Understanding Motor neuron disease (MND)
● MND occurs when specialized nerve cells in the brain and spinal cord, called motor neurons, stop working properly.
● Motor Neuron diseases are a rare but severe form of neurodegenerative disease.
● It cause the motor nerves in the spine and brain to lose function over a span of time
● The two main types of motor neurons are upper motor neurons (UMN) and lower motor neurons (LMN)
● Also known as Amyotrophic Lateral Sclerosis (ALS), it is a rare neurodegenerative disease.
Motor Neuron Disease Symptoms
The symptoms are divided into three stages – early, middle and advanced.
Signs and symptoms in the early stage:
● Weakened grip, making it difficult to hold and pick up objects
and twitching
●
in arms and legs, leading to
and
● Muscle pain, cramps,
Weakness
clumsiness
stumbling ● Fatigue ● Slurred speech and difficulty swallowing ● Breathing trouble ● Weight loss due to loss of muscle mass ● Inappropriate emotional responses
Signs
and symptoms in the middle stage:
● Shrinking
of
muscles ● Joint pain ● Difficulty in movement ● Drooling and problems with swallowing ● Difficulty breathing ● Changes in personality and emotional states ● Memory and language problems
Signs and symptoms in the advanced stage: ● Little or no movement ● Trouble talking and swallowing ● Severe breathing problems ● May develop dementia ● Some people may also experience insomnia, anxiety, and depression
MND Diagnosis
A neurologist examines the person thoroughly by running a series of tests before determining MND, some of which are: ● Blood and urine tests ● MRI scan ● EMG (electromyography) and NCS (nerve conduction study) ● Muscle biopsy ● Lumbar puncture or spinal tap
MND Treatment
● The condition of the prognosis varies, depending on the patient’s type of MND and the age of symptom onset ● Supportive and symptomatic treatment can surely help ● One can take assistance from multidisciplinary clinics consisting of specialists from varied departments such as: ➢ physical therapy ➢ speech therapy ➢ occupational therapy ➢ respiratory therapy ➢ neurology
Stem cell therapy for MND
● Stem Cell Therapy is a potent approach for treating MND and its vitalizing effects, both paracrine and somatic
● This treatment helps to improve the repairing mechanism of diseased, dysfunctional, or injured tissue with the help of stem cells
● It is proven to mitigate symptoms, slow the progression of the disease, improve the quality of life and increase survival
● The beneficial effects of this therapy do not just affect the cells, but are also beneficial to trophic interventions
● It mitigates the symptoms of traumatic injuries, autoimmune, inflammatory, neurological, and orthopedic diseases
● It helps to reduce inflammation and delay progression
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