Cabrini institute annual report 2013 14 lr (1) by Cabrini Health

Cabrini Institute Annual Report 2013-14

About the Cabrini Institute 2

Established in 1996, the Cabrini Institute supports a wide

in clinical education. The research program includes

range of research and education activities across Cabrini,

arthritis, back pain, cancer, care of the elderly, health

as well as health promotion activities on behalf of the

literacy, medicine, nursing, patient safety and surgery.

organisation. Senior medical staff and researchers oversee

The Cabrini Institute has a significant role in the education

a diverse research program, as well as developments

of our young health professionals.

ABOUT THE COVER

Matthew Johnson joined Cabrini as Manager of the Stewardson Charitable Trusts Simulation Centre. Since opening, more than 300 simulation training activities have taken place involving more than 700 students and staff.

Education. Research. Health promotion.

TABLE OF CONTENTS

6 Year in review 8 Monash Department of Clinical Epidemiology at Cabrini Hospital 12 Cabrini Monash University Department of Medical Oncology The Szalmuk Family Department of Medical Oncology 16 Cabrini Monash University Department of Medicine 20 Cabrini Centre for Nursing Education and Research 22 Cabrini Monash University Department of Surgery The FrĂśhlich West Chair of Surgery 24 Clinical education at Cabrini 28 Cabrini Monash Psycho-Oncology 30 Allied Health Research Unit 32 Health promotion 38 Department staff 44 Supporting ethical research 54 Publications 64 Governance â&#x20AC;&#x201C; Cabrini Institute Council 69 Supporters

Facts and highlights

1996 03 47 07

Cabrini Institute established

university partnerships

medical oncology clinical trials

editorials, columns, letters to the editor

03 05 79 91

main areas of focus: education, health promotion, research

academic departments

presentations delivered

journal publications

116

projects reviewed by Cabrini Human Research Ethics Committee

GOVERNED

by Cabrini Institute Council

CHAIRED

by Professor Lawrence St Leger

12-MEMBER

Cabrini Institute Council

Year in review

he Cabrini Institute supports research, clinical education and health promotion, in order to provide an evidence base to improve patient care and the health of our patients and the community.

Reverend Monsignor Anthony Ireland, Episcopal Vicar for

researchers. In its first full year, it is anticipated that 500

Health and Aged Care.

students will participate in clinical education there and

The past year has seen the development of a wonderful, new, permanent home for the Cabrini Institute, as well as major changes in education, nursing research and leadership of the Cabrini Institute Council.

areas to support modern clinical education – was possible

The $7.5m, four-storey building – which houses a hightech simulation centre, an e-library and multiple teaching due to funding made available by Health Workforce

more than 600 clinicians will be involved in education, training and research. Developments in nursing education and research

Australia (HWA), an initiative of the Council of Australian

In early 2014, the Cabrini Institute Council and the

Governments. The functions of HWA were taken over by

Cabrini Board of Directors approved the establishment

The Cabrini Institute Annual Report 2013-14 highlights the scope of education, research and health promotion across our health service. In this report, we list all projects approved by the Cabrini Human Research Ethics Committee and all publications by our researchers.

the Commonwealth Department of Health and Ageing

of the Cabrini Nursing Education and Research Centre.

from July 2014.

This followed a review that was informed by analysis of

The Patricia Peck Education and Research Precinct

support of the library and the Trustees of the Stewardson

The new home for the Cabrini Institute was opened on 12 November 2013 by the then-Mayor of Stonnington Councillor Matthew Koce and was blessed by the

The building is named in honour of Mrs Patricia Peck, a major donor to the Cabrini Institute. Other major donor supporters for the precinct are Lee and Brian Johnston in Trusts who supported the simulation centre.

our nursing workforce recruitment and needs in the area of skill development, as well as by meetings with our university partners. Associate Professor Lee Boyd is leading the new Cabrini Nursing Education and Research Centre. At this stage, the Centre will not have a single university partner for nursing research,

The Patricia Peck Education and Research Precinct

although we continue to conduct research projects

is Cabrini’s permanent base for students and clinical

with university partners.

From left: Professor Lawrence St Leger, Chair, Cabrini Institute Council. Dr Peter Lowthian, Executive Director, Cabrini Institute and Clinical Governance

In its first full year, it is anticipated that 500 students will participate in clinical education there and more than 600 clinicians will be involved in education, training and research.

Expanding clinical education Cabrini remains committed to the education of our future healthcare workforce. Our relationships with Health Workforce Australia (HWA) and our university partners continue to support the expansion of clinical places in our health service. The Commonwealth Specialist Training Program continues to support specialist training for postgraduate doctors. Our nursing education program continues to grow. As well as undergraduate students from Deakin and Australian Catholic universities, in 2014 we had student nursing placements from Monash University for the first time. The graduate year nurses’ program continues, and support is provided for postgraduate training courses. The Cabrini Institute’s department of education is currently undertaking a review of nursing education, the outcome of which will inform future developments.

Cabrini’s allied health services continue to grow. In 2014, we developed new partnerships in allied health with Holmesglen Institute and La Trobe University. During 2014, the number of Monash University undergraduate medical students in clinical placements increased slightly, with students from each of the three clinical years. Cabrini Institute leadership and governance The Cabrini Institute Council oversees the governance and work of the Cabrini Institute, as well as research across Cabrini. Professors Robert Thomas and Gerald Farrell retired from the Council during the year. We acknowledge their contributions to the Institute. Council Chair Professor Lawrence St Leger retired in May after seven years in the role. The Cabrini Institute and Cabrini have appreciated his leadership and advice. Professor Peter Fuller took over as Chair in May 2014.

We would be unable to carry out our work without our committed research and administrative staff, the doctors and the nurses who support the clinical education programs and the work of the Cabrini Human Research Ethics Committee, as well as the support and encouragement of the Missionary Sisters of the Sacred Heart of Jesus and Cabrini’s Board of Directors. Once again we express our thanks and appreciation to all of them, as well as to our wonderful donors and sponsors for their continued support.

Dr Peter Lowthian Executive Director, Cabrini Institute Professor Lawrence St Leger Chair, Cabrini Institute Council

Monash Department of Clinical Epidemiology at Cabrini Hospital

he Monash Department of Clinical Epidemiology at Cabrini Hospital focuses on performing high quality, clinical research with an emphasis on answering clinically important questions that can be translated into better quality patient care and outcomes. During the past 12 months, two visiting professors spent time in our department as part of their sabbaticals.

Professor Francis Guillemin (France) Professor Francis Guillemin, a rheumatologist and epidemiologist, is an expert in the cross-cultural adaptation of questionnaires and he has developed the OAKHQOL questionnaire. This is a French tool that assesses disease-specific quality of life in people who have osteoarthritis of the knee and hip. During Professor Guilleminâ&#x20AC;&#x2122;s sabbatical, we finalised collaboration in the APPROVALS project. This will determine which of four Australian versions of the instrument is preferred in an Australian cohort of people who have knee and

Above: Professor Rachelle Buchbinder

hip osteoarthritis. We adapted the evaluative linguistic framework (ELF), a tool for assessing the quality of written patient information, into the ELF-Q for assessing the quality of patient questionnaires. Professors Guillemin and Buchbinder presented this work at a workshop at the Outcomes Measures in Clinical Trials in Rheumatology (OMERACT) meeting in Budapest held in May 2014.

department, is leading this work funded by an Arthritis Australia grant. Dr Slade, a physiotherapist, is also completing a systematic review of qualitative studies investigating why general practitioners do not follow guidelines for the management of low back pain.

Professor Clermont Dionne (Canada) Professor Clermont Dionne is a musculoskeletal epidemiologist who led an international consensus project to develop a standard definition of low (lower) back pain for use in epidemiologic studies, which has been adopted internationally. During Professor Dionneâ&#x20AC;&#x2122;s sabbatical, he provided invaluable input into a similar international consensus project. In this project, we are seeking to develop a standard reporting checklist for use in trials of exercise. This will allow replication of the intervention in further research and/or clinical practice. Dr Susan Slade, a new postdoctoral researcher in our

During 2013-14, a series of Cochrane systematic reviews were completed. They have synthesised the evidence for effectiveness and safety of interventions commonly used to treat acute and chronic gout including allopurinol, colchicine, NSAIDs and diet. These reviews informed multinational and national recommendations for the diagnosis and management of gout.

Systematic reviews, trials and results

We are continuing to recruit participants to an NHMRCfunded, randomised, controlled trial designed to compare the effect of autologous platelet-rich plasma injection to glucocorticoid injection and placebo for lateral epicondylitis (tennis elbow). This trial began in 2013. The

results will inform clinical practice and policy, particularly as public funding for all autologous blood injections will cease from the end of 2014. An additional recruitment site has been set up in Sydney and Dr Allison Bourne is coordinating this project.

and received wide national and international attention, as it questions the utility of these programs. Based upon 29 trials, we concluded that self-management education programs, as studied in these trials, are unlikely to provide any important clinical benefits.

The two-year clinical outcomes from an NHMRCfunded trial of vertebroplasty for osteoporotic vertebral fractures were published in the Journal of Bone and Mineral Research. The results were in keeping with the six-month trial results, which found that there were no between-group differences in outcome compared with a sham procedure. Feline Kroon, a medical student from Maastricht University in The Netherlands, wrote up these results during a visiting internship in our department and Dr Margaret Staples performed the analysis. During their internship she and Lennart van der Berg (another visiting medical student from Maastricht University) completed their Cochrane review of self-management education programs for osteoarthritis. This review was published

Shehzaad Peerbux (a BBioMed Sci student from Monash University) is investigating the health literacy profile of recent inpatients at Cabrini Malvern under the supervision of Dr Allison Bourne. Approximately 1000 responses have been received. When completed, the results will provide Cabrini with important information about patients’ needs. It may identify interventions that could be implemented within Cabrini, which could improve health literacy. Major projects • Is autologous platelet-rich plasma injection effective for tennis elbow? • Understanding the health literacy of patients attending Cabrini Health

From left: Professor Rachelle Buchbinder is a practising rheumatologist, active in research and head of the head of the Monash Department of Clinical Epidemiology at Cabrini Hospital. A model of a skeleton is helpful in discussions with students and patients.

• OPtimising Health LIterAcy (OPHELIA) Project • Understanding the burden of back pain – the BP-Quest • A standardised method for reporting exercise programs in clinical trials • The long-term outcomes of people with inflammatory arthritis in Australia (ARAD) Research outcomes An NHMRC-funded, randomised, controlled trial involving 102 participants was completed, in which researchers investigated the effects of physical therapy in people who have osteoarthritis of the hip. The results were reported in the Journal of the American Medical Association in June 2014. The trial, led by Professor Kim Bennell at the University of Melbourne and supported by Professor Buchbinder, found that physical therapy did not result in greater improvement in pain or function compared with sham treatment.

Monash Department of Clinical Epidemiology at Cabrini Hospital

Grants NHMRC Project Grant (2010-14) Project title: A randomised, controlled trial to evaluate the efficacy of bisphosphonate therapy in patients with osteonecrosis of the hip Applicants: Sambrook P, Little D, March L, Buchbinder R. NHMRC Project Grant 1049823 (2013-15) Project title: Comparative effectiveness of ultrasoundguided injection with either autologous platelet rich plasma or glucocorticoid for ultrasound-proven lateral epicondylitis: a three-arm, randomised placebocontrolled trial Applicants: Buchbinder R, Harris A, Staples M. ARC Linkage Project Grant 120200111 (2013-15) Project title: Enhancing health literacy to optimise health equality across Victorian communities Applicants: Osborne R, Buchbinder R, Beauchamp A.

Netherlands Organisation for Health Research and Development (2013-15) Project title: A patient and professional based multimedia campaign as innovative implementation strategy to improve low back pain guideline adherence: A costeffectiveness evaluation Applicants: Anema JA, Dr. C.R.L. Boot CRL, Braspenning J, Buchbinder R, Elders P, Schaafsma FG, van Tulder MW, van der Wouden JC. NHMRC Cochrane Funding (2013-15) Project title: Cochrane Musculoskeletal Review Group (CMSG), Australian satellite Applicants: Buchbinder R, Johnston R. Cabrini Institute (2013-14) Project title: Understanding the health literacy of patients attending Cabrini Health Applicant: Buchbinder R.

NHMRC Project Grant 1062638 (2014-18) Project title: A multicentre, double blind, randomised, placebo-controlled trial of oral anticoagulation in systemic sclerosis-related pulmonary arterial hypertension Applicants: Nikpour M, Buchbinder R, Prior D, Nandurkar H, Williams T, Gabbay E, Proudman S, Nash P. Zochling J, Stevens W. Arthritis Australia Grant In Aid (2014) Project title: Standardised method for reporting exercise programs Applicants: Slade S, Buchbinder R, Underwood M.

Mary Lane ADVANCING CABRINI’S CANCER RESEARCH

ecruiting for research trials, coordinating information for ethics submissions, liaising with

laboratories . . . it’s all in a day’s work for Cabrini’s Mary Lane. As one of six Study Coordinators at the Cabrini Institute – and the only one with specific training in oncology – Mary plays a critical role in advancing Cabrini’s cancer research. “My role is very varied. There’s a lot of patient contact,” says Mary. “At the moment, we have 22 clinical trials. I’ve just put 32 patients on a study and I’m currently recruiting for another three. “I help to answer questions patients might have before they make a decision to participate. Once the consent form is signed, I’ll organise scans and other procedures, and coordinate all their visits. Often I can administer or check their drugs. I’ll even take their bloods – I’m a qualified haematology nurse and I like to keep my hand in. “You develop relationships with patients as they are going through their personal experience of cancer and their treatment journey,” says Mary. “Having good communication is important. Being there to support the patient is a big part of what I do.” Six years into the role, Mary still relishes the work. “Research has always been an interest of mine. I still have patient contact, but also get the opportunity to see how new drugs perform on specific tumour streams. I’ve seen treatment become more targeted, which reduces patients’ exposure to drugs. Everyone’s a winner when treatment can be more individualised and targeted.”

Cabrini Monash University Department of Medical Oncology The Szalmuk Family Department of Medical Oncology

his department established in 2003 aims to provide compassionate, state-of-the-art care for cancer patients and continued advancements in the prevention, diagnosis, treatment and cure of cancer via a combination of research, education and clinical practice. Research agenda After several years of expansion, the departmentâ&#x20AC;&#x2122;s research agenda has stabilised with consolidation of a number of programs initiated over the previous 12 months including Brightways: A Cabrini Breast Cancer Service and the Cabrini Cancer Research Group. The Cabrini Cancer Research Group consists of a group of individuals within Cabrini who represent various disciplines. It has led to the initiation of one study in breast cancer rehabilitation and a number of projects currently in development. Studies with new cancer agents continue to dominate our research program. In particular, the department has developed specific expertise in clinical trials involving

Above: Associate Professor Gary Richardson

targeted therapies. These are drugs or other substances that block the growth and spread of cancer by interfering with specific molecules (molecular targets) that are involved in the growth, progression and spread of cancer. Targeted therapies differ from standard chemotherapy in that they act on specific molecular targets that are associated with cancer, whereas most standard chemotherapies act on all rapidly dividing normal and cancerous cells. Targeted therapies are currently the focus of much anti-cancer drug development. These therapies are a cornerstone of precision medicine, a form of medicine that uses information about a personâ&#x20AC;&#x2122;s genes and proteins to prevent, diagnose and treat disease. Current studies Current drug trials There is a wide spectrum of specific disease trials currently being undertaken. These are mainly phase 2 and 3 drug trial studies.

Current trials (patient recruitment phase)

Non-recruiting trials (patients still followed)

Breast cancer

Colorectal cancer

Kidney cancer

Lung cancer

Lymphoma

Multiple myeloma

Melanoma

Myelodysplastic syndrome

Ovarian cancer

Pancreatic cancer

Prostate cancer

Sarcoma

General

Total

Disease

Cancer of unknown primary study As previously reported in the Cabrini Institute Annual Report 2012-13, a diagnosis of carcinoma of unknown primary (CUP) is made when a patient presents with metastatic disease for which no primary cancer can be identified despite extensive clinical assessment, medical imaging and pathological evaluation. Currently, there is virtually no evidence to guide diagnostic treatment or supportive care practices for patients who have CUP.

A detailed understanding of the molecular biology, as well as the clinical, quality of life and psychosocial characteristics of this heterogeneous group of patients, is essential to underpin future clinical trials. This is a national collaborative cohort study of CUP by a team of leading laboratory, clinical, and behavioural researchers, as well as consumer advocates. The focus of this protocol is on ascertaining a cohort of CUP patients and collecting their relevant clinical, biological and psychosocial data, in order to: 1. Describe the clinical, quality of life, and psychosocial characteristics of the CUP cohort 2. Establish a biobank/databank resource of information on this cohort of CUP patients with biospecimens, and associated clinical, quality of life, and psychosocial data. A development in this area is SUPER: an independent, investigator-initiated study conducted through the

national collaboration of leading investigators dedicated to advancing the understanding and treatment of CUP patients. The study, which includes the establishment of a biobank/databank resource, will be coordinated by the project staff based at Peter MacCallum Cancer Centre in Melbourne, Victoria. Patients will be recruited from CUP oncology clinic at Peter MacCallum Cancer Centre, oncology clinics at Royal Prince Alfred Hospital, Flinders Medical Centre, Westmead Hospital and Cabrini. Brightways Breast Cancer Database International and national evidence has identified multidisciplinary care as key to the provision of bestpractice treatment and care for cancer patients. This involves a team approach to treatment planning as well as to care provision throughout the complete patient pathway. In response to research and identified patient needs, Cabrini developed Brightways: A Cabrini Breast Cancer Service.

From left: Cabrini Breast Cancer Coordinator Vicki Durston has spearheaded a clinical trial to confirm the effectiveness of scalp cooling technology in reducing hair loss among early breast cancer patients undergoing chemotherapy. Associate Professor Gary Richardson attended the inaugural 2012 Brightways luncheon. Cabrini is one of five healthcare services recruiting patients for a study designed to better understand and treat cancer among patients whose primary cancer is unidentified.

Cabrini Monash University Department of Medical Oncology The Szalmuk Family Department of Medical Oncology

As previously reported in the Cabrini Institute Annual Report 2012-13, the aim of the Brightways breast cancer database is to enable information to be collected on all patients who have breast cancer. The database allows analysis of outcome measures for all areas of treatment. Also, we are able to develop research projects around the database. All patients diagnosed with breast cancer at Cabrini are now captured at initial diagnosis. The following data is captured: patient characteristics, tumour staging and histology characteristics, type of treatment administered, toxicity of treatment, disease recurrence and survival. Cancer 2015 project Cabrini continues to participate in a major project: Cancer 2015. It is sponsored by the Victorian Cancer Agency. Phase 2 of the project involves recruitment of a further 4000 cancer patients at diagnosis over the course of the next two years, using the infrastructure and methods

developed in phase 1 of the study. We propose to follow these patients through the course of their illness, collecting a comprehensive set of biological samples and clinical and health economic data. The patients will be collected from 14 sites, spanning a broad range of metropolitan, rural, public and private institutions. Cancer genetic studies The Family Cancer Clinic at Cabrini continues to provide counselling and information for families who have a history of cancer. It addresses inheriting cancer, individual risk, screening and strategies to reduce risk of cancer. The clinic provides genetic testing where appropriate. Cabrini is continuing to recruit patients to two studies being conducted by Dr Yoland Antill:

2) Integration of genetic testing for risk associated genomic variants and rare predisposition genes into the management of high risk hereditary breast cancer families (variants in practice study)

1) Too much too soon? The impact of treatment-focused genetic testing in patients newly diagnosed with breast cancer

2. VCA Grant – Cancer 2015

Research grants and funding 1. Cancer Australia Grant – SUPER Study

3. Cooperative Groups • Australasian Gastrointestinal Trials Group

Associate Professor Henry Debinksi, a gastroenterologist, works at the Melbourne Gastrointestinal Investigation Unit at Cabrini. He was involved with the establishment of the Cabrini Family Cancer Clinic.

• Australasian Leukaemia and Lymphoma Trials Group • National Cancer Research Network (UK) 4. Pharmaceutical Industry • Allos Therapeutics • Amgen Inc. • Celgene Corporation • F. Hoffmann-La Roche Ltd. • Janssen Asia-Pacific • Medivation Inc. • Novartis Oncology • Teva Pharmaceutical Industries Ltd. 5. Ulm University (Germany) Education The Cabrini Institute appointed the first advanced trainee in medical oncology in 2011. There has previously been an advanced trainee in haematology for the past five years. Both positions are accredited by the Royal

Australasian College of Physicians. The oncology position has been created in partnership with the Alfred Hospital, with two registrars each spending six months at Alfred and Cabrini. It is part of the Victorian Medical Oncology Training Program. Partner organisations American Association for Cancer Research American Society of Clinical Oncology Australasian Gastro-Intestinal Trials Group Australasian Leukaemia and Lymphoma Study Group Australia and New Zealand Breast Cancer Trials Group Australia New Zealand Gynaecological Oncology Group Clinical Oncology Society of Australia Clinical Trials Australia Gynaecology Oncology Group – USA Haematology Society of Australia International Association for the Study of Lung Cancer International Society of Gynaecologic Oncology

From left: Dr Rachel Delahunty is an advanced trainee in medical oncology – she is pictured in Cabrini Brighton’s day oncology unit. Oncologist Dr Michelle White spoke at the inaugural 2012 Brightways luncheon.

Medical Oncology Group of Australia Monash Comprehensive Cancer Consortium Monash Partners Academic Health Sciences Centre Peter MacCallum Cancer Institute Private Cancer Physicians of Australia Southern Melbourne Integrated Cancer Service Thoracic Society of Australia Victorian Cooperative Oncology Group Relationships Cancer Australia Cancer Council: Victorian Cooperative Oncology Group Cancer Institute of NSW: Evi-Q Clinical Trials Australia Health Workforce Australia Medical Oncology Group of Australia Monash Cooperative Cancer Consortium Private Cancer Physicians of Australia Victorian Cancer Agency: Cancer 2015

Cabrini Monash University Department of Medicine

stablished in 2006, the Cabrini Monash University Department of Medicine provides a focus for research and education in medicine within Cabrini. The major stream of research relates to the translation of research evidence into medical practice and improvement in models of care for our patients. We are particularly interested in research as it relates to the care of the elderly and in particular end-of-life care.

agreed format and rules of engagement. The thesis was submitted in September 2014 by PhD student Alice Rouse. Long-term health outcomes in patients aged over 80 years after an intensive care unit (ICU) admission This prospective study aims to determine health outcomes for patients aged 80 years and older, including quality of life and functional status, up to two years after

Current projects Clinician patient discourse â&#x20AC;&#x201C; a multimodal investigation This qualitative study aims to describe how the work of the ward round is carried out communicatively and to investigate whether there are distinctive characteristics of communicatively effective ward round interactions. Analysis of the data shows that the ward round communication is a stylised conversation with a particular

From left: Associate Professor Michele Levinson. Associate Professor Michele Levinson (Head of the Cabrini Monash University Department of Medicine and general physician) during a ward round with doctors Justin Cole, Chris Yeo, Michael Rose and Kelvin Kuik.

discharge from intensive care. The 24-month follow-up was completed in October 2014. Preliminary findings are that quality of life is maintained post-ICU admission. We have explored motivations, satisfaction with outcomes and factors affecting medical decision-making in the group of patients (80 years and older) who had cardiac surgery (Oldroyd et al 2013). Frailty and relationship to length of hospital stay This study was completed by Dr Hanmei Pan as a registrar project and showed that frailty is a better predictor for discharge destination than age. Dr Pan is now a consultant geriatrician at Monash Health. End-of-life care projects Our work on end-of-life care addresses the topic in a number of different ways. We have written on attitudes towards dying and how the concept of death has changed over the course of history. A medical science approach

to defy death is not always helpful in preparing for the imminent death of a loved one (Gellie et al 2014, Mills et al 2014). Also, we have written on the default response to in-hospital cardiac arrest, which is to attempt resuscitation except in the presence of a do-notresuscitate order. We argue that resuscitation status for all elderly patients should be discussed and actively decided on admission to hospital (Levinson and Mills 2014.)

We conducted a multicentre, point prevalence study to investigate the number of advance care plans and not-forresuscitation orders across five Victorian health services (with the manuscript in preparation). Completion of this study revealed each site had its own set of forms and policies regarding resuscitation status, which combine to contribute to barriers to the writing of do-not-resuscitate orders (Levinson et al 2014). A 12-month retrospective review of medical emergency team (MET) call data in 2012 illustrated the role of the MET in end-of-life care, especially with regard to writing limitations of treatment orders. This review will be extended by inclusion of data from 2013. We have investigated the use of language around concepts of resuscitation. A pilot study, and now a group of elderly, hospital-admitted patients, were surveyed to assess understanding of terminology relating to ‘do-not-resuscitate’ orders. The next step is to survey elderly people who live in the community.

Future projects Planning is underway for projects that will investigate a description of the illness trajectory over 12 months in a post-acute hospital admission in the elderly; the utility of the ‘surprise question’ in predicting inpatient mortality; and surveys of clinical staff regarding their attitudes and understanding of resuscitation. Education Our involvement in the government-funded Specialist Training Program continues and includes two advanced trainees in general medicine and one in intensive care /general medicine. This has been a successful

Clockwise from top: Dr Hanmei Pan, a geriatric registrar, spent six months at Cabrini working on a collaborative research study about frailty. Dr Amber Mills is a Research Fellow in the Cabrini Monash University Department of Medicine. A study that illustrates the role of the medical emergency team (MET) in end-of-life care is being extended by inclusion of data from 2013. Pam Pendleton (a critical care nurse) is pictured with Dr John Reeves, Director of Cabrini’s intensive care unit.

Cabrini Monash University Department of Medicine

program with excellent feedback; it has been accredited by the Royal Australasian College of Physicians for General Medicine training for each of the participating registrars. Two trainees participate in inpatient and

ambulatory care within the Professorial General Medical Unit and under the supervision of one of three consultant physicians working on a rotating roster with designated medical receiving days via the emergency department. Training supervision is provided by Associate Professor Levinson. An additional trainee in the general medical stream participates in an intensive care rotation under the supervision of Associate Professor Levinson and Dr Jonathan Barrett. Our registrars participate in curriculum development for the clinical school and are involved with the research program of the Cabrini Monash University Department of Medicine. The Department of Medicine and associated clinical service delivery unit (Professorial General Medical Unit) place a high priority on the mentoring of undergraduate medical students and postgraduate trainees. Many of our undergraduate students continue to return for further rotations and postgraduate placements.

Above: Dr Jonathan Barrett (Deputy Director, Intensive Care) is pictured with Nurse Manager Jill Saville.

Leadership positions and appointments As well as her Cabrini commitments, Associate Professor Levinson has held the following leadership positions, appointments and commitments during 2013-14: • Member of SAC for Acute and General Medicine • Lead in Accreditation • Co-Chair RACP-CICM Working Group on Joint Training • Site visit for trainee/site in trouble • OTP interviews for RACP • Examiner for FRACP clinical examination • Represented SAC at RACP Education Committee meeting 2013 • Represented SAC at the Advanced Training Forum 2014 Dr Mills, in addition to her role as Research Fellow at the Cabrini Monash University Department of Medicine, is a Board Member of the Australian Patients Association, which is an independent, not-for-profit organisation dedicated to championing and protecting the rights and interests of all patients.

Matt Johnson TEAMWORK FOR BETTER CLINICAL EDUCATION

att Johnson, former Manager of the Simulation Centre and now Director of

Clinical Education, is clear that at Cabrini, education isn’t about “time served” by the clinician, it’s about quality of care – improved patient safety. “It’s not about the time spent educating, it’s about patient outcomes. There’s a real appetite to keep improving,” says Matt. “That means lots of simulation activities and experiential learning”. “For example, in the emergency department where we’ve held deteriorating patient workshops, we know that when adverse events occur, they mostly occur because of time pressure and communication breakdowns,” says Matt. “Simulation activities highlight this and show how changes in behaviour can translate into differences for patient outcomes. As a patient deteriorates, how does the team work together? What can we learn from this and how do we change?” ‘Team’ is a word that Matt uses a lot. At Cabrini, clinical education has shifted from traditional approaches (ward-based, discipline-specific education) to teambased training involving diverse groups of clinicians. “Logistically, it can be difficult to do, but it’s universally well accepted and well received, the notion that it is how we work together, so that’s how we should learn,” says Matt.

Cabrini Centre for Nursing Education and Research

Nursing research at Cabrini is focused on excellence in patient and family care. We aim to constantly improve and evaluate the safety and quality of our services, provide evidence for nurses to inform their clinical practice and help our patients and their families make informed healthcare decisions. The new Centre for Nursing Education and Research has been established at

Cabrini, in order to help us achieve our goals. This chapter includes the research activities of the centre while our education activities are reported in the chapter entitled ‘Clinical education at Cabrini’. This is the first report of the Cabrini Centre for Nursing Education and Research. The goals of this centre are to:

• Develop a culture of clinical enquiry • Develop subject matter experts 4. Support quality improvement research and disseminate findings through conference presentations and publications

1. Evaluate Cabrini nursing safety and quality activities

5. Work with Cabrini’s organisation development function in building a learning organisation at Cabrini

2. Assist Cabrini in addressing the National Safety and Quality in Health Service (NSQHS) Standards of Care evaluation criteria

6. Build our reputation in the key areas of patient experience, safety and quality of patient care and other areas

3. Build the research capacity of nursing at Cabrini, in order to: • Provide a resource for evidence; data collection methodology and interpretation; and evaluation • Develop research skills within the workforce by supporting the research training of staff and encouraging staff with ideas to develop into junior researcher practitioners

7. Develop a research program in the area of nursing leadership, workforce and skill development

From top: Associate Professor Leanne Boyd. Nurse Stephanie McArthur with a cardiac patient at Cabrini Malvern.

Progress in 2013-14 A Research Associate has been appointed to support the Director who commenced in July 2014. A research agenda has been established and approved which is based on the Cabrini Strategic Plan 2013-15 and aligns with the (NSQHS) standards evaluation requirements.

A highlight was the enhanced level of postgraduate enrolments and research dissemination among the Cabrini education team. The supervision of higher degree research students reinforces the research culture at Cabrini and our success with publications is demonstrating growth in this area. We are currently working to establish: • A student support hub to provide assistance and resources for nursing staff undertaking postgraduate degrees

• Research partnerships with universities and other stakeholders

Applicants: Boyd L, Cosgrave M, Goh J, Warren T, Brockhus F, Johnson M (2013-14)

• Research expertise in leadership and patient centred care, as well as quality and safety

Commonwealth Department of Health and Ageing (amount: $444, 950) Project title: Improving navigation of Australian drug and alcohol services: mapping and database creation Applicants: Boyd L, Sheen J; Lubman D (2013-14)

• Research secondments where Cabrini nurses who have an interest in research work on a project while working part-time clinically. The aim is to enhance individuals’ research skills and embed them within the practice setting. This will expand our local research capacity and support the development of a culture of enquiry in our workforce. Grants The following grants were awarded in 2013-14. Victorian Department of Health (amount: $145,000) Project title: Evaluating the national standards education projects using a process and impact evaluation strategy

Australian Catholic University/HWA fund (amount: $24,100) Project title: Mapping placement capacity and quality Applicants: Boyd L, Spence A (2014) Australian Catholic University/HWA fund ($28,367) Project title: Developing the preceptor role within Cabrini Applicants: Boyd L, Spence A (2014)

From left: Nurse Stephanie McArthur with a cardiac patient at Cabrini Malvern. Research Associate Amanda Pereira-Salgado has joined the Cabrini Centre for Nursing Education and Research. Nurse Yvonne Youngs, wearing protective clothing as she tends patient Douglas Gordon.

Cabrini Monash University Department of Surgery The Fröhlich West Chair of Surgery

stablished in 1998, the Chair of Surgery at Cabrini Hospital is a joint venture between Cabrini Institute and Monash University. It was the first of its kind in the Victorian private medical sector and one of the first in Australia. The chair was endowed as the Fröhlich West Chair of Surgery in 2004.

participate, making this one of the most broadly accepted database models in the world. The first major publication from the database was accepted in Diseases of the Colon and Rectum, demonstrating the highest ever reported level of clinician compliance with data entry: a critical marker of success for measurement of clinical quality.

During 2013-14, the Cabrini Monash University Department of Surgery continued to play a critical leadership role in bowel cancer research, public education and awareness of bowel cancer screening. This year saw the appointment of Dr Simon Wilkins as Inaugural Post Doctoral Research Fellow. His appointment as a fulltime researcher in the department has provided greatly enhanced research output in 2014. A highlight was the successful roll-out of our department’s database to both our Monash Partner hospitals and bi-nationally as the database of the Colorectal Surgical Society of Australia and New Zealand (CSSANZ). More than 70 centres have signed up to

From left: Associate Professor Paul McMurrick. Associate Professor Paul McMurrick farewells medical evacuee Kingsford Guri (PNG) following successful surgery and treatment at Cabrini Malvern (photo by Janine Eastgate, courtesy Leader Community Newspapers). Colorectal surgeon Mr Stephen Bell performs surgery at Cabrini.

This year saw the introduction of meetings of MONCARP, a bowel cancer research partnership led by our department and incorporating our clinical partners at other Monash University affiliated hospitals and researchers from the Faculty of Medicine. Our public awareness campaigns have seen important partnerships formed with the Jodi Lee Foundation, Austereo MMM and the AFL’s Collingwood Football Club. Major public awareness initiatives are planned for 2015, in order to try to improve on the modest levels of public take-up of the National Bowel Cancer Screening Program. In late 2014, we will host a visit by Professor George Chang from MD Anderson Cancer Centre, as our 2014 AL Polglase Visiting Professor in Surgery. Professor Chang will speak on the topic of ‘Colorectal cancer in the younger population’ at Cabrini Malvern. Doctors, nurses, allied health practitioners, staff and others are invited to attend.

During 2013-14, we continued to host rotating SET 1 trainees in surgery and we welcomed Boris Ruggerio as our Colorectal Fellow. We maintained representation on representative boards and learned bodies as follows: • Joint Council of Monash Comprehensive Cancer Consortium and Southern Melbourne Integrated Cancer Service: Associate Professor Paul McMurrick • Executive Committee, Cancer Stream, Academic Health Science Centre, Monash Partners: Associate Professor Paul McMurrick • Executive Council, Victorian Clinical Oncology Group: Associate Professor Paul McMurrick • Member of the Training Board in Colon and Rectal Surgery: Mr Stephen Bell • Member of the Victorian Advisory Panel for the National Bowel Cancer Screening Program: Mr Stephen Bell

Clockwise from top: Dr Simon Wilkins is Inaugural Post Doctoral Research Fellow: a full-time research role which benefits the department’s research output. Cabrini colorectal surgeons are pictured performing surgery (middle) Associate Professor Paul McMurrick and (bottom) Mr Peter Carne.

Clinical education at Cabrini

abrini is a strong supporter of education in healthcare through the Cabrini Clinical School, which coordinates, manages and promotes clinical education and research within Cabrini. Cabrini is a teaching hospital. In fulfilling this role, we participate in undergraduate and postgraduate education in allied health, medicine and nursing. Medical education During 2013-14, Cabriniâ&#x20AC;&#x2122;s medical education program continued to expand. The number of students and doctors (who voluntarily give their time to teach in all areas of anaesthesia, medicine, pathology and surgery) continued to grow. The continual expansion of the medical education program reflects its strong reputation. Undergraduate education For the 2014 academic year, 24 third-year students are placed at Cabrini under the direction of Associate

Professor Michele Levinson who is Clinical Dean. During the year, mentoring tutor groups continued, as well as our successful interdisciplinary learning program. Our bedside teaching and learning activities continued, as well as involvement of our postgraduate trainees in the education and mentoring of our undergraduates. Development of the online portal on the Cabrini website continued, which provides access to the undergraduate education program. Students are now able to complete an online orientation to the program prior to clinical placement. In 2013-14, we increased our numbers of fifth-year students. It is pleasing to see our third-year students returning to Cabrini for their fifth-year placements. We continue to provide placements for fourth-year students in paediatrics. We are extremely thankful to our patients and their families for their valued contribution to medical education at Cabrini.

From left: Associate Professor Michele Levinson (Clinical Dean). Anne Spence (Manager, Education)

Postgraduate education The Commonwealth Department of Health and Ageing funds specialist training positions. This provides specialist trainees with opportunities to experience medical practice in the private sector, which is an important provider of medical care in the community. These positions were awarded to Cabrini in conjunction with public health services, including Alfred Health, Eastern Health, Monash Health and Peter MacCallum Cancer Centre. We offer positions in a wide range of disciplines including colorectal surgery; emergency medicine; general medicine (three positions); geriatrics; haematology; intensive care; medical administration; medical oncology; neurology; palliative medicine; pathology; and upper-gastrointestinal surgery. The specialist trainees participate in patient care, audit and research at Cabrini with guidance and supervision of consultant physicians and surgeons.

We are enjoying our purpose-built education precinct, which provides an excellent venue for the ongoing education of our health workforce. The simulation centre has allowed the development of an integrated simulation and problem-based learning curriculum for third-year medical students, which is valuable. We are planning to integrate inter-professional education over 2014. Changes in clinical education There were some major changes in education at Cabrini over the past year. Organisationally, nursing education joined medical and allied health education to form the Cabrini education department under the auspices of the Cabrini Institute. This has identified a number of opportunities in education planning and has fostered inter-professional teaching and learning activities. A highlight was the opening of the Patricia Peck Education and Research Precinct. The building houses the Cabrini

Institute, which leads Cabrini’s work in education, research and health promotion. This is now Cabrini’s permanent base for students and clinical researchers. In its first full year, it is anticipated that 500 students will participate in clinical education there and more than 600 clinicians will conduct education, training and research. Undergraduate and postgraduate students from medicine, nursing and allied health are supported in their learning through the simulation centre. The centre focuses on enhancing patient safety, excellence in patient and family care and interdisciplinary teamwork. A number of pilot studies are underway, which will enable situational learning to be embedded within all Cabrini campuses.

• Introduction of version six of the Cabrini learning management system (LMS) • Introduction of a student portal for all disciplines containing EQuIPNational education material (note: EQuIPNational is a four-year accreditation program for health services designed to ensure a continuing focus on quality and was developed in response to the Australian Commission on Safety and Quality in Health Care’s National Safety and Quality Health Service Standards which are mandatory for health services from 1 January 2013)

Other developments and work in progress over 2013-14 include:

We have continued our relationships with Deakin University (CADET model) and Australian Catholic University (ACCENT model) in the provision of undergraduate nursing placements. Also, we expanded our capacity to support Monash University Masters of Nursing Practice students at Cabrini Brighton.

• A review of the undergraduate nursing program • A review of the Cabrini graduate nurse program • A review of Cabrini postgraduate nursing programs

Undergraduate nursing placements

From left: Cabrini’s new Patricia Peck Education and Research Precinct at 154 Wattletree Road, Malvern. Chief Executive Dr Michael Walsh speaks at the official opening and blessing of the Patricia Peck Education and Research Precinct held in November 2014. Then Mayor of Stonnington Councillor Matthew Koce experimented with simulation technology when he toured the Patricia Peck Education and Research Precinct.

Clinical education at Cabrini

Graduate programs 26

The Cabrini graduate nurse program continues to flourish. Currently we have 46 graduate nurses with seven of them undertaking their graduate year within the perioperative environment. Allied health education Allied health education has become integrated as part of the Cabrini Centre for Allied Health Research and Education, enabling us to move toward an overarching strategic plan linking staff research and education. Development in several aspects of staff and student education programs has progressed over the past 12 months, with focus on finalising the Clinical School Network Agreement with our primary university partner, La Trobe University. This will enable undergraduate student placements in the disciplines of dietetics, occupational therapy, physiotherapy, social work and speech pathology to be formally coordinated and

supported within this agreement, together with the support provided by La Trobe University appointed Associate Professor in Allied Health Dr Helena Frawley and a Student Placement Clinical Coordinator. Plans continue for student placements with other university providers in speciality areas or postgraduate placements. Development of an online allied health student portal has progressed, in order to meet the specific needs of allied health students and their clinical supervisors. Cabrini continues its partnership with Holmesglen TAFE, teaching into Holmesglenâ&#x20AC;&#x2122;s Certificate IV in Allied Health Assistance, as well as accepting clinical placement of the Holmesglen Certificate IV Allied Health Assistance Course Students. A mapping exercise has been introduced, in order to track staff postgraduate qualifications and professional development activities. This is designed to ensure identified priority service areas are met with the highest levels of skills. Currently allied health staff

Above: Matthew Johnson is pictured in the Stewardson Charitable Trusts Simulation Centre at the Cabrini Institute.

have access to professional development opportunities, which are well subscribed. However, we hope to seek opportunities to offer more substantial and regular funding support through the development of scholarships and other avenues of support to formal learning and higher qualifications. Simulation Centre Since it opened in February 2014, the Stewardson Charitable Trusts Simulation Centre has conducted more than 300 simulation activities involving 714 students and staff. The simulation activities have focussed on undergraduate nursing and medical students entering clinical placements at Cabrini, providing them with supervised opportunities to improve their skills in basic life support, communication with patients and identification of the deteriorating patient. Research generated from these activities has resulted in acceptance of oral presentations at three national

conferences and two international conferences. The simulation activities have extended into the hospital setting at Cabrini Malvern, now being conducted regularly at the wards. A partnership with Laerdal Australia has seen new technology that enables real-time tracking of performance and automated feedback implemented on a trial basis at Cabrini Malvern. The next year will see an expansion of simulated learning activities both in the simulation centre and at all Cabrini campuses. Library The Lee & Brian Johnstone Library is the new library space, which has become an integral part of education and research at Cabrini. Staff and students use the physical library space to engage in group learning, silent study, and training in information skills via formal and informal library sessions. The Cabrini Library Collection Development Policy was revised in January 2014, in order to develop and

plan for an increase in electronic resources that can be accessed and discovered by all staff across all Cabrini sites. Increased funding has allowed subscriptions to more bibliographic databases and purchase of e-book content to over 100 titles, as well as subscribed and open-access to more than 6000 online journals . Through promotion of the library and its services, it has become a collaborative partner in the information requirements of clinical, research and non-clinical areas of Cabrini. This is reflected in increased use of the libraryâ&#x20AC;&#x2122;s services and resources. Statistics show that literature search requests increased by 15 per cent. There was a large increase of 82 per cent (17,960) in full text articles downloaded by staff. The e-library will extend beyond the hospital environment in 2014 with the purchase of OpenAthens Software, which will allow staff and specialists access to the its resources from home or a mobile device.

Above: Di Horrigan is Cabriniâ&#x20AC;&#x2122;s librarian based at the Patricia Peck Education and Research Precinct.

Education infrastructure 27

The education infrastructure team has worked on simplifying systems to support an increasing number of clinical placements. We are standardising agreements and building stronger relationships with fewer education providers. Our main providers are Monash, Deakin and Australian Catholic universities. We aim to ensure that our excellent education provision is underpinned by a sustainable business model. We support the Specialist Training Program and have 20 posts in partnership with public hospitals across a wide spectrum of specialties at Cabrini. Trainees value the opportunity to learn from and work closely with our medical consultants. We have secured funding for two additional positions in 2015: one in gastroenterology and one in general medicine. These trainees provide wonderful support to our undergraduate medical education program.

Cabrini Monash Psycho-oncology

he Cabrini Monash Psycho-oncology group, established in 2008, strives to achieve real clinical research outcomes that can make a difference to people’s lives. We work to conduct best practice, evidence-based research, clinical interventions and education with respect and understanding. Awards Dr Sue Burney’s contribution to health psychology and psycho-oncology was recognised by the Australian Psychological Society with the following honour: Australian Psychological Society, College of Health Psychologists, Award of Distinction 2013.

Chief Investigator: Associate Professor Mark Frydenberg, Faculty of Medicine, Nursing and Health Sciences, Monash University

• Holding a range of psycho-education workshops for Cabrini’s cancer patients and their families at our Brighton and Malvern hospitals

Education

• Provision of a clinical psychological service in the day oncology units at our Brighton and Prahran hospitals

In the second half of 2013, we supervised one student from Victoria University and two Doctor of Psychology (Health) students from Deakin University on placement with the group. In the first half of 2014, we continued with the two Doctor of Psychology students. We began supervision of one clinical master student from Australian Catholic University and one counselling master student from La Trobe University.

Research grants

As part of these placements, students are involved in a range of experiences such as:

Victoria Cancer Agency, Collaborative Research Grant ($2m) Project title: The Cancer of Prostate Translational Research in Victoria (CAPTIV) Collaboration

• Conducting a mindfulness program for patients, families and staff at our Brighton, Malvern and Prahran hospitals

Above: Dr Sue Burney

Clinical services The Melbourne Psycho-oncology Service continues to be led by Jane Fletcher, who is the treating psychooncologist and health psychologist. It operates at three Cabrini locations and a monthly session is held at Australian Urology Associates. The service provides support to carers and family members and those who have been bereaved through cancer. During the year, Cate Miach was appointed to expand the practice and decrease waiting times. Dr Burney and Ms Fletcher continue to provide a consultation psycho-oncology service at Cabrini Prahran.

Dr Burney, who works part-time as a psychologist at Cabrini Prahran, has introduced a range of supportive care strategies at this hospital. Ms Fletcher and Ms Miach provide psychological input in the eight-week breast cancer rehabilitation program. Engagement in the professional community Dr Burney continues to be actively involved with the Australian Psychological Society College of Health Psychologists (Victoria). She and Ms Fletcher have continued to work on the update of the National Health and Medical Research Council’s Clinical Practice Guidelines for the Psychosocial Care of Adults with Cancer. Dr Burney was also involved in the CareSearch palliative care project. Ms Fletcher and Dr Jo Brooker are committee members of the Mental Health Professionals Network, Psycho-oncology Group. Dr Brooker is a member of the Cabrini Human Research Ethics Committee.

Current projects

Completed research projects

• Finding the Words: The lived experience of parents in communicating their cancer diagnosis to their children • The lived experiences of patients and carers in Cabrini’s palliative homecare service • The development of a treatment decision-making aid for patients who have early stage, non-small cell lung cancer • The development of a treatment decision-making aid for men who have early stage prostate cancer • The unmet needs of women diagnosed with ovarian cancer • Understanding and measuring health literacy for caregivers of people who have cancer • Refinement and revalidation of the demoralisation scale • Meaning and purpose therapy in advanced cancer – a pilot, randomised, controlled trial • Self-compassion and psychological health: the mediating role of emotion regulation difficulties

• Exploring the factors predicting psychological distress in haematopoietic stem cell transplant patients • Post-traumatic stress and post-traumatic growth in women diagnosed with ovarian cancer • The information and supportive care needs of Australian, Greek and Italian men diagnosed with early stage prostate cancer • An exploration of the experiences of volunteers in the Cabrini biography service • The impact of physical activity on the psychological wellbeing of men undergoing androgen deprivation therapy • The lived experience of women who have gynaecological cancers • Oncology patient wellbeing: mood, quality of life, and fatigue

From left: Key staff and students of the Cabrini Monash Psycho-oncology group. Jane Fletcher (Deputy Head) is a psycho-oncologist who works in clinical practice.

Allied Health Research Unit

his is the second report of the Allied Health Research Unit, which was established in 2012 to build the research capacity across and within each of Cabrini’s allied health professions. During 2013-14, Cabrini’s Allied Health Research Unit operated for its first full 12 months. It is led by Associate Professor Helena Frawley under a joint appointment with La Trobe University. This has been an important development in allied health research at Cabrini, as we enter a formal agreement with our new university partner to support research and education in allied health throughout the organisation.

While the allocation for allied health research is a small, part-time fraction, it is anticipated that the unit’s activity and output will grow over time to become a productive and leading centre for allied health research in private healthcare. Research activity has progressed over the past 12 months and for the first time, this has been captured in an allied health research activity database. The research findings

Leadership of the unit has been supported by other research-active staff: • Tash Brusco, Manager of Physiotherapy Services, who is currently completing her PhD • Dr Rosemary Higgins, health psychologist

From left: Dr Helena Frawley PhD FACP. Allied health therapies are integrated into patients’ care plans where appropriate.

highlight the depth and breadth of research activities among allied health clinicians and will support plans to identify strengths and any deficits in staff research expertise, in order to meet our strategic research goals and support improvements in patient outcomes. Several research projects are in consultation and design phase, with interest in multidisciplinary collaboration and focus on delivering research outputs that align with our goals. A second focus of allied health research activity is translating research into practice. Implementation of findings from research is the critical step to directly improve clinical practice and outcomes for patients. Activities to support this include review of current clinical practice guidelines to ensure the highest levels of evidence inform allied health clinical practice. Associate Professor Frawley is working with department managers to achieve this goal. In itself, this activity is supporting allied health research capacity and capability.

Staff representing most allied health disciplines and across all Cabrini campuses have been active in research projects, with outputs ranging across CHREC-approved research projects, publications, grants, conference presentations, translational research and quality improvement activities. Research projects Allied health research support is directed to projects led by the dietetics department and a multidisciplinary allied health rehabilitation project. The projects are as follows: 1. To identify the risk and prevalence of malnutrition in colorectal cancer patients from diagnosis to 30 days post surgical intervention. Lead: Marlene Gojanovik (dietetics) 2. Investigating Malnutrition in Victorian Cancer Services – Point Prevalence Study 2014. Lead: Elizabeth Kent (dietetics) 3. International Nutrition Survey 2013. Lead: Elizabeth Kent (dietetics)

4. A multidisciplinary rehabilitation program for patients following surgery for colorectal cancer. Lead: Helena Frawley (allied health). Disciplines involved: physiotherapy, health psychology, occupational therapy and dietetics. This project has a nested pelvic floor muscle measurement study, which is in collaboration with the University of Melbourne and is part of a student’s PhD study. Publications As Cabrini-based allied health research is nascent in its development, no CHREC-listed research projects have translated to publications yet but this is expected to eventuate in the next 12 months. Despite this, researchactive allied health staff feature in two publications in 2013-14 with Cabrini listed as an author affiliation, thereby contributing to the profile of allied health clinical research at Cabrini.

From left: Tash Brusco, Cabrini’s Manager of Physiotherapy Services, is active in research and currently completing her PhD. Libby Kent, Cabrini’s Manager of Nutrition and Dietetics, is leading two research projects related to nutrition.

Grants 31

During 2013-14, two research-active staff have been successful in attracting external funding which will support their research activity: 1. Dr Helena Frawley, NHMRC Health Professional Research Fellowship 2014-17 2. Dr Rosemary Higgins, who received several project grants from the Victorian Cardiac Clinical Network and BeyondBlue to support her research programs. Conference presentations Over the year, allied health staff were active in conference presentations with research topics covering an extensive range of healthcare areas relevant to Cabrini. Presentations from staff include those invited as experts in their field and those selected during blinded peer-reviewed processes, across State, national and international events.

Health promotion

he Cabrini Institute supports health promotion activities on behalf of Cabrini. Cabrini is committed to enhancing health and quality of life by treating sickness and by working with our patients, residents and their families to anticipate, prevent and ease suffering. Let’s Beat Bowel Cancer Let’s Beat Bowel Cancer (LBBC) is a not-for-profit health promotion initiative of Cabrini, designed to lower deaths related to bowel cancer – also known as colorectal cancer – via public awareness, research and medical advances.

Our key goals for Let’s Beat Bowel Cancer are to: • Demystify bowel cancer and increase awareness of bowel cancer as a major public health issue • Encourage every Australian 50 and over to screen regularly for bowel cancer • Promote and support ongoing bowel cancer education and clinical research, focusing on prevention, early detection and treatment of bowel cancer Through LBBC, Cabrini remains committed to ongoing bowel cancer research and raising awareness of the importance of bowel screening in order to achieve better health outcomes for our community. We continue to work to raise awareness among all Australians that while bowel cancer is the second-biggest cause of cancer-related death in Australia, it is preventable. Early detection with regular screening is vital to a positive outcome with excellent success rates of approximately 90 per cent. Unfortunately less than 40 per cent of cancers are detected in the early stages.

Although bowel cancer screening is one of the simplest and most effective methods for the prevention and early detection of bowel cancer, latest reports show that participation rates for bowel screening in Australia are declining. This is concerning and there remains much to be done to beat bowel cancer in our community. The LBBC program supports the clinical bowel cancer research activities of the Cabrini Monash University Department of Surgery, led by Associate Professor Paul McMurrick. Our activities are supported by the LBBC Fundraising Committee, which raises vital funds to support the initiative and bowel cancer related activities at Cabrini, including: • Bowel cancer health promotion activities • Bowel cancer research activities

From left: Supporters of Let’s Beat Bowel Cancer (from left): Associate Professor Paul McMurrick (colorectal surgeon and head of the Cabrini Monash University Department of Surgery), Dr Peter Lowthian (Executive Director, Medical Services), Emeritus Professor Adrian Polglase and Des Jackson (member of the Let’s Beat Bowel Cancer Committee). The Art Series Hotel Group is platinum sponsor of the Let’s Beat Bowel Cancer Golf Classic.

• A Colorectal Fellowship program, which supports research and the training of the future colorectal surgical workforce • Equipment related to bowel cancer management LBBC health promotion activities Bowel cancer is preventable and treatable, yet Australia has one of the highest rates of the disease in the world. The need for greater awareness and resulting behavioural change towards prevention and early detection in the community remains as important as ever. For the second year in a row, Let’s Beat Bowel Cancer partnered with Bowel Cancer Australia for our annual and largest national media campaign to date. Strategic communication support for this national campaign promoting bowel screening for all Australians aged 50 and older was provided by Haystac (a division of the Aegis Media Group).

In 2014, the campaign previously known as FOBruary underwent rebranding and creative refreshment. A new positioning line ‘Don’t Be a Fool. Test Your Stool’ put a fresh, light-hearted touch on what is an otherwise serious campaign. Mass media activity was focused in mid-February 2014, with national advertising conducted over January-March 2014. The campaign was designed to achieve awareness and understanding of bowel cancer prevention and the benefits of bowel cancer screening. The advertising message was promoted in outdoor advertising, newspapers, online, magazines, television, radio and cinemas, as well as in pharmacies, clubs and community groups across Australia. Advertising helped to generate traffic to a dedicated campaign website www.testyourstool.org Ambassadors have always formed an integral part of LBBC bowel cancer campaigns. They act as high profile spokespersons and help to generate media coverage

and participation. In 2014, we were fortunate to have the support of George Negus, Michael Caton, Sophie Scott, Anton Enus, Geoff Cox (known as Coxy), Daryl Somers OAM and Kevin Sheedy. Highlights from the 2014 campaign include: • Radio community service announcement with voiceover provided by veteran news reporter and author George Negus • New animated television commercial with voiceover by Sophie Scott, ABC Radio health reporter • Young & Jackson digital advertising billboard (timed to coincide with Melbourne’s White Night Festival) • $238,000 in pro bono support from the Aegis Media Group (an increase of $20,000 on last year) • $894,000 media value received (an increase of $169,000 on last year)

From left: A luncheon was held in April 2014 to recognise Golf Classic sponsors and supporters; Lindsay Fox AC spoke at the event. The ‘Don’t Be a Fool. Test Your Stool’ message was featured on the digital advertising billboard above the iconic Young & Jackson Hotel in Melbourne.

Health promotion

Campaign supporters

Playing to save lives

Aegis Media Group (Haystac, Mitchell & Partners, Posterscope, Jumptank) BowelScreen Australia Channel 31 Cancer Councils of Australia Clinical Genomics (formerly Enterix Australia) Fairfax Community Newspapers and Radio King & Wood Mallesons News Australia (Leader Community Newspapers) Network Ten Pharmacy Guild of Australia Royal Australian College of General Practitioners SBS Television and Radio Southern Cross Austereo Network SEN Radio Val Morgan Cinema Network Yahoo!

The ninth Let’s Beat Bowel Cancer Golf Classic was held in 2014 at Kingston Heath Golf Course. Sponsors and guests enjoyed 18 holes of golf, excellent food and beverages, as well as a range of inspiring and informative speakers and special guests. As Let’s Beat Bowel Cancer’s key fundraising event, the event has been successful and received strong support due to loyal and generous sponsors and donors. The event is managed by the Let’s Beat Bowel Cancer Committee in collaboration with GOLFSelect,

A field of 91 players teed-off helping to raise approximately $80,000. The event included ‘Beat the Pro’ and ‘Hole in One’ competitions, as well as an on-course barbecue and refreshments. The event finished with dinner, a fundraising auction and prize presentations. The Proclaim team, led by Jon Broome, took winning team honours for the second consecutive year. Logical

Above: Television celebrity Geoff Cox (known as Coxy) is an ambassador for Let’s Beat Bowel Cancer. He is pictured at the Golf Classic event held annually since 2005 to raise awareness and funds to support the cause.

Staffing Solutions, led by Russell Hutchinson, was close second. Anthony Panuzzo and Emma Bryan were the winning individuals. The Let’s Beat Bowel Cancer Committee thanks platinum sponsor The Art Series Hotel Group, as well as all gold and silver sponsors for their generous support. Platinum sponsor The Art Series Hotel Group Gold sponsors Anderson Partners BDA Marketing and Planning Commonwealth Bank Garuda Indonesia Identity Matters K2 Asset Management Kay & Burton

Logical Staffing Solutions Morgan & Griffin McMurrick Family Pan Pacific Hotels Group RMBL SouthEast Business Park UBS Special luncheon A special luncheon was held on 2 April 2014 to thank Golf Classic sponsors and key supporters of the event. Thirtytwo guests attended a candid discussion with trucking magnate and supporter of Let’s Beat Bowel Cancer Lindsay Fox AC. Associate Professor Paul McMurrick gave an overview of the latest bowel cancer research agenda at Cabrini. The lunch was hosted by Des Jackson, Chair of the Golf Classic Sub-Committee, in the UBS Wealth Management Boardroom in Melbourne.

Recognition and appreciation Cabrini’s Let’s Beat Bowel Cancer initiative relies on the generosity of the community through philanthropic support to achieve the program’s goals, as we do not receive any government funding. The ongoing success of Let’s Beat Bowel Cancer is due largely to the commitment and enthusiasm of dedicated committee members who continue to work hard in approaching potential and existing sponsors about fundraising activities. The Cabrini Institute is grateful for their efforts. We are indebted to our patrons, ambassadors, corporate sponsors, suppliers and philanthropic donors for their generous support and ongoing commitment to helping us beat bowel cancer. Foundation 49: Men’s Health Foundation 49: Men’s Health (also known as F49) is an initiative of Cabrini designed to improve the health of

From left: John Allen (Council member Foundation 49: Men’s Health), Penny Christie (Manager Foundation 49: Men’s Health), ambassador Nic Stirzaker and Dr Peter Lowthian. Associate Professor Gary Richardson and the Honourable Jeff Kennett AC.

Australian men. We do so by raising awareness of health issues and encouraging men to have regular checks. This is done through the distribution of information, as well as supporting local communities and health professionals. In 2013-14, program staff and supporters had a busy year promoting men’s health and wellbeing throughout Australia. GP Symposium The Foundation 49: Men’s Health GP Symposium was held on 12 April 2014 at Cabrini’s Patricia Peck Education and Research Precinct (154 Wattletree Road, Malvern). Eleven top specialists provided participants with current information, diagnostic and treatment strategies in the contemporary setting. It was attended by more than 50 general practitioners, health professionals and medical students.

Health promotion

Men’s Health Business Breakfast

Whole New Ball Game

Community grants

The Foundation 49: Men’s Health business breakfast was held on 11 June 2014 at Melbourne’s RACV Club and it coincided with International Men’s Health Week. Supported by the Cabrini Foundation and convened by John Allen (F49 Council), the event attracted 280 guests (50 more than last year). The keynote speaker was the Honourable Jeff Kennett AC who spoke about maintaining good mental health and wellbeing and his work with Beyondblue.

Foundation 49: Men’s Health continued to publish its men’s health magazine A Whole New Ballgame. Three editions were published and distributed, each with a print run of 10,000 copies. The magazine covered a range of men’s health topics and issues including: cancer and conditions specific to men; risk and prevention; and technological advances that support health.

The Men of Malvern ‘good men doing good things’ are supporting F49 with funding to assist with the community grants program for 2014. We are currently facilitating 16 grants for this round. They will support community groups throughout Australia to hold men’s health events and other activities to raise awareness of the importance of men’s health.

Men’s Health Toolkit

Workplace health education sessions

Panellists included Aboriginal Olympian Kyle Vander Kuyp, barrister Greg Barns, television personality Brad McEwan (who was Master of Ceremonies) and Australian Defence Force squadron leader Aaron Ward.

The program’s key resource is a booklet called the Men’s Health Toolkit. It is distributed throughout Australia on request. It is a popular resource, which provides information and support for men encouraging healthier lifestyle choices.

Foundation 49: Men’s Health has continued to offer educational sessions in the workplace, providing a tailored presentation to groups of male employees that are both informative and fun. These have been well received and we are working to enhance this program with the aim of encouraging better health behaviours in the workforce.

Communications Various communications are issued under the Foundation 49: Men’s Health banner. They are designed to promote and encourage men’s health and wellbeing.

Website There is a dedicated website for Foundation 49: Men’s Health. Funding has been allocated for an upgrade to the site www.49.com.au

Above: Penny Christie, Manager Foundation 49: Men’s Health, spoke at a number of events over the year.

Kingsford Guri NEW LIFE FOR KINGSFORD

ingsford Guri (27) of Papua New Guinea had life-changing surgery in 2013-14, thanks to

Cabrini and the Children First Foundation. He was treated as a medical evacuee under Cabrini’s social outreach program. For all his life, Kingsford suffered from Hirschsprung’s disease. It was recognised early and at two months of age, he was treated at a hospital in the PNG highlands where he had a colostomy bag fitted. Kingsford’s disability prevented him from living normally, as he had no access to the plastic bags needed to collect waste from his colostomy. “Kingsford’s life was very hard,” says Associate Professor Paul McMurrick who is a colorectal surgeon at Cabrini, head of the Cabrini Monash University Department of Surgery and member of the Let’s Beat Bowel Cancer Committee. “Stigmatised due to his disability, Kingsford had been unable to complete his education or live a normal adult life.” Associate Professor McMurrick and Mr Chris Kimber (paediatric surgeon) assessed Kingsford, in order to plan the best approach to Kingsford’s surgery. “In November 2013, Kingsford underwent a major surgical procedure at Cabrini Malvern to remove the diseased parts of his bowel; then he had further surgery in January 2014 to remove the colostomy,” says Associate Professor McMurrick. “He is now doing very well: the difficulties he has endured are now behind him.”

Kingsford Guri (centre) with Taissa Usatoff (left) and Jose Borje, who volunteered their time to assist with Kingsford’s operations.

Department staff

Monash Department of Clinical Epidemiology at Cabrini Hospital Head of Department Professor Rachelle Buchbinder Administrative Assistant Lavonne Collins Managing Editor, Cochrane Musculoskeletal Group Dr Renea Johnston ARAD State Coordinator Joan McPhee Biostatistician Dr Margaret Staples Research Fellow Dr Allison Bourne Postdoctoral Research Fellow Dr Susan Slade Research Assistant Marshall Mrocki PhD scholars Megan Blackburn (2010-), Deakin University Rebecca Jessup (2014-), Deakin University Sarah Hosking (2014-), Deakin University Dr Bethan Richards (2011-), University of Sydney

Louise Sparkes (2013-), Monash University Masters students Kelly Joyce (2014-), Monash University BBiomedSci student Shehzaad Muhammad Peerbux (2014), Monash University Cochrane review medical students Jessica Deitch (Monash University) Edward Oâ&#x20AC;&#x2122;Bryan (Monash University) Michael Silagy (Monash University) Stephen Surace (Monash University) Sabbaticals Professor Francis Guillemin (Nancy University, Nancy, France) Professor Clermont Dionne (Laval University, QuĂŠbec, Canada) Cabrini Monash University Department of Medical Oncology The Szalmuk Family Department of Medical Oncology Head of Department Associate Professor Gary Richardson Principal Investigators Dr Yoland Antill Dr Ben Brady

Dr Andrew Haydon Dr Melita Keneally Dr David Pook Professor Miles Prince Associate Professor Gary Richardson Dr Jeremy Shapiro Dr Michelle White Associate Investigators Emma Beadsley Dr Sanjeev Gil Associate Professor Ian Haines Dr Henry Januszewicz Oliver Klein Esther Lin Dr Lara Lipton Dr Ben Markman Joanna Morgan Dr Nicole Potasz Professor Max Schwarz Dr Robert Stanley Karen Taylor Associate Professor Max Wolff Research Manager Barbara Scher

Study coordinators Julia Carlson (team leader) Jaishri Ellengovan Mary Lane Jenny McIndoe (Cancer 2015) Alice Newman Helen Smenda Finance Manager Janine La’Brooy Family Cancer at Cabrini Lynne McKay

Volunteers Valerie Co (fifth-year medical student) Natalie Heriot Dr Annie Walker (as fifth-year medical student) Monash Medical Centre, Alfred Hospital and Royal Melbourne Hospital third- and fourth-year medical students for the point prevalence study Cabrini Centre for Nursing Education and Research Director Associate Professor Leanne Boyd

Cabrini Monash University Department of Medicine

Research Associate Amanda Pereira-Salgado

Head of Department Associate Professor Michele Levinson

PhD scholars Louise Alexander: What are the impacts of simulation based education and training on healthcare trainees attitudes towards the mentally ill? Janet Curtis: Occupational health and safety issues within the paramedic workplace Matthew Johnson: Impact of communication education on students’ communication skills in clinical practice Grainne Lowe: Nurse Practitioner policy and future directions

Research Fellow Dr Amber Mills Research Assistants Anthea Gellie Gaya Sritharan Gemma Stephenson Higher Degree Research Students Alice Rouse, PhD student

Tegwyn McManamny: The role of primary healthcare in the management of dual-diagnosis patients within Australia Diana Wong: A comparative analysis of evaluation models used in disaster responses Masters students Jo Miller Emma Patterson Amanda Peat Chris Quinn Jo Schlieff Tanya Warren Bachelor of Nursing (Honours) student Meg Pollock Cabrini Monash University Department of Surgery The Fröhlich West Chair of Surgery Head of Department Associate Professor Paul McMurrick Academic staff Emeritus Professor Adrian Polglase Mr Stephen Bell Mr Roger Berry Mr Peter Carne Mr Martin Chin

Department staff

Mr Chip Farmer Mr Pravin Ranchod Mr Andrew Smith Administrative and management staff Jane Makin – Manager Let’s Beat Bowel Cancer Karen Oliva – Database Manager Dr Simon Wilkins – Research Fellow Clinical Education at Cabrini Director of Education Associate Professor Leanne Boyd Allied health education Associate Professor Helena Frawley Tash Brusco, Manager Physiotherapy Services/Education Portfolio, Cabrini Allied Health Committee Simulation Manager Matt Johnson Manager of Library Services Diane Horrigan Nursing education team Fiona Barker Agnetha Clarke Andrew Driver (maternity relief) Lauren Felsinger (maternity leave)

Elizabeth Gherardin Yvette Gomez Abby Hadden Claire Hatherley Natalie Horvath Michelle Kirwood Julianne McKernan Jo Miller Judith O’Neill Christine Quinn Sharon Rubeli Joanne Schlieff Elizabeth Smith Louise Suttie Tanya Warren

Administration team Barbara Miles Maria Terzoglou

Clinical liaison team CADET program: Tanya Warren, Cathie Muling ACCENT program: Louise Buchhorn, Emma Patterson

Deputy Head Jane Fletcher

Education infrastructure team Anne Spence (Manager) Anne-Marie Devine Jan Palich Sue Smith

Medical education Clinical Dean Associate Professor Michele Levinson Administrative assistants Elizabeth Hopkins Claire Weeden Cabrini Monash Psycho-oncology Head of Unit Dr Sue Burney

Research Fellow Dr Jo Brooker Current research students Rebecca Carlson, Graduate Diploma of Psychology, Deakin University Melissa Maas, Doctor of Psychology (Health), Deakin University

Brindha Pillay, Doctor of Psychology (Clinical), Monash University Sophie Robinson, Doctor of Psychology (Clinical), Monash University Lyndel Shand, Doctor of Psychology (Health), Deakin University Gemma Stephenson, Bachelor of Psychology (Honours), University of New England Adriana Ventura, Doctor of Psychology (Health), Deakin University Eva Yuen, PhD, Deakin University Allied Health Research Unit Head of Department Dr Helena Frawley PhD FACP Associate Professor Allied Health, La Trobe University, Melbourne.

Health Promotion People behind LBBC Let’s Beat Bowel Cancer Committee Richard Morgan AM (Chair) Dr Peter Carne Andrew Facey Des Jackson (Chair, Golf Classic sub-committee) Sue James Dr Peter Lowthian Associate Professor Paul McMurrick Geoff Stansen Retirement from committee Pamela Darragh Patron Emeritus Professor Adrian Polglase Manager Jane Makin Golf Classic Event Manager Samantha McLennan

People behind Foundation: 49 Men’s Health Manager Foundation: 49 Men’s Health Penny Christie Foundation 49 Council Associate Professor Gary Richardson (Chair) John Allen Robyn Charlwood Penny Christie Mr Jeremy Grummet Dr Daryl Kroschel Associate Professor Doug Lording Professor Bernie Marshall Alistair McCreadie Stephen Mead Dr Peter Wirth

Governing safe and ethical research

Supporting ethical research

he Cabrini Human Research Ethics Committee helps to protect the interests of patients, researchers and Cabrini by maintaining high ethical research standards in research projects. High quality, ethical research creates many benefits for patients, health professionals and the community. The Cabrini Health Human Research Ethics Committee reports directly to the Cabrini Board. It reviews and approves research projects conducted at Cabrini that involves human participants. It is chaired by Dr Margaret Staples and managed by Anne Spence.

Above: Anne Spence (Manager, Education).

Our Human Research Ethics Committee ensures that:

Activity

• Ethically sound research is promoted and supported at Cabrini • The research affirms the mission and values of Cabrini and social teachings of the Catholic Church • Ethical standards are maintained in research projects to protect the interests of the research participants, the investigator and the institution

During 2013-14, the Cabrini Human Research Ethics Committee (CHREC) worked on 116 projects. These projects included receipt of 89 new projects and final approval of 85 projects. This is a significant increase on the 64 projects approved in 2012-2013. We have more than 990 projects in our HRECTrack database. It is interesting to compare the data for the year under review with the period five years ago. At that time, we approved about the same number of projects but the profile of those projects was very different. We had 36 pharmaceutically sponsored studies in 2008-09 compared with 14 in 2013-2014. We have seen growth in investigator-initiated studies. The biggest change is in the number of documents requiring approval as part of the studies. In 2008-09, we reviewed and approved 1136 documents compared with 2012 documents in 2013-14. That represents an increase of 77 per cent over the five years.

It operates in accordance with the National Statement on Ethical Conduct in Research Involving Humans issued by the National Health and Medical Research Council in 2007, other relevant Commonwealth and State legislation and regulations and Catholic Health Australia’s Code of Ethical Standards for Catholic Health and Aged Care Services in Australia.

The CHREC continues to be led by Dr Margaret Staples. In 2013-14, we welcomed Drs Bronwyn Sacks; Dane Horsfall and Associate Professor Val Usatoff (Deputy Medical Director Cabrini) to our membership. A highlight was a twilight seminar held on 29 May 2014 to educate staff on the new Australian Privacy Principles, including related governance of clinical registries. Of particular interest was information related to the privacy provisions around data stored outside the Australian privacy laws. The session was presented by Simon Bailey and Dr Heather Wellington from DLA Piper. Certification The National Health and Medical Research Council’s National Certification Scheme of Institutional Process (related to the ethical review of multicentre human research) conducted an audit of Cabrini’s processes in December 2013. We received recertification from 1 January 2014 until 31 December 2016.

Cabrini Human Research Ethics Committee 45

Name

NHMRC category

Gender

Status

Dr Dane Horsfall

Professional carer

Male

Started 27/2/14

Dr Bronwyn Sacks

Professional carer

Female

Started 27/2/14

Associate Professor Val Usatoff

Researcher

Male

Started 27/2/14

Dr Michael Ben-Meir

Professional carer

Male

Finished 8/1/14

Frances Brockhus

Additional

Female

Finished 12/4/14

Emma Patterson

Professional carer

Female

Finished 22/5/14

Professor Miles Prince

Researcher

Male

Finished 8/1/14

Beatrice Bastomsky

Lay person (female)

Female

Michelle Britbart

Lawyer

Female

Dr Joanne Brooker

Researcher

Female

David Curtain QC

Lawyer

Male

Associate Professor Henry Debinski

Researcher

Male

Revd Kevin McGovern

Pastoral carer

Male

Associate Professor Marilyn Poole

Additional

Female

John Robertson

Lay person (male)

Male

Anne Spence

Invitee

Female

Dr Margaret Staples

Chairperson

Female

Dr Sharon Woolf

Professional carer

Female

Supporting ethical research Research Area

Title

Principal Researcher

Arthritis

Standardised method for reporting exercise programs

Dr Susan Slade

A double-blind, randomised, placebo-controlled, dose-escalation, multicentre study of a single, intravenous infusion of allogeneic mesenchymal precursor cells in patients who have rheumatoid arthritis and incomplete responses to at least one TNFÎą inhibitor

Associate Professor Stephen Hall

A multinational, prospective, observational study in patients who have unresectable or metastatic melanoma [CA184143]

Dr Ben Brady

A phase 3, multicentre, open-label, randomised study of nab-paclitaxel plus gemcitabine versus gemcitabine alone as adjuvant therapy in subjects who have surgically resected pancreatic adenocarcinoma [ABI-007PANC-003]

Associate Professor Jeremy Shapiro

A phase 3 study comparing daratumumab, lenalidomide and dexamethasone (DRd) versus lenalidomide and dexamethasone (Rd) in subjects who have relapsed or refractory multiple myeloma [54767414MMY3003]

Professor Miles Prince

A prospective cohort study of patients who have cancer of unknown primary to create a national information resource and improve understanding of the molecular biology, clinical, quality of life and psychosocial characteristics [SUPER]

Associate Professor Gary Richardson

A study into the safety, efficacy and tolerability of scalp cooling for patients receiving chemotherapy in the reduction of chemotherapy-induced alopecia

Vicki Durston

A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial of fulvestrant (Faslodex) with or without PD-0332991 (palbociclib) +/- Goserelin in women who have hormone receptor-positive, HER2-negative, metastatic breast cancer whose disease progressed after prior endocrine therapy [A5481023]

Dr Yoland Antill

Investigating practices relating to malnutrition in Victorian Cancer Services: Cancer Malnutrition Prevalence Survey 2014

Elizabeth Kent (Morrell)

Randomised, double-blind control trial of Megestrol acetate, dexamethasone and placebo in the management of anorexia in patients who have cancer

Dr Esther Lin

The effects of contrast media on methotrexate levels: a retrospective study

Emma Wong

The Lymphoma Lifestyle, Environment and Family study (the LEAF study)

Professor Miles Prince

Cancer

Research Area

Title

Principal Researcher

Cancer continued

A randomised, placebo-controlled, double-blind, phase 3 study evaluating safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in subjects who have early stage, triple-negative breast cancer (TNBC) [M14-011]

Dr Yoland Antill

Understanding how body composition can lead to prostate cancer progression

Professor Mark Frydenberg

The acceptability, feasibility and efficacy (phase II RCT) of a decision aid for men who have localised prostate cancer and their partners

Professor Mark Frydenberg

Circulating tumour DNA as a biomarker in pancreatic cancer

Associate Professor Lara Lipton

A phase 4, randomised, double-blind, placebo-controlled study of continued enzalutamide treatment beyond progression in patients who have chemotherapy-naĂŻve, metastatic, castration-resistant prostate cancer [MDV3100-10]

Associate Professor Jeremy Shapiro

A phase Ib/II, multicentre study of the combination of LEE011 and BYL719 with letrozole in adult patients who have advanced ER+ breast cancer [CLEE011X2107]

Dr Yoland Antill

Patient Discharge Survivorship Improvement Project

Amanda Proposch

The effects of butyrylated high amylose maize starch on polyposis in familial adenomatous polyposis patients

Professor Finlay Macrae

Complete pathological response after neoadjuvant radiotherapy for rectal cancer and its relationship to the degree of T3 invasion

Mr Stephen Bell

A retrospective audit of lung cancer diagnostic and treatment intervals across the Southern Melbourne Integrated Associate Professor Gary Richardson Cancer Service region with a pilot study of locally approved referral interval target times A multinational, phase 3, randomised, double-blind, placebo-controlled efficacy and safety study of Enzalutamide in patients who have non-metastic castration resistant prostate cancer

Associate Professor Jeremy Shapiro

Development of a Patient Symptom and Care Management Diary

Amanda Proposch

Evaluation of the implementation of follow-up phone calls for patients after receiving cycle 1 of chemotherapy treatment and patientsâ&#x20AC;&#x2122; experience of pre-chemotherapy education session

Amanda Proposch

Evaluation of patient satisfaction and comfort at the Cabrini Malvern Day Oncology Unit

Amanda Proposch

Supporting ethical research Research Area

Title

Principal Researcher

Cancer continued

A phase 3, randomised study of BBI608 and best supportive care versus placebo and best supportive care in patients who have pretreated advanced colorectal carcinoma

Associate Professor Jeremy Shapiro

A three-arm, randomised, open-label, phase 2 study of everolimus in combination with exemestane versus everolimus alone versus capecitabine in the treatment of post-menopausal women who have estrogen receptor positive, locally advanced, recurrent or metastatic breast cancer after recurrence or progression on prior letrozole or anastrozole

Dr Yoland Antill

A phase 3, multicentre, randomised, double-blind study to compare the efficacy and safety of oral azacitidine plus best supportive care versus placebo plus best supportive care in subjects who have red blood cell, transfusiondependent anemia and thrombocytopenia due to IPSS lower-risk myelodysplastic syndromes

Dr Melita Kenealy

A phase 3, randomised, double-blind trial of Pegylated Liposomal Doxorubicin (PLD) plus AMG 386 or placebo in women who have recurrent, partially platinum sensitive or resistant epithelial ovarian, primary peritoneal or fallopian tube cancer

Associate Professor Gary Richardson

Epidemiology of multiple myeloma in Australia study

Professor Miles Prince

Brightways breast cancer database

Associate Professor Gary Richardson

Sternal bleeding during coronary artery bypass surgery

Mr Randall Moshinsky

Reducing red blood cell transfusion in cardiac surgery: a multicentre, quality improvement initiative of the Perfusion Downunder Collaboration

Mr Michael McDonald

Heart Failure Model of Care

Katherine (Kate) Steen

Impact of age and frailty on care and outcome of acute coronary syndrome in the elderly

Dr Swati Mukherjee

To identify the risk and prevalence of malnutrition in colorectal cancer patients from diagnosis to 30 days postsurgical intervention

Elizabeth Kent (Morrell)

Assessing compliance of texture modified diets and thickened fluids provided to patients in a rehabilitation setting (in comparison to current standards).

Rebekah Scholes

Comparison of clinical reasoning ability of medical students using in a problem based learning structure

Matthew Johnson

Cardiology

Dietetics

Education

Research Area

Title

Principal Researcher

Education continued

Implementation and evaluation of changes to the Cabrini corporate orientation program and local induction processes

Anne Schultz RN

An impact evaluation of NSQHS standards

Associate Professor Leanne Boyd

The safety and use of intravenous Metoprolol in general hospital wards â&#x20AC;&#x201C; a single-centre, observational study

Dr Diane Kelly

2014 Extension to Cabrini emergency department scribe pilot trial

Dr Katie Walker

Cabrini emergency department scribe study

Dr Katie Walker

Does anti-androgen therapy impair cognitive function in women who have polycystic ovarian syndrome?

Professor Susan Davis

Endocrine Surgery Unit Databases and Thyroid Cancer Registry

Dr Simon Grodski

An open-label extension and safety monitoring study of moderate to severe ulcerative colitis patients previously enrolled in etrolizumab phase 3 studies [GA28951]

Associate Professor Henry Debinski

A phase 3, double-blind, placebo-controlled, multicentre study of the efficacy and safety of Etrolizumab during induction and maintenance in patients who have moderate to severe active ulcerative colitis and who are refractory to or intolerant of TNF inhibitors [GA28950]

Associate Professor Henry Debinski

A phase 3, international, multicentre, randomised, double-blind, placebo-controlled, parallel-group efficacy and safety trial of Linaclotide administered orally for 12 weeks to patients who have irritable bowel syndrome with constipation

Associate Professor Henry Debinski

Genetics

Integration of genetic testing for risk associated genomic variants and rare predisposition genes into the management of high risk hereditary breast cancer families

Dr Yoland Antill

Gynaecology

A prospective, non-randomised, parallel cohort, multicentre study of the Solyx single-incision sling system versus the Obtryx II sling system for the treatment of women who have stress urinary incontinence

Dr Anna Rosamilia

Haematology

Improving Management by Participatory Research In Oncology: the Victorian Experiment (the IMPROVE study)

Professor Miles Prince

Infection control

Nursing-led antimicrobial stewardship intervention pilot project on the documentation of antimicrobial therapy in haematology and oncology patients

Associate Professor Mary Oâ&#x20AC;&#x2122;Reilly

Infectious diseases

Patient attitudes towards immunisation for healthcare workers in a private day oncology unit

Dr Jason Goh

Emergency medicine

Endocrinology

Gastroenterology

Supporting ethical research

Research Area

Title

Principal Researcher

Intensive care

TRANSFUSE: sTandaRd issue trANsfusion versuS Fresher red blood cell Use in intenSive carE-a randomised controlled trial

Dr Jonathan Barrett

Medical imaging

Tailoring 99mTc MAA doses to reduce radiation burden to patients for nuclear medicine ventilation perfusion scans

Sarah Gales

Medicine

Validation of a hospital-in-the-home specific patient satisfaction instrument

Ian Campbell

A non-invasive screening tool for anaemia

Associate Professor Michele Levinson

Models of care

Staff perceptions of the effects of a changed model of care in a palliative care service

Dr Natasha Michael

Nursing

Patient Safety Falls

Kirsten Seletto

The impact of an undergraduate university fellowship program on the perceptions of work-readiness among new graduate nurses: A cross-sectional study

Emma Patterson

Pilot study of the ‘Breast Feeding Champions’ group

Chris Quinn

Evaluation of the Cabrini situational learning project

Associate Professor Leanne Boyd

INtroducing A Care bundle to prevent pressure-point injury (the INTACT trial)

Professor Tracey Bucknall

Cabrini intensive care advanced life support refresher and team training using simulation course research project

Elizabeth Gherardin

Recognising and responding to patient deterioration education program

Elizabeth Gherardin

An impact evaluation of the paediatric life support learning unit

Associate Professor Leanne Boyd

Listen to me, I really am sick! Understanding patient and family perspectives in triggering responses to medical emergencies

Professor Tracey Bucknall

Review of the Cabrini graduate nurse program

Associate Professor Leanne Boyd

Patients’ and nurses’ preference for patient participation in safety activities

Professor Tracey Bucknall

Cardiac Foundation Program

Elizabeth Gherardin

Research Area

Title

Principal Researcher

Nursing continued

What are patientsâ&#x20AC;&#x2122; perceptions of medication management during their hospitalisation?

Unknown

Evaluating the Malvern Nurse Manager orientation and induction process

Margaret Harley

Obstetrics

Australasian Maternity Outcomes Surveillance System (AMOSS): improving the safety and quality of maternity care in Australia

Dr Danielle Wilkins

Ophthalmology

Retinal oxygen levels and laser therapy for central retinal vein occlusion