Whatis17-alphamethyltestosteronepowderusedforinfish?
Whatis17-alpha-MethyltestosteronePowder?
17a-Methyltestosterone(MT),asyntheticderivativeoftestosterone,isanandrogenic preparationgivenbytheoralrouteinacapsuleform.
Methyltestosteronealsoknownas17-alpha-Methyltestosterone,17a-MT,methyltestoras 17α-methylandrost-4-en-17β-ol-3-one,isasynthetic,orallyactiveandrogenic-anabolic steroid(AAS)and17α-methylatedderivativeoftestosteronethatisusedtotreatmaleswith androgendeficiency.
Inaquaticspecies,sexualdimorphismfrequentlyaffectsgrowthperformance.Forinstance, malegrowthissuperiorinNiletilapiaandgiganticfreshwaterprawn,whilefemalegrowthis fasterinThaiclimbingperchandcommonsilverbarb,etc.Togetherwithpossiblegrowth
benefits,monosexstockscanbemorebeneficialtoaquaculturebecausetheyreduce unintendedreproduction,minimizeaggressiveinteractions,andincreaseharvestsurvival rates.Inparticular,Niletilapiacultureshowedinearlierstudiesthatmalemono-sexculture producedmuchmorefishthanmixed-sexculture.
Niletilapiahasrecentlybecometheworld'sfirsteconomicallysignificantfreshwaterfish.In Thailand,ithasthehighestyieldofanycultivatedfreshwaterspecies,withanestimated 200,000tonsproducedeachyear.Theaquaculturesectorreliesheavilyontheproductionof all-maletilapiafry.All-maleproductiontechniquesincludedhandlingselection,hormone injection,pulse-electricfieldinduction,inter-specifichybridization,heattreatment,creating YY-supermale,andothergenetictechnology.Eachtechniquehadadvantagesand disadvantages.Howeverinfishfarming,syntheticsteroidalhormonesarefrequently (commercially)administeredbyoraland/orimmersiontreatments.Themostefficientand leastexpensivemethodissexreversalwiththeuseof17α-methyltestosteronepowder.
Thesyntheticsteroid17-alphamethyltestosterone(17MT)powderhaslongbeenusedasa feedingredientincommercialfarmstogenerateall-maletilapiafish.For21-28days,thefry ofearlylifestages(14dayspost-hatch)arefedthe17MT-treatedfeed.Aquaculturistshave
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Conclusion
Thecurrentstudyshowedthatwhen17-methyltestosteronepowderwasappliedthrough immersiontreatmentsataconcentrationof1000g/Lfor6honceaweek,itwaspossibleto obtainhighratesofmasculinizationinredtilapia.Foroperators,thisprotocolismore practical,cost-effective,andsecure.So,themasculinizationtechniquesusedincommercial redtilapiafarmsweredirectlyderivedfromtheimmersionapproachthatwasevaluated.
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