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The increased use of exogenous testosterone resulted in Congress publishing the Anabolic Steroid Act of 1990 which identified anabolic steroids as a drug class of their own and included them in the list of controlled substances.
2. What Is Testosterone And How Is It Produced? Testosterone is a steroid hormone that is found in both, men and women with higher levels in men, rather than women. It is a male sex hormone that is responsible for the development of male sex characteristics. Produced primarily in the testes, this steroid hormone is synthesized from cholesterol. The main source of testosterone in males and females is different as females most often depend on adrenal glands and peripheral tissue for testosterone synthesis whereas it is primarily synthesized by testes in men. The synthesis of testosterone, a steroid from the androstane group, depends on cholesterol and the activity of Leydig cells in the testes. Once synthesized, it is carried in the blood by sex-hormone-binding globulin (SHBG) and after it has been used, it is transported to the liver to be broken down into its inactive metabolites.
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