Pathophysiology of pain
Definition: Pain
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Pathophysiology of pain
Definition: Pain
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Pathophysiology of pain
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PNS
CNS Pathophysiology of pain
Nociception •
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Nociception
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Pathophysiology of pain
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Periphery Pathophysiology of pain
Periphery
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Pathophysiology of pain
Periphery
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Pathophysiology of pain
9 Pathophysiology of pain FIBERS Innervation Average ø Conduction velocity A�� Primary motor fibers destined to skeletal muscles 15 µm 100 m/sec Bβ Skin afferent fibers related to touch or pressure 8 µm 50 m/sec Aγ Muscle motor fibers 6 µm 20 m/sec Aδ Mechanoceptors, nociceptors, thermoreceptors <3 µm 15 m/sec B Sympathetic preganglionic fibers 3 µm 7 m/sec C Mechanoceptors, nociceptors, thermoreceptors, sympathetic postganglionic fibers 1 µm 1 m/sec
The spinal cord
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Pathophysiology of pain 11
Neurotransmitters important in pain pathways
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Comparisons of central pathways for pain transmission
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Transmission and modulation
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Pathophysiology of pain 16
Opioid receptors
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Pathophysiology of pain 18
The neuromatrix theory of pain
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