EEBMB Announcement by ARTION Conferences & Events

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας 23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology November 23-25, 2018 Imperial Hotel, Larissa

Πρόγραμμα - Programme

Περιεχόμενα | Table of Contents Οργανωτική & Επιστημονική Επιτροπή | Organizing & Scientific Committee �� 3 Διοικητικό Συμβούλιο ΕΕΒΜΒ | Board of directors HSBMB �� 3 Χαιρετισμός Προέδρων | Presidents’ greeting �� 4 Χρήσιμες Πληροφορίες | Useful information �� 5 Κόστος Εγγραφής | Registration Fees �� 5 Πληροφορίες Επιστημονικού Προγράμματος | Information on the Scientific Program �� 6 Προσκεκλημένοι Ομιλητές | Invited Speakers �� 7 Επιστημονικό Πρόγραμμα | Scientific Program �� 9 Αναρτημένες Ανακοινώσεις | Poster Sessions �� 23 Ευρετήριο | Index �� 45 Εκθεσιακός χώρος | Exhibition Area �� 58 Χορηγοί | Sponsors �� 59

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

Οργανωτική & Επιστημονική Επιτροπή

Imperial Hotel, Larissa www.eebmb-congress.gr

Organizing & Scientific Committee

Πρόεδρος του Συνεδρίου Γιώργος Σίμος Αντιπρόεδρος Δημήτρης Λεωνίδας Μέλη Ελένη Γεωργάτσου Παναγιώτης Λιάκος Κώστας Ματθιόπουλος Νίκος Μπαλατσός Ηλίας Μυλωνής Γεώργιος Παπαδόπουλος Καλλιόπη Παπαδοπούλου Ευφροσύνη Παρασκευά Βασιλική Σκαμνάκη Ανδρέας Τσακάλωφ Γεωργία Χαχάμη Άννα-Μαρία Ψαρρά

President of the Congress: George Simos Vice president: Demetres Leonidas Members: Eleni Georgatsou Panagiotis Liakos Kostas Mathiopoulos Nikos Balatsos Ilias Mylonis Georgios Papadopoulos Kalliope K. Papadopoulou Efrosyni Paraskeva Vassiliki T. Skamnaki Andreas Tsakalof Georgia Chachami Anna-Maria Psarra

Διοικητικό Συμβούλιο ΕΕΒΜΒ Πρόεδρος: Αντιπρόεδρος: Γενικός Γραμματέας: Ταμίας: Μέλη:

November 23-25, 2018

Board of directors HSBMB Chairman: Vice president: General secretary: Treasurer: Members:

Ν. Καραμάνος Δ. Κλέτσας Δ. Σγούρας Β. Κωστούρου Γ. Μόσιαλος Α. Μουστάκας Δ. Καρδάσης

N. Karamanos D. Kletsas D. Sgouras V. Kostourou G. Mossialos A. Moustakas D. Kardasis

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Χαιρετισμός Προέδρων

Presidents’ greeting

Αγαπητοί Συνάδελφοι,

Dear Colleagues,

Με χαρά σας καλωσορίζουμε στο 69 Πανελλήνιο Συνέδριο της Ελληνικής Εταιρείας Βιοχημείας και Μοριακής Βιολογίας (EEBMB) που πραγματοποιείται στη Λάρισα, στο Ξενοδοχείο Imperial, 23-25 Νοεμβρίου 2018.

It is our pleasure to welcome you to the 69th Annual Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB) which is taking place in Larissa, at Hotel Imperial, from November 23rd to November 25th, 2018.

Όπως κάθε χρονιά, το Συνέδριο φέρνει σε επαφή ερευνητικές ομάδες Ελλήνων Επιστημόνων που δραστηριοποιούνται σε διάφορους τομείς των Βιοεπιστημών, στην Ελλάδα αλλά και στο εξωτερικό, συμβάλλει στην αλληλεπίδραση ή και στις προοπτικές συνεργασίας μεταξύ τους, αναδεικνύει σημαντικές προσπάθειες των νέων Ελλήνων ερευνητών και δίνει τον σφυγμό από το πρόσφατο ερευνητικό έργο καταξιωμένων ερευνητών από την Ελλάδα και τον διεθνή χώρο. Το Συνέδριο είναι ανοικτό σε όλη τη θεματολογία της σύγχρονης Βιοχημείας και Μοριακής Βιολογίας. Μεταξύ των θεματικών ενοτήτων του Συνεδρίου περιλαμβάνονται: η Δομή και Λειτουργία Μακρομορίων, η Ανάπτυξη και Κυτταρική Επικοινωνία, η Κυτταρική Οργάνωση και Λειτουργία, η Γονιδιακή Έκφραση και η Βιολογία του RNA, η Μοριακή και Κυτταρική Βάση των Ασθενειών, η Βιολογία Συστημάτων, η Βιοπληροφορική και η Βιοτεχνολογία. George Simos

As every year, the HSBMB Conference is bringing together and contributes to the interaction between research teams of Greek scientists working in various fields of life sciences, both in Greece and abroad, presents the work of young Greek researchers and highlights the recent research advances of nationally and internationally established scientists. The 69th HSBMB Conference is open to all modern fields of Biochemistry and Molecular Biology including Structure and Function of Macromolecules, Development & Cellular Signaling, Cellular Organization and Function, Gene Expression & RNA Biology, Molecular & Cellular Basis of Human Disease, Systems Biology & Bioinformatics and Biotechnology.

Renowned scientists from Greece and abroad participate in this year’s Conference as invited speakers: Sir Peter Ratcliffe Nikos Karamanos (Oxford University), Anne Osbourn (John Innes Centre), David Stuart (Oxford University), Antonis Koromilas (McGill University), Othon Iliopoulos (Harvard Medical School), Nikos Kyrpides (Joint Genome Institute, Berkley), George Spyroulias (University of Patras), Christos Tsatsanis (University of Crete), Christos Zervas (BRFAA), Katerina Katsani (Democritus University of Thrace) and Gregoris Amoutzias (University of Thessaly).

Στο φετινό Συνέδριο συμμετέχουν ως προσκεκλημένοι ομιλητές διακεκριμένοι επιστήμονες από την Ελλάδα και το εξωτερικό, όπως οι: Sir Peter Ratcliffe (Oxford University), Anne Osbourn (John Innes Centre), David Stuart (Oxford University), Αντώνης Κορομηλάς (McGill University), Όθων Ηλιόπουλος (Harvard Medical School), Νίκος Κυρπίδης (Joint Genome Institute, Berkley), Γεώργιος Σπυρούλιας (Πανεπιστήμιο Πατρών), Χρήστος Τσατσάνης (Πανεπιστήμιο Κρήτης), Χρήστος Ζέρβας (IIBEAA), Κατερίνα Κατσάνη (Δημοκρίτειο Πανεπιστήμιο) και Γρηγόρης Αμούτζιας (Πανεπιστήμιο Θεσσαλίας).

The Conference also includes a Special Session devoted to honoring the memory of Prof. Fotis Kafatos (ex-director of EMBL and ERC) who recently passed away. Speakers of this Session will be Iain Mattaj (EMBL, Heidelberg), Spyros Georgatos (University of Ioannina) and George Christophides (Imperial College London).

Το Συνέδριο περιλαμβάνει και μια ειδική συνεδρία αφιερωμένη στην μνήμη του Καθηγητή Φώτη Καφάτου, στην οποία συμμετέχουν ως ομιλητές οι Iain Mattaj (EMBL), Σπύρος Γεωργάτος (Πανεπιστήμιο Ιωαννίνων) και Γιώργος Χριστοφίδης (Imperial College, London).

The Conference will also like to honor the memory of the recently deceased members of HSBMB, Ioannis Georgatsos (Professor Emeritus, AUTH), Dimitrios Kalpaxis (Professor of Biochemistry, Univ. of Patras), an active professor and researcher that prematurely passed away, as well as Georgios Paleologos (Medical School, Athens University) and Eleftherios Sideris (NCSR «Demokritos»). All of them had a great contribution to the development of the Biochemical Science in Greece and the founding, establishment and subsequent success of HSBMB.

Το Συνέδριο επίσης τιμά τη μνήμη των πρόσφατα εκλιπόντων μελών της ΕΕΒΜΒ, Ιωάννη Γεωργάτσου (Ομότιμοu Καθηγητή Βιοχημείας, ΑΠΘ), Δημήτρη Καλπαξή (Καθηγητή Βιοχημείας Παν. Πατρών) ενεργού δασκάλου και ερευνητή που χάθηκε πρόωρα, καθώς και των Γεωργίου Παλαιολόγου (Ιατρική Σχολή, ΕΚΠΑ) και Ελευθέριου Σιδέρη (ΕΚΕΦΕ “ΔΗΜΟΚΡΙΤΟΣ”). Όλοι τους συνέβαλαν τα μέγιστα τόσο στην ανάπτυξη της επιστήμης της Βιοχημείας στην Ελλάδα όσο και στην ίδρυση, λειτουργία και επιτυχία της ΕΕΒΜΒ.

Linked to the 69th HSBMB Conference, the Forum of Young Scientists of the HSBMB, a previously very successful event, is also organized for the 6th time by an independent committee of young researchers. The 6th Forum of Young Scientists of the HSBMB takes place in Larissa, at Hotel Imperial, on November 22th, 2018.

Παράλληλα με το 69ο Συνέδριο, συνεχίζεται, για 6η χρονιά, ο πολύ επιτυχημένος θεσμός της διεξαγωγής της Ημερίδας Νέων Επιστημόνων, μελών της ΕΕΒΜΒ, η οποία οργανώνεται ανεξάρτητα, από μία επιτροπή νέων ερευνητών. Η 6η Ημερίδα Νέων Επιστημόνων της ΕΕΒΜΒ πραγματοποιείται επίσης στο Ξενοδοχείο Imperial, στις 22 Νοεμβρίου 2018.

We would like to thank you all for your presence and your active participation in the Conference.

Σας ευχαριστούμε όλους για τη παρουσία σας και την ενεργή συμμετοχή σας στο Συνέδριο.

Γιώργος Σίμος

Νίκος Καραμάνος

George Simos

Nikos Karamanos

Πρόεδρος Οργανωτικής & Επιστημονικής Επιτροπής

Πρόεδρος της ΕΕΒΜΒ

Chairman of the Organizing & Scientific Committee

President of HSBMB

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Χρήσιμες Πληροφορίες

Useful information

Χρήσιμες Πληροφορίες

Official language of the conference

Η επίσημη γλώσσα του Συνεδρίου είναι η Ελληνική. Οι περιλήψεις κατατίθενται μόνο στην αγγλική γλώσσα. Οι παρουσιάσεις μπορούν να γίνουν στα Ελληνικά ή στα Αγγλικά. Παρακαλούμε να ληφθεί υπόψη ότι πολλοί από τους ξένους προσκεκλημένους ομιλητές θα παρακολουθήσουν τις εργασίες του συνεδρίου.

The official language of the conference is Greek. Summaries will be submitted only in English. Presentations can be in Greek or in English. Please note that many of the foreign invited speakers will attend the conference proceedings.

Opening Ceremony

Εναρκτήρια Τελετή

The Opening Ceremony of the Conference will take place on Friday 23rd November 2018 at Hotel Imperial, Larissa.

Η Εναρκτήρια Τελετή του Συνεδρίου θα γίνει την Παρασκευή 23 Νοεμβρίου 2018 στο ξενοδοχείο Larissa Imperial.

Exhibition

Έκθεση

A scientific equipment and supplies exhibition will be held during the conference.

Κατά τη διάρκεια του Συνεδρίου θα λειτουργήσει έκθεση επιστημονικού εξοπλισμού και αναλωσίμων.

Κόστος Εγγραφής Κατηγορία Μέλη

Registration Fees Έως 08/10/2018

Από 08/10/2018 και επιτόπου

Category

55 €

70 €

Members

Until 08/10/2018

After 8/10/2018 and on site

55 €

70 €

Αρωγά Μέλη

35 €

50 €

Affiliated Member

35 €

50 €

Μή μέλη

100 €

135 €

Non-members

100 €

135 €

Μεταπτυχιακοί φοιτητές*

35 €

50 €

Postgraduate students*

35 €

50 €

Προπτυχιακοί φοιτητές **

20 €

30 €

Undergraduate students **

20 €

30 €

Συμπλήρωμα Εγγραφής ***

10 €

Registration Supplement Fee ***

10 €

* Η κατηγορία αυτής της εγγραφής αφορά μεταπτυχιακούς φοιτητές που δεν παρουσιάζουν εργασία. Οι μεταπτυχιακοί φοιτητές που παρουσιάζουν εργασία θα πρέπει να υποβάλλουν αίτηση εγγραφής στην ΕΕΒΜΒ ως Αρωγά Μέλη και να εγγραφούν στην αντίστοιχη κατηγορία εγγραφής (Αρωγά Μέλη).

* The category of this entry concerns postgraduate students who do not present a paper. Postgraduate students presenting a paper should apply for registration to HSBMB as Affiliated Members and register in the relevant registration category (Affiliated Members).

Η εγγραφή περιλαμβάνει:

The registration includes:

** Η εγγραφή προπτυχιακών φοιτητών περιλαμβάνει

** Undergraduate students registration includes:

*** Επιλέγοντας το Συμπλήρωμα Εγγραφής το Συμπλήρωμα Εγγραφής στο συνεδριακό υλικό θα περιλαμβάνεται και το ΑΓΓΛΙΚΟ-ΕΛΛΗΝΙΚΟ ΛΕΞΙΚΟ ΟΡΩΝ ΒΙΟΧΗΜΕΙΑΣ & ΜΟΡΙΑΚΗΣ ΒΙΟΛΟΓΙΑΣ της ΕΕΒΜΒ.

*** Selecting the Registration Supplement in the conference material will also include the English-Greek Dictionary of Biochemistry & Molecular Biology published by HSBMB.

Ακυρώσεις Οι εγγραφές δεν ακυρώνονται.

Cancellations Registrations are not canceled.

• Παρακολούθηση του επιστημονικού προγράμματος • Επίσκεψη στον εκθεσιακό χώρο • Τσάντα Συνεδρίου • Τελικό πρόγραμμα – Πρακτικά σε USB • Κονκάρδα • Πιστοποιητικό Παρακολούθησης • Καφέ στα διαλείμματα • Κοκτέιλ υποδοχής

• Conference Attendance • Access to the exhibition area • Conference bag • Final program - Proceedings on USB • Pin • Certificate of Attendance • Coffee Breaks • Welcome cocktail

• Παρακολούθηση του επιστημονικού προγράμματος • Επίσκεψη στον εκθεσιακό χώρο • Κονκάρδα • Συνοπτικό πρόγραμμα • Πιστοποιητικό παρακολούθησης

• Conference Attendance • Access to the exhibition area • Pin • Brief programme • Certificate of Attendance

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Πληροφορίες Επιστημονικού Προγράμματος

Information on the Scientific Program

Επιστημονικό Πρόγραμμα

Scientific Program

Το επιστημονικό πρόγραμμα του Συνεδρίου περιλαμβάνει 14 διαλέξεις Ελλήνων και ξένων προσκεκλημένων ομιλητών, 47 σύντομες προφορικές ανακοινώσεις οργανωμένες σε 8 συνεδρίες, 2 εταιρικές ομιλίες και 200 αναρτημένες ανακοινώσεις (πόστερ) που θα παρουσιαστούν σε δύο συνόδους.

The Scientific Program of the Conference includes 14 lectures by invited speakers, 47 short oral presentations (arranged in 8 sessions), 2 sponsored lectures and presentation of 200 posters arranged in two sessions.

Short Oral Presentations

The time slot for each Short Oral Presentation is 15 minutes (12 min for the presentation and 3 min for discussion). These time limits must be strictly respected by both presenters and chair persons in order to ensure the regular flow of the scientific program.

Σύντομες Προφορικές Ανακοινώσεις

Ο διαθέσιμος χρόνος για κάθε σύντομη προφορική παρουσίαση είναι 15 λεπτά (12 λεπτά χρόνος παρουσίασης και 3 λεπτά διαθέσιμα για ερωτήσεις και απαντήσεις). Τα χρονικά αυτά όρια πρέπει να τηρηθούν αυστηρά από τους ομιλητές και τα Προεδρεία για την ομαλή διεξαγωγή του επιστημονικού προγράμματος.

Technical Support

Invited speakers and oral presenters will need to hand their electronic presentation(s) to the technical support personnel at least one (1) hour prior to the relevant Session. If the presentation is scheduled for early in the morning, they are requested to check their presentation with the technical support personnel the previous day.

Τεχνική Υποστήριξη

Οι προσκεκλημένοι ομιλητές και οι εισηγητές των προφορικών ανακοινώσεων πρέπει να παραδώσουν την ηλεκτρονική τους παρουσίαση στην τεχνική γραμματεία του συνεδρίου τουλάχιστον 1 ώρα πριν την έναρξη της σχετικής συνεδρίας. Εάν η ομιλία είναι προγραμματισμένη για νωρίς το πρωί, η παρουσίαση πρέπει να παραδοθεί την προηγούμενη ημέρα.

Poster Sessions

The posters will be displayed according to the following program on appropriately numbered boards. The dimensions of each poster should be 80 cm wide and 120 cm (max) high.

Αναρτημένες Ανακοινώσεις (Πόστερ)

Τα πόστερ θα αναρτηθούν σύμφωνα με το παρακάτω πρόγραμμα σε κατάλληλα αριθμημένα πάνελ. Οι διαστάσεις των πόστερ πρέπει να είναι 0,80 m πλάτος και έως 1,20 m μέγιστο ύψος.

Posters P001-P100 will be on display from Friday, November 23, 08:30, to Saturday, November 24, 10:00 (Poster Session A). Authors will present odd-numbered posters (Ρ001-Ρ099) during Poster Session A-I (14:0015:00) while even-numbered posters (P002-P100) will be presented during Poster Session A-II (15:30-18:30).

Τα πόστερ P001-P100 θα αναρτηθούν από Παρασκευή, 23 Νοεμβρίου, 08:30, έως Σάββατο, 24 Νοεμβρίου, 10:00 (Σύνοδος Α). Οι συγγραφείς θα παρουσιάσουν τα πόστερ με μονό αριθμό (Ρ001-Ρ099) κατά τη διάρκεια της Συνόδου Α-Ι (14:00-15:00) ενώ τα πόστερ με ζυγό αριθμό (Ρ002-Ρ100) θα παρουσιαστούν κατά τη διάρκεια της Συνόδου Α-ΙΙ (17:30-18:30).

Posters P101-P200 will be on display from Saturday, November 24, 10:30, to Sunday, November 25, 12:00 (Poster Session B). Authors will present odd-numbered posters (Ρ101-Ρ199) during Poster Session B-I (14:0015:00) while even-numbered posters (P102-P200) will be presented during Poster Session B-II (15:30-18:30).

Τα πόστερ P101-P200 θα αναρτηθούν από Σάββατο, 24 Νοεμβρίου, 10:30, έως Κυριακή, 25 Νοεμβρίου, 12:00 (Σύνοδος Β). Οι συγγραφείς θα παρουσιάσουν τα πόστερ με μονό αριθμό (Ρ101-Ρ199) κατά τη διάρκεια της Συνόδου Β-Ι (14:00-15:00) ενώ τα πόστερ με ζυγό αριθμό (Ρ102-Ρ200) θα παρουσιαστούν κατά τη διάρκεια της Συνόδου B-ΙΙ (17:30-18:30).

Awards and Scholarships of the 69th Conference of the HSBMB

The HSBMB has announced awards and travel scholarships for young scientists, registered affiliated or full members of HSBMB, who will present their work in the 69th Conference of the HSBMB. The presented works will be judged for scientific excellence and presentation quality by committees of experienced scientists appointed by the Administrative Board of the HSBMB. The oral and poster presentation awards will be announced during the Closing Ceremony at the end of the Conference. Travel scholarships will also be announced during the Conference.

Βραβεία και Υποτροφίες 69ου Συνεδρίου EEBMB

Η ΕΕΒΜΒ έχει ανακοινώσει ότι στο πλαίσιο του 69ου Συνεδρίου της θα δοθούν βραβεία και έπαινοι για προφορικές και αναρτημένες ανακοινώσεις εργασιών σε νέους επιστήμονες που είναι ταμειακώς τακτοποιημένα αρωγά ή τακτικά μέλη της ΕΕΒΜΒ. Οι εργασίες θα κριθούν από επιτροπές έμπειρων επιστημόνων που θα οριστούν από το ΔΣ της ΕΕΒΜΒ, με κριτήρια την επιστημονική αριστεία και ποιότητα της παρουσίασης. Τα βραβεία θα ανακοινωθούν κατά την Τελετή Λήξης του Συνεδρίου. Οι υποτροφίες συμμετοχής της ΕΕΒΜΒ θα ανακοινωθούν κατά την διάρκεια του Συνεδρίου.

Certificate of Attendance

All registered participants are entitled to receive a Certificate of Attendance. The Certificates will be issued on Sunday, November 25th 2018, at the end of the Scientific Program.

Πιστοποιητικά παρακολούθησης

Όλοι οι εγγεγραμμένοι σύνεδροι δικαιούνται Πιστοποιητικό Παρακολούθησης. Τα πιστοποιητικά θα εκδοθούν την Κυριακή 25 Νοεμβρίου 2018, στο τέλος του Επιστημονικού Προγράμματος.

e-Abstract Book

Abstracts of all the Lectures, Oral Presentations and Poster Presentations are included in the e-Abstract Book of the Conference which will be delivered to all eligible registered participants.

Ηλεκτρονικός τόμος περιλήψεων

Οι περιλήψεις των ομιλιών και των προφορικών και αναρτημένων ανακοινώσεων περιλαμβάνονται σε ηλεκτρονικό τόμο (USB Stick) που λαμβάνουν οι σύνεδροι με πλήρη εγγραφή.

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Προσκεκλημένοι Ομιλητές | Invited Speakers

Iain Mattaj European Molecular Biology Laboratory, Heidelberg, Germamy

Anne Osbourn Norwich Research Park Industrial Biotechnology Alliance, John Innes Centre, Norwich Research Park, Norwich, United Kingdom

Peter Ratcliffe Target Discovery Institute, University of Oxford, United Kingdom

David Stuart Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, United Kingdom

Grigoris D. Amoutzias University of Thessaly, Larisa, Greece

George Christophides Imperial College London, United Kingdom

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Spyros Georgatos University of Ioannina, Greece

Othon Iliopoulos Harvard Medical School, Massachusetts General Hospital Cancer Center, Boston, United States

Katerina Katsani Democritus University of Thrace, Alexandroupoli, Greece

Antonis Koromilas McGill University, Montreal, Canada

Nikos Kyrpides DOE Joint Genome Institute, Berkley, United States

George Spyroulias University of Patras, Greece

Christos Tsatsanis University of Crete, Herakleion, Greece

Christos G. Zervas Biomedical Research Foundation, Academy of Athens, Center of Basic Research, Greece

www.eebmb-congress.gr

Επιστημονικό Πρόγραμμα | Scientific Program

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology November 23-25, 2018 Imperial Hotel, Larissa

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Friday, 23rd November 2018

Friday, 23rd November 2018 9:00-11:00 SESSION 1: Development & Signal Transduction Chairs: Eleni Georgatsou, Anna-Maria Psarra 9:00-9:15 O1. Mechanotransductive cascade of Myo-II-dependent mesoderm and endoderm invaginations in embryo gastrulation Démosthène Mitrossilis, Jens-Christian Röper, Damien Le Roy, Benjamin Driquez, Aude Michel, Christine Ménager, Gorky Shaw, Simon Le Denmat, Laurent Ranno, Frédéric Dumas-Bouchiat, Nora M. Dempsey & Emmanuel Farge* Institut Curie, 26 rue d’Ulm, 75248 Paris Cedex 05

9:15-9:30 O2. The tumor suppressor CYLD prevents epithelial to mesenchymal transition in mammary epithelial cells Athanasios Pseftogas1*, Konstantinos Xanthopoulos1, Theofilos Poutahidis2 Chrysanthi Ainali3, Dimitra Dafou1, Emmanuel Panteris1, Alexander Hardas2, Eudoxia Hatzivassiliou4 and George Mosialos1 School of Biology, 2School of Veterinary Medicine & 4School of Medicine, University of Thessaloniki; 3St John’s Institute of Dermatology, School of Basic and Medical Biosciences, London 1

9:30-9:45 O3. Elucidating the implication of the licensing factor Cdc6 in double strand break repair Andreas Panagopoulos1, Vassilis Roukos3, Stavros Taraviras2, Zoi Lygerou1*

Department of General Biology & 2Department of Physiology, School of Medicine, University of Patras; 3Institute of Molecular Biology (IMB), Mainz

9:45-10:00 O4. DNA damage induces nuclear translocation of SRPK1 Ioanna Sigala1, Maria Koutroumani1,2, Eleni Nikolakaki1, Thomas Giannakouros1*

Laboratory of Biochemistry, Department of Chemistry, University of Thessaloniki; 2Present address: Institute of Applied Biosiences, Centre for Research & Technology Hellas, Thermi 1

10:00-10:15 O5. Identification of determinants attributing Src Family Kinase substrate specificity Nikolaos Koutras, Dimitrios Konstantinou, Vasileios Morfos and Konstantina Nika Department of Biochemistry, School of Medicine, University of Patras

10:15-10:30 O6. Characterization of exosomes as novel drug delivery systems by multiparametric physicochemical analysis and molecular profiling Lefki-Pavlina Giassafaki1, Konstantina Psatha2, Scheyla Siqueira3, Konstantinos A. Kyritsis1, Anette Müllertz3, Eleni Pavlidou4, Michalis Aivaliotis2,5, Georgios Tzimagiorgis5, Dimitrios Fatouros6, Ioannis S. Vizirianakis1,*

Laboratory of Pharmacology, 4Department of Solid State Physics, 5Laboratory of Biochemistry, School of Medicine & 6Laboratory of Pharmaceutical Technology, University of Thessaloniki; 2Institute of Molecular Biology and Biotechnology (IMBB), Crete; 3Laboratory of Pharmaceutical Technology, University of Copenhagen 1

10:30-11:00 Plenary Lecture 1: Integrin-mediated adhesion in tissue morphogenesis Christos G. Zervas Biomedical Research Foundation Academy of Athens, Athens

11:00-11:30 Coffee Break

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Friday, 23rd November 2018

11:30-13:30 SESSION 2: Cell organization & function Chairs: Efrosyni Paraskeva, Georgia Chachami 11:30-11:45 O7. Evaluation of lumican effects in morphology of invading breast cancer cells, expression of integrins and downstream signaling Konstantina Karamanou1,2,3, Marco Franchi4, Maurizio Onisto5, Alberto Passi6, Demetrios H. Vynios1, Stéphane Brézillon2,3

Laboratory of Biochemistry, Department of Chemistry, University of Patras; 2Université de Reims Champagne Ardenne, Laboratoire de Biochimie Médicale et Biologie Moléculaire & 3CNRS UMR 7369, Matrice Extracellulaire et Dynamique Cellulaire, Reims; 4Department for Life Quality Studies, University of Bologna, Rimini; 5University of Padova, Department of Biomedical Sciences, Padova; 6Dipartimento di Scienze Chirurgiche e Morfologiche, Università degli Studi dell’Insubria, Varese 1

11:45-12:00 O8. Adherens Junctions in early cardiovascular progenitor cells Violetta A. Maltabe1,2, Ioulia Charizopoulou1 and Panos Kouklis1,2 * 1 2

Laboratory of Biology, Medical School, University of Ioannina & Department of Biomedical Research, Institute of Molecular Biology & Biotechnology, Foundation of Research and Technology-Hellas, Ioannina

12:00-12:15 O9. The presence of Argonautes in filopodial protrusions reveals their role in intercellular trafficking Vasiliki Pantazopoulou1, Stella Georgiou1, Vicky Filippa1, Stamatis Pagkakis1, Ismini Kloukina1, Andriana Aktypi1, Sofia Tseleni-Balafouta2, Dimitrios J. Stravopodis3, Ema Anastasiadou1*

1 Biomedical Research Foundation of the Academy of Athens (BRFAA); 2Department of Pathology, Medical School & 3Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens

12:15-12:30 O10. CHD4 is a novel partner of HURP during mitosis that regulates spindle assembly via formation of a mitotic complex with Aurora A and TPX2 Sotirios Galtsidis1, Konstantinos Nakos1,2, Ileana Kesisova1,2, Margy Koffa2*

Life Science Research Unit, University of Luxembourg; 2Department of Molecular Biology and Genetics, University of Thrace, Alexandroupolis

12:30-12:45 O11. Cdc6 directs a wave of MCM2-7 helicase loading onto chromatin in late G1, which is required for the firing of dormant origins Alexandra Kanellou1, Andreas Panagopoulos1, Ioanna-Eleni Symeonidou1,3, Stavros Taraviras2, Zoi Lygerou1*

Department of General Biology & 2Department of Physiology, School of Medicine, University of Patras; 3Current address: University Hospital, University of Zurich 1

12:45-13:00 O12. Evidence for nuclear translocation of the membrane androgen receptor, OXER1 Panagiotis Malamos1 *, Athanasios Panagiotopoulos1, Konstantina Kalyvianaki1, Hara Polioudaki2, Panayiotis Theodoropoulos2, George Notas1, Elias Castanas1, Marilena Kampa1 Laboratories of 1 Experimental Endocrinology & 2Biochemistry, School of Medicine, University of Crete

13:00-13:30 Plenary Lecture 2: Moonlighting at the nuclear pores: Unexpected structure and function patterns of outer coat nucleoporins Katerina Katsani Department of Molecular Biology & Genetics, University of Thrace, Alexandroupolis

13:30-14:00 Sponsored Lecture More from less the smart way- multiplex protein immunoassays using xMAP technology Dr Igor Pongrac MERCK, LIFE SCIENCES

14:00-15:00 Poster Session Α-Ι Presentation of odd-numbered posters P001-P099

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Friday, 23rd November 2018

15:00-17:00 SESSION 3: Systems Biology & Bioinformatics Chairs: Georgios Papadopoulos, Vassiliki Kostourou 15:00-15:30 Plenary Lecture 3: Microbiome Research: from Products to Data Nikos Kyrpides Joint Genome Institute, Berkley

15:30-15:45 O13. Comparative Analysis of the Human, Rat and Mouse Uniquomes Evangelos Kontopodis1, Vasileios Pierros1, Athanasios K. Anagnostopoulos1, Dimitrios J. Stravopodis2, Isidora S. Papassideri2, Constantinos E. Vorgias3 and George Th. Tsangaris1

Proteomics Research Unit, Biomedical Research Foundation of the Academy of Athens; 2Section of Cell Biology & Biophysics, Department of Biology & 3Section of Biochemistry & Molecular Biology, Department of Biology, University of Athens 1

15:45-16:00 O14. Comparative analysis of prokaryotic extracellular vesicle proteins and their targeting signals Ilias Stathatos, Vassiliki Lila Koumandou*

Department of Biotechnology, Agricultural University of Athens

16:00-16:15 O15. Molecular classification of Non – Muscle Invasive Bladder Cancer according to global protein expression Rafael Stroggilos1*, Manousos Makridakis1, Agnieszka Latosinska2, Vasiliki Lygirou1, Charalampos Fragkoulis3, William Mullen4, Harald Mischak2, Konstantinos Ntoumas3, Emmanouil Mavrogeorgis5, Dimitrios Drekolias6, Jeronymos Zoidakis1, Antonia Vlahou1

Biotechnology Division, Biomedical Research Foundation of the Academy of Athens; 2Mosaiques Diagnostics, Hannover; 3Department of Urology, Athens General Hospital ‘George Gennimatas’; 4British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow; 5Department of Biotechnology, Agricultural University of Athens; 6Department of Pathology, University of Athens 1

16:15-16:30 O16. Development of a CRISPR/Cas9 synthetic X-distortion system for the genetic control of the olive fruit fly, Βactrocera oleae Konstantina Tsoumani1*, Philippos A. Papathanos2, Νikolai Windbichler3 and Kostas Mathiopoulos1

Laboratory of Molecular Biology and Genomics, Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 2Department of Entomology, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem; 3Department of Life Sciences, Imperial College London 1

16:30-16:45 O17. Lymphocytic and synaptic pathways associated with Tourette Syndrome Fotis Tsetsos1, Stavroula Topali1, Margaritis Tsifintaris1, Alexis Galanis1, Peristera Paschou2* 1

Department of Molecular Biology and Genetics, University of Thrace, Alexandroupolis; 2Department of Biological Sciences, Purdue University

16:45-17:00 O18. Conformational sampling and dual targeting of the GHRHR Minos-Timotheos Matsoukas1*, Robin du Preez2, Alex Fish3, Claire Newton2, Ross Anderson2, Patrick Celie3, Anastassis Perrakis3, Robert Millar2, Georgios A. Spyroulias1 Department of Pharmacy, University of Patras; 2Centre for Neuroendocrinology, Faculty of Health Sciences, University of Pretoria; 3Department of Biochemistry, The Netherlands Cancer Institute, Amsterdam 1

17:00-17:30 Coffee Break 17:30-18:30 Poster Session Α-ΙI Presentation of even-numbered posters P2-P100

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Friday, 23rd November 2018

18:30-20:30 Opening Ceremony & KEYNOTE Lectures Chairs: Nikos K. Karamanos, George Simos, Demetres D. Leonidas 18:30-19:00 Welcome Addresses 19:00-19:45 Keynote Lecture 1: Elucidation of Cellular Oxygen Sensing Pathways: Implications for Biology Sir Peter Ratcliffe, FRS Nuffield Department of Medicine, University of Oxford

19:45-20:30 Keynote Lecture 2: Virus Structure in vitro and in the cell: Implications for biology and therapy David Stuart, FRS Division of Structural Biology, University of Oxford

20:30-21:30 Welcome cocktail and Buffet

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Saturday, 24th November 2018

Saturday, 24th November 2018 9:00-11:00 SESSION 4: Molecular & Cellular Basis of Human Disease I Chairs: George Mosialos, Ilias Mylonis 9:00-9:15 O19. Apolipoprotein E (apoE) isoforms and carboxyl-terminal truncated apoE4 forms influence neuronal amyloid-beta peptide (Aβ) production Ioannis Dafnis1, Christina Raftopoulou1, Christina Mountaki1, Evgenia Megalou1, Vassilis I. Zannis2 and Angeliki Chroni1* Institute of Biosciences and Applications, National Center for Scientific Research “Demokritos”, Agia Paraskevi-Athens; 2Departments of Medicine & Biochemistry, Molecular Genetics, Whitaker Cardiovascular Institute, Boston University School of Medicine 1

9:15-9:30 O20. The transcriptional networks of Alcoholic Liver Disease (ALD) Stella Georgiou1, Vicky Filippa1, Maria Lala1, Vasiliki Pantazopoulou1, GALAXY consortium2, Ema Anastasiadou1* Biomedical Research Foundation, Academy of Athens

9:30-9:45 O21. Evidence for antigen selection in the aggressive chronic lymphocytic leukemia subset #2 using state-of-the-art NGS methodologies Katerina Gemenetzi1,2, Andreas Agathangelidis1, Lesley-Ann Sutton3, Elisavet Vlachonikola1,4, Chrysi Galigalidou1,2, Fotis Psomopoulos1, Maria Gounari1, Achilles Anagnostopoulos5, Raphael Sandaltzopoulos2, Richard Rosenquist3, Kostas Stamatopoulos1, Anastasia Hadzidimitriou1,3*

Institute of Applied Biosciences (INAB), Centre for Research and Technology Hellas, Thessaloniki; 2Dept. of Molecular Biology and Genetics (MBG), University of Thrace, Alexandroupolis; 3Karolinska Institute, Stockholm; 4Department of Genetics, Development and Molecular Biology, University of Thessaloniki; 5 Hematology Department & HCT Unit, G. Papanikolaou Hospital, Thessaloniki 1

9:45-10:00 O22. Targeting mitochondria to treat brain dysfunction: A bioenergetics perspective Michaela D. Filiou1*

Department of Biological Applications and Technology, University of Ioannina

10:00-10:15 O23. Development of in vitro transcribed SCO2 mRNA as novel therapeutic approach in a mitochondrial disorder, due to SCO2 mutations Androulla N. Miliotou1, Ioannis S. Pappas2, Ioannis S. Vizirianakis1, Lefkothea C. Papadopoulou1*

Laboratory of Pharmacology, School of Pharmacy, University of Thessaloniki; 2Laboratory of Pharmacology and Toxicology, Faculty of Veterinary Science, University of Thessaly 1

10:15-10:30 O24. A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction Maro Iliopoulou1, Rory Nolan1, Luis Alvarez1, Yasunori Watanabe2,3,4, Charles Coomer1, Maria Jakobsdottir1, Thomas A. Bowden2 and Sergi Padilla Parra1,2,5,6 *

Cellular Imaging Core & 2Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford; 3Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford; 4Centre for Biological Sciences and Institute of Life Sciences, University of Southampton; 5Dynamic Structural Virology Group, Biocruces Health Research Institute, Barakaldo; 6Ikerbasque, Basque Foundation for Science, Bilbao 1

10:30-11:00 Plenary Lecture 4: The Integrated Stress Response and its Connection to Cancer Antonis Koromilas Lady Davis Institute, Department of Oncology, Faculty of Medicine, McGill University

11:00-11:30 Coffee Break

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Saturday, 24th November 2018

11:30-13:30 SESSION 5: Molecular & Cellular Basis of Human Disease II – Focus on Cancer Chairs: Dionyssios Sgouras, Panagiotis Liakos 11:30-11:45 O25. Geminin ablation and Cdt1 overexpression in vivo enhance tumorigenesis Spyridon Champeris Tsaniras1, Michalis Petropoulos2, Iosif Rodolfos Danalatos1, Maria Villiou1*, Anastassios D Giannou3*, Sofia Nikou4, Ioannis S Pateras5, Paraskevi Tserou1, Foteini Karousi1, MariaEleni Lalioti1, Vassilis G. Gorgoulis5-7, Alexandra L Patmanidi1, George Stathopoulos3, Vasiliki Bravou4, Zoi Lygerou2 & Stavros Taraviras1

Department of Physiology, 2Department of Biology, 3Laboratory for Molecular Respiratory Carcinogenesis, 4Department of Anatomy-Histology-Embryology, Medical School, University of Patras; 5Department of Histology and Embryology, School of Medicine, University of Athens; 6Biomedical Research Foundation of the Academy of Athens; 7Faculty of Biology, Medicine and Health, University of Manchester; *Equal contribution 1

11:45-12:00 O26. High mRNA expression of the molecular chaperone Clusterin (CLU) and heatshock protein beta-3 (HSPB3) is associated with colorectal cancer recurrence Maria-Anna Kalioraki1*, Aikaterini-Anna Liosi1*, Aimilia D. Sklirou2, Maria-Christina Cheimonidi2, Christos K. Kontos1, Andreas Scorilas1, Ioannis P. Trougakos2 1

Department of Biochemistry & 2Department of Cell Biology, Biophysics and Molecular Biology, Faculty of Biology, University of Athens; *Equal contributors

12:00-12:15 O27. Identification of the mechanism underlying the miR-520f-mediated sensitization of tumor cells to chemotherapeutic drugs Konstantina Nikolakopoulou1, Mirjam de Weijert1, Kees Jansen1, Onno van Hooij1, Iman Schultz2, Roel Schaapveld2, Jack Schalken1, Gerald Verhaegh1*

Department of Urology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen; 2InteRNA Technologies BV, Utrecht, the Netherlands. 1

12:15-12:30 O28. Mutational profile and cellular origins of primary skin mucinous carcinomas Anastasios D. Papanastasiou*,1, Pier Selenica2, Chaido Sirinian1, Britta Weigelt2, Haralabos P. Kalofonos1, Jorge S. Reis-Filho2

Molecular Oncology Laboratory, Department of Medicine, University of Patras; 2Department of Pathology, Memorial Sloan Kettering Cancer Center, New York

12:30-12:45 O29. Epigenetic drugs as a new therapeutical approach for targeting the breast Cancer Stem Cells John Verigos1,2, +, Panos Karakaidos2,3, +, Dimitris Kordias1,2, Apostolos Klinakis3 and Angeliki Magklara1,2* Laboratory of Clinical Chemistry, Faculty of Medicine, University of Ioannina; 2Department of Biomedical Research, Institute of Molecular Biology & Biotechnology, Foundation for Research & Technology-Hellas, Ioannina; 3Biomedical Research Foundation Academy of Athens; +equal contribution 1

12:45-13:00 O30. Serglycin instigates the aggressive phenotype of glioblastoma cells Dimitra Manou1, Panagiotis Bouris1, Dimitris Kletsas2, Nikos K. Karamanos1, Achilleas Theocharis1* 1 2

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras; Laboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR “Demokritos”, Athens

13:00-13:30 Plenary Lecture 5: Identification and validation of therapeutic targets in tumor hypoxia and metabolic reprogramming Othon Iliopoulos Massachusetts General Hospital Cancer Center & Harvard Medical School

13:30-14:00 Sponsored Lecture Complete and Smart solution to qualify sample in microscopy Mélanie Merceur BERTIN TECHNOLOGIES

14:00-15:00 Poster Session B-Ι Presentation of odd-numbered posters P101-P199 15

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Saturday, 24th November 2018

14:00-15:00 General Assembly of HSBMB 15:00-17:00 SESSION 6: Gene Expression & RNA Biology Chairs: Dimitris Kardassis, Nikos Balatsos 15:00-15:30 Plenary Lecture 6: Metabolic and epigenetic regulation of innate immunity under the control of Akt kinases Christos Tsatsanis Clinical Chemistry Laboratory, Medical School, University of Crete

15:30-15:45 O31. Liver-specific ablation of HNF-4α in mice is associated with changes in plasma lipoprotein profiles and the expression of genes involved in glucose and lipoprotein metabolism Efstathia Thymiakou1,2, Dimitris Kardassis1,2 *

University of Crete Medical School & 2Institute of Molecular Biology and Biotechnology, Gene Regulation and Epigenetics, Heraklion

15:45-16:00 O32. Aldehyde dehydrogenase 3A1 (ALDH3A1) is involved in the DNA damage response pathways in human corneal epithelial cells Georgia-Persephoni Voulgaridou1, Ilias Tsochantaridis1, Michael I. Koukourakis2, Alexandra Giatromanolaki3, Mihalis I. Panayiotidis4, Aglaia Pappa1*

Department of Molecular Biology & Genetics, 2Department of Radiotherapy/Oncology & 3Department of Pathology, University of Thrace, Alexandroupolis; Department of Applied Sciences, Northumbria University, Newcastle Upon Tyne

1 4

16:00-16:15 O33. Productive binding of hypoxia inducible factor-1α to chromatin requires its phosphorylation-dependent interaction with NPM1 Kreon Koukoulas1, Antonis Giakountis2, George Simos1*, Ilias Mylonis1*

Laboratory of Biochemistry, Faculty of Medicine & 2Laboratory of Molecular Biology and Genomics, Department of Biochemistry & Biotechnology, University of Thessaly, Larissa 1

16:15-16:30 O34. Selective regulation of inflammatory responses by myeloid restricted AUF1 Niki Lourou1, Sofia Gargani1, Fotis Ioakeimidis1, Maria-Ioanna Saridaki1, Vasileios Ntafis1, Aris Economides3, Dimitris L. Kontoyiannis1,2 * 1 2

Biomedical Sciences Research Center “Alexander Fleming”, Vari; School of Biology, University of Thessaloniki; 3Regeneron Inc., Tarrytown, New York

16:30-16:45 O35. Mutational analysis of staphylococcal-specific glyS T-box domains reveals species-specific modulation of transcription Nikoleta Giarimoglou1#, Vassiliki Stamatopoulou1#, Shuang Li2, Maria Apostolidi3, Eleni Kaliatsi1, Jinwei Zhang2 and Constantinos Stathopoulos1* Department of Biochemistry, School of Medicine, University of Patras; Laboratory of Molecular Biology, NIDDK, NIH, Bethesda; 3Department of Molecular and Cellular Physiology, School of Medicine, Yale Univeristy; #equal contribution 1 2

16:45-17:00 O36. GMO-free RNAi in plants. Athanasios Dalakouras1,2, Elena Dadami1 and Kalliope K. Papadopoulou1 1

Department of Biochemistry & Biotechnology, University of Thessaly, Larissa; 2Institute of Plant Breeding and Genetic Resources ELGO-DEMETER, Thessaloniki

17:00-17:30 Coffee Break 17:30-18:30 Poster Session B-ΙI Presentation of even-numbered posters P102-P200

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Saturday, 24th November 2018

18:30-20:30 SPECIAL SESSION: “Honouring the memory of Prof. Fotis Kafatos” (Sponsored by EMBL & EMBL Alumni Association) Chairs: Nikos K. Karamanos, Kostas Mathiopoulos, George Simos 18:30-19:00 Building a pan-European Legacy Iain Mattaj EMBL, Heidelberg

19:00-19:45 Haspin kinase: the Schrödinger’s cat? Spyros Georgatos Laboratory of Biology, Medical School, University of Ioannina

19:45-20:30 Mosquito innate immunity and malaria transmission blocking George Christophides Faculty of Natural Sciences, Imperial College London

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Sunday, 25th November 2018

Sunday, 25th November 2018 9:00-11:00 SESSION 7: Structure & Function of Macromolecules Chairs: Dimitris Kletsas, Vassiliki T. Skamnaki 9:00-9:15 O37. High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. Anthony Bougas2, Maxim S. Svetlov1, Elena Plessa2, Eleni Poulou2, Marios Krokidis2, George P. Dinos2, Yury S. Polikanov3,4

Center for Biomolecular Sciences, 3Department of Biological Sciences, 4Department of Medicinal Chemistry, University of Illinois at Chicago; 2Department of Biochemistry, School of Medicine, University of Patras

9:15-9:30 O38. Affinity crystallography: a promising time-saving approach to determine the complete 3D structures of high-affinity, but low abundance drug target ligands. George A. Stravodimos, Efthimios Kyriakis, Theodora G.A. Solovou, Olga S. E. Papaioannou, Vassiliki T. Skamnaki and Demetres D. Leonidas* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa

9:30-9:45 O39. Structural analysis of the protein SAS-6 reveals the molecular mechanisms of centriolar cartwheel assembly Anastasia L. Kantsadi, Ioannis Vakonakis Department of Biochemistry, University of Oxford

9:45-10:00 O40. Humidity Induced Structural Changes on Hen Egg White Lysozyme (HEWL) polycrystalline precipitates Alexandros Valmas1*, Maria Spiliopoulou1, Souzana Logotheti1, Sofia Trampari2, Paraskevi Kontou1, Stavroula Fili1, Andrew N. Fitch3, Detlef Beckers4, Thomas Degen4, Gwilherm Nénert4, Fotini Karavassili1, Irene Margiolaki1 Department of Biology, University of Patras; 2Department of Physics, University of Athens; 3European Synchrotron Radiation Facility, Grenoble; 4Malvern Panalytical B.V., Almelo 1

10:00-10:15 O41. Structural insights into α-conotoxin RgIA binding to nicotinic α9α10 receptors Marios Zouridakis1*, Athanasios Papakyriakou2, Elena V. Kryukova3, Victor Tsetlin3, Igor E. Kasheverov3, Socrates Tzartos1 and Petros Giastas1,2* Department of Neurobiology, Hellenic Pasteur Institute; 2NCSR Demokritos, Athens; 3Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow

10:15-10:30 O42. The crystal structure of Anopheles gambiae OBP5 and a tale of two “temperaments” Panagiota G.V. Liggri1,2, Katerina E. Tsitsanou1, Francesca Saitta3, Christina E. Drakou1, Kostas Iatrou4, Dimitrios Fessas3, Spyros E. Zographos1*

Institute of Biology, Medicinal Chemistry and Biotecnhology, National Hellenic Research Foundation, Athens; 2Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 3Department of Food, Environmental and Nutritional Sciences (DeFENS) Università degli Studi di Milano; 4Insect Molecular Genetics and Biotechnology Group, Institute of Biosciences & Applications, National Centre for Scientific Research “Demokritos”, Athens 1

10:30-11:00 Plenary Lecture 7 (dedicated to the memory of Prof. D. Kalpaxis): The structural and dynamic basis for the function of biological molecules through solution NMR spectroscopy Georgios A. Spyroulias Department of Pharmacy, University of Patras

11:00-11:30 Coffee Break www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Sunday, 25th November 2018

11:30-12:15 Chairs: Andreas Tsakalof, Kalliope Papadopoulou Keynote Lecture 3: Harnessing plant metabolic diversity Anne Osbourn John Innes Centre, Norwich

12:15-14:00 SESSION 8: Biotechnology Chairs: Andreas Tsakalof, Kalliope K. Papadopoulou 12:15-12:30 O43. Ancestral reconstruction approach to analyze the structure function and specificity relationships in the NAT/NCS2 family Ekaterini Tatsaki, Stathis Frillingos*

Laboratory of Biological Chemistry, Department of Medicine, University of Ioannina

12:30-12:45 O44. Deciphering the structure, nucleotide and RNA binding selectivity of viral macro domains Aikaterini C. Tsika1, Efstathios Melekis1, Sofia-Antigoni Tsatsouli1, Nicolas Papageorgiou2, Maria J. Maté2, Bruno Canard2, Bruno Coutard2*, Detlef Bentrop3, Georgios A. Spyroulias1* Department of Pharmacy, University of Patras; 2AFMB, UMR7257 CNRS/Aix Marseille Université; 3Institute of Physiology II, Faculty of Medicine, University of Freiburg 1

12:45-13:00 O45. A mobile microRNA acts as a systemic mediator of legume susceptibility to rhizobial infection Daniela Tsikou1, Zhe Yan1, Dennis B. Holt1, Nikolaj B. Abel1, Dugald E. Reid1, Lene H. Madsen1, Moritz Sexauer2, Hemal Bhasin2, Jens Stougaard1, Katharina Markmann1,2 1

Aarhus University, Denmark; 2Tübingen University, Germany

13:00-13:15 O46. Virus-Induced Gene Silencing as a versatile tool for functional genomics in Oleaceae Margarita Thomopoulou1*, Konstantinos Koudounas2, Georgios Papakostas1, Polydefkis Hatzopoulos1 1

Agricultural University of Athens, Department of Biotechnology, Molecular Biology Lab; 2University of Tours, Biomolecules and Plant Biotechnologies Lab

13:15-13:30 O47. “Omics” providing evidence on the presence of a catechol and gentisate pathway in the biodegradation of aromatic compounds by Pseudarthrobacter phenanthrenivorans Sphe3 Chris Fanitsios1, Matina Asimakoula1, Elpiniki Vandera1, Epaminondas Tsagogiannis1, Athanassios Karkabounas1and Anna Irini Koukkou1* Sector of Organic Chemistry and Biochemistry, University of Ioannina

13:30-14:00 Plenary Lecture 8: Post-translational modifications in the era of Proteomics and Bioinformatics Grigoris D. Amoutzias Department of Biochemistry & Biotechnology, University of Thessaly, Larissa

14:00-14:30 Closing Ceremony – Prize Awards

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Ιοφώντος 1 Αθήνα T.K 116 34 Τηλ:(+30) 210 72 94 603 Fax: (+30) 210 72 94 606 e-mail: info@labsupplies.gr

Αναρτημένες Ανακοινώσεις | Poster Sessions

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology November 23-25, 2018 Imperial Hotel, Larissa

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

SESSION A – FRIDAY 23rd November 2018 01. Stem Cells and Tissue Regeneration P001-P010 P001 Efficient generation of neuroprogenitors from cord blood-derived very small embryoniclike stem cells for the treatment of inner retinal injuries Eleni Gounari1,3*, Aggelos Daniilidis2, Vasileios Karampatakis3, George Koliakos1,3

Biohellenika Biotechnology Company, 57001, Thessaloniki; 2University Clinic of Obstetrics and Gynecology, Hippokration General Hospital, Thessaloniki; 3Medical School, University of Thessaloniki 1

P002 Design of a low-cost open-source bioprinter for 3D cell culture Konstantinos Ioannidis1*, Iosif Rodolfos Danalatos1, Spyridon Champeris Tsaniras1, Zoi Lygerou2, Stavros Taraviras1 1

Department of Physiology & 2Department of Biology, Medical School, University of Patras

P003 Expression of stem cell factors in monocyte-derived multipotential cells (MOMCs) easily isolated from leukapheresis filters Maria Karakota, Eleni Gounari, George Karolidis, Nikolaos Papanikolaou, George Koliakos Laboratory of Biological Chemistry, Medical School, University of Thessaloniki

P004 ABSTRACT WITHDRAWN P005 On the way to produce self-assembling “recombinamer” proteins with the aim to fabricate 3D scaffolds for tissue engineering purposes Paraskevas Lamprou1*, Aglaia Mantsou1, Theodora Choli-Papadopoulou1 1

Laboratory of Biochemistry, School of Chemistry, University of Thessaloniki

P006 Mural cells of Distinct Phenotypes Differentiated from Human Pluripotent Stem Cells: Generation of 3D Vascular Units for Tissue Engineering. Markou Maria1,2, Bagli E1,3, Kouroupis D1, Kyrkou Athena1, Badounas F4, Kostopoulou N1, Murphy Carol1 Fotsis T1,2

Division of Biomedical Research, Institute of Molecular Biology and Biotechnology - FORTH, Ioannina; 2Laboratory of Biological Chemistry, Medical School, University of Ioannina; 3Department of Ophthalmology, University of Ioannina; 4Department of Immunology, Inflammation Group, Transgenic Technology Laboratory, Hellenic Pasteur Institute 1

P007 The role of Geminin in licensing of DNA replication during early and mid corticogenesis Maria Mougkogianni1*, Argyro Kalogeropoulou1, Marianna Iliadou1, Zoi Lygerou2, Stavros Taraviras1 1

Department of Physiology & 2Department of General Biology, School of Medicine, Patras University

P008 Association of a C-terminal peptide of Transforming Growth Factor β1 with chondrogenesis and potent use as a therapeutic agent in osteoarthritis Maria Pitou1*, Stylianos Zafeirios Karoulias1, Theodora Choli-Papadopoulou1 1

Department of Chemistry, University of Thessaloniki

P009 Responses of human skin fibroblasts to thymosinic peptides related to wound repair Harris Pratsinis1, Lena Kikidou1,2, Stefania Grammatikaki2, Anna Santorinaiou1, Evangelia Livaniou2, Dimitris Kletsas1* 1

Institute of Biosciences & Applications & 2Institute of Nuclear & Radiological Sciences and Technology, Energy & Safety, NCSR Demokritos

P010 On the synthesis and structural characterization of elastin-like recombinamer hydrogel scaffolds for tissue regeneration Ioannis Riziotis1, Paraskevas Lamprou1, Aglaia Mantsou1, Theodora Choli-Papadopoulou1* 1

Laboratory of Biochemistry, School of Chemistry, University of Thessaloniki

02. Growth, Differentiation and Aging P011-P014 P011 Spindle assembly checkpoint function alterations are implicated in the establishment of senescence of human mesenchymal stem cells Andreas Goutas, Evangelia Nikolopoulou, Arretha Telligiannidou, Varvara Trachana* Laboratory of Biology, Faculty of Medicine, University of Thessaly, Larissa

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P012 Integrin-Linked Kinase (ILK) tunes epithelial contractility and influence Drosophila egg chamber morphogenesis Athina Keramidiotou1,2, Eleni Psarra1, Elisavet Lotsi1, Christos G. Zervas1 1

Biomedical Research Foundation Academy of Athens; 2University of Thessaly, Department of Biochemistry, Larissa

P013 Development of an assay system for the evaluation of senolytic and senomorphic compounds in intervertebral disc cells Anastasios Kouroumalis1, Eleni Mavrogonatou1, Harris Pratsinis1, Olga D. Savvidou2, Panayiotis J. Papagelopoulos2, Dimitris Kletsas1*

Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research “Demokritos”, Athens; 2Attikon University General Hospital & Department of Orthopedics, Athens University Medical School 1

P014 Genetic crosstalk of mitochondrial LON protease and effectors of UPRmt in Caenorhabditis elegans Eirini Taouktsi1,2*, Eleni Kyriakou1*, Efstathios Trigazis1,2, Fivos Borbolis1 Stamatis Rigas2, Popi Syntichaki1 1

Biomedical Research Foundation of the Academy of Athens; 2Agricultural University of Athens

03. Cellular Communication and Signaling P015-P032 P015 Flavonoid quercetin affects matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in chondrocytes from articular cartilage of patients with osteoarthritis Aliki-Ioanna Apostolou*, Maria-Elpida Christopoulou, Zoi Kordou, Alexios Aletras Laboratory of Biochemistry, Department of Chemistry, University of Patras

P016 Effect of flavonoid quercetin on matrix metalloproteinases and their tissue inhibitors and on cytokines expression in synovial membrane fibroblasts of patients with osteoarthritis Aliki-Ioanna Apostolou*, Maria-Elpida Christopoulou, Maria Karamani, Alexios Aletras Laboratory of Biochemistry, Department of Chemistry, University of Patras

P017 Wisp-1 is implicated in osteoarthritis by enhancing the expression of MIF in human synovial fibroblasts Maria-Elpida Christopoulou*, Konstantina Xylia, Aliki-Ioanna Apostolou, Alexios Aletras Laboratory of Biochemistry, Department of Chemistry, University of Patras

P018 Anaplastic Lymphoma Kinase plays a role in Angiogenesis Despoina Ntenekou, Efrossyni Choleva, Pinelopi Kastana, Evangelia Papadimitriou Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras

P019 Timing and dynamics of recruitment of RabGTPases on Weibel Palade Bodies during regulated exocytosis in endothelial cells Despoina Gkeka1,2, Yannis Kalaidzidis3, Savvas Christoforidis1,2,* 1 2

Foundation for Research and Technology-Hellas (FORTH), Institute of Molecular Biology and Biotechnology (IMBB), Department of Biomedical Research, Ioannina; Laboratory of Biological Chemistry, Department of Medicine, University of Ioannina; 3Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.

P020 ERK1/2-dependent phosphorylation of HIF-2α regulates its activity by controlling its CRM1-mediated nuclear export Ioanna-Maria Gkotinakou, Christina Befani, Aikaterini Diseri, George Simos, Panagiotis Liakos* Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa

P021 Unconventional secretion in endothelial cells: Cytoplasmic galectin-1 enters WeibelPalade bodies Evangeli Goula1,2, Vasiliki Lazani1,2, Michalis Aivaliotis3,4, Savvas Christoforidis1,2,*

Foundation for Research and Technology-Hellas (FORTH), Institute of Molecular Biology and Biotechnology (IMBB), Department of Biomedical Research, Ioannina; Laboratory of Biological Chemistry, Department of Medicine, University of Ioannina; 3Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion; 4Department of Biochemistry, School of Medicine, AUTh, Thesaloniki 1 2

P022 Potential dissociative glucocorticoid receptor activity for extracts from resin and leaves of Chios Mastiha tree Foteini D. Kalousi1, Aikaterini G. Karra1, Giovanni Appendino2, Anna-Maria Psarra1* 1 2

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa Faculty of Pharmacy, University of Eastern Piedmont, Novara Italy

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P023 Lack of GemC1/Lynkeas increases the number of neural stem cells and leads to hydrocephalus Konstantina Kaplani1, Maria-Eleni Lalioti1, Christina Kyrousi1, Marina Arbi2, Georgia Lokka1, Evangelia Parlapani1, Zoi Lygerou2, Stavros Taraviras1 1

Department of Physiology & 2Department of General Biology, Medical School, University of Patras

P024 Development and validation of specific inhibitors against the PI3Kα E545K oncogenic mutant Valia Karamani1,2, Alexandra Papafotika1,2, George Markopoulos1,3, Evangelos Kolettas1,3, Hari Leontiadou4, Zoe Cournia4, Savvas Christoforidis1,2,*

Institute of Molecular Biology & Biotecnology, Department of Biomedical Research, Foundation for Research and Technology (IMBB-BR/FORTH), Ioannina; 2Labaratory of Biological Chemistry & 3Laboratory of Biology, Department of Medicine, University of Ioannina; 4Biomedical Research Foundation, Academy of Athens 1

P025 Potential dissociative glucocorticoid receptor activity for protopanaxadiol and protopanaxatriol Aikaterini G. Karra1, Maria Konstantinou1, Maria Tzortziou1, Ioannis Tsialtas1, Foteini D. Kalousi1, Joseph M. Hayes2, Constantine Garagounis1, Anna-Maria Psarra1,* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 2School of Physical Sciences & Computing, Division of Chemistry, University of Central Lancashire 1

P026 The Role of ARF6 in TGF-β family signaling in differentiated and human Embryonic Stem Cells Angelos Papadopoulos1, Nikoleta Kostopoulou*2, Sofia Bellou2, Eleni Bagli2, Maria Markou2, Athena Kyrkou2, Panayiota Chira2, Eleni Tschari3, Philippe Chavrier4, Theodore Fotsis2,4, Carol Murphy2

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham; 2Foundation of Research and Technology-Hellas, Institute of Molecular Biology & Biotechnology – Department of Biomedical Research, Ioannina; 3Centre de Recherche, Institut Curie, CNRS, UMR 144, Paris Cedex 05; 4Laboratory of Biological Chemistry, Medical School, University of Ioannina 1

P027 The extended activation of the JNK-Akt-Nrf2 pathway by the ATM-p53 pathway protects fibroblasts from UVB-mediated cytotoxicity Maria Angelopoulou1, Eleni Mavrogonatou1, Harris Pratsinis1, Sophia Rizou2, Vassilis G. Gorgoulis2, Dimitris Kletsas1*

Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research “Demokritos”; 2Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, University of Athens 1

P028 Investigation of the role of the tumor suppressor CYLD in HSV-1 infection Vasileios- Rafail Ouzounidis1, Demetrios N. Karatzas1, Sotirios G. Ntallis2, Konstantinos D. Gerakoudis2, Christos A. Panagiotidis2, George Mosialos1, Eudoxia G. Hatzivassiliou3 School of Biology, 2School of Pharmacy, 3School of Medicine, University of Thessaloniki

P029 Wisp-1 enhances MIF expression in N-Human Lung Fibroblasts Maria-Elpida Christopoulou*, Vassiliki Palaiologou, Aliki-Ioanna Apostolou, Alexios Aletras Laboratory of Biochemistry, Department of Chemistry, University of Patras

P030 Hyaluronan mediated effects on mammary cancer depends on its molecular size A.G. Tavianatou1, C. Barbera2, R. Beninatto2, A. Karaboga1, M. Franchi3, D. Galesso2, N.K. Karamanos1

Biochemistry, Biochem. Anal. & Matrix Pathobiology Res. Group, Dept. of Chemistry, University of Patras; 2Fidia Farmaceutici S.p.A., Abano Terme (PD), Italy; 3Human Anatomy Institute of the Department of Human Anatomical Sciences, University of Bologna 1

P031 Direct involvement of estrogen receptor beta in the regulation of mitochondrial transcription Ioannis Tsialtas1, Achilleas Georgantopoulos1, Vyron Gorgogietas1, Martina Samiotaki2, George Panayotou2, AnnaMaria Psarra1* 1

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 2Biomedical Sciences Research Center “Alexander Fleming”

P032 Statins differentially regulate cell surface receptors, EMT markers and extracellular components in breast cancer cells Stella Vasileiou, Dimitrios Lampadas, Meropi Glarou, Demitrios H. Vynios*

Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group, Department of Chemistry, University of Patras

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

04. Cellular Organization and Function P033-P058 P033 McIdas, a member of Geminin family proteins, maintains correct centriole numbers in cells Marina Arbi1, Vassiliki Petroulaki1, Sihem Zitouni2, Margarita Skamnelou1, Monica Bettencourt-Dias2, Stavros Taraviras3, Zoi Lygerou1* 1

Department of General Biology & 3Department of Physiology, School of Medicine, University of Patras; 2Instituto Gulbenkian de Ciência, Oeiras, Portugal

P034 Evidence for L-Dopa decarboxylase involvement in apoptosis Dimitrios Arvanitis1, Anastasia Tsakou1, Evangelos Kalantzis1, Ioanna Chalatsa1, Alice-Georgia Vassiliou2, Nikolaos Arvanitis1, Dido Vassilacopoulou1* Department of Biochemistry and Molecular Biology & 2Department of Critical Care Medicine & Pulmonary Services, GP Livanos and M Simou Laboratories, Evangelismos Hospital, Medical School, University of Athens 1

P035 Mapping the HURP interaction partners in time and space, during cell division Stelios Didaskalou1, Christos Efstathiou1, Ilona Kesisova1, Margy Koffa1* 1

Department of Molecular Biology and Genetics, Alexandroupolis

P036 ArcLight: a fluorescent protein voltage indicator expressed in HEK293 cells Anna Dimitriadi1,2*, Athanasios I. Papadopoulos1, Eudoxia G. Hatzivassiliou3, Efstratios Kosmidis2 1

Lab. of Animal Physiology, School of Biology & 2Lab. of Physiology, Department of Medicine, & 3Lab. Of Biochemistry, Department of Medicine, University of Thessaloniki

P037 Evidence for the TonB and Tol-Pal energy transduction systems in the thermophilic bacterium Thermus thermophilus HB8 Veronica Giourieva, Rigini Papi, Anastasia Pantazaki* University of Thessaloniki

P038 A comparative study of the membrane androgen receptors OXER1, GPRC6A and ZIP9 Konstantina Kalyvianaki1*, Panagiotis Malamos1, Athanasios Panagiotopoulos1, Eleni Moustou2, Maria Tzardi2, Efstathios N. Stathopoulos2, George Notas1, Elias Castanas1, Marilena Kampa1 Laboratory of Experimental Endocrinology & 2Department of Pathology, School of Medicine, University of Crete

P039 DNA re-replication elicits increased genetic instability at the ribosomal genes and aberrant nucleolar structures in fission yeast Eirini Kasselimi1, Stavros Taraviras2, Zoi Lygerou1*

Laboratory of General Biology & 2Laboratory of Physiology, School of Medicine, University of Patras

P040 Study of lymphoma cell lines after Nutlin-3a induced wild type (wt) p53-activation by Raman spectroscopy Klytaimnistra Katsara1,2, Konstantina Psatha2, Elias Drakos3, Vassilis Papadakis2, Michalis Aivaliotis2,4 *

Department of Chemistry & 3School of Medicine, University of Crete; 2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion; 4Laboratory of Biochemistry, School of Medicine, University of Thessaloniki 1

P041 ERs/EGFR axis as regulator of the functional cell properties, ECM remodeling and stemness in mammary cancer Konstantina Kyriakopoulou1*, Elena Kefali1,3,4, Zoi Piperigkou1,2, Martin Goette3, Burkhard Greve4, Nikos K. Karamanos1,2

University of Patras, Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry; 2Foundation for Research and Technology- Hellas (FORTH), Institute of Chemical Engineering Sciences (ICE-HT), Patras; Münster University Hospital, 3Department of Gynecology and 4Obstetrics Department of Radiotherapy–Radiooncology, Germany 1

P042 Investigating the pathophysiological role of RANKL in mammary gland development Anthi Kolokotroni1,2, Vagelis Rinotas1,2, Evi Gkikopoulou1,2, Eleni Douni1,2 1

Division of Immunology, Biomedical Sciences Research Center “Alexander Fleming”; 2Laboratory of Genetics, Department of Biotechnology, Agricultural University of Athens

P043 Bone marrow adiposity in RANKL-mediated modeled osteoporosis Vagelis Rinotas1,2, Efthymios Tzortzis1,2, Panagiota Siatra1,2, Kostas Kritikos1,2, Panagiotis Nikolaou1,2, Anthi Kolokotroni1,2, Maria Papadaki1,2, Eleni Douni1,2 1

Division of Immunology, Biomedical Sciences Research Center “Alexander Fleming”; 2Laboratory of Genetics, Department of Biotechnology, Agricultural University of Athens

P044 Evaluation of the role of ERβ in the functional properties and ECM composition of breast cancer cells A. Koutsandreas, Z. Piperigkou, N.K. Karamanos

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P045 Evaluation of photolithograpically micropatterned surfaces for guided cell adhesion, morphology and proliferation Athanasia Bourkoula1, Eleni Mavrogonatou2, Pagona Pavli3, Panagiota S. Petrou1, Antonios M. Douvas3, Panagiotis Argitis3, Dimitris Kletsas2, Sotirios E. Kakabakos1* Immunoassays/Immunosensors Laboratory, Institute of Nuclear and Radiological Sciences & Technology, Energy & Safety & 2Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications & 3Institute of Nanoscience and Nanotechnology, NCSR “Demokritos”

P046 The APC/C inhibitor Emi2 regulates entry into and exit from M-phase in mouse oocytes. Konstantina Niaka1,2, Konstantinos Stamatiou1, Eirini Bellou1, Eleni Papadopoulou1, Andromachi Lamprianidou1, Sandra Gonzalez Malagon1,2, Petros Marangos1,2* Department of Biological Applications and Technologies, University of Ioannina; 2Department of Biomedical Research, IMBB/FORTH, Ioannina

P047 Malignant pleural mesothelioma 3D phenotypes are equally sensitive to cisplatin and pemetrexed chemotherapy and pemetrexed alone Eleftherios D. Papazoglou1*, Rajesh M. Jagirdar1, Olympia Kouliou1, Chrissi Hatzoglou1,2, Konstantinos I. Gourgoulianis2, Sotirios G. Zarogiannis1,2 1

Department of Physiology & 2Department of Respiratory Medicine, Faculty of Medicine, University of Thessaly, Larissa

P048 Α toxic Microcystis (Cyanobacteria) extract affects the F-actin cytoskeleton in Oryza sativa root cells Dimitris Pappas, Spyros Gkelis, Emmanuel Panteris* Department of Botany, School of Biology, University of Thessaloniki

P049 Inhibition of JAK/STAT signaling pathway results in altered functional properties and ECM composition in ERβ-positive breast cancer cells Ch. Pentavra, Z. Piperigkou, N.K. Karamanos

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras

P050 Regulation of McIdas’ protein levels during the cell cycle Vassiliki Petroulaki1, Marina Arbi1, Andreas Panagopoulos1, Stavroula Tsaridou1, Spyridoula Mpournaka1, Stavros Taraviras2, Zoi Lygerou1,* Laboratory of Biology & 2Laboratory of Physiology, School of Medicine, University of Patras

P051 Structural characterization of the interaction between Gemc1 and p73 Margarita Skamnelou1, Ioannis Loukas1, Marina Arbi1, Maria-Eleni Lalioti2, Stavros Taraviras2, Zoi Lygerou1* 1

Laboratory of Biology & 2Laboratory of Physiology, School of Medicine, University of Patras

P052 A novel tool for distinguishing qualitatively and quantitatively the normal from pathologic nucleolus Vassiliki Stamatopoulou1*, Pascaline Parisot2, Christophe De Vleeschouwer2, Denis Lafontaine3*

Department of Biochemistry, School of Medicine, University of Patrasl; 2ICTEAM-ELEN, Université Catholique de Louvain; 3RNA Molecular Biology, F.R.S./FNRS, Université Libre de Bruxelles 1

P053 Hypoxia alters the subnuclear distribution of nuclear matrix SAFB1/2 proteins and their association with splicing factor SF2 Chrysa Taze, Sotiria Drakouli, Eleni Georgatsou, Ilias Mylonis* Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa

P054 An in silico method for the identification of nuclear localization signal of cargo proteins Athanasios Panagiotopoulos1, Hara Polioudaki2, George Notas1, Elias Castanas1, Marilena Kampa1, Panayiotis Theodoropoulos2 Laboratory of Experimental Endocrinology & 2Department of Biochemistry, School of Medicine, University of Crete, Heraklion

P055 McIdas function during the cell cycle and ciliogenesis Spyridoula Bournaka1†, Stavroula Tsaridou1†, Marina Arbi1, Vassiliki Petroulaki1, Stavros Taraviras2, Zoi Lygerou1* Laboratory of Biology & 2Laboratory of Physiology, School of Medicine, University of Patras

P056 The Parvin-ILK duet: a mechanistic insight of their interactions in Drosophila muscle junctions Katerina M. Vakaloglou, Christos G. Zervas* Biomedical Research Foundation, Academy of Athens

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P057 The roles of exonuclease EXD2 in terminal DNA repair and the Alternative Lengthening of Telomeres in neoplasia Veronica Cherdyntseva1, Theodora Evmorfopoulou1, Ronan Broderick2, Jadwiga Nieminuszczy2, Christina Raftopoulou1, Ariadni Liakopoulou1, Wojciech Niedzwiedz2, Sarantis Gagos1

Laboratory of Genetics. Center of Experimental Medicine and Translational Research, Biomedical Research Foundation of the Academy of Athens; 2The Institute of Cancer Research (ICR) Royal Cancer Hospital, London 1

P058 Mapping of the interaction between HIF-1α and Mortalin Angelos Yfantis, Ilias Mylonis, George Simos*

Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa

05. Systems Biology - Bioinformatics P059-P074 P059 Network oriented gene expression analysis in Mantle Cell Lymphoma Georgia Orfanoudaki1, Konstantina Psatha1, Anastasis Oulas2, George M. Spyrou2, Michalis Aivaliotis1,3*

ΙΜΒΒ-FORTH, Heraklion; 2Bioinformatics ERA-Chair at Cyprus Institute of Neurology and Genetics (CING); 3Lab of Biological Chemistry, School of Medicine, University of Thessaloniki 1

P060 Field synopsis and construction of association network with microRNA expression patterns and human diseases Elisavet Μ. Andronidou, Georgia G. Braliou, Panagiota I. Kontou, Pantelis G. Bagos* Department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia

P061 Genome-wide investigation of selection patterns in the Cretan population Nikos Avramidis1, Fotis Tsetsos1, Margaritis Tsifintaris1, Alexis Galanis1, Peristera Paschou2* 1

Department of Molecular Biology and Genetics, University of Thrace, Alexandroupolis; 2Department of Biological Sciences, Purdue University, USA

P062 Metabolomics of intraventricular hemorrhage preterm neonates Olga Begou1, Olga Deda2*, Kosmas Sarafidis3, Helen Gika2, Charalampos Agakidis3, Nikolaos Efstathiou3, Georgios Theodoridis1 Department of Chemistry, University of Thessaloniki; 2Laboratory of Forensic Medicine and Toxicology & 31st Department of Neonatology, School of Medicine, University of Thessaloniki 1

P063 Phosphorylation Mapping of Laminin β1-chain: Kinases in association with active sites Kleio-Maria Verrou1,2†, Panagiota Angeliki Galliou1†, Maria Papaioannou1, George Koliakos*1 1

Laboratory of Biological Chemistry, School of Medicine, University of Thessaloniki; 2School of Medicine, University of Crete; †These authors contributed equally to this work

P064 RAG recombinase and DNA sequence dependant interactors promote recurrent gene fusions in solid tumors R. Jagirdar*1, E. Papazoglou1, E. Rouka2, R. Podicheti3, C. Hatzoglou1, Konstantinos I. Gourgoulianis4, Sotirios G. Zarogiannis1 University of Thessaly, 1Dept of Physiology & 2Dept of Transfusion Medicine & 4Dept of Respiratory Medicine, Larissa; 3Indiana University, Dept of Biology, Bloomington

P065 1H NMR metabolomics in urine samples of patients with chronic kidney disease and control donors Evdokia C. Karagkouni1, Konstantina V. Matzarapi1, Styliani A. Chasapi1, Sotiris S. Vamvakas2, Dimitra Kalavrizioti2, Dimitrios S. Goumenos2, Georgios A. Spyroulias1* 1

Department of Pharmacy, University of Patras; 2Nephrology and Transplant Center, University General Hospital, Patras

P066 Comparative study of the inhibition of ochratoxin A-induced cytotoxicity to HEK293 cells by several antioxidants followed by GC/EI/MS metabolomics analysis Sophia Marka1, Sophia Mavrikou1*, Konstantinos A. Aliferis2,3, Maira Lykogianni2, Eleni Douni1,4, Spyridon Kintzios1 1 4

Department of Biotechnology & 2Laboratory of Pesticide Science, Agricultural University of Athens; 3Department of Plant Science, McGill University, Montreal, Canada; Division of Immunology, Biomedical Sciences Research Center ‘Alexander Fleming’

P067 Large-scale genomic analysis reveals recurrent patterns of intertypic recombination in human Enteroviruses Marios Nikolaidis1, Kalliopi Mimouli1, Zaharoula Kyriakopoulou2, Michail Tsimpidis1, Dimitrios Tsakogiannis2, Panayotis Markoulatos2, Grigoris D. Amoutzias1* 1

Bioinformatics Laboratory & 2Molecular Virology Laboratory, Department of Biochemistry and Biotechnology, University of Thessaly, Larisa

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P068 Towards identifying novel potential anti-tumor targets of octreotide through structural modeling and docking Panagiota Papanagnou1*, Georgios E. Papadopoulos2, Theodora Stivarou3, Anastasios Pappas1

Department of Urology, Agios Savvas Cancer Hospital, Athens; 2Department of Biochemistry & Biotechnology, University of Thessaly, Larissa; 3Immunology Laboratory, Immunology Department, Hellenic Pasteur Institute 1

P069 Bioenergetic diversity of the gut microbiome, and relation to disease Konstantinos Papasakellariou, Vassiliki Lila Koumandou* Department of Biotechnology, Agricultural University of Athens

P070 Data processing approach for the construction and evaluation of an organism’s UNIQUOME Vasileios Pierros1, Evangelos Kontopodis1, Athanasios K. Anagnostopoulos1, George Th. Tsangaris1 Proteomics Research Unit, Biomedical Research Foundation of the Academy of Athens

P071 OMIC-ENGINE: The University of Patras Hub Maria D. Politi, Sofia-Antigoni Tsatsouli, Zoi Zagoriti, Gozde Isik-Andrikopoulos, Aristeidis Ntoukas, Panagiota Perari, Athanasios Drosos, Konstantinos Poulas, Georgios A. Spyroulias Department of Pharmacy, University of Patras

P072 ELIXIR-GR: Bioinformatics tools for analysis of next-generation sequence data and an application example Margaritis Tsifintaris1, Fotis Tsetsos1, Apostolos Manolis2, Aristotelis Papageorgiou2, Alexis Galanis1, Peristera Paschou1* Department of Molecular Biology and Genetics, University of Thrace, Alexandroupolis; Department of Forestry and Management of the Environment and Natural Resources, University of Thrace, Orestiada

1 2

P073 Radiogenomic analysis of Positron Emission Tomography and gene expression data suggests a composite signature for robust Colorectal Cancer patient characterization Efstathios-Jason Vlachavas1,2,3, Eleftherios Pilalis1,3, Olga Papadodima1, Dirk Koczan4, Stefan Willis5, Sven Klippel5, Caixia Cheng6, Leyun Pan6, Christos Sachpekidis6, Antonia Dimitrakopoulou-Strauss6, Aristotelis Chatziioannou1,3* Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens; 2Department of Molecular Biology and Genetics, University of Thrace; 3Enios Applications Private Limited Company, Athens; 4Core Facility Micro-Array-Technology, Center of Medical Research, University of Rostock; 5Surgical Clinic A, Klinikum Ludwigshafen; 6Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg 1

P074 Profiling of Regulated IRE1-dependent mRNA degradation (RIDD) cleavage sites by motif discovery and RNA structure prediction Konstantinos Voutetakis1,2, Efstathios-Jason Vlachavas1,3, Dimitrios Doultsinos4,5, Eric Chevet4,5, Aristotelis Chatziioannou1,3*

Institute of Biology, Medicinal Chemistry & Biotechnology, NHRF, Athens, Greece, 2 Department of Biochemistry & Biotechnology, University of Thessaly, Larissa, Greece e-NIOS PC, Kallithea-Athens, Greece, 4 INSERM, ERL440, “Oncogenesis, Stress, Signaling”, Université de Rennes 1, Rennes, France, 5 Centre de LutteContre le Cancer Eugène Marquis, Rennes, France 1 3

06. Chemical Biology P075-P084 P075 Vitamin D metabolizing enzymes: expression and expression regulation by natural products in Huh7 cells. Antonia-Eugenia Angeli-Terzidou1, Eleni Kechagia1, Kalliopi Pazaitou-Panayiotou2, Andreas Tsakalof1* 1

Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa; 2Department of Endocrinology, Theagenio Cancer Hospital, Thessaloniki

P076 A novel curcumin-based V(IV) complex and its interaction studies with bovine serum albumin and DNA Dimitrios Avgoulas1, Eleftherios Halevas1,2, Georgios Katsipis1, Athanasios Salifoglou1, Georgios Litsardakis1, Georgios Geromichalos1, Anastasia Pantazaki1* 1

University of Thessaloniki; 2Institute of Nanoscience and Nanotechnology, N.C.S.R. “Demokritos”, Athens

P077 Mitochondriotropic hyperbranched polymeric nanocarriers for drug repositioning Archontia Kaminari1, Katerina Panagiotaki1, Zili Sideratou1, Spyros Vlahopoulos2, Dimitris Tsiourvas1* 1

Institute of Nanoscience and Nanotechology, NCSR ‘‘Demokritos”, Attiki; 2Horemeio Research Laboratory, First Department of Paediatrics, University of Athens

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P078 Biological evaluation of a novel complex V(IV) based on curcumin, as a potential antifungal, anti-radical and anti-amyloid agent. Georgios Katsipis1, Eleftherios Halevas1,2, Maria Karagkiaouri1, Georgios Litsardakis1, Athanasios Salifoglou1, Anastasia Pantazaki1* 1

University of Thessaloniki; 2Institute of Nanoscience and Nanotechnology, N.C.S.R. “Demokritos”, Athens

P079 Haemolytic activity and cytotoxicity of calcium silicate nanoparticles doped with magnesium Konstantina Kazeli1, Ioannis Tsamesidis2, Anna Theocharidou4, Georgia Pouroutzidou3, Georgios Theodorou3, Triantafyllia Zorba3, Eleana Kontonasaki4, Theodoros Lialiaris1, Evgenia Lymperaki2*

University of Thrace, Alexandroupoli; 2Alexandrion Technological Institute, Thessaloniki; 3Department of Physic & 4 Department of Fixed Prosthodontics, University of Thessaloniki 1

P080 ABSTRACT WITHDRAWN P081 Editing the immunopeptidome of melanoma cells using a potent inhibitor of ER aminopeptidase 1 Despoina Koumantou1, Eilon Barnea2, Adrian Martin-Esteban5, Zachary Maben4, Athanasios Papakyriakou1, Paraskevi Kokkala3, Harris Pratsinis1, Dimitris Georgiadis3, Lawrence J. Stern4, Arie Admon2, Efstratios Stratikos1,* National Center for Scientific Research Demokritos, Athens; 2Faculty of Biology, Technion - Israel Institute of Technology; 3Laboratory of Organic Chemistry, Chemistry Department, University of Athens; 4Department of Pathology, University of Massachusetts Medical School; 5 Centro de Biologia Molecular Severo Ochoa, Madrid 1

P082 Biological evaluation of a Re(I) tricarbonyl complex with the anticancer agent 2-(4΄-aminophenyl)benzothiazole for tumor therapy B. Mavroidi1, M. Sagnou1, I. Roupa2, C. Methenitis3, M. Paravatou-Petsotas2, I. Pirmettis2, M. Papadopoulos2, M. Pelecanou1*

Institute of Biosciences & Applications & 2Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research “Demokritos”, Athens; 3 Inorganic Chemistry Laboratory, Department of Chemistry, University of Athens 1

P083 Correlation of atherosclerosis with oxidative stress and diet antioxidants Diana Samara1, Kiriaki Papadopoulou2, Polyxeni Nikza3, Efthimia Torbantoni3, Ioannis Tsamesidis1, Agathi Pritsa2, Evgenia Lymperaki1* Department of Medical Laboratory Science & 2Department of Nutrition and Dietetics, Alexander Technological Institute, Thessaloniki; 3General Hospital, Naousa

P084 A newly-synthesized vanadium(IV)-curcumin complex as a potential inhibitor of bacterial alkaline phosphatase and its role in biofilm formation Viktoria Tsalouchidou1, Georgios Katsipis1, Eleftherios Halevas1,2, Athanasios Salifoglou1, Georgios Litsardakis1 , Anastasia Pantazaki1* University of Thessaloniki; 2Institute of Nanoscience and Nanotechnology, N.C.S.R. “Demokritos”

07. Functional Genomics-Proteomics P085-P090 P085 Exploring the reproductive system of the olive fly, Bactrocera oleae Maria-Eleni Gregoriou1, Martin Reczko2, Konstantina Tsoumani1, Kostas Mathiopoulos1* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa Institute of Molecular Biology and Genetics, Biomedical Sciences Research Centre “Alexander Fleming”

1 2

P086 DNA damage and repair at the distinct compartments of the mammalian nucleus Alkmini Kalousi, Céline Bonhomme, Sylvain Audibert, Evi Soutoglou* Institut de gén3étique et de biologie moléculaire et cellulaire, IGBMC, Illkirch, France

P087 Proteomics Analysis of Greek Goat Whey Colostrum Artemis G. Korovesi*, Angeliki I. Katsafadou, George Th. Tsangaris, Athanasios K. Anagnostopoulos Proteomics Research Unit, Center of Basic Research II, Biomedical Research Foundation of Academy of Athens

P088 Proteomics analysis of Hepatitis C core+1/ARFP protein Savvina Moustafa1,2, Ioannis Karakasiliotis1,3, Katerina Katsani2, Manousos Makridakis4, Jeronymos Zoidakis4, Antonia Vlahou4, Penelope Mavromara1,2 Hellenic Pasteur Institute, Athens; 2Department of Molecular Biology and Genetics & 3Department of Medicine, Democritus University of Thrace, Alexandroupoli; Biotechnology Division, Biomedical Research Foundation of the Academy of Athens

1 4

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P089 Τhe interplay between autophagy and exosomal pathways in Hodgkin and non-Hodgkin lymphoma cells following p53 activation Aikaterini Kalantidou#1, Anna-Aspasia Karkavitsa#1, Eirini Papadaki2, Chara Karantoni2, Georgia Orfanoudaki3, Elias Drakos4, Konstantina Psatha*3, Michalis Aivaliotis*3,5 1 Department of Biology & 2Department of Chemistry & 4School of Medicine, University of Crete, Heraklion; 3Institute of Molecular Biology and Biotechnology Foundation for Research and Technology-Hellas, Heraklion; 5Laboratory of Biochemistry, School of Medicine, University of Thessaloniki

P090 The effect of CMV and PVY infection and cold stress on the expression of the genes involved in the putrescine biosynthesis of tomato leaves. Polyxeni Pappi1, Georgios Tsaniklidis2

National Agricultural Research Foundation (NAGREF) Hellenic Agricultural Organization (HAO) DIMITER. Institute of viticulture, floriculture, vegetable crops and plant protection of Heraklion. 1 Laboratory of Virology & 2Laboratory of Vegetable production

08. RNA Biology P091-P100 P091 Poly(A)-specific ribonuclease variants in pleural malignant mesothelioma Dionysios Antonopoulos1*, Anna Politi1, Dimitra Stergiou1, Athanasios Kyritsis1,2, Rafailia A.A. Beta1, Konstantinos I. Gourgoulianis2, Nikos Balatsos1 1

Department of Biochemistry and Biotechnology & 2Department of Medicine, University of Thessaly, Larissa

P092 In silico identification and experimental validation of novel transcripts of the members of the apoptosis-related BCL2 family in human cell lines Pinelopi I. Artemaki, Panagiotis G. Adamopoulos, Andreas Scorilas, Christos K. Kontos* Department of Biochemistry and Molecular Biology, University of Athens

P093 Effects of Lupus antigen (La) expression in transcription and translation components in lung cancer Eleni Kaliatsi1, Athanasios-Nasir Shaukat1, Ilias Skeparnias1, Aikaterini I. Argyriou2, Georgios A. Spyroulias2, Constantinos Stathopoulos1 1

Department of Biochemistry, School of Medicine & 2Department of Pharmacy, University of Patras

P094 HSPB2 gene transcription is downregulated in breast cancer, while its upregulation is associated with breast cancer patients’ relapse Aimilia D. Sklirou1, Evdoxia Kamouza2, Despoina D. Gianniou1, Maria-Christina Cheimonidi1, Christos K. Kontos2, Andreas Scorilas2, Ioannis P. Trougakos1* 1

Department of Cell Biology and Biophysics & 2Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens

P095 Molecular characterization, genomic structure, and expression analysis of the CATL1 (CPT1C) gene, a third member of the human carnitine acyltransferase family Christos K. Kontos, Panagiotis G. Adamopoulos, Andreas Scorilas Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens

P096 The phosphorylation status of mRNA binding protein IMP1 regulates c-MYC expression levels. Andromachi Lambrianidou1, Evangelia Sereti2, Konstantinos Dimas2, Theoni Trangas1*.

Biochemistry Lab, Department of Biological Applications and Technology, University of Ioannina; 2Department of Pharmacology, Faculty of Medicine, University of Thessaly, Larissa 1

P097 Hypoxia-inducible factor-1 (HIF1) and its master regulators, miR-155-5p and miR-92a-3p, compose a molecular prognostic signature in chronic lymphocytic leukemia Aikaterini-Anna Liosi1*, Sotirios G. Papageorgiou2, Panagiotis Tsiakanikas1, Marios A. Diamantopoulos1, Vasiliki Pappa2 1 2

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens; Second Department of Internal Medicine and Research Unit, University General Hospital “Attikon”, Athens

P098 RNase ZS CRISPR-Cas9 knockout results in viable cells with differential stress response and translation regulation Athanasios-Nasir Shaukat, Eleni Kaliatsi, Ilias Skeparnias, Constantinos Stathopoulos* Department of Biochemistry, School of Medicine, University of Patras

P099 Neuronal silencing of the mRNA decapping enzyme subunit 1 (DCP1) affects larval wing www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

disc morphogenesis and adult wing expansion in Drosophila melanogaster. John Rallis, Popi Syntichaki, Christos G. Zervas* BRFAA, Athens

P100 Knockdown and overexpression of PNLDC1 deadenylase modulate stem and somatic cells physiology with opposing mechanisms Ilias Skeparnias1, Christos Katsioulas1, David Dermoniotis1, Dimitrios Anastasakis1,2, Athanasios-Nasir Shaukat1, Katerina Grafanaki1, Constantinos Stathopoulos1*

Department of Biochemistry, School of Medicine, University of Patras; 2RNA Molecular Biology Group, Laboratory of Muscle Stem Cells and Gene Regulation, NIAMSD, NIH, USA. 1

SESSION B – SATURDAY 24th November 2018 09. Regulation of Gene Expression P101-P110 P101 Differential gene expression profiling of Dsg1 and Dsg3 in HSC-3 and U87 MG cells grown as multicellular aggregates (MCAs) in vitro Melpomeni G. Akrivou1, Konstantinos A. Kyritsis1, Ioannis S. Vizirianakis1* 1

Laboratory of Pharmacology, School of Pharmacy, University of Thessaloniki

P102 The role of histone demethylases PHF2 and PHF8 in macrophage activation and inactivation; the implication of metabolic genes Maria G. Daskalaki1,2, Eleftheria Ieronymaki2, Konstantina Lyroni2, Christos Tsatsanis2 1

Department of Biochemistry & 2Department of Clinical Chemistry, School of Medicine, University of Crete, Heraklion

P103 TNF-α inhibits hypoxic stimulation of HIF-2α transcriptional activity by impairing its interaction with ARNT Aikaterini Diseri1, Ioanna-Maria Gkotinakou1, Εva Pangou1,2, Panagiotis Liakos1* 1 2

Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa Present address: Department of Biology and Stem Cell Development, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg

P104 Protein phosphatase PDP1 regulates HIF activity Angeliki Karagiota, Ilias Mylonis, George Simos, Georgia Chachami* Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa

P105 Epigenetic regulation of Breast Cancer Stem cell properties John Verigos1,2 +, Dimitris Kordias1,2 +, Angeliki Magklara1,2 *

Department of Biomedical Research, Institute of Molecular Biology & Biotechnology, FORTH, Ioannina; 2Laboratory of Clinical Chemistry, Faculty of Medicine, University of Ioannina 1

P106 KRASG12C mutation differentially rewires protein synthesis via c-MYC-modulated translation initiation recruitment in NSCLC George Kyriakopoulos#, Vicky Katopodi#, Ilias Skeparnias, Katerina Grafanaki, Constantinos Stathopoulos* Department of Biochemistry, School of Medicine, University of Patras

P107 In vitro antioxidant effects of balsam extracts and oils on primary human fibroblasts Elisavet Lykoudi1, Ioanna Anastasiou1, Sophia Letsiou2, Kostantinos Gardikis2, Emmanouil Flemetakis1*

Agricultural University of Athens, Department of Biotechnology, Laboratory of Molecular Biology; 2Laboratory of Biochemistry, Scientific Affairs Department, APIVITA S.A., Athens 1

P108 The effect of Bone Morphogenetic Protein -2 (BMP-2) on the expression of transcription factor and tumor marker ZNF217 in human mesenchymal stem cells Aglaia Mantsou*, Paraskevas Lamprou, Stylianos Zafeirios Karoulias, Theodora Choli-Papadopoulou Laboratory of Biochemistry, School of Chemistry, University of Thessaloniki

P109 Establishing a role of the mRNA decapping complex in the regulation of innate immune response in the nematode Caenorhabditis elegans Dimitra Ranti1,2, Fivos Borbolis1, Maria-Despina Papadopoulou3, Apostolos Malatras3,4, Theologos Michaelidis2, Ioannis Michalopoulos3, Popi Syntichaki1,*

Center of Basic Research & 3Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens; 2Department of Biological Applications & Technology, University of Ioannina; 4Center for Research in Myology, Sorbonne Universités 1

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P110 miR-342-3p targets link the canonical NF-κB pathway with regulators of cell proliferation in lung cancer Maria Tokamani1, Elpida Ziridou1, Kanela Kafetzopoulou1, Sofia Mourati1, Christina Niavi1, George Markopoulos2, Eugenia Roupakia2, Evangelos Kolettas2, Raphael Sandaltzopoulos1* Dept. of Molecular Biology and Genetics, University of Thrace, Alexandroupolis; 2Laboratory of Biology, School of Medicine, University of Ioannina & Biomedical Research Division, Institute of Molecular Biology & Biotechnology, Foundation for Research & Technology, Ioannina 1

10. Molecular & Genetic Basis of Diseases P111-P159 P111 Notch pathway early activation in a uPA-deficient mouse model of inflammationassociated colorectal carcinogenesis Hara Afaloniati1, George S. Karagiannis2, Emmanouel Karavanis3, Theophano A. Psarra4, Theofilos Poutahidis5, Katerina Angelopoulou1*

Laboratory of Biochemistry and Toxicology & 4Laboratory of Pharmacology & 5Laboratory of Pathology, School of Veterinary Medicine, University of Thessaloniki; Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York; 3Histology-Histopathology Laboratory, C’ Army Veterinary Hospital, Thessaloniki 1

P112 Potential anticancer effect of antipsychotic drugs: in vitro investigation in NSCLC cell lines Christina Andriopoulou, Paraskevi Kirgou, Periklis Pappas, George Leondaritis, Maria Konstandi Department of Pharmacology, Faculty of Medicine, University of Ioannina, Ioannina

P113 Unravelling the role of ILK and PINCH in tumour angiogenesis and vascular morphogenesis Christina Arapatzi, Pinelopi Nikolopoulou, Vassiliki Kostourou BSRC Alexander Fleming, Vari

P114 Unveiling synthetic lethal interactions in defective DNA replication licensing Nibal Badra1, Michalis Petropoulos1, Marina Arbi1, Andreas Panagopoulos1 Juha K. Rantala2, Stavros Taraviras3, Zoi Lygerou1* 1

Department of General Biology & 3Department of Physiology, School of Medicine, University of Patras; 2Misvik Biology, Turku, Finland

P115 Bleomycin revisited: A direct comparison of the intratracheal micro-spraying and the oropharyngeal aspiration routes of bleomycin administration in mice Iliana Barbayianni1*, Ioanna Ninou1, Argyrios Tzouvelekis1, Vassillis Aidinis1 1

Division of Immunology, Biomedical Sciences Research Center “Alexander Fleming”

P116 MiR-24-3p and let-7f-5p exhibit deregulated expression patterns in patients with type-2 diabetes mellitus and individuals with risk factors for the disease, as revealed by semihigh throughput blood-based analysis Maria-Ioanna Christodoulou1, Margaritis Avgeris1, Ioanna K. Kokkinopoulou1, Eirini Maratou2, Panagiota Mitrou3, Eleni Boutati2, Andreas Scorilas1, Emmanuel G. Fragoulis1

Department of Biochemistry and Molecular Biology, School of Biology & 22nd Department of Internal Medicine, Research Institute and Diabetes Center, University General Hospital Attikon, Medical School, University of Athens; 3Ministry of Health, Athens 1

P117 Investigation of the effect of anthocyanin rich extracts in neoplastic protection Marilena Christoforou1*, Eirini Kanata2, Konstantinos Xanthopoulos2, Tatiana Tsoukni2, Anastasia Karioti2, Theodoros Sklaviadis2, Dimitra Dafou1 1

Department of Genetics, Development and Molecular Biology, School of Biology & 2School of Pharmacy, University of Thessaloniki

P118 The role of Myeloperoxidase in generating dysfunctional HDL particles in vivo Katerina Dalakoura – Karagkouni1,2*, Ioanna Tiniakou3, Dimitris Kardassis1,2

Laboratory of Biochemistry, School of Medicine, University of Crete, Heraklion; 2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion; 3Department of Pathology, Langone Medical Center, New York University 1

P119 Investigating the role of Cdt1 and Geminin in colon tumorigenesis Iosif Rodolfos Danalatos1, Michalis Petropoulos1,2, Spyridon Champeris Tsaniras1,2, Zoi Lygerou2, Stavros Taraviras1* 1

Department of Physiology & 2Department of Biology, Medical School, University of Patras

P120 Lipocalin 2 (Lcn2) is upregulated in Idiopathic Pulmonary Fibrosis (IPF) in mice Apostolos Galaris*, Iliana Barbayianni, Katerina Touloumi, Vassillis Aidinis Division of Immunology, Biomedical Sciences Research Center “Alexander Fleming”

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69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P121 A novel approach to design and dynamically measure in vitro the biological activity of IAPP analogues designed by ancestral gene reconstruction for more efficient treatment of diabetes type-2 Anastasios Georgoulis1*, Anna Papageorgiou1, Panagiotis Adam1, Constantinos Vorgias1 University of Athens, Faculty of Biology, Department of Biochemistry and Molecular Biology

P122 Generation of recombinant HSV-1 viruses expressing EGFP and luciferase reporter genes for use in antiviral drug screening Konstantinos D. Gerakoudis1, Sotirios G. Ntallis1, Stavroula Litsiou1, Georgios Kampouridis2, Dimitra HadjipavlouLitina2, Christos A. Panagiotidis1* 1

Laboratory of Pharmacology & 2Laboratory of Pharmaceutical Chemistry, School of Pharmacy, University of Thessaloniki

P123 Cytokine production in innate immune cells infected with Murine Norovirus Glykeria Gkoliou1, Georgios Aindelis1, Katerina Spyridopoulou1, Ioannis Karakasiliotis2, Katerina Chlichlia1 1

Department of Molecular Biology and Genetics & 2Department of Medicine, University of Thrace, Alexandroupolis

P124 The role of XPC PAT+/-, XRCC3 rs861539, XRCC1 rs25481 and XPD rs13181 SNPs in breast carcinogenesis. Aikaterini Chatzouli, Eleni Avdoula, Maria Papathanassiou, Maria Ioannou, Roidoula Papamichali, George Koukoulis, Maria Samara1* Department of Pathology, Faculty of Medicine, University of Thessaly, Larissa

P125 Akt isoforms are central regulators of insulin signalling and metabolic status of macrophages Eleftheria Ieronymaki, Konstantina Lyroni, Maria G. Daskalaki, Christos Tsatsanis* Dept of Clinical Chemistry, University of Crete Medical School, Heraklion

P126 CagA-dependent upregulation of epithelial-to-mesenchymal-transition mediators upon Helicobacter pylori infection Yiannis Karayiannis1, Eleftherios Kontizas1, Beatriz Martinez-Gonzalez1, Kalliopi Petraki2, Andreas Mentis1, Panagoula Kollia3, Dionyssios Sgouras1

Laboratory of Medical Microbiology, Hellenic Pasteur Institute; 2Department of Pathology, Metropolitan Hospital, Athens; 3Department of Genetics and Biotechnology, Faculty of Biology, University of Athens 1

P127 Gender-specific transcriptomics in Î˛-thalassaemia Aikaterini Nanou1, Chrisavgi Toumpeki1, Pavlos Fanis2, Nicoletta Bianchi3, Lucia Carmela Cosenza3, Cristina Zuccato3, Giorgos Giagkas1, Coralea Stephanou2, Marios Phylactides2, Soteroula Christou4, Carsten Lederer2, Roberto Gambari3, Marina Kleanthous2, Eleni Katsantoni1*

Basic Research Center, Biomedical Research Foundation, Academy of Athens; 2Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia; 3Department of Life Sciences and Biotechnology, Ferrara University; 4Thalassaemia Clinic, Archbishop Makarios III Hospital, Nicosia 1

P128 Dissecting the pathobiology of paediatric coeliac disease reveals genetic risk variants linked to comorbidities; an immunogenomics paradigm Angeliki Balasopoulou1, Angeliki Panagiotara1, Dimitrios Kampolis1, Constantina Chalikiopoulou, Fotini Gerasimatou1, Maro Krini2, Anne John3, Kleopatra Spanou4, Bassam R. Ali3, Maria Kanariou4, Nikki Constantinidou4, George Chrousos2, Eleftheria Roma2, George P. Patrinos1,3, Theodora Katsila1* Department of Pharmacy, University of Patras; 2First Department of Pediatrics, University of Athens Medical School; 3Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain; 4Department of Immunology and Histocompatibility, Aghia Sophia Childrenâ&#x20AC;&#x2122;s Hospital, Athens 1

P129 Gene expression levels of phosholipases A2 isoforms in tissue samples of colon cancer patients Stelios Papadopoulos1, Evangelos Falidas2, Angelos Pazidis3, Mihalis Mitsis3, Dimitrios Nastos3, Maria Eleni Lekka1, Konstantinos Vlahos3*, Eirini Kitsiouli1* 1

Biochemistry Laboratory, Chemistry Department & 3Department of Surgery, School of Medicine, University of Ioannina; 2Department of Surgery, General Hospital of Chalkida

P130 Deficiency of Akt1 kinase improves clearance of Group Beta streptococcus (GBS) in adult and neonatal macrophages by enhancing autophagy and autophagy-related pathways. Ourania Kolliniati, Christos Tsatsanis, Eleni Vergadi 1

University of Crete, Heraklion; 2Department of Clinical Chemistry, Medical School, Heraklion

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P131 Putative role of CagA oncoprotein on the Helicobacter pylori infection-mediated DNA damage repair modulation Eleftherios Kontizas1,3, Spiros Tastsoglou2, Timokratis Karamitros1, Yiannis Karayiannis1,3, Chrysoula Kartsiouka1, Panagoula Kollia3, Artemis Hatzigeorgiou2, Andreas Mentis1, Dionyssios Sgouras1*

Laboratory of Medical Microbiology, Department of Microbiology & 2DIANA-Lab, Hellenic Pasteur Institute, Athens; 3Department of Genetics and Biotechnology, Faculty of Biology, University of Athens 1

P132 Changes in the biological behavior of 22Rv1 prostate cancer cells before and after development of xenografts in female and male SCID mice Elisavet Kormentza*1, Eleni Papadaki1, Katerina Skeva1, Vasiliki Toufaki1, Christos Kakouratos1, Achilleas Mitrakas1, Alexandra Giatromanolaki2, Michael I. Koukourakis1 1

Department of Radiotherapy/Unit of Oncology-Radiobiology & 2Department of Pathology, School of Medicine, University of Thrace, Alexandroupolis

P133 Angiogenesis regulators in PIK3CA mutated colon cancer cell lines: The role of CXCL5 Anastasia Kougioumtzi1,4, Athena Kyrkou1, Angelos Papadopoulos1, Anna Batistatou3, Argiris Efstratiadis2, Carol Murphy1, Theodore Fotsis1,4*

FORTH, Institute of Molecular Biology & Biotechnology – Department of Biomedical Research; 2Department of Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation, Academy of Athens; 3Department of Pathology, Ioannina University Hospital; 4Laboratory of Biological Chemistry, Faculty of Medicine, University of Ioannina 1

P134 miR-21-5p as potential biomarker in Greek patients with Systemic Lupus Erythematosus Maria Kourti, Maria Sokratous, Christina G. Katsiari

Department of Rheumatology & Clinical Immunology, Faculty of Medicine, University of Thessaly & University General Hospital of Larissa

P135 Molecular genotyping of papillary thyroid carcinoma in a Greek cohort Maria Lala1, Vasiliki Pantazopoulou1, Nikolas Kalavros1, Christina Diamanti1, Vasileios Pierros1, Dimitrios J. Stravopodis2, Stella Georgiou1, Sofia Tseleni-Balafouta3, Ema Anastasiadou1*

Biomedical Research Foundation of the Academy of Athens (BRFAA); 2Department of Cell Biology and Biophysics, Faculty of Biology & 3Department of Pathology, Medical School, University of Athens 1

P136 The importance of macrophage metabolism in gut microbiota regulation in insulin resistance and obesity Konstantina Lyroni*, Eleftheria Ieronymaki, Maria G. Daskalaki, Christos Tsatsanis University of Crete Medical School, Heraklion

P137 Protective Effect of Quercetin against Oxidative Stress-Induced Cytotoxicity in Chinese hamster ovary (CHO) and CHO- Telomerase Reverse Transcriptase (TERT) cells Angeliki Malamidou, George Koliakos, Anastasia Pantazaki* University of Thessaloniki

P138 Decreased expression of the proteoglycan decorin fills in the tumor-promoting phenotype of ionizing radiation-induced senescent human breast stromal fibroblasts Eleni Mavrogonatou1, Adamantia Papadopoulou1, Harris Pratsinis1, Eleni Liakou1, Sophia Rizou2, Konstantinos Evangelou2, Petros N. Panagiotou3, Nikos K. Karamanos4, Vassilis G. Gorgoulis2, Dimitris Kletsas1*

Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research “Demokritos”, Athens; 2Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, University of Athens; 3 Department of Plastic Surgery and Burns Unit, KAT General Hospital of Athens; 4Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras 1

P139 Chromosomal abnormalities in 1120 products of conception collected in Greece and cytogenetic analysis of two rare cases Aristotelis Moulistanos1, Eleni Sekerli2, Antonia Arampatzi2, Sofia Charisiou2, Georgios Efstathiou2, Eirini Oikonomidou2, Nikos Peroulis2, Katerina Kontopikou2, Angeliki Malamidou1, Anastasios Xefteris2* 1

University of Thessaloniki; 2Eurogenetica MSA, Thessaloniki

P140 Abrogation of DNA replication licensing control leads to Copy Number Variations across evolution Patroula Nathanaidilou1, Michalis Petropoulos1, Styliani Maxouri1, Eirini Kasselimi1, Vladimir Benes3, Stavros Taraviras2, Zoi Lygerou1* 1

Laboratory of General Biology & 2Laboratory of Physiology, Department of Medicine, University of Patras; 3Genomics Core Facility, EMBL, Heidelberg, Germany

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P141 Co-morbidities in a genetic model of heart failure: Lung and kidney manifestations and the Galectin-3 effect in the desmin-null mouse Konstantinos Ntatsoulis1, Eugenia Synolaki2, Konstantina Stathopoulou1, Aristidis S. Charonis2, Paschalis Sideras2, Yassemi Capetanaki1, Stelios Psarras1* 1

Center of Basic Research and 2Center of Clinical and Translational Research, Biomedical Research Foundation, Academy of Athens (BRFAA)

P142 Treatment with crocin normalizes blood plasma metabolic profile and ameliorates myocardial metabolic dysfunction in STZ-induced diabetic rats Dimitra Palioura*, Konstantinos Feidantsis, Antigone Lazou Laboratory of Animal Physiology, School of Biology, University of Thessaloniki

P143 Overexpression of miR-203 in ovarian carcinoma results in poor response to chemotherapy and the shorter survival outcome of the patients Konstantina Panoutsopoulou1, Margaritis Avgeris1, Viktor Magdolen2, Andreas Scorilas1,* 1 2

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens; Department of Obstetrics and Gynecology, Technical University of Munich

P144 The role of Talin1 in the RIP1-Tag2 pancreatic cancer mouse model Vasiliki Papadaki, Gina Rouni, Pinelopi Nikolopoulou, Christina Arapatzi, Vassiliki Kostourou* BSRC Alexander Fleming

P145 Immunohistochemical study of GAL-3 protein and its prognostic impact in breast cancer; correlation with clinicohistopathological parameters. Vasiliki Papadatou1*, Dimitra Gerontidi1, Stylianos Tologkos1, Ioanna Balgkouranidou1, Alexandros Maroudas1, Maria Gkomini1, Loukas Yorkas1, Stavroula Veletza2, Grigorios Tripsianis3, Maria Lambropoulou1 Laboratories of 1Histology-Embryology, 2Medical Biology and 3Medical Statistics, Department of Medicine, University of Thrace, Alexandroupolis

P146 Cholesterol and phospholipid distribution pattern in the erythrocyte membranes of patients with obstructive sleep apnoea syndrome. Charalampos Papadopoulos1*, Paschalis Steiropoulos2, Ioannis Tentes1 1

Laboratory of Biochemistry, Department of Medicine, University of Thrace, Alexandroupolis; 2Pulmonology Clinic, University Hospital of Alexandroupolis

P147 Study of promoter methylation levels of Vimentin and Twist genes as epigenetic biomarkers in adenomas and colorectal carcinomas. Maria Papathanassiou1, Panagiotis Liakos2, Maria Ioannou1, George Koukoulis1, Maria Samara1* 1

Department of Pathology & 2Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa

P148 Genotypic investigation of the Ile655Val HER2 gene polymorphism in women population diagnosed with breast cancer in Greece Androniki Papoutsi1*, Alexandros Pantelios1,2, Theodoros Lialiaris2, Urania Giannakou1, Stavroula Pervana3, Elissavet Pazarli3, Stilianos Katsaros3, Ioannis Efstratiou3 Dept. of Medical Laboratory Studies, ATEITh, Thessaloniki; 2Medical School, University of Thrace, Alexandroupolis; 3Dept.of Pathology, Papageorgiou General Hospital of Thessaloniki 1

P149 Routine SERPING1 genotyping by targeted NGS: New pathogenic variants Faidra Parsopoulou1,2, Gedeon Loules1, Maria Zamanakou1, Sofia Vatsiou1,2, Fotis Psarros3, Thalia Stefanaki4, Grzegorz Porebski5, Anna Valerieva6, Dumitru Moldovan7, Markus Magerl8, Matthaios Speletas2, Henriette Farkas9, Anastasios E. Germenis1,2,*

CeMIA SA, Larissa; 2Department of Immunology & Histocompatibility, University of Thessaly, Faculty of Medicine, Larissa; 3Department of Allergology, Navy Hospital, Athens; Allergiologist, Ioannina; 5Department of Clinical and Environmental Allergology, Jagiellonian University Medical College; 6Clinic of Allergy and Asthma, Medical University of Sofia; 7University of Medicine and Pharmacy, Romania; 8Department of Dermatology and Allergy, CharitĂŠ - UniversitĂ¤tsmedizin Berlin; 9Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest 1 4

P150 Genetic profile of mouse embryonic liver after maternal caloric limitation Christina Petropoulou, Dionysios Chartoumpekis, Athanasios Niarchos, Panagiota Batzali, Ioannis Habeos* Department of Internal Medicine, Division of Endocrinology, School of Medicine, University of Patras

P151 BNN27 exerts significant anti-inflammatory effects on T-lymphocytes derived from mice following CFA-induced inflammation Smaragda Poulaki1, Achille Gravanis2, Maria Venihaki1* 1

Department of Clinical Chemistry & 2Department of Pharmacology, School of Medicine, University of Crete, Heraklion

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P152 Therapeutic approach and investigation of alpha-synuclein protein interactions in a yeast model of Parkinson’s Disease Evangelos Sfikas, Despoina Gkeka2,3, Savvas Christoforidis2,3, Martina Samiotaki4, Efstathios Hatziloukas1, Theologos Michaelidis1, Amalia-Sofia Afendra*1

Department of Biological Applications and Technologies & 3Laboratory of Biological Chemistry, Department of Medicine, University of Ioannina; 2Institute of Molecular Biology and Biotechnology-Biomedical Research, FORTH; 4Biomedical Sciences Research Center “Alexander Fleming” 1

P153 P153 Isoform RANK-c affects stem cell properties of breast cancer cells Chaido Sirinian1, Michael Schizas2, Magda Spella3, George Stathopoulos3, Ioannis K. Zarkadis4, Haralabos P. Kalofonos1, Anastasios D. Papanastasiou1,*

Molecular Oncology Laboratory & 3 Laboratory for Molecular Respiratory Carcinogenesis & 4Department of Biology, School of Medicine, University of Patras; 2Department of Surgery, Memorial Sloan Kettering Cancer Center, New York 1

P154 Hyaluronan synthesis inhibition results in potent onco-suppressive effects in breast cancer cells Theodoros Karalis1, Athanasios Chatzopoulos1, Nikos K. Karamanos1, Paraskevi Heldin2, Spyros S. Skandalis1

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras; 2Department of Medical Biochemistry and Microbiology, Uppsala University 1

P155 Molecular evaluation of the possible prognostic significance of MTA-1 protein in patients with endometrial cancer. Stylianos Tologkos1*, Nikolaos Kesesidis1, Vasiliki Papadatou1, Ioanna Balgkouranidou1, Maria Gkomini1, Eleni Karantzali1, Antonios-Periklis Panagiotopoulos1, Triantafyllos Alexiadis1, Stavroula Veletza2, Grigorios Tripsianis3, Maria Lambropoulou1 Laboratories of 1Histology-Embryology, 2Medical Biology and 3Medical Statistics, Department of Medicine, University of Thrace, Alexandroupolis

P156 Inhibition of complement-coagulation system cross talk attenuates cardiac tissue injury in an ARVC animal model Konstantinos Tsilafakis1, Ioanna Kostavasili1, Aimilia Varela2, Fani Pantouli1, Constantinos H. Davos2, Manolis Mavroidis1* 1

Center of Basic Research & 2Center of Clinical Research & Experimental Surgery, Biomedical Research Foundation, Academy of Athens

P157 Next generation sequencing panel for the detection of F12 mutations in patients with hereditary angioedema Sofia Vatsiou1,2, Gedeon Loules1, Maria Zamanakou1, Faidra Parsopoulou1,2, Fotis Psarros3, Dorottya Csuka4, Grzegorz Porebski5, Dumitru Moldovan6, Markus Magerl7, Marcus Maurer7, Matthaios Speletas2, Henriette Farkas4, Anastasios E. Germenis1,2.

CeMIA SA, Larissa; 2Department of Immunology & Histocompatibility, Faculty of Medicine, University of Thessaly, Larissa; 3Department of Allergology, Navy Hospital, Athens; Hungarian Angioedema Center, 3rd Department of Internal Medicine, Budapest; 5Department of Clinical and Environmental Allergology, Jagiellonian University Medical College, Poland; 6University of Medicine and Pharmacy, Romania; 7Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin 1 4

P158 Unraveling the metabolomic profiles of post-partum depression Zoe Papadopoulou1, Angeliki-Maria Vlaikou2, Georgia Chalkiadaki3, Marina Vafeiadi3, Katerina Margetaki3, Lida Chatzi3, Chris W. Turck4, Marika Syrrou1, Michaela D. Filiou2*

Laboratory of Biology, Medical Faculty & 2Laboratory of Biochemistry, Department of Biological Applications and Technology, University of Ioannina; 3Division of Social Medicine, Medical Faculty, University of Crete, Heraklion; 4Proteomics and Biomarkers, Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Germany 1

P159 The oncogene kdm2b regulates actin cytoskeleton signaling and motility in cancer cells Nefeli Zacharopoulou, Anna Tsapara, Galatea Kallergi, Sotirios C. Kampranis, Christos Stournaras* Department of Biochemistry, School of Medicine, University of Crete, Heraklion

11. Structure and Function of Macromolecules P160-P190 P160 NMR insights into the activation of soluble guanylate cyclase (sGC) by chemical compounds Aikaterini I. Argyriou1, Garyfallia I. Makrynitsa1, Aggeliki Roumana1, Minos-Timotheos Matsoukas1, Stavros Topouzis2* Department of Pharmacy & 2Department of Pharmacy, Laboratory of Molecular Pharmacology, University of Patras

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P161 Biochemical Properties of the circadian deadenylase AtHESPERIN Rafailia A.A. Beta1, Athanasios Kyritsis1, Veroniki Douka1, Vassiliki T. Skamnaki1, Dimitrios Vlachakis2, Demetres D. Leonidas1, Nikos Balatsos1* 1

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 2Genetics Laboratory, Department of Biotechnology, Agricultural University of Athens

P162 NMR conformational dynamics of LAM, RRM1 and RRM2 domains of La protein Georgios Bouras1, Aikaterini I. Argyriou1, Maria Apostolidi2, Eleni Kaliatsi2, Detlef Bentrop3, Constantinos Stathopoulos2, Georgios A. Spyroulias1* 1

Department of Pharmacy & 2Department of Biochemistry, School of Medicine, University of Patras; 3Institute of Physiology II, University of Freiburg

P163 Crystal structures of Ru(II) and Ru(III) complexes with model proteins Lykourgos Chiniadis1,2, Petros Giastas2, Ioannis Bratsos2, Athanasios Papakyriakou*2 Department of Biotechnology, Agricultural University of Athens; 2NCSR “Demokritos”, Athens

P164 Glycogen phosphorylase as a model for high-throughput crystallography (HTC). Christina E. Drakou1, Vasiliki Adamou-Androulaki1, George A. Stravodimos1, Anastasia L. Kantsadi2, Demetres D. Leonidas1, Vassiliki T. Skamnaki1* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa; 2Department of Biochemistry, University of Oxford

P165 NMR study of the Heme-Nitric Oxide/Oxygen Binding (H-NOX) domain from Νostoc sp, a homologue of soluble Guanylate Cyclase (sGC) Dimitra A. Georgopoulou1, Aikaterini I. Argyriou1, Garyfallia I. Makrynitsa1, Aikaterini A. Zompra1, Stavros Topouzis1, Andreas Papapetropoulos1,2, Georgios A. Spyroulias1* Department of Pharmacy, University of Patras; 2Faculty of Pharmacy, University of Athens

P166 Crystallization and modelling studies of a GH1 family 6-P-β-glucosidase from Geobacillus sp. SP24 discovered at Santorini Volcanic area Pandora F. Karakousi1,2,, Magda S. Chegkazi1,3, Anastasia P. Galanopoulou2, Dimitris G. Hatzinikolaou2, Evangelia D. Chrysina1,* Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens; 2Department of Biology, University of Athens; 3current address: King’s College London 1

P167 ABSTRACT WITHDRAWN P168 XRF mapping and Fe-K-edge μ-XAFS characterization of human nails Maria Katsikini1*, Ekaterini Mavromati1, Fani Pinakidou1, Eleni C. Paloura1, Katerina Manika2, Despina Papakosta2 1

School of Physics & 2Pulmonary Department, University of Thessaloniki

P169 Zn K edge EXAFS study of human nails Maria Katsikini1*, Ekaterini Mavromati1, Fani Pinakidou1, Eleni C. Paloura1, Dimitrios Gioulekas2† 1

School of Physics & 2Medical School, University of Thessaloniki

P170 Purification and crystallization of potato α-Glucan Phosphorylase Symeon M. Koulas, Efthimios Kyriakis, Theodora G.A. Solovou, George A. Stravodimos, Vassiliki T. Skamnaki, Demetres D. Leonidas* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa

P171 Structure-based inhibitor design studies targeting human liver Glycogen Phosphorylase Efthimios Kyriakis, Theodora G.A. Solovou, Olga S. E. Papaioannou, Symeon M. Koulas, Anastasia S. Tsagkarakou, George A. Stravodimos, Vassiliki T. Skamnaki, Demetres D. Leonidas* Department of Biochemistry & Biotechnology, University of Thessaly, Larissa

P172 Novel method for optimizing the expression of protein coding genes via random mutagenesis Aristeidis Ntoukas, Foteini Fotopoulou, Evangelia Konstantinou, Athanasios Drosos, Panagiota Perari, Athanasios Niarchos*, Konstantinos Poulas* Department of Pharmacy, University of Patras

P173 Studies on the role of the C-terminal segment of human Angiogenin in defining biological efficiency Olga S. E. Papaioannou, Myrto S. Patraskaki, Efthimios Kyriakis, Theodora G.A. Solovou, George A. Stravodimos, Georgios E. Papadopoulos, Demetres D. Leonidas* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P174 Cloning, expression and purification studies of the Odorant Binding Protein 7 from the malaria mosquito Anopheles stephensi Christos N. Petroulias1,2, Panagiota G.V. Liggri1,2, Katerina E. Tsitsanou1, Spyros E. Zographos1*

Institute of biology, medicinal chemistry & biotechnology, National Hellenic Research Foundation, Athens; 2Department of Biochemistry & Biotechnology, University of Thessaly, Larissa 1

P175 Expression purification and biophysical characterization of recombinant polypeptides of hepatitis E macro domain (HEV1) Maria D. Politi1, Georgios Bouras1, Fotis Papadopoulos2, Maria Birkou1, Dioni Dodi1, Konstantinos D. Marousis1, Bruno Coutard3, Georgios A. Spyroulias1 1

Department of Pharmacy, University of Patras; 2Arsakeia-Tositseia Schools, Patra; 3AFMB, UMR 7257 CNRS/ University of Merseille

P176 Peptide Inhibitors of B-Raf Kinase block dimerization and overcome paradoxical MEK/ERK activation Magdalini Rovoli1*, Chad Beneker2, Katerina E. Tsitsanou3, Spyros E. Zographos3, Campbell McInnes2, George Kontopidis1 1 3

Department of Biochemistry, Veterinary Faculty, University of Thessaly, Karditsa; 2Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, Columbia; Institute of Biological Research and Biotechnology, The National Hellenic Research Foundation, Athens

P177 Unravelling the structure-activity relationship of Lj-GSK3b, a ‘green’ GSK kinase Theodora G.A. Solovou, Efthimios Kyriakis, Olga S. E. Papaioannou, George A. Stravodimos, Constantine Garagounis, Kalliope K. Papadopoulou, Demetres D. Leonidas* University of Thessaly, Department of Biochemistry & Biotechnology, Larissa

P178 Conformational responses to pH of human insulin co-crystallized with ascorbic acid Maria Spiliopoulou1*, Paraskevi Kontou1, Alexandros Valmas1, Gerd Schluckebier2, Andrew N. Fitch3, Matthew Bowler4,5, Detlef Beckers6, Fotini Karavassili1, Irene Margiolaki1

Department of Biology, Section of Genetics, Cell Biology and Development, University of Patras; 2Diabetes Protein Engineering, Novo Nordisk, Malov, Denmark; 3European Synchrotron Radiation Facility, France; 4European Molecular Biology Laboratory, France; 5Unit for Virus–Host Cell Interactions, France; 6Malvern PANalytical B.V, Netherlands

P179 Expression, purification and NMR study of the 124-residues C-terminal polypeptide of Arkadia Maria Birkou, Konstantinos D. Marousis, Aikaterini A. Zompra, Georgios A. Spyroulias* Department of Pharmacy, University of Patras

P180 Human polyreactive monoclonal IgGs penetrate neoplastic cells, inhibit cell migration and induce apoptosis Theodora Stivarou, Ioannis Sarrigeorgiou, Petros Chalas, Anastasia Sopaki-Valalaki, Peggy Lymberi* Immunology Laboratory, Immunology Dept, Hellenic Pasteur Institute, Athens

P181 Rational mutagenesis to enhance solubility of N’-terminal domain (PHKA140-400) of alpha regulatory subunit of PhK. Eleni Politi#, Anastasia S. Tsagkarakou#, Theodora G.A. Solovou, George Stravodimos, George Papadopoulos, Demetres D. Leonidas, Vassiliki T. Skamnaki*. Department of Biochemistry and Biotechnology, University of Thessaly, Larissa.

P182 Analysis of intrinsically disordered regions of human transcription factor ZNF217. Dimitra Tsakona, Nikolaos Papanikolaou*

Department of Biology & Department of Medicine, University of Thessaloniki

P183 Expression, purification and NMR study of the macro2 domain of human PARP9 (PolyADP-Ribose Polymerase 9) with ADP-r Sofia-Antigoni Tsatsouli, Aikaterini C. Tsika, Georgios A. Spyroulias* Department of Pharmacy, University of Patras

P184 Identification and molecular characterization of novel transcripts of human L-DOPA decarboxylase (DDC) gene in human cancer cells, using next-generation sequencing approaches. Panagiotis Tsiakanikas, Panagiotis G. Adamopoulos, Christos K. Kontos, Aristeidis Panagiotou, Dido Vassilacopoulou, Andreas Scorilas* Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens

www.eebmb-congress.gr

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

P185 Revealing desmin head domain interactions with mitochondrial and lysosomal proteins: implications in cardiomyopathy Konstantinos Tsilafakis1, Dimitrios Vlachakis2, Ioanna Kostavasili1, Yassemi Capetanaki1, Sofia Kossida3, Manolis Mavroidis1* Center of Basic Research, Biomedical Research Foundation, Academy of Athens; Genetics Laboratory, Department of Biotechnology, Agricultural University of Athens; 3 IGH, CNRS, University of Montpellier, France 1 2

P186 Unraveling the structural characteristics of the C-terminal regions of Geminin family proteins Danai-Kalliopi Moschidi1, Aikaterini C. Tsika1, Marina Arbi2, Stavros Taraviras3*, Zoi Lygerou2*, Georgios A. Spyroulias1* Departments of 1Pharmacy, 2Physiology & 3General Biology, School of Medicine, Patras University

P187 ABSTRACT WITHDRAWN P188 Generation and characterization of a novel Fc-fusion Interferon lambda 2 analog Stelios Vlachiotis, Athanasios Stavropoulos, Ioanna Galani, Evangelos Andreakos Biomedical Research Foundation Academy of Athens

P189 Functional Structural and Toxicological characterisation of novel surface- acting agents from marine bacterial strains Styliani Chasapi1, Aikaterini A. Zompra1, Karina Salek2, Theodora Mantso3, Georgia-Persephoni Voulgaridou4, Ioannis Anestopoulos4, Tony Gutierrez2, Alexis Galanis4, Aglaia Pappa4, Mihalis Panagiotidis3, Stephen R. Euston2, Georgios A. Spyroulias1*

Department of Pharmacy, University of Patras; 2School of Engineering & Physical Sciences, Heriot Watt University, Edinburgh; 3Department of Applied Sciences, Northumbria University, Newcastle Upon Tyne; 4Department of Molecular Biology & Genetics, University of Thrace, Alexandroupolis 1

P190 The anti-cancer effect of Bromo-amine T (BAT) Stella Baliou1*, Markus Nagl2, Antony M. Kyriakopoulos3, Vassilis Zoumpourlis1*

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens; 2Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Austria; 3NASCO AD Biotechnology Laboratory, Pireas 1

12. Biotechnology of Plants and Micro-organisms P191-P200 P191 Development of a high-efficiency hairy root transformation method for the medicinal plant Trigonella foenum-graecum Konstantina Beritza, Maria-Eleni Georgopoulou, Constantine Garagounis, Kalliope K. Papadopoulou Laboratory of Plant and Environmental Biotechnology, Department of Biochemistry and Biotechnology, University of Thessaly, Larissa

P192 Textile dye bioremediation potential of some rhizobial strains and their heavy-metal and high salinity tolerance Rodica Cﾄフﾄネina Efrose, Catalina Stedel, Craita Maria Rosu*

Department of Experimental and Applied Biology, NIRDBS - Institute of Biological Research Iasi, Romania

P193 A Shaggy-like kinase (LSK1) mediates nodulation and nitrate response signals in Lotus japonicus Constantine Garagounis, Daniela Tsikou, Panagiota K. Plitsi, Ioanna S. Psarrakou, Marianna Avramidou, Marili Anagnostou, Maria-Eleni Georgopoulou, Kalliope K. Papadopoulou* Department of Biochemistry and Biotechnology, University of Thessaly, Larissa

P194 Bacterial and plant purine transport and metabolism are transcriptionally reprogrammed during symbiotic nitrogen fixation Chrysanthi Kalloniati1, Fotios Komaitis1, Dimitrios Skliros1, Maria-Eleftheria Zografaki1, Aikaterini Koletti2, Rodica Cﾄフﾄネina Efrose3, Emmanouil Flemetakis1*

Department of Biotechnology, Agricultural University of Athens; 2Department of Biology, University of Athens; 3Institute of Biological Research, Department of Experimental and Applied Biology, Romania 1

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

P195 The metabolite profile of M. truncatula is altered during symbiotic nitrogen fixation Chrysanthi Kalloniati1, Vassilios Iliopoulos2, Aikaterini Koletti3, Maria-Eleftheria Zografaki1, Fotios Komaitis1, Dimitrios Skliros1, Rodica Cătălina Efrose4, Serko Haroutounian2, Emmanouil Flemetakis1*

Department of Biotechnology & 2Department of Animal Science and Aquaculture, Agricultural University of Athens; 3Department of Biology, University of Athens; 4Institute of Biological Research, Department of Experimental and Applied Biology, Romania 1

P196 Profile of metabolites of Medicago truncatula under carbon starvation conditions Fotios Komaitis, Katerina Kalliampakou, Chrysanthi Kalloniati, Ioanna Anastasiou, Maria Patelou, Dimitrios Skliros, Emmanouil Flemetakis* Laboratory of Molecular Biology, Department of Biotechnology, Agricultural University of Athens

P197 Induction of defence responses against powdery mildew in zucchini by natural plant extracts of Reynoutria sachalinensis Theoni Margaritopoulou, Dimosthenis Kizis, Aimilia Markellou*

Benaki Phytopathological institute, Department of Phytopathology, Laboratory of Mycology, Greece

P198 SuptoxD2.0 – Αn engineered Escherichia coli strain that enables recombinant production of membrane proteins at high yields Myrsini Michou1,2, Dimitra Gialama1, Angelos Stergios1,2, Georgios Skretas1*

Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens; 2Department of Biochemistry & Biotechnology, University of Thessaly, Larissa 1

P199 The hpaB gene from Xanthomonas campestris pv. vesicatoria enhances abiotic stress tolerance in transgenic N. benthamiana Nikoletta Mitsopoulou1, Georgia I. Kelaidi2, George N. Skaracis2, Ourania I. Pavli1* 1

University of Thessaly, Volos; 2 Agricultural University of Athens

P200 Interaction between rhizobia and arbuscular mycorrhizal fungi during the establishment of symbioses in legume roots Daniela Tsikou1, Myrto Tsiknia2, Christina N. Nikolaou2, Kalliope K. Papadopoulou1, Constantinos Ehaliotis2 1

University of Thessaly, Larissa; 2Agricultural University of Athens

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Ευρετήριο | Index

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology November 23-25, 2018 Imperial Hotel, Larissa

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Avdoula, Eleni �� 35 Avgeris, Margaritis ��34, 37 Avgoulas, Dimitrios �� 30 Avramidis, Nikos �� 29 Avramidou, Marianna �� 41

Abel, Nikolaj B. �� 19 Adamopoulos, Panagiotis G. ��32, 40 Adamou-Androulaki, Vasiliki �� 39 Adam, Panagiotis �� 35 Admon, Arie �� 31 Afaloniati, Hara �� 34 Afendra, Amalia-Sofia �� 38 Agakidis, Charalampos �� 29 Agathangelidis, Andreas �� 14 Aidinis, Vassillis �� 34 Ainali, Chrysanthi �� 10 Aindelis, Georgios �� 35 Aivaliotis, Michalis ��10, 25, 27, 29, 32 Akrivou, Melpomeni G. �� 33 Aktypi, Andriana �� 11 Aletras, Alexios ��25, 26 Alexiadis, Triantafyllos �� 38 Ali, Bassam R. �� 35 Aliferis, Konstantinos A. �� 29 Alvarez, Luis �� 14 Amoutzias, Grigoris D. ��7, 19, 29 Anagnostopoulos, Achilles �� 14 Anagnostopoulos, Athanasios K. �� 12, 30, 31 Anagnostou, Marili �� 41 Anastasakis, Dimitrios �� 33 Anastasiadou, Ema �� 11, 14, 36 Anastasiou, Ioanna ��33, 42 Anderson, Ross �� 12 Andreakos, Evangelos �� 41 Andriopoulou, Christina �� 34 Andronidou, Elisavet Μ. �� 29 Anestopoulos, Ioannis �� 41 Angeli-Terzidou, Antonia-Eugenia �� 30 Angelopoulou, Katerina �� 34 Angelopoulou, Maria �� 26 Antonopoulos, Dionysios �� 32 Apostolidi, Maria ��16, 39 Apostolou, Aliki-Ioanna ��25, 26 Appendino, Giovanni �� 25 Arampatzi, Antonia �� 36 Arapatzi, Christina ��34, 37 Arbi, Marina ��26, 27, 28, 34, 41 Argitis, Panagiotis �� 28 Argyriou, Aikaterini I. �� 32, 38, 39 Artemaki, Pinelopi I. �� 32 Arvanitis, Dimitrios �� 27 Arvanitis, Nikolaos �� 27 Asimakoula, Matina �� 19 Audibert, Sylvain �� 31 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018

Badounas, F. �� 24 Badra, Nibal �� 34 Bagli, Eleni ��24, 26 Bagos, Pantelis G. �� 29 Balasopoulou, Angeliki �� 35 Balatsos, Nikos �� 3, 16, 32, 39 Balgkouranidou, Ioanna ��37, 38 Baliou, Stella �� 41 Barbayianni, Iliana �� 34 Barbera, C. �� 26 Barnea, Eilon �� 31 Batistatou, Anna �� 36 Batzali, Panagiota �� 37 Beckers, Detlef �� 18 Befani, Christina �� 25 Begou, Olga �� 29 Bellou, Eirini �� 28 Bellou, Sofia �� 26 Beneker, Chad �� 40 Benes, Vladimir �� 36 Beninatto, R. �� 26 Bentrop, Detlef ��19, 39 Beritza, Konstantina �� 41 Beta, Rafailia A.A. ��32, 39 Bettencourt-Dias, Monica �� 27 Bhasin, Hemal �� 19 Bianchi, Nicoletta �� 35 Birkou, Maria �� 40 Bonhomme, Céline �� 31 Borbolis, Fivos ��25, 33 Bougas, Anthony �� 18 Bouras, Georgios ��39, 40 Bouris, Panagiotis �� 15 Bourkoula, Athanasia �� 28 Bournaka, Spyridoula �� 28 Boutati, Eleni �� 34 Bowden, Thomas A. �� 14 Bowler, Matthew �� 40 Braliou, Georgia G. �� 29 Bratsos, Ioannis �� 39 Bravou, Vasiliki �� 15 Brézillon, Stéphane �� 11 Broderick, Ronan �� 29 46

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Canard, Bruno �� 19 Capetanaki, Yassemi ��37, 41 Carol, Murphy �� 24 Castanas, Elias �� 11, 27, 28 Celie, Patrick �� 12 Chachami, Georgia ��3, 11, 33 Chalas, Petros �� 40 Chalatsa, Ioanna �� 27 Chalikiopoulou, Constantina �� 35 Chalkiadaki, Georgia �� 38 Champeris Tsaniras, Spyridon �� 15 Charisiou, Sofia �� 36 Charizopoulou, Ioulia �� 11 Charonis, Aristidis S. �� 37 Chartoumpekis, Dionysios �� 37 Chasapi, Styliani �� 41 Chasapi, Styliani A. �� 29 Chatziioannou, Aristotelis �� 30 Chatzi, Lida �� 38 Chatzopoulos, Athanasios �� 38 Chatzouli, Aikaterini �� 35 Chavrier, Philippe �� 26 Chegkazi, Magda S. �� 39 Cheimonidi, Maria-Christina ��15, 32 Cheng, Caixia �� 30 Cherdyntseva, Veronica �� 29 Chevet, Eric �� 30 Chiniadis, Lykourgos �� 39 Chira, Panayiota �� 26 Chlichlia, Katerina �� 35 Choleva, Efrossyni �� 25 Choli-Papadopoulou, Theodora ��24, 33 Christodoulou, Maria-Ioanna �� 34 Christoforidis, Savvas �� 25, 26, 38 Christoforou, Marilena �� 34 Christophides, George �� 7, 17 Christopoulou, Maria-Elpida ��25, 26 Christou, Soteroula �� 35 Chroni, Angeliki �� 14 Chrousos, George �� 35 Chrysina, Evangelia D. �� 39 Constantinidou, Nikki �� 35 Coomer, Charles �� 14 Cosenza, Lucia Carmela �� 35 Cournia, Zoe �� 26 Coutard, Bruno ��19, 40 Csuka, Dorottya �� 38

Dadami, Elena �� 16 Dafnis, Ioannis �� 14 Dafou, Dimitra ��10, 34 Dalakoura – Karagkouni, Katerina �� 34 Dalakouras, Athanasios �� 16 Danalatos, Iosif Rodolfos �� 15, 24, 34 Daniilidis, Aggelos �� 24 Daskalaki, Maria G. �� 33, 35, 36 Davos, Constantinos H. �� 38 Deda, Olga �� 29 Degen, Thomas �� 18 Dempsey, Nora M. �� 10 Dermoniotis, David �� 33 de Weijert, Mirjam �� 15 Diamanti, Christina �� 36 Diamantopoulos, Marios A. �� 32 Didaskalou, Stelios �� 27 Dimas, Konstantinos �� 32 Dimitrakopoulou-Strauss, Antonia �� 30 Dinos, George P. �� 18 Diseri, Aikaterini �� 33 Dodi, Dioni �� 40 Douka, Veroniki �� 39 Doultsinos, Dimitrios �� 30 Douni, Eleni ��27, 29 Douvas, Antonios M. �� 28 Drakos, Elias ��27, 32 Drakou, Christina E. ��18, 39 Drakouli, Sotiria �� 28 Drekolias, Dimitrios �� 12 Driquez, Benjamin �� 10 Drosos, Athanasios ��30, 39 Dumas-Bouchiat, Frédéric �� 10 du Preez, Robin �� 12

Economides, Aris �� 16 Efrose, Rodica Cătălina ��41, 42 Efstathiou, Christos �� 27 Efstathiou, Georgios �� 36 Efstathiou, Nikolaos �� 29 Efstratiadis, Argiris �� 36 Efstratiou, Ioannis �� 37 Ehaliotis, Constantinos �� 42 Euston, Stephen R. �� 41 Evangelou, Konstantinos �� 36 Evmorfopoulou, Theodora �� 29

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Gerontidi, Dimitra �� 37 Giagkas, Giorgos �� 35 Giakountis, Antonis �� 16 Gialama, Dimitra �� 42 Giannakouros, Thomas �� 10 Giannakou, Urania �� 37 Gianniou, Despoina D. �� 32 Giannou, Anastassios D �� 15 Giarimoglou, Nikoleta �� 16 Giassafaki, Lefki-Pavlina �� 10 Giastas, Petros ��18, 39 Giatromanolaki, Alexandra ��16, 36 Gika, Helen �� 29 Gioulekas, Dimitrios �� 39 Giourieva, Veronica �� 27 Gkeka, Despoina ��25, 38 Gkelis, Spyros �� 28 Gkikopoulou, Evi �� 27 Gkoliou, Glykeria �� 35 Gkomini, Maria ��37, 38 Gkotinakou, Ioanna-Maria ��25, 33 Glarou, Meropi �� 26 Goette, Martin �� 27 Gorgogietas, Vyron �� 26 Gorgoulis, Vassilis G. �� 15, 26, 36 Goula, Evangeli �� 25 Goumenos, Dimitrios S. �� 29 Gounari, Eleni �� 24 Gounari, Maria �� 14 Gourgoulianis, Konstantinos I. �� 28, 29, 32 Goutas, Andreas �� 24 Grafanaki, Katerina �� 33 Grammatikaki, Stefania �� 24 Gravanis, Achille �� 37 Gregoriou, Maria-Eleni �� 31 Greve, Burkhard �� 27 Gutierrez, Tony �� 41

Falidas, Evangelos �� 35 Fanis, Pavlos �� 35 Fanitsios, Chris �� 19 Farge, Emmanuel �� 10 Farkas, Henriette ��37, 38 Fatouros, Dimitrios �� 10 Feidantsis, Konstantinos �� 37 Fessas, Dimitrios �� 18 Filiou, Michaela D. ��14, 38 Filippa, Vicky ��11, 14 Fili, Stavroula �� 18 Fish, Alex �� 12 Fitch, Andrew N. ��18, 40 Flemetakis, Emmanouil �� 33, 41, 42 Fotopoulou, Foteini �� 39 Fotsis, T. �� 24, 26, 36 Fragkoulis, Charalampos �� 12 Fragoulis, Emmanuel G. �� 34 Franchi, M. ��11, 26 Frillingos, Stathis �� 19

Gagos, Sarantis �� 29 Galani, Ioanna �� 41 Galanis, Alexis �� 12, 29, 30, 41 Galanopoulou, Anastasia P. �� 39 Galaris, Apostolos �� 34 GALAXY consortium �� 14 Galesso, D. �� 26 Galigalidou, Chrysi �� 14 Galliou, Panagiota Angeliki �� 29 Galtsidis, Sotirios �� 11 Gambari, Roberto �� 35 Garagounis, Constantine �� 26, 40, 41 Gardikis, Kostantinos �� 33 Gargani, Sofia �� 16 Gemenetzi, Katerina �� 14 Georgantopoulos, Achilleas �� 26 Georgatos, Spyros �� 8, 17 Georgatsou, Eleni ��3, 10, 28 Georgiadis, Dimitris �� 31 Georgiou, Stella �� 11, 14, 36 Georgopoulou, Dimitra A. �� 39 Georgopoulou, Maria-Eleni �� 41 Georgoulis, Anastasios �� 35 Gerakoudis, Konstantinos D. ��26, 35 Gerasimatou, Fotini �� 35 Germenis, Anastasios E. ��37, 38 Geromichalos, Georgios �� 30 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018

Habeos, Ioannis �� 37 Hadjipavlou-Litina, Dimitra �� 35 Hadzidimitriou, Anastasia �� 14 Halevas, Eleftherios ��30, 31 Hardas, Alexander �� 10 Haroutounian, Serko �� 42 Hatzigeorgiou, Artemis �� 36 Hatziloukas, Efstathios �� 38 Hatzinikolaou, Dimitris G. �� 39 Hatzivassiliou, Eudoxia G. ��10, 26 Hatzoglou, Chrissi ��28, 29 48

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

Hatzopoulos, Polydefkis �� 19 Hayes, Joseph M. �� 26 Heldin, Paraskevi �� 38 Holt, Dennis B. �� 19

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Kanellou, Alexandra �� 11 Kantsadi, Anastasia L. ��18, 39 Kaplani, Konstantina �� 26 Karaboga, A. �� 26 Karagiannis, George S. �� 34 Karagiota, Angeliki �� 33 Karagkiaouri, Maria �� 31 Karagkouni, Evdokia C. �� 29 Karakaidos, Panos �� 15 Karakasiliotis, Ioannis ��31, 35 Karakota, Maria �� 24 Karakousi, Pandora F. �� 39 Karalis, Theodoros �� 38 Karamani, Maria �� 25 Karamani, Valia �� 26 Karamanos, Nikos �� 3, 4, 13, 15, 17, 26, 27, 28, 36, 38 Karamanou, Konstantina �� 11 Karamitros, Timokratis �� 36 Karampatakis, Vasileios �� 24 Karantoni, Chara �� 32 Karantzali, Eleni �� 38 Karatzas, Demetrios N. �� 26 Karavanis, Emmanouel �� 34 Karavassili, Fotini ��18, 40 Karayiannis, Yiannis ��35, 36 Kardasis, D. �� 3 Kardassis, Dimitris ��16, 34 Karioti, Anastasia �� 34 Karkabounas, Athanassios �� 19 Karkavitsa, Anna-Aspasia �� 32 Karolidis, George �� 24 Karoulias, Stylianos Zafeirios ��24, 33 Karousi, Foteini �� 15 Karra, Aikaterini G. ��25, 26 Kartsiouka, Chrysoula �� 36 Kasselimi, Eirini ��27, 36 Kastana, Pinelopi �� 25 Katopodi, Vicky �� 33 Katsafadou, Angeliki I. �� 31 Katsani, Katerina ��8, 11, 31 Katsantoni, Eleni �� 35 Katsara, Klytaimnistra �� 27 Katsaros, Stilianos �� 37 Katsiari, Christina G. �� 36 Katsikini, Maria �� 39 Katsila, Theodora �� 35 Katsioulas, Christos �� 33 Katsipis, Georgios ��30, 31 Kazeli, Konstantina �� 31 Kechagia, Eleni �� 30

Iatrou, Kostas �� 18 Ieronymaki, Eleftheria �� 33, 35, 36 Iliadou, Marianna �� 24 Iliopoulos, Othon �� 8, 15 Iliopoulos, Vassilios �� 42 Iliopoulou, Maro �� 14 Ioakeimidis, Fotis �� 16 Ioannidis, Konstantinos �� 24 Ioannou, Maria ��35, 37 Isik-Andrikopoulos, Gozde �� 30

Jagirdar, Rajesh M. ��28, 29 Jakobsdottir, Maria �� 14 Jansen, Kees �� 15 John, Anne �� 35

Kafetzopoulou, Kanela �� 34 Kakabakos, Sotirios E. �� 28 Kakouratos, Christos �� 36 Kalaidzidis, Yannis �� 25 Kalantidou, Aikaterini �� 32 Kalantzis, Evangelos �� 27 Kalavrizioti, Dimitra �� 29 Kalavros, Nikolas �� 36 Kaliatsi, Eleni �� 16, 32, 39 Kalioraki, Maria-Anna �� 15 Kallergi, Galatea �� 38 Kalliampakou, Katerina �� 42 Kalloniati, Chrysanthi ��41, 42 Kalofonos, Haralabos P. ��15, 38 Kalogeropoulou, Argyro �� 24 Kalousi, Alkmini �� 31 Kalousi, Foteini D. ��25, 26 Kalyvianaki, Konstantina ��11, 27 Kaminari, Archontia �� 30 Kamouza, Evdoxia �� 32 Kampa, Marilena �� 11, 27, 28 Kampolis, Dimitrios �� 35 Kampouridis, Georgios �� 35 Kampranis, Sotirios C. �� 38 Kanariou, Maria �� 35 Kanata, Eirini �� 34 49

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Kefali, Elena �� 27 Kelaidi, Georgia I. �� 42 Keramidiotou, Athina �� 25 Kesesidis, Nikolaos �� 38 Kesisova, Ileana �� 11 Kesisova, Ilona �� 27 Kikidou, Lena �� 24 Kintzios, Spyridon �� 29 Kirgou, Paraskevi �� 34 Kitsiouli, Eirini �� 35 Kizis, Dimosthenis �� 42 Kleanthous, Marina �� 35 Kletsas, Dimitris ��3, 15, 18, 24, 25, 26, 28, 36 Klinakis, Apostolos �� 15 Klippel, Sven �� 30 Kloukina, Ismini �� 11 Koczan, Dirk �� 30 Koffa, Margy �� 11, 27 Kokkala, Paraskevi �� 31 Kokkinopoulou, Ioanna K. �� 34 Kolettas, Evangelos �� 26, 34 Koletti, Aikaterini �� 41, 42 Koliakos, George ��24, 29, 36 Kollia, Panagoula �� 35, 36 Kolliniati, Ourania �� 35 Kolokotroni, Anthi �� 27 Komaitis, Fotios �� 41, 42 Konstandi, Maria �� 34 Konstantinou, Dimitrios �� 10 Konstantinou, Evangelia �� 39 Konstantinou, Maria �� 26 Kontizas, Eleftherios �� 35, 36 Kontonasaki, Eleana �� 31 Kontopidis, George �� 40 Kontopikou, Katerina �� 36 Kontopodis, Evangelos �� 12, 30 Kontos, Christos K. ��15, 32, 40 Kontou, Panagiota I. �� 29 Kontou, Paraskevi �� 18, 40 Kontoyiannis, Dimitris L. �� 16 Kordias, Dimitris �� 15, 33 Kordou, Zoi �� 25 Kormentza, Elisavet �� 36 Koromilas, Antonis �� 8, 14 Korovesi, Artemis G. �� 31 Kossida, Sofia �� 41 Kostavasili, Ioanna �� 38, 41 Kostopoulou, Nikoleta �� 24, 26 Kostourou, V. ��3 Kostourou, Vassiliki ��12, 34, 37 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018 Hotel Imperial, Λάρισα www.eebmb-congress.gr

Koudounas, Konstantinos �� 19 Kougioumtzi, Anastasia �� 36 Koukkou, Anna Irini �� 19 Kouklis, Panos �� 11 Koukoulas, Kreon �� 16 Koukoulis, George �� 35, 37 Koukourakis, Michael I. �� 16, 36 Koulas, Symeon M. �� 39 Kouliou, Olympia �� 28 Koumandou, Vassiliki Lila �� 12, 30 Koumantou, Despoina �� 31 Kouroumalis, Anastasios �� 25 Kouroupis, D. �� 24 Kourti, Maria �� 36 Koutras, Nikolaos �� 10 Koutroumani, Maria �� 10 Koutsandreas, A. �� 27 Krini, Maro �� 35 Kritikos, Kostas �� 27 Krokidis, Marios �� 18 Kryukova, Elena V. �� 18 Kyriakis, Efthimios ��18, 39, 40 Kyriakopoulos, Antony M. �� 41 Kyriakopoulos, George �� 33 Kyriakopoulou, Konstantina �� 27 Kyriakopoulou, Zaharoula �� 29 Kyriakou, Eleni �� 25 Kyritsis, Athanasios �� 32, 39 Kyritsis, Konstantinos A. �� 10, 33 Kyrkou, Athena ��24, 26, 36 Kyrousi, Christina �� 26 Kyrpides, Nikos �� 8, 12

Lafontaine, Denis �� 28 Lala, Maria �� 14, 36 Lalioti, Maria-Eleni �� 15, 26 Lambrianidou, Andromachi �� 32 Lambropoulou, Maria �� 37, 38 Lampadas, Dimitrios �� 26 Lamprianidou, Andromachi �� 28 Lamprou, Paraskevas �� 24, 33 Latosinska, Agnieszka �� 12 Lazani, Vasiliki �� 25 Lazou, Antigone �� 37 Le Denmat, Simon �� 10 Lederer, Carsten �� 35 Lekka, Maria Eleni �� 35 Leondaritis, George �� 34 Leonidas, Demetres D. �� 3, 13, 18, 39, 40 50

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

Leontiadou, Hari �� 26 Le Roy, Damien �� 10 Letsiou, Sophia �� 33 Liakopoulou, Ariadni �� 29 Liakos, Panagiotis �� 3, 15, 25, 33, 37 Liakou, Eleni �� 36 Lialiaris, Theodoros �� 31, 37 Liggri, Panagiota G.V. �� 18, 40 Liosi, Aikaterini-Anna �� 15, 32 Li, Shuang �� 16 Litsardakis, Georgios �� 30, 31 Litsiou, Stavroula �� 35 Livaniou, Evangelia �� 24 Logotheti, Souzana �� 18 Lokka, Georgia �� 26 Lotsi, Elisavet �� 25 Loules, Gedeon �� 37, 38 Lourou, Niki �� 16 Lygerou, Zoi ��10, 11, 15, 24, 26, 27, 28, 34, 36, 41 Lygirou, Vasiliki �� 12 Lykogianni, Maira �� 29 Lykoudi, Elisavet �� 33 Lymberi, Peggy �� 40 Lymperaki, Evgenia �� 31 Lyroni, Konstantina �� 35, 36

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Markellou, Aimilia �� 42 Markmann, Katharina �� 19 Markopoulos, George �� 26, 34 Markoulatos, Panayotis �� 29 Markou, Maria �� 24, 26 Maroudas, Alexandros �� 37 Marousis, Konstantinos D. �� 40 Martin-Esteban, Adrian �� 31 Martinez-Gonzalez, Beatriz �� 35 Mathiopoulos, Kostas �� 3, 12, 17, 31 Matsoukas, Minos-Timotheos �� 12, 38 Mattaj, Iain �� 7, 17 Matzarapi, Konstantina V. �� 29 Maurer, Marcus �� 38 Mavrikou, Sophia �� 29 Mavrogeorgis, Emmanouil �� 12 Mavrogonatou, Eleni �� 25, 26, 28, 36 Mavroidi, B. �� 31 Mavroidis, Manolis �� 38, 41 Mavromara, Penelope �� 31 Mavromati, Ekaterini �� 39 Maxouri, Styliani �� 36 McInnes, Campbell �� 40 Megalou, Evgenia �� 14 Melekis, Efstathios �� 19 Ménager, Christine �� 10 Mentis, Andreas �� 35, 36 Merceur, Mélanie �� 15 Methenitis, C. �� 31 Michaelidis, Theologos �� 33, 38 Michalopoulos, Ioannis �� 33 Michel, Aude �� 10 Michou, Myrsini �� 42 Miliotou, Androulla N. �� 14 Millar, Robert �� 12 Mimouli, Kalliopi �� 29 Mischak, Harald �� 12 Mitrakas, Achilleas �� 36 Mitrossilis, D. �� 10 Mitrou, Panagiota �� 34 Mitsis, Mihalis �� 35 Mitsopoulou, Nikoletta �� 42 Moldovan, Dumitru �� 37, 38 Morfos, Vasileios �� 10 Moschidi, Danai-Kalliopi �� 41 Mosialos, George ��10, 14, 26 Mossialos, G. ��3 Mougkogianni, Maria �� 24 Moulistanos, Aristotelis �� 36 Mountaki, Christina �� 14

Maben, Zachary �� 31 Madsen, Lene H. �� 19 Magdolen, Viktor �� 37 Magerl, Markus �� 37, 38 Magklara, Angeliki �� 15, 33 Makridakis, Manousos �� 12, 31 Makrynitsa, Garyfallia I. �� 38, 39 Malagon, Sandra Gonzalez �� 28 Malamidou, Angeliki �� 36 Malamos, Panagiotis �� 11, 27 Malatras, Apostolos �� 33 Maltabe, Violetta A. �� 11 Manika, Katerina �� 39 Manolis, Apostolos �� 30 Manou, Dimitra �� 15 Mantso, Theodora �� 41 Mantsou, Aglaia �� 24, 33 Marangos, Petros �� 28 Maratou, Eirini �� 34 Margaritopoulou, Theoni �� 42 Margetaki, Katerina �� 38 Margiolaki, Irene �� 18, 40 Marka, Sophia �� 29 51

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Mourati, Sofia �� 34 Moustafa, Savvina �� 31 Moustakas, A. ��3 Moustou, Eleni �� 27 Mpournaka, Spyridoula �� 28 Mullen, William �� 12 Müllertz, Anette �� 10 Murphy, Carol �� 26, 36 Mylonis, Ilias ��3, 14, 16, 28, 29, 33

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Pagkakis, Stamatis �� 11 Palaiologou, Vassiliki �� 26 Palioura, Dimitra �� 37 Paloura, Eleni C. �� 39 Panagiotaki, Katerina �� 30 Panagiotara, Angeliki �� 35 Panagiotidis, Christos A. �� 26, 35 Panagiotidis, Mihalis �� 41 Panagiotopoulos, Antonios-Periklis �� 38 Panagiotopoulos, Athanasios ��11, 27, 28 Panagiotou, Aristeidis �� 40 Panagiotou, Petros N. �� 36 Panagopoulos, Andreas �� 10, 11, 28, 34 Panayiotidis, Mihalis I. �� 16 Panayotou, George �� 26 Pangou, Εva �� 33 Pan, Leyun �� 30 Panoutsopoulou, Konstantina �� 37 Pantazaki, Anastasia �� 27, 30, 31, 36 Pantazopoulou, Vasiliki ��11, 14, 36 Pantelios, Alexandros �� 37 Panteris, Emmanuel �� 10, 28 Pantouli, Fani �� 38 Papadaki, Eirini �� 32 Papadaki, Eleni �� 36 Papadaki, Maria �� 27 Papadakis, Vassilis �� 27 Papadaki, Vasiliki �� 37 Papadatou, Vasiliki �� 37, 38 Papadimitriou, Evangelia �� 25 Papadodima, Olga �� 30 Papadopoulos, Angelos �� 26, 36 Papadopoulos, Charalampos �� 37 Papadopoulos, Fotis �� 40 Papadopoulos, George �� 3, 12, 30, 39, 40 Papadopoulos, M. �� 31 Papadopoulos, Stelios �� 35 Papadopoulou, Adamantia �� 36 Papadopoulou, Eleni �� 28 Papadopoulou, Kalliope �� 19 Papadopoulou, Kalliope K. ��3, 16, 19, 40, 41, 42 Papadopoulou, Kiriaki �� 31 Papadopoulou, Lefkothea C. �� 14 Papadopoulou, Maria-Despina �� 33 Papadopoulou, Zoe �� 38 Papafotika, Alexandra �� 26 Papagelopoulos, Panayiotis J. �� 25 Papageorgiou, Anna �� 35 Papageorgiou, Aristotelis �� 30

Nagl, Markus �� 41 Nakos, Konstantinos �� 11 Nanou, Aikaterini �� 35 Nastos, Dimitrios �� 35 Nathanaidilou, Patroula �� 36 Nénert, Gwilherm �� 18 Newton, Claire �� 12 Niaka, Konstantina �� 28 Niarchos, Athanasios �� 37, 39 Niavi, Christina �� 34 Niedzwiedz, Wojciech �� 29 Nieminuszczy, Jadwiga �� 29 Nika, Konstantina �� 10 Nikolaidis, Marios �� 29 Nikolakaki, Eleni �� 10 Nikolakopoulou, Konstantina �� 15 Nikolaou, Christina N. �� 42 Nikolaou, Panagiotis �� 27 Nikolopoulou, Evangelia �� 24 Nikolopoulou, Pinelopi �� 34, 37 Nikou, Sofia �� 15 Nikza, Polyxeni �� 31 Ninou, Ioanna �� 34 Nolan, Rory �� 14 Notas, George ��11, 27, 28 Ntafis, Vasileios �� 16 Ntallis, Sotirios G. �� 26, 35 Ntatsoulis, Konstantinos �� 37 Ntenekou, Despoina �� 25 Ntoukas, Aristeidis �� 30, 39 Ntoumas, Konstantinos �� 12

Oikonomidou, Eirini �� 36 Onisto, Maurizio �� 11 Orfanoudaki, Georgia �� 29 Osbourn, Anne �� 7, 19 Oulas, Anastasis �� 29 Ouzounidis, Vasileios- Rafail �� 26 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

Papageorgiou, Nicolas �� 19 Papageorgiou, Sotirios G. �� 32 Papaioannou, Maria �� 29 Papaioannou, Olga S. E. ��18, 39, 40 Papakosta, Despina �� 39 Papakostas, Georgios �� 19 Papakyriakou, Athanasios ��18, 31, 39 Papamichali, Roidoula �� 35 Papanagnou, Panagiota �� 30 Papanastasiou, Anastasios D. �� 15, 38 Papanikolaou, Nikolaos �� 24, 40 Papapetropoulos, Andreas �� 39 Papasakellariou, Konstantinos �� 30 Papassideri, Isidora S. �� 12 Papathanassiou, Maria �� 35, 37 Papathanos, Philippos A. �� 12 Papazoglou, E. �� 29 Papazoglou, Eleftherios D. �� 28 Papi, Rigini �� 27 Papoutsi, Androniki �� 37 Pappa, Aglaia �� 16, 41 Pappas, Anastasios �� 30 Pappas, Dimitris �� 28 Pappas, Ioannis S. �� 14 Pappas, Periklis �� 34 Pappa, Vasiliki �� 32 Pappi, Polyxeni �� 32 Paraskeva, Efrosyni �� 3, 11 Paravatou-Petsotas, M. �� 31 Parisot, Pascaline �� 28 Parlapani, Evangelia �� 26 Parra, Sergi Padilla �� 14 Parsopoulou, Faidra �� 37, 38 Paschou, Peristera ��12, 29, 30 Passi, Alberto �� 11 Patelou, Maria �� 42 Pateras, Ioannis S �� 15 Patmanidi, Alexandra L �� 15 Patraskaki, Myrto S. �� 39 Patrinos, George P. �� 35 Pavlidou, Eleni �� 10 Pavli, Ourania I. �� 42 Pavli, Pagona �� 28 Pazaitou-Panayiotou, Kalliopi �� 30 Pazarli, Elissavet �� 37 Pazidis, Angelos �� 35 Pelecanou, M. �� 31 Pentavra, Ch. �� 28 Perari, Panagiota �� 30, 39 Peroulis, Nikos �� 36

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Perrakis, Anastassis �� 12 Pervana, Stavroula �� 37 Petraki, Kalliopi �� 35 Petropoulos, Michalis ��15, 34, 36 Petropoulou, Christina �� 37 Petroulaki, Vassiliki �� 27, 28 Petroulias, Christos N. �� 40 Petrou, Panagiota S. �� 28 Phylactides, Marios �� 35 Pierros, Vasileios ��12, 30, 36 Pilalis, Eleftherios �� 30 Pinakidou, Fani �� 39 Piperigkou, Zoi �� 27, 28 Pirmettis, I. �� 31 Pitou, Maria �� 24 Plitsi, Panagiota K. �� 41 Podicheti, R. �� 29 Polikanov, Yury S. �� 18 Polioudaki, Hara �� 11, 28 Politi, Anna �� 32 Politi, Eleni �� 40 Politi, Maria D. �� 30, 40 Pongrac, Igor �� 11 Porebski, Grzegorz �� 37, 38 Poulaki, Smaragda �� 37 Poulas, Konstantinos �� 30, 39 Poulou, Eleni �� 18 Pouroutzidou, Georgia �� 31 Poutahidis, Theofilos �� 10, 34 Pratsinis, Harris ��24, 25, 26, 31, 36 Pritsa, Agathi �� 31 Psarra, Anna-Maria �� 3, 10, 25, 26 Psarra, Eleni �� 25 Psarrakou, Ioanna S. �� 41 Psarras, Stelios �� 37 Psarra, Theophano A. �� 34 Psarros, Fotis �� 37, 38 Psatha, Konstantina �� 10, 27, 29, 32 Pseftogas, Athanasios �� 10 Psomopoulos, Fotis �� 14

Raftopoulou, Christina �� 14, 29 Rallis, John �� 33 Ranno, Laurent �� 10 Rantala, Juha K. �� 34 Ranti, Dimitra �� 33 Ratcliffe, Sir Peter �� 13 Reczko, Martin �� 31 Reid, Dugald E. �� 19 53

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Reis-Filho, Jorge S. �� 15 Rigas, Stamatis �� 25 Rinotas, Vagelis �� 27 Riziotis, Ioannis �� 24 Rizou, Sophia �� 26, 36 Roma, Eleftheria �� 35 Röper, J.-C. �� 10 Rosenquist, Richard �� 14 Rosu, Craita Maria �� 41 Rouka, E. �� 29 Roukos, Vassilis �� 10 Roumana, Aggeliki �� 38 Rouni, Gina �� 37 Roupa, I. �� 31 Roupakia, Eugenia �� 34 Rovoli, Magdalini �� 40

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Siqueira, Scheyla �� 10 Sirinian, Chaido �� 15, 38 Skamnaki, Vassiliki T. �� 3, 18, 39, 40 Skamnelou, Margarita �� 27 Skandalis, Spyros S. �� 38 Skaracis, George N. �� 42 Skeparnias, Ilias �� 32, 33 Skeva, Katerina �� 36 Sklaviadis, Theodoros �� 34 Skliros, Dimitrios �� 41, 42 Sklirou, Aimilia D. �� 15, 32 Skretas, Georgios �� 42 Sokratous, Maria �� 36 Solovou, Theodora G.A. ��18, 39, 40 Sopaki-Valalaki, Anastasia �� 40 Soutoglou, Evi �� 31 Spanou, Kleopatra �� 35 Speletas, Matthaios �� 37, 38 Spella, Magda �� 38 Spiliopoulou, Maria �� 18, 40 Spyridopoulou, Katerina �� 35 Spyrou, George M. �� 29 Spyroulias, Georgios A. �� 8, 12, 18, 19, 29, 30, 32, 39, 40, 41 Stamatiou, Konstantinos �� 28 Stamatopoulos, Kostas �� 14 Stamatopoulou, Vassiliki �� 16, 28 Stathatos, Ilias �� 12 Stathopoulos, Constantinos �� 16, 32, 33, 39 Stathopoulos, Efstathios N. �� 27 Stathopoulos, George �� 15, 38 Stathopoulou, Konstantina �� 37 Stavropoulos, Athanasios �� 41 Stedel, Catalina �� 41 Stefanaki, Thalia �� 37 Steiropoulos, Paschalis �� 37 Stephanou, Coralea �� 35 Stergios, Angelos �� 42 Stergiou, Dimitra �� 32 Stern, Lawrence J. �� 31 Stivarou, Theodora �� 30, 40 Stougaard, Jens �� 19 Stournaras, Christos �� 38 Stratikos, Efstratios �� 31 Stravodimos, George A. ��18, 39, 40 Stravopodis, Dimitrios J. ��11, 12, 36 Stroggilos, Rafael �� 12 Stuart, David �� 7, 13 Sutton, Lesley-Ann �� 14 Svetlov, Maxim S. �� 18

Sachpekidis, Christos �� 30 Sagnou, M. �� 31 Salek, Karina �� 41 Salifoglou, Athanasios �� 30, 31 Samara, Diana �� 31 Samara, Maria �� 35, 37 Samiotaki, Martina �� 26, 38 Sandaltzopoulos, Raphael �� 14, 34 Santorinaiou, Anna �� 24 Sarafidis, Kosmas �� 29 Saridaki, Maria-Ioanna �� 16 Sarrigeorgiou, Ioannis �� 40 Savvidou, Olga D. �� 25 Schaapveld, Roel �� 15 Schalken, Jack �� 15 Schizas, Michael �� 38 Schluckebier, Gerd �� 40 Schultz, Iman �� 15 Scorilas, Andreas ��15, 32, 34, 37, 40 Sekerli, Eleni �� 36 Selenica, Pier �� 15 Sereti, Evangelia �� 32 Sexauer, Moritz �� 19 Sfikas, Evangelos �� 38 Sgouras, Dionyssios �� 3, 15, 35, 36 Shaukat, Athanasios-Nasir �� 32, 33 Shaw, Gorky �� 10 Siatra, Panagiota �� 27 Sideras, Paschalis �� 37 Sideratou, Zili �� 30 Sigala, Ioanna �� 10 Simos, George �� 3, 4, 13, 16, 17, 25, 29, 33 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

Symeonidou, Ioanna-Eleni �� 11 Synolaki, Eugenia �� 37 Syntichaki, Popi �� 25, 33 Syrrou, Marika �� 38

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

Tsatsouli, Sofia-Antigoni ��19, 30, 40 Tschari, Eleni �� 26 Tseleni-Balafouta, Sofia �� 11, 36 Tserou, Paraskevi �� 15 Tsetlin, Victor �� 18 Tsetsos, Fotis ��12, 29, 30 Tsiakanikas, Panagiotis �� 32, 40 Tsialtas, Ioannis �� 26 Tsifintaris, Margaritis ��12, 29, 30 Tsika, Aikaterini C. ��19, 40, 41 Tsiknia, Myrto �� 42 Tsikou, Daniela ��19, 41, 42 Tsilafakis, Konstantinos �� 38, 41 Tsimpidis, Michail �� 29 Tsiourvas, Dimitris �� 30 Tsitsanou, Katerina E. �� 18, 40 Tsochantaridis, Ilias �� 16 Tsoukni, Tatiana �� 34 Tsoumani, Konstantina �� 12, 31 Turck, Chris W. �� 38 T., Vassiliki �� 39 Tzardi, Maria �� 27 Tzartos, Socrates �� 18 Tzimagiorgis, Georgios �� 10 Tzortziou, Maria �� 26 Tzortzis, Efthymios �� 27 Tzouvelekis, Argyrios �� 34

Taouktsi, Eirini �� 25 Taraviras, Stavros ��10, 11, 15, 24, 26, 27, 28, 34, 36, 41 Tastsoglou, Spiros �� 36 Tatsaki, Ekaterini �� 19 Tavianatou, A.G. �� 26 Taze, Chrysa �� 28 Telligiannidou, Arretha �� 24 Tentes, Ioannis �� 37 Theocharidou, Anna �� 31 Theocharis, Achilleas �� 15 Theodoridis, Georgios �� 29 Theodoropoulos, Panayiotis �� 11, 28 Theodorou, Georgios �� 31 Thomopoulou, Margarita �� 19 Thymiakou, Efstathia �� 16 Tiniakou, Ioanna �� 34 Tokamani, Maria �� 34 Tologkos, Stylianos �� 37, 38 Topali, Stavroula �� 12 Topouzis, Stavros �� 38, 39 Torbantoni, Efthimia �� 31 Toufaki, Vasiliki �� 36 Touloumi, Katerina �� 34 Toumpeki, Chrisavgi �� 35 Trachana, Varvara �� 24 Trampari, Sofia �� 18 Trangas, Theoni �� 32 Trigazis, Efstathios �� 25 Tripsianis, Grigorios �� 37, 38 Trougakos, Ioannis P. �� 15, 32 Tsagkarakou, Anastasia S. �� 39, 40 Tsagogiannis, Epaminondas �� 19 Tsakalof, Andreas �� 3, 19, 30 Tsakogiannis, Dimitrios �� 29 Tsakona, Dimitra �� 40 Tsakou, Anastasia �� 27 Tsalouchidou, Viktoria �� 31 Tsamesidis, Ioannis �� 31 Tsangaris, George Th. ��12, 30, 31 Tsaniklidis, Georgios �� 32 Tsaniras, Spyridon Champeris �� 24, 34 Tsapara, Anna �� 38 Tsaridou, Stavroula �� 28 Tsatsanis, Christos �� 8, 16, 33, 35, 36

Vafeiadi, Marina �� 38 Vakaloglou, Katerina M. �� 28 Vakonakis, Ioannis �� 18 Valerieva, Anna �� 37 Valmas, Alexandros �� 18, 40 Vamvakas, Sotiris S. �� 29 Vandera, Elpiniki �� 19 van Hooij, Onno �� 15 Varela, Aimilia �� 38 Vasileiou, Stella �� 26 Vassilacopoulou, Dido �� 27, 40 Vassiliou, Alice-Georgia �� 27 Vatsiou, Sofia �� 37, 38 Veletza, Stavroula �� 37, 38 Venihaki, Maria �� 37 Vergadi, Eleni �� 35 Verhaegh, Gerald �� 15 Verigos, John �� 15, 33 Verrou, Kleio-Maria �� 29 Villiou, Maria �� 15 Vizirianakis, Ioannis S. ��10, 14, 33 55

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Vlachakis, Dimitrios �� 39, 41 Vlachavas, Efstathios-Jason �� 30 Vlachiotis, Stelios �� 41 Vlachonikola, Elisavet �� 14 Vlahopoulos, Spyros �� 30 Vlahos, Konstantinos �� 35 Vlahou, Antonia �� 12, 31 Vlaikou, Angeliki-Maria �� 38 Vleeschouwer, Christophe De �� 28 Vorgias, Constantinos �� 35 Vorgias, Constantinos E. �� 12 Voulgaridou, Georgia-Persephoni �� 16, 41 Voutetakis, Konstantinos �� 30 Vynios, Demetrios H. �� 11 Vynios, Demitrios H. �� 26

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Zuccato, Cristina �� 35

Watanabe, Yasunori �� 14 Weigelt, Britta �� 15 Willis, Stefan �� 30 Windbichler, Νikolai �� 12

Xanthopoulos, Konstantinos �� 10, 34 Xefteris, Anastasios �� 36 Xylia, Konstantina �� 25

Yan, Zhe �� 19 Yfantis, Angelos �� 29 Yorkas, Loukas �� 37

Zacharopoulou, Nefeli �� 38 Zagoriti, Zoi �� 30 Zamanakou, Maria �� 37, 38 Zannis, Vassilis I. �� 14 Zarkadis, Ioannis K. �� 38 Zarogiannis, Sotirios G. �� 28, 29 Zervas, Christos G. �� 8, 10, 25, 28, 33 Zhang, Jinwei �� 16 Ziridou, Elpida �� 34 Zitouni, Sihem �� 27 Zografaki, Maria-Eleftheria �� 41, 42 Zographos, Spyros E. �� 18, 40 Zoidakis, Jeronymos �� 12, 31 Zompra, Aikaterini A. �� 40, 41 Zorba, Triantafyllia �� 31 Zoumpourlis, Vassilis �� 41 Zouridakis, Marios �� 18 www.eebmb-congress.gr

23-25 Νοεμβρίου 2018

69th Panhellenic Conference of the Hellenic Society for Biochemistry and Molecular Biology (HSBMB)

November 23-25, 2018 Imperial Hotel, Larissa www.eebmb-congress.gr

www.eebmb-congress.gr

69o Πανελλήνιο Συνέδριο

23-25 Νοεμβρίου 2018

Ελληνικής Εταιρείας Βιοχημείας & Μοριακής Βιολογίας

Hotel Imperial, Λάρισα www.eebmb-congress.gr

Εκθεσιακός χώρος | Exhibition Area

=1m2

1 Coffee Break

9 10

Entrance

Entrance 1 Lab Supplies 2 Antisel 3 Bioline 4 Sarstedt 5 Βιοδυναμική 6 Ζαφειρόπουλος 7 Bioemtech 8 9 Life Science Chemilab 10 Pegasus

Pegasus S.A. Scientific & Laboratory Equipment

11 Ridacom ΕΠΙΣΤΗΜΟΝΙΚΕΣ ΕΚ∆ΟΣΕΙΣ

ΠΑΡΙΣΙΑΝΟΥ

Α.Ε.

www.parisianou.gr medbooks@parisianou.gr

12 Εκδόσεις Παρισιάνου

Υποστήριξη από άλλες εταιρείς / other supporting companies: The Science Support, Aegis, Safe Blood Analytica www.eebmb-congress.gr

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