We use most of all to indicate that something happens or is true to a greater extent than anything else. : especially, in particular, above all. Examples: His music was the thing he loved most of all.
Most of all, I just felt sad that it was over. She said she wanted most of all to be fair. The kids loved the circus, and most of all the clowns. Excellent experience today, everyone was welcoming, friendly and most of all informative.