Everything You Need To Know About Methyl Hesperidin Powder (11013-97-1)

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Methyl Hesperidin Powder (11013-97-1)

Methyl hesperidin is a flavanone glycoside that is hesperidin in which the hydroxy group at position 3′ has been replaced by a methoxy group. Methyl hesperidin has potentiating effect on coronary vasodilation induced by adenosine or related compounds, It caused inhibition of nitrendipine transport in the ileum and jejunum, but not in the duodenum. Methyl hesperidin exerts no obvious toxic effects in mice of either sex when administered at a level as high as 5.0% in the diet.

Methyl Hesperidin powder Specifications 1

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Methyl Hesperidin powder

CAS:

11013-97-1

Function:

Supports and protects the integrity of the vascular system with particular acitivity in the capillaries and veins. It has been shown to help strengthen capillaries by increasing capillary resistance and decreasing capillary permeability.

Application:

1. As a natural antioxidant, it is mainly used in cosmetic industry.

2. As a natural antioxidant, it is widely used in health product and food industry.

3. As raw materials of drugs for lowering cholesterol, anti-virus and anti-inflammatory, it is mainly used in pharmaceutical field.

Solubility:

water-soluble

Storage Temp:

Keep in cool and dry place

Color:

Light Yellow Powder

What is Methyl Hesperidin powder?

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www.scienceherb.com Methyl hesperidin is a flavanone glycoside that is hesperidin in which the hydroxy group at position 3′ has been replaced by a methoxy group. Methyl hesperidin has potentiating effect on coronary vasodilation induced by adenosine or related compounds, It caused inhibition of nitrendipine transport in the ileum and jejunum, but not in the duodenum. Methyl hesperidin exerts no obvious toxic effects in mice of either sex when administered at a level as high as 5.0% in the diet.

Methyl Hesperidin powderuses

Methyl hesperidin is water solubility compound of various flavanone hesperidin. It has the same effect with vitamin P, which has enhancement function to vitamin C.

What’s more, characters in strong anti-virus and anti-bacteria. It is preventing influenza virus’ breeding with large dosage, inhibiting tyrosinase which causing skin to black. For the treatment of black spot, freckle such skin disease. It has an effect on remaining normal permeability, boosting resistance, enhancing elastic and toughness of vessels, preventing and curing blooding of capillary or gums.

With the same pharmacologic action as hesperidin, methyl hesperidin can strengthen resistance of capillary, so that keeping normal permeation and preventing vascular disorders caused by arteriosclerosis. It has magnificent effect together with vitamin C which is available for nose bleeding, retinal hemorrhage, gums or alveoli bleeding, gastrointestinal bleeding, hemorrhoid bleeding etc. and for the treatment or prevention of pre-operation and post-operation bleeding.

Methyl Hesperidin powderbenefits

Methyl Hesperidine is extracted from citrus (Bitter Orange) immature young fruit, which has the following major benefits:

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Antioxidant, anti-inflammatory, hypolipidemic, anticarcinogenic and cholesterol lowering actions;

vasoprotective

and

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Inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase;

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Improve the health of capillaries by reducing the capillary permeability;

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Reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells;

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The possible anti-cancer activity of hesperidin could be explained by the inhibition of polyamine synthesis.

Methyl Hesperidin powder dosage

The appropriate dose of Methyl Hesperidin powder depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for sea buckthorn.

Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Methyl Hesperidin powder for sale(Where to Buy Methyl Hesperidin powder)

Our company enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time.

We also focus on value-added services. We are available for service questions and information to support your business.

We are an professional Green tea extract powder supplier for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

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References

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Development of nobiletin-methyl hesperidin amorphous solid dispersion: Novel application of methyl hesperidin as an excipient for hot-melt extrusion.Iwashita M, Hashizume K, Umehara M, Ishigami T, Onishi S, Yamamoto M, Higashi K, Moribe K.Int J Pharm. 2019 Mar 10;558:215-224. doi: 10.1016/j.ijpharm.2018.12.092. Epub 2019 Jan 14.

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Hydrolyzed Methylhesperidin Induces Antioxidant Enzyme Expression via the Nrf2-ARE Pathway in Normal Human Epidermal Keratinocytes.Kuwano T,Watanabe M, Kagawa D, Murase T.J Agric Food Chem. 2015 Sep 16;63(36):7937-44. doi: 10.1021/acs.jafc.5b01992. Epub 2015 Sep 8.

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Molecular spectroscopic on interaction between Methyl hesperidin and Buman serum albumin.Li J, Wang S.Spectrochim Acta A Mol Biomol Spectrosc. 2013 Feb;102:200-4. doi: 10.1016/j.saa.2012.10.012. Epub 2012 Oct 23.

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Subchronic toxicity study of methyl hesperidin in mice.Kawabe M, Tamano S, Shibata MA, Hirose M, Fukushima S, Ito N.Toxicol Lett. 1993 Jul;69(1):37-44.

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Carcinogenicity study of methyl hesperidin in B6C3F1 mice.Kurata Y, Fukushima S, Hagiwara A, Ito H, Ogawa K, Ito N.Food Chem Toxicol. 1990 Sep;28(9):613-8.

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