ENCAPSULATION Neutral Pellets and Coating Polymers
Sugar Pellets Sugar Pellets Definitions: l
SPRAYSPHERES™ - SS contains not more than 92 percent of sucrose. Calculated on the dried basis. The dried basis. The remainder consists of corn starch as per the European Pharmacopoeia.
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Compliance with Ph. Eur., USP/ NF and JP.
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Produced in accordance with the cGMP.
Sugar pellets particle size specifications: Particle size distribution (analyzed by laser diffraction) shows the symmetrical character of the distribution. The single model profile, associated a very homogeneous population of SPRAYSPHERES™ - SS. Sugar Pellets Application: Used as cores to be coated in the manufacture of dry pharmaceutical / Nutraceutical / herbal / homeopathy form especially for controlled release & specially formulations. SPRAYSPHERES™ - Speciality Products (SS): Definition: SPRAYSPHERES™ - SS base of sugar & starch pellets coated with cationic polymers. Application: l
Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
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Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
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Using SPRAYSPHERES™ - SS can be converted to ready to fill pellet technology.
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Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc.
Sr. No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Grade Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS Sugar Pellets SS
Mesh Size (ASTM) 120 – 140 100 – 120 80 – 100 70 – 80 60 – 70 50 – 60 45 – 50 45 – 60 40 – 60 40 – 50 40 – 45 35 – 55 35 – 50 35 – 45 35 – 40 30 – 35 25 – 30 20 – 25 18 – 20 16 – 20 16 – 18 14 – 16 12 – 16 12 – 14 10 – 12
Diameter In mm (µm) 0,106 – 0,125 0,125 – 0,150 0,150 – 0,180 0,180 – 0,212 0,212 – 0,250 0,250 – 0,300 0,300 – 0,355 0,250 – 0,355 0,250 – 0,425 0,300 – 0,425 0,355 – 0,425 0,355 – 0,500 0,300 – 0,500 0,400 – 0,450 0,425 – 0,500 0,500 – 0,600 0,600 – 0,710 0,710 – 0,850 0,850 – 1,000 0,850 – 1,180 1,000 – 1,180 1,180 – 1,400 1,400 – 1,700 1,400 – 1,700 1,700 – 2,000
Application
Used as drug - free cores / starter cores for controlled or sustained release, immediate release, delayed release applications.
We do customized special cores / pellets for customers on their annual product requirements.
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Starch Pellets Starch Pellets Definitions: l
Starch spheres contain more than 92 percent of starch. Calculated on the dried basis. The dried basis. The remainder consists of sugar.
l
Produced in accordance with the cGMP.
Application: l
Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l
Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
l
Using SPRAYSPHERES™ - STS can be converted to ready to fill pellet technology.
l
Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc. Sr. No. 1 2 3 4 5 6 7 8 9 10
Grade Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS Starch Pellets STS
Mesh Size (ASTM) 12 - 14 16 - 18 18 - 20 20 - 30 30 - 40 40 - 50 50 - 60 60 - 80 80 - 100 100 - 200
Diameter In mm (µm) 1,400 – 1,700 1,000 – 1,180 0,850 – 1,000 – – 0,300 – 0,425 0,250 – 0,300 – 0,150 – 0,180 –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beadlets with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements.
Lactose Pellets Lactose Pellets Definitions: l
Lactose spheres contain more than 80 percent of lactose. Calculated on the dried basis. The dried basis. The remainder consists of Starch.
l
Produced in accordance with the cGMP.
l
Completely for water soluble application a substitute for sugar.
Application: l
Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l
Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
l
Using SPRAYSPHERES™ - LS can be converted to ready to fill pellet technology.
l
Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc. Sr. No. 1 2 3 4 5 6 7 8
Grade Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS Lactose Pellets LS
Mesh Size (ASTM) 18 / 20 20 / 30 30 / 40 40 / 50 50 / 60 60 / 80 80 / 100 100 / 200
Diameter In mm (µm) 0,850 – 1,000 – – 0,300 – 0,425 0,250 – 0,300 – 0,150 – 0,180 –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beadlets with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Calcium Carbonate Pellets SPRAYSPHERES™ - CS l
Calcium Carbonate Neutral Pellets consist of CaCO3 and also used for the controlled release and MUPS formulations in nutraceutical and pharmaceutical medicine.
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Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and dissolution profile.
Calcium Carbonate Pellets Definitions: l
The SPRAYSPHERES™ - CS have been developed using calcium carbonate (90%) as base and other ingredient is maize starch.
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Calcium carbonate complying with Ph. Eur / USP / NF.
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Manufacturing in accordance with the cGMP.
Calcium Carbonate General Properties: l
Nearly white hard, uniform and spherical particles. (sphericity degree average >90%)
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Very low friability level.
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Calcium carbonate high physiochemical inertness improves the stability of the finished product.
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Uniform and consistent loading.
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Calcium give a improved taste and mouth feel for the pellets.
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For PH dependent applications
Calcium Carbonate Particle Size Specifications: l
Minimum of 92% (w/w) of SPRAYSPHERES™ - CS are between the lower and the upper limits of the size stated on the label.
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The SPRAYSPHERS™ - CS selection is obtained by the decreasing size by sieving method.
Calcium Carbonate Application: l
Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and coating.
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Suitable for non-carcinogenic products.
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Ph controlled applications, these starter cores give a specific ph to the dissolution profile.
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Adopted to controlled release or sustained release formulations SPRAYSPHERES™ - CS make it easy to produce spherical micro granules which have the most suitable size and dissolution profile to each specific purpose.
Sr. No. 1 2 3 4 5 6
Grade Calcium Carbonate Pellets CS -100 Calcium Carbonate Pellets CS-102 Calcium Carbonate Pellets CS-203 Calcium Carbonate Pellets CS-305 Calcium Carbonate Pellets CS-507 Calcium Carbonate Pellets CS-708
Particle size range (µm) 75 - 212 106 - 212 150 - 300 300 - 500 500 - 710 710 - 850
Diameter In mm (µm) – – – – – –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beads with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements.
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Tartaric Acid Pellets SPRAYSPHERES™ - TS l
Tartaric acid pellets and also used for the controlled release and MUPS formulations in nutraceutical and pharmaceutical medicine.
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Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and dissolution profile.
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Tartaric acid complying with Ph. Eur / USP / NF.
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Manufacturing in accordance with the cGMP.
Tartaric acid General Properties: l
Very low friability level.
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Tartaric acid high physiochemical inertness improves the stability of the finished product.
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Uniform and consistent loading.
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For PH dependent applications
Tartaric acid pellet Application: l
Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and coating.
l
Suitable for non-carcinogenic products.
l
Ph controlled applications; these starter cores give a specific ph to the dissolution profile. Sr. No. 1 2 3 4 5 6
Grade Tartaric Acid Pellets TS Tartaric Acid Pellets TS Tartaric Acid Pellets LS Tartaric Acid Pellets TS Tartaric Acid Pellets TS Tartaric Acid Pellets TS Tartaric Acid Pellets TS
Particle size range (µm) 20 / 30 30 / 40 40 / 50 50 / 60 60 / 80 80 / 100 100 / 200
Diameter In mm (µm) – – – – – – –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beads with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements.
Mannitol Pellets SPRAYSPHERES™ - MAS Manitol Pellets Definitions: l
Manitol spheres contain more than 80 percent of Manitol. Calculated on the dried basis. The dried basis. The remainder consists of Starch.
l
Produced in accordance with the cGMP.
l
Completely for water soluble application a substitute for sugar.
Application: l
Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l
Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
l
Using SPRAYSPHERES™ - MAS can be converted to ready to fill pellet technology.
l
Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc. Sr. No. 1 2 3 4 5 6 7 8
Grade Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS Mannitol Pellets MAS
Mesh Size (ASTM) 18 / 20 20 / 30 30 / 40 40 / 50 50 / 60 60 / 80 80 / 100 100 / 200
Diameter In mm (µm) 0,850 – 1,000 – – 0,300 – 0,425 0,250 – 0,300 – 0,150 – 0,180 –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beadlets with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Silica Pellets SPRAYSPHERES™ - AS Silica Pellets Neutral pellets Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPS technology. Silica Pellets Definitions: l
The SPRAYSPHERES™ - AS have been developed using Silicon dioxide (< 75%) as base.
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Silica complying with Ph. Eur / USP / NF.
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Manufacturing in accordance with the cGMP.
Silica Pellets General properties: l
Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)
l
Very low friability level.
Sr. No. 1 2 3 4 5 6
Grade Silica Pellets AS-100 Silica Pellets AS-102 Silica Pellets AS-203 Silica Pellets AS-305 Silica Pellets AS-507 Silica Pellets AS-708
Particle size range (µm) 75 - 212 106 - 212 150 - 300 300 - 500 500 - 710 710 - 850
Diameter In mm (µm) – – – – – –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beads with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements.
MCC Pellets SPRAYSPHERES™ - MS Microcrystalline Cellulose Pellets Neutral pellets for sugar free products, highly soluble & controlled released formulation products. MCC Pellets Definitions: l
The SPRAYSPHERES™ - MS have been developed using microcrystalline cellulose (MCC) as base.
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Microcrystalline cellulose is purifies, partly devolymerised cellulose, prepared from alpha cellulose.
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MCC complying with Ph. Eur.
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Manufacturing in accordance with the cGMP.
MCC Pellets General properties: l
Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)
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Very low friability level.
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MCC high physiochemical inertness improves the stability of the finished product.
l
Insoluble in water, absolute ethanol, acetone. Sr. No. 1 2 3 4 5 6
Grade MCC Pellets MS-100 MCC Pellets MS-102 MCC Pellets MS-203 MCC Pellets MS-305 MCC Pellets MS-507 MCC Pellets MS-708
Particle size range (µm) 75 - 212 106 - 212 150 - 300 300 - 500 500 - 710 710 - 850
Diameter In mm (µm) – – – – – –
Application
Used as spherical seed cores for drug layering & film coating. Also used in manufacture of granules / beads with sustained / controlled release, taste masking & other special properties.
We do customized special cores / pellets for customers on their annual product requirements. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Acrylic Coating Polymer
STOMACH PH 1- 1.5 DUODENUM PH > 5.5
SPRAYPOL E 100
SPRAYPOL L 30 D-55
SPRAYPOL EPO
JEJUNM PH 6-7 SPRAYPOL L 100
COLON ASCENDENS PH 6-7 SPRAYPOL S 100
TIME CONTROLLED SUSTAINED RELEASE IIEUM PH UP TO 7.5 SPRAYPOL S 100
L - 30 D - 55 Application: Drug delivery in Jejunum. Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.
E - 100 Application: Taste and odour masking, insolating coating, transdermal applications, moisture protection. Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.
EPO Application: Taste and odour masking, Insolating coating, transdermal applications, moisture protection. Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.
L - 100 Application: Drug delivery in Jejunum. Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.
S - 100 Application: Drug delivery in Jejunum. Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups. Sr. No. 1 2 3 4 5
Neutral Excipients Spraypol L-30D-55 Spraypol E-100 Spraypol EPO Spraypol L-100 Spraypol S-100
Percentage (%) 30.00% 100% 100% 100% 100%
Therapeutical Polymer for enteric coating Polymer for enteric coating Polymer for enteric coating Polymer for enteric coating Polymer for enteric coating
PH Release PH 7.5 - 5 PH 1 - 1.5 PH 1 - 1.5 PH 6 - 7 PH up to 7.5
We do customized Projects / Development for customer based on their annual requirement of the product. Pellets from 50 - 2500 micron sizes possible. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.
Umang was incepted in the year 1982, with an objective to serve the clients with all kinds of equipments and accessories under one roof. Within a very short span of time, we succeeded to be the most reliable brand name in the market supplying equipments and solutions to the Pharmaceutical industry for Pelletization and granulation solutions. In 2007, the company ventured into solutions for Personal care industry majorly focusing on Oral care products, giving encapsulated ingredients for cooling applications. In 2009, the company further integrated itself to give solutions for Bakery and food applications like Chewing gum, mouth dissolving films etc. Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development like geletain beads, Edible films, innovative encapsulation applications.
Pelletization and Edible Film Solutions
Concept Range
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Websites: www.umangpharmatech.com www.umangengineering.com www.extruderspheronizer.com
Websites: www.concept-machines.com www.coating-machines.com
Personal Care and Detergents
Bakery and Food Decoration
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Websites: www.umangpharma.com www.cosmeticbeads.com
Websites: www.umangpharma.com www.edibleglitters.com www.ediblefilm.co.uk
Pharmaceutical and Nutraceutical
Neutral Pellets and Coating Polymers
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.
Websites: www.umangpharmaceuticals.com www.pharmaceuticalpellets.com www.pharma-spheres.com
Websites: www.umangpharmaceuticals.com www.micro-pellets.com www.pharma-spheres.com
Umang Pharmatech Pvt. Ltd.
A truly global organization...
Survey No. 146, H. No.1 (PT), Vasai Phata Highway Junction, Pelhar, Nh8, Vasai (E) - 401 208, Maharashtra (India). Tel. : (+91-22) 30018900 / 30018915 - 98 Mob. : (+91) 986 723 6594 Fax : (+91-22) 30018908 / 30018913 E-mail : umang@umangpharmatech.com
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