ACTA UNIV. SAPIENTIAE, ALIMENTARIA, 14 (2021) 14–43 DOI: 10.2478/ausal-2021-0002
The production methods of selenium nanoparticles B. Khandsuren1,2
J. Prokisch1,2
e-mail: b_khandsuren@muls.edu.mn
e-mail: jprokisch@agr.unideb.hu
1 Institute of Animal Science, Biotechnology and Nature Conversation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, Hungary 2 Doctoral School of Animal Science, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, Hungary
Abstract. In recent years, the application of selenium nanoparticles has been increasing in medicine, agriculture, engineering, and food science. Therefore, researchers are converting inorganic selenium sources into nano form by various methods. Particularly both probiotics and pathogenic bacterial strains have the ability to synthesize selenium nanoparticles under aerobic and anaerobic conditions. Amazingly, dose-dependent selenium nanoparticles have antibacterial activity against their own pathogenic producer, even when added externally. Also, plant extracts and conventional chemical reducing agents continue to make a significant contribution to the production of selenium nanoparticles in an economic, eco-friendly, simple, and rapid way. Biological and chemical methods are suitable for the biological applications of selenium nanoparticles such as functional food or nutritional supplements and nanomedicine. Keywords and phrases: selenium nanoparticles, bacteria, plants, fungi, reducing agents
1. Introduction Selenium is an essential nutrient element required for the production of amino acids and enzymes, reducing cell and tissue damage caused by free radicals in the human and animal body. However, not all living organisms can produce it, so it is necessary to be obtained from the diet; and there is a narrow gap between its essential and toxic effects. Naturally, selenium is found as inorganic selenium (selenate, selenite, selenide, elemental selenium) and organic selenium
