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GW 501516/Cardarine Basic information(3)
GW 501516/Cardarine Basic information(3)........................................................................................... 1 6.Health Benefits of Cardarine/GW501516................................................................. 2 7.Potential Risks/Side Effects........................................................................................ 6
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6.Health Benefits of Cardarine/GW501516
1) Cardarine Protects the Brain
In animals, GW 501516 protects brain vessels when they are under oxidative stress . Activation of PPARáş&#x; by GW 501516 could drive the development of nerve cells . Additionally, it prevents blood vessel dysfunction, especially in brain vessels .
2) Cardarine Benefits the Heart
Comparing with the others SARMS powders, GW 501516 prevents oxidative damage in the heart. It decreases the risk and severity of atherosclerosis (plaque buildup in the arteries) through a number of mechanisms. GW 501516 increased levels of nitric oxide, which protects against atherosclerosis.
It also reduces lesions and inflammation associated with atherosclerosis in mice. GW 501516 increases VEGF production from human blood vessel cells, which triggers cell and blood vessel formation .
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GW 501516 results in an increase of HDL cholesterol and a decrease in triglycerides in animal studies, potentially decreasing the risk of cardiovascular disease in patients.
3) Cardarine Increases Metabolism and Prevents Obesity
GW 501516 activates PPARáş&#x;, which may increase the breakdown of fatty acids and increase energy expenditure in muscle. This could help treat obesity.
PPARáş&#x; activates the expression of a number of genes involved in reducing cholesterol and increasing energy expenditure . This treatment could protect against weight gain due to diet.
Also, GW 501516 decreases glucose output by the liver and increases insulin sensitivity in mice. By driving muscle fiber development in mice, GW 501516 creates a resistance to obesity.
4) Cardarine Protects the Kidneys
In mice, it was shown to inhibit inflammation in kidney cells, and may protect against kidney disease. It does this by lowering MCP-1 expression that is generally increased in such kidney diseases .
5) Cardarine Helps the Immune System 3
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GW 501516 is associated with the suppression of inflammation . Activated PPARẟsuppresses inflammation in the liver in animals by inhibiting molecules that contribute to inflammatory responses.
GW 501516 can activate PPARẟ which protects specific skin cells from undergoing spontaneous cell death during the wound healing process . It was also shown to accelerate diabetic wound closure.
6) Cardarine Protects Against Liver Damage
PPARẟ activation by GW 501516 causes the liver to switch its energy source from glucose to fatty acids, thus reducing blood sugar.
In mice, GW 501516 inhibited IL-6, which may help prevent insulin resistance in liver cells . Short-term use can reverse the liver damage that was due to a high fructose diet.
Also, it can improve nonalcoholic liver disorder in mice.
7) Cardarine Improves Muscle Growth and Stamina
Activation of PPARẟ via GW501516 drives the development of muscle fibers in mice. These muscle fibers are associated with increased physical performance. 4
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They were able to run almost twice as long as other mice, indicating improved endurance.
8) Cardarine May Help Heal Skin Diseases
Activation of PPARẟ could improve the inflammation caused by psoriasis (a skin disorder).
9) Cardarine May Improve Blood Flow and Wound Healing
By activating PPARẟ, Cardarine may increase the synthesis of BH4, which increases nitric oxide production in blood vessels (eNOS).
Increasing nitric oxide helps improve blood flow. It also helps during wound healing.
10) Cardarine Has Antioxidant and Anti-inflammatory Potential
Not like other SARMS powder, Cardarine increases the production of the antioxidant enzymes SOD1 and catalase.
It also inhibits the production of inflammatory molecules such as MCP-1, TNF-alpha, IL-6, and NFκB . The anti-inflammatory effects can improve fibrosis caused by inflammation in rats. 5
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7.Potential Risks/Side Effects
GW 501516 increases cell death in liver cells and may cause fibrosis in mice with liver disease.
In animals, there is a potential risk to placental and fetal development with prolonged are large exposure to GW 501516.
In rats, GW 501516 can cause cancer. There are not enough studies done on humans to show the same effect.
GSK abandoned further development of the drug in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
Because GW 501516 has a vast amount of influence in a number of places in the body, you should consider its side effects before pursuing it as a treatment.
Then, how to use cardarine powder?
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