Photonics startup Mantispectra takes

Photonics startup Mantispectra takes chemical analysis out of the lab

Who says chemical analysis needs to be performed in a laboratory, by well-trained personnel? Thanks to a photonic-chip-based spectral sensing system being commercialized by startup Mantispectra, classifying and quantifying material composition will never be easier.

Paul van Gerven

There’s only so much a farmer can tell about his crops just by looking at them. A tomato that has turned red, for example, is certainly getting closer to harvest. But when is it optimal to harvest? Dry mass, sugar content or the concentration of other tasty compounds may still be increasing, all of which will be wasted if the fruit is plucked too early.

By providing farmers with an extra set of eyes, startup Mantispectra aims to solve this problem. The spinoff from Eindhoven University of Technology (TUE) is developing a portable optical sensing system that, in mere seconds, yields a wealth of information about the chemical composition of a tomato. This information wouldn’t only be useful for determining optimal harvest timing but also for optimizing growth conditions and, after harvest, quality control in the distribution chain.

Of course, tomato farmers aren’t the only ones that can benefit from such a device. Not only does the technology extend to many other crops, but there are many applications outside of agriculture and food as well, such as in textile recycling, pharmaceutics and healthcare. Even consumer electronics is

within the realm of possibilities: imagine people using their smartphone, equipped with Mantispectra’s sensor, to determine if their milk has gone sour or how healthy their skin is.

“Taking spectrometers – which normally are bulky and expensive scientific instruments that require trained operators – out of the lab to perform real-time chemical analysis wherever needed opens up a great number of applications in many different markets. I’m sure we haven’t encountered, or even thought of, them all,” says CEO Maurangelo Petruzzella of Mantispectra. “Leveraging the expertise of the publicprivate photonics partnership Photondelta and the infrastructure that the Dutch integrated-photonics industry has already built up, I’m confident we can swiftly scale up our technology to take advantage of these opportunities.”

A little crazy

The young company’s name refers to the Mantis shrimp, a marine crustacean with one of the most complex eyes in the animal kingdom. Humans have three types of photoreceptor cells, which are sensitive to red, green and blue light. The Mantis shrimp’s eye contains up to sixteen photoreceptors, which can detect light ranging from the deep ultraviolet to the far red. The core technology of Mantispectra is a tiny chip that also has sixteen ‘photoreceptors’ on board, each detecting a different band of light. Unlike the sea animal, however, the chip only detects bands in the near infrared (near IR), which spans the 820-1680 nanometer range, from which a wealth of chemical information can be obtained.

“Our chip, roughly measuring 1 by 1 millimeter, consists of an array of sixteen indium gallium arsenide pixels bonded on silicon. The pixels differ only in the type of filter integrated within them, which is sensitive to a particular near-IR band. The operating principle of our sensing system is to shine broadband near-IR light on the sample and collect the reflected light with our chip. This results in a kind of ‘fingerprint,’ which is our raw information,” explains Petruzzella.

For the raw information to become useful, it needs to be plugged into a machine learning-based model, which correlates the measured reflection intensities (or lack thereof) to the chemical composition of the

sample. Drawing up such a model is quite a bit of work, but once done, you’ll never have to do the measurement the old- fashioned and time-consuming way again. For several interesting application cases, Mantispectra will provide a pre-made model that can be directly deployed. At the same time, the company will o er the possibility for the user to build new models to assist them in their creation and validation.

As proof of principle, Mantispectra is currently working with partners in the agro-food industry to build such a model. Going forward, the startup intends to provide interested parties – potential end-users, instrument vendors and system integrators – with its technology, so they can try it out for their applications. “To be honest, things are getting a little crazy right now. We’ve been receiving an incredible amount of inquiries from all over the world. With our resources, it’s challenging to comb through all of them and lter out the most promising ones,” says Petruzella.

Depending on the speci c use case, Mantispectra will market its own products or give out licenses for others to include the spectral technology in their products.

Mantis shrimp

Scaling up

e detector chip is the heart of Mantispectra’s product, but obviously it isn’t a standalone system. To become fully functional, it needs to be assembled into a module, which contains some basic optics, a light source and electronics to process the measurement and/or transfer the data via

Photondelta’s growth strategy

Photondelta was set up in January 2019 to boost the growth of the emerging Dutch integrated-photonics industry. Its mission: to drive growth in terms of turnover (over 1 billion euros), resources (over 4,000 FTE) and number of companies (more than 25) by 2026, leveraging funds made available by public parties. “ ese goals are challenging considering the double-trouble context, in addition to the relatively limited time frame and resources: a new emerging technology with – long-term – potential in likewise emerging applications and markets,” says Giuseppe Coppola, Chief Strategy and Business Development O cer at Photondelta.

To face this particular complexity and identify the most relevant growth opportunities, Photondelta, together with its partners, drove a structured approach. First, it performed a thorough analysis of relevant trends, drivers and product opportunities in a wide number of markets. en, the most attractive opportunities were evaluated versus the industry’s product and technological capabilities. is resulted, at the end of last year, in the identi cation of four key target markets: medical devices & life sciences, datacom & telecom, infrastructure & transportation and agriculture & food. Soon afterward, dedicated focal area teams, sta ed with business and technology experts from companies and knowledge institutes, have been set up and chartered to further sharpen relevant propositions and business/technology roadmaps, in open collaboration with global customers and end-users. ese insights have been guiding strategy and execution for further expansion of the portfolio o ering, acquisition of new customers and cluster partners, as well as Photondelta investments. e activities of Mantispectra are part of the agriculture & food market and fall under the focal area “NIR spectral sensing modules and components for analysis of fruit and vegetable nutrients, taste and structure insights.” USB to a computer. Having successfully developed prototypes, Mantispectra recently started production of a batch of fully functional modules for distribution to prospective customers and partners. In parallel, it has started working on industrialization challenges, such as assessing the reproducibility of the chips and modules and compliance with international standards.

For the moment, Mantispectra’s chips are fabricated at TUE’s cleanroom facilities. Once the technology gains traction and volumes pick up, however, the production process might be outsourced to local partners. “It’s great to be in this region because there already is a lot of activity in the area of integrated photonics. For us, having access to a local foundry and an assembly facility is invaluable,” says Italian-born Petruzella, who originally came to the Netherlands to carry out his PhD at TUE. e Dutch integrated-photonics ecosystem has united in the public-private partnership Photondelta (see inset “Photondelta’s growth strategy”), aiming to establish a world-leading industry. Photondelta fosters (international) collaboration, promotes knowledge sharing among members, charts roadmaps and supports companies, particularly startups, with business aspects. “Photondelta has been of great assistance, particularly with connecting this technology to early adopters. With all its knowledge and experience, I expect Photondelta will keep playing a key role in scaling up our business over the coming years.”