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Key Takeaways
KEY TAKEAWAYS
• There are thousands of solvents that share lipophilicity so they cross the bloodbrain barrier.
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• Toluene toxicity is often seen in teens who inhale fumes as part of recreational use.
• Hydrocarbons of all types can cause sudden death by sensitizing the heart to catecholamines, leading to an increase in ventricular dysrhythmias.
• Many solvents are carcinogens, leading to an increase in blood cancers and other cancers.
• Workers at risk for solvent toxicity include painters and those who work with fumes of all types.
• Vinyl chloride toxicity leads to hepatotoxicity and a risk of angiosarcoma of the liver.
• Some of the CNS effects of solvents is reversible after avoiding the exposure to the solvents.