CoHP Research Accomplishments

BY THE NUMBERS*

Center For Muscle Metabolism And Neuropathology

The Center for Muscle Metabolism and Neuropathology (CM2N), created by Dean Stephen Alway in 2019 and located within the CoHP Division of Regenerative and Rehabilitation Sciences, focuses on research that impacts human muscle function and movement. CM2N’s overarching goal is to provide the fundamental basis for novel strategies that enhance independence across the age spectrum, with current research programs comprising muscle regeneration from damage, sarcopenia and aging, cancer therapeutics and survivorship, and the impact of stroke on mobility and movement.

Cm2n Accomplishments

James Carson, PhD, division chief of Regenerative and Rehabilitation Sciences and senior associate dean of Research and Graduate Studies, is conducting an NIH NIAMS-funded study to determine mechanisms of bone muscle crosstalk that can accelerate muscle mass recovery after periods of forced disuse.

• The four faculty members currently associated with CM2N have secured four federally funded grants from the National Institutes of Health and the Department of Defense as principal investigators.

• CM2N faculty have published over 38 referred research papers since 2019.

• Currently, Dean Alway is leading a Department of Defense-funded project examining mechanisms to improve muscle regeneration from injury.

• Dr. Alway and Dr. Carson also collaborate on NIH-funded studies in the Department of Anatomy and Neurobiology and the Department of Genetics, Genomics, and Informatics, examining genetic factors contributing to functional deficits with aging and Alzheimer’s disease.