Decellularized Fish Skin Technology: Burns

Kerecis® GraftGuide™

What Types of Wounds Are Suitable?

■ Partial and full thickness wounds

■ Trauma wounds

■ Surgical wounds (donor sites, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence) 1-3

■ Burns

Thermal Burn

Contraindications

■ Contraindicated in patients with a known allergy or other sensitivity to fish 3-5

Scope of Usage

22 year old male, thermal burn to the back.

The patient with a past medical history of hydronephrosis presented with a 19% total body surface area thermal burn.

The mechanism of the burn was bonfire-induced, with clothing set alight.

The patient presented to the burn center two days post initial injury having had an initial treatment with silver sulfadiazine cream. A single application of fish skin graft resulted in good secondary intention healing for the patient, without the need for an autograft.

3a, 3b: Initial presentation images.

3c: Day 2 pre-treatment images.

3d, 3e: Day 2 – post dermabrasion and fish skin graft application.

3f: Post-operative day 4.

3g, 3h: Post-operative day 15.

3i: Post-operative day 21.

Scald Burn

Patient 3: 65 year old female, scald burn to the lower leg.

The patient had inflammatory arthritis and rheumatoid arthritis, chronic kidney disease stage 3, obesity and pulmonary valve dysfunction and concurrent small cell carcinoma stage IV and was undergoing chemotherapy.

The patient presented on day 10 post injury, with a 3% total body surface area scald burn, previous treatment was standard of care and Collagenase Santyl . Patient was discharged from the practice due to follow up limitations and chemotherapy treatments. During follow up (1 year after treatment), patient had improved pigment matching, skin was soft and pliable with no itching, and showed a full range of motion without limitation.

4a: Appearance of wound on day 10.

4b: Post debridement.

4c: Fish skin graft application.

4d: Post-operative day 8.

4e: Post-operative day 15.

4f: Post-operative day 25.