Fitzpatrick's 2008 - Part 08 - The Skin In Systemic Disease

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  

Copyright ? 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.

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                                                                                                                                 

 

                                                                                                                                                                                 

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                                  

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                                                                                   





                                                                                                                                                                                                                                                     

                                                                                                                                                                                     

                                                                             

     

       

    

                                                                                                                                                              

                                                                                                                 

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                                                                             

                                                                          

  



                                                                                                                                                                                                                                 



          

                            



                                                                                                                                                                          

                                                                                                                                  

                                                  

       

       

                                                                                                                            

                                                                                                                                                                                     

                                                                                                                      

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                                                                                                                    



                                                                                           

                                                                                                                                                                                                                                                                   

                                                                                                                                                                                                                                       

                                                                                                                                                                                                                                      

                                                                                   

                                                             

                                                                          

                                               

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                                                                                                                                                                                           



                        

                                                      

                                                                                                                                             

                                                                                                                                                                                                                                           

                                                                                                                                                                                                                       

                                                                                                                                                              

            

                                                                                                                                                                                                                                           

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                                                                                                                                             

                                                                                                                            

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        

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                                                                                                                                                                         

                                                                                                                                                                                                                                                     

                                   

                       

            

                

                                                                                                                                                                           

                                                                                                                                          

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

                                                                             

                                     

                                                                                                                                                                

                                                                                  

                                  

                                                     

                                                                                                                                                                                           

                                                                                                                                                                                                                                   

                                                                                                                                                                                  

                                                                                                                                                                   

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                                                                                                                                                          





                                                                                                                     

                                                                                                                                                                                                                             

                                                                                                                                                                                                                                                                 

                                                                           

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                                                                                       

                                                                                                               

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    

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                                                                                                                                                



                                                                                            

                                                                                                                                                                                                 

                                                                                                                                                                                                                                           

                                                                                                                                                                                                                         

                                                                                                                                                                                               

                                 

                                                                                                                                                                                                                                                         

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                                                                                                                                                         

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                                                                                                                                                                                

            

                                                   



                                                                                                                                                              

                                                                                                                                                            

    







  



 

 



 

    





    





 





 

   







 

 





     

 



  









 

 







 

 

  





  

  



   













                                                                    

                                                                                                    





                                                                                

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

                                              

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                                                                                                                                                                                

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 

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                        

                      

                                                    

                                         

    

 

 

 

   

 

 

   

 

 

 

 

   



                                                                                                                       





                      

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









                          

                                                                    

                                                           

                                                                 



  

 

                      

             

                                             

                                     

                                                                                                                                                          

                                  

                                                

                   

                                                                       

                 



                     

                               







                                                                           

                             

                                                                                                                                                     

                          

                                                    

                                                       

                                 

                                                         

         





    

 

  

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                          



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 





    

  

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   

   



  



    

                                                                                                         

                                                                                          

                                                                  

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                                      



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                                                                                                                                                                              

                                                                                                                                                                                                           

                                                                                                                                                                          

                           

                                                                                                                                                               

                                                                 

                                                               

                                                                               

                                                  



       

       

          



 

                                                                                                       

                      

   



                     



                                                                                                                                    

                                                           

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                                                                                                                                                                     

                                                         

                                                                                    

 

  

  

    

        









     

     

     

     

       

     

      

     

    

   

  

 

   

   

 

 





  

 



 



 

 

 

 





 

 

   

  

 

   

 

 

 

   



                                                                  

   





 

 







  



  













 



 













 

                                                                                                                    





                           

                                                                                                                                                             

                                           





                                                                  

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 



 

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    

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    

 

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  

 

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  

                                                                                

                  

                         

                                             







 

 







  







  



   

     



        

                    

  

 









  

 

   

   

 

   



   

               

               

                                                                                                                               

                                                                               

                                                                                                                                             

  

                                                                                                                                                        

                                                                                                                                                             

   







      

      

      

      

    



                                                        

                                                                                                       

    



        

 





 





















 





   

 



  



   

                                                      

     

                                                                        

 

  

    

 

  

 

   

         



   

  

   

 



   



             

  

 

                                                                       

                     

                                                                            

  

 

 

 



 

 

  

 



 









 

 

 







 

 

 



  

  





  

  

  

  

  



 



               



                                                                                                                

                                                                                                                                                                                                                                               

                                                                                                                                                                                   

                    

                                                                                                                                                                                                                                   

                                                                                                                                                                                                                      

                                                                                                                                                                                                                                



                                                                                             



                                                                                                                                   

                                                                      

       

                                                                                  

      

                                                                                                                                        

                                                                                                                                                                                                                                                                               

                                                                                                                                                                                                               





          

  

  

 

 



































































































































































 

















































 





























  







  





















  

















     

                                                                                                                                                                                                                 

                                                

                                                          

    

 

  

 

                        



                                            



                                                                                                                                                                                                            

                                                                                                                                                                                                                         

  



           

                                                                         

                                       

                                                                                                                                                   

                

                                                                                             

                                                                                         

  



            

                                    

                                                                     

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                                                                                                                                                                            

                                            

                                                                                                                                               

                      

                                   

                                                                                                                                                                                                                                            

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                                                                                                           

                                                                                      

              

                 



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                                                     



    

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                                                                                                                                   

                                                                         

                                                                                                                                                                                                                                                                      

                                                                                                                                                        

                                                                                       

  



             

                                                                                                                            

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      



                                                                                     

                                                                                                   

                                                                                                                           

   



 

 





  

















 





 



  

 

 







  





 



  





                                                                                                                                   

  

           

                                                                                                                                                 

                                                               

  

        



                                                                                                                           



                                                                                                                                                    

                                   

                               

                                                                                     

                                                                                                                                                                                                                               

                          

                     

                                                                                                                                         

         

  

                     

                                                                                                              

       

              

                                                                                                                                   

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                                                                                                                                                                                    





 

                    

 



                                                                                                                                            

                                                                                                                                                                                                                                                             

      

                                    

             

                                                                                                                                                                                                                  

                                                                                                                                       





                                                                                  



  

             

                                                                                                               



                                           

                                                                                                                                                                 

                                               

    

        

                                                                                                                                           

              

                                                                              

                                                                                                                                 

 

 

 

 

 

 

 

 

 

                                                                       

                                                              



                                                                

                                                                                                                

 



                                                   

                                                                  

                                                                                                                  

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 

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                                      

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                                                                                                                                                                                                                                                                       

             

                                                                                                                                                       

                

                                                                                                                                            

                                                     

                                 





                                                                          

                         

       



  









 



 

 

 





 





 





 





 





  





  





  





  



 

  

                                                                                                  

                                                                                             

         

                





                   

                

          



                                            



 

  

   

 

 







    

   





   

  

   

 

   

   

   

 

 

 

     





 

 

 

  

 



 

 







 

 

 

      



      

    



  



  



 

  

  

  

   

 

  

 

 





               



                                   

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

                           

                             

     

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                                                         

                                                                        

                                                                                             

                                         

                           



                     

                                             







   







                                                   



 

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  

                                                                                       

            

                                 

                                                                             

  



                      

                                              

                                 



             

                                          

           

                 

                    





                                 

                       

                 

                                                                         

                                                                          

                                                                                                                    

                                                              

                                                         

             

            

 



     



                  

          

                                                                                          

                                                

                                                                                                                      



           

                                                                     

                                                                            

                                          



  

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                                            

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                                                                                                                                             

                                                                                                              

                                     

                                                                

                                                             

                                               

 

  

 



    

















 

 

  

  

 

 

 



  

  

  





 





 











 

 

 

  

  

  

 

 

 

  

 

 

  

  



 







  

  

 



  

  

  

 





   



 

 



 

 







 

  



 

    



 



 

 





  

    

 

 

 

 

   



  

   

    

     

      

                                      

                                                            

     

 

                      









 

                                                                        

                                                              

                            



                                                                                                                        

                                                           

                           

                                    

       

                             

                                             

                                    

  

                                                                                                                                                                                                  

                                                        

                                                                                                                        

                

                             

                  

                           

       

                        



        

                                                                              



                                                                                   





                   

 

                                                                                                                            

                         



   

     

                                                    

                                               



                    

                                                                                                                                                                           

  

                                     

       

                                                                  

            

                                               

                      

       

                 



                                                                                    



            

                                                                                                         





                                       

              

      

                                                                  

                                                                      

          

  

    







    

     



  





    

  

  

     

   

   

    

      

 

           

      

                                                                                                                                            

    



                                                                          



  



 

                                                                              

        



                                                     

                                  

 

                     

  

                                                                               

                                       

                                                

                                                               



     



                 

                                                         



  

                                                                                                                                                                                            

    



         

     

                                                     



                                                                                            



                                                     

                                        

                                                                  

 

         



    



                          



                                                                   

                                                                                                   

 

                       

               

      

           

                                                                     

          

        

                                    

                    

   



 











    

  



 





 













                                                                                           

                  

                                                                               

                                           



                              

                                                                 

                 



                   

                                  



                                                         

                        

                           

                                  

                                 

              

       

           

                                                

                                                             

                







 

 

                   

                                                                                                                                                                                    



                                                                   





                             





 











 





             



       

                   

                                                                                             

 



 

 



   

    

 

  



 

  

   



                

    





                                                 

                                        

  

          

                             

                               

             



                                         

                                                                                 



                   

      

 



 

                                                                       

                                                                 

                                                                                                                         



 

                                                                         





                                                                                   



 

                                     





                                              

          

                                                                                     



 

                       

                           

                                                                          

                                                                                           



  



















  

    

  





   





  

 

   

 

 







 







 

 

 



 

  







 

  



   







    

  



 

 

 

 



 

  

   

 

 



 

  

 

  

 



 

   

   

 





 

    

       

 

  





  



 

 



 

  

  

 





 

   

 

 

  



 

    

     

  

  

       

 

    

   

       

                                                          

                

                             

                                                  

                                                                                                                             

                                      

                                           



                                                                             

                         

   



                                            

                                       

                                                      



               

                                                                                

                                                                                                                                                                                

                                                                                                 

 



                                                      

                                                  

                                                                         

                                                                                   

                                                                                                                                                                                          

                     









 

 

     





 

 

              



                                                   

                                           

                                                                                                       

   

                                                                                                                                                                      

                 

                

                                       

  

                 





   



   

                        

               

                                                                        



        

                       



                                                                         

                                              

                                                                                                                                   

                                                                                                                                                                                                         

        

 



         

                                                                                                                                                              



         







                                                                                                                                                                                                          

                     

                                                                                 

                  

                                                                                                                                            

                                                                                                                              

                                 

                                                                                                                                                                         

                                                                                                                                

                        

                



     

  



     

                      

                                                                                                              

                              

 

      

                                                                                                                  

                                                                       

            

                                              

                                                                               

                                                                                                    

                      

                                                                  

                                                                       

                                      

                     

                



                                                                           

                                                                          

                                                                                         



 



                 

            

                                                                                                                                                            

                                                                                                  

  









 



 







  



 





 

 







 



 



 





 





 



 

                                                                        

                           

                            

                                                                                                       

                                                                                                   

    



                 

                                                                                                 



                                                                                                     

                                      

                                                                                                                                                                              

                                                                                                                          

                          

                                                                         

                                                                                                 

                                                                                                                                                           

                                                                                                    

          

                              

                                                                                                                       

                                                                              



                                                                                                                                                             







             

                       

 

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                                                                                                                                                                                                                              

                                                                                                                             

                                                                                                                                                                                                                                            

                                                                                                                              

                                                                                                                                                                              

           

                  



                                     



                       





                                                                                                                                         

 

                                                                                                                                                      

                                                                                 

                                                                                                                                          







          

 

  



                                                   

                                   

  

                                                                                                                                

                                                                                                                                                  

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

                                     

                                                                                                                  

                                                                                 

 













 

    

  

   

 

 

   

    

  

  

 

      

 

    

    

 

    

     



     

 

 



 

  

 

  

  



    

                                                                                                                                                                                                  

  



       

         

   

 

                                                                                                                                                

        

                          

                                                                                                                                  



                                                                                                       

 

 





                                                                                                     

 



                                                                                                                    

                                                                                                                                         

                    

                                                                                                                                                                                                                                             

  





 

 

 



 

 



  

        

  

  

                                                                                                                                    

                                                                    

                               



 



                                             



         





                                                                                                                     

                                                                       

                                        

                                                                                              

                                                                                                  

           



                  

                                                                                                                            

                                      

                                                             

                                                                                                                                                                      

    

 

 



               

                            





    





         













   

 

 

  

    

 

  

  





      

 









 





   



  



  

 

 

 

   

 

   

       



 

 

          



    

   

 

     



 

     

 

  

    

  

 

  



     

  

 

 

  

 

  





 



 

  

 

 

    

 





 

   

 

       



   

 





 

 

      



 

  

 

  

  

 

    



       







    

















 





     

 

    



   

 

 

    

   

   

   

  

      

 

   

  

 

 

     

 

 

   

 

 

 



  

 

 

                                                                                                                                                       

                                                                                                        

                              



                                                                            

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                                                                                      

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                                 



     

          

                                    

 

 

   

        

                                                                                                                                                                                                                              

                                                                                                                                                                                                                   

                                                                                                                                                                                                  



                                                                                                                 



                                                                                                        

                                                                                                                                                                                      

                                                                                                              

            

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                        

                                    

                                        

                                                                                                  

   

    

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           

   



                                       

                                                         

                                                   

                                                 

                                                                 

                                                            

                                                                                                                                                                       

                     

       

            



                                                                                                                                                             

 

                            

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             



                                                    

                                                                  

                                                              

                                                             

                                                                                                                        

                                     

                                                                                              





                      

                   

                                                                                                                                                                    

                                                                    



                              









                                         





 

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            



                                           

                                                                

                                                                                                   

                                                                                                                                              

                                                       

                                                                                                                               

                                                                  

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                                                                                                                                      

                                                                  



      



  



                 

        





                                                           

 

                                                                                                                                   

                                                                                                                                                                                           

                                                                                          

                                                                 

                                                                                    





                                                 

              

            

                                                                         



                      



                            



   

                                   

             

                                                                

      

                                                                             

                                                                               

      

          



 

                                                                                                        





                                                            

                                        

                               

              

                                 

            

            

         

                                                                      

                                   

                                             

                                                                                

                                              

                                        



                               

                                       



                                                                                                     

                                                                                              



 



                                         

                                          



                       

                                                                                                                                                                                                         

                                                                                                                                                    

                                                            

       

                 

                                                                                

                   

                                                                     

                                                                                       

                                                      





                

   

          



 

                                                                                                









                   

                                                                                                                                                                                  

                                                                                                              

    

                                                                                                  

                                               

                                    

                                                                                          

                                                                                                                      



 

                          

                                                                                                                                                                                                    

 

                                                       

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                                                                           



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                                                                                                                                                          

                                                                                                                                                                                                                                                    

                   

                                                                                                                     

                                                                                      

                                     

                                                                                                                             

                                                                    

                                                                                              

                                                                   

                                                                              

                                          

                                                                                                                                    

                  



                                                







                                                                                                                                                                                    

                   

               

                                                                                                           

                                                         

                                                                                                     

                                                                       

                                                                           

                                                                                                             

                                



                   

                                              

    

   

                                                                                   

 



              

       

                              





 



   

  



        

  

    



                                                                                                                                                             

                                                                           

                                                                                

                                                                                                                                                           

                                      







                          

  

                                                                             

                                      

                                                                           

                                                          



                                     



             

         

     



               

     

  

            

                                                                                    

              









             

                                                                                            

                                     

               

                                             

               

    

            

                        

                                                                                                                                                         

                    



     

                           







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

                        

                                                                                           





                                                   

                                                 

                         

   



                                                                                         

        

               

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

                                                                               

                                                                                     





                                 

                                      

                                                                                                                 



                               



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



                                  

        

      

 



 

                    







       

     

          

   









                   

       

                                             

                                                                                                                                  

          

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       

                                  

                     



                                            

                                                            





                    

               

     

                             

                                                                                                                              

                                                                                            

 

                                          

  

        

   



 



 

 

     

                                                

         

 



               

                                                 

 

  







           

  



  

         



  



   

   

 

   

 

 

 

 









  

 



  





   



          

       



   





  



 

  

 



     





  











  

  





   

 

 

 

 







  

  

     

 

 

 





                                                          

                                

                                                         

                               

          

  



           

                                                                                                                                

    

 

  

             

                                                                                                                                                       

                                                                                                  

   

            



                                                                                                                                                                                        

 



   

                                                                                                                                                        



                                                             

  



            

                                                                                                                           

  

 





 

 

    

 

 





  

   

 

 





    

           

    

     

              









 

   



  

  

 

   











 

  



                                                                    

                                                                     

            



                         

       



                                                                                                                                                    

                                                                                           

                                                                                  

                                                                

                    

  



             

  



                                                                                                                

 

                       

                                                                                                                                                     

       

                                                                                                                                     

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                                                                                                 



                                                      

                                                                                                                                                    

                                                                                                 

   

                                                                                                                                                                     

  







    

  

  

     

  





 

    







          









       

   

  

 

 





  

   

 



     

   



 

     

                                           

                              

                                             



                                                                                                                                                                                                 



                     

                                                                                                                           

                                                                                        

   



                                                                                                                                                    

                                     

 



                                                                                                                                                                    

                                                                                                                                   

            

                                                                              

           



    



                                                                                                                                                    

                                                                                                                                                                                                                                            

                                                                                                                                           

                         

                                         

                                                                          

                                       

  

            

  









 







 

 

 

 





     

    







  





   

   

  





           

 











    

    

        



 





                     



                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                    

                                                                                                                                                                                          

                                 

  



  



    

     

 



     

  

                                                                        

  



                                                                                                       

                                                                                                                                                                

         

                  



     

                                                                                                 



                                                                                              

  

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                                                                                                             

                                                                                                                                                             

                                      

           



                                                                                                             

       

                                                                                                                                                                                                                                   

 



               

                                                                                                      



  







 





 

  

 

   

    

    

  

 





 

 

  

      



    

 



 



  



 





 

 

  





 

 

 





 

 













      



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                                                                                                                                                                                                                    

                                                                                                                                        

 



                                             



 

  



 

 



 

             



                                                                                                                                                           

 



                                                                 

  

          

                                                                                                                                                                             

                                               

                                                                                                                                                                                                     

  









 



 







 

 



 

             





 

      

 



 





 









  





    



  

 

    

  

                                                                               

                                                                   

                                                                                                                                                                



                                                             

                                                      

   



                                        

                                                  

                                                           

                     



                                                                                                                                             



                                                                                                                                                

 

  

                                                                                                                                      

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                                            

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                                                                               



                                                                          

                                                                                

                                                                     





                                                                              

             



     

                                                                                   

                                       

                             

                                                                                                                                                                                                                

                                                                                                                                                                                                                                          

                               

                      

                                                                   



 

             



                                                                                                                                                                    

                                                                                                                                               

                                                                                        

                                                                                                                                               

                                                                                                                                                                                                           

                                                             

                                              

   

                      

 

                                                                                                   

                                                                                     















 



 





 

 

   





 

 







    



 

 



   





 

 







 

   

   



 



                         

                       

                                 

                                                                               

                                                        

                                           

                                                                                                                                                                                                        



  



                                                                                      

                                                                                                                                                                                                                                              

                                                                                                                                                                       

                         

                                                                                                                                                                               

                                     



                                                                                          



            

                                                                                  

      

                                                                           

                   

                                        

                                       

                                                                                           

                             



         



    

                                

                   

 

                                                                                                   



                                                                                                                                                            





          

           

                                                                                                                                                                                                                                                 

 



                                                                                                         

                                                                                  

                    

                                                                                                                                                                                                                    

                                                                                                                                                                                                                                           

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                                                                                                                                                                                                         



    

                   

                                            

          

                                                                                                                                                                         

 

   

                                                         

                                                             

                                                            

      

     

  

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                                                     

                                                  

          

          

                    

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 

     

                                            

           

            

                                                                    

                                                                   

                                                                                     

  



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                                

                             



                                                                               

           

                                                                                                                                                                                                             

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                                                               

                                                                                         

                                                                                                                                             

               

    

       



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             

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                                                                                             

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                                              

                           

                                                           

                             

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  



                                                             

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                

       

                              

                                      

                                                                                         

                                                                                                          

                                                                                                                                                  

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                                                                                                                      

 



                                                                                       

  







      

      

      

      

                                                                                                                                                                       

                                                                                                                                                                                     

                                                                                                                                                                          

                                                                                                                                                                                                                                                                       

                                                                                                                                                                                                                               



                                                                                                                                            



                                                                                                                                

                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                    

                                                                                                                                                                                                                                                               

                                                                                                                                                                                                                                                                                    

                                  

                                                                                                                                                                   

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

                                    

                      

 



                   

                                                                                                   

                

                                                                  

                                                                                                                  

                                                           

       

                                                                         

                                                                                                                                                      

           

 

                                                                                                                                                              



 



                                                                                                 



    



                                                 

                                                                                                                                     

                                                                                                                                  

            

                                                                                                                      

 

                        

                               

  



                                      

 



  

 

 







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







 













 





 

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



 



 



 

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                                                                            

                                                                   

            

           

                                                         



                                                                                      



  

                         

                                                                                               

 

                                                                                        

             

                                                                                        

  

                                                                                                                                                          

                                                                                         

                                                                                                                          

  



                                                                                            

                                                                                                   

                                                                                            

                                                                          

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

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              

             

                                                                                                                                                                                                                                                          

                                                                                                                                  

                                                                              

                                                                                                                                                                                                                                                                



                   

                         

                                                                      

                      

                              

  

                            

       

                                                                                                                                                       

                      



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

    







                                                                                                                              

 

 

     

     

     

         

                                                                     

       

   

              

                                                 

                                

                              



                      

                    

          

                                       



                       

                                                                                                                     

                        



 



             



        

                                                           

              

            

              





                

              







                                                                           

                                                                                                                                                    

                                                                                        

                                               

             

                              

                                                   

       

 

     

                                  

                                    

                                            

  



       

  

                                                          

                                

           



  

         

                                                        

        





                                           

                      

           

 

                                   

              

     

                                                           





 

 

   

     

         

 

                                                                                                       

                                                                     

                

            

        

               

             



                                                                                                                                                                     



                                                             





                                                                                                                                              

                                                                                                                



                                                                                    

  



                                                                            

                  

      

               

                                                                                                 

                          

                                                



   



  



    

      

                   



 

 

 

  

 

    

  

  

 





  

  

 



  



                                                                                                                                                                                                                                               

        

                                 

                                                                                                                                                 

                                                                                                                                                                                                                                          

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   

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    

                                                                     

                                                                                                                                                                                  

             

                 

                                                          

              

       



                                                                        



                                

                                                                                                                        

                                                                                                                              

     

                       

  













































     







       

                                                                                                       

 







 



  









                                             

                                            

                                               

  



  

   

                        

         

                                

             

  













     

      

   

     



    

     

 

  



      

       

 

    



  

                                                                                                                                         

        

                                                                                                                                         

                                                                                                                                         



                                                                                  

            



                                                                                                 

   



                                                                             



                                                                     

                        



 



  

                                                                                       

                         

           

                           

  



                                     

                         

                                                                                                                                                                                                                           

                                             

                                                                                                                                                                                     

 

                                                    



 

 

    

 



    

  

   

  



  



   

 

   

  

 

 

 



 

 



    



                                                              

                                           

                                                    

 

                                                                                                                                          

                                                                                 



  

         

                   

                                                         

       

        



  



     

   

      

                                              

                                             



  

   

 

                                                                                                                                                                               

  

                                                                                        

                                                 

       

                                                       

 

                                                                      

             



                                                       

                          

       

 



                                                                         

                                           

                        



                              

       

                     

                                              

 

                 

  

                                                                                                                                                                                                                 

                                                          

                                                                                  

             

                                               

    

                                                                    

                                                                                                     







         

       

                                

                      



                                                         

 

                                                                                                

      

                         

                                                              

  

  



    

                                    

                          

          

                                                                                 

                                    

                                         







                           

                   

               

      

             

           



               

                                                                                  

                              





   

                                                                                     

                               

      



                                                       





         

           

                                                                                                                          

                   

                                                                                                                       

                                                                        

                 





     

     

  



     

     







                                                                                    

                                                          



         

                  

  









  





 

  



    





  











 

                                                                                                                                               

 



                     

                           

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                         

                                                                   

  

                                                                                        



  



                                                                                     

                                                                                  

                                                                                   





 

                                              

  

                                                                                                                                                                          

   

                                                                                                                                                                        

                                                                                               



                                                                                                                             





                                                                                                           



                               

                                                                                                                                                                                                      

     

                 

   

  

  

  

   

  

  

 

 

  

   

 

   

 

   

 

                                                                      

                                                   

                                                             







 



                        

    



                                                                                                             

 



  

 

    



   

 

                                                                                                                                                 

                                                                                                                                     

     

      

    

     

  

                                                                                                                             

                                   

                                                                                                              

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                                                                                                                               

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

                                          



                        

 

                                                                                                                                                  

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                           

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                                                                                           

           



                             

                                                                                                                                                                                                                                     

                                                                                                                                                                                                          

                                                                               

                                                    

                                                 

                                                                                                                          

                                                               

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                                                                                                                                                                              



                                            

                                                                                                                                                                             

                            

                    

                                                                                                                                                           

                                                         





                                      

 





                                                        

 

                                                                                                                                                                      

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                                                                                                                     



                                                 

                                                            

  

                                             

                                                                           

                  

       

                                                     







                                                                                

                                                                                                                                      

           

  

                                                                                                                                  



                                                                                                            





                               

                         



                                                                                             

                                                                                                 





      

                                                

                                                                                                                      

                                                                                                                     

                                                                                                           

                                     

                                                          

    



                                                                                                          



                                         

                                                                                                                                                                           

                                                                                                                                                                                               

        

                                                                                                                            

                                                                                                                                                             

                                                                                                                                                                                                 

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                                     



                                                                                                                                                                                 

                                                                                                                                                                                                                                   

                                   

                                                                                                                                     

                                                                                                   

                                                                                

                                                                                                                                                                                                                    

                                                                                                                                                                                                                        

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                                            

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                                                                                                                                              

                                                                                                                                                                                                                                                     

                                                                                                                                                                          

                                               

  





    

  

  





    

       









             

                                                                                                                                  

                                                         

                                                                                                                                                                       

    



                                                                                                 

                        



                                                                                  

   

                                                                                                  



                                      

                                                                                                                                                                                                             

   

 



   

                                                                                                                                                                          

                         

                                                                                                          

                                                                                                                                     



                                                                                                                                                                             

    







            

                                                                                                                                                                           

                                                                                                                                                                       

             

 

                                                                                                                                 

                                                            

                

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    

                                                                                            

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                  



                                                                                                                           









                                                                                                                      

                                                                                               





                                                     

                                                                                                                                              

       

      

                                                                                                                                                                                                                                

                                                                                                                                                                                                                                             

                                                                                                                                                                                                                        

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               

                                                      

                                                             

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                                                                                                                            

                                                                                                                                                     

                                                                                                                  

  

         

      

 



   





  



      

  

      

    

  

 



  

  

 



                                                                       



                           

                                                                                                                                                             

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                                                                              





                                          

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    

                    

                                                                                                                                                   

                                                 





                                                                                     

                                           

                                                                                                                       



                                  



                                               





                                                                                                                                                               

                   



                                                            

                                                                                                                                                                                                                               

  





  





                                                   



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

 

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

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 

 

                                                                                               

                                                                                                                                              

                

                                                                                         



                                                        



                                                                                                                                  

                                                                                                                                          

                                                       

                                             

                                              

                         

                                                                                                                        

                                                                                                                                           

                                                                                                                                 



                                                                                                                                                    



                        

               

 



                                                               

                                                                            



      

          

                                                                  

                                            

                                                                                                                                                                                                                                                          

  

  

                               

                                          

            

                                                                                                           

                             

            



                             



                                                                                                                                 

                                                                                                                                                                                           

                                       

                                            

                          

                                        

 

                                                                                                                                       

  



            

                                                                                                                     

                                                                               

                    



                                                                                                                                                                                                                          



                               

                         

                                                                                                                                                                                                          

                                   

                                                                                                                                         





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                                                         



                                                                                                                   

                                                                                                                                                                              

 



                                                     

                                                                                        

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                                                                                                                                                                

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

                                         

                                                                                            



      

                         

 



        

                                                                 

                                                                                                                                                                    

                        

                                                                                        

                  

                                                                                                                                  

       



                                                                                                                        

 

                                                                                              



  

 



           

              

         

                                                                                                                                                         

                              

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                                      

                                                                      

                         

                                                                                               

                                                                 

   

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                                                                                                                                                                                                       

    

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  

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 

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

  

                                                                                                                                                                                               

             

 

      

         



    





 

    



                                                                                                                                                                                                    

                                                         

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                                                                   

                                                     

                                                                                                                                               

                                                                                                                    



                                 



                                                                                                  

                                                                                                                                                       

                                                                     

        



  

  

                                                                                                    

                                                                            

 

                                                                                                                  

  



       

                                                                           



     

                                                

                                                                                                 

                                                                                                                                                                                                                        

                                                                                                                                                                       

                                                         

                               

          

                                                                                  

      

                                                                     

                                                                                                  

              



                                                                     





                                                                                       

                            

                                                                       

                       

                         

                                                                                                                    

                             

            

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                                                                                                           

                                                 

                             

                                  

                                                      

                                                                 

                                                   

                         



              



 

  



 

  



 



 



 



 



  







 



  



 



   

                                                   



       

                       

                                                                                                                                 

                     

        

      



     

                           

                                                              

                                           

                            

                  

                            

  



                                         







                                              

                   

    



 



               

                                                          

                                                                                                          

   



    



     

 







   







 



     

     

 





   

    



  

             





  



 







  



     

  

   

 

     

       







 



 

 

 

  

  

       

   









  



  

  

 



 

                 

          

   





       

   

                                                                   

                                                            

                                                                



 

                                                                                                    



                       

             



           

                                                                                                                                                      



                                                                          

                                                                                                                  

                             



        

                                                                                                             

                                                                                                                                                                                            

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                                                                                                                                                    

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                                                                                                                                                                                                                     

                                         

                                                                                                 

          



     

                               

  



                                                                                                                                     

  

                                                                                                                       

                                                                       

                                                                                                                         





   

          



                                             



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                                                                   

                                                         



                                                                                

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



                                                                





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

                                                                                                                                        

                                                                

                                                                                                              

                 

                                                                           

  



         

                                                                                                                                                                            



  



   

                                                                                                  

                                                                                                                        





 







                                                                                   

  

 





                                                    





                                        







                                               

                                                        





                                                               







                                                   





       

                                                                                 





                                  



                                                                                         

                                                                                                     

         



                                                                            

                                                                     

                                                                          

 











  

 







 

 

 



 

   

  



  

   

   



 

 

  



  

 

 













 



   

   

 



 

  

 

  

  

  









 

 

 

 

  

    

  

 

 

  

 

 



 







 



  

    



 



 

  

 

 





 







 

 

 





 

 

 

 

   

  



 



 



 







 

 

 

 

 

 

 



 

 

  

 

 

 

 









  

 





                                                                                                                                     

                                                                                     



    

  



                                                                   

                                                                                              

                                



      

                                                                                   

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                                                                                                                                

  

            



                                                                                                           

        

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   

                      

                                            



                                                                                                        





                                                                                                  

          

  

   

  

  

                                      

                                                                                 

                                                        

                                         

                                                                                                                                                                                                                             



                

                                                                       

                                                                                                                                                

                                                                                                                                                                                                                                                     

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                                                                                          

                                                                                                     





                                       

                                                                                                                                                                                                                                                  

                                                                                                                                                                                                                                                             

                       

                                                                                                                                                                                                                                    

   

                                                                                                                                                                                                     

                      

 

                                                                                         

                                                                                              



                                                     

                                                                                                             

                         



                                                                                                                                             

                                                                                                        

                                                                                                                                                 

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                                                                                               

                                                                                                                                                                                                                                   

                                             

                                                                                                                                           

                         

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

                                       

                                 

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                               

                                

      



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                                                               

                                                                          

                                                                                                                                                                                                                                                                        

  





                                          

    



 

 

 

 



                                            

                                   

                                                              

                                                                                                                                                                                     



                                               

                                               

          



  

 



 

 

  

  





  

   





 

 

          

                                                                                                                                                                                                                        

       

                                                                                                                                                                                                                                                  

                                                                                                                                                                                                                       

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                                                                                                             



                                                                                                                                                

                                                                                                           

 

                                                                                    

                                                                                                                                                                                                                                                   



 



     





 

  

   



  

   

  

  











   





                                   

                              

               



                      







    

    

    

  

  

  

  

  

  

    

    

    

                                                    

                                    

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          

                                                                                                                                               

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     

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                                                                                                                                                         

                                                                                   

          

                                                                

                      

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                                                                                                                                                                                                                                                          

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                                     

                                                                                          

                                                                                           

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 

 

 

                                                                                                                           

                                                                                            

                                                                                                                                                                                                                                         

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  



                                                                                                                                   

                                                                       

                                                                                                                                              

 

                                                                                                                                                                                                                                                      

                                                            

                                                                     

                                                                                                                                                     

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                                                                                                                                                                                                                      



              

   





                       

 



   

   

     

     

                                                                                           

                                        

                                                                                                                                                    

                                                                                      

                                                          

                                                                                         

                              

                                                                           

                              

                                                                      

                                                                           



                                                                                                                  

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

                                                                                                                  

          

                                    

                        

                                                  

                                                                                  

                                                                           

                          

                             

           

                           

 

 

                                                     

                        



       

                                                                                                                                                 

                                                                                       

                                                                                                     



 



                                  

                                                  

                                                                                                                           

                                                                                                           

  



   

   

  

     

   

   

 

  

 

  

  



    

 

 

 



 

        



                                                                              

  

                          

    

                                                                                                                                                                                                                                         

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                                                                                                                                                                                  



                                                 

                                                                                                                                                                                                                                            

                                                                                                                                                                                            

                                                                                                                                                                                     

                                                                                                                                                       

                                                                       

                                   

                                                  

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                                                                                                                                            



                      

                                                                   

  





              



  

 

  





 

  

 

 



  

  

  

 



   

 



                                                

                                                                                                                                                                        

                                                                                                                                                                                      

                                             

                        

 

 







                               

               



                                                                  

 

 

   

   

  

   

 

 



                                                                                                                                    

  

   

 

    

                                                                                    

                             

                                                              

  

 





         

        

        

  

  

            

            



     



    

     

                                                                                                          

                                                                                                                                  

                                                                                                                                

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

                                                                                                                                                                                                                                                                           

                                                                                                 



  

                                                           

                

                                                                                                                                                                                                                                                                      





   

  

   

   

    

 

     

 





 

  







  







      

   



 



  















   

  

                                                       



              

        

                                                                                                                                    

                        

                                                                                                                                                                      

                        

                                             

  



            



     

                    



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                                                                        

                                                                              

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

                                                                                                                                                      

                                                                                                                                                                                                                           

                                                                                                                                                                                                                             

                                                                                                                                                                                                                                              

                   

                                                                                                                                   

                                                                                                                   

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                                                                                                                                    

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



                                                                    

                                                                                                                                                                                                                 

                                                                                                                                                                                                                               

               

                                                                                                                                   

                              

                                                                                                                                                                                                                     

                                                                                                                

                                                                                                                  

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                                      

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                                                                                           

                                   





    

    

    

    

     

     

 

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

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     

     

                                                              

                                                                  

                                              



                                                                                        

                    

                                    

                                                                                                                                               

                                                                                                     

                                                                                                                                                                                                                                                   

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                                                                                             

                        





                                                                                       

                          

 

                                                                                                                                                                                                            

                                                                                                                                                

                                                                                        

                                                                                                                 

                                                                              

       

                                                                                                                           

                                                                                 

                                                                                                                                                                                                                                         

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                                                                                                



                                                                                                       

                                                                                                                                 

                                                       

                                         

                                                                                                                                                        

                           

                                                                                                          

      



                                                        

                                                                         



                                                                                        

                                         

                                                                                          

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

             

                    

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                                                                                

                                                        





                                                                                          

  





               

     

     

     

     

                                                                             

              

                                                                                                   

  

 











  







 







 











 



 

                                                                                  

           

                     

                                           

                   

                                              







     

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                                                 

                                                

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                  

                                                                                                                                                                                                        

   

                                                                      

                                                                                                                                                                                  

                                                           

                                        

        



                                                   

  

                                                                                            

 





                  

                                   

                                                                                                                                      

                                                                                                        

  













  

  



  



  



 

 

 



 

 



 





 

 



  





 

 

 

 

 



 

 

 



  

  



   

 



 



 

  





 

 

 

 

 

 

 





  





  







 

 



   

 



 

 

 

       

 



                                                 

                                  









 

   

   

  



                   

                                                                                                                                                                                                                                                                                        

                                                                                                                                                        

                                                                                                                                                                           

                                                                                                                                                                                                



 

                                                                                 

    



                                                                                 

                                                                                       

                                                                                                                        

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                                                                                                                 

                                  

                         

        





 

                                           

           

                                                         

                                                    

                            

        

                                                        

                       

                                                           

         

   

       



                             

              

              





               

                 

                                               



  

 

                                                            



          



















             

     

           

           

                                                     

                                                                                                    

                                                                   

                                                         

           





  

                           

                             

  





                                                                                                       

  

 



   

                                 

                                                                                                                                                        

                                                                     

                                              

                             

                                                   

  



  



                                                                                                                            

                                                                                                                                                



               

                               

         

                                                         

    

                                               

                                   

      

    

                                                   

                         



                                           

                        

     

                                               

                                          

                                                                     

                                   

                                                    



 

   





 

 

  







  





 

 



 



 



 

       



                                                                                                                                               

                 

                                                                                                                 

                                                                                                                                         

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                                                                                             

                                                                                       

                                                                                                       

 



  

                                                                              











 





 

 

 

   



  



  

                            





                                       

                                                               

                   



   

                                                                                                                                                                        

                                                                                                                                                                                                                                                                               

                                                                                                                  

                                            

                                                     



                     

                                                                                                    





                                                                                          

       

      

                                                                                                                                                               

                                                                                        

                  

   

                             

                                                                                                   

                                                                                  

                                                                                                                                                                             

                                

                                                                                                                                                            

        

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                                

                                         

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 

                                                                                                                                                                                   

                                                                                                                  



                         

                    

                                                                             

                                                                     

             

                                                                                                                                               

                                                           

                  

 



                                                                                               

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              

 

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                                                                                                                                                                                                                      

                  

                                                                                                                                                                                                                  

                               



                                                                                                                                                                                                                              

  







 

  

             

                                                                

                                                             

              

   

   

                   



                

                                                                                                                                                    



                                                        

      



                                                                                                                               

                                                                                                                   

                                                                                                                                                                  

                      

                                                                             

                                                                                                                                                                                                                                                                    

                                                                                                                                                                                      

                                                   





        



  



                                                                                                      



                                                                      

             

                      

 

              

                                                                            

                     

                                                                                        

                                      

                                                                         

                         



                                                                                                               

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

                                                                                                                  

 

                                                                                                          

                                                                                                                        

    

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                                            



                    

                                   

                                                                                                                                                                              

                                                                                                                                                                                                                                                                  

 

 

     





 

                                                 

 

                                                            

                                                                                             

                 

                                                                                                                     



   



                                                                                                                             

                                                                                                                    

                                                                                                                                  

                                                                                                       

                                                                                                                                                                                                                                         

                                        

                                                                                                                                                                                          

                                                                                                                                                                                                                  



   

 

 





























 





 













 

 























































































                          







                              

                                                          

                                                                       

  



   

  

  

  

 









 

 

 

                                                                                              

                                                                                                

                                                                                        





 

  



  



  









                                                       

                                                      

                                                                                                                                           

  







 













     

       

  

  

   

   

   

   

   

                

   

 

    



 

   

   

 

 

         

    

    

                                                                                               

 

                                                                                               

                                                                                                                                                         

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

                                                                                                                                                                                                                                                                                       

                                                                                                                                                                                                                                                   

                                                                                                         

                                                                                                             

                                                                                                                                                                                                                                                         

                                                                                                                                                                                                                            

                                                                                     

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                                                                                                                                    

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                                                                                                                                                                                                                                       

                                                                                                                                                                                                              

                       

                                                                                                                                                                                                             

         

 

          



  



        

   

      



   





   

  



 

 

 

                                                                                              

                                                                                             

                                                                                                                                                                                                                         

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                                                                                                                                                                                                                                                          

                                                                                   

             

                                                                                                                 



                                                                                                              

                                                                                           

                                                 

                                                   

                                                 

                                                                                                                                  

  



                                                              

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                                                                                                                                                                                                                                                                

                                                                                                                                                                                                                                                 

                                                                                                                                                                                                                    

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                                                          

                                                                              

                                   

                                                                                  

                                                                                                                                         

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                                                                                                                              





                                                                                       

                                                                                                      

                                                                                                                                               

                                                                                                                                     

              

                                                                                                                                                                

                                                                                                                                                                                                                          

                                                                                                                                                                                



  

                                    

                                





      

                                                               

                                                                                                                                                 

           

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                                                                                                                                                                        

                                                                                  

                                                                          

                                                                                                                    

                                                    



                            

                                                                                             

    

                                                                                                                                                                

                                     

                                     

                                                         

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

                       

          



                                                                                                                             

 



                       







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

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

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

                                    

                                                                    



                                                     

                                                                                       

                

                                                                                                                                                                                                     



      

                          

 

                             

         

 

 

   

            

  



 

  



                                              

                                                  

                                        

           

       

      

 

                                                                                      

                

                  

                                                               

         

 



                                              

 





                                                                                                            

 

 

                                 

                                                            

                                                                                

                

                                                                                       

                                                                                       

                          

                                                                                                                                                                       

                                                 

                                                                                                                                                           



   

 





 

        

 



 

   

      

    

 

 

      

 



     

 



 

 



    



 

      



 



  

   





            

                  

                

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                                                                                                  

     

                                                           

                                                                                                                                                                                    

  









 

   



 

  



  

 

  

 







 

 

















                                                                                            



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                                                                                                                                                                                                     

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                                                                                                                                                                                                               

              

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                                                                                                                               

       

                                                                    

                                                                                           

     

    



                                                                                                                                                                                                       

                                                       



                               

   

                                                                                                           





               

  

                                                  

                                                                                                                         

 

                           

  



                 

                                                                                               

 

                                                                                                 

                                                                   

                                                 

    



                                 



           



         

                                                                                                                                                      

                                                                                                                



 

                                       

      

 



 

  







 



 









 











 



  







 





 

 



 

 













  





 

 

                                                                                     

       

                                                                                                                                   

                                                     



                                      



                       

                                           

 



                                                                                                       

             

                   

                                                             

 



                                                                              

                                                        

               

                                                                           

     

 

 

  

 



  

 





 

                                                                                                 

                                                             

                                         

                                                                                                          



             





                                                                                        

                                                    

  



                   



 





 

  









 















  





   



 



  









 





                               

                                                                                   

                                                            

                            

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                       

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    

                                                                            

                                

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                                                                                                  

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                                                                                 

                  

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  

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                                                    

                                     







                                  

                                                                                                         

                          

 

                           

                                                                                           

                          

             

                       

                     

                                                                                                                                    

  

























 

 





 

 





 





 

  







 







  

 







 







                                    

                    

                                                                                                

 

      

                                    



                

                                                                                                            

 

                                                                               

            

                                                                                                                                                  

 



                                                                                             

                                                                                                                                          

                                                                                                           

                                                                                                                                                                                                                                                                                        

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                                                                                                                                                                                                                                                                         

                              

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                                                                                                     

     

                                                                                                                                                                       

  

                                                                                                                                                                                                     

                                       

                                                                                                   

                    

                         

                                                                                                         



                





                                                                                                                                                                                                                                       

                                                   

                                                                                                                                                                                  

                                                          

                                                                                                                                     

                                                                                                                                                                                     

                    

                                                                          

                                                                                                                                                                                                   



   





    

 

   



 

   

 



 



                                                                                                                   

                                                                                                                               

              

                                                                                              

                                                                                  

                                                                             

                

                                            



      

                                                                                                                                 

                                                                          

  



                

                



 

   





   

    

  

  

   

    





   

    

                     

 

                                                                          



                                     

     

 

 

 

                                                                    

                                                                     

                                         

                      

                                            

 

     

                                          

             

            

                                  

                                                    

        

                                                                        

                 

  



                                  

                                                                         

                                                       





                                  

                                     

 

                                                                 

                                                                                                                                               



                  

                             

      

                                                                        

                                                      

                            

                          

 

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                                                                                                                

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                                                                   

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                                                                                                                                                  





                                                                              

                                                                                                                                                                                                                                                               

                                                                                                                                                                                                                                                

                                                                              

      





             

                                                                                                                                                             

                                                                                                                          

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                                                                                                                                                                                                                



                        

                                                  

      

                     

                                                          

                                                                                                                                                                         

                                                                                                 





                                     

                                                                                                          

                                                                                                                    



                                                                                                                                                     

 

             



             

                                                                                                                      





                                                      

                                                                     

                                                                         



                                                                                       

                                                                                                                                              





 

                                                            

                                      

                                                                                           

                      



                                    

                                                                                                                                                                                     

                                         

 



                                                             



                                                                           

                   

                                                                

          

                                                                                                                              

                                         





                                                                        

  

 

                                                                         

                                                                                                 

                            

        

                                                                            

               

                                                                                                                                                                         

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                                                                                                         



                  

                                                                                                                                                                                                                                        

                                                                                                                                                    

                          

                                                               



   







              

                                                                                                                

                                     

                                                                                                                                                                                 

                                                                                               

                                                                                                     



            



                                     

                                                                           

                            

                                  

                                                                                                           

  

 



            

                                                           

                                           

  

       

  

                                                                                   



   



   

      







 

   



                      

     

                                                                                                          

                                                                



                          

           



                                                                                                  

            



                                        

            

 

                                                 

      

                  

                                     

                                                                                



    

  

                                     

                                             



                                                                                                                                                                          

                                               

                              

        

                                                                       

 



          

                                                



  



                    

                                                 

                  

                                             





                                                                                              





                                         

                            

 



           

                         

                                                                                          

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                            

                                            

                                                                     



  











  





























 



























 

   

 

 





 

  

 









 

                                 

                                   

                                   







    







               



       







                                                                               

                   

       



                                                            



   

   



   

 

                 

                

    

                                    













   



                                             

                    





                           

 



                   

                                                                                  

                                    

                                  

               



                                                        

  

 

 

 









 



















 

   





  





















 

 











 

 













 

 



 

 

















 

 







 









                                                                                                                                    

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                                                                                                       

                                                                                                                                                                   

   

                                                        



 

              

                                           

                                                                 

                                                                

           



   





                  

                     

                                                                 

                



                          









                                                                                             

 

 

     

           

         

   

 

 



                  



                                                                           

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                                                                         

                                                                                                                                              

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   



        

                  

                                          



                

           



                                         





 

                         

 

                    

            

  

 

 



              

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                                                                                                                 

                         

                                                   

   

 

  

     

     

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          

                    

                                                 

        

             



                                                   

                                                    

   





 

        

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  

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                                                                                         

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                                                                                                   

                           



                     

                                                                    





                                                          

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