Oxurion Brand Bible 2018

Advancing Science.

Enhancing Vision.

Brand bible and style guide

Advancing Science.

Enhancing Vision.

Brand bible and style guide

Table of contents

Table of contents Formerly known as A new corporate brand: Oxurion Oxygen & Orion Our tagline At a glance Our mission Our hopes and dreams Our personality Brand elements and style guide

4 6 7 8 10 18 19 20 23

Logo 25 Color palette

32

Typography

34

Communication tools

54

Letterhead & envelopes

54

Business cards

56

Compliment cards

57

Note block

58

Presentation 59 Website 60 Perspectives magazine and blog

61

Roll-up banner and Pop-up stand

62

Brand architecture Contact information

63 64

Imagery 37 Icons and design features

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Oxurion Brand bible & style guide

Oxurion

Formerly known as ...

Formerly known as ThromboGenics, Oxurion builds on a yearlong expertise in the field of back of the eye disorders. We remain the same company, built on the same knowledge platform of profound scientific know-how.

At our core Advanced research addressing unmet medical needs in ophthalmology.

An aspiring new name to better reflect the company’s focus and ambition.

The renaming comes at a moment when the company is stepping up its drug development efforts for back of the eye diseases.

2018

September

2018

April

Good progression clinical trials Positive data from the phase I/IIa clinical trial with THR-317, initiation of the phase II clinical trial.

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Focus on diabetic eye disease

IPO

The company focuses its strategy on diabetic eye disease, while providing a platform to develop therapies for other ophthalmological indications.

2016

ThromboGenics is listed on Euronext Brussels

2013

March

January

2006

July

2001

January

Foundation Jetrea Commercial launch of Jetrea in the U.S.

ThromboGenics NV is founded, with an R&D scope in cardiovascular, oncology and opththalmology programs.

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Oxurion  Brand bible & style guide

A new corporate brand

A new corporate brand is a natural step. It confirms our evolution, embraces our core expertise and reflects our desire to continue building on what we achieved in the past.

But we also evoke our aspirations for the future.

We are driven by the ambition to expand our activities into new areas.

We are moving forward as a global biotechnology company, developing next generation therapies for back of the eye disorders, with a focus on diabetic eye disease and beyond.

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Oxygen & orion

Oxygen & Orion Our name Oxurion derives from a combination of ‘Oxygen’ and ‘Orion’, a character from Greek mythology.

Oxygen Raising oxygen levels in cells plays an important role in preventing or reversing key factors leading to diabetic eye disease. Referencing this word reflects our mission to target these factors with unique therapies, as early as possible, to deliver an optimal benefit to patients.

Orion Orion was a Greek mythological figure who was blinded, but ultimately had his vision restored

by Helios, god of the sun. This reference captures our mission - to fight visual impairment and blindness globally.

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Oxurion  Brand bible & style guide

Our tagline Our tagline reflects our core activities and purpose We translate our scientific expertise into novel therapies in ophthalmology. It is our ultimate goal to improve vision for patients with chronic eye disorders.

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Our tagline

“We are a biotech company, our scientific knowhow is the basis of everything we do”

“Proactive attitude” “Combined reference to our scientific insights, our ambitions and our core area of expertise”

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Oxurion  Brand bible & style guide

At a glance Oxurion is a biopharmaceutical company developing treatments to preserve vision for patients with diseases affecting the back of the eye. It has engineered a diverse portfolio of disease-modifying drug candidates, including treatments for diabetic eye disease, a leading cause of blindness in people of working age worldwide.

Oxurion owns the global rights to Jetrea (ocriplasmin), the only pharmacological vitreolysis drug approved for the treatment of symptomatic vitreomacular adhesion (in the U.S.) and vitreomacular traction (outside the U.S.).

Oxurion is headquartered in Leuven, Belgium, and is listed on Euronext Brussels under the symbol OXUR.

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“We discover new pathways to answer unmet medical needs in ophthalmology.�

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“We research innovative compounds for the treatment of chronic eye disorders, with a focus on the back of the eye.�

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“We develop and commercialize next generation therapies for back of the eye disorders.�

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“We collaborate and partner with leading universities, biotechnology companies and pharmaceutical companies worldwide.�

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“We execute and expand our drug development pipeline targeting the key segments of the diabetic eye disease market.�

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“We focus on the patient in everything we do.�

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Oxurion  Brand bible & style guide

Our mission Our goal is to prevent vision loss and fight blindness worldwide by developing and delivering nextgeneration treatments in ophthalmology. We aim to lower the burden of treatment for patients and enhance practice management for physicians.

We develop innovative compounds that each target a distinct, unexplored pathway to answer unmet medical needs in ophthalmology, with a focus on back of the eye disease.

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Our hopes & dreams

Our hopes & dreams Our current pipeline of unique drug candidates is focused on new treatment approaches for diabetic eye disease, and we will continue leveraging our expertise in diseases affecting the back of the eye to expand our pipeline to address additional indications with high unmet needs.

We are committed to innovation through crossdisciplinary and cooperative research across the globe. Collaborating with stakeholders worldwide, we aim to deliver solutions enabling equal, affordable vision preservation for all people.

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Oxurion  Brand bible & style guide

Our personality We are explorers.

Cross-disciplinary action enables us to be nimble and agile without sacrificing quality.

We don’t rely on a technology platform: ophthalmology is our science base.

We build on a deep expertise and broad experience in the field of back of the eye disease.

We are a modest company, open and available to any form of collaboration or partnership.

In all our activities, we focus on our ambition: finding novel treatments for back of the eye disorders.

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Agile

Ambitious

Aspiring

Innovative 21

Design features

Tools

Imagery

Our personality

Logo

Typography

Bariol

Brand elements and style guide

ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 0123456789

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Oxurion  Brand bible & style guide

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Logo

Logo Shown here are two versions of the Oxurion logotype.

There is a version with tagline and a version without tagline.

Oxurion is a registered trademark, the ® should always be used.

Safety zone A clear space area is defined around the logotype.

No graphic elements can be placed within this area.

Use tagline There are two versions of the logo available: with tagline and without tagline.

The version with tagline is preferred, except when: ••

the available space is too limited

••

the logo is used in combination with other logos, for example in sponsoring campaigns

••

the logo is used in combination with a product logo (see brand architecture on pg 63)

The safety zone is defined by the height of the “I”.

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Oxurion  Brand bible & style guide

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Positive version with tagline

Diapositive version with tagline

This is the main and basic versions of the Oxurion logo with tagline. This version is preferred and will be most used, on a white or light coloured background.

When the logo is placed on a dark blue background, we use the diapositive version of the Oxurion logo with tagline, as shown above.

Logo

Diapositive version

Positive version

When the logo is placed on a dark blue background, we use the diapositive version of the Oxurion logo, as shown above.

This is the main and basic versions of the Oxurion logo.

This version is preferred and will be most used, on a white or light coloured background.

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Oxurion  Brand bible & style guide

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Black version with tagline

White version with tagline

When the logo is used for print in black and white., we use the black version of the Oxurion logo with tagline, as shown above.

When the logo is placed on a green, black or dark background, we use the white version of the Oxurion logo with tagline, as shown above.

Logo

White version

Black version

When the logo is placed on a green, black or dark background, we use the white version of the Oxurion logo, as shown above.

When the logo is used for print in black and white., we use the black version of the Oxurion logo, as shown above.

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Oxurion  Brand bible & style guide

Logo on images The logo can be placed on images, but only when the readability is guaranteed. Respect the minimal size and use a positive version on a light background and a white version on a dark background

Minimal size The minimum size of the logo with or without tagline is 40 mm. Make sure the tagline is always readible, otherwise choose the version without tagline.

40 mm

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40 mm

Logo

Incorrect use The Oxurion logo is the most important element of our identity.

You should use the logos as they become delivered. You can never change the logos!

Shown here are examples of incorrect usage of the Oxurion logo.

Colors of the logo can not be changed

Tagline underneath the logo can not be moved

Do not place a shadow behind the logo

The logo may not be used as an outline version

The proportions of the logo can not be changed

The logo may not be rotated

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Oxurion Brand bible & style guide

Color palette

PMS 2767 CMYK C 92 M 73 Y 19 K 57 RGB R 18 G 40 B 75 HEX #12284b

Primary colors These are the primary colors of the Oxurion brand.

They play a very important part in the identity of Oxurion.

We can use them in many cases, like for backgrounds, titles, subtitles, and graphic elements.

In general, it is recommended to use the same proportions as in the logotype; use more blue than green.

PMS 346 CMYK C 55 M 0 Y 50 K 0 RGB R 117 G 193 B 149 HEX #75c195

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Color palette

CMYK C 90 M 56 Y 60 K 50 RGB R 8 G 59 B 59 HEX #083b3b

Secondary colors These are the secondary colors of the Oxurion brand.

They are less important than the primary colors.

CMYK C 0 M 80 Y 60 K 20 RGB R 198 G 65 B 67 HEX #c64143

We use them for small details in different applications.

For example: website, brochures, folders, magazines, etc.

Their role is to add some accents and focus where necessary.

CMYK C 0 M 60 Y 70 K 0 RGB R 241 G 125 B 75 HEX #f17d4b

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Oxurion Brand bible & style guide

Typography Primary font : Bariol Bariol is a rounded, slightly condensed typeface.

Friendly, yet formal and serious. Thanks to its sober shapes and simple construction, this font is very readable even at nearly microscopical scales.

The lighter weights have a remarkable elegance that is evident in large sizes. It has different stylistic alternatives and ligatures.

Bariol

Thin Light Regular Bold ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 0123456789 ‘?’“!”(%)[#]{@}/&\<-+÷×=>®©$€£¥¢:;,.* (also available in italics)

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Typography

Nunito

Extra-Light Light Regular Semi-Bold Bold Extra-Bold Black

Websafe font : Nunito (Google font) Nunito is a well balanced sans serif typeface superfamily.

This font is html-safe and can be used for all online applications.

ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 0123456789 ‘?’“!”(%)[#]{@}/&\<-+÷×=>®©$€£¥¢:;,.* (also available in italics)

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Oxurion Brand bible & style guide

MS Office font : Calibri Calibri is a modern sans serif family with subtle roundings on stems and corners. It features real italics, small caps, and multiple numeral sets. Its proportions allow high impact in tightly set lines of big and small text alike. Calibri’s many curves and the new rasteriser team up in bigger sizes to reveal a warm and soft character.

This font is preferred for all MS Office applications.

In Office 2007, it replaced Times New Roman as the default typeface in Word and replaced Arial as the default in PowerPoint, Excel, Outlook and WordPad.

Calibri Regular Bold

ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 0123456789 ‘?’“!”(%)[#]{@}/&\<-+÷×=>®©$€£¥¢:;,.* (also available in italics)

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Imagery

Imagery Sometimes, images are more powerful than words.

Photography is an important element in the brand identity of Oxurion. Where feasible, we prefer realistic purposefully shot images to stock photography.

We recommend the use of images that refer to one of the key aspects of our corporate identity: ••

Science

••

Vision and eyesight

••

People: patients, end benefit, everyday activities

••

People: team members and researchers, international environment

••

Back of the eye

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Science Science plays an central role in everything we do.

From preclinical research to clinical development, it is critical that we remain scientifically sound.

Images referring to science should refer to research and development or ophthalmology. Preferably, they are shot in the labs of our company and show either scientific detail, or our people at work.

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39

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Imagery

Vision and eyesight Vision and eyesight ar both abstract notions, but since they relate directly to our core business we like to use images that infer these notions indirectly.

Typical images show eyes with a strong expression.

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

People: patients and end benefit We aim to deliver solutions enabling equal, affordable vision preservation for all people.

People who suffer from back of the eye diseases, experience problems with everyday activities like reading, driving the car, cooking or cleaning.

Pictures of people in an everyday setting underline our commitment to the patient.

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Imagery

People : team members and researchers We are a company where people – and especially scientists – play a key role as drivers of progress.

In a general context, images should preferably include people from around the world, mostly between 35 and 99 years old.

International environment Oxurion operates on a global scale. Images should reflect our international character and show people from all around the world.

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OXURIONâ&#x20AC;&#x201A; Brand bible & style guide

Back of the eye Oxurion is focused on researching and delivering treatments for back of the eye disorders.

Illustrations and images of the back of the eye (retina) are an essential part of the Oxurion imagery.

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Oxurion Brand bible & style guide

Icons and design features Corporate symbolism: the X The “X” is the most important part of our logotype. It symbolizes a number of things, which are not to be named but remain in the background as unspoken suggestions: we are focused, oriented towards the future, in search of innovation, ...

Meanwhile the X makes for an interesting addition to images and designs. It can be used on its own, in a background or on a picture. It is an instrument for adding visual interest, and we encourage its creative use.

It can and should be cut outside the frame.

Most used. The green version should be used on a light background or on a picture.

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Most used. The white version should be used on a dark background or on a picture.

Rarely used. The blue version only used for one colour print.

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Icons and design features

Left or right half of the Oxurion X Half of the X makes for an interesting addition to images and designs. It can be used in combination with a background or a picture.

It is an instrument for adding visual interest, and we encourage its creative use. It can and should be cut outside the frame.

Left half of the X. Should be used in combination with a background or a picture.

Right half of the X. Should be used in combination with a background or a picture.

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Other graphical elements Diagonally intersecting lines also refer to the x in Oxurion.

They can form colored triangles and cut-outs for images.

These graphical elements are mostly used for screen applications, such as the corporate website or corporate presentation.

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Oxurion Brand bible & style guide

Communication tools It is important to maintain a consistent look across all of Oxurion’s internal and external communication channels.

The following examples show correct and inspiring use of visual aspects of the new brand.

Letterhead & envelopes This is an example of our letterhead and envelope.

High resolution Indesign or PDF formats are available, as well a MS Word template of the letterhead.

USA ThromboGenics Inc. - subsidiary of Oxurion nv 101 Wood Avenue South · Suite 610 · Iselin · NJ 08830 · USA Tel: +1 732 590 2900 · Fax: +1 732 590 2890 www.oxurion.com

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Communication tools

Gaston Geenslaan 1 3001 Leuven

Gaston Geenslaan 1 3001 Leuven

Gaston Geenslaan 1 3001 Leuven

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Oxurion Brand bible & style guide

Business cards This is an example of our business cards.

They are available with blue or white back side.

Native files are available.

Wouter Piepers Global Head of Corporate Communications & Investor Relations m +32 (0) 478 33 56 32 t +32 (0) 16 75 13 10 e wouter.piepers@oxurion.com

HQ Gaston Geenslaan 1 · 3001 Leuven · Belgium USA 101 Wood Avenue South · Suite 610 · Iselin · NJ 08830 · USA www.oxurion.com

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Communication tools

Compliment cards These are our compliment cards.

They are available with blue or white back side.

Native files are available.

With compliments

USA ThromboGenics Inc. - subsidiary of Oxurion nv 101 Wood Avenue South · Suite 610 · Iselin · NJ 08830 · USA Tel: +1 (732) 590 2900 · Fax: +1 (732) 590 2890 · www.oxurion.com

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Note block This is an example of our note block.

Native files and high res pdf files are available.

www.oxurion.com

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Communication tools

Presentation Our Oxurion Powerpoint template is built in 16:9 proportion.

It consists of a title slide, chapter slides and content slides, using the brand colors, graphic elements and typography.

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Corporate website On the corporate website www.oxurion.com you can find all information about our company: research activities, investor related information, the history of our company and our latest news and events.

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Communication tools

Perspectives magazine and blog Oxurion has its own magazine and online blog Perspectives.

In Perspectives (online or in print), people can read background articles about our research and development activities, but the magazine and blog also contain patient stories, interviews with scientists and quotes from stakeholders and partner organizations.

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Rollup and minibooth A pop-up minibooth and a set of rollups are being used at science- or investor-related events.

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Brand architecture

IMPORTANT NEW PRODUCT INFORMATION

(ocriplasmin) 0.375 mg/0.3 mL solution for injection, for intravitreal injection

Brand architecture Global corporate brand Oxurion is a globally recognized corporate brand.

Everything we do is signed “Oxurion”.

Endorsed product brand As the company owns the global rights to JETREA®, a product commercialized until now under its own name, we want to continue to capitalize on the brand equity built around it in the past.

Give this product a separate position as a corporate brand in our brand landscape. We endorse it by adding “by Oxurion” as a strap line in all instances.

This shipment contains the ready diluted formulation of JETREA® (ocriplasmin) 0.375 mg/0.3 mL solution for injection, for intravitreal injection.

PLEASE PROVIDE THIS INFORMATION TO THE PHYSICIAN

Concentration in the vial Volume in the vial Preparation Injection Storage and handling

Original formulation: Concentrate

New formulation: Ready Diluted

2.5 mg/mL

1.25 mg/mL

0.5 mg in 0.2 mL

0,375 mg in 0.3 mL

Dilution by adding 0,9% NaCl Inject 0.1 mL solution

Inject 0.1 mL solution

Frozen (-20° ± 5°C) Up to 8 hours room temperature Do not refreeze after thawing

Price Color of cap

No price difference Orange

Blue

For more information on the new formulation, please refer to the JETREA® (ocriplasmin) 0.375 mg/0.3 mL solution for injection Summary of Product Characteristics, Labeling and Package Leaflet found at www.ema.europa.eu.

If you have any questions or require more information about the new formulation, please contact Oxurion NV at: Address: Oxurion NV, Gaston Geenslaan 1, B 3001 Leuven, Belgium

Telephone: +32 78 050 022 E-mail: info@jetrea.com

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Oxurionâ&#x20AC;&#x201A; Brand bible & style guide

Contact information Oxurion Wouter Piepers Global Head of Corporate Communications and Investor Relations Gaston Geenslaan 1 B-3001 Heverlee Belgium T: +32 (0) 16 75 13 10 M: +32 478 33 56 32 F: +32 16 75 14 66 wouter.piepers@oxurion.com www.oxurion.com

Design & Copywriting Cantilis www.cantilis.be

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Contact information

www.oxurion.com

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