New Study Suggests Role for Hormone Therapy to Treat Even Small, T1a Breast Cancers

New Study Suggests Role for Hormone Therapy mone therapy was shown to generally be effective. to Treat Even Small, T1a Breast Cancers The risk of relapse from these very small tumors remains Patients with tumors under 0.5 cm have not been significant enough to lend weight to a recommendation of widely offered this treatment previously hormone therapy in addition to radiation, the authors note.

Many people diagnosed with breast cancers that are small treatment the patient was exposed to at the same time. but invasive could benefit from hormone treatment, a new “Those patients who may benefit from hormone therapy study led by physicians at Roswell Park Comprehensive should be given clear information about this possible course Center confirms. Their findings were published in the journal of treatment — and about its potential long-term toxicities,” JAMA Network Open. says Dr. Singh, who is senior author on the new publication.

Previously, patients with some small but potentially danger“The side effects of endocrine treatments can impact quality ous breast tumors — specifically, hormone receptor-positive, of life significantly, sometimes for several years, so they’re not human epidermal growth factor receptor (HER) 2-negative the right option for everyone.” breast cancer tumors measuring between 0.1 and 0.5 cm — were not included in studies on the efficacy of hormone therapy, says Leaders in Progressive Treatment Anurag Singh, MD, Professor of of Vascular Disease Oncology and Director of Radiation Research in the Department of Radiation Medicine at Roswell Park.

With nearly one in five women with breast cancer falling into this category of having a small but invasive breast tumor, they were previously underrepresented in research into the efficacy of hormone therapy, also known as endocrine therapy, with either tamoxifen or with an aromatase inhibitor.

The team, led by Dr. Singh, analyzed data on 42,708 patients from the National Cancer Database who were diagnosed with small, T1a breast tumors (larger The experts at the Vascular & Endovascular Center of Western New York provide minimally invasive surgical care and superb diagnostic testing than 0.1 cm, but no larger than utilizing state-of-the-art technology. 0.5 cm) between January 2010 and December 2015. The group • Five board-certified vascular surgeons included more than 31,500 • • Minimally Invasive Vein Care in both Buffalo and Niagara Falls Seamless care coordination with specialty providers patients who had received endo• Top 3% nationally-ranked vascular surgery practice crine therapy and another nearly 11,200 who had not. Affiliations with Catholic Health, Kalieda Health and Catholic Medical Partners

The team reports that among patients who had received hormone therapy, overall survival was better than in those who did www.vecwny.com not, and the addition of horHormone therapy also did not negatively impact any other