Lymphocyte Activation Gene - 3 Protein Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK, AND OPPORTUNITY ANALYSIS, 2018-2026
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REPORT DESCRIPTION Lymphocyte Activation Gene - 3 Protein Market – Overview Immune checkpoint receptors such as lymphocyte activation gene - 3 (LAG-3) protein are found on cell surface of effector T cells and regulatory T cells (Tregs). T cells are a type of white blood cells that eliminate unhealthy or foreign cells that enter the immune system. Function of lymphocyte activation gene - 3 protein is to control T cell response, activation, and growth. Lymphocyte activation gene - 3 turns off the immune response when a T cell is activated to eliminate a target cell. This prevents the T cells from harming healthy cells. Moreover, lymphocyte activation gene - 3 protein is associated with T cell exhaustion in which the T cells become desensitized and lose their ability to function. LAG-3 is closely associated with regulation of cytotoxic T cells and regulatory T cells, which has attracted attention of researchers and manufacturers as a therapeutic target against cancer. In cancers, lymphocyte activation gene - 3 expressing exhausted cytotoxic t cells and regulatory T cells (Tregs) are found to be gathered at tumor locations. Recent studies reported that inhibiting LAG-3 functions allows T cells to regain their cytotoxic function and affect tumor growth. There are several LAG-3 protein antibodies in the clinical trials, which are expected to further advance in clinical trials over the forecast period.
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REPORT DESCRIPTION Lymphocyte Activation Gene - 3 Protein Market Taxonomy: By Drug Type: ●
BMS-986016 (Relatlimab)
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IMP321
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IMP701
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MGD013
By Cancer Type: ●
Breast Cancer
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Melanoma
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Solid Tumors
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REPORT DESCRIPTION Lymphocyte Activation Gene - 3 Protein Market: Key Players ●
Bristol-Myers Squibb.
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Icell Kealex Therapeutics.
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Incyte Corporation.
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MacroGenics, Inc.
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GlaxoSmithKline Plc.
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Crescendo Biologics Ltd.
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Regeneron Pharmaceuticals Inc.
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Sutro Biopharma Inc.
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