Resof L-Hepatitis Medicine

Resof L Tablets:  Resof L is Combination of Ledipasvir and Sofosbuvir.It is used to treat Chronic Hepatitis C Virus.  Resof L is used in a combination with another drug, to prevent the spread of HCV throughout the body.  Resof L manufactured by Dr. Reddy's comes in a pack of 28 tablets.

Uses Of Resof L Tablet:  Resof L (Ledipasvir/Sofosbuvir) is a very effective HCV drug that is used to treat chronic hepatitis C (ongoing viral infection that damages the liver).  Resof L is used in a combination with another drug, to prevent the spread of HCV throughout the body.

Side Effects Of Resof L Tablet:  Fatigue

 Nausea  Headache  Anemia  Insomnia  Sleeping Problem

Resof L Tablet Works:  Resof L is a Direct Acting Antiviral (DAA) medication.  DAAs are a group of medications that directly block the ability of the hepatitis C virus to make copies of itself.  Resof L is a combination of two direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) life cycle.  One is Sofosbuvir, which is a nucleotide polymerase inhibitor, and the other is Ledipasvir, which is an NS5A inhibitor.  Sofosbuvir interferes with the reproduction of the virus’s genetic material, stopping the production of new Hep C virus.  Ledipasvir interferes with a protein needed to complete the Hep C virus life cycle in the liver cell.

Safety Information of Resof L: Alcohol - Interaction with alcohol is unknown. Please consult your doctor.

Pregnancy -Resof-L Tablet is safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

Lactation -Resof-L Tablet is safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Driving -Dont drive unless you are feeling well.Resof-L Tablet, when taken together with other medicines for the treatment of hepatitis c infection.

How to Use Resof L Tablet:  Take this medicine in the dose and duration as advised by your doctor.  Swallow it as a whole. Do not chew, crush or break it. 

Resof-L Tablet should be taken with or without food, but it is better to take it at a fixed time.

Pharmacology of Resof L Tablet: Sofosbuvir:  Sofosbuvir is a nucleotide inhibitor; especially prohibits HCV NS5B RNA polymerase,  It is metabolized into active form which is known as triphosphate uridine analogue.  Sofosbuvir is inserted into viral RNA by NS5B polymerase and performed as chain terminator. 

Sofosbuvir is interfere in viral replication process

Ledipasvir:  Ledipasvir is a NS5A, which is a protein essential for viral multiplication and association of HCV virions.  Ledipasvir interfere with NS5A protein activity and terminates the viral replication.

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