Resof L Tablets: Resof L is Combination of Ledipasvir and Sofosbuvir.It is used to treat Chronic Hepatitis C Virus. Resof L is used in a combination with another drug, to prevent the spread of HCV throughout the body. Resof L manufactured by Dr. Reddy's comes in a pack of 28 tablets.
Uses Of Resof L Tablet: Resof L (Ledipasvir/Sofosbuvir) is a very effective HCV drug that is used to treat chronic hepatitis C (ongoing viral infection that damages the liver). Resof L is used in a combination with another drug, to prevent the spread of HCV throughout the body.
Side Effects Of Resof L Tablet: Fatigue
Nausea Headache Anemia Insomnia Sleeping Problem
Resof L Tablet Works: Resof L is a Direct Acting Antiviral (DAA) medication. DAAs are a group of medications that directly block the ability of the hepatitis C virus to make copies of itself. Resof L is a combination of two direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) life cycle. One is Sofosbuvir, which is a nucleotide polymerase inhibitor, and the other is Ledipasvir, which is an NS5A inhibitor. Sofosbuvir interferes with the reproduction of the virus’s genetic material, stopping the production of new Hep C virus. Ledipasvir interferes with a protein needed to complete the Hep C virus life cycle in the liver cell.
Safety Information of Resof L: Alcohol - Interaction with alcohol is unknown. Please consult your doctor. Pregnancy -Resof-L Tablet is safe to use during pregnancy. Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor. Lactation -Resof-L Tablet is safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving -Dont drive unless you are feeling well.Resof-L Tablet, when taken together with other medicines for the treatment of hepatitis c infection. How to Use Resof L Tablet: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Resof-L Tablet should be taken with or without food, but it is better to take it at a fixed time.
Pharmacology of Resof L Tablet: Sofosbuvir: Sofosbuvir is a nucleotide inhibitor; especially prohibits HCV NS5B RNA polymerase, It is metabolized into active form which is known as triphosphate uridine analogue. Sofosbuvir is inserted into viral RNA by NS5B polymerase and performed as chain terminator.
Sofosbuvir is interfere in viral replication process
Ledipasvir: Ledipasvir is a NS5A, which is a protein essential for viral multiplication and association of HCV virions. Ledipasvir interfere with NS5A protein activity and terminates the viral replication.
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