Fine arts portfolio

Alexander Farley U. Pennsylvania - B.A. Biology, B.A. Fine Arts California Institute of Technology - Ph.D. expected

Candidate for Master of Architecture I

Table of Contents 1. Design and Sculpture 2. Figure Drawing self portrait

medium: graphite on paper size: 24� x 18� year: 1997

3. Cityscapes 4. Curriculum Vitae

Design and Sculpture

Alexander Farley

urban narrative book medium: gouache size: 12� x 60� year: 1999

Fig 1.

Doctoral Thesis Figures Fig 2.

Sprague and Bjorkman

Farley and Bjorkman

Fig 4.

Fig 3.

Fig 1. Bipolar bridging complex of an anti-HSV IgG (green) bound to a membrane-bound HSV antigen (brown) and mediated by HSV gE-gI (blue and red) Fig 2. (A) Schematic of an antibody bipolar bridged complex containing gE-gI, anti-gDhFc, and gD. (B) Schematic of anti-gDmFc bound to gD, but not gE-gI. (C) Schematic of 2G12 bound to gE-gI, but not gD. Fig 3. HeLa cells transiently transfected with the gD-CerFP expression vector and then fixed and processed for immunofluoresence. anti-gDmFc (green) and intracellular marker(red); EEA1 (left), Rab11 (middle), or LAMP2 (right).

Farley and Bjorkman

Farley and Bjorkman

Fig 4. Quantitative colocalization analysis to compare gD-CerFP localization in gE-gI-negative cells in the presence and absence of antigD antibodies.

Alexander Farley

polymorphisms and mutations

illuminated phage logos

medium: wood and frosted acrylic size: 48� x 48� year: 2009

spider

material: douglas fir size: 48” x 48” x 36” year: 2009

Figure Drawing

shoulder anatomy medium: intaglio size: 18� x 24� year: 2000

Alexander Farley

figure

medium: conte crayon on paper size: 24� x 24� year: 1997

Alexander Farley

woman

medium: charcoal on paper size: 24” x 18” year: 2000

woman

medium: charcoal on paper size: 18” x 24” year: 2000

Cityscapes

blue line subway medium: oil on board size: 12” x 19.4” year: 2000

Alexander Farley

2100 chestnut street medium: oil on board size: 12” x 19.4” year: 2001

Alexander Farley

spruce street market

medium: oil on linen | size: 36” x 48” | year: 2000 - 2007

Alexander Farley

30th street station medium: oil on board size: 12” x 48” year: 2001

sansom street

medium: oil on board size: 12� x 19.4� year: 2001

Alexander Farley

pyramid building I medium: oil on board size: 12” x 19.4” year: 2006

pyramid building II medium: oil on board size: 12” x 19.4” year: 2006

Curriculum Vitae

A LEXANDER F ARLEY

900 Orlando Place, San Marino, CA 91180 / 626.429.2280 / afarley@gmail.com

E D U C AT I O N California Institute of Technology, Pasadena, CA

2003 – 2010

University of Pennsylvania, Philadelphia, PA

1997 – 2001

PhD (expected) in Biology, Specialization: Virology, Biochemistry, and Cell Biology (Intracellular trafficking of a bipolar bridged complex of HSV-1 gE-gI, IgG, and a viral antigen) Bachelor of Arts in Fine Arts and Bachelor of Arts in Biology with Honors

HONORS Group Exhibitions: New Artist Summer Group Show, Gross McCleaf Gallery; Senior Thesis, Cityscapes, Meyerson Gallery Awards: Dean’s Prize (Fine Arts); Rose Undergraduate Research Award; Neysa Cristol Adams Prize in Biology Fellowships and Grants: College Alumni Society Research Grant; Department of Energy - Energy Research Undergraduate Laboratory Fellowship; Bristol-Myers Squibb Research Fellowship

P R O F E S S I O N AL E X P E R I E N C E Bjorkman Laboratory, California Institute of Technology, Pasadena, CA — Graduate Student

Researched viral-encoded receptors responsible for Herpes Simplex Virus immune evasion Created human cell line to inducibly express HSV glycoproteins gD, gE, and gI Showed that HSV receptors gE and gI are able to internalize antibodies Measured binding affinity of herpes virus antibody receptors to different classes of antibodies

Kazazian Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA — Technician Researched polymorphisms responsible for differences in L1 mobile DNA element length Discovered that L1 activity positively correlates with genomic insertion length Helped to analyze differences in active L1’s contribution to the human genome Helped to create germline based mouse model for L1 activity Bunick Laboratory, Oak Ridge National Laboratory, Oak Ridge, TN — Summer Fellow

2004 – Present

1999 – 2003

1999 – 1999

Researched high resolution 3D x-ray crystal structure of the nucleosome core particle Helped create protein expression system to produce milligrams quantities of histone H4

P U B L I C AT I O N S Technical Scientific Papers — Author Sprague ER, Reinhard H, Cheung EJ, Farley AH, Trujillo RD, Hengel H, Bjorkman PJ, The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G., J Virol. 2008 Apr;82(7):3490-9. Epub 2008 Jan 23 Farley AH, Luning Prak ET, Kazazian HH Jr, More Active Human L1 Retrotransposons Produce Longer Insertions. Nucleic Acids Res. 2004 Jan 23;32(2):502-10. Print 2004.

Weinzweig J, Kirschner RE, Farley A, Reiss P, Hunter J, Whitaker LA, Bartlett SP, Metopic synostosis: Defining the Temporal Sequence of Normal Suture Fusion and Differentiating It From Synostosis on the Basis of Computed Tomography Images. Plast Reconstr Surg. 2003 Oct;112(5):1211-8 Brouha B, Schustak J, Badge RM, Lutz-Prigge S, Farley AH, Moran JV, Kazazian HH Jr, Hot L1s Account for the Bulk of Retrotransposition in the Human Population. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5280-5. Epub 2003 Apr

SKILLS

AN D I N T E R E S T S

Computer Skills: Linux systems administration, bash, HTML, C, Python, Max/MSP, Adobe Photoshop, InDesign, Illustrator, Microsoft Office, Ableton Live Interests: hiking, painting, music production, DJing, travel (Japan, England, France, Netherlands, Austria, Mexico, Canada, Portugal)