Everything You Need To Know About Hesperidin Methylchalcone Powder (24292-52-2)

www.scienceherb.com

Hesperidin Methylchalcone Powder (24292-52-2)

Hesperidin methyl chalcone (HMC) is a methylated derivative of the flavonoid compound hesperidin and is also a flavanone glycoside (flavonoid) found abundantly in citrus fruits. It is found in several fruits, particularly citrus fruits, the majority of which are grown in Spain. The compound takes the form of a pale yellow, slightly bitter, water-soluble powder.

Hesperidin Methylchalcone powder Specifications

1

scie10@scienceherb.com

www.scienceherb.com Name:

Hesperidin powder

CAS:

24292-52-2

Function:

Hesperidin Methyl Chalcone acts as an antioxidant, which contributes to the integrity of the blood vessels and reduced cholesterol and blood pressure in rats. In a mouse study large doses of the glucoside hesperidin decreased bone density loss.

Another animal study showed protective effects against sepsis.

Hesperidin has anti-inflammatory effects..

Hesperidin is also a sedative, possibly acting through adenosine receptors.Some in vitro results applied only to the aglucone form. Hesperidin also showed the ability to penetrate the blood brain barrier in an in vitro model.

Application:

Methylchalcone

Applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of alcoholicbeverage, dessert foods and savory foods; Applied in cosmetics, it can added into toothpaste and mouth wash ; Applied in pharmaceutical field,

2

scie10@scienceherb.com

www.scienceherb.com it is mainly used to reducing the bitterness of in form.

Solubility:

water-soluble

Storage Temp:

Keep Dry and Keep away from Sunlight

Color:

Light Yellow Powder

What isHesperidin Methylchalcone powder?

Hesperidin methyl chalcone (HMC) is a methylated derivative of the flavonoid compound hesperidin and is also a flavanone glycoside (flavonoid) found abundantly in citrus fruits. It is found in several fruits, particularly citrus fruits, the majority of which are grown in Spain. The compound takes the form of a pale yellow, slightly bitter, water-soluble powder.

3

scie10@scienceherb.com

www.scienceherb.com

Its aglycone form is called hesperetin.Hesperidin is believed to play a role in plant defense. It acts as an antioxidant according to in vitro studies. In human nutrition it contributes to the integrity of the blood vessels.Various preliminary studies reveal novel pharmaceutical properties. Hesperidin reduced cholesterol and blood pressure in rats. In a mouse study large doses of the glucoside hesperidin decreased bone density loss. Another animal study showed protective effects against sepsis. Hesperidin has antiinflammatory effects.. Hesperidin is also a sedative, possibly acting through adenosine receptors.

Hesperidin Methylchalcone powderuses

With a long history of popular use in Asia, hesperidin methyl chalcone has now made a ‘grand entrance’ in Europe. Drawing on the many studies conducted on the compound, hesperidin has been formulated into venotropic drugs and nutritional supplements aimed at improving the circulation and combatting certain venous disorders. It is widely-used in Japan, as well as in Europe both as a nutritional supplement and an ingredient in cosmetics. It is also available in pharmacies, mainly in combination with other plants such as butcher’s broom, for treating circulation problems.

Hesperidin Methylchalcone powderbenefits

Like all flavonoids, HMC is a powerful antioxidant, and is thus excellent for optimising eye health and protecting the cardiovascular system from oxidative attack.

Its main activity, widely-supported by clinical studies, lies in maintaining blood vessel integrity and strengthening the capillary network:

Hesperidin has been formulated into venotropic drugs and nutritional supplements aimed at improving the circulation and combatting certain venous disorders.

4

scie10@scienceherb.com

www.scienceherb.com In a short space of time, hesperidin has come to be seen as an effective treatment for symptoms of venous insufficiency, such as cramps or ‘heavy legs’.

It is used in certain drugs as an effective solution to haemorrhoids, particularly in reducing incidence of attacks.

In addition to its pharmaceutical use, hesperidin has also proved of interest to the cosmetics industry. This is primarily because of its antioxidant potency which may combat free radical damage, prevent the effects of oxidative stress, and thus delay cellular ageing.

As it helps improve the circulation, hesperidin has also been suggested as a skincare ingredient, aimed at easing the sensation of heavy, tired legs and making them feel lighter and more toned.

Hesperidin Methylchalcone powderdosage

These latter developments suggest that HMC may also play a key role in approaches to age-related disorders – in preventing or even treating them. But it is really the compound’s overall effects, particularly those related to general circulatory problems, which make such a strong case for supplementing with this very safe product – ideally at a dose of 500-1000mg/day for 2-3 months.

Hesperidin Methylchalcone powderfor sale (Where to Buy Hesperidin Methylchalcone powder)

Our company enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time.

5

scie10@scienceherb.com

www.scienceherb.com We also focus on value-added services. We are available for service questions and information to support your business.

We are an professional Green tea extract powder supplier for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

References

6



Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice

by Inhibiting NF-κB Activation.Ruiz-Miyazawa KW et al. J Agric Food Chem.

(2018)



Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease.Allaert FA et al.

Int Angiol. (2016)



The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease.Jawien A et al. Int Angiol. (2017)



Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice

by Inhibiting NF-κB Activation.Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Borghi SM, Staurengo-Ferrari L, Fattori V, Amaral FA, Teixeira MM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr.J Agric Food Chem. 2018 Jun 27;66(25):6269-6280. doi: 10.1021/acs.jafc.8b00959.

Epub 2018 Jun 13.



The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease.Jawien A, Bouskela E, Allaert FA,Nicolaïdes AN.Int Angiol.

2017 Feb;36(1):31-41. doi: 10.23736/S0392-9590.16.03788-3. Review.

scie10@scienceherb.com