kyono, MD

Assistant Professor of Pediatrics

Stephanie S. Lim, MD

Assistant Clinical Professor of Pediatrics

Desiree Medeiros, MD

Assistant Professor of Pediatrics

Randal Wada, MD

Associate Professor of Pediatrics, Division Chief

Robert Wilkinson, MD

Professor of Pediatrics

SPECIALTY CLINICS

he Division staff a number of specialty clinics that are available to Hawai‘i’s children and adolescents. These include the Hemophilia and Thrombosis Treatment Center of Hawaii, Coagulopathy Clinic, Bone Marrow Transplant Clinic, Complex Vascular Anomalies Clinic, Long-Term Follow- up (LTFU) Clinic for survivors of childhood cancer, and an Adolescent and Young Adult LTFU clinic. There are several neighbor island Hemophilia Outreach clinics.

RESEARCH Division members actively participate in clinical and basic research in oncology and hematology. Bench and translational research is conducted by Stephanie S. Lim, MD in laboratories at the University of Hawaii Cancer Research Center. Clinical research is ongoing through involvement with the Children’s Oncology Group, Blood and Marrow Transplant Clinical Trials Network, Beat Childhood Cancer Consortium, Pediatric Blood and Marrow Transplant Consortium, the Center for Health Outcomes, and JABSOM. Health behavior research is also conducted through the SONDH.

PROFESSIONAL AND UNIVERSITY SERVICE Darryl Glaser, MD serves as Medical Director for Hematology/Oncology, and is a member of the hospital’s Cancer Committee. Kelley Hutchins, DO, MPH serves as Medical Director for the Adolescent and Young Adult Long Term Follow Up Clinic. Jasmin Jensen, MD is the Medical Director of Navian Hawai‘i’s Pediatric Hospice team, Hawai’i Pacific Health’s Apheresis program, and the Multi-disciplinary Complex Vascular Anomalies Clinic. In addition to his work with COG and the Hawai’i Pacific Health Research Institute, Wade Kyono, MD is a member the University of Hawai‘i Cancer Center’s Minority Underserved-NCI ommunity Oncology Research Program (UHCC MU- NCORP), and is the Vice Chair of the COG NCORP Committee. Desiree Medeiros, MD is Medical Director of the Hemophilia and Thrombosis Treatment Center of Hawai‘i, and a member of the Western States Regional Coordinating Committee. She also serves on the hospital’s Blood Utilization Committee and Pharmacy and Therapeutics Committee. Randal Wada, MD is a Professor in the Departments of Pediatrics and Nursing with JABSOM and SONDH. He is director of the Pediatric Hematopoietic Progenitor Cell Transplantation program at the Kapi‘olani Children’s Blood and Cancer Center, and serves as the Medical Director of the Hawaii Bone Marrow Donor Registry and the Hawai‘i Cord Blood Bank. Robert Wilkinson, MD retired from clinical practice in January of 2016 after 42 years of serving the community. He continues to maintain his faculty position and his membership in COG, and remains active in teaching medical students and residents.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC HEMATOLOGY AND ONCOLOGY ACCOMPLISHMENTS AND FUTURE GOALS Future plans include developing an extra-corporeal photopheresis service within the Apheresis Program, as well as point of care ultrasound for the Hemophilia and Thrombosis Treatment Center. We will continue to provide compassionate, state-of-the- art pediatric cancer care to the children of Hawai‘i and the Pacific Islands through participation in cooperative group clinical trials, to advance hematology and oncology research in the State of Hawai‘i, and excel in teaching medical students and residents through the University of Hawai‘i John A. Burns School of Medicine.

Robert Wilkinson

Kelley Chinen Okimoto

From top left: Desiree Medeiros, Stephanie Si Lim, Kelley Hutchins, Darryl Glaser, Wade Kyono, Jasmin Jensen, Robert Wilkinson, Randal Wada, Kelley Chinen Okimoto

Department of Pediatrics, 2021 Annual Report

Division of Pediatric Hospitalist Medicine Jessica Kosut, MD Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC HOSPITALIST MEDICINE

DIVISION MEMBERS Selina S.P. Chen, MD, MPH

Assistant Professor of Pediatrics

Diane P. Ching, MD

Assistant Professor of Pediatrics

Jennifer Di Rocco, DO, Med

Assistant Professor of Pediatrics

Marissa Fakaosita, MD

Assistant Professor of Pediatrics

Tyler Klein, NP

Pediatric Nurse Practitioner

Jordan Kono, MD

Assistant Clinical Professor of Pediatrics

Jessica S. Kosut, MD

Assistant Professor of Pediatrics and Division Chief

Mae Kyono, MD

Assistant Professor of Pediatrics

Kyra A. Len, MD

Associate Professor of Pediatrics

James C. Lin, MD

Assistant Professor of Pediatrics

Anna-Lena Lueker, MD

Assistant Professor of Pediatrics

Maya Maxym, MD

Assistant Professor of Pediatrics

Barry M. Mizuo, MD

Assistant Professor of Pediatrics

Cheryl Okado, MD

Assistant Professor of Pediatrics

Shilpa Patel, MD

Associate Professor of Pediatrics

Gina Ramirez, MD

Assistant Professor of Pediatrics

William P. Shea, MD, MA

Assistant Professor of Pediatrics

Tiffany Wang, MD

Assistant Professor of Pediatrics

DIVISION OVERVIEW

he Division of Pediatric Hospitalist Medicine has grown over the past 15 years and now is a division of 18 hospitalists and 1 pediatric nurse practitioner. Two years ago, the American Board of Pediatrics granted Pediatric Hospital Medicine subspecialty board status and our division has already had members sit for and pass this examination with more slated to take the exam next year. Given the effects of the global pandemic, this past year brought new challenges to the division. In an effort to maintain safety for our learners and our patients and families, while continuing to offer the highest level learning for our students and residents, we had to make adjustments to our family-centered rounds. Through the utilization of a telehealth platform we conducted family centered rounds such that residents and students were able to participate both in-person and remotely, families were involved in rounds even when visitor restrictions were in place, and interpreters were afforded the opportunity to provide realtime translation without coming in to the medical center. This innovation also reduced the use of precious PPE.1 And while caring for patients in the midst of the pandemic, division members continued to innovate in areas of teaching, quality improvement, and public health, while still remaining active on the various committees and activities of the hospital and the hospital system.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC HOSPITALIST MEDICINE TEACHING AND EDUCATION

students, helping them gear up for their new supervisory roles.

Dr. Jennifer Di Rocco has been involved on the national level in the development of the pediatric milestones utilized to evaluate pediatric residents during their training and to identify their progress along a continuum in various aspects of their training. This year she and the national workgroup were able to publish the second version of the Pediatric Milestones. She has been able to share this work at the American Pediatric Program Directors Association National Meeting and locally at Tripler Medical Center.2

Pediatric Hospitalists remain actively involved in the medical school as well, serving as advisors for the Pediatric Interest Group, in their roles as Longitudinal Clinical Mentors and as third year clerkship preceptors.

Drs. Fakaosita and Di Rocco also published an article in the American Academy of Pediatrics News about the different experience of this past year’s virtual residency recruitment season. They described the effects of the pandemic on medical students with many being pulled from rotations and some being unable to experience core rotations inperson and the effects this will have on this year’s entering intern class.3

Drs. Cheryl Okado and Jordan Kono presented Grand Rounds on Updates in Pediatric Hospital Medicine over the past year and shared important articles that were published over the last year and will impact how certain disease processes are managed.

QUALITY IMPROVEMENT

Annually, hospitalists participate in the Hawaii Pacific Health Summer Student Research Program, where over the course of a summer, physicians mentor students in the execution of a research project from Drs. Barry Mizuo and Kyra Len were both instrumental in developing a research question development to data collection to statistical analysis case-based curriculum for the medical students during their clerkship of the data. Finally the work is presented to the Hawaii Pacific Health to ensure a robust educational experience, given the limitations of Community. From the hospitalist division, Drs. Marissa Fakaosita, students coming to the medical center during the pandemic. This Jessica Kosut, and Barry Mizuo participated. Dr. Mizuo’s project curriculum, which allows for virtual cases, was well-received by the centered around the utilization of procalcitonin to decrease antibiotic students with very positive comments. use in pediatric patients admitted for pneumonia, while Drs. Fakaosita As students returned to the wards, Dr. Mizuo oversaw changes to the and Kosut studied the potential of safely administering heated high flow oxygen to infants with bronchiolitis on the pediatric ward versus hospitalist lectures given to medical students 3 times per week. Drs. Mizuo and Len, as well as Dr. Diane Ching developed interactive, case- in the pediatric intensive care unit. Drs. Fakaosita and Kosut have continued their work with bronchiolitis by participating in the national based lectures that each hospitalist can give and allows for a more Value in Inpatient Pediatrics (VIP) Network study HIFLO- High Flow uniform curriculum with the coverage of core topics for the students. Interventions to Facilitate Less Overuse of high flow oxygen Dr. Marissa Fakaosita continues in her role as director of the administration in the care of infants with bronchiolitis. innovative Individual Educational Unit that allows residents to tailor their residency education to create experiences that will best prepare Drs. Jordan Kono and Jennifer Di Rocco oversee journal club and case them for their eventual career goals. This ranges from neighbor island review forum for the hospitalist group and led several multidisciplinary case review forums with several subspecialists in rotations, subspecialty rotations, rotations at outside institutions, as attendance. These monthly sessions allow for interactive discussions well as opportunities for research, community service, and advocacy. This continues to be a highlight of the residency program and one that amongst the hospitalists as well as continued education and refinement of our clinical practice and practice guidelines. draws prospective residents to our program.

Dr. Tiffany Wang, who has been the resident ward rotation for the last several years, was joined in the position by Dr. Gina Ramirez. They continue to examine the ward experience for residents, adjusting schedules and roles to allow for a varied clinical experience, while ensuring they work within the duty-hour restrictions. Given the reduced clinical exposure during the pandemic, the second year residents now have an added 2 week block on the wards where they function without a junior resident and work directly with medical

Drs. Anna Lueker and Maya Maxym continue to lead Pediatric ECHO, a bimonthly lecture series, about topics of interest for pediatricians, ranging from infectious diseases and COVID to physiatry to infant mental health to the return of children to school during the pandemic.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC HOSPITALIST MEDICINE PUBLIC HEALTH

COMMITTEE WORK

Dr. Shilpa Patel led the efforts of Hawaii Pacific Health’s Pier 2 COVID 19 mass vaccination site, the first mass vaccination center in the state. Several hospitalists volunteered at Pier 2 including Marissa Fakaosita, Mae Kyono, Jessica Kosut, Selina Chen, and Tyler Jansen. Additionally, Drs. James Lin and Selina Chen provided critical IT infrastructure support for this endeavor. This effort allowed for more than 184,000 vaccines to be administered.4

Dr. Mae Kyono is vice-chair of the hospital Department of Pediatrics and is a member of MEC. Dr. Tiffany Wang took over as Chair of the Pediatric Standards of Excellence Committee and has already begun examining policies surrounding co-management and around patients needing to leave the medical center for procedures while admitted. And finally, Dr. Jessica Kosut began her role as Chair of Quality Council.

The hospitalist group also felt compelled with the issues of the pandemic to speak up and share our views with the local community. AWARDS Dr. Maya Maxym published a letter to the editor of the Star Advertiser At this year’s Pediatric Resident Dinner, Dr. Marissa Fakaosita was entitled, “We all have a big stake in delivery COVID-19 vaccines to the awarded the Medical Student Faculty Award, while the Resident world.” Similarly, Dr. Jennifer Di Rocco wrote a letter to the editor Faculty Ao’o award was given to Dr. Jessica Kosut. about the effects of distance learning on our keiki, while Dr. Jessica Kosut wrote a letter to the editor encouraging the return of our keiki back to school given all of the services and social interactions that children miss out on. Finally, Drs. Marissa Fakaosita and Maya Maxym created the Department Diversity, Equity, and Inclusion Work-group to strategize ways in which to educate ourselves and our learners about how to recognize and combat implicit bias, understand the effects of racism on our patients’ well-being and clinical outcome and to incorporate ethnic disparities awareness and principles of equity in our clinical practice, research and advocacy work.

From top left: Shilpa Patel, Jessica Kosut, Marissa Fakaosita, Maya Maxym, Tyler Jansen, Tiffany Wang, Kyra Len, Barry Mizuo, Jordan Kono, Jennifer Di Rocco, Gina Ramirez, Selina Chen, Diane P. Ching, Mae Kyono, Cheryl Okado, Adrianna Herrera

Department of Pediatrics, 2021 Annual Report

Division of Pediatric Intensive Care John J. Harrington, III, MD Division Chief

Rupert K.S. Chang, MD Medical Director

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC INTENSIVE CARE

DIVISION MEMBERS CORE DIVISION MEMBERS Rupert K. S. Chang, MD

Assistant Professor of Pediatrics and Medical Director

Andrew K. Feng, MD

Assistant Professor of Pediatrics

John (Jaime) Harrington, MD

Assistant Professor of Pediatrics and Division Chief

Prashant Purohit, MBBS

Hawaii Health Partners/ Pediatric Critical Care

Len Y. Tanaka, MD, MS

Assistant Professor of Pediatrics

Konstantine P. Xoinis., MD

Assistant Professor of Pediatrics

ADJUNCT MEMBERS James (Jimmy) Kyle, MD

Hawaii Health Partners/ Pediatric Critical Care

Chris Naun, MD

Hawaii Health Partners/ Pediatric Critical Care

Phil Verhoef, MD

Kaiser/Pediatric and Adult Critical Care

DIVISION OVERVIEW

he Pediatric Intensive Care Unit is a 14-bed acute care unit with the capacity to open an additional 4 to 6 beds for intermediate level care patients. Since the opening of the new PICU in the Diamond Head Tower in September, 2016, patients are now all cared for in private rooms, and families have sufficient space to stay with their children during their PICU stay.

We admit approximately 600 children per year with a vast array of medical and surgical problems, ranging from sepsis to congenital heart disease, and respiratory failure. Patients from all over the Pacific are transported to the Kapi‘olani PICU, and we have an active, well-trained, transport team. In addition to caring for patients at Kapi‘olani, our physicians assist in the care of critically ill children at Queen’s Medical Center, and Kaiser Moanalua Medical Center. We are also involved in the care of Medically Fragile children throughout the State.

The PICU team provides complex care to the critically ill patients in our PICU. Continuous renal replacement therapy, plasmapheresis, high-frequency ventilation, and nitric oxide therapy are among the therapies available to our patients. The Hanuola ECMO program has successfully treated many neonatal and pediatric patients since 2007. In 2010, our program was recognized as a Center of Excellence for this type of life support. In September of 2017, ELSO, the national ECMO organization, increased our designation to Gold Level. August 1995, saw the start of “Heart Week.” Since then, 5 times a year for over 20 years, the congenital heart disease program has functioned smoothly with open-heart surgical patients and select interventional cardiac catheterization patients receiving post-procedural care in the PICU. The pediatric trauma collaborative care agreement between the Kapi‘olani PICU and the Surgical/Neuro Intensive Care Unit at Queen’s Medical Center has been very successful. PICU physicians have been providing consultant assistance in the management of pediatric trauma patients hospitalized at Queen’s Medical Center. With the continued development of Kapi’olani’s own trauma service, we have seen more patients being admitted to the PICU for their acute care.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC INTENSIVE CARE Community services include assisting in the medical care of Medically Fragile Children in the community. Members of the PICU staff play an integral role in returning many Medically Fragile Children to their homes, and help provide the medical support necessary to keep them there. We also maintain a close working relationship with the medical staff at Kulana Malama, the Pediatric Nursing Facility in Ewa. We have collaborated in the transitioning of care of Medically Fragile children from the acute setting in the PICU, to the convalescent setting at Kulana Malama.

With his years of experience, Dr. Feng has greatly enhanced the care in our PICU. He is currently overseeing the development of a Pediatric Sedation Scale for the PICU. He has also taken on a leadership role in the Pediatric Residency program, chairing the Program Evaluation Committee. He is active in outreach services, lecturing about various Pediatric Critical Care topics at referring medical centers.

Rupert Chang, MD completed his fellowship at UCSF/ Children’s Hospital Oakland and joined the Critical Care Group at Kapi‘olani Medical Center in 1996. He is Board certified in both Pediatrics and Pediatric Critical Care. Dr. Chang became the Medical Director and Division Chief of the PICU in the fall of 2004. In the fall of 2016, the Division Chief role was assumed by Dr. Jaime Harrington. Dr. Chang continued as PICU Medical Director.

John (Jaime) Harrington, MD joined the PICU in August 2004 after completing his fellowship in Pediatric Critical Care at UCLA in July 2004. He completed his Pediatric residency at Children’s Hospital of Los Angeles and went to Cornell University Medical College. Dr. Harrington was a research fellow in Rio de Janeiro studying tuberculosis, and spent a year as a biomedical researcher in the hematology division of the West Roxbury VA hospital. In the fall of 2016, Dr. Harrington assumed the role of PICU Division Chief, overseeing the PICU group’s role within Hawai‘i Pacific Health and the Department of Pediatrics.

In addition to his clinical duties in the PICU, Dr. Chang works with the PICU Manager, Myra Barrientos, RN, in overseeing the day-today functions of the Intensive Care Unit. Along with the other division members, he is involved in the development of quality improvement measures including the prevention of ventilator associated pneumonia, IV line infections, catheter related UTI’s, and skin breakdown. Dr. Chang has also been very active providing Pediatric Critical care consultant services at Queen’s Medical Center for their pediatric trauma patients and renal transplant patients. He also helped develop the PICU coverage agreement with Kaiser Moanalua Medical Center.

During his free time, Dr. Feng enjoys being with his wife and two children.

Dr. Harrington is an excellent clinician, and has extensive teaching experience. With his outstanding clinical skills, he has greatly enhanced the care of patients in the Intensive Care Unit. Dr. Harrington oversaw the upgrade of the CVVHD program to the Prismaflex pump, and was the physician lead in the development of the Total Plasma Exchange/ Plasmapheresis service at Kapi‘olani Medical Center for Women & Children. Dr. Harrington spends his free time with his husband and family.

During his leisure time, Dr. Chang enjoys spending time with his wife and two daughters.

Andrew Feng, MD joined the PICU in March 2009 after working on the East Coast for a number of years. Dr. Feng received his Pediatric residency training here at Kapi‘olani Medical Center, and served as Chief Resident from 1994 – 1995. He went on to train in Pediatric Critical Care at UCSF/Children’s Hospital Oakland. He completed his training in 1998. As a PICU attending physician, Dr. Feng distinguished himself as an excellent clinician and teacher. He won a number of resident teaching awards at his previous jobs. He is also an accomplished clinical researcher.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC INTENSIVE CARE Prashant Purohit, MBBS FAAP returns to us having completed his Pediatric Critical Care Fellowship at the Lucille Packard Children’s Hospital Stanford. Dr. Purohit received his Medical school training in India, and did his Pediatric Residency training here at Kapi‘olani Medical Center.

into the Pediatric residency at the University of Texas Health Science Center at Houston, where he remained to do his Pediatric Critical Care training.

Since his joining the PICU, Dr. Tanaka is an educator at the medical school and with the pediatric residents. He also took on many Along with the treatment of critically ill children in the PICU, he is additional responsibilities, first serving as the Assistant Director of the passionate about improving health and health care for the children of Pediatric Transport Team for several years, and later becoming the Hawai‘i by research and education. He also has tremendous experience Medical Director of the Hanuola ECMO program of Hawai‘i. In addition in the transport of critically ill children by ground and by air. to leading ECMO program at Kapi‘olani Medical Center, Dr. Tanaka has assisted in the management of ECMO patients at both Straub Medical Center and Queen’s Medical Center. Dr. Purohit is an American Heart Association certified Pediatric Advanced Life Support instructor and he is passionate about teaching cardiopulmonary resuscitation to the providers. He carries monthly In his free time Dr. Tanaka enjoys spending time with his wife and son. mock code and yearly online module in the PICU to strengthen and refresh CPR related skills of PICU nurses and pediatric residents. Konstantine Xoinis, MD joined the PICU division in 2009 after Dr. Purohit is also a part of Pulmonary Hypertension team and as a team member, he oversees the management of patients with pulmonary hypertension, at both out-patient and in-patient level. From research aspect, Dr. Purohit is interested in studying pharmacokinetics of medications used in in the PICU. His overarching goal is to improve safety and efficacy of various medications used in critically ill children.

completing Pediatric Critical Care Fellowship at UCSF/Children’s Hospital Oakland. He did his Pediatric residency training here at Kapi‘olani Medical Center for Women & Children and served as Chief Resident from 2005 – 2006. Dr. Xoinis has varied clinical interests and has made a significant positive impact on patient care in the PICU, sharing his knowledge and insights with the rest of the division. He is the Co-Medical Director of the Pediatric Transport Team, and serves as the Chairperson of the Pharmacy & Therapeutics Committee.

During residency he was awarded with “Raul Rudoy, MD Chairman’s Book Award” and “1st Place Faculty Award Recipient for Research”. He In his free time Dr. Xoinis enjoys spending time with his family. was recently honored by the University of Hawai`i John A. Burns School of Medicine Pediatric Residency Program with the “Resident Teaching Award”, for his excellence in teaching residents. Dr. Purohit oversees the Pediatric Residents and 4th year Medical Students during their PICU rotation. He also has become Resident Research Director for University of Hawai‘i Pediatric Residency Program and member of the Resident Journal Club Directorship. He oversees the scholarly activities of the pediatric residents. In his free time Dr. Purohit enjoys spending time with his wife and daughter. Len Y. Tanaka, MD returned home on September 2007 after completing his Pediatric Critical Care fellowship. He graduated from the University of Hawai‘i John A. Burns School of Medicine before entering

Department of Pediatrics, 2021 Annual Report

Division of Pediatric Specialty Rhiana Lau, MD Division Chief

Kara Yamamoto, MD Associate Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY

DIVISION MEMBERS Pediatric Cardiology

Andras Bratincsak, MD, PhD Dona Brekke, DO D. Venudhar Reddy, MB, BS, MPH Melissa Yamauchi, MD, MPH Pediatric Complex Care Pamela Almeida, PhD, APRN, NNP-BC, CPNP-PC Pediatric Endocrinology Jennifer Concepcion, MD Eludrizza Tabisola-Nuesca, FNP-C, CDE Greg Uramoto, MD Pediatric Gastroenterology Camilla Fraga Lovejoy, MD Jeremy L. King, DO Medical Genetics Leah Dowsett, MD Susheela Jayaraman, MS, MA, CGC Joshua Webster, CGC Pediatric Infectious Disease Rodolfo E. Bégué, MD Natascha Ching, MD Marian Melish, MD Sarah Park, MD Bryscen Makana Prothero, APRN Richard Yanagihara, MD, MPH Pediatric Nephrology Susan Ingraham, MD, PhD Rhiana L.A. Lau, MD* James E. Musgrave, MD Pediatric Neurology Keith Abe, MD Nicole Hodgeboom, CPNP, APRN Sada Okumura, MD Aileen Tanaka, MD Pediatric Physiatry Tamara Zagustin, MD Pediatric Pulmonology Timothy Beaty, MD

Pediatric Rheumatology Pediatric and Adolescent Sports Medicine

Associate Professor of Pediatrics Assistant Clinical Professor of Pediatrics Emeritus Professor of Pediatrics Assistant Clinical Professor of Pediatrics Adjunct Instructor Assistant Clinical Professor of Pediatrics Associate Clinical Professor of Pediatrics Assistant Clinical Professor of Pediatrics Assistant Professor of Pediatrics Assistant Clinical Professor of Pediatrics

Clinical Professor of Pediatrics Assistant Professor of Pediatrics Professor of Pediatrics Assistant Clinical Professor of Pediatrics Professor of Pediatrics Assistant Clinical Professor of Pediatrics Assistant Professor of Pediatrics Professor of Pediatrics Assistant Professor of Pediatrics Associate Clinical Professor of Pediatrics Associate Clinical Professor of Pediatrics Assistant Clinical Professor of Pediatrics

Edward Fong, MD Brian Wu, MD David K. Kurahara, MD Kara S. Yamamoto, MD** Rachel Coel, MD, PhD

Associate Clinical Professor of Pediatrics Assistant Clinical Professor of Pediatrics Professor of Pediatrics Assistant Professor of Pediatrics Assistant Clinical Professor of Pediatrics

Jennifer R. King, DO Christopher Lynch, MD

Assistant Professor of Pediatrics Assistant Clinical Professor of Pediatrics

*Division Chief **Associate Division Chief

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY OVERVIEW

he Pediatric Specialty Division is comprised of individuals with fellowship training in a diverse array of pediatric subspecialties. All of the division members participate in the residency, medical student, and other student teaching programs. Many have been recognized for excellence in teaching with University of Hawai‘i Pediatric Residency and Medical Student teaching awards. Many of our division members are active in quality improvement and clinical research activities, which often include medical students and residents. A few of the specialists are in private practice and the majority are employed by Hawai‘i Pacific Health Medical Group (HPHMG). As a group, we continue to work on strategies to improve care and collaboration for pediatric patients across our specialties as well as within the primary care and hospital settings.

Pediatric Specialty clinics are held at the Kapi’olani office building and the Hale Pawa’a building. Some division members also provide care at other Hawai‘i Pacific Health facilities, Kaiser facilities, and neighbor island outreach clinics. Clinical services in all specialties have expanded to include telemedicine services as well. Our division continues its path of growth; this past year we welcomed Timothy Beaty, MD in Pulmonology; Dona Brekke, DO in Cardiology; Rodolfo Begue, MD in Infectious Diseases; Susheela Jayaraman, CGC and Joshua Webster, CGC in Medical Genetics; Sada Okumura, MD and Aileen Tanaka, MD in Neurology.

From top right: Bryscen Prothero, Rodolfo Begue, Marian Melish, Kara Yamamoto, Keith Abe, Rhiana Lau, Jennifer King, Jennifer Concepcion, Pamela Almeida, Natascha Ching, Christopher Lynch, Leah Dowsett, Edward Fong, Rachel Coel, Drizza Tabisola-Nuesca

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY PEDIATRIC CARDIOLOGY Andras Bratincsak, MD, PhD, is a Pediatric and Adult Congenital Cardiologist, who received his Pediatric Cardiology fellowship training at the University of California San Diego with an additional training in interventional cardiology and electrophysiology of children and adults with congenital heart disease. He is enthusiastic about the education of his peers, residents and medical students. His interest in research originates from his basic science experience at the National Institutes of Health. His translational and clinical research projects have been supported by numerous national and local grants. He has authored over 40 peer reviewed articles and regularly serves as a reviewer to many high profile journals and national institutions. His areas of research include cardiac electrophysiology, ECG analysis using machine learning, and Kawasaki disease.

Pediatric Cardiology is offered as an elective for MS3 students during Pediatric clerkship, MS4 students and Pediatric residents.

PEDIATRIC COMPLEX CARE

Pamela Almeida PhD, APRN, NNP-BC, CPNP-PC, is both a neonatal and pediatric nurse practitioner. She is originally from Massachusetts and received her (BSN) bachelors of nursing degree from the University of Massachusetts – Dartmouth, her (MS – NNP) master of science degree from Northeastern University, her (PNP) post-masters from Maryville University and her PhD from University of Hawai’i in Biomedical Research. She previously worked at Women & Infants’ Hospital and Mass General Hospital in the Neonatal Intensive Care Unit. She joined Kapi‘olani in 2005 in the neonatal intensive care unit and in 2018 started the Pediatric Complex Care Clinic with Dr. Kara Yamamoto. As the Pediatric Complex Care NP she provides both out-patient and inpatient services assisting the medical team and families with the care Dona Brekke, DO, is a Pediatric Cardiologist who joined our practice in coordination of children with complex medical needs. She an invited speaker and has provided guest and keynote lectures at national Nov 2020. advanced practice neonatal nursing conferences. She has developed a Pediatric Complex Care Parent Support group that meets monthly to D. Venudhar Reddy, MD, received his MD from Osmania Medical assist families. She teaches residents, nurses and respiratory therapists College in India and a Master’s in Public Health (MPH) from UCLA. He as an NRP instructor. She is an active participant in ongoing research completed an internship at Fairview Park Hospital in Cleveland and a studies at Kapi’olani Medical Center. She also is a PNP preceptor to Pediatric residency at the University of Missouri Medical Center. After student pediatric and family nurse practitioners. She has participated completing a fellowship in Pediatric Cardiology at UCLA medical Center, as a volunteer in HAPA – Hawai‘i Adaptive Paddling. he became Chief of Maternal Child Health and Crippled Children Services for the State of Alaska and later the State of Hawai‘i. He is the Section Chief for Pediatric Cardiology and Professor of Pediatrics, JABSOM. Dr. Reddy attends the pediatric ward rotation yearly. He is the Medical Director of Pediatric Cardiology at Kapi‘olani Medical Center for Women and Children (KMCWC). His research interests include Kawasaki Disease, rheumatic fever and rheumatic heart disease and congenital heart defects. Dr. Reddy offers a four-week rotation in Pediatric Cardiology to pediatric residents and fourth year medical students. He also offers MS3 clerkship electives to third year medical students.

Melissa Yamauchi, MD, was born and raised in Honolulu, Hawai‘i. She graduated from Oregon Health & Science University, with a combined MD/MPH degree, and completed her pediatric residency at Phoenix Children’s Hospital. She completed her pediatric cardiology training at the University of Utah, which included an additional year focused on non-invasive imaging.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY PEDIATRIC ENDOCRINOLOGY Jennifer Concepcion, MD, attended University of Hawai‘i for her medical school education. She completed her Pediatrics residency at the Children’s Hospital of Orange County, in CA, and her Pediatric Endocrinology fellowship at the University of California San Diego/Rady Children’s Hospital. Her professional interests include precocious puberty, autoimmune thyroid disorders, and growth issues. Drizza Tabisola-Nuesca, FNP-C, CDE, joined the pediatric endocrinology practice in 2015. She received her Family Nurse Practitioner (FNP)/ master’s degree from the Hawai‘i Pacific University, in 2015. She has been passionate with Type 1 Diabetes since working with the Pediatric Gastroenterology & Endocrinology Clinics at Tripler Army Medical Center since 2006. She enjoys keeping up to date with diabetes technology and the current trends with diabetes. She is active in the community and outer islands by helping with education of the school RN’s & NP’s taking care of the children & families living with diabetes, Volunteer at the ADA’s Type 1 Diabetes Camp, and being a guest speaker at conferences. Drizza also facilitates the Clinical Education for DNP students at UH Manoa. Greg Uramoto, MD, is a member of our Clinical Faculty and is an alumnus of JABSOM and our Pediatric Resident Program. His fellowship training was at the Mayo Clinic in Rochester, MN. He has written textbook chapters on Diabetes Mellitus. Pediatric Endocrinology is offered as an elective for Pediatric residents.

PEDIATRIC GASTROENTEROLOGY Camilla Fraga Lovejoy, MD, attended the Federal University of Minas Gerais in Brazil for her medical school education. She completed her Pediatrics residency at the Miami Children’s Hospital and her Pediatric Gastroenterology fellowship at the University of Oklahoma. Her professional interests include nutrition, eosinophilic esophagitis and allergic diseases, intestinal failure and inflammatory bowel disease.

Pediatric Gastroenterology is offered as an elective for Pediatric residents.

MEDICAL GENETICS Leah Dowsett, MD, joined the Medical Genetics practice in Sept 2017. She is an Assistant Clinical Professor of Pediatrics and a clinical geneticist at Hawai‘i Community Genetics. She attended the University of Hawai‘i John A. Burns School of Medicine for medical school and completed her Pediatrics Residency with the Hawai‘i Residency Program. She completed her Medical Genetics and Genomics fellowship at The Children’s Hospital of Philadelphia before returning home. She has presented at national and international meetings. Dr. Dowsett serves on the board for ‘Ahahui o nā Kauka, the Association for Native Hawaiian Physicians. Her professional interests include dysmorphology and improving genomic health disparities in underrepresented minority populations. Susheela Jayaraman, MS, MA, CGC, received her Masters of Science in Genetic Counseling from Northwestern University in 2018. She was certified by the American Board of Genetic Counseling in 2019. She received a Masters of Arts in Medical Humanities and Bioethics from Northwestern University in 2020. Susheela completed a fellowship in the diagnosis and management of lysosomal storage disorders at Ann & Robert H. Lurie Children’s Hospital of Chicago. Susheela joined Hawaii Community Genetics in June of 2020. She currently specializes in pediatric and adult general genetics. She is actively involved in the National Society of Genetic Counselors Public Policy Committee. Susheela is passionate about diversity and equity in graduate education and works closely with Northwestern University and University of Washington graduate programs for genetic counseling. She currently sits on the Ethics Committee at Kapiolani Medical Center for Women and Children. Joshua Webster, CGC, joined the Medical Genetics team in 2020.

Medical Genetics is offered as an elective for preclinical students in MD5, MS3 students during the Pediatric Clerkship, MS4 students, Jeremy L. King, DO, is an Assistant Professor of Pediatrics and Pediatric residents, Ob/Gyn residents, and MFM fellows. We also completed his fellowship in Pediatric Gastroenterology at the Nemours/ provide learning opportunities for genetic counseling students and Alfred I. duPont Hospital for Children in Wilmington, Delaware. He has community learners. busy outpatient and inpatient services at KMCWC and includes the teaching and training of pediatric residents in these activities. Dr. King has written extensively about different issues of Pediatric Gastroenterology and collaborates with the Department of Nutrition at the University of Hawai’i.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY activities, she leads the efforts on the Pediatric antibiotic stewardship program at KMCWC and the Pediatric Department’s Taskforce on The Section of Infectious Diseases is very active both clinically and in Careers in Medicine to encourage high school and college students to research. Led by Dr. Marian E. Melish, who has been in this Department pursue careers in medicine with an emphasis in Pediatrics. She is for more than 40 years, the members support a very active clinical actively working on research involving acute infections, their diagnosis service, which includes both inpatient and outpatient services and also and management with multitude of college students, medical students provide significant support to the community in the form of telephone and pediatric residents. She is on the Infection Control and Prevention consultations. From an organizational perspective, the membership also Committee and the Pharmacy and Therapeutics Committees for the supports the Infection Control and Prevention Department of Kapi‘olani hospital. Dr. Ching has continued to organize the yearly Aloha Pediatric Medical Center for Women and Children including preparedness for Infectious Diseases Conference started by Infectious Diseases colleague New and Emerging Infectious Diseases. The elective in infectious and former Chairman Dr. Rudoy to provide Pediatric Infectious Diseases diseases is a highly sought rotation amongst both medical students and knowledge to our community clinicians. residents, as the clinical cases span not only all of Hawai‘i but also the entire Pacific Basin. The members also coordinate three annual grand Marian E. Melish, MD, is a tenured Professor in the Department. In rounds for the Department of Pediatrics and numerous ID case addition to being a very astute physician supporting the clinical activities conferences throughout the year. of the section, she is also very active in research and her current active research projects include studies in Kawasaki Disease and eosinophilc Rodolfo E Bégué, MD, is a Professor in the Department. Dr Bégué meningitis or neuroangiostrongyliasis caused by the rat lungworm received his medical degree from Universidad Peruana Cayetano (Anglylostrongylus cantonensis). She is also a world renowned expert of Heredia in Lima, Perú (1984). He then completed his Pediatric residency staphylococcal diseases. Dr. Melish is head of Infection Control and at State University of New York/Kings County Hospital in Brooklyn, NY Prevention at the KMCWC. (1986-1989) and Pediatric Infectious Diseases at Brown University/ Rhode Island Hospital in Providence, Rhode Island (1989-1992). After Sarah Park, MD, is a Clinical Assistant Professor in the Department. She Fellowship, he returned to his native Perú to work a clinical trial of a is the Hawaii State Epidemiologist and has been active in this role with cholera vaccine (1992-1994). He then returned to the USA, joining the evaluation and control of the vaccine-preventable infectious Louisiana State University/Children’s Hospital in New Orleans Louisiana diseases in the State. where he functioned for 25 years as faculty member. (1994-2020) He recently joined the Department (2021). Dr Bégué has interest in clinical Bryscen Makana Prothero, APRN, is a board certified Pediatric Nurse service and education. His work and research have centered around Practitioner who joined Hawaii Pacific Health in November of 2018. He vaccines (from lab development to clinical trials), as well as epidemiology, statistics, clinical trial design and global health. He hopes received his Bachelor of Science degree in Biology from the University of Nevada Las Vegas and returned home to Hawai’i to obtain his Masters to continue similar programs in Hawai’i. of Science degree in Nursing at the University of Hawai’i Manoa. He has experience in pediatric primary care, school-based health, physiatry, Natascha Ching, MD, is an Assistant Professor in the Department. Dr. complex care, and currently works with the pediatric infectious disease Ching received her medical degree from the University of Hawai‘i, John department assisting in management of both inpatient and outpatient A. Burns School of Medicine. She completed her pediatric residency at families alongside Dr. Marian Melish and Dr. Natascha Ching. The New York Presbyterian Hospital – Cornell in New York. She pursued subspecialty fellowship training in Pediatric Infectious Diseases at Mattel Richard Yanagihara, MD, is a tenured Professor in the Department. He Children’s Hospital at University of California, Los Angeles. After fellowship, she joined the faculty of UCLA for 7 years where she served is a full time researcher who is based at the School of Medicine and is active with many research infrastructure grants and also international on the clinical ID consultation services and performed research in investigations on new and emerging infectious diseases, particularly Pediatric HIV and Immunocompromised transplant patients. She then those caused by zoonotic viruses. practiced Pediatric Infectious Diseases as an ID consultant in a

PEDIATRIC INFECTIOUS DISEASES

subspecialty group practice and Dell Children’s Medical Center in Austin, Texas for 4 years. She has relocated home in November 2014 to practice Pediatric Infectious Diseases at KMCWC. In addition to her clinical

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY PEDIATRIC NEPHROLOGY

PEDIATRIC NEUROLOGY

Susan Ingraham, MD, PhD, joined the division of Pediatric Nephrology in September 2016. Previously, she was an attending nephrologist and NIH-funded investigator at Nationwide Children’s Hospital in Columbus, Ohio. She provides both inpatient and outpatient consultations in all areas of pediatric nephrology, and enjoys traveling from Oahu to the neighbor islands. Her particular areas of expertise are obstructive nephropathy and congenital anomalies of the kidney and urinary tract. Other interests she hopes to pursue at KMCWC and JABSOM include resident education and collaborative clinical research.

Keith Abe, MD, is an Assistant Professor of Pediatrics and provides inpatient and outpatient neurology consultation services. He completed medical school and Pediatrics residency training at JABSOM and returned to Hawai‘i after completing his child neurology training at Stanford University. He is board certified in pediatrics, neurology with special qualifications in child neurology, and epilepsy. Dr. Abe’s clinical interests include seizures and epilepsy, encephalitis, demyelinating disease, pediatric stroke and neurogenetic disorders. Dr. Abe provides teaching for residents, medical students, and premedical students and serves on the physician advisory board for the Epilepsy Foundation of Hawaii and the Make-A-Wish Foundation.

Rhiana Lau, MD, is an Assistant Professor of Pediatrics and the Division Chief of the Pediatric Specialty Division. She attended medical school at the University of Minnesota. She returned to Hawai‘i after completing her pediatric residency and pediatric nephrology fellowship training at UCLA. She enjoys working with both the residents and medical students rotating at KMCWC and on the pediatric nephrology rotation. In addition to clinical interests in acute kidney injury, obesity-related hypertension, and improving patient compliance, she also has an interest in quality improvement and expansion of telehealth capabilities.

James E. Musgrave, MD, is a Professor of Pediatrics, he is partially retired. Dr. Musgrave’s research interests involve drug trials in pediatric patients with hypertension and epidemiology of pediatric nephrology problems in Hawai‘i. He remains active in the medical school teaching program providing seminars and lectures.

Nicole Hodgeboom, CPNP, APRN, joined the neurology group in 2019. She received her pediatric nurse practitioner (PNP)/master’s degree from the University of California, San Francisco (UCSF) in 2004. Her previous work experience has been with Pediatric Neurosurgery at Stanford Children’s health, where she was the epilepsy surgery lead and involved in the multi-disciplinary Spina Bifida clinic. While working at UCSF, she was a PNP in pediatric pain and palliative care, as well as pediatric liver transplant. Her clinical interests include headache, ADHD and pre and post neurosurgery procedures. She believes laughter is often the best medicine and strives to improve the quality of life for children and families she cares for. Sada Okumura, MD, is an experienced pediatric neurologist who joined our team from Straub Medical Center.

Collectively, the pediatric nephrology service offers consultative services Aileen Tanaka, MD, is a general pediatric neurologist. She completed at KMCWC and other hospitals, nephrology clinic at the Hale Pawa’a medical school at the University of Hawai‘i and pediatrics and pediatric office, and neighbor island outreach clinics. neurology residency at the University of California – San Diego. Her professional interests are the full breadth of pediatric neurology including a special interest in epilepsy. A Pediatric Nephrology rotation is offered to Pediatric residents. A

combined nephrology and rheumatology elective is offered to Pediatric residents and MS4 students. MS3 students have the opportunity to shadow in clinic on their outpatient pediatric rotation.

Pediatric Neurology is offered as an inpatient-outpatient elective to Pediatric residents.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY Edward Fong, MD, is an Associate Clinical Professor of Pediatrics. He received his medical degree from the University of Hawaii-Manoa John Tamara Zagustin, MD, is a Pediatric and Adult physiatrist with A. Burns School of Medicine. He completed his Pediatric internship and additional expertise in Brain Injury Medicine, who received her Pediatric residency as well as his Pediatric Pulmonology Fellowship at the Rehabilitation Medicine fellowship training at the University of Colorado University of Arizona in Tucson, Arizona. During his fellowship, Dr. Fong at the Colorado Children’s Hospital. Her initial Physical Medicine and was awarded a National Institute of Health K30 Clinical Research Rehabilitation training was done at the Universidad Central de Curriculum Award. He also completed the University of Arizona Clinical Venezuela, where she then practiced 7 years before relocating to North Research Training Program. Dr. Fong joined Kapi‘olani Medical America and retraining at the University of Arkansas for Medical Specialists after being in the Bay Area and attending at California Pacific Sciences ( Little Rock). She has had the opportunity to work at Rady’s Medical Center (CPMC) in San Francisco, University of California Benioff Children’s Hospital in San Diego, Queen Elizabeth Hospital in Prince Children’s Hospital at Oakland (UCBCHO), and John Muir Medical Center Edward Island ( Canada), British Columbia Children’s Hospital in (JMMC) in Walnut Creek, California. In addition, Dr. Fong has held Vancouver ( Canada) and at the Children’s Health Care of Atlanta where academic positions as an Assistant Clinical Professor of Pediatrics at she was program director of the Emory University Pediatric both UCSF and Stanford University. Dr. Fong is an avid teacher and Rehabilitation Medicine fellowship. She enjoys partnering with her lecturer, including having mentored 8 pediatric pulmonary fellows prior patients, families, peers, health providers, residents and medical to returning to Hawaii. He has given international and national lectures students to provide the best care to those with complex rehabilitation on the respiratory manifestations of Morquio A Syndrome. He has held needs. leadership positions at CPMC, UCBCHO as well as at Stanford. Currently, he is the Medical Director of Kapi‘olani Medical Center for PEDIATRIC PULMONOLOGY Women and Children’s Respiratory Care Department, including the Pulmonary Function Laboratory. Timothy Beaty, MD is an Assistant Clinical Professor of Pediatrics. He received his medical degree from Saint George’s University. He completed his Pediatric Residency at Tulane University in New Orleans, Brian Wu, MD, is a Pediatric Pulmonologist who received his Pediatric Pulmonary Fellowship training at the University of California San LA and went on to complete his Pediatric Pulmonology Fellowship at Francisco. He is originally from O‘ahu and completed his Pediatric Emory University in Atlanta, GA. During his fellowship, Dr. Beaty was Residency training at the University of Hawai‘i Pediatric Residency awarded a Cystic Fibrosis Foundation Clinical Fellowship Grant. Dr. Program. He holds a certificate in Advanced Training in Clinical Beaty subsequently joined the faculty at Emory University as an Research from UCSF. In addition to providing pediatric pulmonary Assistant Professor. He was awarded grants from the Georgia Clinical and Translational Science Association and Hertz Foundation to complete inpatient and outpatient services, he also provides care for adult a Certificate in Clinical and Translational Research at Emory University. patients with cystic fibrosis. He is an Assistant Clinical Professor at the University of Hawai‘i. Dr. Wu is an advisory member for the Make-AHe was a Co-Director of the CF Scholars program at Emory University and a collaborator of the AsthmaNET national clinical research network Wish Foundation and the Leahi Fund Committee. His passion is clinical of the National Heart Lung and Blood Institute (NHLBI). He subsequently care but also enjoys teaching interested residents and students.

PEDIATRIC PHYSIATRY

rejoined the faculty at Tulane University and was a senior lecturer for the University of Queensland. Dr. Beaty has extensive experience in Pediatrics and Pediatric Pulmonology serving as an attending physician at Scottish Rite Hospital in Atlanta, GA, Egleston Children’s Hospital in Atlanta, GA, and Ochsner Medical Center in New Orleans, LA before joining the faculty at John A Burns School of Medicine at the University of Hawaii.

Pediatric Pulmonology is offered as an elective for Pediatric residents.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY PEDIATRIC RHEUMATOLOGY

PEDIATRIC AND ADOLESCENT SPORTS MEDICINE

David Kurahara, MD, is a Professor of Pediatrics and Program Director for the Pediatric Residency program. Much of his time is overseeing the pediatric residency program but he still has time for research work. His research has shifted from autoantibody work in rheumatic fever to research in graduate medical education. He is currently working on a manuscript in resident research, which was helped by his directorship of the pediatric resident research program for 15 years. He has a team of pre-medical undergraduates helping with these projects, of which he provides direction, mentorship, and experience for them in developing and writing medical manuscripts for publication. He is Vice President and a board member of HPAREF (Hawai‘i Pediatric Association Research and Education Foundation) and also on the medical advisory board for the Make-A-Wish Foundation. As program director of the residency program he sits on almost every committee within the Pediatrics department. He enjoys surfing and is also a volunteer soccer coach for Roosevelt High School.

Rachel A. Coel, MD, PhD, FAAP, CAQSM, is a sports medicine physician board-certified both in general pediatrics and in sports medicine. She specializes in concussion, fracture care, and the prevention and treatment of all sports injuries. She practices at the Kapio’lani Bone and Joint Center, a multi-specialty group of sports medicine physicians, pediatric orthopedic surgeons, and physician assistants that work collaboratively to provide state of the art team based care. Dr. Coel serves as a team physician for Hawaii Pacific University, Chaminade University, Roosevelt High School, Hawai‘i Baptist Academy, and Le Jardin Academy. Dr. Coel is a Clinical Assistant Professor of Pediatrics at the University of Hawai’i, John A. Burns School of Medicine. Dr. Coel grew up in Kailua, Hawaii and graduated from Punahou School. She earned her undergraduate degree at the University of California at Berkeley and her M.D./Ph.D. degrees at the University of Illinois at Urbana-Champaign (Ph.D. in Social Work). Dr. Coel completed her general pediatrics residency at Children’s Hospital Los Angeles and her sports medicine fellowship at the University of Colorado. Dr. Coel’s previous roles included serving as the co-medical director of the sports medicine program at Children’s Hospital Colorado and as Medical Director of the Center for Sports Medicine at Queen’s Medical Center. On her free time, Dr. Coel enjoys surfing, hiking, biking, outdoor sports, eating dessert, and spending time with her husband, daughter, and son.

Kara S. Yamamoto, MD, is an Assistant Professor of Pediatrics and cosection chief of the Pediatric Specialty Division. She works with the Pediatric Residency Program and John A Burns School of Medicine Students. She is the Pediatric Rheumatology Rotation director which is offered as an elective for fourth year Medical Students and Pediatric Residents. Third year medical students on their pediatric clerkship may also rotate through her clinic. She and Dr. David Kurahara provide care for Pediatric Rheumatology patients at the Kapi‘olani Medical Specialists Clinics at Hale Pawa’a and the Kapi‘olani Medical Center for Women and Children. She is also involved with the Pediatric Complex Care Clinic at Kapi‘olani Medical Center for Women and Children. She is a cofacilitator for CATCH (Community Access to Child Health) for the State of Hawai‘i, which is sponsored by the American Academy of Pediatrics. Dr. Yamamoto is a board member of the Arthritis Foundation of Hawai‘i and serves in an advisory role for children with rheumatic diseases. She volunteers with the medical staff of the Special Buddies Camp.

Jennifer R. King, DO, is a board certified pediatric and adolescent sports medicine physician. She specializes in all non-operative sports injuries and has a special interest in dance medicine. Dr. King is also an Assistant Professor of Pediatrics at the University of Hawai’i, John A Burns School of Medicine. She is the rotation director for the Pediatric Sports Medicine Rotation for medical students, residents and fellows. She is faculty member of the Pediatric Department as well as the University of Hawai‘i Sports Medicine Fellowship. She has been involved with numerous youth, high school, collegiate and professional sports teams in her career. She has provided Sports Medicine coverage for events as diverse as the New York City Marathon, AVP Beach Volleyball, Olympic Development Programs and Little League Baseball. Dr. King is a medical advisor for the Hawai‘i Concussion Assessment and Management Program and for the Sports Medicine Advisory Committee of the HHSSA. She is involved in giving community talks about injury prevention both live and virtual as well as a longtime member of the Keiki Injury Prevention Coalition. She practices at the Kapi’olani Bone and Joint Center, a multi-specialty group of sports medicine physicians, pediatric orthopedic surgeons, and physician assistants that work collaboratively to provide state of the art team based care.

Department of Pediatrics, 2021 Annual Report

DIVISION OF PEDIATRIC SPECIALTY Christopher Lynch, MD, is an Assistant Clinical Professor of Pediatrics and completed his pediatric residency at UC Irvine/Children's Hospital of Orange County combined program and his sports medicine fellowship at the University of Hawaiʻi at Mānoa. He volunteers in the community as team physician for local high schools and as sideline physician for UH baseball. Dr. Lynch is a regular speaker at sports medicine conferences on island has a special interest in shoulder injuries and the aquatic athlete. He practices at the Kapio’lani Bone and Joint Center, a multispecialty group of sports medicine physicians, pediatric orthopedic surgeons, and physician assistants that work collaboratively to provide state of the art team based care.

Pediatric Sports Medicine is offered as an elective to Pediatric residents and MS4 students. It is offered as part of the outpatient pediatric rotation for MS3 students. The UH Sports Medicine Fellow and Family Medicine residents rotate through the clinic as part of their training.

Anticipated Division Members starting in the 2020-2021 academic year Mary Hickman, CGC in Medical Genetics

Department of Pediatrics, 2021 Annual Report

Training Program Highlights

Department of Pediatrics, 2021 Annual Report

University of Hawaii Pediatric Resident Program Graduate Career Selections for the Class of 2021

Keisuke Abe, M.D.

Kriselle Gines, M.D

Pediatric Emergency Medicine Fellowship University of New Mexico Albuquerque, NM

General Pediatrics Kokua Kalihi Valley Honolulu, HI

Lindsey Heathcock, M.D.

Amy Jenkins, M.D.

2021-22 UH Pediatric Chief Resident Pediatrician, Hawaii Pacific Health Honolulu, HI

General Pediatrics Wahiawa Health Wahiawa, HI

Rutuja Kibe, M.D.

Rachel Merrifield, M.D.

Neonatology Fellowship University of Southern California Los Angeles, CA

General Pediatrics Palestine Pediatrics Palestine, TX

Rachel Palting, D.O.

Rachel Santiago, M.D.

2021-22 UH Pediatric Chief Resident Pediatrician, Hawaii Pacific Health Applying to Pediatric Endocrinology Fellowship Honolulu, HI

General Pediatrics Straub Medical Center Mililani Town, HI

Department of Pediatrics, 2021 Annual Report

University of Hawai‘i Pediatric Residency Program

2021-2022 Incoming Interns

Anirban Dutta, MB, BS

Mari Grief, MD

Youngtae Kang, MD

Rachel Kwon, DO

North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences

University of Hawai‘i John A. Burns School of Medicine

Chosun University College of Medicine

Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine

Tiffany Lau, MD

Mari Ueno, MD

Joshua Umland, DO

University of Hawai‘i

Thanaporn Ratchataswan, MD

University of Hawai‘i

Western University of Health

John A. Burns School of

Chulalongkorn University

John A. Burns School of

Medicine

Faculty of Medicine

Medicine

Sciences College of Osteopathic Medicine of the Pacific

Department of Pediatrics, 2021 Annual Report

University of Hawai‘i Pediatric Residency Program

2020-2021 Pediatric Residency Program PGY-2

Hanna Distel, MD

Lauren Ishida, MD

Matthew Lim, MD

Jenny Liu, MD

Jaikaran Man Singh, MD

Erika Noel, MD

Jihyun Park, MD

Daniel Truong, DO

Kriselle Gines, MD

Rachel Santiago, MD

PGY-1

Nelly Gutierrez Martinez, MD

Chattip Prueksapraopong, MD

Carrie Ip, MD

Barbora Kadecka, MD

Kornkanok Saringkarisate, MD

Surabhi Khasgiwala, MBBS

Ayush Sidde Gowda, MBBS

Department of Pediatrics, 2021 Annual Report

Resident Honors & Awards July 1, 2020—June 30, 2021 •

Dr. Venu Reddy & Dr. Vijaya Reddy Sponsored Faculty’s Award for Academic Excellence for outstanding educational achievements and strong academic skills

•

Resident Excellence in Clinical Teaching Award

•

Infectious Disease Award

•

Nursing Award for Outstanding Resident (Nightingale Award)

•

Venu & Vijaya Reddy Resident Achievement Award for outstanding educational achievements and model performance of duties as a pediatric house officer for other residents demonstrating commitment to teaching and service

•

Ralph Platou, M.D. Award for exemplifying interest in general pediatrics and serving as a role model for pediatric practice

•

George William Starbuck, M.D. Award for exemplifying an interest in psychosocial problems, demonstrating humanity, showing concerns for social issues, and child health and welfare

•

Hospitalist Award

•

Kenneth M. Ash, M.D. NICU Resident Award for exceptional dedication to NICU patients and their families, colleagues, and the medical profession

•

Calvin C.J. Sia, M.D. Community Pediatrics Advocacy Award for an outstanding pediatric resident who inspires excellence and tireless

Rutuja Kibe, M.D.

•

PICU Award

Rachel Merrifield, M.D.

•

Infectious Disease Award

•

Resident Award for the resident who shows genuine compassion and fellowship toward peers and the recipient is chosen by the residents

•

Chief Award

Rachel Palting, D.O.

•

Drs. Venu and Vijaya Reddy Sponsored Research Award

Kornkanok Saringkarisate, M.D.

•

Infectious Disease Award

•

Venu & Vijaya Reddy Sponsored Chairman’s Book Award for the outstanding PGY-1 resident

Keisuke Abe, M.D.

Lindsey Heathcock, M.D.

Barbora Kadecka, M.D.

Erika Noel, M.D.

Ayush Sidde Gowda, M.B.B.S. 54

Department of Pediatrics, 2021 Annual Report

Resident Research Infrastructure Aloha and greetings from the Resident Research Directors! As Research Directors, we encourage and support the scholarly activity by the residents of University of Hawaii Pediatric Residency Program. Our desire is to train tomorrow’s physicians and healthcare leaders by providing opportunities to practice important skills, like how to develop research ideas, establish goals, practice critical thinking, incorporate feedback, and effectively communicate findings through abstracts at various conferences and by publications. Exploring the ideas of today will help advance pediatric medicine, leading to a healthier future for all children. First of all, many thanks to our pediatric residents! The success of our research curriculum continues to build upon their hard work, passion and dedication. Mahalo nui loa to all the faculty members for mentoring, supporting, and encouraging our residents’ scholarly activity. To support the scholarly activities, we meet with the residents at least every quarter. We review and provide directions in their research work. We help identify and establish their network with the appropriate research mentors. We often help them manage any obstacle that come in their research journey. We also invite internal and external guest lecturers to discuss our resources at Hawaii Pacific Health Research Institution (HPHRI) and University of Hawaii at Manoa and JABSOM. We also conduct educational didactics via lectures on statistics, grant writing, research design and many more. Every year our pediatric residents present their abstracts at various conferences and publish their work in renowned and well respected journals. This is reflective of dedication and commitment of our residents and their mentors. This year on May 20th, 2021, we celebrated our 20th Annual Raul Rudoy Research Day. We had a total of 10 scientific presentations. This special time reflected the ongoing commitment to research and scholarly activity of the Pediatric Residency and Neonatal-Perinatal Medicine Fellowship programs. Awards: First Place: Rachel Palting, DO— “The Health Impact of Pediatric Diabetes and Diabetic Ketoacidosis in Hawaii.” Second Place: Rachel Santiago, MD— “Improving the Rate of Iron Prescribing for Breastfed Infants in a Community Pediatric Clinic in Honolulu.” Third Place: Lindsey Heathcock, MD— “Characteristics of Healthcare Workers with Coronavirus Disease 2019 in Hawaii from March 10, 2020, to May 2, 2020.”

Department of Pediatrics, 2021 Annual Report

Resident Research Infrastructure I would like to take a moment and introduce our Research Director Team members below.

Kenneth Nakamura, MD Professor & Pediatrics Dept. Chair, Kapi‘olani Medical Specialists Chief Medical Officer, Neonatal-Perinatal Medicine

Venkataraman Balaraman, MBBS Dept. Vice Chair & Neonatologist, Kapi‘olani Medical Specialists, Neonatal-Perinatal Medicine Program Director

David Kurahara, MD Professor, Pediatric Rheumatologist Program Director UH Pediatric Residency Program Director

Prashant Purohit, MBBS, FAAP Pediatric Intensivist, Kapi‘olani Medical Specialists Resident Research Director and PICU Rotation Director

Loren Yamamoto, MD, MPH, MBA Professor & Associate Chair of Finance, Dept. of Pediatrics Emergency Medicine, Resident Research Co-Director

Kara Wong-Ramsey, MD Kapi‘olani Medical Specialists, Dept. of Pediatrics Neonatal- Perinatal Medicine Resident Research Co-Director

Akshatha, MD University of Hawai‘i, Dept. of Pediatrics Neonatal-Perinatal Medicine Resident Research Co-Director

Department of Pediatrics, 2021 Annual Report

Resident Research Infrastructure Keynote Speaker: A warm mahalo to our wonderful keynote speaker, Dr. Alika Maunakea. He shared his knowledge, expertise and ongoing research work in “Integrative Epigenomic Analyses Support the Early Developmental Origin of Autism Spectrum Disorders” on that day. We were honored to have him and we will continue to invite such honorable speakers every year on the Annual Research Day.

Once again, I would like to thank everyone who joined us and supported to make this day successful and I appreciate dedication and commitment of our pediatric residents and their mentors.

Alika K. Maunakea, PhD Associate Professor Epigenomics Research Program Department of Anatomy, Biochemistry, and Physiology John A. Burns School of Medicine, University of Hawai'i, Mānoa

Prashant Purohit, MD, FAAP Attending Physician, Pediatric Critical Care Medicine, Department of Pediatrics, Kapiolani Medical Center for Women and Children, Resident Research Director, University of Hawaii, Department of Pediatrics Honolulu, HI

Pictured top left to right: David Kurahara, Prashant Purohit, Loren Yamamoto, Kara Wong Ramsey. Bottom left to right: Lindsey Heathcock, Rachel Palting, Keisuke Abe, Rachel Merrifield, Amy Jenkins, Rutuja Kibe, Kriselle Gines

Department of Pediatrics, 2021 Annual Report

Medical Student Activities

Department of Pediatrics, 2021 Annual Report

at the beginning of the school year. MS1 PIG officers work with the MS2 PIG officers to plan and host PIG activities.

In the school year 2020 to 2021, in the midst of the COVID-19 pandemic, the PIG hosted the following activities:

Aug 2020: By Zoom: Election of new officers, meet Dept of Pediatrics faculty, AED workshop, COVID19 CPR workshop.

Oct 2020: By Zoom: Splint workshop. Students were provided with pre-packages splint kits containing cast padding, stockinette, OrthoGlass, and elastic wraps. Students were instructed in the application of short arm volar, thumb spica, long arm posterior, upper extremity sugar tong, long leg posterior, and lower extremity stirrup splints. Students then broke up into smaller Zoom groups to apply splints to their partners under faculty guidance.

Oct 2020: By Zoom: Chest x-ray and Asthma gadgets workshop. Students were taught how to read a chest X-ray and shown multiple abnormal pediatric chest X-rays. Students taught how to use asthma inhalation devices including, HFA inhalers, spacers, dry powder inhalers, peak flow meters, nebulizers. Students were provided with placebo HFA inhalers. Students then broke up into smaller Zoom groups to demonstrate their inhaler technique under faculty guidance and critique.

Nov 2020: By Zoom: Interesting X-rays workshop. Students were instructed on general principles of reading x-rays. Examples of chest, abdomen, hips, neck, and extremity X-rays were shown.

Pediatrics Interest Group (PIG)

he PIG is among the most active interest groups at UH JABSOM. PIG officers are elected

Jan 2021: By Zoom: Pediatrics Social with Faculty. Students picked up bento dinners at predesignated sites, then joined a Zoom “Social” with faculty. Students participated in games for valuable prizes that included Gimme Gimme scavenger hunt, and “Been There, Done That”.

Feb 2021: By Zoom: Injection workshop. Students were provided with an inject kit that included syringes, needles, a saline vial, alcohol pads, gauze, bandages, and a mini sharps disposal unit. Students were shown how to perform intramuscular (IM), subcutaneous (SQ), and interdermal injections. Between each of these, students broke up into smaller groups to perform these on a partner under faculty guidance/supervision. Students moved between the big group to learn the next injection type and the small groups to perform the injection on their partners.

Apr 2021: By Zoom: Pediatric Specialty Career night. Students picked up Bento dinners at JABSOM, then joined this event by Zoom. UH JABSOM Pediatric faculty in nearly every specialty and subspecialty faculty (in primary care pediatrics, nursery, hospitalist pediatrics, neonatology, pediatric intensive care, pediatric emergency medicine, pediatric cardiology, pediatric pulmonology, pediatric gastroenterology, pediatric nephrology, pediatric endocrinology, pediatric neurology, pediatric hematology/oncology, pediatric rheumatology, adolescent medicine, child abuse, developmental/behavioral pediatrics, sports medicine, genetics) joined the students for this event. Students rotated through pairs of subspecialties every 10 minutes in small groups of 3 to 4 students to ask questions to the faculty. At the end of this, all students and faculty returned to the big group. Faculty then broke up into three groups and students could join any of these group for the final 20 minutes of the event.

Department of Pediatrics, 2021 Annual Report

pediatric residents who discussed their decisions to select pediatrics as their careers, MS4 electives, residency application processes and experiences. In previous (non-COVID) years, the PIG has hosted workshops/events that include: phlebotomy, suturing. Service projects included: Hawaii Pacific Health’s Kids fest. Annual fund raisers include the PIG bake sale. PIG officers have successfully obtained additional funding from the UH Student Activity & Program Fee Board (SAPFB) and from Pediatrics Faculty donations. COVID is down, but not out. We hope that COVID vaccination and control measures will continue to control COVID so that we can get together and have more Pediatrics Interest Group activities in-person with faculty.

Our officers for the 2019-2020 school year: MS3→4: Michaela Tsuha (Pres), Morgan Liu (Pres), Jennifer Lau (Treasurer/Secretary), Lauren Claypoole (media), A.Ken Stridiron (events), Kaimana Kuwada (events) MS2→3: Nicole Nakamatsu (Pres), Kristen Hori (Pres), Kevin Pham (Treasurer/Secretary), Clarke Morihara (Media), Cori Sutton (Events), Kelvin Naito (Events), Jessica Shiosaki (Events), Cali McAllister (Events), Trek Mizoguchi (Events) MS1→2: Anna-Kaelle Ramos (Pres), Nathaniel Villanueva (Pres), Michelle Stafford (Treasurer/Secretary), Emily Leibovitch (Media), Collin Liang (Events), Jaimee Kato (events), Erica Shin (events), Maya Matsumoto (events), Kellie Goya (events), Tori Teramae (events), Ashley Shirriff (events)

Pediatrics Interest Group (PIG)

May 2021: By Zoom: Residency Match with MS4/Resident Panel. Students joined a panel of MS4s and

Incoming MS1s (2020/2021): Carley Kida (VP), Erika Ryckman (VP), Riley Parks(S/T), Michelle Lu (Events), Kerri Niino (Events), Carly Coleman (book drive) Ashley Lee (book drive)

Mahalo,

Loren Yamamoto, MD, MPH, MBA, FAAP, FACEP Professor of Pediatrics, University of Hawai’i John A. Burns School of Medicine Past Chief of Staff & Pediatric Emergency Medicine Attending Physician, Kapi’olani Medical Center for Women & Children

Department of Pediatrics, 2021 Annual Report

Pediatrics Interest Group (PIG) 61

Department of Pediatrics, 2021 Annual Report

Clinical Skills Preceptorship (CSP) Tutors 2020 – 2021 Longitudinal Clinical Mentors Christopher Lynch, David Kurahara, Edward Fong, Jennet Lee Jayaram Jennifer Di Rocco, Jennifer King, Jessica Kosut, Joan Meister, Marian Melish, Pia Francisco-Natanauan, Rachel Coel, Selina Chen, Travis Hong

2020 – 2021 Learning Community Mentors Daniel Murai, Jannet Lee-Jayaram Kyra Len, Mark Pian, Travis Hong

2020 – 2021 Problem Based Learning (PBL) Tutors Balaraman Venkataraman, Barry Mizuo, Cheryl Okado Emmanuel Kling, James Musgrave, Kyra Len Len Tanaka, Loren Yamamoto, Tiffany Wang, Travis Hong

2020 - 2021 Outpatient Preceptors Alicia Turlington, Alyson Tamamoto, Brenda Nishikawa, Brent Matsumoto Brent Tamamoto, Bridgitte Carreau, Brit Reis, Brittney Raffa Carol Titcomb, Caroline Chang, Cindy Colo, Courtney Taum Darret Choy, Derek Flores, Felicitas Livaudais, Gail Nakaichi Gina French, Grace Galiza, Hazel Abinsay, Irene Papaconstadopulos Jenny Welham, Jodie Toward, Jon Ishii, Kara Morita, Kathleen Morimoto-Nishioka, Kristin Hallett, Kristyn Nishimoto Maureen Chang, Melissa Pulling, Michael Hamilton, Michael Treece Michael Walter, Paul Ross, Peter Gregg, Raquel Chan Ikeda Robert Wotring, Robyn Hasegawa, Steven Kaplan, Teresa Bane-Terakubo Terri Tanaka , Trudy Hong, Valerie Besenbruch, Yolanda Wu

Department of Pediatrics, 2021 Annual Report

Departmental Educational Activities

Department of Pediatrics, 2021 Annual Report

Department of Pediatrics—CME Conferences

2020-2021 Thursday Grand Rounds

Department of Pediatrics, 2021 Annual Report

Pediatric Research

Department of Pediatrics, 2021 Annual Report

2020-2021 BY THE NUMBERS

$28.35 M In extramural funding

$25 K

In intramural funding

Journal publications

268 Total faculty members

79 Presentations

Department of Pediatrics, 2021 Annual Report

Departmental Research Report Change in Leadership Venkataraman Balaraman, MBBS was named as the Interim Associate Chair for Research in the Department effective January 2021 with the retirement of Bruce Shiramizu, MD who held this position for several year. During his tenure Dr. Shiramizu working in concert with David Easa, MD was instrumental in getting the first clinical NIH grant in the department which goes by the acronym of HIPACT (Hawai‘i Pediatric and Adolescent Clinical Trials Network).

Grants and Researchers The Departmental faculty have established a very good record in procuring extra-mural grants for various research and service products. For the past several years, the cumulative amounts of these grants have been in excess of $ 1 million annually and the department ranks very highly among the other JABSOM departments in attracting these funds. Active PI’s for grants in the Department include, Venkataraman Balaraman, Andras Bratincsak, Wade Kyono, Charles Neal, May Okihiro and Richard Yanagihara.

IDeA States Pediatric Clinical Trials Network (ISPCTN) Research Currently we are in the second funding cycle for this as a site to recruit patients in IDeA states sponsored pediatric clinical trials. Active projects under collaboration (not all funded under ISPCTN) are: 1. Eat Sleep Console (ESC) approach for management of newborns with Neonatal Opioid Withdrawal Syndrome (NOWS). The site Junior Investigators leading this are Drs. Akshatha and Kara Wong Ramsey under the guidance of Dr. Charles Neal

Children within the US. Drs. Jessica Kosut and Travis Hong will be the faculty PI’s overseeing this study. We also anticipate active recruitment for two additional studies this coming year at our site.

Biomedical Research and Innovation Center (BRIC at HPH) Two of the Departmental faculty members Drs. Andras Bratincsak and Russell Woo along with Dr. Cass Nakasone provide leadership to this center. The center sponsors a one year program in clinical research to interested faculty and is a pathway for faculty development. Funding for the program comes from HPH Medical Group with optimized use of all of HPH wide shared resources supporting research. Three of the Departmental members were BRIC supported faculty this year – Barry Mizuo, Prashant Purohit and Melissa Yamauchi.

HPH Summer Student Research Program (HPH SSRP) This program sponsored by HPH to engage college students in an eight week curriculum in the area of Biomedical Research and exposure to practice of medicine in Hawai‘i. 12-14 students are selected annually. They work with Research mentors primarily on clinical projects. This year several pediatric faculty members were research mentors to the students – Venkataraman Balaraman, Andras Bratincsak, Matthew Careskey, Jennifer King, Douglas Kwock, Len Tanaka, Kara Wong Ramsey, Loren Yamamoto and Melissa Yamauchi.

Children’s Oncology Group (COG) Protocols Dr. Wade Kyono acts as the site PI for all pediatric oncology studies done under the auspices of COG at Kapi‘olani Medical Center for Women and Children

2. Post-Acute Sequelae of COVID-19 (PASC-RECOVER) is a study getting off ground to look at the outcomes in 1000

Department of Pediatrics, 2021 Annual Report

Extramural Research and Training Grants and Contracts Venkataraman Balaraman, MD Current Extramural Grants: FTE Title Role (In Pctg) Ola HAWAII

Other

HIPACT2

Funding Source

Award Date

Project Period

Dollars Awarded

Type of Grant

5.00 NIH

9/21/2017 09/21/2017 -

22,563,872.00 Research

10.00 NIH

9/1/2020 09/01/2020 -

1,000,000.00 Research

Andras Bratincsak, MD, PhD Current Extramural Grants: Title Doxycyline treatment to prevent coronary artery lesions in Kawasaki disease

FTE (In Pctg) Funding Source Award Date

Role PI

0.10 Other: American Heart Association

Project Period

7/1/2018 07/01/2018 06/30/2021

Dollars Awarded

Type of Grant

300,000.00 Research

Maya Maxym, MD, PhD Current Extramural Grants: Title

Role

FTE (In Pctg)

DOH COVID-19 Peds ECHO Series Director

Funding Source

5.00 State

Award Date

Project Period

09/01/2020 10/15/2020 04/30/2021

Dollars Awarded

Type of Grant

15,000.00 Training

Desiree Medeiros, MD Current Extramural Grants: Title Community Counts Public Health Surveillance for Bleeding Disorders

Role

Director

Western States Hemophilia Network Director

FTE (In Pctg)

Funding Source

Other: Center for Disease Control and 20.00 ATHN Other: US Dept of Health and Human Services, Health Resources and 0.00 Services

Award Date

Project Period

Dollars Awarded

Type of Grant

10/01/2019 10/1/2019 09/30/2020

16,000.00 Research

06/01/2019 6/1/2019 05/31/2020

32,330.00 Research

Department of Pediatrics, 2021 Annual Report

Charles Neal, MD, PhD Current Extramural Grants: Title

Role

FTE (In Pctg)

Neonatal Neurobehavior and Outcomes in Very Preterm Infants (Methylation Extension) CO-PI Environmental Influences on Health Outcomes (ECHO) in Former VLBW Infants CO-PI

Funding Source

Award Date

Project Period

Dollars Awarded

Type of Grant

10.00 NIH

10/01/2013 8/1/2013 09/30/2022

11,000.00 Research

10.00 NIH

02/01/2017 9/30/2016 01/31/2023

478,801.00 Research

0.00 NIH

09/21/2017 9/30/2017 08/31/2023

900,000.00 Research

Hawaii IDeA Center for Pediatric and Adolescent Clinical Trials (HIPACT) Other

Jeffrey Okamoto, MD Current Extramural Grants: Title Learn the Signs Act Early Ambassador Grant

Role

FTE (In Pctg)

Funding Source

Award Date

Project Period

Dollars Awarded

Type of Grant

Other: Association of University Centers on 0.00 Disabilities (AUCD)

07/01/2019 3/1/2019 08/21/2022

10,000.00 Training

Enhance Support for Early Childhood Systems Through Act Early Ambassador Program to Support COVID 19 Recovery PI

Other: Association of University Centers on 20.00 Disabilities (AUCD)

09/01/2020 9/1/2020 08/31/2021

94,000.00 Training

May Okihiro, MD Current Extramural Grants: Title

Role

FTE (In Pctg)

Funding Source

Award Date

Project Period

Dollars Awarded

Type of Grant

Hawaii IDeA Center for Pediatric and Adolescent Clinical Trials

Other

5.00 NIH

09/01/2016 9/1/2016 08/30/2020

Wai at Schools

0.00 Local

8/1/2019 08/01/2019 -

92,000.00 Training

Project HANU: Family-centered asthma care and coordination at schools, PI

5.00 Local

04/01/2020 4/1/2020 03/30/2021

50,000.00 Research

1,750,440.00 Research

Department of Pediatrics, 2021 Annual Report

Kara Wong Ramsey, MD Current Intramural Grants (UH' Grants): FTE Title Role (In Pctg) Diabetes Dollars

CO-PI

Award Date

Project Period 05/01/2020 5/1/2020 01/2021

0.00

Dollars Awarded

Type of Grant

2,400.00 Research

Richard Yanagihara, MD Current Extramural Grants: Title

Role

Ola Hawaii

FTE (In Pctg)

Other

Funding Source

Award Date

Project Period

Dollars Awarded

Type of Grant

10.00 NIH

7/1/2019 09/21/2017 -

239,253.00 Research

25.00 NIH

09/08/2020 9/8/2020 04/30/2025

120,000.00 Research

Puipuia le Ola: Increasing reach and uptake of COVID19 testing among Pacific Islanders in Hawaii and Guam PI

0.00 NIH

11/17/2020 11/17/2020 06/30/2022

958,613.00 Research

Pacific Center for Emerging Infectious Diseases Re- PI

25.00 NIH

Research Centers in Minority Institutions (RMCI) Coordinating Center PI

07/01/2015 06/30/2022

750,000.00 Research

Current Intramural Grants (UH' Grants): Title One Health Interdisciplinary Undergraduate Certificate Program PI

Role

FTE (In Pctg)

5.00

Award Date

Project Period

02/01/2020 2/1/2020 10/31/2021

Dollars Awarded Type of Grant

25,000.00 Training

Department of Pediatrics, 2021 Annual Report

Honors & Achievements

Department of Pediatrics, 2021 Annual Report

HONORS & ACHIEVEMENTS Keith Abe, MD – Division of Pediatric Specialty (Neurology) Honolulu Magazine Top Doctors in 2020 & 2021 (continued since 2015) Rupert Chang, MD – Division of Pediatric Intensive Care Listed in Best Doctors National Database Jennifer Di Rocco, DO – Division of Pediatric Hospitalist Medicine Hawaii Magazine Top Doctor 2021 Marissa Fakaosita, MD – Division of Pediatric Hospitalist Medicine

2021 Residency Faculty Teaching Award, University of Hawaii, JABSOM Dept of Pediatrics 2020 Residency Faculty Teaching Award, University of Hawaii, JABSOM Dept of Pediatrics Pia Francisco-Natanauan, MD – Division of Community Pediatrics Honolulu Magazine Top Doctors 2016, 2017, 2018, 2019, 2020 Exemplary Women in Medicine 2019, 2020, 2021 Gina French, MD – Division of Community Pediatrics Honolulu Magazine Top Doctors 2021 Travis Hong, MD – Division of Pediatric Emergency Medicine Leonard Tow Humanism in Medicine Faculty Award Gold Humanism Honor Society Jessica Kosut, MD – Division of Pediatric Hospitalist Medicine Faculty A’o Clinical Teaching Award, Department of Pediatrics, John A. Burns School of Medicine Sheree Kuo, MD – Division of Neonatology Honolulu Magazine Top Doctors 2015 – present Sept 2020 Best Presentation at Pacific Coast Obstetrical and Gynecological Society Annual Meeting. Neonatal hypoxic ischemic encephalopathy and planned home birth. Presented by Dr. Christine Buchanan

Faculty Excellence in Emergency Room Attending Teaching Award, John A. Burns School of Medicine Desiree Medeiros, MD – Division of Pediatric Hematology-Oncology Honolulu Magazine Top Doctor 2021 Marian Melish, MD – Division of Pediatric Specialty (Infectious Disease) Honolulu Magazine Top Doctor 2021 Charles Neal, MD – Division of Neonatology Honolulu Magazine Top Doctor 2015 – 2021 Neonatology Division Chief Brenda (Fujita) Nishikawa, MD – Division of Community Pediatrics Honolulu Magazine Top Doctor 2021 Jeffrey Okamoto, MD – Division of Community Pediatrics Marquiz’s Who’s Who in America 2020 Len Tanaka, MD – Division of Pediatric Intensive Care Pediatric Intensive Care Unit Medical Student Teaching Award Randal Wada, MD – Division of Pediatric Hematology-Oncology Best Doctors in America 2011-2020 Yolanda Wu, MD – Division of Community Pediatrics Honolulu Best Doctors (2015-2021) Kara Yamamoto, MD – Division of Pediatric Specialty (Rheumatology) Honolulu Magazine Top Doctor 2021 Loren Yamamoto, MD – Division of Pediatric Emergency Medicine Honolulu Magazine Best Doctors in Hawaii Award (2011-2014) America’s Best Doctors Award 2016 American Academy of Pediatrics (AAP) Martha Bushore-Fallis Advanced Pediatric Life Support (APLS) Award 2018

Wade Kyono, MD – Division of Pediatric Hematology-Oncology Honolulu Magazine Top Doctor 2021 Rhiana Lau, MD – Division of Pediatric Specialty (Nephrology) Castle Connolly Top Doctor (Hawaii Magazine) Division Chief of Pediatric Specialty Division Jannet Lee-Jayaram, MD – Division of Pediatric Emergency Medicine

Department of Pediatrics, 2021 Annual Report

Departmental Publications & Presentations

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF COMMUNITY PEDIATRICS Publications: 1. Bratincsák, A., Kimata, C., Limm-Chan, B. N., Vincent, K. P., Williams, M. R., & Perry, J. C. (2020). Electrocardiogram Standards for Children and Young Adults Using Z-Scores. Circulation. Arrhythmia and electrophysiology, 13(8), e008253. doi: 10.1161/CIRCEP.119.008253 2. Chin, B., Chan, E. S., & Goldman, R. D. (2014). Early exposure to food and food allergy in children. Canadian family physician Medecin de famille canadien, 60(4), 338–339. 3. Francisco-Natanauan, P., Leatherman-Arkus, N., & Pantell, R. H. (2021). Chlamydia and Gonorrhea Prevalence and Treatment in Detained Youths: Strategies for Improvement. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 68(1), 65–70. doi: 10.1016/j.jadohealth.2020.09.041 4. Ishikawa, T., Chin, B., Meckler, G., Hay, C., & Doan, Q. (2021). Reducing length of stay and return visits for emergency department pediatric mental health presentations. CJEM, 23(1), 103–110. doi: 10.1007/s43678-020-00005-7

5. Limm-Chan, B., Wesseling-Perry, K., Pearl, M. H., Jung, G., Tsai-Chambers, E., Weng, P. L., & Hanudel, M. R. (2021). Associations among erythropoietic, iron-related, and FGF23 parameters in pediatric kidney transplant recipients. Pediatric nephrology (Berlin, Germany), 36(10), 3241–3249. doi: 10.1007/s00467-021-05081-0

Presentations: 1. Francisco-Natanauan, P., Lindsey-Dudley, K., Adair-Leland, J., Peric, A. Presenter. “Adolescent Eating Disorders in Adults: the signs and the science.” Hawaii Academy of Family Physicians Annual (virtual) Conference. February 21, 2021. Honolulu, Hawaii 2. Francisco-Natanauan, P.,M.D., Berger-Chen, S., M.D., Ruggles, M., Esq. Speaker, Panelist. Timely Topics in Pediatrics: Adolescent Privacy. American Academy of Pediatrics-Hawaii Chapter Annual (virtual) Conference. April 22, 2021. Honolulu, Hawaii 3. Turlington, A. "Primary Care During Covid" co-presented with Dr. Josephine Quensell at Pediatric Echo on July 7, 2021 4. Turlington, A. Interdisciplinary Social Justice Seminar "Medical-Legal Partnerships for Homelessness", January 19, 2021, JABSOM Social Justice Interest Group

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF NEONATAL-PERINATAL MEDICINE Publications: 1. Aghagoli1 G, Sheinkopf1 SJ, Everson TM, Marsit C, Lee H, Burt AA, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, O Shea TM, Pastyrnak S, Smith LM, Soliman A, Dansereau LM, Della Grotta SA, Padbury JF, Lester BM (2021) Epigenome-Wide Analysis Identifies Genes and Pathways Linked to Acoustic Cry Variation in Preterm Infants. Pediatric Research. 89:1848-1854. 2. Brampton, C., Pomozi, V., Chen, L. H., Apana, A., McCurdy, S., Zoll, J., Boisvert, W. A., Lambert, G., Henrion, D., Blanchard, S., Kuo, S., Leftheriotis, G., Martin, L., & Le Saux, O. (2021). ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Scientific reports, 11(1), 3881. doi: 10.1038/s41598-021-82966-y 3. Camerota M, Graw S, Everson TM, McGowan EC, Hofheimer JA, O'Shea TM, Carter BS, Helderman JB, Check J, Neal CR, Pastyrnak SL, Smith LM, Dansereau LM, DellaGrotta SA, Marsit CJ, Lester BM (2021) Prenatal risk factors and neonatal DNA methylation in very preterm infants. Clinical Epigenetics. 13:171. doi: 10.1186/s13148-021-01164-9. 4. Chu EK, Smith LM, Derauf C, Neman E, Neal CR, Arria AM, Huestis MA, Della Grotta SA, Roberts MB, Dansereau LM, Lester BM (2021) Behavior Problems During Early Childhood In Children with Prenatal Methamphetamine Exposure. Pediatrics. 146:e20190270. doi: 10.1542/peds.20190270. 5. Everson, T. M., O'Shea, T. M., Burt, A., Hermetz, K., Carter, B. S., Helderman, J., Hofheimer, J. A., McGowan, E. C., Neal, C. R., Pastyrnak, S. L., Smith, L. M., Soliman, A., DellaGrotta, S. A., Dansereau, L. M., Padbury, J. F., Lester, B. M., & Marsit, C. J. (2020). Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infants. Clinical epigenetics, 12(1), 151. doi: 10.1186/s13148-02000942-1 6. Lee JP, Lee WK, Kimata C, Honda A, Neal CR (2021) Impact of a Care Bundle on the Incidence of Necrotizing Enterocolitis in the Neonatal Intensive Care Unit. Neonatology Today. 16:3-13. 7. Oni-Orisan OO, Dansereau LM, Marsit CJ, Smith LM, Neal CR, Della Grotta SA, Padbury JF, Lester BM (2021) DNA methylation in children with prenatal methamphetamine exposure and environmental adversity. Pediatric Research. 10.1038/s41390-020-1058-4. doi: 10.1038/s41390020-1058-4. 8. Shimada, B. K., Pomozi, V., Zoll, J., Kuo, S., Martin, L., & Le Saux, O. (2021). ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions. International journal of molecular sciences, 22(9), 4555. doi: 10.3390/ijms22094555 9. Wood, J. R., Halonen, N. R., Bear, K. A., Campbell, C. E., Wilhelm, P. A., Kling, E., & Rooks, V. J. (2021). Fingertip ultrasound evaluation of umbilical catheter position in the neonatal intensive care unit compared to conventional ultrasound radiography: a preliminary investigation. Journal of perinatology : official journal of the California Perinatal Association, 41(7), 1627–1632. doi: 10.1038/s41372-020-00836-3

Abstracts/Posters: 1. Buchanan C, Kuo S, Minton L, Lee M-J, Choi SY, and Soon R. Neonatal hypoxic ischemic encephalopathy and planned home birth. Oral presentation by C. Buchanan at the Pacific Coast Obstetrical and Gynecological Society Annual Meeting, Virtual Meeting, September 12, 2020. 2. Liu C, Iwamoto L. Late onset hearing loss in very low birth weight premature infants: primarily conductive vs sensorineural. Burrell College of Osteopathic Medicine Student Research Day. July 2020 3. Nishida M, Iwamoto L. NICU family centered rounds under COVID-19 conditions. John A. Burns School of Medicine Biomedical Sciences and Health Disparities Symposium April 2021 4. Merrifield R, Hwang M, Man Singh J, Iwamoto L. Standardization of PDA screening in the NICU at KMCWC: a Quality Improvement Project. UH JABSOM Pediatric Resident Research Day, May 2021

5. Staiger L, Wong Ramsey KN, Kuo S. The effect of maternal blood glucose control on infant body fat composition. Platform presentation at the 44th Annual Conference of the AAP District VIII Section on Neonatal-Perinatal Medicine, Virtual Meeting, June 18, 2021.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 6. Vo K, Iwamoto L. Improve follow up rates for Newborn Hearing Evaluation: a virtual Quality Improvement Project. AAP District VIII Section on Neonatal-Perinatal Medicine Annual Conference, June 2021

Presentations: 1. Iwamoto, L. Standardizing nursing hand-off to Improve Patient Safety, Vermont oxford network annual conference 2020 2. Kawamura M, Wong Ramsey K. Racial Disparities in Breastmilk Receipt and Extremely Low Gestational Age Neonatal Morbidities in an Asian Pacific Islander Population. Hawaii Pacific Health Summer Student Research Presentation 3. Kuo, S. Quality improvement initiatives to decrease necrotizing enterocolitis: a decade long odyssey. Invited speaker at the Academy of Neonatal Nurses Spring 2021 Virtual Advanced Practice & Low Risk Neonatal Nurses Conference. April 16, 2021 4. Wong Ramsey K. Iwamoto I. COVID-19 impact on Neonates in Hawaii. Hawaii Health Partners monthly COVID-19 webinars

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF PEDIATRIC EMERGENCY MEDICINE Publications: 1. Akaishi Y, Okada Y, Lee-Jayaram J, Seo J, Yamada T, Berg BW, Validity Evidence of a task trainer for normal and difficult lumbar puncture: a cross-sectional study. Medicine (Baltimore) 99(41):e22622 doi: 10.1097/MD.0000000000022622. PMID: 33031321; PMCID: PMC7544321 2. Donoghue A, Nagler J, Yamamoto LG. Chapter 3 Airway. In: Shaw KN, Bachur RG (eds). Fleisher & Ludwig's Textbook of Pediatric Emergency Medicine, 8th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2021, print pending. 3. Lee-Jayaram J, Berg BW, Steinemann S, Simulation-Based Training for Post-Graduate Interprofessional Learners. Paige J, et al (eds) Comprehensive Healthcare Simulation: InterProfessional Team Training and Simulation. Springer International, New Jersey, 2020

4. Lee-Jayaram J, Goerner L, Yamamoto LG, MRI Brain for the Pediatric Emergency Department. Pediatric Emergency Care 36(12): 586-590. doi: 10.1097/PEC.0000000000002286. PMID: 33252503. 5. Murata MA, Yamamoto LG. Patient/parent administered epinephrine in acute anaphylaxis. American Journal of Emergency Medicine epub ahead of print November 2020. doi.org/10.1016/j.ajem.2020.10.060 6. Murata MA, Yamamoto LG. Single Versus Double-Sided Hypotheses and Probabilities. Pediatric Emergency Care. 2021;37(7):386-388. doi: 10.1097/PEC.0000000000002477. 7. Nakashima EN, Sutton CXY, Yamamoto LG, Len KA. Wellness Curriculum in the Pediatric Clerkship. Hawai’i Journal of Health & Social Welfare. 2020;79(5,Supp1):50-54. 8. Oikawa S, Berg BW, Lee-Jayaram J, An international, culturally adaptive faculty development fellowship for simulation educators, Medical Teacher 43(8): 914-915, doi: 10.1080/0142159X.2021.1929905

9. Rhodes KL, Nagamine I, Masutani SM, Yamamoto LG. Effects of Environmental and Mechanical Variations on Particle Size Distribution of Albuterol HFA Inhalers. Respiratory Care. 2021 Jul 6;respcare.08858. doi: 10.4187/respcare.08858. Online ahead of print. 10. Sumibcay T J, Lee-Jayaram J, Yamamoto LG (June 13, 2021) Reducing Broad-Spectrum Antibiotic Treatment of Simple Group A Streptococcal Infections to Reduce Harm to the Microbiome. Cureus 13(6): e15629. doi:10.7759/cureus.15629 11. Yamamoto LG. Chapter 230: Abdominal Pain. In: Wolfson AB, Hendey GW, Hendry PL, et al (eds). Harwood-Nuss’ Clinical Practice of Emergency Medicine, 5th edition. Philadelphia: Lippincott Williams & Wilkins, 2020. 12. Yamamoto LG. Chapter 14. Vaccine-preventable illnesses. In: Rose E (ed). Pediatric Emergencies: A Practical Clinical Guide. Oxford University Press, New York, 2020. 13. Yamamoto LG. Chapter 17. The pediatric chest x-ray. In: Rose E (ed). Pediatric Emergencies: A Practical Clinical Guide. Oxford University Press, New York, 2020.

14. Yang I, Yamamoto L. Redesigning the Door Reduces the Potential for Finger Injuries in Children. American Journal of Pediatrics. 2021;7(1):3438. doi: 10.11648/j.ajp.20210701.18

Abstracts/Posters: 1. Abe K, Yamamoto L. Correlation of rail systems with lower traffic fatality rates. Journal of Investigative Medicine 2021;69(1):223. http:// dx.doi.org/10.1136/jim-2021-WRMC 2. Jujo S, Lee-Jayaram J, Nakahira A, Sakka IB, Kataoka A, Izumo M, Kusunose K, Athinartrattanapong N, Berg BW, Development and validation of a cardiac point-of-care ultrasound skill assessment tool for medical students. Presented virtually for the American Society of Echocardiography 31st Annual Scientific Sessions

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 3. Jujo S, Sakka IB, Lee-Jayaram J, Kataoka A, Izumo M, Kusunose K, Nakahira A, Oikawa S, Kataoka Y, Berg BW, Medical student long-term skill retention following cardiac point-of-care ultrasound training based on the American Society of Echocardiography curriculum framework. Presented virtually at the Health Professions Education Conference 4. Lau T, Lim A, Len KA, Yamamoto LG. Can little Annie do chest compressions on Grandpa to save his life in the event of a cardiac arrest? Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID- 19. 5. Lum E, Abey K, Sommer-Candelario S, Delossantos S, Choi S, Lee-Jayaram J, Just-in-Time Training for Video Laryngoscopy in Pediatric Intubations, Presented virtually at the Health Professions Education Conference 6. Lum E, Abey K, Sommer-Candelario S, Delossantos S, Choi S, Lee-Jayaram J, Just-in-Time Training for Video Laryngoscopy in Pediatric Intubations, Presented virtually at the Western Medical Research Conference 7. Miyoshi S, Lee-Jayaram J, Berg BW, An International Simulation Faculty Development Fellowship in Hawaii, Presented virtually at the Association for Medical Education in Europe Conference 8. Mizuo B, Sutton C, Kuniyoshi C, Hong T, Lee-Jayaram J, The Impact of Rater Training on Pediatric Simulation Assessment of Medical Students. Presented virtually at the Health Professions Education Conference 9. Oh S, Hara K, Lee-Jayaram J, Berg BW, Global dissemination of evidence-based simulation education: 10 years experiences from International Journal Club. Presented virtually at the Health Professions Education Conference 10. Rhodes KL, Nagamine I, Masutani SM, Yamamoto LG. Effects of various environmental and mechanical variations on particle size distribution of albuterol HFA inhalers. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID-19. 11. Shiosaki J, Yamamoto L. What are parents reading about the sunscreen controversy? Journal of Investigative Medicine 2021;69(1):132. http:// dx.doi.org/10.1136/jim-2021-WRMC 12. Sumibcay T, Lee-Jayaram J, Yamamoto L. Treating streptococcal pharyngitis with penicillin versus broad spectrum antibiotics. Journal of Investigative Medicine 2020;68(Suppl 1):A2. http://dx.doi.org/10.1136/jim-2019-WMRC

13.Yang I, Yamamoto L. Redesigning the door reduces the potential for finger injuries in children. Journal of Investigative Medicine 2021;69 (1):144. http://dx.doi.org/10.1136/jim-2021-WRMC

Presentations: 1. Abe K, Yamamoto LG. Contribution of Rail systems to Decrease Traffic Fatalities in Children. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID-19. 2. Abe K, Yamamoto LG. Contribution of Rail systems to Decrease Traffic Fatalities in Children. Presented at the Western Student and Resident Medical Research Forum (virtual meeting due to COVID-19) in Carmel, CA, January 2021. Presented by Keisuke Abe, MD 3. Hong, T. “Pediatric Emergencies – Drowning” Module for Pre-Hospital Healthcare Professionals Hawaii Emergency Medical Services for Children 4. Murata MA, Yamamoto LG. Patient/Parent Administered Epinephrine in Acute Anaphylaxis. Presented at the Western Student and Resident Medical Research Forum (virtual meeting due to COVID-19) in Carmel, CA, January 2021. Presented by Michelle Murata. 5. Murata MA, Yamamoto LG. Patient/Parent Administered Epinephrine in Acute Anaphylaxis. Midwest Clinical and Translational Research Meeting CSCTR and MWAFMR (virtual meeting due to COVID-19), April 2021. Presented by Michelle Murata. 6. Murata MA, Yamamoto LG. Single versus Double-Sided Hypotheses and Probabilities. Accepted for presentation at the Pediatric Academic Societies 2021 Virtual Meeting, Vancouver, BC, May 2021. Presented by Michelle Murata.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 7. Lau T, Lim A, Len KA, Yamamoto LG. Can little Annie do chest compressions on Grandpa to save his life in the event of a cardiac arrest? Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID- 19. 8. Lee-Jayaram, J. Invited speaker for The 2021 SAFAR Symposium at the University of Pittsburgh – “Challenges in Maintaining Simulation Excellence” Presented virtually 9. Lim AR, Lau TWS, Len KA, Yamamoto LG. Minimum Weight for Effective Chest Compressions and Alternative Methods for Smaller Rescuer CPR. Poster presentation at the American College of Emergency Physicians Research Forum, Dallas, TX. Meeting converted to virtual meeting due to COVID-19, October 2020. Presented by Anthony Lim. 10. Lim AR, Lau TWS, Len KA, Yammaoto LG. Can Little Anne Do Chest Compressions On Grandpa To Save His Life In The Event Of A Cardiac Arrest? Accepted for poster presentation at the American Heart Association Resuscitation Science Symposium, Dallas, TX, October 2020. We declined this invitation due to AHA’s restriction on multiple meeting acceptances. 11. Liu M, Tsuha M, Hori K, Yamamoto L. Concussions in Female Collegiate Athletes. Presented at the American Academy of Pediatrics National Conference and Exhibition, Section on Sports Medicine, San Diego, CA. Meeting converted to virtual meeting due to COVID-19, October 2020. Presented by Michaela Tsuha and Morgan Liu. 12. Rhodes KL, Nagamine I, Masutani SM, Yamamoto LG. Effects of various environmental and mechanical variations on particle size distribution of albuterol HFA inhalers. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID-19. 13. Settle A, Peric A, Morihara C, Yamamoto L. The Effect of Real-Time Continuous Hemoglobin on the Time to Massive Transfusion Protocol Initiation. Accepted for presentation at the Pediatric Academic Societies 2021 Virtual Meeting, Vancouver, BC, May 2021. 14. Shiosaki J, Yamamoto LG. What are Parents Reading about the Sunscreen Controversy? Presented at the Western Student and Resident Medical Research Forum (virtual meeting due to COVID-19) in Carmel, CA, January 2021. Presented by Jessica Shiosaki. 15. Sumibcay T, Lee-Jayaram JJ, Yamamoto LG. Minimizing Broad Spectrum Antibiotic Treatment of Streptococcal Pharyngitis and Scarlet Fever. Poster presentation at the Western Student and Resident Medical Research Forum (WSMRF). Carmel, CA, January 2020 by Tyrone Sumibcay. 16. Sumibcay T, Lee-Jayaram JJ, Yamamoto LG. Minimizing Broad Spectrum Antibiotic Treatment of Streptococcal Pharyngitis and Scarlet Fever. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID- 19. 17. Sutton CXY, Nakashima EN, Yamamoto LG, Len KA. Wellness Curriculum in the Pediatric Clerkship. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID-19. 18. Tsuha MM, Liu M, Hori KS, Yamamoto LG. Concussions in Female Collegiate Athletes. Accepted for poster presentation at the Pediatric Academic Societies (PAS) meeting in Philadelphia, PA, May 2020; however, meeting was cancelled due to COVID-19.

19. Yang I, Yamamoto LG. Redesigning the Door Reduces the Potential for Finger Injuries in Children. Presented at the Western Student and Resident Medical Research Forum (virtual meeting due to COVID-19) in Carmel, CA, January 2021. Presented by Ivan Yang. 20. Yang I, Yamamoto LG. Redesigning the door reduces the potential for finger injuries in children. Accepted for presentation at the Pediatric Academic Societies 2021 Virtual Meeting, Vancouver, BC, May 2021. Presented by Ivan Yang.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF PEDIATRIC HEMATOLOGY AND ONCOLOGY Publications: 1. Abe K, Dowsett L, Wada R, Hutchins K. A Pediatric Case of Acute Myeloid Leukemia with KMT2A Gene Rearrangement t(10;11) and 16p11.2 Microdeletion Syndrome. Pediatr Blood Cancer, Oct 15, 2020. Epub ahead of print. 2. Bansal N, Amdani SM, Hutchins KK, Lipshultz SE. Cardiovascular disease in survivors of childhood cancer. Curr Opin Pediatr. 2018 Oct;30(5):628 -638. doi: 10.1097/MOP.0000000000000675. 3. Hutchins KK, Callaghan M (2018). Cardiotoxicity among survivors of childhood cancer. Common Cardiac Issues in Pediatrics; Chapter 27. Ed Johnson JN, Kamat DM. 2018. ISBN (electronic): 978-1-61002-145-6.

4. Hutchins KK, Savasan S, Thomas RL, Strathdee LA, Wang ZJ, Taub JW. Clinical Trial Enrollment is Associated with Improved Follow-up Visit Rates among Survivors of Childhood Cancer; J Pediatr Hematol Oncol. 2018. doi: 10.1097/MPH.0000000000001169. 5. Hutchins KK, Steiner R, Lipshultz E, Sallan SE, Lipshultz SE. (2021). Cardiotoxicity after Childhood Cancer Treatment. Late Treatment Effects and Cancer Survivor Care in the Young. Switzerland: Springer. pp. 3-15. 6. Lewis, E. C., Kraveka, J. M., Ferguson, W., Eslin, D., Brown, V. I., Bergendahl, G., Roberts, W., Wada, R. K., Oesterheld, J., Mitchell, D., Foley, J., Zage, P., Rawwas, J., Rich, M., Lorenzi, E., Broglio, K., Berry, D., & Saulnier Sholler, G. L. (2020). A subset analysis of a phase II trial evaluating the use of DFMO as maintenance therapy for high-risk neuroblastoma. International journal of cancer, 147(11), 3152–3159. doi: 10.1002/ ijc.33044 7. Mittal, N., Langevin, A. M., Kyono, W., Dickens, D. S., Grimes, A., Salsman, J. M., Pollock, B. H., & Roth, M. (2021). Barriers to Pediatric Oncologist Enrollment of Adolescents and Young Adults on a Cross-Network National Clinical Trials Network Supportive Care Cancer Clinical Trial. Journal of adolescent and young adult oncology, 10.1089/jayao.2021.0041. Advance online publication. doi: 10.1089/jayao.2021.0041 8. Si SJ, Grupp SA, Dinofia A. Tisagenlecleucel in the treatment of relapsed/refractory pediatric B-cell leukemia. Pediatric Blood Cancer 2021 May; 68(9):e29123. 9. Si SJ, Tasian SK, Bassiri H, Fisher B, Atalla J, Patel R, Romberg N, Lambert M, Paessler M, Behrens E, Teachey DT, Behrens EM, Sullivan KE. Diagnostic Challenges in Pediatric Hemophagocytic Lymphohistiocytosis. J Clin Immunol 2021; 41(6): 1213-1218. 10. Si SJ, Teachey DT. Spotlight on tocilizumab in the treatment of CAR T Cell-induced cytokine release syndrome: clinical evidence to date. Therapeutics and Clinical Risk Management 2020; 19:705-714. 11. Si SJ, Teachey DT. The Hematologist Clinical Trials Corner: Bringing Immunotherapy to the Front-line in Childhood Leukemia. May-June 2020, 17(3): 14-15. 12. Si SJ, Erickson K, Evageliou N, Kersun L, Silverman M. An Usual Presentation of Pneumocystis Jirovecii Pneumonia in a Woman Treated with Immune Checkpoint Inhibitor. Journal of Pediatric Hematology and Oncology 2020 Feb.

13.Wada RK. Leadership, behavioral science, and interprofessional teamwork. Transl Behav Med, 10:905- 908, 2020. Invited peer-reviewed submission for special issue: Translating Skills Learned in the SBMMid Career Leadership Institute into Career Opportunities

Abstracts/Posters: 1. Ramos J, Si SJ, Fujii T, Haun B, Yang WS, Los G, Yu L, Jayanthan A, Dunn S. Targeting B-Raf and Checkpoint Inhibitor Resistant Melanoma with RSK inhibitor PMD-026. Poster presentation, American Association for Cancer Research (AACR), Las Vegas, Nevada, 2021.

2. Si SJ, Barrett DM. Characterization of Immuno-oncologic Landscape in Pediatric Cancers: Uniform TIM-3 and Galectin-9 Positivity on Immunohistochemistry Staining of Tumor Specimen at Diagnosis in Pediatric Patients with Ewing Sarcoma. Poster presentation, American Association for Cancer Research (AACR), San Diego, California, June 2020.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS Presentations: 1. Abe K, Chinen K, Kinoshita H, Dowsett L, Wada R, Kyono W, Glaser D, Jensen J, Medeiros D, Hutchins K. Acute Myeloid Leukemia with MLL Gene Rearrangement t(10;11) and 16p11.2 Microdeletion Syndrome. Poster presented at the 2019 Annual Meeting of the American Society of Pediatric Hematology/Oncology (ASPHO); New Orleans, LA. April 2019. 2. Arkin, J, Hooten K, Thompson KS, Speirs C, Pimenova M, Hutchins K. Primary Intracranial Ewing Sarcoma of the Lateral Ventricle in an Adolescent Female. Poster presented at the 2021 Annual Meeting of the American Society of Pediatric Hematology/Oncology (ASPHO) held virtually. April 2021. 3. Kaneshige R, Hutchins K. The Use of Integrative Medicine in AYA Cancer Survivors. Undergraduate research poster presented at the GW Research Showcase; held virtually. April 2021.

4. Si SJ. CAR T cell therapy in Hawaii: Kapi olani Medical Center Grand Rounds, Honolulu, HI. August 2021. 5. Si SJ. Pediatric Oncology: Pacific Cancer ECHO session, Honolulu, HI. July 2021. 6. Si SJ. CAR T cell therapy in Hawaii: Straub Medical Center Grand Rounds, Honolulu, HI. October 2020.

7. Si SJ. Emerging Therapies and Access Issues in Hawaii: CAR T cell therapy. Oncology Nursing Society Hawaii Annual Conference, Honolulu, HI. October 2020.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF PEDIATRIC HOSPITALIST MEDICINE Publications: 1. Abe, K., Kibe, R., David, K., Reddy, V., Allard, B., & Fakaosita, M. (2021). Reversible right-sided heart failure and pulmonary hypertension caused by scurvy in a 7-year-old boy with autism spectrum disorder and a review of the literature. Paediatrics and international child health, 1 –5. Advance online publication. doi: 10.1080/20469047.2021.1901406 2. Accreditation Council for Graduate Medical Education Pediatrics Milestones Workgroup (Anderson, M; Brantley, C; Buchanan, A; Burke, A; Carraccio, C; Chen, J; Dandekar, A; Dewar, S; Di Rocco, J; Eady, M; Edgar, L; Frohna, J; Gorden, B; Hazinski, MF; Heyman, M; Kas-Osoka, O; Koehn, K; Machogu, E; May, B; Oparaji, JA; Rooney, K; Scheurer, J; Schumacher, D; Shaw, J; Turner, D; Warwick, A; Wolf, K.), Pediatrics Milestones, Second Revision, March 2021, available at https://www.acgme.org/Portals/0/PDFs/Milestones/PediatricsMilestones2.0

3. Annett, R. D., Bickel, S., Carlson, J. C., Cowan, K., Cox, S., Fisher, M. J., Jarvis, J. D., Kong, A. S., Kosut, J. S., Kulbeth, K. R., Laptook, A., McElfish, P. A., McNally, M. M., Pachter, L. M., Pahud, B. A., Pyles, L. A., Shaw, J., Simonsen, K., Snowden, J., Turley, C. B., … Atz, A. M. (2021). Capacity Building for a New Multicenter Network Within the ECHO IDeA States Pediatric Clinical Trials Network. Frontiers in pediatrics, 9, 679516. doi: 10.3389/fped.2021.679516 4. Di Rocco, J, Fakaosita, M, Residency Programs Must Address New Interns’ Divergent Skills, Experience; Commentary in American Academy of Pediatrics News, April 2021, 42(4): 14. 5. Di Rocco JR, Okado, CK, Kimita, C, etal. Patient Safety Initiative Using Peer Observations and Feedback Inspire Collegial Workplace Culture. Hawai’i J Health Soc Welf. 2020 May 1; 79(5 Suppl 1): 112-117. 6. Johnson SC, Kosut JS, Ching N. Disseminated Cat Scratch Disease in Pediatric Patients in Hawaii. Hawaii Journal of Health and Social Welfare. 2020;79(5 suppl 1):47-53.

7. Kosut J. Keeping Children Out of School Causes Unnecessary Harm. Honolulu Star Advertiser. October 12 2020. 8. Kurahara, D., Hamamura, F. D., Ifuku, C., Chen, J. J., Liu, C. A., Seamon, E. M., Miwa, C. S., Maestas, B., Oba, R., Patel, S. J., & Shiramizu, B. (2020). Medical School Location and Sex Affect the In-State Retention of Pediatric Residency Program Graduates in Hawai'i. Hawai'i journal of health & social welfare, 79(8), 240–245. 9. Okado, CK, Teramae, T. Antibiotic Practice Change to Curtail Linezolid Use in Pediatric Hospitalized Patients in Hawai’i with Uncomplicated Skin and Soft Tissue Infections. Hawai’i J Health Soc Welf. 2020 May 1; 79(5 Suppl 1): 87-90. 10. Rosenbluth, G., Good, B. P., Litterer, K. P., Markle, P., Baird, J. D., Khan, A., Landrigan, C. P., Spector, N. D., Patel, S. J., & SHM I-PASS SCORE Study Group (2020). Communicating Effectively With Hospitalized Patients and Families During the COVID-19 Pandemic. Journal of hospital medicine, 15(7), 440–442. doi: 10.12788/jhm.3466 11. Shiramizu B, Okihiro MM, Kosut JS, Wu BH, Akshatha A, Neal C, Amiotte A, Siu A, Lee MJ, Balaraman V, Easa D. Hawai’i IDeA Center for Pediatric and Adolescent Clinical Trials. Hawaii Journal of Health and Social Welfare. 2020;79(5 suppl 1):3-6. 12. Taenzer, A. H., Patel, S. J., Allen, T. L., Doerfler, M. E., Park, T. R., Savitz, L. A., Park, J. G., & Members of the High Value Healthcare Collaborative (2020). Improvement in Mortality With Early Fluid Bolus in Sepsis Patients With a History of Congestive Heart Failure. Mayo Clinic proceedings. Innovations, quality & outcomes, 4(5), 537–541. doi: 10.1016/j.mayocpiqo.2020.05.008

Presentations: 1. Di Rocco, J. Milestones 2.0 “Table to Able” Sessions 1 and 2. Association of Pediatric Program Directors’ National Meeting, Zoom Conference, March 23-26, 2021. (Invited Facilitator) 2. Di Rocco, J., Olson, H. Deliberate Dialogues: Clinical Competency Committee Best Practices. Hawaii Regional Graduate Medical Education Leadership Meeting and Faculty Development Conference, Honolulu, HI, April 20, 2021. (Invited Panelist)

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 3. Di Rocco, J. Supporting Childhood Development and Resilience During Pandemic-Disrupted Education.Hawaii Pediatric Extension for Community Healthcare Outcomes, Zoom Conference, February 17, 2021. (Invited Speaker) 4. Gavero, G., Len, K., Di Rocco, J. Time Out to Tune In, Ola HAWAII Mentoring Bootcamp, John A. Burns School of Medicine, Honolulu, HI, June 1, 2021. (Invited Speaker) 5. Gavero, G., Len, K.A., Di Rocco, J. (2021 June 1). Time Out to Tune In: Reflections on Personal Time Management, Productivity and Balance. Ola Hawai’i Mentoring Bootcamp. John A. Burns School of Medicine, Honolulu, HI. (Invited Speaker). 6. Gavero, G., Len, K., Di Rocco, J. Work-Life Balance & Time Management. JABSOM Graduate Medical Education Kukakuka (Talk Story) Series, June 21, 2021. (Invited Panelist) 7. Kornkanok Saringkarisate, Ching, N., Len, K.A., Prothero, B., Melish, M. (2021 April 15). Neonatal Varicella Meningitis Caused By Vaccine-Strain After Postpartum Maternal Varicella Vaccination Rash. Biomedical Symposium, Honolulu, HI. (Oral Presentation). 8. Kosut J. A Crick in the Neck: When it is more than just muscle stiffness. Pediatric Hospital Medicine Conference, Conundrum E-Poster, July 2020. 9. Kosut J. SCORE and Families, Community Advisory Council, Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, January 27, 2021. 10. Kosut, J. 2021: Invited Presentation: SCORE Collaborative National Quarterly Meeting. “Utilization of Telehealth on Family Centered Rounds During the COVID-19 Pandemic.” September 28, 2021. 11. Kurashima C, Fakaosita M, Kosut J. Pediatric Bronchiolitis Admissions: What opportunities exist to safely and cost-effectively improve patient care? Biomedical Sciences and Health Disparities Symposium, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, April 16, 2021.

12. Kurashima C, Fakaosita M, Kosut J. Pediatric Bronchiolitis Admissions: What opportunities exist to safely and cost-effectively improve patient care? Hawaii Pacific Health, Summer Student Research Program, Honolulu, Hawaii, August 13, 2020. 13. Lau, T.W.S., Lim, A.R., Len, K.A., Yamamoto, L.G. (2021, April 30—May 4). Weight requirement for CPR chest compressions; can children deliver sufficient chest compressions to save the life of a grandparent? Pediatric Academic Societies Meeting. Virtual Meeting, May 2021. (Poster Presentation) 14. Len, K.A., Di Rocco, J., Gavero, G. (2021 June 21). Work-life Balance and Time Management. GME Kukakuka (Talk Story) Series. John A. Burns School of Medicine, Honolulu, HI. (Invited Speaker). 15. Len, K.A., Lee-Jayaram, J., Peric, A., Asato, C., Siu-Li, N., Wong, V.S. (2021 Feburary 13). Connection + Collaboration + Compassion = Learning Communities. Health Professions Education Conference (HPEC) Virtual Conference, Honolulu, HI. (Panel Presentation) 16. Liebovitch E, Kosut J, DiRocco J, Lin, J, Patel S. The unexpected benefits of telemedicine use for family centered rounds during the COVID-19 pandemic. Oral Abstract, Biomedical Sciences and Health Disparities Symposium, John A. Burns School of Medicine, University of Hawai‘i, Honolulu, Hawai‘i, April 15, 2021. 17. Lim A.R., Lau T..WS., Len K.A., Yamamoto L.G. Can Little Anne Do Chest Compressions On Grandpa To Save His Life In The Event Of A Cardiac Arrest?. Accepted for poster presentation at the American Heart Association Resuscitation Science Symposium, Dallas, TX, October 2020. We declined this invitation due to AHA’s restriction on multiple meeting acceptances. 18. Lim A.R., Lau T.W.S., Len K.A., Yamamoto L.G. Minimum Weight for Effective Chest Compressions and Alternative Methods for Smaller Rescuer. Accepted for poster presentation at the American College of Emergency Physicians Research Forum, Virtual Meeting, October 2020. 19. Lim M.A., Patel S.J. Striving for perfection through continuous improvement: HPH’s Pier 2 COVID-19 mass vaccination site. Oral Abstract, Biomedical Sciences and Health Disparities Symposium. University of Hawai‘i John A. Burns School of Medicine, Honolulu, HI, April 15, 2021.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 20. Mizuo B and Kosut J. Multisystem Inflammatory Syndrome in Children and Adolescents: Comparing the US and Italian Experiences, Pediatric Hospital Medicine Journal Club, Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, August 20, 2020. 21. Tamamoto, K., Rousslang, N., Nakashima, E., Morihara, C., Peric, A., Murayama, S., Len, K.A., Wong, V. (2021 February 13). Curriculum Development for JABSOM s Learning Communities: Medical Ethics. Health Professions Education Conference (HPEC) Virtual Conference, Honolulu, HI. (Poster Presentation) 22. Taum, C.K., Ishida, L., Hong, T., Mizuo, B. Len, K.A. (2021, April 6-9). Preparing for the Pediatric Clerkship: MSPREP Medial Student Preparatory Resource to Excel in Pediatrics. Council on Medical Student Education in Pediatrics (COMSEP) Meeting. Virtual Meeting, April 2021. (Poster Presentation)

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF PEDIATRIC INTENSIVE CARE Publications: 1. Bratincsak A, Liu J, Yalamanchili R, Purohit PJ, Xoinis KP, Yamauchi MSW. Junctional Tachycardia as a Diagnostic Criterion in Acute Rheumatic Fever. Pediatrics. 2021 Jun;147(6):e2020049361. doi: 10.1542/peds.2020-049361. Epub 2021 May 5. 2. Garrett Kuwada, BS ; Aiko Murakami, BS ; Darryl W Glaser, MD ; Susan E Ingraham, MD, PhD ; Prashant J Purohit, MD FAAP. Mothball ingestion in the setting of G6PD deficiency causing severe hemolytic anemia, methemoglobinemia, and multiple organ failure in a toddler. Accepted for publication for Hawai‘i Journal of Health and Social Welfare. 3. Johnson, Scarlett; Feng, Andrew; Tanaka, Len; Purohit, Prashant. 865: Safety and Efficacy of Dexmedetomidine in a Single-Center Pediatric Intensive Care Unit, Critical Care Medicine: January 2021 - Volume 49 - Issue 1 - p 429. doi: 10.1097/01.ccm.0000729348.38414.26 4. Johnson, S. C., Fong, E., Wu, B., Kyono, W., Chang, R., Reddy, V., & Purohit, P. J. (2020). Respiratory Distress in a 5 Week Old. Clinical pediatrics, 59(6), 625–628. doi: 10.1177/0009922820913959 5. Knight L, Pahud BA, Scheffler M, Euteneuer JC, Allen C, Ross J, Ali W, Meyer M, Purohit PJ, Zimmerman KO, Sullivan JE; Environmental Influences on Child Health Outcomes (ECHO) Institutional Development Award (IDeA) States Pediatric Clinical Trials Network. Capacity Building in a New Clinical Trials Network through Inter-Network Collaboration. J Pediatr. 2021 Apr 30:S0022-3476(21)00414-5. doi: 10.1016/ j.jpeds.2021.04.062. Epub ahead of print. PMID: 33940019. 6. Levy, Danielle; Fong, Edward; Wu, Brian; Careskey, Matthew; Xoinis, Konstantine; Harrington, John; Tanaka, Len; Purohit, Prashant. 992: Sevoflurane to the Rescue: A Convoluted Case of Respiratory Failure in an Asthmatic Teenager, Critical Care Medicine: January 2021 - Volume 49 - Issue 1 - p 494. doi: 10.1097/01.ccm.0000729856.48260.2f 7. Nogues, Marina; Tanaka, Len; Chang, Rupert; Harrington, John; Ching, Natascha; Melish, Marian; Abe, Keith; Purohit, Prashant. 783: Therapeutic Plasma Exchange for the Treatment of Super-Refractory Status Epilepticus and FIRES, Critical Care Medicine: January 2021 Volume 49 - Issue 1 - p 388 doi: 10.1097/01.ccm.0000729020.46669.b9

8. Purohit PJ, Yamamoto L, Tanaka LY, Xoinis K, Harrington J, Chang R, Feng A. Pediatric Code Blue: How Prepared Are We? A Self-Efficacy Assessment Project. Hawaii J Health Soc Welf. 2020; 79:122-6. PMID: 32490399.

Abstracts/Posters: 1. S Johnson, AK Feng, L Tanaka, P Purohit. Safety and efficacy of dexmedetomidine in a single-center pediatric intensive care unit. Critical Care Medicine. January 2021. 49(1):429.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS

DIVISION OF SUBSPECIALTY Publications: 1. Abe K, Dowsett L, Wada R, Hutchins K. A pediatric case of acute myeloid leukemia with KMT2A Gene Rearrangement t(10;11) and 16p11.2 microdeletion syndrome. Pediatric Blood & Cancer, October 15, 2020. Letter to the editor. PMID:33058483. 2. Abolfazli M, Host-Madsen A, Zhang J, Bratincsak A. Graph coding for model selection and anomaly detection in Gaussian graphical models. IEEE. In press 2021. 3. Ansdell, V., Kramer, K. J., McMillan, J. K., Gosnell, W. L., Murphy, G. S., Meyer, B. C., Blalock, E. U., Yates, J., Lteif, L., Smith, O. A., & Melish, M. (2021). Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations. Parasitology, 148(2), 227–233. doi: 10.1017/S0031182020001262 4. Bennie, A., Suessman, A., Beaty, T., & Warrier, R. (2020). Hemoptysis in a Healthy Teenager. Clinical pediatrics, 59(9-10), 943–946. doi: 10.1177/0009922820922533 5. Bratincsák A, Kimata C, Limm-Chan BN, Vincent KP, Williams MR, Perry JC. Electrocardiogram standards for Children and adults using Z-scores. Circ Arrhythm Electrophysiol. 2020; 13:e008253. 6. Bratincsak A, Hong TM, Melish ME. Acute adult-onset Kawasaki disease complicated by coronary artery aneurysms, thrombosis, and STsegment elevation myocardial infarction. J Am Coll Cardiol Case Rep. 2021:3:276-279. 7. Bratincsak A, Yalamanchili R, Liu J, Purohit P, Xoinis K, Yamauchi M. Junctional tachycardia as a new diagnostic criterion for acute rheumatic fever. Pediatrics. In press 2021. 8. Cook, J.A., Arai, S., Armién, B., Bates, J., Carrion Bonilla, C.A., de Souza Cortez, M.B., Dunnum, J.L., Ferguson, A.W., Johnson, K.M., Khan, F.A.A., Paul, D.L., Reeder, D.M., Revelez, M.A., Simmons, N.B., Thiers, B.M., Thompson, C.W., Upham, N.S., Vanhove, M.P.M., Webala, P.W., Weksler, M., Yanagihara, R., and Soltis, P.S.: Integrating biodiversity infrastructure into pathogen discovery and mitigation of emerging infectious diseases. BioScience 70, 531-534, 2020. PMCID: PMC7340541. 9. Dowsett L and Enos S. Depiction of Hāloa by Solomon Enos. ACMG Part C. May 13, 2021. Vol 187 (2): p. 265-268. PMID: 33982419. 10. Fittipaldi, N., Collis, T., Prothero, B., & Gottschalk, M. (2009). Streptococcus suis meningitis, Hawaii. Emerging infectious diseases, 15(12), 2067 –2069. doi: 10.3201/eid1512.090825 11. Fukuda A, Katz, AR, Park, IU, Komeya, AU, Chang, A, Ching, Natascha, Tomas, JE, and Wasserman, GM. Fukuda A, Katz AR, Park IU, Komeya AY, Chang A, Ching N, Tomas JE, Wasserman GM. Congenital Syphilis: A Case Report Demonstrating Missed Opportunities for Screening and Inadequate Treatment Despite Multiple Health Care Encounters During Pregnancy. Sex Transm Dis. 2021 Sep 1;48 (9):e124 e125. doi: 10.1097/ OLQ.0000000000001352. PMID: 34110747. 12. Grand K, Skraban S, Cohen J, Dowsett L, Mazzola S, Tarpinian J, Bedoukian E, Nesbitt A, Denenberg B, Lulis L, Santani A, Zackai E, and Deardorff M. Nonlethal Presentations of CYP26B1-related skeletal anomalies and multiple synostoses syndrome. ACMG Part A, June 23 2021. PMID: 34160123. 13. Guillet R, Selewski DT, Griffin R, Rastogi S, Askenazi DJ, D'Angio CT; Neonatal Kidney Collaborative incl. Ingraham S. Relationship of patent ductus arteriosus management with neonatal AKI. J Perinatol. 2021 Jun;41(6):1441-1447. doi: 10.1038/s41372-021-01054-1. Epub 2021 Apr 19. PMID: 33875795 14. Hedges, J.R., Soliman, K.F.A., Southerland, W.M., D Amour, G., Fernández-Repollet, E., Khan, S.A., Kumar, D., Shikuma, C.M., Rivers, B.M., Yates, C.C., Yanagihara, R., Thompson, W.E., Bond, V.C., Harris- Hooker, S., McClure, S.A., and Ofili, E.O.: Strengthening and sustaining interinstitutional collaborations and partnerships. International Journal of Environmental Research and Public Health 18, 2727, 2021. PMCID: PMC7967451. https://doi.org/10.3390/ijerph18052727

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 15. Hu, L., Chen, S., Fu, Y., Gao, Z., Long, H., Wang, J., Ren, H., Zuo, Y., Li, H., Xu, Q., Yu, W., Liu, J., Shao, C., Hao, J., Wang, C., Ma, Y., Wang, Z., Yanagihara, R., and Deng, Y.: Risk factors associated with clinical outcomes in 323 COVID-19 hospitalized patients in Wuhan, China. Clinical Infectious Diseases 71, 2089-2098, 2020. PMCID: PMC7197620. 16. Jang, W.S., Lim, D.H., Yoon, J., Kim, A., Lim, M., Nam, J., Yanagihara, R., Ryu, S.W., Jung, B.K., Ryoo, N.-H., and Lim, C.S.: Development of a multiplex loop-mediated isothermal amplification (LAMP) assay for on site diagnosis of SARS-CoV-2. PLoS One 16 (3), e0248042, 2021. PMCID: PMC7928493. doi: 10.1371/journal.pone.0248042. 17. Jayaraman S, Koenig S, Fiddler M, Simi E, Goldenberg A, Magasi S, Wicklund C. Prenatal genetic counselors' perceptions of the impact of abortion legislation on counseling and access in the United States. J Genet Couns. 2021 Jun 6. doi: 10.1002/jgc4.1433. Epub ahead of print. PMID: 34096144. 18. Kikuchi, F., Aoki, K., Ohdachi, S.D., Tsuchiya, K., Motokawa, M., Jogahara, T., Nguy?n, S.T., Bawm, S., Lin, K.S., Thwe, T.L., Gamage, C.D., Ranorosoa, M.C., Omar, H., Maryanto, I., Suzuki, H., Tanaka-Taya, K., Morikawa, S., Mizutani, T., Suzuki, M., Yanagihara, R., and Arai, S.: Genetic diversity and phylogeography of Thottapalayam thottimvirus (Hantaviridae) in Asian house shrew (Suncus murinus) in Eurasia. Frontiers in Cellular and Infection Microbiology 10, 438, 2020. PMCID: PMC7481397. 19. Kurahara DK, Hamamura FD, Ifuku C, Chen JJ, Maestas B, Liu CA, Seamon E, Patel SJ, Shiramizu B. Gender and Medical School Location Affect the In-State Retention of Pediatric Residency Program Graduates in Hawaii. Hawai‘i Journal of Med & Pub Health. Hawaii J Health Soc Welf. 2020 Aug 1; 79(8): 240–245. PMCID: PMC7417638 20. Lee, S.-H., No, J.S., Kim, W.-K., Gajda, E., Perec-Matysiak, A., Kim, J.-A., Hildebrand, J., Yanagihara, R., and Song, J.-W.: Molecular epidemiology and genetic diversity of orthohantaviruses in small mammals in western Poland. American Journal of Tropical Medicine and Hygiene 103, 193199, 2020. PMCID: PMC7356445. 21. Limm-Chan B, Musgrave J, Lau R, Ahn HJ, Nguyen L, Kurahara D. Incidence of Acute Post- Streptococcal Glomerulonephritis in Hawai'i and Factors Affecting Length of Hospitalization. Hawaii J Health Soc Welf. 2020;79(5):149-152. 22. Liphardt, S.W., Kang, H.J., Arai, S., Gu, S.H., Cook, J.A., and Yanagihara, R.: Reassortment between divergent strains of Camp Ripley virus (Hantaviridae) in the northern short-tailed shrew (Blarina brevicauda). Frontiers in Cellular and Infection Microbiology 10, 460, 2020. PMCID: PMC7509084. 23. Man Singh J, Palting RL, Bratincsak A. Junctional tachycardia due to Multisystem Inflammatory Syndrome in Children with SARS-CoV-2 infection in a 12-year-old female. Cardiol Young. 2021;7:1-7. 24. Muff-Luett M, Sanderson KR, Engen RM, Zahr RS, Wenderfer SE, Tran CL, Sharma S, Cai Y, Ingraham S, Winnicki E, Weaver DJ, Hunley TE, Kiessling SG, Seamon M, Woroniecki R, Miyashita Y, Xiao N, Omoloja AA, Kizilbash SJ, Mansuri A, Kallash M, Yu Y, Sherman AK, Srivastava T, Nester CM. Eculizumab exposure in children and young adults: indications, practice patterns, and outcomes-a Pediatric Nephrology Research Consortium study. Pediatr Nephrol. 2021 Aug;36(8):2349-2360. doi: 10.1007/s00467-021-04965-5. Epub 2021 Mar 10. PMID: 33693990 25. Park, J., Brekke, D. R., & Bratincsak, A. (2021). Self-limited myocarditis presenting with chest pain and ST segment elevation in adolescents after vaccination with the BNT162b2 mRNA vaccine. Cardiology in the young, 1–4. Advance online publication. doi: 10.1017/ S1047951121002547 26. Powell, L. N., & Bégué, R. E. (2020). Influenza Vaccine Effectiveness Among Children for the 2017-2018 Season. Journal of the Pediatric Infectious Diseases Society, 9(4), 468–473. doi: 10.1093/jpids/piz077 27. Ofili, E.O., Sarpong, D., Yanagihara, R., Tchounwou, P.B., Fernández-Repollet, E., Malouhi, M., Lawson, K., Spring, N.H., Idris, M.Y., and Rivers, B.: The Research Centers in Minority Institutions (RCMI) consortium: A blueprint for inclusive excellence. International Journal of Environmental Research and Public Health 18, 6848, 2021. PMCID: PMC8296926. https://doi.org/10.3390/ijerph18136848 28. Selewski DT, Gist KM, Nathan AT, Goldstein SL, Boohaker LJ, Akcan-Arikan A, Bonachea EM, Hanna M, Joseph C, Mahan JD, Mammen C, Nada A, Reidy K, Staples A, Wintermark P, Griffin R, Askenazi DJ, Guillet R; Neonatal Kidney Collaborative incl Ingraham S. The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group. Pediatr Res. 2020 Feb;87(3):550-557. doi: 10.1038/s41390-0190579-1. PMID: 31537009.

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 29. Slowik, V., Hildreth, A., Pacheco, M. C., Finn, L. S., King, J., Shivaram, G., Files, M., Hsu, E. K., & Horslen, S. (2020). Hepatopulmonary Syndrome in an Adolescent With Insidious Hypoxia and Small Intrahepatic Portal Venous Shunts: Posttransplant Benefit From Sildenafil. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 23(6), 467–471. doi: 10.1177/1093526620945951 30. Starr MC, Boohaker L, Eldredge LC, Menon S, Griffin R, Mayock D, Askenazi D, Hingorani S; Neonatal Kidney Collaborative incl Ingraham S. Acute Kidney Injury is Associated with Poor Lung Outcomes in Infants Born ≥32 Weeks of Gestational Age. Am J Perinatol. 2020 Jan;37(2):231240. doi: 10.1055/s-0039-1698836. PMID: 31739364 31. Starr MC, Boohaker L, Eldredge LC, Menon S, Griffin R, Mayock DE, Li L, Askenazi D, Hingorani S; Neonatal Kidney Collaborative incl Ingraham S. Acute Kidney Injury and Bronchopulmonary Dysplasia in Premature Neonates Born Less than 32 Weeks' Gestation. Am J Perinatol. 2020 Feb;37(3):341-348. doi: 10.1055/s-0039-3400311. PMID: 31777046

32. Tekendo-Ngongang C, et al, …Dowsett L, …Muenke M. Rubenstein-Taybi Syndrome in Diverse Populations. AJMG Part A, September 5, 2020. Vol 182A:2939-2950. PMID: 29681090. 33. Yanagihara, R., Berry, M.J., Carson, M.J., Chang, S.P., Corliss, H., Cox, M.B., Haddad, G., Hohmann, C., Kelley, S.T., Lee, E.S., Link, B.G., Noel, R.J., Jr., Quirk, G.J., Samuel, T., Stiles, J.K., Sy, A.U., Taira, D.A., Trepka, M.J., Villalta, F., and Wiese, T.E.: Building a diverse workforce and thinkforce to reduce health disparities. International Journal of Environmental Research and Public Health 18, 1569, 2021. PMCID: PMC7915161. https://doi.org/10.3390/ijerph18041569

Abstracts/Posters: 1. Dowsett L and Maeda M. Study of the D359N mutation in IVD: a unique Micronesian variant with a mild phenotype. **Accepted to the Pacific Region Indigenous Doctors Congress, Vancouver, Canada in 2020 – postponed to 2022 due to COVID-19** 2. Nogues, Marina, Abe, Keith, Tanaka, Len Harrington John, Chang Rupert, Ching, Natascha, Melish, Marian, and Purohit. Prashant J, Therapeutic Plasma Exchange for the treatment of Super Refractory Status Epilepticus and FIRES. National Congress, Society of Critical Care Medicine 3. Nguyen D, Lau R, Kim L. Three Year Old with Proteinuria. Abstract at the John A Burns School of Medicine Annual Biomedical Sciences & Health Disparities Symposium. April 2021. 4. Saringkarisate, Kornkanok, Len, Kyra A, Melish, ME, Prothero, Bryscen K, Ching, Natascha. Neonatal vaccine-strain Varicella meningitis transmitted by maternal post-partum vaccination "Neonatal Varicella Meningitis Caused by Vaccine-strain After Postpartum Maternal Varicella Vaccination Rash," AAP September 2021. Virtual Poster 5. Saringkarisate, Kornkanok, Len, Kyra A, Melish, ME, Prothero, Bryscen K, Ching, Natascha. Neonatal vaccine-strain Varicella meningitis transmitted by maternal post-partum vaccination, John A. Burns School of Medicine Biomedical Sciences and Health Disparities Symposium. April 15, 2021

Presentations: 1. Beaty T. Update in Asthma: Practical Application for the Clinician. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. April 22, 2021. 2. Bratinscak, A. COVID-19 and MIS-C in children – CME conference (Grand rounds), Department of Pediatrics, John A. Burns School of Medicine, Honolulu, 2020 3. Bratincsak, A. Children’s Heart in COVID-19 – in COVID-19 getting back to athletics: Hawaii update; University of Hawaii, Honolulu, 2020 4. Bratincsak, A. Arrhythmias and their Management – Academy of Neonatal Nursing, Spring 2021 Virtual Advanced Practice & Low Risk Neonatal Nurses Conference, Honolulu, 2021 5. Bratincsak, A. Cardiac ECMO – Hana’uola ECMO training program at Hawaii Pacific Health, Honolulu, 2021

Department of Pediatrics, 2021 Annual Report

PUBLICATIONS & PRESENTATIONS 6. Bratincsak, A. Myocarditis associated with COVID-19 vaccine – CME conference (Grand rounds), Department of Pediatrics, John A. Burns School of Medicine, Honolulu, 2021 7. Ching N, Wasserman G, Fukuda A, and Lee MJ. Congenital Syphilis: To Treat or Not to Treat. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. August 20, 2020. 8. Dowsett L. World Stem Cell Summit Panel on Diversity, Equity, & Inclusion. Pre-recorded webinar. Guest Panelist. California Institute for Regenerative Medicine. May 24, 2021. 9. Dowsett L. Treatment & Management of Genetic Diseases. Pediatric Grand Rounds, Kapi‘olani Medical Center for Women & Children. May 6th, 2021. 10. Dowsett L. Newborn Dysmorphology, Faculty Advisor. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. February 4, 2021. 11. Edinger C, Ching N, and Bratincsak A. COVID-19 and MIS-C in Children. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. November 12, 2020. 12. Ingraham SE. Renal Tubular Acidosis: Acidic Blood and Basic Facts. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. March 11, 2021. 13. King JL, Okamoto J, Walton C, Asano S, and Doran L. The Intensive Feeding Program at Kapi’olani Medical Center for Women & Children. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. February 25, 2021. 14. Kurahara D. Juvenile Dermatomyositis. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. January 28, 2021. 15. Lynch C. The Preparticipation Evaluation and Return to Play in the Time of COVID. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. April 29, 2021.

16. Melish M. What Next? Shocks and Surprises of the COVID Era. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. May 13, 2021. 17. Park J and Bratincsak A. Myocarditis associated with COVID-19 vaccine. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. June 10, 2021. 18. Tanaka A. Abnormal Looking Movements in Infancy and Childhood. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. October 15, 2020. 19. Uramoto G. Short Stature: Growth Hormone Use and Abuse. Pediatric Grand Rounds, Kap’iolani Medical Center for Women & Children. October 1, 2020. 20. Zagustin T. Pediatric Traumatic Brain Injury, Special Considerations. Pediatric Grand Rounds, Kapi’olani Medical Center for Women & Children. September 24, 2020.

Invited Talks/Other: 1. Dowsett L. State of the Field. Papa Ola Lokahi, Webinar, Guest Speaker w/ Dr. Stacy Brown and Dr. Keolu Fox. June 12, 2021. 2. Dowsett L. Current Genomics. Papa Ola Lokahi (3/3 series), Webinar, Guest Speaker w/ Dr. Keolu Fox. November 21, 2020. 3. Dowsett L. Ancient Genomics. Papa Ola Lokahi (2/3 series), Webinar, Guest Speaker w/ Dr. Keolu Fox. October 23, 2020. 4. Dowsett L. Hawaiian Genomics 101. Papa Ola Lokahi (1/3 series), Webinar, Guest Speaker w. Dr. Keolu Fox. October 10, 2020. 5. Dowsett L. Imi Ho`ola Phase I: Pathway to Medicine, Resiliency, and Work-Life Balance, Guest Speaker. August 14, 2020. 6. Dowsett L. Ask-A-Kauka: Pediatrics in the time of COVID-19, Webinar Panelist. July 22, 2020.

Department of Pediatrics, 2021 Annual Report

WORKS CITED: Cover page (page 1): “KAPIOLANI MEDICAL CENTER DIAMOND HEAD TOWER.” PHILPOTTS INTERIORS, https://www.philpotts.net/portfolio/kapiolanimedical-center-diamond-head-tower/. Accessed 8 Dec. 2021. Page 2: “KAPIOLANI MEDICAL CENTER DIAMOND HEAD TOWER.” PHILPOTTS INTERIORS, https://www.philpotts.net/portfolio/kapiolanimedical-center-diamond-head-tower/. Accessed 8 Dec. 2021. Page 3 & 4: “Kapi'olani Medical Center for Women & Children, Diamond Head Tower Kapi'olani Medical Center for Women & Children Waiting Room Second View.” HDR INC, HDR, https://www.hdrinc.com/portfolio/kapiolani-medical-center-women-children-diamond -head-tower. Accessed 8 Dec. 2021. Page 19: Photo courtesy of Gina French, MD Page 18, 27, 32, 40: “HAWAII KAPI’OLANI MEDICAL CENTER.” LIONAKIS, Lionakis, 2021, https://www.lionakis.com/projects/hawaii-kapiolani-medicalcenter/. Accessed 8 Dec. 2021. Page 22, 29, 36,: “HAWAII KAPI’OLANI MEDICAL CENTER.” LIONAKIS, Lionakis, 2021, https://www.lionakis.com/projects/hawaii-kapiolani-medicalcenter/. Accessed 8 Dec. 2021. Page 31: Photo courtesy of Randal Wada, MD Page 35: Photo courtesy of Jessica Kosut, MD Page 42: Photo courtesy of Rhiana Lau, MD Page 57: Group photo courtesy of the UH Pediatrics Residency Program Page 61: Photo courtesy of Loren Yamamoto, MD Page 62: “JABSOM Learning Communities (2021).” Youtube, UH Foundation , https://www.youtube.com/watch?v=6CP1IicG_hA. Accessed 8 Dec. 2021. Page 91: Saemilee. “Watercolor Tropical Leaves.” Photos.com By Getty Images, Photos.com, https://photos.com/featured/watercolortropical-leaves-saemilee.html. Accessed 8 Dec. 2021.

Department of Pediatrics, 2021 Annual Report

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Department of Pediatrics 2020-2021 Annual Report

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Department of Pediatrics 2020-2021 Annual Report

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