Edition 20: Person of the month - Kevin Smith by cannabisworldjournals

Editorial and Journalistic Team Cannabis World Journals

Cannabis World Journals is a bi-weekly publication that discusses the latest trends in the cannabis industry.

Content Management:

Alibert Flores. Anne Graham Escobar.

Graphic Design and Conceptualization:

Katerin Osuna Robles. Juliana Cuervo Tibambre.

Research, Journalistic and Editorial Team:

CannaGrow: Daniela Montaña and William Gonzales. CannaCountry: Sandra Loaiza. CannaLaw: Anne Marie Graham, Alibert Flores, and Caterina Lomoro. CannaTrade: Jennifer Simbaña, Lorena Díaz, Verónica Hernández, and Rosangel Andrades. CannaMed: Jennifer Salguero. CannaGraphics: Alibert Flores.

Translation:

English: Sandra Loaiza, Verónica Hernández, and Nicole Gómez. Arabic: Menna Ghazal and Oraib Albashiti. Portuguese: Lorena Díaz. Italian: Caterina Lomoro.

Collaborators in this edition:

Educación Cannábica Argentina Caucannabis

Subscribe at cannabisworldjournals.com Info@cannabisworldjournals.com

EDITORIAL:

OP-ED COLUMN:

- My Plant… My Dream… My Right. Pg. 4

- Cannabis Use After the War. Pg. 5

- Educación Cannábica (Cannabis Education). Pg. 7 - Caucannabis. Pg. 7

8 24

CANNAGRAPHICS:

CANNAGROW - Self-cultivation: A Social Right with International Perspectives. Pg. 8

IN THE EXPERT'S ROOM: - Colombian Cannabis Lawyers. Pg. 10

Our magazines, CannaMed and CannaLaw, dedicated to the therapeutic area of cannabis and the legal regulation area of cannabis, respectively, have decided to join forces to offer you a new, more complete bi-weekly cannabis magazine: Cannabis World Journals. CannaMed magazine and CannaLaw magazine became sections of Cannabis World Journals. Along with them, you will discover two new sections to offer a global look at the plant's market. We are talking about CannaTrade, whose objective will be to reveal the rhythm of the businesses around cannabis, and CannaGrow, dedicated to the botanical cultivation of the cannabis plant. Cannabis World Journals is the most comprehensive cannabis magazine for discerning readers like you. Without further ado, a warm welcome to you.

CANNACOUNTRY: - South Africa. Pg. 15

CANNALAW - Malta: A Precedent for Italy. Pg. 17 - Debate: Stripping Cannabis of its Unjust Criminalization. Pg. 19

- Cannabis, Minorities, Prison, Money and YOU. Pg. 21

PERSON OF THE MONTH -

Kevin Smith. Pg. 24

CANNATRADE - The Best Ideas to Get Started in a Growing Industry. Pg. 31 - How Does Cannabis Affect the Global Economy? Pg. 33 - Cannabis and the Work Environment. Pg. 35 - Diverging Realities: Unaffordable Pricing of Medical Cannabis. Pg. 38

CANNAMED - Medical Cannabis Is a Right for All: How the Communication Between Patient and Healthcare Professional Affects the Prescribing Process. Pg. 42 - Cannabis-based Medication Available on the Market. Pg. 44

EDITORIAL

My Plant… My Dream… My Right. As the years have gone by, one could believe that because we live in modern times, the unrestricted right to medical cannabis is something that concerns us all. Unfortunately, we could not be further from the truth. Although it has been legalized in several parts of the world, in many other places, there are still debates and conferences to achieve its approval. Suppose we were to make astral trips at will to various places on the planet. In that case, we could see and hear the voices of patients who appeal to its use to alleviate pain or those who have resorted to cultivation as support and protection for their families. We could see fighting health professionals who have enabled its use for its extraordinary healing properties. We could also see scientists who every day discover more and more reasons why cannabis is an excellent option for health and claim more possibilities to study the benefits of its consumption. We would have the possibility of listening to the arguments of lawyers who have intervened, defending the free right of people to use the plant as the best health option to alleviate their pain or save their lives. It would be wonderful if everyone could have free access to it without any problem. In this context, the intervention of

legal professionals is vital, either to defend, in criminal proceedings, people who cultivate to collaborate in the care of diseases or to represent those who seek to obtain authorizations to produce or procure that which can appease the pain. When will we stop seeing people who are unjustly arrested just for having medical cannabis crops in their homes? When will we stop seeing protests in the streets over petitions for access to cannabis? How many mothers have to fight and cry in the courts so that their children can have the cannabis-based medicine they need so much to alleviate their illness? How much must patients suffer while waiting for cannabis to be granted for their ailment? How many people must be forgotten in prisons for possession of medical cannabis? So many questions only generate more questions that seem to have no answers. How long will we continue to beg for our well-being? At what point did our right to health become so expensive and seemingly unattainable? We urgently request an answer to these concerns that affect us all daily, especially this: Will I ever have the right to consume cannabis? Alibert Flores Editorial Team Cannabis World Journals

CANNABIS WORLD JOURNALS | EDITION NO. 20 |

OP-ED COLUMN

Cannabis Use After the War

It is commonly known that war leaves deep scars on the minds and bodies of those who participate in it. The road is tough and long, endless days that people cannot forget and wounds that remain as mementos of the battles. All these situations are hard to overcome. In general, soldiers, especially in the United States, are often equipped with many tools to cope with everyday life on the battlefield. But it is after the experience that the focus on effective treatment is lost to face the path to follow. What Are the Most Common War Injuries? “Common combat injuries include: second and third-degree burns, broken bones, shrapnel wounds, brain injuries, spinal cord injuries, nerve injuries, paralysis, vision loss, problems of hearing, post-traumatic stress disorder and loss of limbs.” (Brown, 2015). Soldiers as veterans obtain a wide variety of procedures to treat their combat injuries. They have access to doctors, specialists, surgeons,

and physical therapists. Even with all this new arsenal at their disposal, the recovery is lasting, punishing and it usually involves a heavy dose of painkillers. What Are the Traditional Treatments Available? Opioid pain relievers. These are classified as agonists and include Codeine, Darvocet/Darvon, Demerol, Dilaudid, Fentanyl, Hydrocodone, Methadone, Morphine, and Oxycodone, which tend to be quite effective for a certain period until the body generates tolerance to them. These opiates also have a very high probability of developing an addiction and are not the best alternative for treating long-term chronic pain. The opioid crisis is reaching critical levels. “In the United States, 259 million opioid pain relievers were prescribed in 2012, and an estimated 2 million of these people subsequently developed an addiction.” (Addiction, 2021).

CANNABIS WORLD JOURNALS | EDITION NO. 20 |

OP-ED COLUMN

It is vitally important to start looking at alternatives to these chronic pain treatments. What Other Alternatives Exist for Pain Treatment? The treatment of refractory pain and neuropathic pain with cannabis has improved the quality of life of many patients worldwide. It is an efficient alternative to the treatment for chronic pain and at the same time helps to control the symptoms of post-traumatic stress typical of war veterans. Cannabinoid-based therapies can be administered orally, topically, or inhaled in the form of a vaporizer and help reduce anxiety, improve sleep patterns, decrease the perception of central pain, activate the limbic system's reward complex, and act as an agonist at vanilloid receptors.

Many war veterans have found better results in their treatment of chronic pain through cannabinoid-based medical products. It is expected that they will become more widely used as an alternative for treating pain. Unfortunately, there is still too much stigma surrounding its use, and access to cannabinoidbased medications is quite limited.

Organizations like The Veterans Cannabis Project and Veterans for Medical Cannabis Access have taken the lead in this fight to give veterans the freedom to discuss the medical use of cannabis with their doctors without risking retaliation. In countries like the United States, it is also expected to change both federal and state legislation so that access to cannabis products or its derivatives is expanded under the mantle of the law. It is essential to keep these lines of dialogue open to bring to light the benefits of the medicinal use of cannabis and leave prejudice behind. There are hundreds of patients who need alternatives for their pain treatments. Without these alternatives, there is a risk of putting more patients in a situation of vulnerability in the face of possible addiction or overdose of analgesics. Now it is estimated that “83% of US veterans support medical cannabis programs, but none of the Veterans Affairs medical facilities provide medical cannabis as a method of treatment for pain.” (VETSCP, 2021) or any other pathology. María José López Content Editor Pharmacology University INC.

CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaGraphics

Educación Cannábica (Cannabis Education) Educación Cannábica is an academy in Argentina created with the understanding that the training of highly qualified personnel to develop the activities arising from the cannabis production chain is an essential link for the development and progress of the cannabis industry in the region. To date, 400 Growers students have been certified, 35 training courses have been offered, and 4 different specializations are available to be taken through the web portal. The work team comprises a marketing graduate, pedagogues, agricultural technicians and a specialist in networks, and virtual teaching, who are exclusively dedicated to transmitting their knowledge in the best possible way, creating a horizontal, symbiotic and synergistic learning environment. Their conviction about knowledge is that its transmission should be from experience, militating a form of eco-sustainable farming, where collective learning is the protagonist, and we are all on the same side.

Caucannabis Its business development is carried out in Colombia in the department of Cauca, where the CAUCANNABIS Organization was formed, bringing together three crucial companies: A) Caucannabis Colombia, groups 400 associates to legally cultivate in the eventuality when the regulatory framework allows it. B) Caucannabis Medicinal SAS, groups investors from Europe, United States, Canada, Asia, Uruguay, Germany, Holland, among others, companies that in the future will develop different lines related to cannabis: cosmetics, food, medicine; C) Caucannabis Vida Foundation; through it, they have made a research development on the production of medicines and genetics, to treat different ailments like cancer, epilepsy, migraine, liniments, among others. Currently, they treat 900 patients nationwide through magistral formulas.

CANNABIS WORLD JOURNALS | EDITION NO. 18 |

CannaGrow

sELF-CULTIVATION, A SOCIAL RIGHT

wITH International Perspectives Canada, Colombia, Argentina, Chile, Italy, Holland, Israel, and the United States (in some states) have regulated the implementation of self-cultivation for the medicinal use of cannabis. Cannabis consumption in its multiple presentations is increasingly accepted worldwide. Its medicinal use is legal in several countries, which have relaxed their laws to decriminalize its use and authorize an almost 100% legal self-cultivation. Thus, favoring a part of the population that uses cannabis derivatives as a therapeutic alternative in treating health complexities and adult use. Canada, Colombia, Argentina, Chile, Italy, Holland, Israel, and the United States (in some states) have regulated the implementation of self-cultivation for the medicinal use of cannabis. The number of plants is not standard; it varies according to legislative determinations of each country, while in Colombia, a garden of 20 cannabis plants is allowed, in Holland, they only permit five plants.

Countries such as Colombia have one of the most liberal laws in the world regarding the consumption and cultivation of cannabis. It is perhaps an internal cultural secret, where the use of self-cultivation is decriminalized; up to 20 plants can be cultivated (Law 30 1986. Minsalud), producing a boom and several stores specialized in self-cultivation called "Growshops", where supplies, products, and workshops are sold so that those interested are educated in cultivation techniques.

Self-cultivation in Colombia is an example and allows access in an artisanal, natural, and free way to the medicinal compounds of cannabis, considering that, currently, a treatment with phytocannabinoids is expensive. After many CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaGrow of being allowed, only in these times through the current legislation (Resolution 2292 of 2021) the health-promoting entities or EPS (Health Providing Companies) can offer medical formulations based on phytocannabinoids to treat different diseases. Watching the cannabis plant grow and cultivate can be an exciting hobby, where you can learn botany and even electricity. Having your own crop at home for personal consumption contributes socially to not supporting illicit businesses such as drug trafficking.

With home growing, you can produce various products derived from the cannabis plant, from essential oils to edibles, drinks, and medicines. This home production is for personal use only; everything that comes from your garden should be for personal consumption without commercialization. Growing cannabis is like planting any garden plant; you only need basic things like substrate, water, fertilizers, and light. But it is also necessary to have information about the natural processes of the plant and its care. Anyone can grow, but the best quality derives from being attentive to the agronomic practices of the plant, and for that, there is excellent information posted on the net. During the pandemic, the self-cultivation of cannabis was exponential due to the limited access to the products. On the other hand, the illegal situation makes people promote selfcultivation in their homes for empowerment reasons and to know that the product

Having your own crop at home for personal consumption contributes socially to not supporting illicit businesses such as drug trafficking.

consumed was produced organically without contaminating residues. The primary use of cannabis in self-cultivation is perhaps recreational, but it is indeterminable what proportion of consumers are self-supplied and which ones go to the illegal market. Currently, there are learning communities around the cultivation of cannabis in the formalization of a social right in countries with legal regulations on the subject. There is an expectation of widespread social inclusion that acclaims the world civil societies, which should be taken into account by the World Health Organization (WHO). The scientific and academic society worldwide does not propose the legalization of a drug but to comply with the conventions of the United Nations on health, which guarantee the pharmacological use of any natural substance that has therapeutic value Therefore, regulating cannabis would meet the main objective of the international conventions.

In fact, it could be said that it is part of a social phenomenon with cultural, educational and ancestral dimensions, in a scenario in which the international community considers integrating educational proposals regarding the responsible use of cannabis within its public agenda, proposing the legalization and regulation of therapeutic use as a real advance in social inclusion as an international right.

References and Bibliography

MERINO A.(2021) El mapa de la legalización del cannabis en el mundo. https://elordenmundial.com/mapas-y-graficos/mapa-legalizacion-cannabis-mundo/ EL TIEMPO.(15 de diciembre 2021) Los países donde es legal el uso recreativo del cannabis https://www.eltiempo.com/mundo/mas-regiones/en-que-paises-es-legal-la-marihuana-639158 CANNABIS WORLD JOURNALS | EDITION NO. 20 |

Colombian Cannabis Lawyers is a group of lawyers specialized in cannabis issues, foreign investment, tax law, commercial law, and free trade zone. The editorial team of Cannabis World Journals had the opportunity to talk to one of its members, Mr. Henry Muñoz Vallejo, who commented a little about the projects and achievements of Colombian Cannabis Lawyers. CWJ: Tell us, how was Colombian Cannabis Lawyers born? CCL: Colombian Cannabis Lawyers is a law firm in which we process and help international and national companies to process their licenses in Colombia. Likewise, we let them count on us as a Colombian ally, a local ally, where we can connect them with part of the industry and the issue of bank openings. The most important thing with our clients is the opening or applying for the licenses that are processed here. We have processed several important permits, especially for international companies; we also have clients from the United States and Canada. We have also been advising Colombians in several companies and several legal concepts. Colombian Cannabis Lawyers was born out of the country's need to have a specialized sector in cannabis law. That is how we contacted several international lawyers, such as the law firm Hong Law Group, the law firm Vicente Sederberg, and a series of prominent international lawyers with whom we have had international legal relationships. These alliances have helped us position Colombian Cannabis Lawyers not only as a national company but also as a global company. Our primary focus at the moment is not so much the processing of licenses but more of a business approach.

In the

Expert’s Room: Interview with Colombian Cannabis Lawyers A group of lawyers specialized in cannabis issues

CWJ: How interesting, Mr. Henry. At this moment, how do you see the legislative situation in Colombia in relation to cannabis? CCL: In Colombia, since 2016, we have a great legislation, Law 1787. Subsequently, we also had Decree 613, which was the backbone of cannabis for four years. On July 23 of last year, President Duque, in Pesca Cundinamarca, signed Decree 811, which is the one that we are currently waiting for the technical regulation. The Government has just said to sectors such as PROCANNACOL and

CANNABIS WORLD JOURNALS | EDITION NO. 20 | 10

ASOLCANNA that the law is coming this week. The Government announced that in October, the regulation of Decree 811 would come out, which is the one that allows us to export dried flowers and their entry into the free trade zone for packing and repacking of the flower. Likewise, the issue of food use, also in Decree 811, which all the companies are waiting for it. CWJ: This regulation concerning the free trade zone, how does it affect people or companies that are currently working in the industry and for those who want to start working in the industry? CCL: The most important thing is that Decree 811 allows the flower to enter the free trade zone for packing, repacking, and processing. It also allows us to export. Many companies have already started operations in the free trade zone and are waiting for the regulation to come out. What for? To see if they go with a free zone regime in the country or if the law has some benefits to operate in this zone.

CWJ: Thank you very much for the clarification! What is the process that a company in Colombia has to go through to obtain the different Cannabis licenses at the moment? CCL: Analyze whether Colombia has fair or unfair legislation for the activities they want to develop. For example, a Canadian company wants to export dried flowers in 2016. But, in 2016, we could not operate dried flowers, so they would lose the investment. There are approximately 11 to 13 requirements that we need from the companies. Once we have these requirements, after paying the government, we apply for a license. Another requirement that I remember is their cultivation plan, an export plan, a transformation plan, and if they will carry out a transformation or a laboratory. Colombia requires a series of protocols for all the companies that

are very important for them to know, and I imagine that all Latin America is also doing it. Among the requirements, there is the security protocol. That is quite fundamental for companies to be able to operate. It is only needed for psychoactive companies, not for non-psychoactive companies. Still, Colombian Cannabis Lawyers believes that these nonpsychoactive companies should also have a security protocol because there is a lot of capital invested in them. Then, they have to give the payment to the government for the licenses. The most expensive charge is thirty-seven million eight hundred, which is for the psychoactive cannabis license, but the government allows you to pay it in five years. CWJ: Do you think that this generates, to a certain extent, an opportunity for the local market to develop and become more competitive with international markets? CCL: Absolutely! The Government gives us the opportunity, especially for the small and medium growers, the indigenous communities of Cauca, and the communities of the Sierra Nevada. There is a company with a cannabis license: Mama Liliana Pechené. She has a license in Cauca, and she took advantage of this opportunity to pay it in installments. So, this makes these indigenous communities of Cauca also become competitive before the multinationals and before the other companies that already have an economic capacity of more than three billion colombian pesos (US$762.969.536 aprox.). So we believe that there is something competitive, and we believe that one of the few benefits we have today for small and medium growers is this benefit. Although the Government has announced many benefits, we are just starting to see them. CWJ: We know that Colombian Cannabis Lawyers is part of MercoAgrícola and that you also own EXPOMEDEWEED.

CANNABIS WORLD JOURNALS | EDITION NO. 20 | 11

What led you to focus on these different areas of the cannabis industry? Why not limit yourself only to the legal aspect? CCL: Well, in the legal area, we focus on the issue of the processing of the license. In Colombia, there are a series of problems with these licenses. The Government and the legislation say that permits must be processed in 30 days, and at the moment, it is taking two years. So we have seen the need for something faster. From Colombian Cannabis Lawyers, we have started to work on international business, connect companies internationally, do more business because it is faster, and connect Colombian companies with global companies with which we already have significant knowledge and great contact. Why? To try to make negotiations with the companies. MercoAgrícola is a company that has been developing here in Colombia. It is a family company that we have with my wife, Paula Betancur. Paula is the CEO Founder and manager of the CannaWorld Congress and Expomedeweed events. It is an event that we will develop on July 7 and 8 in the city of Medellin. For us, it is a pleasure to announce our new venue, which is Plaza Mayor, the heart of Medellin. Plaza Mayor is the commercial showcase, if not the retail showcase of Colombia and all Latin America. Plaza Mayor hosts countless events throughout the year. CannaWorld Congress is a platform where we bring more than 25-30 scientists to speak on medical cannabis. We have got speakers of the stature of Dr. Lumír Hanus from the Czech Republic, who has a laboratory, Lumir Lab, and who is the discoverer of a substance called Anandamide. Lumír Hanus is the second most influential scientist in the world today, after Dr. Raphael Mechoulam, who we have also had in Colombia via streaming. CWJ: Do you think that the Colombian's vision of cannabis has changed in recent years? And if so, how has it changed? CCL: Everything has been happening since 2016, thanks to the presidential candidate Juan

Manuel Galán, at that time senator, who presented before the Senate of the Republic, before the Congress of Colombia, the Galán Law project or Jacobo Law or Law 80, which consisted in the safe use and access to medical cannabis. Thanks to Juan Manuel Galán, today's country looks at cannabis from another perspective, a medical, scientific, and research vision. We break the taboos that should be developed in the future. Likewise, associations such as PROCANNACOL have been breaking taboos, and we have been, through a serious and responsible way, teaching what medical cannabis is. We also have partners such as the National University and Procannacol. It is very nice what has been developed through associations in Colombia with education through our events. CannaWorld Congress is also an event that focuses 80 or 70% on the issue of education to doctors. That is our strength; we also have some scientists that we bring from Ecuador, Peru, Chile, Uruguay, the United States, Canada. We have had the luxury of getting some lecturers from Slovenia, London, and the Czech Republic. We have a significant educational component, which is the focus we want to develop from CannaWorld Congress. CWJ: There is no doubt that you have a great reach, it's incredible.

CCL: I wanted to let you know that we have two events. Before we did the events in November, we had a six-day one. One day was a business roundtable, two days CannaWorld Congress, and three days Expomedeweed. The platform was top-rated, but no international company could withstand six days of events. Your wife or your family will only wait for you three days or four days, but never six. That's why we split the events into two dates. On June 7 and 8 Canna World Congress and Expomedeweed continues in November, which is a more business component, more commercial, where we have more than 200 stands. Once again, we will be at Plaza Mayor. Before we did it at the Botanical Garden, it was a lovely place, and all the companies liked it; they considered us the most

CANNABIS WORLD JOURNALS | EDITION NO. 20 | 12

beautiful fair in the world. So, this year we will go further because we want to show them the entrepreneurial way. We will show them the entrepreneurial theme to do business so that the companies that have bet on coming to Colombia come to do business. CWJ: What would you consider to be the strengths of the cannabis industry, and how can they position Colombia in front of the world? CCL: At the moment it is Decree 811 and its legislation. Another strength is to take advantage of what Colombia has, the MICC, an internal control mechanism for cannabis, a platform that can help us issue licenses very quickly. Another benefit that we can also take advantage of is the banks, since we can open bank accounts. Colombia already has approximately 2,054 licenses, held by more than twelve hundred companies and they are already becoming very visible at the international level. We have been

famous for the quality of our cannabis that we have grown in previous times, in the Marimbera era. CWJ: Let's talk about a future perspective. Where do you consider your company will be in the next five years?

CCL: Where will our company be in 5 years? Well, Colombian Cannabis Lawyers has represented several companies, especially the company Medical Extractos, a company in the municipality of San Carlos. Medical Extractos currently has the psychoactive cannabis license and has the processing license. The focus is that we will sell THC cuttings and seeds and we are also focused on exporting dried flowers. Colombian Cannabis Lawyers has allied with Medical Extractos to be an essential ally for the issue of international marketing, the point of legal support 100% for that company, and two other companies that have also sought Colombian Cannabis Lawyers.

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Due to the great demand of these companies, we will be there in these years working and supporting Medical Extractos ultimately, especially in their international contacts and international hiring. We have already approached companies from Hong Kong, Germany, Canada, and Latin American companies in Mexico, Peru, Paraguay. We are working very, very hard on international contracts. So that is where we are going to focus with Colombian Cannabis Lawyers and the alliance we have with Medical Extractos. CWJ: Do you have any new projects, any new activities on your agenda for this year? What is in store for you in 2022? CCL: Well, in 2022, we will create two events of international stature. It is a pleasure to announce that the CannaWorld Congress is not only intended for Colombia. At this moment, CannaWorld Congress is an event designed to be a Latin American and international event. We have already been contacted by countries such as Mexico, Peru, and Ecuador to develop CannaWorld Congress together with Colombia. We are looking at the modality of a partnership through franchises to position our event at the Latin American level. That is the most important thing we want to announce. We will have the support of the Government of Antioquia, of the Secretary of Agriculture of Antioquia to make this a reality. We have already had the support of former Governor Luis Pérez and several former governors and several political leaders of Antioquia who have supported us to make this event not a city event but an international event. So that is where we want to focus, on the global theme. Maybe we will also have it in Argentina, and we have been contacted by several important doctors who wish to attend. So it is important to announce it to the world.

CWJ: Well, Mr. Henry, everything you have told us has been very enriching. It is vital to know the scope of this type of event, especially for the industry's growth. The work you are doing is lovely because it is very positive, both legally and in terms of promoting the industry within Colombia. You are giving exposure to small traders and small and medium-sized enterprises locally and internationally because these exchanges with international companies bring growth for everyone. Thank you very much! CCL: Thank you very much. Yes, we believe that doing a fair is to do it responsibly. This year, CannaWorld Congress is following a little bit what NG Business is doing in Las Vegas, which is an event that 4000 companies attend, and they do it seriously. So Colombia is following this platform to position the country and Latin America with its companies, projects, growers, and speakers. So thank you very, very much for this interview to visualize Latin America as a strong group and how you are developing it.

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CannaCountry

South africa

This country on the African continent studied for many years the possibility of legalizing cannabis and finally took the decisive step. The global medical cannabis market was worth $7.8 billion in 2020 and is expected to expand at a compound annual growth rate of 15.3% through 2026.

Right now, South Africa is part of the different countries that have opened their doors to cannabis through its approval for medicinal and adult-use purposes that allow access for everyone in an organized and legal way. Thus, reaching more inhabitants who, either

for medical or personal reasons, wish to have access to the plant Here is a little bit of the present and the future that this African country is planning to have even more access to this industry that wants to reach everywhere. CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaCountry

PRESENT AND PROJECTIONS Africa's most industrialized nation plans to streamline "regulatory processes so that the hemp and cannabis sector can flourish as it does in other countries such as Lesotho," said President Cyril Ramaphosa, in a state of the nation address in Cape Town. This announcement comes after the Department of Agriculture unveiled a strategy for the industrialization and commercialization of the cannabis plant that estimates the size of the local industry at 28 billion rands (approximately US$1.9 billion). This strategy seeks to encourage the cultivation of hemp and cannabis to increase the volumes and variety produced for local and export markets within an effective regulatory system. The global medical cannabis market was worth US$7.8 billion in 2020 and is expected to expand at a compound annual growth rate of 15.3% through 2026, according to research firm IMARC Group. South Africa wants to lean on the cannabis and hemp industry with the idea of creating up to 130,000 jobs and attracting foreign investment as a measure to tackle unemployment currently reaching record highs.

ACCESSIBILITY FOR EVERYONE For many years, the African country studied the possibility of legalizing cannabis and finally took the decisive step to provide access to cannabis derivatives to a larger population through an organized market. That would allow its adequate use for the treatment of multiple diseases that only a few could afford at that time due to its high costs. According to the South African government, the cultivation of medical cannabis aims to provide a standardized and quality-assured product for medical, scientific, and clinical research purposes. They also stressed that "the cannabis produced, as well as any resulting products, will be subject to strict safety and quality control measures." Additionally, it is legal to grow cannabis for personal use in a private place; therefore, it is legal to buy and possess seeds, even for growing cannabis plants. It is also allowed to receive seeds by mail from other countries.

In 2017, cannabis was approved for medicinal purposes, and on September 18, 2018, the Constitutional Court of South Africa effectively decriminalized cannabis for adult and private use.

REGULATION

After cannabis decriminalization, the government has been working on different proposals that could provide greater clarity and control over the use of the plant in various sectors.

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CannaLaw

Malta: A Precedent for Italy The Justice Committee of the Chamber of Deputies approved the Bill which decriminalizes the domestic cultivation of cannabis for personal use.

There are too many aspects in which a population can benefit from cannabis legalization. Legalization represents the opening of a massive door to an industry that is currently booming and growing. It also shows that parliamentarians heard the citizens' voices. Italy has had the cannabis issue under the spotlight for some time now. Especially since September last year, when the Justice Committee of the Chamber of Deputies approved the Bill which decriminalizes the domestic cultivation of cannabis for personal use. It established that the maximum number of plants allowed will be only 4. In the same statement, they proposed a reduction of penalties for minor offenses and an increase of the sentence, from 6 to 10 years, for crimes related to trafficking and possession of cannabis for sale.

This measure is a good sign for Italy, since another member of the European Union that also started with the decriminalization of cultivation was Malta. The Mediterranean country, at the end of 2021, managed to legalize the cultivation and consumption of cannabis for personal and adult use. The archipelago adopted a legal framework regarding cannabis to become a production center for therapeutic purposes, representing economic growth.

In Malta, anyone, who wishes to, may have easy and safe access to cannabis. Users' rights are respected, whether for medicinal or adult use. However, in Italy, despite also being a member of the EU, the situation is different. Partly due to the extreme right-wing parties' conservative and Catholic leanings, which have always opposed and prevented further progress on the issue of legalization.

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CannaLaw

the Italian legislation between legal and illegal cannabis is in their composition. Regarding medical cannabis, demand has increased every year, but according to the Medical Cannabis Patients Committee (Comitato Pazienti Cannabis Medica), 87.5% of patients have had difficulty accessing their prescribed dosage. The demand for medical cannabis has been steadily increasing year after year.

Malta is also a country characterized by being traditionally conservative on social issues. Nonetheless, it was not an impediment for its legislators to achieve in parliament the approval allowing citizens to possess up to 7 grams of cannabis and grow a maximum of four plants at home. With the current Italian regulations, the law 242/16 restricts cultivation and use of Cannabis Sativa. This law specifies that hemp can be used for cosmetics, food, bioconstruction, construction, and textile fibers production.

“In Malta, anyone, who wishes to, may have easy and safe access to cannabis. Users' rights are respected, whether for medicinal or adult use.”

If Italy were to take Malta as a reference in this matter and legalize cannabis, several people would benefit from this measure, especially patients who constantly face the difficulty of accessing their treatment. If cultivation for personal use is approved definitively and without restrictions, it would mean significant change, demonstrating that the Italian Parliament listens its citizens’ requests.

The possession of hemp seeds or plants that do not have this active ingredient is not considered a crime. The percentage of the active principle of THC that is allowed in inflorescences must be minimal. Thus, it must be between 0.2% and 0.5% (with a tolerance of up to 0.6%). Therefore, the major difference established by CANNABIS WORLD JOURNALS | EDITION NO. 20 | 18

CannaLaw

Debate: Stripping Cannabis of its Unjust Criminalization There are many debates on the approval of cannabis for medical use in various parts of the world. If it is carried out, it is considered that it could alleviate problems associated with the illegality of the plant, ending trafficking, violence, and corruption, with public health management that decriminalizes the consumer and decreases the costs of the justice system. That is why the law seeks to establish a framework authorizing governments to harvest, cultivate and

use the plant for the production of pharmaceutical products. The people who are working hard in the informative campaigns of the rights and benefits of cannabis want the plant's legalization to be the first step of a new paradigm in how it is seen in society, but also to strip it of the criminality that its prohibition entails. For this, its legalization would be the first step to a world of regulations that would benefit more than one.

“The law seeks to establish a framework for regulating cannabis for therapeutic, medicinal, or scientific purposes, authorizing governments to harvest, cultivate and use the plant.” “The people who are currently working hard in the informative campaigns of the rights and benefits of cannabis want the plant legalized and stripped of criminality.”

CANNABIS WORLD JOURNALS | EDITION NO. 20 | 19

CannaLaw

However, is the illegal cannabis market growing? After five years of the plant's legalization, California is in big trouble to generate profits. The flexibility of the authorities in the last two decades has favored the black market. According to experts, despite having legalized adultuse consumption in 2016, most of the market is still illegal.

On the other hand, owners claim that high taxes, scarcity of licenses, and regulatory costs in places that do allow trade and cultivation have put the legal market out of reach. That has meant that many entrepreneurs who were supposed to benefit from legalization have ended up losing capital. Meanwhile, consumers are not entirely clear about what is legal and what is not. We can look at the Mexico case, which has had a long road to the approval of

cannabis for adult use. The opinion of specialists agrees that if it is legalized, even if consumption increases slightly due to it, it would be excellent for public health as it has happened in countries like Canada or Uruguay. It would mean that it guarantees quality, and citizens would better evaluate what they consume. However, they see it as complex for legal and illegal production to be clearly separated and for regulatory procedures to work until state institutions enforce the laws.

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CannaLaw You’re living on the street, down on your luck… A man approaches you to buy “weed.” He offers you US$20; you find it and deliver. You get US $5 for getting the job done. Sounds quite simple, to the point, no questions asked. Except he’s a white undercover cop, and you’re black. You are processed under the full extent of the law and eventually receive a life-sentence with no chance of parole. This was the case of Fate Vincent Winslow, who was released after serving 12 years in prison, only to be murdered. Although this is one of the best examples of a gross miscarriage of justice, it’s only the tip of the iceberg…

Cannabis, Minorities, Prison, Money, and

Every day, we live under two completely different realities of the cannabis industry; on the one hand, we have the thriving multi-billion global industry that promises a chance of equality, inclusion, and profits for everyone and, on the other hand, those who have seen its ugly face. Those who are left in the dark, the outcasts, the ones who will never have their share of the ones who will never have their share of the cake, the ones we don’t want to talk about. Let’s get uncomfortable; let’s talk about it. We live in an era of contrast. We celebrate some form of legalization of cannabis in 37 states of the US, where dispensaries are booming. Yet, we deny a license to those who have been convicted and exclude them, even if said conviction is a non-violent cannabisrelated crime that is no longer illegal in said State.

YOU

We praise our evolution with the passing of Bills (S 45 in Delaware, AB 5342 in New Jersey, HB 972 in Virginia) that decriminalize the use of cannabis. Yet, black men are four times more likely than white man

to get arrested for the possession of cannabis, even though statistically both use the same amount (this according to the American Civil Liberty Union data). CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaLaw

We take pride in boosting economies, raising taxes, and providing employment in places such as Colorado, New York, California. Yet, we forget about the legacy industry that still operates in the dark.

We have opened our markets to new cannabis prospects, yet we refuse to expunge the criminal records for those who have served time for crimes now viewed as profitable legal opportunities. We have the laws, we are bettering them each day, but we need to remember what the face of the cannabis industry looks like, who participates in it, not only the legal aspect but those still in the shadows. When this industry was thought of as transitioning from illegal to legal, it wasn’t just about the profits; it was about providing an opportunity for the people who had only known it as a way to make ends meet. However, we have had some recent victories, laws that reflect what we expect and need as a society. To name a few, we mention the Marijuana Regulation and Taxation Act in New York, which protects housing and employment discrimination and addresses other impacts of marijuana prohibition in the areas of immigration and child welfare. It also establishes a licensing system that favors small businesses and farmers instead of large corporations. CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaLaw

We have New Mexico’s Cannabis Regulation Act that protects people against denial of benefits for the use of cannabis, pushes for equity in the new marketplace by allowing individuals with cannabis convictions to work and be licensed, decriminalizes, and eliminates all fines and fees for minors who violate the act. Furthermore, it keeps families together by not taking kids away from parents because of cannabis use. We can expect the MORE act to pass, which would decriminalize cannabis at a Federal Level and seek to expunge prior marijuana convictions so we can repair the extensive damage done to those minorities from decades of biased law enforcement.

It would also establish a federal tax that would be used to assist the communities that have most been harmed from the war on cannabis with programs like job training, substance use treatment, and licensing for cannabis businesses. Although we are getting there, YOU, US as a whole, need to continue to push our legislators to include every aspect mentioned so that we can landscape the cannabis industry we dreamt of as a whole, not the ones corporations have in mind. We need to consider every person, every color, every minority bearing in mind that “no man is left behind.” We are the resistance, the memory, and the initiative that decides “today we create a new industry.”

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Person of the Month

In interview

KEVIN SMITH A staunch cannabis advocate, is making his industry debut with three new strains inspired by his characters Jay and Silent Bob.

CANNABIS WORLD JOURNALS | EDITION NO. 20 |

Kevin Smith rose to fame in 1994 when he directed the film "Clerks" where his most famous characters made their debut: Jay (played by Jason Mewes) and Silent Bob (played by Smith himself). Subsequently, both appeared in the films: Mallrats, Chasing Amy, Dogma, Jay and Silent Bob fight back, and Clerks II. In this edition, the actor, filmmaker, comedian, speaker, comic book writer, author, and podcaster is Cannabis World Journals' guest of honor. Kevin Smith, a staunch cannabis advocate, is making his industry debut with three new strains inspired by his characters Jay and Silent Bob. CWJ: To open up our conversation, I wanted to ask you what is your stance or how do you view the political side of the legalization of cannabis within the United States? How do you view the political situation right now? Kevin Smith: Naturally, I'm a proponent of full legalization. It's delightful that Canada beat us to it. But the fact that we're sitting on a landmass where our neighbors to the north, were always considered more civilized and politer than we Americans down below. It's crazy that they got the legalized cannabis before we did. But as you said, it's political. It's been a lot of people in this country who feel they know what's best for the general populace and have kept it as a Schedule 1 drug for a long time. As we've seen over the course of the last, let's say, five years now, one by one, the states are breaking from that and legalizing on their own. It's wonderful. Problem is, without federal legalization. Banking is really difficult, so this still becomes a cash business only, for most folks who have what are considered legal cannabis dispensaries and cannabis legal states and that's easy pickings for crime. You know, nobody comes at you with a gun: “Give me all your credit card receipts!” But, if you'vegot a cash

register stocked with greenbacks and whatnot, you're sitting duck. That's why when you go into your dispensary out here, like in Los Angeles. Anybody that sells our cannabis, Snoogans, or of course Snoochie Boogie's.

Some of the stores have two armed guards, with vests on just in case things go down. It'd be a lot more helpful and things would kind of calm down considerably if the federal push for legalization would move forward. I'm all for it. So, as much as it's an issue that's fraught with discussion on kind of both sides, I come down on the legalization side. In a world where we have sickening amounts of liquor stores on every corner; and nothing good comes from booze, maybe an hour of good times for you and then misery for the rest of the world. Because, who likes a drunk? Drunks are volatile. You never walked into a cannabis bar and saw a fight. Nothing wrong with a bunch of people getting access to something that chills them out, relaxes them and has medicinal benefits has been proven over the course of the last couple of decades. CWJ: But, legalization has always had a two-edge to it. Because you can you can sell and you can grow. But, there's a limit to how much you can grow. There is a limit on the THC. There's also an understated illegitimacy within the banks themselves, so, most people go crypto. So, it's not really fully legalized right now. What's your stance on that? Now, you're an entrepreneur with your new brands. What has been your input on that double-sided legalization? Kevin Smith: I mean, look for a businessperson, I'd feel a lot better about being in the cannabis business if I didn't think that in any moment the government could come crashing through the door. You know, we feel protected in a cannabis legal state like California, but literally at the end of the day, if the federal government wants to create a problem, it can. And that makes it tough for would be investors or people that want to get into the field without complete federal legalization, which I'm all for as well. It’s a tricky business to be in, which is such a shame because it is legal where I live. You know, I'm not trying to do this in a state that doesn't want it. I'm only talking about the state

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where I live, where cannabis is legal and some of the other cannabis legal states that the Caviar brand is available. They are an incredible gold standard cannabis. Basically, the way I always describe it as: “caviar products are the ones that you use if you're a stoner, a legitimate die-in-the-wool-seven-days-aweek-365-days-a-year stoner. Because cannabis is incredible. It's a proprietary process by which he infuses it with oil. CWJ: When you talk about Caviar, those are the pre-rolled, right? Kevin Smith: Yes. And they also make me moon rocks that you could buy and break them down yourself as well. But, I started using them a couple of years ago and fell in love because I use everything and anything. I used to think I was a Sativa person, but my body processes Indica and Sativa the same way. As long as the cannabis is good. And so, I get to a point where you can use so much. My job allows me to use as much cannabis as I possibly want and can, so it can get to the place where you're not really getting that feeling anymore. But as a 51-year-old man, I get centered. So, in a quest to find some product that would like, give me that feeling that I had when I started using cannabis, I went into a dispensary, and found this brand, Caviar. I fell in love with them, started using it on a regular basis. They have this “Cavichallenge”, like a little video-thing, where if you could use one of their products in 15 minutes, they'd give you a free box. I was: “I'll do that!”- I couldn't do it in 15 minutes, but I met the people there. They were like: “You should talk to Caviar Mike, since you're such a fan of his stuff.” I sat down with Caviar Mike. He told me his story. He was a guy who did not respond to dispensary cannabis anymore. He was like: “I got to figure out a process by which I can make cannabis that'll get me there.” And he did. He created this caviar process, which is amazing. I said, “Look, we're making this movie “Jay and Silent Bob Reboot.” In it, Jay and Silent Bob have three strains of cannabis: Snoogans, Snoochie Boogie and Berzerker. Can you guys make that for us?” And we got in business together, and, he created three different cannabis profiles. One is an Indica, one a Sativa and one is the hybrid. But each one has a different flavor profile to it. Like the Sativa one

tastes like maple, it's like breakfast because we were trying to make three products to last throughout the rest of the day. So, it's been an interesting ride in the cannabis business so far. Educational, to say the least. For those who were like, “Hey, man, like I want to get in the cannabis business because you could be a billionaire.” Well, I don't know who the billionaires are. I've not met them. It's not to say that there's no money. Of course, there's money, and it's lovely money, especially for what it is. It's making people happy, and it's not like this false happiness from some chemical that they come up with in the lab or like a drug or something like that. It's not the false happiness of alcohol and stuff. Is all natural. This was a wildflower that grew on the ground everywhere. It was probably meant to be ingested because you have cannabinoid receptors in you. That kind of availability, to put that in the hands of everybody. Watch everybody chill out across the board. CWJ: At the moment that you've created your brand, how was the process of developing the team? Did you get to learn about the different compounds of cannabis that were involved? What was the process of developing these mutations? Kevin Smith: When I sat down with Mike, it wasn't scientific, it wasn't mathematical. It was him going: “What do you want it to taste like?” I said, “What do you mean?” And he's like, “Look, we got three different strains. They can all have flavor profiles to them as well.” So, he's like, “in the infusion process it’s going to have a taste to it. What would you like it taste like?” And I was like, “Well, I guess, the first use of the day is to wake up. So, if that could

taste like breakfast”. He came back two weeks later with a product like this one, and he was like “Use it, tell me what you think.” I took a hit and I was like, “Wow, man, what is that? It's like syrup.” He's said, “it's maple. It's a maple profile, breakfast!” I said: “I love it!” And the Sativa through his infusion process allows you to lift the THC level of each product. It was more potent Sativa than most. I think it had like 35 or 38 percent THC in his first shot at it. So, with that one, I was like, “Oh, that's lovely. What's next?” He's like, “Well, if we start with breakfast, we

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should do lunch and we should do dinner.” It just kind of made sense. For dinner we came up with the taste of the Snoogans, it is a kind of dessert-afterdinner taste. When you use it, it has this sweet, almost cherry flavor. CWJ: At the beginning it was very controversial because when you started developing content, the stoner content was not something that was very lightly viewed upon. It was seen as a criminal type of activity, the stigma just laid on. When you started developing every movie that you made, it helped take some of the stigma off from people who use it, be it for adult-use or medicinal use. How has that impacted your life? Do you feel that you've shed some light on the industry? Kevin Smith: I think early in my career, I used stoners, particularly Jay and Silent Bob, as comic relief, and all I did was play into the old stereotypes: “Oh, they're silly, they're just stoned, so they're not that bright, and blah, blah, blah.” They get into adventures. But they were kind of typical stoners, so to speak. I wasn't a stoner then, I didn't really used cannabis, back when I made all of them. I'll tell you, I made Jay, Clerks, Mallrats, Chasing Amy, Dogma, James and Bob strike back, Jersey Girl, then Clerks II, then “Zack and Miri Make a Porno”, not being a stoner. During that time of my life, from birth till “Zack and Miri Make a Porno”, and I'm thirty-eight. I can count on two hands the amount of times that I had used cannabis, most of them being like right after high school. So, I wrote most of those movies not actually being a stoner, just knowing stoners. When I became a stoner was on “Zack and Miri Make a Porno.” I was working with Seth Rogen, who is one of the greatest stoners on the planet, the boy uses a lot of cannabis. But, he was the first productive stoner that I'd ever met in my life. He shattered the stereotype. He wasn't like Jay and Silent Bob at all. This was a guy who was shooting my movie, adlibbing three funnier movies, during my movie. Then he would go off set and hang out with Evan and write in the trailer. I guess they were working on Pineapple Express or something like that at that point. There was nothing about him that played like the stoner stereotype. He is hyper intelligent, funny. He is legit funny and sharp as a tack, superfast.

My friend Malcolm kept coming up to me and going, like, “Seth wants to use cannabis with you.” I said, “Why? And he goes “because he's a cinematic stoner icon and Silent Bob is THE cinematic stoner icon. You've got to use cannabis with him. It'll be amazing.” I said, “I don't use cannabis on the regular, let alone while I'm making a movie. How could I ever do that?” I was like, “No, I'm not doing that.” It wasn't till the end of the movie. More on the last day of shooting, we're just doing what they call pickup shots, like little leftover things, and it's just me and Seth basically. Castwise, everyone else is gone. So, I went up to him at one point, we were almost done with the day and I was like, “Hey, man, how about tonight you come up to the editing room? We'll watch some of the cut footage and we could use some of that cannabis I heard so much about.” And he goes, “Finally, ha ha ha!” He came to the editing room that night, and we watched the footage I’d cut together and some outtakes, and he had a wonderful California cannabis with him. He had it like in a pen, and he'd opened the pen and bam, there'd be this cannabis. We used it and I loved who I was while I was using it. It was the best version of me. I just kind of let go and no pretense whatsoever. It was not a performance. It was the real me at the core. And I was like, “Oh, I love this, it’s awesome.” Plus, it was just fun. I didn't start consuming right away, though. I didn't use again for about five or six months. And then I had some on the 4th of July here at the house with my wife. Nobody was here, she was like, “We should do something.” I was like, “Well, somebody gave us cannabis three Christmases ago” Let's use that. And she was “all right!” and we had that cannabis and it was a blast. We went out to eat, got a cab and ate a bunch of food, and then they came home. It was amazing. The next morning, I was like, “You know what, man? I'm a grown man. I am 38 years old and I have built enough at this point where, if I want to use cannabis every once in a while, I'm going to do it!” I started by saying, “I'm going to use it on the weekends.” And then, “Well, you know, I don't really do anything all week long, so I could probably use it all week long. Why am I waiting for the weekends? But as long as I'm using it, it has to be at night when all my work is done”. I

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you look at my career from 1994 to 2008, I make a lot of movies. I make a few comic books. If you look at my career from 2009 forward, it's this incredible journey everywhere. There's a podcast network, there's a TV show, there's me trying to direct somebody else's movie (unsuccessfully). There's me becoming a host who interviews people. With the addition of cannabis. What it allowed me to do is feel like, “Well, I'll try it. Why not try it?” Instead of fearing something like, “Well, I'm not going to get involved in that because what if I'm no good at it? And what if I suck what if people don't want me to do it?” And instead, you know, it works like this “but what if it was amazing?” that's the big difference. This just lowers the inhibitions, it inhibits your inhibitions and allows you to dream. That's it. And in dreaming, it's not going to give you a better idea. But in dreaming, that's where the cool things come from. Daydreaming, just flat out dreaming, wishing… Imagination is this incredible gift that we as human beings have that animals don't. We can create stories, narratives to tell one another and whatnot. had some at like seven o'clock at night, and then after a week of that, I said, “you know, there's no reason I have to wait till seven o'clock. I don't really have a real job.” So, I was like, “maybe I could start at noon. What a great day that would be.” After a week of that, I was “life would be so much better if the moment I woke up, I started up with cannabis”, and I became awake and baker. It was pretty cool. CWJ: Now that you are a user, how has the recreational use impacted your creative process? Because you developed a lot of programs such as the recent reboots of He-Man. Kevin Smith: Cannabis won't make you more creative, like it won't give you good ideas. What it does is lowers inhibition and inhibition will stop you from any number of things. Inhibition will stop you from reaching for some goal that you suddenly feel like “I'm not worthy. So, of course, that's why I don't have it.” You're inhibited by that. Cannabis removes the inhibition over creativity. The fear that somebody will be like, “That sucks; or why did you do that? Or that's stupid.” Suddenly, you use it away. Suddenly you're like, “Well, let's try it”, and you're more experimental. In my case specifically, you can chart my development as an artist, with the addition of cannabis to my life in 2008 at age 38. If

We live in the world and particularly in the age of social media, there's a lot of negativity. You try anything, people shot you down. You put up a picture of yourself on Instagram. You'll get no end to people being like, “You suck!” you know? So, it's a negative world out there and we're influenced by that negativity. We second guess ourselves because we don't want to be hurt or rejected. Maybe you got a good idea and you're like, “You know, I would want to try that. Why not me? I want to do this thing. I've seen other people do a thing like it. This is different. I want to take my shots, sing my song.” But, then that other voice comes in that’s just like, “you can't do that. Why do you think you would do that? Why hasn't it happened for somebody else? Why would it happen to you? You're no good.” Cannabis takes that voice away, turns the volume down and allows you to imagine the possibilities. It doesn't guarantee success, but it guarantees that you're going to take a step. You probably wouldn't have taken a creative step forward, and that's what life is forward momentum. And if you're in one place, you're stagnant, you're always going to want to be moving forward. And there's so much fear and so many inhibitors in this life that prevent us from moving forward other than just simply physically.

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CWJ: How do you feel about the medicinal use? On our magazine we focus a lot on it. We wanted to get your take on the side effects, which is to prevent health problems, to help with a lot of diseases. What is your take on that? Kevin Smith: I've got a 76-year-old mother with aches and pains, and she is closer to the end than to the beginning. And it's sad. People's bodies break down. And, you know, my mom is on literally, no joke, 25-30 different prescriptions. One for this one to counteract this. The effects of that one for that. All of them meant to keep her alive. Caviar makes a cream, a THC, CBD based topical. I sent her that once, and she wrote me back and called me to send her more of that. She said: “Is the first thing I've put on my legs that actually helps.” I've seen the medicinal effects. Cannabis has improved my mother's life to be sure. And she too used to have a bias against it, but then saw the health benefits, the medicinal benefits, and was like, “Why? Why were we told we couldn't have this my whole life?” I've seen the benefits in terms of my own personal health journey. This is an example that runs contrary to medical wisdom. But I'll tell you, regardless. I had a heart attack coming up in February, it'll be four years ago that I had a massive heart attack, and it was a Widow-maker, so I had an eighty percent chance of dying, twenty percent chance of living. And the doctor got it worked out, I'm still here. He put a stent in my heart, opened up the LAD artery that goes across your heart. It was packed with years of eating crap, food and stuff. Opened it up. Saved my life. I go to my doctor the next week, I had to convalesce. When I go see my doctor a week later, I say, “Look, I've been scared to ask this because cannabis's a big part of my life. I used a lot of cannabis the day, the heart attack, a lot because I was shooting a show.” A standup show for Showtime, a comedy special. And we were meant to do two, it was between the two shows that I had the heart attack. But it wasn't like I was in pain. I just couldn't catch my breath. It was weird. So, I was like, “Look, I've been scared to ask this since I've used so much cannabis. Is there a chance that's what triggered my heart attack?” And the doctor goes “no, in fact, the opposite, you were completely calm as they told you that you were literally dying of a heart attack. The doctor said, “usually that information, you know what happens? It compounds the heart attack because somebody is like, “what? I'm dying!” That creates more stress

. You were completely centered when you receive that information. And it didn't create more panic in you.” The doctor said to me, more or less, “that cannabis may have saved your life.” And I was like, I'm putting that on a t-shirt “Cannabis saved my life.” Now, I've told that story many places and many heart doctors have come out on Twitter “That isn’t true. That's not the case.” All I'm telling you is what I experienced and what my doctor told me. And my doctor said, in that instance, in terms of being told, “you are on the brink of death”, the worst thing that could have happened would have been for me to get scared and my heart rate to go even higher. But instead, since I was just chill, I was just like, “Oh, alright, well, let's try to do something about this, keeping it calm, keeping it cool.” And that made all the difference in that particular situation.

CWJ: That is incredible. Is there any advice that you have for readers, people who are getting into the industry all over the world? Kevin Smith: This is a product. I mean, people break it down to a product because we're in a world of sales. But, before it was a product; before it was a commodity, something that somebody could sell to somebody else because they were like, “Wow, that that's going to make me feel good.” This is something that just happened naturally, kids. Is out there and it was meant to be ingested. It's your birthright as a human being, as much as a tomato plant is, as much as a fern can be. It's a plant, which means it grows anywhere. You know what I'm saying? There's a reason they are beautiful flowers, like a bird of paradise cannot grow everywhere, but a cannabis plant can grow literally anywhere, and there's a reason that is accessible. It was meant to be in our system. It was meant to help. There have been too many proven medical efficacies that go along with cannabis to argue that like, “no, it's no medicinal help.” You don't have to be religious or scientific to understand that cannabis is everywhere for our benefit, it grows naturally, just like everything else grows naturally and balances out. Because it helps to spread that around man. Like the more people that can get off booze and use cannabis instead, what a better world it would be.

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Now, I'm not saying outlaw booze. I've got nothing against booze and stuff. Except, you know, if you're going to relax and unwind, that doesn't relax and unwind you, that just winds you up. If you want something, man, that's like even something that'll help you quit smoking cigarettes. I used to consume two packs of cigarettes a day up until I started on cannabis, and then one day while I was using it, I went to light a cigarette and I was like, “This is gross. I get nothing out of this, except maybe I want another cigarette.” But, when I use cannabis, I get everything out of it. I get ideas, I get hope, I get wisdom. I get fun. It's not killing me like this other stuff is. And slowly, I just stopped with the cigarettes. If I can use this, why would I ever use this? And my doctor told me when I had the heart attack, my cardiologist was like, “you are a cigarette user?” And I was like, “I haven't had a cigarette. I'm a cannabis user, a heavyweight user, but I haven’t had a cigarette since I was thirty-eight.” When I had the heart attack it had been about nine years since I'd stop using cigarettes, and the doctor was just like, “if you had still been a cigarette smoker, we wouldn't be having this conversation, you would have died, be gone; because your stuff would be so weak. The fact that you put that down when you did, made all the difference in that heart attack that you had.”

necessarily mine, but any cannabis brand whatsoever. Put your cigarettes down. You'll live longer and happier. Use cannabis instead. Use cannabis every day, a wise man once said. CWJ: That is amazing, Kevin. Thank you for your time. Kevin Smith: Thank you very much, it was a very nice interview, I had a great time.

We know for a fact that cigarettes are bad for you. And I'm not saying this is a medical fact, but experientially, for me, cannabis has been nothing but a bonus, a medical bonus in my life. I'm not trying to kill the cigarette industry and stuff. Do what you want, kids. But like, Jesus, if somebody told you that you're paying all that money to just smoke cancer and you're not getting it, you're chasing a dragon, you will never find again. That dragon is over there, man with one of these and stuff. Not

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CannaTrade

The Best Ideas to Get Started in a Growing Industry

Getting into this industry does not require big investments or limiting yourself to the scientific, financial, or medical fields. CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaTrade

Don't Miss Out on the Cannabis Business! Cannabis use normalization, whether for medicinal or recreational reasons, thanks to the expansion of its legalization and decriminalization, has led to the emergence of a wide range of direct and indirect business opportunities. Over the past few years, this industry has more than proven that it can be a highly lucrative market, with a steadily growing clientele and revenue expectations of over $21.6 billion by 2022. Serge Chistov, chief financial advisor to Honest Marijuana Company and president and founder of Serge Import LLC, explains, "It's very much like any other business. You have convenience stores for people to stop in, and then you have high-end or specialty options. There are also the producers, the packaging, and everything else. So there's a lot to do."

Entering this industry doesn't require significant investments or limiting oneself to scientific, financial, or medical. There is certainly room for everyone to start their own business in the cannabis industry. The key to success lies in finding the niche that best suits your skills and interests. Among the most innovative ideas are: Serge Chistov, chief financial advisor to Honest Marijuana Company

CANNABIS WORLD JOURNALS | EDITION NO. 20 |

CannaTrade Event/Celebration Planner

The key to success lies in finding the niche that best suits your skills and interests.

An ever-expanding field that ranges from birthdays, weddings, matchmaking parties, brunches, corporate meetings, educational seminars, product launches, or even events combined with activities such as painting or yoga. The possibilities are countless, and it is gaining more and more popularity. It can become a very lucrative option if you are interested in this type of business and have experience.

Hemp Clothing Design/Manufacturing As new cannabis uses are discovered, the range of materials derived from the plant is expanding. When the planet's conservation is a relevant issue, the value that hemp and cannabis bring to this market is incredible as organic, biodegradable materials. The materials' versatility creates a business opportunity for those interested in apparel that reflects such values and interests and who profess love for the plant.

Become a Security Consultant Let's remember that although the plant is becoming more and more normalized, its legalization is not absolute, and there are still many elements to be determined in the financial aspect. Add to this that cannabis is a very coveted item, so companies dedicated to its production and market are always looking for security systems: from personnel to camera systems and monitoring. It is a niche that can also be very lucrative.

Inns/Bed and Breakfasts/Airbnb As the decriminalization and legal consumption of cannabis expand, many more people are looking for spaces where they can enjoy the benefits of the plant in a safe environment, with like-minded people and enjoying new landscapes. This type of business is quite successful, and cannabis can generate incredible growth in the hospitality niche.

These are just a few examples of how the cannabis industry is full of opportunities to create a stable and profitable business. However, success will always depend on your level of interest, taking advantage of your strengths, and knowing how to detect opportunities. But never lose sight of are your goals and your passion for cannabis.

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How Does Cannabis Affect the Global Economy? According to data from New Frontier Data, legal cannabis sales worldwide until 2020 totaled US$ 23.7 billion, with 86% (US$ 20.3 billion) coming from the United States. Previously, when the media referred to cannabis, it was derogatory, associated with violence, drug trafficking, deaths, and murders. However, news has been changing according to the advances and scientific discoveries made, its positive effects in treating symptoms of certain diseases, its industrial benefits, and the progress of

legalization in certain countries. But, what about the social and economic impact? Either way, these factors are the most involved in the stigma attached to this plant. These contexts created the scenario that prevents us from seeing all its properties. Could it be that in addition to medicinal and industrial benefits, there really are economic and social benefits? There is no easy answer, as it depends on many variables and theories that can only be proven when put into practice, which is why it is necessary to analyze the economic behavior of the countries that have legalized cannabis.

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CannaTrade According to data from New Frontier Data, legal cannabis sales worldwide until 2020 totaled US$ 23.7 billion, with 86% (US$ 20.3 billion) coming from the United States. Although this figure seems quite considerable and very positive for the industry, there is still a long way to go, as the same report estimates that the value of illegal consumption for the same loss is US$ 391.3 billion.

This report forecasts that, in the next three years, legal sales will exceed US$ 51 billion worldwide and US$ 445 billion in illegal sales. By 2025, the annual growth rate of legal sales will reach an estimated 16.5%, while illegal sales only 2.6%, positively impacting the global economy on a greater scale. Excluding giants such as the United States and Canada, the legal cannabis markets from largest to smallest are: Germany with US$ 206,6 million, Israel with US$ 158 million, Puerto Rico with US$ 145 million, and the Netherlands with US$ 108 million; the list is followed by Australia, Italy, Jamaica, Uruguay, Colombia, United Kingdom, Malta, Czech Republic and at the end of the list, Denmark with US$ 0.2 million. To conclude this analysis, we will use as a basis the words of the former president of Uruguay, José Mujica, who stated during his term of office that the motivation for being the first country to legalize medical cannabis in Latin America "was to steal the market from drug trafficking." In other words, if the legal cannabis industry continues to grow and more countries allow its use, the impacts at a global level will be highly significant, consequently affecting the social context and access for more people to receive the benefits of the plant. José Mujica, Uruguayan former president CANNABIS WORLD JOURNALS | EDITION NO. 20 |

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CANNABIS AND THE WORK ENVIRONMENT The prohibition of cannabis in the workplace, even for medicinal purposes, lies in two main factors, the first of which is stigma. The second is regulation. CANNABIS WORLD JOURNALS | EDITION NO. 20 |

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Unfortunately, cannabis is still considered dangerous, making employers do whatever it takes to prevent their employees from consuming it and impacting their quality of work.

For companies, the use of cannabis by their employees has been a battlefield. The stigma surrounding the plant's use and regulatory contradictions have resulted in the lack of protocols under which to act regarding cannabis use in the work environment. In most countries, the use of cannabis in the workplace is prohibited. It also applies to employees attending work under the influence of the plant, even if employees use it for medicinal purposes and its use is supported by law in their country of residence, making them certified patients. The prohibition of cannabis in the workplace, even for medicinal purposes,

lies in two main factors. The first is stigma. Although we are a long way from the past when the plant was considered almost as harmful as opioids, we cannot deny that it is still regarded as dangerous. Thus, making employers do whatever is necessary to prevent their employees from consuming it and impacting their quality of work. The second and perhaps the most crucial factor is the contradictions in cannabis regulation. In cases such as the United States, where it is illegal at the federal level, consumers are at a disadvantage. It gives employers a reason to conduct anti-doping tests, sanction, or fire employees who consume the plant.

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The same is true for countries like Canada, where cannabis, although legal, is not an approved drug by the department that regulates food and medicine. It puts employees who use medical cannabis in the crosshairs. Adapting the Workplace Adapting a workplace to legalization is a proactive task. Human resources policies and procedures should update to address what is (or is not) acceptable in your workplace concerning legalization. Educate employees on the potential risks and benefits of cannabis and train managers to screen for cannabis abuse and/or impairment. What Options Do Employees Have?

Knowing the policies about cannabis use and the healthcare system in your country can be powerful tools for employees who use the plant. Misinformation can lead them to fall prey to unfair treatment that may border on illegality. Therefore, employees must be aware of and use their rights as medical cannabis users.

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Diverging Realities: Unaffordable Pricing of Medical Cannabis CANNABIS WORLD JOURNALS | EDITION NO. 20 |

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£4,000 a month for epilepsy treatment with cannabis to subsidy programs for medical cannabis patients such as Project 21.

Previously, irregularly sold cannabis used to be consumed more, and it was cheaper, according to a survey in England and Wales in 2019. It showed that 1.4 million people bought the plant for chronic illnesses and spent between £99 and £199 a month.

Cities are filling up with dispensaries, brands are debuting new product lines, and the medical community is increasing the prescription of medical cannabis. However, one issue continues to cause problems and constraints for the industry: pricing, especially for patients using the plant for medical purposes. The price discrepancy between the illegal and legal markets was significant for many. Currently, medical prices continue to represent a challenge for patients and families. That could be counterproductive for the industry, considering that legal medical cannabis is one of the most relevant sectors of the market.

Currently, prices between irregularly sold cannabis and dispensaries are similar. Overall, the average cost of medical cannabis varies between £7.5 and £15 per 100 mg, which would be a total of £150 to £250 per month of CBD and THC treatment. In addition to this, to acquire a prescription, one must attend a consultation with a licensed medical specialist, with initial visits ranging from £90 to £200 and follow-up visits costing between £65 and £150.

To illustrate, if you want to buy a can of soda anywhere in the world, the difference would be between $1 and $2 in most cases. However, a gram of medical cannabis can range from $5 to $20, while an ounce of oil could range from $200 to $400 depending on where it is bought.

United Kingdom Patients in the UK have come a long way with prices, from families paying £2,500 to

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formula. If the medical prescription is a multi-cannabinoid compound, the price will depend on the cost of each cannabinoid per milligram. Isolated CBD and THC cost $0.05 per mg. And a 1:1 ratio of THC and CBD oil costs $0.08 per mg. A patient can pay as much as $300 for a bottle of cannabis oil.

United States The price differences between states represent significant gaps that make it difficult for qualified patients to access medical cannabis. An ounce of cannabis ranges from $210 $240 in states like Oregon, Washington, and Colorado. However, it can cost anywhere from $360 to $600 in states like Virginia, North Dakota, and the District of Columbia. As an example, in Washington, 3.5 grams of cannabis costs $35, while in Virginia, that same amount is priced at $65. This price discrepancy affects people in states where medical cannabis is more expensive; some opt for self-cultivation. However, not all states where it is legal allow the cultivation of cannabis plants.

The price of cannabis flowers ranges from $12 to $17 per gram. The medical cannabis industry is a phenomenon that benefits not only the patient community but also the country's economy; however, product segmentation and pricing could become a limiting factor in its growth and profitability.

Australia Australia is another country where patients buy cannabis from an irregular seller because the legal product is too expensive. On average, a patient spends $270 per month, depending on the cannabinoid

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CannaMed According to state medical laws, the evidence regarding the treatment of most diseases with cannabis is still not sufficient. Currently, many people report using cannabis as a substitute for prescription drugs, usually without the knowledge of their primary care providers.

In the United States, there is a health team called primary care providers (PCP), a group of physicians who have the first contact with patients to diagnose the disease and recommend possible treatment. The PCP may refer the patient for a second, more specialized medical evaluation with another medical expert called a Physician. The patient can also access this physician on their own, but it is usually more expensive than the PCP.

Medical Cannabis Is a Right for All: How the Communication Between Patient and Healthcare Professional Affects the Prescribing Process

Currently, many people report using cannabis as a substitute for prescription drugs, usually without the knowledge of their PCP. This lack of integration raises serious concerns, for example, in using cannabis to treat sensitive medical conditions that require established, nearly irreplaceable treatment. Still, others use it to treat conditions for which there is limited evidence of the therapeutic value of cannabis.

Although 35 U.S. states have enacted medical cannabis programs, distrust of the health care system is a difficulty that disconnects this law from reality. But what is the reason for this phenomenon, if access to medical cannabis should be free? One of the main reasons can be attributed to the fact that, in 1970, Cannabis was listed as a Schedule I compound in the U.S. Controlled Substances Act, indicating that it is an element of high abuse potential and no accepted therapeutic use.

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Clearly, with increasing research and scientific studies supporting the therapeutic value of cannabinoids, as it happens in the reduction of chemotherapy-induced nausea and vomiting, chronic pain, and multiple sclerosis-related spasticity, the landscape has changed. However, according to state medical laws, the evidence for treating most diseases with cannabis is still not sufficient.

In addition, patients who use cannabis feel that they cannot approach and discuss their use with healthcare professionals, for fear of stigma or legal problems. Some institutional policies prevent physicians from recommending medical cannabis and patients may lose their employment due to a positive occupational health test result, even if they have a medical cannabis license. These concerns are based on a 2020 survey of 371 physicians in the state of Michigan, only 34% of medical personnel assume that cannabis was a Schedule I drug, and 80% acknowledged that they needed to be more informed and educated about the therapeutic benefits of this plant. In addition, it was reported that the most common way for physicians to obtain information related to the use of medical cannabis is through patients, other specialized health professionals, news, and medical journals, rather than formal training by medical programs.

Although 80% reported that their PCP knew that they were currently using medical cannabis, nearly half commented that their provider was often unaware, deciding to take time to report it. Only 14% obtained their medical cannabis authorization from their PCP, with the remainder going to outside physicians (Physicians) and dispensaries to obtain it, but the vast majority do so without being licensed. Both men and women reported using cannabis to treat various problems such as chronic pain (31%), post-traumatic stress disorder (PTSD) (7%), arthritis and headaches (6%), anxiety, panic attacks and cancer (5%), depression and stress (4%).

For this reason, 64% of medical cannabis users participating in the study initiated the use of the plant and its derivatives based on their own experiences, compared with 24% who followed the advice of their PCP.

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CannaMed Most patients felt that their primary care physicians' knowledge of cannabis was poor and insufficient, and they did not trust their ability to manage treatment. Similarly, they reported that, upon obtaining their medical cannabis license, the PCP had no further involvement in their current medical care. These individuals opted to use cannabis in exchange for antihistamines, anticonvulsants, antidepressants, among other drugs. This research is valuable because it emphasizes the relevance of medical cannabis and conventional medical care, including cannabis education of health professionals, the importance of the endocannabinoid system, benefits, and care in relevant therapeutic contexts of phytocannabinoid compounds. The patient's

cannabis knowledge should be reinforced, to understand the risks of abandoning a conventional therapy without the proper medical support. Cannabis is everyone's right, it is the cultural appropriation of a plant synonymous with resistance and autonomy, which has overcome legal obstacles and continues to offer great benefits to health and human wellbeing. The importance of education and access to information is crucial for progress and the search for alternatives to improve people's quality of life.

Source: Boehnke, K. F., Litinas, E., Worthing, B., Conine, L., & Kruger, D. J. (2021). Communication between healthcare providers and medical cannabis patients regarding referral and medication substitution. Journal of cannabis research, 3(1), 1-9.

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Cannabis-based Medications Available on the Market. The Food and Drug Administration of the United States (FDA) has approved drug formulations based on natural and synthetic cannabinoids. Some of them are Dronabinol, Nabilone, Nabiximol, Epidiolex®, among others. They are used to treat patients suffering from nausea caused by chemotherapy, stimulate appetite, treat consumptive syndrome (involuntary loss of more than 10% of body weight) resulting from immunodeficiency syndrome (AIDS), and many other conditions.

ccording to pharmacological research, phytocannabinoids are all chemical substances that bind to receptor proteins such as CB1 and CB2, present in our organism. The first receptor was cloned in the laboratory of Tom Bonner, in 1990, and it was located in the central nervous system of rodents and humans. They are responsible for the physiological processes of neurons and neuronal activation through the active compounds of the plant and synthetic cannabinoids.

Currently, there are several products derived from cannabis for medicinal purposes, their consumption depends on the concentration and chemical profile of the phytocannabinoids present in the plant, for the treatment of different physical and mental disorders. Cannabis-based medicines are products that require authorization for use in many countries and their quality is certified by good manufacturing practices.

Methods of administering. Source: https://nutricionyfarmacia.es

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Some of its most common commercial presentations are extracts, resins, oils, creams, lotions, edibles, among others. The routes of administration most recommended by health specialists are oral or sublingual, inhalation, transdermal or percutaneous, rectal or vaginal. Each of these methods has its characteristics, differentiated by their therapeutic uses depending on the effects sought.

Synthetic cannabinoids are produced to simulate the effects of phytocannabinoids in the body. Several countries have authorized using these drugs for treatment or specific diseases. They sold under medical prescription.

Marinol commercial presentation. Source: https://canamo.net/noticia

Dronabinol is a synthetic cannabinoid that interacts with certain cell receptors, especially in the brain. Physicians use this drug to increase appetite, control weight loss in HIV-infected patients and vomiting caused by chemotherapies. Dronabinol is generally administered orally, and its presentation is usually in capsules or liquid solution. It is commercially available under the names Marinol® and Syndros®.

Nabilone, like Dronabinol, is a synthetic cannabinoid, similar to Δ-9 tetrahydrocannabinol (Δ9-THC), the psychoactive component of cannabis. This drug is administered orally in capsules and is generally consumed 2 to 3 times a day when a patient is undergoing chemotherapy treatments. For its consumption, a doctor's prescription is required.

Nabiximol is another synthetic cannabinoid, based on THC and CBD, it acts by binding to the CB1 and CB2 receptors, which are located in the immune system and Commercial presentation Syndros and Cesamet. peripheral tissues, inhibiting the impulse that causes Source: https://canamo.net/noticia. muscle spasm, which can help improve the quality of life of patients with multiple sclerosis. It is administered orally (pulverized) and subsequently absorbed through the mucosa, its active ingredient enters the bloodstream and is distributed throughout the body. Its commercial presentation for sale is Sativex®.

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There are several products derived from cannabis for medicinal purposes, their consumption depends on the concentration and chemical profile of the phytocannabinoids present in the plant.

Synthetic cannabinoids are produced to simulate the effects of phytocannabinoids in the body. Cannabidiol (CBD) is one of the main natural active compounds of the cannabis plant, however, it can be found in synthetic formulations such as Epidiolex®, which is most often used in the treatment of epilepsy, anxiety, pain, Parkinson's disease, Crohn's disease, and many other conditions.

CBD prevents the breakdown of chemicals in the brain that affects pain, mood, and mental function, and may reduce the symptoms of psychosis associated with illnesses such as schizophrenia. It is used to treat seizures in patients with LennoxGastaut syndrome, Dravet's disease, or tuberous sclerosis. It is generally administered orally in capsule or solution form.

So far, research shows that the use of cannabinoids is effective in the control of some types of chronic pain. Studies affirm that cannabis could be a very useful alternative to drugs such as opioids without generating side effects in the patient. Thus demonstrating the importance of allowing access to cannabis-based medicines to treat various diseases.

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Disclaimer: Cannabis World Journals from its position as a purely educational journal is not responsible for the issuance of personal opinions for informational purposes. For the proper, responsible, and safe use and handling of cannabis, consult the laws of your country and/or your family doctor or specialist.