SOFOSBUVIR / VELPATASVIR (EPCLUSA)
Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed dose combination medication for the treatment of hepatitis C. It combines sofosbuvir and velpatasvir.It is more than 90% effective for hepatitis C genotypes one through six.
Medical Uses:
A single tablet regimen is used for adults with genotype 1–6 chronic hepatitis C virus (HCV) infection.
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Side Effects:
Common side effects (in more than 10% of people) are headache, fatigue and nausea. Breathing difficulty Sleeping trouble Loss of appetite
Precautions:
All patients should be tested for evidence of current/prior HBV infection before starting this drug HBV reactivation has been reported during or after completion of HCV direct-acting antiviral therapy in HCV/HBV-coinfected patients who were not receiving HBV antiviral therapy; some cases resulted in fulminant hepatitis, hepatic failure, and death. HCV/HBV-coinfected patients should be monitored for hepatitis flare or HBV reactivation during HCV therapy and posttherapy follow-up; appropriate patient management for HBV infection should be started as clinically indicated.
Sofosbuvir and Velpatasvir Brand Names:
Sofosbuvir and Velpatasvir may be found in some form under the following brand names:
Epclusa Sofosbuvir and Velpatasvir Food Interactions:
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of sofosbuvir and velpatasvir, there are no specific foods that you must exclude from your diet when receiving this medication.
Sofosbuvir and Velpatasvir and Pregnancy:
Tell your doctor if you are pregnant or plan to become pregnant. No adequate human data are available to establish whether or not sofosbuvir and velpatasvir poses a risk to pregnancy outcomes. In animal studies, no evidence of adverse developmental outcomes was observed with the components of sofosbuvir and velpatasvir.
Sofosbuvir and Velpatasvir Overdose:
If you take too much sofosbuvir and velpatasvir, call your healthcare provider or go to the nearest hospital emergency room right away.
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