HEPCVEL-Hepatitis C Drug

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Hepatitis C Drug- Hepcvel(Sofosbuvir/Velpatasvir) Description Of Hepcvel: 

Hepcvel Combination of Sofosbuvir 400mg&Velpatasvir 100mg which is a Cipla product get approved by FDA.

The combination of sofosbuvir & Velpatasvir is highly effective in chronic hepatitis C viral infection caused by genotypes I to VI.

Hepcvel is not a curable medication; it is used for diminishing the disease progression by depleting the multiplication of virus in the body.

Hepcvel tablets are prescription medicine which is used only under the guidance of medical practitioner. Brand name : Hepcvel Ingredient : Sofosbuvir 400mg/Velpatasvir 100mg Tablet Count: 28 Tablets Company Name : Cipla

Hepcvel Tablet Uses: 

Hepcvel(Sofosbuvir/Velpatasvir) used to treat Chronic Hepatitis C,a viral infection of the liver.

Hepcvel Tablet Side effects: 

Headache

Fatigue

Nausea

Asthenia

Insomnia

Diarrhea


Pharmacokinetics of Hepcvel Absorption The maximal peak plasma concentration time of; 

Sofosbuvir 0.5 to 1 hour

Velpatasvir 3 hours

Distribution After absorption occurs, Hepcvel get binds to human plasma protein by; 

Sofosbuvir 61 to 65%

Velpatasvir >99.5%

The blood plasma ratio of Hepcvel; 

Sofosbuvir: 0.7; Velpatasvir: 0.52 to 0.67

Metabolism 

The metabolism of Hepcvel is occurs widely in liver

Sofosbuvir: cathepsin A, carboxyl esterase 1 or HINT1

Velpatasvir: CYP2B6, CYP2C8, or CYP3A4

Indication of Hepcvel Tablet: 

Hepcvel tablets are primarily indicated for the treatment of chronic hepatitis C viral infection associated with genotype I to VI.

Hepcvel is indicated for the conditions; 

Patients without cirrhosis or with compensated cirrhosis

Patients with decompensated cirrhosis

Dosage & Administration of Hepcvel: Before initiating the treatment; 

Patient’s HBsAg & anti-HBc levels should be examined before starting the therapy with hepcvel tablets.

The recommended dose of Hepcvel tablets; 

Hepcvel tablets are two medicine fixed dose combination consists of 400mg of sofosbuvir & 100mg of Velpatasvir.

Hepcvel is a single use tablet.

Warning & precautions


This fatal case should be occurred in the patients with HCV/HBV co infection & also who receiving anti-HCV agents but not getting anti-HBV treatment.

Before starting the treatment, patient should be tested by measuring HBsAg 7 anti-HBc counts.

Monitor the liver function test.

Initiate the HBV infection management.

Pregnancy & lactation 

Hepcvel pregnancy category is B

Hepcvel with ribavirin pregnancy category is X

This combination should not be used in pregnancy period.

Breast feeding should not be recommended.

Storage 

Hepcvel tablet container should be stored at temperature below 30oC.

Keep the container away from heat, moisture & light.

Missed dose 

In case of missed dose condition, patients should be consult with medical adviser &

 

follow the instructions. Maintain the regular dosing schedule. Avoid self medication.

Buy Hepvel Tablet Online:  

Apple Pharmaceuticals is a leading provider of India offering Hepatitis C quality medicines around the world offering affordable Hepvel. It will provide generic hepatitis medicines in the US, Russia, Europe, China, Japan, Romania, Italy, Hungary, Bulgaria, Poland, Czech Republic, Germany, UK, Slovakia, Austria, Ukraine, Kazakhstan and Turkey. Price, authentic quality, Timely delivery, Customer satisfaction 100%.

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