Pharmacology for Canadian Health Care Practice 3rd Edition Lilley Test Bank
Chapter 54: Biological Response–Modifying Drugs Lilley: Pharmacology for Canadian Health Care Practice, 3rd Canadian Edition MULTIPLE CHOICE 1. A patient is receiving interferon therapy. What expected adverse effect should the nurse tell
this patient about? a. Anemia b. Increased appetite c. Constipation d. Flulike effects ANS: D
Patients who receive interferon therapy may experience flulike effects, fatigue, anorexia, dizziness, nausea, vomiting, and diarrhea. Patients on interferon therapy will not experience anemia, increased appetite, or constipation. DIF: Cognitive Level: Comprehension
REF: p. 1010
2. Lymphokine-activated killer (LAK) cells, which multiply as a result of interleukin therapy, do
what? a. They directly inhibit deoxyribonucleic acid (DNA) and protein synthesis. b. They destroy cancer cells and ignore normal cells. c. They destroy cancer cells by destroying all types of cells. d. They prevent virus replication and prevent viruses from penetrating healthy cells. ANS: B
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LAK cells recognize cancer cells, ignore normal cells, and destroy the cancer cells on contact, thus avoiding the toxic effects of antineoplastic drugs. DIF: Cognitive Level: Knowledge
REF: p. 1014
3. Capillary leak syndrome during interleukin therapy may result in which problem? a. Renal failure b. Asthma c. Ecchymosis d. Heart failure ANS: D
When capillary leak syndrome occurs, the capillaries lose their ability to retain vital colloids, and these substances migrate into the surrounding tissues, resulting in massive fluid retention. As a result, heart failure, myocardial infarction, and dysrhythmias may occur. DIF: Cognitive Level: Comprehension
REF: p. 1016
4. Which is an effect of colony-stimulating factors (CSFs)? a. Multiplication of T cells b. Decreased neutrophil counts c. Increased cytotoxic activity of natural killer (NK) cells d. Stimulation of certain immune cells
