Alexander Farley U. Pennsylvania - B.A. Biology, B.A. Fine Arts California Institute of Technology - Ph.D. expected
Candidate for Master of Architecture I
Table of Contents 1. Design and Sculpture 2. Figure Drawing self portrait
medium: graphite on paper size: 24� x 18� year: 1997
3. Cityscapes 4. Curriculum Vitae
Design and Sculpture
Alexander Farley
urban narrative book medium: gouache size: 12� x 60� year: 1999
Fig 1.
Doctoral Thesis Figures Fig 2.
Sprague and Bjorkman
Farley and Bjorkman
Fig 4.
Fig 3.
Fig 1. Bipolar bridging complex of an anti-HSV IgG (green) bound to a membrane-bound HSV antigen (brown) and mediated by HSV gE-gI (blue and red) Fig 2. (A) Schematic of an antibody bipolar bridged complex containing gE-gI, anti-gDhFc, and gD. (B) Schematic of anti-gDmFc bound to gD, but not gE-gI. (C) Schematic of 2G12 bound to gE-gI, but not gD. Fig 3. HeLa cells transiently transfected with the gD-CerFP expression vector and then fixed and processed for immunofluoresence. anti-gDmFc (green) and intracellular marker(red); EEA1 (left), Rab11 (middle), or LAMP2 (right).
Farley and Bjorkman
Farley and Bjorkman
Fig 4. Quantitative colocalization analysis to compare gD-CerFP localization in gE-gI-negative cells in the presence and absence of antigD antibodies.
Alexander Farley
polymorphisms and mutations
illuminated phage logos
medium: wood and frosted acrylic size: 48� x 48� year: 2009
spider
material: douglas fir size: 48” x 48” x 36” year: 2009
Figure Drawing
shoulder anatomy medium: intaglio size: 18� x 24� year: 2000
Alexander Farley
figure
medium: conte crayon on paper size: 24� x 24� year: 1997
Alexander Farley
woman
medium: charcoal on paper size: 24” x 18” year: 2000
woman
medium: charcoal on paper size: 18” x 24” year: 2000
Cityscapes
blue line subway medium: oil on board size: 12” x 19.4” year: 2000
Alexander Farley
2100 chestnut street medium: oil on board size: 12” x 19.4” year: 2001
Alexander Farley
spruce street market
medium: oil on linen | size: 36” x 48” | year: 2000 - 2007
Alexander Farley
30th street station medium: oil on board size: 12” x 48” year: 2001
sansom street
medium: oil on board size: 12� x 19.4� year: 2001
Alexander Farley
pyramid building I medium: oil on board size: 12” x 19.4” year: 2006
pyramid building II medium: oil on board size: 12” x 19.4” year: 2006
Curriculum Vitae
A LEXANDER F ARLEY
900 Orlando Place, San Marino, CA 91180 / 626.429.2280 / afarley@gmail.com
E D U C AT I O N California Institute of Technology, Pasadena, CA
2003 – 2010
University of Pennsylvania, Philadelphia, PA
1997 – 2001
PhD (expected) in Biology, Specialization: Virology, Biochemistry, and Cell Biology (Intracellular trafficking of a bipolar bridged complex of HSV-1 gE-gI, IgG, and a viral antigen) Bachelor of Arts in Fine Arts and Bachelor of Arts in Biology with Honors
HONORS Group Exhibitions: New Artist Summer Group Show, Gross McCleaf Gallery; Senior Thesis, Cityscapes, Meyerson Gallery Awards: Dean’s Prize (Fine Arts); Rose Undergraduate Research Award; Neysa Cristol Adams Prize in Biology Fellowships and Grants: College Alumni Society Research Grant; Department of Energy - Energy Research Undergraduate Laboratory Fellowship; Bristol-Myers Squibb Research Fellowship
P R O F E S S I O N AL E X P E R I E N C E Bjorkman Laboratory, California Institute of Technology, Pasadena, CA — Graduate Student
Researched viral-encoded receptors responsible for Herpes Simplex Virus immune evasion Created human cell line to inducibly express HSV glycoproteins gD, gE, and gI Showed that HSV receptors gE and gI are able to internalize antibodies Measured binding affinity of herpes virus antibody receptors to different classes of antibodies
Kazazian Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA — Technician Researched polymorphisms responsible for differences in L1 mobile DNA element length Discovered that L1 activity positively correlates with genomic insertion length Helped to analyze differences in active L1’s contribution to the human genome Helped to create germline based mouse model for L1 activity Bunick Laboratory, Oak Ridge National Laboratory, Oak Ridge, TN — Summer Fellow
2004 – Present
1999 – 2003
1999 – 1999
Researched high resolution 3D x-ray crystal structure of the nucleosome core particle Helped create protein expression system to produce milligrams quantities of histone H4
P U B L I C AT I O N S Technical Scientific Papers — Author Sprague ER, Reinhard H, Cheung EJ, Farley AH, Trujillo RD, Hengel H, Bjorkman PJ, The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G., J Virol. 2008 Apr;82(7):3490-9. Epub 2008 Jan 23 Farley AH, Luning Prak ET, Kazazian HH Jr, More Active Human L1 Retrotransposons Produce Longer Insertions. Nucleic Acids Res. 2004 Jan 23;32(2):502-10. Print 2004. Weinzweig J, Kirschner RE, Farley A, Reiss P, Hunter J, Whitaker LA, Bartlett SP, Metopic synostosis: Defining the Temporal Sequence of Normal Suture Fusion and Differentiating It From Synostosis on the Basis of Computed Tomography Images. Plast Reconstr Surg. 2003 Oct;112(5):1211-8 Brouha B, Schustak J, Badge RM, Lutz-Prigge S, Farley AH, Moran JV, Kazazian HH Jr, Hot L1s Account for the Bulk of Retrotransposition in the Human Population. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5280-5. Epub 2003 Apr
SKILLS
AN D I N T E R E S T S
Computer Skills: Linux systems administration, bash, HTML, C, Python, Max/MSP, Adobe Photoshop, InDesign, Illustrator, Microsoft Office, Ableton Live Interests: hiking, painting, music production, DJing, travel (Japan, England, France, Netherlands, Austria, Mexico, Canada, Portugal)