Rituximab treatment for non-Hodgkin lymphoma Non-Hodgkin's lymphoma is a cancer of the immune system. The condition of non-Hodgkin's lymphoma mainly occurs in lymphocytes, a type of WBC (White Blood Cell). These cells are a major part of the immune system and believed to help defend the body from infection. In order to treat NHL, Rituximab 500mg Injection is widely prescribed. It should be examined on weekly basis for 4-8 weeks .It is initially administered on weekly basis for 4-8 weeks. Side effects of rituximab for non-Hodgkin lymphoma are fever, cough, rash, and back pain.