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1.What is Methyltestosterone? How does it Work?
Product Description Methyltestosterone is among the few synthetic old school anabolic steroids for bodybuilding. It is a chemical compound whose CAS no is 58-18-4. The product is a standard drug for bodybuilders as it exhibits androgenic and anabolic characteristics. Methyltestosterone is a pioneer oral test formulation, which derives from testosterone. What makes the compound unique is the inclusion of the alkylated C17-alpha molecule. Scientifically, the addition of a methyl group ensures that the drug can live through the mechanical breakdown and digestion processes in the body. In Methyltestosterone the methyl group affixes to the 17th position of the carbon atom. This aspect makes the compound to fall in the class of C-17 alpha-alkylated steroids. However, for Methyltestosterone bodybuilding, the anabolic properties are not as noticeable as it is with other C-17-aa compounds. The product’s androgenic and anabolic ratings are approximately 100 for each category. This 1:1 ratio corresponds to that of testosterone. Although this original testosterone leaves any bodybuilder with great lean muscles and excellent performance, its uses are universal. For instance, pharma grade 1
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Methyltestosterone has medical pluses in breast cancer treatment, menopausal therapy, and management of osteoporosis. History The existence of Methyltestosterone dates back to 1935. The steroid broke new ground for the use of oral androgens not only in clinical applications but also in the bodybuilding domain. The principal reason for the development of the drug was to replace the natural testosterone in males when the endogenous levels were lower than usual. Although Methyltestosterone for sale was available as an ingestible oral steroid, Ciba Pharmaceuticals came up with buccal tablets that would directly dissolve via the tongue. These drugs were all the rage between the 1950s and 1990s with a brand name, Metandren Linguets. Instead of swallowing Methyltestosterone pill, you could place the Metandren Linguets’ tablets below the tongue and allow them to dissolve. Upon absorption, the steroid circulates via the mucosal membranes without traversing the liver. Just like any other anabolic steroid, the use of this drug has remained controversial. In as much as it has a clean history, most countries have banned and filtered Methyltestosterone supplier out of the drug markets. Take, for instance, in the late 80s; the German Endocrine Society brought to a halt the commercialization of Methyltestosterone from German pharmacies. Subsequently, most European states followed suit and banned it due to the potential Methyltestosterone side effects such as hepatotoxicity. In m ost US countries, the drug is permissible for both clinical and medicinal purposes. However, it’s quite hard to find it as a stand-alone formulation since methyltestosterone manufacturer would always combine it with other ingredients. In the US, the drug is legal only under a valid prescription. Major athletic organizations including the International Olympic Committees have criminalized the use of methyltestosterone in sports. It is a Schedule III and IV substance in the United States and Canada, respectively. How Methyltestosterone Works Being an alpha alkylated steroid, Methyltestosterone binds to the androgen receptors (AR). It acts as a substrate for the 5α-reductase enzyme, hence, transforming into 17α-methyl-dihydrotestosterone (mestanolone). After binding to the AR cells, the steroid initiates the transcription of androgen-responsive genes, which are responsible for massive growth and secondary sexual characteristics. 2
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Unlike other derivatives of testosterone, methyl test has a lower rating of anabolic activity. Therefore, the anabolic to androgenic ratio is slightly smaller, making the steroid to have relatively higher androgenic properties. The critical downside of methyltestosterone bodybuilding steroid is that it aromatizes during the mechanism of action in the body. The aromatization into a more potent 17Îą-methyl estradiol triggers estrogenicity and subsequent estrogenic side effects like water retention and gynecomastia.
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