Leading the Way Through Research During Uncertain Times

Leading the Way

Through Research During Uncertain Times

In the early stages of the pandemic, EIOH experts made efforts to assess all the available evidence at the time and determine the potential risks of practicing dentistry during the COVID-19 pandemic.

“Dental Care and Oral Health under the Clouds of COVID-19,” published in April 2020 in JDR Clinical and Translational Research, continues today to be the most cited and most read article, having been downloaded more than 13,000 times. Authors Drs. Ren, Rasubala, Eliav and Malmstrom wanted to address the confusion and anxiety early in the pandemic’s cycle when emergency-only dental procedures were allowed in the U.S. Thoroughly examining the available data at the time from oral health providers around the world, the piece explored the oral health implications of the virus, transmission, provision of care in a safe environment, and provided recommendations.

The next paper, “Risk for dental healthcare professionals during the COVID-19 global pandemic: An evidencebased assessment” was published in July 2020 and also topped the list as most widely read and downloaded in the Journal of Dentistry, the leading international dental journal within the field of restorative dentistry. It is also among the top three of the Journal’s articles that received the most social media attention during the pandemic.

“We found that the risk of COVID-19 transmission in dental offices is extremely low if the CDC guidance is followed,” said Yanfang Ren, DDS, PhD, MPH, EIOH professor, whose research has been widely cited throughout the pandemic. “Recently published data also shows that the risk for dental professionals to contract COVID-19 is not higher than the general public.”

The article was available shortly after many dental offices re-opened for elective and routine procedures. The authors, Drs. Yanfang Ren, Changyng Feng, Linda Rasubala and Eli Eliav, concluded that the risk of COVID-19 transmission in dental offices is very low based on available evidence on effectiveness of PPE and prevalence of asymptomatic patients.

With emerging evidence that COVID-19 might be transmissible via airborne aerosol particles, EIOH’s research is now focused on aerosol removal from dental offices by ventilation, air filtration and source controls.

The studies, published in the Journal of Dentistry, have showed that aerosol particles will accumulate in dental treatment rooms with a low ventilation rate (less than 6 air changes per hour), and that a portable air cleaner with high efficiency particulate air (HEPA) filter is effective in reducing aerosol accumulation and speeding up aerosol removal.

“We also found that carbon dioxide levels in dental treatment rooms are directly associated with ventilation rate and the number of people in the room,” Dr. Ren explained. “We have developed a protocol for dental practitioners to conveniently and accurately assess the ventilation rate of their treatment rooms by observing the CO2 levels after a simple mixing of household baking soda with vinegar.” This study has been accepted in the Journal of Dental Research.

Today, Dr. Ren and his team are continuing to study aerosol behavior and aerosol control from dental offices in collaboration with University of Rochester mechanical, chemical and building engineers to better understand the risks related to dental aerosols and to assess the effectiveness of different equipment for aerosol removal from dental offices.

JDR Clinical & Translational Research – April 2020

Dental Care and Oral Health Under the Clouds of COVID-19 Invited Commentary Authors: Drs. Ren, Rasubala, Malmstrom, Eliav

World renowned aerosol scientist Linsey Marr, PhD, cited EIOH research in her recent lecture.

Dr. Yanfang Ren (standing) mentors AEGD residents Tamer Marzouk (left) and Qirong Huang, as they gather data about aerosol behavior during dental treatments.

Quintessence International – May 2020

Dental Care During the Coronavirus Disease 2019 (COVID 19) Outbreak: Operatory Considerations and Clinical Aspects Authors: Drs. Abramovitz, Palmon, Levy, Karabucak, Kot-Limon, Shay, Kolokythas, Almoznino

Paedodontic Society of South Africa, Johannesburg, South Africa – June 2020

Challenges and Opportunities – Dental Care and Oral Health under the Covid-19 Pandemic. PSSA June CPD Series - Session One. Dr. Yanfang Ren

Journal of Dentistry – July 2020

Risk for Dental Healthcare Professionals During the Covid-19 Global Pandemic: an Evidence Based Assessment Authors: Drs. Ren, Feng, Rasubala, Malmstrom, Eliav

IADR/AADR – July 2020

Scientific Basis for Delivering Oral Health Care During COVID-19. IADR/AADR COVID-19 Webinar Series.

Royal College of Surgeons in Ireland – October 2020

Delivering Oral Health Care During COVID-19: Risks and Opportunities Faculty of Dentistry Annual Scientific Meeting. Dublin, Ireland. Aerosol Removal from Dental Treatment Rooms. Authors: Drs. Ren, Huang, Marzouk, Richard, Pembroke, Martone, Venner, Malmstrom, Eliav

Tenth Annual Delta Dental of Virginia Oral Health Endowed Lecture – January 2021

The Role of Aerosols in the Transmission of Covid-19 Linsey C. Marr, PhD, Renowned Aerosol Scientist EIOH’s Dr. Ren’s research was cited during Dr. Marr’s lecture

Medrxiv.org

Ventilation Rate Assessment by Carbon Dioxide Levels in Dental Treatment Rooms Authors: Drs. Huang, Marzouk, Cirligeanu, Malmstrom, Eliav, Ren

Medical Dialogues – February 2021

Addition of PAC with HEPA May Prevent COVID – 19 Spread In Dental Clinics: Study Article by Dr. Nandita Mohan citing EIOH research

Journal of Dentistry – December 2020

Effects of Mechanical Ventilation and Portable Air Cleaner on