The thesis "The growing scenario: a generative ecosystem for a bioactive city" explores the potential of biologically inspired digital design at the urban scale. Efficient biological systems that evolved over the course of time are proving to be useful models for man and his research. How can we contribute to human and environmental good by learning about material and design from nature? We would like to demonstrate there is a way to make things more efficient and effective: using the right (high) technology and processes with zero waste, zero mess and at a very low cost, and investing into human and natural resources, we can morph at architectural scale. Our goal is to enhance the relationship between the human, the built and the natural environments by employing design principles inspired by nature and implementing them in the invention of digital design technologies.