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Urolithin A
Product Description
Basic Characteristics Product Name CAS Number Molecular Formula Formula Weight
Urolithin A 1143-70-0
Synonyms
Urolithin A 8-Methyl Ether;
C13H8O4 228.2 2′,7-Dihydroxy-3,4-benzocoumarin 3,8-Dihydroxy Urolithin; 3-Hydroxy-8-methoxy-6H-dibenzo[b,d]pyran-6-one.
Appearance Storage and Handling
White crystalline powder Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Reference [1] Spendiff, S. et al. Mitochondrial DNA deletions in muscle satellite cells: implications for therapies. Hum. Mol. Genet. 22, 4739–4747 (2013) [2] Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 November 2009). “Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay”. 1
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J Agric Food Chem. 57 (21): 10181–6. doi:10.1021/jf9025794. PMID 19824638. [3] Milburn, M. V. & Lawton, K. A. Application of metabolomics to diagnosis of insulin resistance. Annu. Rev. Med. 64, 291–305 (2013). [4] Cerdá, Begoña; Tomás-Barberán, Francisco A.; Espín, Juan Carlos (2005). “Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability”. Journal of Agricultural and Food Chemistry. 53 (2): 227–235. doi:10.1021/jf049144d. PMID 15656654. [5] Laker, R. C. et al. Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat. Commun. 8, 548 (2017).
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