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Celebrating C l b ti 15 Years Y October 2014

Adding Life to Years at the New Jersey Institute for Successful Aging New Department of Geriatrics & Gerontology Do I really need to get a flu vaccine?

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12TAB COURIER-POST, Thursday, October 16, 2014

The University Doctors MedicaLink

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Hammonton 609.704.0185 Mount Laurel 856.380.2400 Sewell 856.218.0300 Stratford 856.566.7020 www.theuniversitydoctors.com

Kennedy University Hospital is the principal hospital of the Rowan University School of Osteopathic Medicine. Other affiliated hospitals and health systems include Lourdes Health System, Inspira Health Network, Cooper University Hospital, Meridian Health System, Christ Hospital and Atlantic Health System.

COURIER-POST, Thursday, October 16, 2014 11TAB

That may not be a cold, could be fall allergies

Ragweed, mold most common allergens this time of year, experts say

By SERENA GORDON HealthDay

Many parents complain that as soon as school starts, their child inevitably catches a cold. But, while kids do swap their fair share of germs during the school day, not every runny nose stems from a cold — often, those sneezy symptoms are the result of fall allergies. “When school starts, most parents think a runny nose has to be a cold, but a lot of times it’s really hay fever caused by ragweed,� said Dr. Joseph Leija, an allergist at Loyola University Health System’s Gottlieb Memorial Hospital in Chicago. Leija also conducts the official pollen counts for the Midwest.

In most areas of the country, ragweed is the most common fall allergen. And ragweed often causes suffering until the first hard frost occurs, according to Dr. Blanka Kaplan, an allergist and immunologist with the North Shore-LIJ Health System in Great Neck, N.Y. Why is ragweed such a problem? Well, just one plant can produce up to one billion pollen grains. And those grains are very light and travel easily. Depending on where you live, symptoms may start in early August and they can last through October, according to the American Academy of Allergy, Asthma and Immunology (AAAAI). Warmer temperatures and rising levels of carbon dioxide in the atmosphere may be extending the ragweed growing season, the AAAAI reports.

Symptoms of fall allergies are similar to those seen in the spring and may include sneezing, a runny nose, itchy or watery eyes, headache, sinus pain and pressure, and increased asthma symptoms, Leija said. The AAAAI noted that ragweed allergies can sometimes cause hives on the skin.

Leija said that, ideally, people with allergies should start taking their allergy medicines before symptoms begin. “If you wait until symptoms develop, it can take days for the CP-0010538596

0RUH LQIRUPDWLRQ 7R OHDUQ PRUH YLVLW WKH $PHULFDQ $FDGHP\ RI $OOHUJ\ $VWKPD ,PPXQRORJ\ DW ZZZ DDDDL RUJ medications to start to work,� he said.

Kaplan said over-the-counter antihistamines, such as Allegra, Claritin and Zyrtec, are usually good at controlling allergy symptoms. Some people also benefit from the addition of a steroid nasal spray that helps shrink swollen nasal tissue, she said. “If you try over-the-counter medications and they don’t help, talk to your doctor, there are various options available,� said Kaplan, noting that your primary-care doctor may refer you to an allergist to find out exactly what you’re allergic to.

If medications don’t give you relief, both experts said that allergy shots (immunotherapy) may be an option. Standard immunotherapy takes several months before it’s effective, however. Leija said a newer type of immunotherapy called rush therapy involves getting five to 10 injections in a single day.

With this type of therapy, you may get full immunity within two weeks, according to Leija.

But, he added, not all insurance companies cover this therapy.

Both Leija and Kaplan recommend keeping windows closed, and filtering your indoor air with an air conditioner. (Be sure to keep the air conditioner filter clean.) Kaplan said it’s a good idea to stay indoors if you can when the pollen counts are high. Leija suggested taking a shower when you come into your home, or before bed, to get the pollen out of your hair and off your skin.

And, both experts recommended taking allergy and asthma medications on a regular schedule.

If mold is an issue for you, Leija said to check your yard for any standing water because it will encourage mold growth. The same goes for decaying leaves in your yard or gutters. If possible, hire someone to remove the leaves for you. If you have to do it yourself, wear a mask while you’re working. If you have mold inside your home, he said that a solution of bleach and water can kill mold spores.

10TAB COURIER-POST, Thursday, October 16, 2014

Experts offer ‘Lucky 13’ tips for safe and healthy Halloween

From decorative contact lenses to face paint, experts warn that Halloween costumes may result in a wide array of potentially serious health issues from falls to allergic reactions.

From decorative contact lenses to face paint, experts warn that Halloween costumes may result in a wide array of potentially serious health issues from falls to allergic reactions.

The U.S. Food and Drug Administration along with the U.S. Centers for Disease Control and Prevention and the U.S. Consumer Product Safety Commission provided the following “lucky 13” guidelines on how kids and their parents can enjoy a fun and safe Halloween: • Choose flame-resistant costumes.

Store-bought costumes should read “flame-resistant” on the label.

Homemade costumes should be made out of flame-resistant fabrics, like polyester or nylon.

• Glow in the dark. Wear bright colors or costumes with reflectors to ensure being visible in the dark. Also, to avoid tripping, make sure costumes aren’t too long.

• Avoid masks. Masks can make it more difficult to see properly.

Replace them with makeup and hats.

• Test makeup. Put a small amount of costume makeup on one arm about two days before dressing up. Do not use the makeup if it triggers an allergic reaction, which may include a rash, swelling or other sign of irritation.

• Check makeup ingredients. Avoid using any makeup containing additives that are not FDA-approved.

• Be cautious about decorative contact lenses. Avoid wearing any costume lenses unless you have seen an eye-care professional and been properly fitted and instructed on their use.

Halloween safety measures apply to more than just costumes, the experts

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0RUH LQIRUPDWLRQ 7KH $PHULFDQ $FDGHP\ RI 3HGLDWULFV DOVR RIIHUV +DOORZHHQ VDIHW\ WLSV noted. When trick-or-treating, kids and parents should keep the following tips on candy in mind: • Candy should not be eaten until it has been inspected at home.

• Trick-or-treaters should fill up on a healthy meal or snack before they start knocking on doors so they won’t be tempted to eat candy before it has been checked.

• Don’t let kids accept or eat any candy or food items that are not in unopened store wrappers.

• Very young children should not receive or be allowed to keep any choking hazards, such as gum, peanuts, hard candies or small toys.

• Inspect all candy to make sure no one has tampered with it. Some signs to look for include discoloration, pinholes and small tears in wrappers.

Toss anything that looks suspicious.

Anyone attending a Halloween party or event, the experts add, should also consider taking the following precautions: • Avoid drinking any juice than hasn’t been pasteurized, such as packaged juice products that may have been made on site. Typically, the juice found in grocery stores in the freezer or refrigerator sections is pasteurized as well as any beverages on the shelf in boxes, bottles or cans.

• Before bobbing for apples, wash the produce thoroughly to reduce exposure to dirt and bacteria.

Source: HealthDay

COURIER-POST, Thursday, October 16, 2014 9TAB

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By DENNIS THOMPSON HealthDay Overall adult diabetes rates appear to have leveled off during the past four years in the United States, in stark contrast to the two decades prior, which saw a doubling of the chronic disease, according to a new federal study.

The total number of people living with diabetes increased an average 0.6 percent annually between 2008 and 2012 while the number of new cases actually fell an average 5.4 percent, researchers for the U.S. Centers for Disease Control and Prevention (CDC) reported. That compared with an average 4.5 percent annual increase between 1990 and 2008, they said.

Not all groups in the United States have benefited, however. Diabetes rates continue to rise for blacks, Hispanics, the aging and the poorly educated, according to the report published in the Sept. 24 Journal of the American Medical Association. “We are beginning to see a slowing of the increase in diabetes, and potentially a plateauing,� said study co-author Ann Albright, director of the CDC’s Division of Diabetes Translation. “It should give us all some optimism, but it does mean we should not sit on our laurels.�

Success in tackling the United States’ diabetes epidemic likely plays a large role in the leveling off of rates, Albright said. “Obesity, of course, is a major risk factor for type 2 diabetes, which is the predominant form of the disease,� she added.

The researchers noted that the growth of diabetes and obesity rates have both slowed as declines have taken place in people’s overall calorie intake and food purchases.

For the study, CDC researchers analyzed data for nearly 665,000 adults between 20 and 79 years old. The data was taken from the National Health Interview Survey, an annual survey used to monitor illness and track progress toward health goals in the United States.

In a 20-year period, they found the total number of diabetes cases doubled from 35 per 1,000 people in 1990 to 79 per 1,000 in

0RUH LQIRUPDWLRQ 7KH &'& KDV PRUH RQ WKH 1DWLRQDO 'LDEHWHV 3UHYHQWLRQ 3URJUDP DW ZZZ FGF JRY GLDEHWHV SUHYHQWLRQ 2008. The annual number of new diabetes cases more than doubled in that time frame: from 3.2 per 1,000 people in 1990 to 8.8 per 1,000 in 2008.

But something changed between 2008 and 2012.

The total number of diabetes cases increased only slightly, to 83 per 1,000 people in 2012, while the number of new cases declined annually, to 7.1 per 1,000 in 2012.

The fact that the total number of people with diabetes has risen slightly is not necessarily a bad thing, said Dr. Robert Ratner, chief scientific and medical officer for the American Diabetes Association.

It shows that “we’ve had an impact on death rates,� he explained. “People with diabetes are living longer and living healthier.�

Albright added that the decrease in new cases is a very positive development. “Hopefully, we will begin seeing fewer people with diabetes because we are seeing fewer new cases of diabetes,� she said. “But even with the slowing, we’re still going to have lots of people with diabetes. This is telling us that some of the things we’ve been doing have been helping the situation, but we are going to have to monitor this carefully — and we can’t get lax because we have a long way to go.�

The CDC, in particular, has made inroads with its National Diabetes Prevention Program, an evidence-based lifestyle change program that can cut a person’s risk of type 2 diabetes in half through diet and exercise.

However, the continued increase in diabetes rates among blacks, Hispanics and people without a high school education reflects the difficulty in making these sorts of programs available to people at a lower social or economic level, Albright said. “You have to begin to look at things like poverty level, access to these kinds of diabetes

prevention services, making sure that these services are culturally appropriate and easy for people to access,� she said.

And even with the plateau observed by the CDC, diabetes will remain a costly public health crisis for years to come, Ratner noted.

“Keep in mind, in 2012, we spend $245 billion on diabetes and its complications,� he said. “Unless we do something to really stop the development of diabetes, we’re going to end up spending even more money, and diabetes is going to bankrupt us.�

8TAB COURIER-POST, Thursday, October 16, 2014

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By RANDY DOTINGA HealthDay While a burly kid on the playground may be the stereotype of a childhood bully, a new study suggests some of the most damaging bullies are as close to home as you can get: they’re siblings who tease, make fun of and physically hurt their brothers and sisters.

Youngsters who were bullied by siblings were more than twice as likely to report depression or self-harm at age 18 as those who weren’t bullied by siblings. They were also nearly twice as likely to report anxiety as they entered adulthood, according to new research.

Although the study only found an association and doesn’t prove that these factors resulted directly from sibling bullying, “we believe it very likely that interventions to reduce sibling bullying would improve children’s mental health in the longer term,� said study lead author Lucy Bowes, a postdoctoral research fellow at the University of Oxford.

Bullying has received tremendous attention in the United States in recent years. But there’s been much less research into bullying among siblings.

In the new study, Bowes and colleagues examined the results of studies of just over 2,000 people in the United Kingdom who were surveyed via questionnaire in 2003 and 2004 at an average age of 12, and then answered a survey again at the age of 18.

The researchers defined bullying as “acts such as name-calling, being made fun of, as well as more physical acts of violence, like being hit or kicked,� Bowes said. The kids who experienced the most bullying were most likely to report problems at the age of 18.

The study design didn’t allow the researchers to pinpoint the exact level of extra risk that the most-bullied CP-0010538593

kids faced of being depressed, anxious or hurting themselves.

However, “just over 10 percent of our sample reported being bullied several times a week, and in this group there was a significant risk of psychiatric ill-health,� Bowes said.

The research didn’t compare the effects of sibling bullying to other kinds of bullying, but the study pointed out that there’s “little opportunity for victims to escape� from bullies when the tormentor is a sibling.

Bowes said it’s not clear whether the bullying actually caused the later mental problems or if something else — perhaps being sensitive and vulnerable — could have contributed to both bullying and the mental problems. The study also didn’t look

at whether any of the victims were also bullies themselves and whether that factor could have affected their later mental health.

Parents should keep an eye on sibling rivalry, advised Rachel Annunziato, an assistant professor of clinical psychology at Fordham University in New York City, who reviewed the study’s findings. “Then it’s important to assess how often it is occurring and how our children react to it,� she said. “These are conversations that we should consider having with our children individually but also as families.�

Study lead author Bowes had advice, too. “We know very little about what might help stop the bullying. However, in my own

research on school bullying, we’ve found that parents can support their children by listening to them, and providing warmth and support,� she said. “This can help both victims and bullies alike.�

The study was released online in September advance of publication in the October print issue of Pediatrics.

A second study, in the same issue of the journal, suggests that if children start having problems at night with nightmares, night terrors or sleepwalking, parents might want to talk with that child about bullying.

That’s because the study of almost 7,000 children found a significantly increased risk of nightmares, night terrors or sleepwalking — collectively known as parasomnias — in children who were being bullied.

0RUH LQIRUPDWLRQ )RU PRUH DERXW EXOO\LQJ JR WR VWRSEXOO\LQJ JRY The odds of any parasomnia in an 8-year-old child who was the victim of a bully were increased by 42 percent compared to children of the same age who weren’t affected by bullying. At the age of 10, the odds of having any parasomnia jumped by 75 percent for children affected by bullying, the investigators found.

Nightmares were the most common parasomnia for children who had been bullied, according to the study authors, Dieter Wolke and Suzet Tanya Lereya, of the University of Warwick in England.

6TAB COURIER-POST, Thursday, October 16, 2014

COURIER-POST, Thursday, October 16, 2014 7TAB

The University Doctors MedicaLink

Adding Life to Years at the New Jersey Institute for Successful Aging

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To schedule an appointment, call 856.566.6843 ąĂƫ /0ƫ 1.!(ƫ + Čƫ 1%0!ƫāĉĀĀƫđƫ 0. 0"+. Čƫ ƫĀĉĀĉą rowan.edu/som/njisa

The University Doctors MedicaLink is an Advertorial Supplement published by Rowan University School of Osteopathic Medicine (RowanSOM). RowanSOM staff: Mary Louise Bianco-Smith (editor), Julia Swope, Gerald Carey, Lynne Yarnell, Lucy McGorry, Bernardine Jones. Please send inquiries via email to: sominfo@rowan.edu or RowanSOM Marketing Department, University Doctors Pavilion, Suite 1300, 42 East Laurel Road, Stratford, NJ 08084, 856.566.6191.

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The University Doctors MedicaLink

Adding Life to Years at the New Jersey Institute for Successful Aging

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We Understand ƫ ƫ Available clinical services: đƫ !)+.5ƫ //!//)!*0ƫ .+#. ) đƫ +),.!$!*/%2!ƫ !.% 0.% ƫ //!//)!*0ƫ .+#. ) đƫ 1*0%*#0+*Ě/ƫ %/! /!ƫ )%(5ƫ !.2% !ƫ !*0!. đƫ !$ 2%+. (ƫ ! (0$ƫ !.2% !/ đƫ !1.+,/5 $+(+#% (ƫ !/0%*# đƫ +1/!ƫ ((/ƫ .+#. ) đƫ +/,%0 (ƫ !.% 0.% ƫ +*/1(0 0%+*ƫ !.2% ! !ƫ (/+ƫ,.+2% !ƫ$! (0$ƫ/!.2% !/ƫ%*ƫ 1./%*#ƫ +)!/ƫ * ƫ //%/0!

%2%*#ƫ %(%0%!/ċƫMedicare and most insurances accepted.

U.S. News & World Report has recognized Rowan University School of Osteopathic Medicine as one of the nation’s top 20 schools for Geriatric Medical Education for thirteen years.

To schedule an appointment, call 856.566.6843 ąĂƫ /0ƫ 1.!(ƫ + Čƫ 1%0!ƫāĉĀĀƫđƫ 0. 0"+. Čƫ ƫĀĉĀĉą rowan.edu/som/njisa

The University Doctors MedicaLink is an Advertorial Supplement published by Rowan University School of Osteopathic Medicine (RowanSOM). RowanSOM staff: Mary Louise Bianco-Smith (editor), Julia Swope, Gerald Carey, Lynne Yarnell, Lucy McGorry, Bernardine Jones. Please send inquiries via email to: sominfo@rowan.edu or RowanSOM Marketing Department, University Doctors Pavilion, Suite 1300, 42 East Laurel Road, Stratford, NJ 08084, 856.566.6191.

COURIER-POST, Thursday, October 16, 2014 5TAB

The University Doctors MedicaLink Information Resour

Ask The University Doctors

Do I really need to get a flu vaccine?

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WKHLU RZQ KHDOWK %HFDXVH XQYDFFLQDWHG SHRSOH DUH FRQWDJLRXV EHIRUH WKH\ H[SHULHQFH ÀX V\PSWRPV WKH\ ULVN LQIHFWLQJ QHZERUQ LQIDQWV DQG RWKHUV ZKR KDYH PHGLFDO FRQGLWLRQV WKDW PDNH WKHP SURQH WR FRPSOLFDWLRQV IURP WKH ÀX )OX YDFFLQHV DUH VDIH DQG FDQQRW FDXVH WKH ÀX EHFDXVH WKH\ DUH PDGH IURP GHDG RU YHU\ ZHDNHQHG YLUXVHV 7KH YDFFLQH LV DYDLODEOH DV D VWDQGDUG LQMHFWLRQ D PLFURĥQHHGOH WKDW LQMHFWV WKH YDFFLQH LQWR WKH VNLQ UDWKHU WKDQ WKH PXVFOH DQG DV D QDVDO VSUD\ 6R UROO XS \RXU VOHHYH DQG JLYH \RXU KHDOWK DQG WKH KHDOWK RI WKRVH DURXQG \RX D UHDO VKRW LQ WKH DUP WKLV PRQWK Dr. Charlene Chick is a family physician and a member of the faculty at the Rowan University School of Osteopathic Medicine.

To schedule an appointment with Dr. Chick, please call 856.566.7020. The office is located at 42 East Laurel Road, Suite 2100, Stratford, NJ 08084.

4TAB COURIER-POST, Thursday, October 16, 2014

The University Doctors MedicaLink

HEALTH LECTURES

All lectures will be held at the Camden County Library – Voorhees Branch, 203 Laurel Road, Voorhees, NJ 08043.

Please call 856.566.6207 or email sominfo@rowan.edu to register.

Move to Get F.I.T. (Frequency, Intensity, Time) 0$.5*ĆŤ ( .ÄŒĆŤ ÄŒĆŤ ÄŒĆŤ 1 0%+*ĆŤ ++. %* 0+.ÄŒĆŤ !3ĆŤ !./!5ĆŤ */0%010!ĆŤ"+.ĆŤ 1 !//"1(ĆŤ #%*#ƍĨ ÄŠ Monday, November 3, 11 am to 12 pm Conference Room C Alzheimer’s and Related Disorders in the Elderly .Ä‹ĆŤ +* ( ĆŤ +((ÄŒĆŤ .+"!//+.ÄŒĆŤ !, .0)!*0ĆŤĆŤĆŤ +"ĆŤ !.% 0.% /ĆŤ * ĆŤ !.+*0+(+#5ÄŒĆŤ

Tuesday, November 4, 11 am to 12 pm +*"!.!* !ĆŤ ++)ĆŤ Caregiving for Patients with Dementia .Ä‹ĆŤ .!3ĆŤ 5#.!*ÄŒĆŤ !.% 0.% ĆŤ /5 $% 0.5ĆŤ !((+3ÄŒĆŤ !, .0)!*0ĆŤ+"ĆŤ !.% 0.% /ĆŤ * ĆŤ !.+*0+(+#5ÄŒĆŤ

Friday, November 14, 10:15 to 11:15 am +*"!.!* !ĆŤ ++)ĆŤ What’s New in Diabetes Management .Ä‹ĆŤ (%6 !0$ĆŤ !("!.ÄŒĆŤ (%*% (ĆŤ //%/0 *0ĆŤ .+"!//+.ÄŒĆŤ ! % %*! *ĆŤ * + .%*+(+#%/0ĆŤ3%0$ $!ĆŤ *%2!./%05ĆŤ + 0+./ Thursday, November 20, 11 am to 12 pm Conference Room C

SPEAKERS BUREAU The University Doctors can partner with you at your event or meeting to educate our community on almost any medical or health care related subject. Please call 856.566.6207, or email sominfo@rowan.edu to arrange for a speaker at least three weeks before your event or meeting.

The SOLSTICE clinical study is evaluating the safety and effectiveness of an investigational drug for moderate to severe endometriosis pain symptoms.

The study may last up to approximately 20 months and involve about 14 study visits.

You may be able to join the study if you: Ä‘ĆŤ .!ĆŤÄ Ä‰ĆŤ0+ĆŤÄ…ÄŠĆŤ5! ./ĆŤ+( ĆŤ * ĆŤ$ 2!ĆŤ*+0ĆŤ#+*!ĆŤ0$.+1#$ĆŤ)!*+, 1/! Ä‘ĆŤ 2!ĆŤ !!*ĆŤ/1.#% ((5ĆŤ % #*+/! ĆŤ3%0$ĆŤ!* +)!0.%+/%/ĆŤ%*ĆŤ0$!ĆŤ, /0ĆŤÄ Ä€ĆŤ5! ./ĆŤĆŤ and have pain symptoms during your period and at other times in your menstrual cycle Ä‘ĆŤ .!ĆŤ*+0ĆŤ0 '%*#ĆŤ, %*ĆŤ)! % 0%+*ĆŤ0+ĆŤ0.! 0ĆŤ ĆŤ $.+*% ĆŤ %/! /!ĆŤ+0$!.ĆŤ0$ *ĆŤĆŤ ĆŤ endometriosis Ä‘ĆŤ +ĆŤ*+0ĆŤ$ 2!ĆŤ ĆŤ$%/0+.5ĆŤ+"ĆŤ+/0!+,+.+/%/ĆŤ+.ĆŤ+0$!.ĆŤ +*!ĆŤ %/! /! Ä‘ĆŤ .!ĆŤ*+0ĆŤ,.!#* *0ĆŤ+.ĆŤ .! /0"!! %*#ĆŤ+.ĆŤ,( **%*#ĆŤ0+ĆŤ#!0ĆŤ,.!#* *0ĆŤ3%0$%*ĆŤĆŤĆŤ the next 24 months $!.!ĆŤ .!ĆŤ+0$!.ĆŤ.!-1%.!)!*0/ĆŤ0+ĆŤ !ĆŤ%*ĆŤ0$!ĆŤ/01 5ĆŤ0$ 0ĆŤ0$!ĆŤ/01 5ĆŤ + 0+.ĆŤ3%((ĆŤ %/ 1//ĆŤ3%0$ĆŤ5+1ĆŤ0+ĆŤ !0!.)%*!ĆŤ%"ĆŤ5+1ĆŤ .!ĆŤ!(%#% (!ĆŤ0+ĆŤ, .0% %, 0!Ä‹ 01 5ĆŤ, .0% %, 0%+*ĆŤ%/ĆŤ2+(1*0 .5Ä‹ĆŤ +1ĆŤ3%((ĆŤ.! !%2!ĆŤ ((ĆŤ%*2!/0%# 0%+* (ĆŤ/01 5ĆŤ medications and study-related tests and procedure at no cost.

To learn more or see if you may qualify for the study, visit www.TheSolsticeStudy.com, Text ENDO1 to 87888 or call Rowan University Clinical Trials office at 856-566-6474.

COURIER-POST, Thursday, October 16, 2014 3TAB

The University Doctors MedicaLink

New Department of Geriatrics & Gerontology at RowanSOM 5RZDQ 8QLYHUVLW\ 6FKRRO RI :RUOG 5HSRUW DV RQH RI $PHULFD¶V EHVW VFKRROV IRU JHULDWULF PHGLFDO 2VWHRSDWKLF 0HGLFLQH KDV EHFRPH MXVW HGXFDWLRQ WKH WK PHGLFDO VFKRRO LQ WKH 8QLWHG 'HVSLWH WKRVH DFKLHYHPHQWV 6WDWHV Ħ DQG WKH ¿UVW LQ 1HZ -HUVH\ Ħ 'U &KRSUD VD\V ³, VWLOO JHW WKH WR HVWDEOLVK D GLVWLQFW GHSDUWPHQW RI IHHOLQJ RXU ZRUN KDV MXVW EHJXQ ´ *HULDWULFV *HURQWRORJ\ $W DQ 6KH PD\ EH ULJKW :LWK WKH HYHQW RQ WKH 6WUDWIRUG FDPSXV RQ ³VLOYHU WVXQDPL´ RI WKH DJLQJ EDE\ 6HSWHPEHU WK QHDUO\ SHRSOH ERRPHU JHQHUDWLRQ $PHULFD LV MRLQHG 5RZDQ IDFXOW\ DQG VWDɱ WR XQGHUJRLQJ DQ XQSUHFHGHQWHG FHOHEUDWH WKH QHZ GHSDUWPHQW DQG WKH GHPRJUDSKLF VKLIW DV WKH VHOHFWLRQ RI 'U $QLWD &KRSUD DV WKH JHQHUDWLRQ WKDW ZRXOG QHYHU :LOOLDP * 5RKUHU (QGRZHG &KDLU JURZ ROGHU EHJLQV UHDFKLQJ LWV LQ *HULDWULFV UHWLUHPHQW \HDUV *HULDWULFV ´5RZDQ 8QLYHUVLW\ 5RZDQ620 'HDQ EHJDQ DW 'U 7KRPDV $ &DYDOLHUL 5RZDQ620 6FKRRO RI 2VWHRSDWKLF DV D VPDOO 0HGLFLQH KDV EHFRPH MXVW SRLQWHG WR VRPH RI WKH VWDWLVWLFV WKDW DUH GULYLQJ VXEVHFWLRQ WKH WK PHGLFDO VFKRRO WKLV FKDQJH LQFOXGLQJ WKH L-R: Dr. Ali A. Houshmand, President, Rowan University; Dr. Anita Chopra, Endowed Chair of new LQ WKH LQ WKH 8QLWHG 6WDWHV ħ DQG IDFW WKDW DSSUR[LPDWHO\ Department of Geriatrics & Gerontology and Director of the New Jersey Institute for Successful Aging; 'HSDUWPHQW Ms. Linda M. Rohrer, Trustee, William G. Rohrer Charitable Foundation, Chairman, Rowan University Board WKH ÀUVW LQ 1HZ -HUVH\ $PHULFDQV WXUQ RI 0HGLFLQH of Trustees; and Dr. Thomas A. Cavalieri, Dean, Rowan University School of Osteopathic Medicine at the HYHU\ GD\ D WUHQG WKDW September 30th ceremony.

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2TAB COURIER-POST, Thursday, October 16, 2014

Drug gives big survival boost against type of advanced breast cancer Women with HER2-positive tumors gained an average 16 more months of life with Perjeta, study finds

By E.J. MUNDELL HealthDay Adding the drug Perjeta to a standard medication, Herceptin, may give women with a form of advanced breast cancer a significant boost in survival, a new study finds.

The finding is limited to patients with tumors called HER2-positive that have spread (metastasized).

And experts say that this type of treatment-linked boost in survival — an average of nearly 16 extra months of life — is very rare in cancer research.

Dr. Stephanie Bernik, chief of surgical oncology at Lenox Hill Hospital in New York City, described the new findings as “extremely exciting.”

“Great strides have been made in treating breast cancer, and it is particularly encouraging that we now have additional treatment to offer patients with HER2-positive metastatic disease that extends survival,” she said.

“Treatment regimens continue to become more tailored to a patient’s individual cancer, lessening unwanted side effects from drugs that may not be beneficial, and focusing on treatments that have been shown to improve outcomes for a specific tumor,” added Bernik, who was not involved with the study.

Some breast tumor cells carry a “receptor” protein on their surface called HER2, which is thought to fuel the cancer.

However, certain HER2-targeted medications such as Herceptin and

CP-0010538588

Perjeta (pertuzumab) aim to interrupt this process, curbing the tumor’s spread.

According to the U.S. National Cancer Institute, about 20 percent of breast cancers are HER2-positive.

The study — funded by drugmaker Genentech and presented at the European Society for Medical Oncology meeting in Madrid, Spain — follows a positive report for Perjeta released in 2012. That trial suggested that patients with HER2-positive cancers might benefit, but more time was needed to discover just how big the benefit might be.

The study involved more than 800 women with advanced HER2-positive breast cancers whose illness had either never been treated, or who had returned for treatment after undergoing a different regimen.

Patients either received a combination of three drugs — Perjeta, Herceptin and docetaxel — or Herceptin,

docetaxel and a “dummy” drug (placebo). Patient outcomes were then tracked for a median of more than four years.

The researchers reported that people who took Perjeta along with the other two standard medications gained an average 15.7 months in survival (56.5 months versus 40.8 months). This was equivalent to a 32 percent reduction in the odds that the patient would die over the length of the trial, the authors noted.

“Adding Perjeta to treatment with Herceptin and chemotherapy resulted in the longest survival observed to date in a clinical study of people with HER2-positive metastatic breast cancer,” study lead author Dr. Sandra Horning, chief medical officer at Genentech, said in a company news release. She called the survival boost “a magnitude of improvement we rarely see in clinical trials in advanced cancer.”

0RUH LQIRUPDWLRQ 7KHUH·V PRUH RQ WUHDWLQJ +(5 SRVLWLYH EUHDVW FDQFHUV DW WKH 8 6 1DWLRQDO &DQFHU ,QVWLWXWH DW ZZZ FDQFHU JRY However, there were some downsides to taking Perjeta, which was approved by the U.S. Food and Drug Administration in 2012 for use against breast cancer. The study found that women taking Perjeta had higher rates of diarrhea, rash and a lowering of white blood cell counts compared to women taking only Herceptin and docetaxel.

And the study found that — for reasons that remain unclear — Perjeta only slowed the progression or worsening of the disease by an average of about 6 months, even though it extended overall survival

by much longer.

“This prolongation of survival is unprecedented, particularly in this group of patients with higher-risk disease,” said one of the study investigators, Dr. Paula Klein, assistant professor of medicine, hematology and medical oncology at Icahn School of Medicine at Mount Sinai in New York City.

The drug comes with a hefty price tag, though. According to The New York Times, patients in the United States can expect a bill of about $5,900 for a month’s supply of Perjeta.

That’s in addition to the $5,300 monthly cost of Herceptin, the newspaper said. Klein labeled such costs the “financial toxicity” of new cancer drugs.

Experts note that studies presented at medical meetings are typically considered preliminary until published in a peer-reviewed journal.