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CLOMIPHENE CITRATE(CLOMID) (50-41-9) Clomiphene Citratrate is used to treat infertility in women. It works by stimulating an increase in the amount of hormones that support the growth and release of a mature egg (ovulation). This medication is not recommended for women whose ovaries no longer make eggs properly (primary pituitary or ovarian failure).
Status:
In Mass Production
Unit:
25kg/Drum
Capacity: 1230kg/month
Clomiphene Citrate(Clomid) (50-41-9) video Clomiphene Citrate(Clomid) (50-41-9) Description Clomiphene Citratrate is used to treat infertility in women. It works by stimulating an increase in the amount of hormones that support the growth and release of a mature egg (ovulation). This medication is not recommended for women whose ovaries no longer make eggs properly (primary pituitary or ovarian failure). Clomiphene Citrate is an orally administered, non steroidal, ovulatory stimulant that acts as a selective estrogen receptor modulator (SERM). Clomifene can lead to multiple ovulation, and hence increase the risk of conceiving twins. In comparison to purified FSH, the rate of ovarian hyperstimulation syndrome is low. There may be an increased risk of ovarian cancer and weight gain. Clomifene is capable of interacting with estrogen-receptor-containing tissues, including the hypothalamus, pituitary, ovary, endometrium, vagina, and cervix. It may compete with estrogen for 1
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estrogen-receptor-binding sites and may delay replenishment of intracellular estrogen receptors. Clomifene initiates a series of endocrine events culminating in a preovulatory gonadotropin surge and subsequent follicular rupture. The first endocrine event, in response to a course of clomifene therapy, is an increase in the release of pituitary gonadotropins. This initiates steroidogenesis and folliculogenesis resulting in growth of the ovarian follicle and an increase in the circulating level of estradiol. Following ovulation, plasma progesterone and estradiol rise and fall as they would in a normal ovulatory cycle.
Clomiphene Citrate(Clomid) (50-41-9) Specifications Product Name
Clomiphene Citrate(Clomid) (50-41-9)
Chemical Name
Clomifene citrate; Clomid
Brand Name
Clomid
Drug Class
selective estrogen receptor modulator (SERM)
CAS Number
50-41-9
InChIKey
PYTMYKVIJXPNBD-UHFFFAOYSA-N
Molecular Formula
C32H36ClNO8
Molecular Weight
598.089 g/mol
Monoisotopic Mass
597.213 g/mol
Melting Point
116.5-118°C
Freezing Point
No data available
Biological Half-Life
5-7days
Color
White powder
Solubility
Slightly soluble in water, methanol, chloroform (slightly), and DMSO (10 mM). Insoluble in ether.
Storage Temperature
2-8°C
Application
used to treat infertility in women
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